{"id":"https://openalex.org/W2136162563","doi":"https://doi.org/10.1093/jac/dkh013","title":"Dyslipidaemia associated with antiretroviral therapy in HIV-infected patients","display_name":"Dyslipidaemia associated with antiretroviral therapy in HIV-infected patients","publication_year":2003,"publication_date":"2003-12-04","ids":{"openalex":"https://openalex.org/W2136162563","doi":"https://doi.org/10.1093/jac/dkh013","mag":"2136162563","pmid":"https://pubmed.ncbi.nlm.nih.gov/14645323"},"language":"en","primary_location":{"id":"doi:10.1093/jac/dkh013","doi":"https://doi.org/10.1093/jac/dkh013","is_oa":true,"landing_page_url":"https://doi.org/10.1093/jac/dkh013","pdf_url":"https://academic.oup.com/jac/article-pdf/53/1/10/1985728/dkh013.pdf","source":{"id":"https://openalex.org/S124275759","display_name":"Journal of Antimicrobial Chemotherapy","issn_l":"0305-7453","issn":["0305-7453","1460-2091"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Antimicrobial Chemotherapy","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://academic.oup.com/jac/article-pdf/53/1/10/1985728/dkh013.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5046270633","display_name":"Leonardo Calza","orcid":"https://orcid.org/0000-0002-1895-1504","observed_orcids":["https://orcid.org/0000-0002-1895-1504"]},"institutions":[{"id":"https://openalex.org/I4210097083","display_name":"IRCCS Azienda Ospedliero-Universitaria di Bologna Policlinico di Sant'Orsola","ror":"https://ror.org/00t4vnv68","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210097083"]},{"id":"https://openalex.org/I9360294","display_name":"University of Bologna","ror":"https://ror.org/01111rn36","country_code":"IT","type":"education","lineage":["https://openalex.org/I9360294"]}],"countries":["IT"],"is_corresponding":true,"raw_author_name":"L. Calza","raw_affiliation_strings":["Department of Clinical and Experimental Medicine, Division of Infectious Diseases, University of Bologna Alma Mater Studiorum, S. Orsola Hospital, Via Massarenti 11, I-40138 Bologna, Italy. calza@med.unibo.it","Department of Clinical and Experimental Medicine, Division of Infectious Diseases, University of Bologna \u2018Alma Mater Studiorum\u2019, S. Orsola Hospital, Via Massarenti 11, I-40138 Bologna, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Clinical and Experimental Medicine, Division of Infectious Diseases, University of Bologna Alma Mater Studiorum, S. Orsola Hospital, Via Massarenti 11, I-40138 Bologna, Italy. calza@med.unibo.it","institution_ids":["https://openalex.org/I4210097083","https://openalex.org/I9360294"]},{"raw_affiliation_string":"Department of Clinical and Experimental Medicine, Division of Infectious Diseases, University of Bologna \u2018Alma Mater Studiorum\u2019, S. Orsola Hospital, Via Massarenti 11, I-40138 Bologna, Italy","institution_ids":["https://openalex.org/I4210097083","https://openalex.org/I9360294"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5046270633"],"corresponding_institution_ids":["https://openalex.org/I4210097083","https://openalex.org/I9360294"],"apc_list":{"value":2869,"currency":"GBP","value_usd":3784},"apc_paid":null,"fwci":9.1684,"has_fulltext":true,"cited_by_count":178,"citation_normalized_percentile":{"value":0.97936574,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":93,"max":100},"biblio":{"volume":"53","issue":"1","first_page":"10","last_page":"14"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11655","display_name":"HIV-related health complications and treatments","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2711","display_name":"Emergency Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11655","display_name":"HIV-related health complications and treatments","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2711","display_name":"Emergency Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10394","display_name":"Lipoproteins and Cardiovascular Health","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10526","display_name":"HIV/AIDS drug development and treatment","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/dyslipidemia","display_name":"dyslipidemia","score":0.9819999933242798},{"id":"https://openalex.org/keywords/hiv-infection","display_name":"HIV infection","score":0.746999979019165},{"id":"https://openalex.org/keywords/highly-active-antiretroviral-therapy","display_name":"highly active antiretroviral therapy","score":0.9919999837875366},{"id":"https://openalex.org/keywords/protease-inhibitors","display_name":"protease inhibitors","score":0.9900000095367432},{"id":"https://openalex.org/keywords/hypertriglyceridemia","display_name":"hypertriglyceridemia","score":0.9800000190734863},{"id":"https://openalex.org/keywords/hypercholesterolemia","display_name":"hypercholesterolemia","score":0.9980000257492065},{"id":"https://openalex.org/keywords/lipodystrophy","display_name":"lipodystrophy","score":0.7929999828338623},{"id":"https://openalex.org/keywords/insulin-resistance","display_name":"insulin