{"id":"https://openalex.org/W2135893210","doi":"https://doi.org/10.1093/bja/aem173","title":"Changes in a surgical stress index in response to standardized pain stimuli during propofol\u2013remifentanil infusion","display_name":"Changes in a surgical stress index in response to standardized pain stimuli during propofol\u2013remifentanil infusion","publication_year":2007,"publication_date":"2007-07-03","ids":{"openalex":"https://openalex.org/W2135893210","doi":"https://doi.org/10.1093/bja/aem173","mag":"2135893210","pmid":"https://pubmed.ncbi.nlm.nih.gov/17609248"},"language":"en","primary_location":{"id":"doi:10.1093/bja/aem173","doi":"https://doi.org/10.1093/bja/aem173","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bja/aem173","pdf_url":"http://bjanaesthesia.org/article/S0007091217347232/pdf","source":{"id":"https://openalex.org/S33418846","display_name":"British Journal of Anaesthesia","issn_l":"0007-0912","issn":["0007-0912","1471-6771"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"British Journal of Anaesthesia","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"http://bjanaesthesia.org/article/S0007091217347232/pdf","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5048910956","display_name":"Michel M. R. F. Struys","orcid":"https://orcid.org/0000-0003-0421-536X","observed_orcids":["https://orcid.org/0000-0003-0421-536X"]},"institutions":[{"id":"https://openalex.org/I2801227569","display_name":"Ghent University Hospital","ror":"https://ror.org/00xmkp704","country_code":"BE","type":"healthcare","lineage":["https://openalex.org/I2801227569"]}],"countries":["BE"],"is_corresponding":true,"raw_author_name":"M.M.R.F. Struys","raw_affiliation_strings":["Department of Anaesthesia, Ghent University Hospital, De Pintelaan 185, B-9000 Ghent, Belgium. michel.struys@ugent.be","Department of Anaesthesia, Ghent University Hospital, De Pintelaan 185, b-9000, Ghent, Belgium"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Anaesthesia, Ghent University Hospital, De Pintelaan 185, B-9000 Ghent, Belgium. michel.struys@ugent.be","institution_ids":["https://openalex.org/I2801227569"]},{"raw_affiliation_string":"Department of Anaesthesia, Ghent University Hospital, De Pintelaan 185, b-9000, Ghent, Belgium","institution_ids":["https://openalex.org/I2801227569"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5062289826","display_name":"Caroline M. Vanpeteghem","orcid":"https://orcid.org/0000-0002-8843-959X","observed_orcids":["https://orcid.org/0000-0002-8843-959X"]},"institutions":[{"id":"https://openalex.org/I2801227569","display_name":"Ghent University Hospital","ror":"https://ror.org/00xmkp704","country_code":"BE","type":"healthcare","lineage":["https://openalex.org/I2801227569"]}],"countries":["BE"],"is_corresponding":false,"raw_author_name":"C. Vanpeteghem","raw_affiliation_strings":["Department of Anaesthesia, Ghent University Hospital, De Pintelaan 185, b-9000, Ghent, Belgium"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Anaesthesia, Ghent University Hospital, De Pintelaan 185, b-9000, Ghent, Belgium","institution_ids":["https://openalex.org/I2801227569"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5062219429","display_name":"M. Huiku","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210137361","display_name":"General Electric (Finland)","ror":"https://ror.org/04h6zzz03","country_code":"FI","type":"company","lineage":["https://openalex.org/I1332737386","https://openalex.org/I4210137361"]}],"countries":["FI"],"is_corresponding":false,"raw_author_name":"M. Huiku","raw_affiliation_strings":["GE Healthcare Finland Oy, Helsinki, Finland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"GE Healthcare Finland Oy, Helsinki, Finland","institution_ids":["https://openalex.org/I4210137361"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5060511395","display_name":"K. Uutela","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210137361","display_name":"General Electric (Finland)","ror":"https://ror.org/04h6zzz03","country_code":"FI","type":"company","lineage":["https://openalex.org/I1332737386","https://openalex.org/I4210137361"]}],"countries":["FI"],"is_corresponding":false,"raw_author_name":"K. Uutela","raw_affiliation_strings":["GE Healthcare Finland Oy, Helsinki, Finland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"GE Healthcare Finland Oy, Helsinki, Finland","institution_ids":["https://openalex.org/I4210137361"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5058986232","display_name":"N.B.K. Blyaert","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2801227569","display_name":"Ghent University Hospital","ror":"https://ror.org/00xmkp704","country_code":"BE","type":"healthcare","lineage":["https://openalex.org/I2801227569"]}],"countries":["BE"],"is_corresponding":false,"raw_author_name":"N.B.K. Blyaert","raw_affiliation_strings":["Department of Anaesthesia, Ghent University Hospital, De Pintelaan 185, b-9000, Ghent, Belgium"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Anaesthesia, Ghent University Hospital, De Pintelaan 185, b-9000, Ghent, Belgium","institution_ids":["https://openalex.org/I2801227569"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5032070082","display_name":"Eric