resistance","score":0.878000020980835},{"id":"https://openalex.org/keywords/diabetes-mellitus","display_name":"diabetes mellitus","score":0.8500000238418579},{"id":"https://openalex.org/keywords/ritonavir","display_name":"ritonavir","score":0.8100000023841858},{"id":"https://openalex.org/keywords/coronary-artery-disease","display_name":"coronary artery disease","score":0.6919999718666077},{"id":"https://openalex.org/keywords/lipid-lowering-therapy","display_name":"lipid-lowering therapy","score":0.8690000176429749},{"id":"https://openalex.org/keywords/statins","display_name":"statins","score":0.9819999933242798},{"id":"https://openalex.org/keywords/fibrates","display_name":"fibrates","score":0.9959999918937683},{"id":"https://openalex.org/keywords/drug-interactions","display_name":"drug interactions","score":0.7870000004768372}],"concepts":[{"id":"https://openalex.org/C2779298103","wikidata":"https://www.wikidata.org/wiki/Q422618","display_name":"Ritonavir","level":5,"score":0.917984127998352},{"id":"https://openalex.org/C2780941825","wikidata":"https://www.wikidata.org/wiki/Q1538213","display_name":"Lipodystrophy","level":5,"score":0.7984786033630371},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.7542320489883423},{"id":"https://openalex.org/C2777182164","wikidata":"https://www.wikidata.org/wiki/Q422585","display_name":"Lopinavir","level":5,"score":0.6984740495681763},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.598578929901123},{"id":"https://openalex.org/C2777391703","wikidata":"https://www.wikidata.org/wiki/Q1053470","display_name":"Insulin resistance","level":3,"score":0.5571997165679932},{"id":"https://openalex.org/C2781413609","wikidata":"https://www.wikidata.org/wiki/Q7308373","display_name":"Regimen","level":2,"score":0.539423942565918},{"id":"https://openalex.org/C2776937687","wikidata":"https://www.wikidata.org/wiki/Q422654","display_name":"Saquinavir","level":5,"score":0.5166152119636536},{"id":"https://openalex.org/C2781143361","wikidata":"https://www.wikidata.org/wiki/Q55761529","display_name":"Protease inhibitor (pharmacology)","level":5,"score":0.5086916089057922},{"id":"https://openalex.org/C555293320","wikidata":"https://www.wikidata.org/wiki/Q12206","display_name":"Diabetes mellitus","level":2,"score":0.5007081031799316},{"id":"https://openalex.org/C2781392899","wikidata":"https://www.wikidata.org/wiki/Q422618","display_name":"Lopinavir/ritonavir","level":5,"score":0.4478887617588043},{"id":"https://openalex.org/C142462285","wikidata":"https://www.wikidata.org/wiki/Q2528140","display_name":"Viral load","level":3,"score":0.36206871271133423},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.31978195905685425},{"id":"https://openalex.org/C2993143319","wikidata":"https://www.wikidata.org/wiki/Q583050","display_name":"Antiretroviral therapy","level":4,"score":0.28130999207496643},{"id":"https://openalex.org/C2779306644","wikidata":"https://www.wikidata.org/wiki/Q2002370","display_name":"Insulin","level":2,"score":0.2702471613883972},{"id":"https://openalex.org/C3013748606","wikidata":"https://www.wikidata.org/wiki/Q15787","display_name":"Human immunodeficiency virus (HIV)","level":2,"score":0.24691370129585266},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.20174622535705566}],"mesh":[{"descriptor_ui":"D000960","descriptor_name":"Hypolipidemic Agents","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D000960","descriptor_name":"Hypolipidemic Agents","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D000960","descriptor_name":"Hypolipidemic Agents","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D002318","descriptor_name":"Cardiovascular Diseases","qualifier_ui":"Q000517","qualifier_name":"prevention & control","is_major_topic":false},{"descriptor_ui":"D002318","descriptor_name":"Cardiovascular Diseases","qualifier_ui":"Q000517","qualifier_name":"prevention & control","is_major_topic":false},{"descriptor_ui":"D002318","descriptor_name":"Cardiovascular Diseases","qualifier_ui":"Q000517","qualifier_name":"prevention & control","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006949","descriptor_name":"Hyperlipidemias","qualifier_ui":"Q000139","qualifier_name":"chemically induced","is_major_topic":false},{"descriptor_ui":"D006949","descriptor_name":"Hyperlipidemias","qualifier_ui":"Q000139","qualifier_name":"chemically induced","is_major_topic":false},{"descriptor_ui":"D006949","descriptor_name":"Hyperlipidemias","qualifier_ui":"Q000139","qualifier_name":"chemically induced","is_major_topic":false},{"descriptor_ui":"D006949","descriptor_name":"Hyperlipidemias","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":false},{"descriptor_ui":"D006949","descriptor_name":"Hyperlipidemias","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":false},{"descriptor_ui":"D006949","descriptor_name":"Hyperlipidemias","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":false},{"descriptor_ui":"D012307","descriptor_name":"Risk Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012307","descriptor_name":"Risk Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012307","descriptor_name":"Risk Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015658","descriptor_name":"HIV Infections","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":false},{"descriptor_ui":"D015658","descriptor_name":"HIV Infections","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":false},{"descriptor_ui":"D015658","descriptor_name":"HIV Infections","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":false},{"descriptor_ui":"D017320","descriptor_name":"HIV Protease Inhibitors","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":false},{"descriptor_ui":"D017320","descriptor_name":"HIV Protease Inhibitors","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":false},{"descriptor_ui":"D017320","descriptor_name":"HIV Protease Inhibitors","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":false},{"descriptor_ui":"D017320","descriptor_name":"HIV Protease Inhibitors","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":false},{"descriptor_ui":"D017320","descriptor_name":"HIV Protease Inhibitors","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":false},{"descriptor_ui":"D017320","descriptor_name":"HIV Protease Inhibitors","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":false},{"descriptor_ui":"D018752","descriptor_name":"Diet, Fat-Restricted","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018752","descriptor_name":"Diet, Fat-Restricted","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018752","descriptor_name":"Diet, Fat-Restricted","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D023241","descriptor_name":"Antiretroviral Therapy, Highly Active","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":false},{"descriptor_ui":"D023241","descriptor_name":"Antiretroviral Therapy, Highly Active","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":false},{"descriptor_ui":"D023241","descriptor_name":"Antiretroviral Therapy, Highly Active","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":false}],"locations_count":5,"locations":[{"id":"doi:10.1093/jac/dkh013","doi":"https://doi.org/10.1093/jac/dkh013","is_oa":true,"landing_page_url":"https://doi.org/10.1093/jac/dkh013","pdf_url":"https://academic.oup.com/jac/article-pdf/53/1/10/1985728/dkh013.pdf","source":{"id":"https://openalex.org/S124275759","display_name":"Journal of Antimicrobial Chemotherapy","issn_l":"0305-7453","issn":["0305-7453","1460-2091"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Antimicrobial Chemotherapy","raw_type":"journal-article"},{"id":"pmid:14645323","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/14645323","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of antimicrobial chemotherapy","raw_type":"Journal Article"},{"id":"pmh:oai:cris.unibo.it:11585/17215","doi":null,"is_oa":false,"landing_page_url":"http://hdl.handle.net/11585/17215","pdf_url":null,"source":{"id":"https://openalex.org/S4306402579","display_name":"Archivio istituzionale della ricerca (Alma Mater Studiorum Universit\u00e0 di Bologna)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4210117483","host_organization_name":"Istituto di Ematologia di Bologna","host_organization_lineage":["https://openalex.org/I4210117483"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:open-archive.highwire.org:jac:dkh013v1","doi":null,"is_oa":false,"landing_page_url":"http://jac.oxfordjournals.org/cgi/content/short/dkh013v1","pdf_url":null,"source":{"id":"https://openalex.org/S4406923041","display_name":"HighWire Press Open Archive","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"TEXT"},{"id":"pmh:oai:zenodo.org:148130","doi":null,"is_oa":true,"landing_page_url":"https://www.openaccessrepository.it/record/148130","pdf_url":null,"source":{"id":"https://openalex.org/S4306402478","display_name":"INFM-OAR (INFN Catania)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4210116497","host_organization_name":"Istituto Nazionale di Fisica Nucleare, Sezione di Catania","host_organization_lineage":["https://openalex.org/I4210116497"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":{"id":"doi:10.1093/jac/dkh013","doi":"https://doi.org/10.1093/jac/dkh013","is_oa":true,"landing_page_url":"https://doi.org/10.1093/jac/dkh013","pdf_url":"https://academic.oup.com/jac/article-pdf/53/1/10/1985728/dkh013.pdf","source":{"id":"https://openalex.org/S124275759","display_name":"Journal of Antimicrobial Chemotherapy","issn_l":"0305-7453","issn":["0305-7453","1460-2091"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Antimicrobial Chemotherapy","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":1.0}],"sustainable_development_goals_aurora":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.8799999952316284}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2136162563.pdf","grobid_xml":"https://content.openalex.org/works/W2136162563.grobid-xml"},"referenced_works_count":32,"referenced_works":["https://openalex.org/W197130036","https://openalex.org/W1964510458","https://openalex.org/W1967025750","https://openalex.org/W1974612571","https://openalex.org/W1978444406","https://openalex.org/W1979192842","https://openalex.org/W1979252165","https://openalex.org/W1988400413","https://openalex.org/W1991485152","https://openalex.org/W1993508860","https://openalex.org/W1998125635","https://openalex.org/W2002615726","https://openalex.org/W2010352983","https://openalex.org/W2015990374","https://openalex.org/W2019269810","https://openalex.org/W2020329044","https://openalex.org/W2021967791","https://openalex.org/W2033756224","https://openalex.org/W2053382469","https://openalex.org/W2054444007","https://openalex.org/W2063076247","https://openalex.org/W2082508521","https://openalex.org/W2088643134","https://openalex.org/W2101105570","https://openalex.org/W2113643689","https://openalex.org/W2122384381","https://openalex.org/W2125352492","https://openalex.org/W2127175348","https://openalex.org/W2136385005","https://openalex.org/W2150961630","https://openalex.org/W2332883209","https://openalex.org/W2339057709"],"related_works":["https://openalex.org/W1984010627","https://openalex.org/W2055228745","https://openalex.org/W2051976738","https://openalex.org/W2611234483","https://openalex.org/W2108000358","https://openalex.org/W2113921871","https://openalex.org/W2021127040","https://openalex.org/W2101251098","https://openalex.org/W1986196348","https://openalex.org/W2317464954"],"abstract_inverted_index":{"Highly":[0],"active":[1],"antiretroviral":[2,61,167],"therapy":[3,146],"(HAART)":[4],"has":[5,120],"had":[6],"a":[7,22,137],"significant":[8],"impact":[9],"on":[10,143],"the":[11,82],"natural":[12],"history":[13],"of":[14,71,104,115,156],"human":[15],"immunodeficiency":[16],"virus":[17],"(HIV)":[18],"infection,":[19],"leading":[20],"to":[21,69,88,136],"remarkable":[23],"decrease":[24],"in":[25,54,67,92,123],"its":[26],"morbidity":[27],"and":[28,36,47,76,134],"mortality,":[29],"but":[30,111],"is":[31,147],"frequently":[32],"associated":[33,79],"with":[34,57,80,95,150,166],"clinical":[35],"metabolic":[37],"complications.":[38],"Fat":[39],"redistribution":[40],"or":[41,98,152],"lipodystrophy,":[42],"hypertriglyceridaemia,":[43],"hypercholesterolaemia,":[44],"insulin":[45],"resistance":[46],"diabetes":[48],"mellitus":[49],"have":[50],"been":[51,121],"extensively":[52],"reported":[53,122],"subjects":[55],"treated":[56,94],"protease":[58],"inhibitor":[59],"(PI)-based":[60],"regimens.":[62],"In":[63],"particular,":[64],"dyslipidaemia":[65],"occurs":[66],"up":[68],"70-80%":[70],"HIV-infected":[72],"individuals":[73],"receiving":[74,127],"HAART":[75],"can":[77],"be":[78,89],"all":[81],"available":[83],"PIs,":[84],"although":[85],"hypertriglyceridaemia":[86],"appears":[87],"more":[90],"frequent":[91],"patients":[93],"ritonavir,":[96],"ritonavir-saquinavir,":[97],"ritonavir-lopinavir.":[99],"The":[100,154],"potential":[101,163],"long-term":[102],"consequences":[103],"HAART-associated":[105],"hyperlipidaemia":[106],"are":[107],"not":[108],"completely":[109],"understood,":[110],"an":[112],"increased":[113],"risk":[114],"premature":[116],"coronary":[117],"artery":[118],"disease":[119],"young":[124],"HIV-positive":[125],"persons":[126],"PIs.":[128],"Dietary":[129],"changes,":[130],"regular":[131],"aerobic":[132],"exercise":[133],"switching":[135],"PI-sparing":[138],"regimen":[139],"may":[140],"act":[141],"favourably":[142],"dyslipidaemia.":[144],"Lipid-lowering":[145],"often":[148],"required":[149],"statins":[151],"fibrates.":[153],"choice":[155],"hypolipidaemic":[157],"drugs":[158],"should":[159],"take":[160],"into":[161],"account":[162],"pharmacological":[164],"interactions":[165],"agents.":[168]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2024,"cited_by_count":6},{"year":2023,"cited_by_count":2},{"year":2022,"cited_by_count":4},{"year":2021,"cited_by_count":5},{"year":2020,"cited_by_count":2},{"year":2019,"cited_by_count":2},{"year":2018,"cited_by_count":7},{"year":2017,"cited_by_count":3},{"year":2016,"cited_by_count":10},{"year":2015,"cited_by_count":7},{"year":2014,"cited_by_count":16},{"year":2013,"cited_by_count":14},{"year":2012,"cited_by_count":8}],"updated_date":"2026-10-12T09:40:04.860316","created_date":"2025-10-10T00:00:00"}