P. Mortier","orcid":"https://orcid.org/0000-0003-3144-5929","observed_orcids":["https://orcid.org/0000-0003-3144-5929","https://orcid.org/0000-0001-9786-0143"]},"institutions":[{"id":"https://openalex.org/I2801227569","display_name":"Ghent University Hospital","ror":"https://ror.org/00xmkp704","country_code":"BE","type":"healthcare","lineage":["https://openalex.org/I2801227569"]}],"countries":["BE"],"is_corresponding":false,"raw_author_name":"E.P. Mortier","raw_affiliation_strings":["Department of Anaesthesia, Ghent University Hospital, De Pintelaan 185, b-9000, Ghent, Belgium"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Anaesthesia, Ghent University Hospital, De Pintelaan 185, b-9000, Ghent, Belgium","institution_ids":["https://openalex.org/I2801227569"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5048910956"],"corresponding_institution_ids":["https://openalex.org/I2801227569"],"apc_list":{"value":4450,"currency":"USD","value_usd":4450},"apc_paid":null,"fwci":11.207,"has_fulltext":true,"cited_by_count":156,"citation_normalized_percentile":{"value":0.98720309,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":96,"max":99},"biblio":{"volume":"99","issue":"3","first_page":"359","last_page":"367"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10436","display_name":"Anesthesia and Sedative Agents","score":0.9907000064849854,"subfield":{"id":"https://openalex.org/subfields/2703","display_name":"Anesthesiology and Pain Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10436","display_name":"Anesthesia and Sedative Agents","score":0.9907000064849854,"subfield":{"id":"https://openalex.org/subfields/2703","display_name":"Anesthesiology and Pain Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10189","display_name":"Anesthesia and Pain Management","score":0.0038999998942017555,"subfield":{"id":"https://openalex.org/subfields/2703","display_name":"Anesthesiology and Pain Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11905","display_name":"Veterinary Pharmacology and Anesthesia","score":0.002199999988079071,"subfield":{"id":"https://openalex.org/subfields/3404","display_name":"Small Animals"},"field":{"id":"https://openalex.org/fields/34","display_name":"Veterinary"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/propofol","display_name":"propofol","score":0.8209999799728394},{"id":"https://openalex.org/keywords/remifentanil","display_name":"remifentanil","score":1.0},{"id":"https://openalex.org/keywords/target-controlled-infusion","display_name":"target-controlled infusion","score":0.7269999980926514},{"id":"https://openalex.org/keywords/response-entropy","display_name":"response entropy","score":0.5680000185966492},{"id":"https://openalex.org/keywords/state-entropy","display_name":"state entropy","score":0.8669999837875366},{"id":"https://openalex.org/keywords/photoplethysmography","display_name":"photoplethysmography","score":0.8529999852180481},{"id":"https://openalex.org/keywords/pulse-wave-amplitude","display_name":"pulse wave amplitude","score":0.8740000128746033},{"id":"https://openalex.org/keywords/heart-rate","display_name":"heart rate","score":0.8529999852180481},{"id":"https://openalex.org/keywords/noxious-stimuli","display_name":"noxious stimuli","score":0.6729999780654907},{"id":"https://openalex.org/keywords/depth-of-sedation","display_name":"sedation depth","score":0.382999986410141}],"concepts":[{"id":"https://openalex.org/C2778891214","wikidata":"https://www.wikidata.org/wiki/Q417902","display_name":"Remifentanil","level":3,"score":0.8058719635009766},{"id":"https://openalex.org/C15490471","wikidata":"https://www.wikidata.org/wiki/Q2734305","display_name":"Nociception","level":3,"score":0.7561172246932983},{"id":"https://openalex.org/C2776277131","wikidata":"https://www.wikidata.org/wiki/Q422740","display_name":"Propofol","level":2,"score":0.7171615958213806},{"id":"https://openalex.org/C42219234","wikidata":"https://www.wikidata.org/wiki/Q131130","display_name":"Anesthesia","level":1,"score":0.710914134979248},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.6673771739006042},{"id":"https://openalex.org/C104211972","wikidata":"https://www.wikidata.org/wiki/Q7067309","display_name":"Noxious stimulus","level":4,"score":0.6378570795059204},{"id":"https://openalex.org/C2777953023","wikidata":"https://www.wikidata.org/wiki/Q1073121","display_name":"Heart rate","level":3,"score":0.5451688766479492},{"id":"https://openalex.org/C2779918689","wikidata":"https://www.wikidata.org/wiki/Q3771842","display_name":"Stimulus (psychology)","level":2,"score":0.43099167943000793},{"id":"https://openalex.org/C84393581","wikidata":"https://www.wikidata.org/wiki/Q82642","display_name":"Blood pressure","level":2,"score":0.21363773941993713},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.19840753078460693},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.12477648258209229},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.0},{"id":"https://openalex.org/C542102704","wikidata":"https://www.wikidata.org/wiki/Q183257","display_name":"Psychotherapist","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000077208","descriptor_name":"Remifentanil","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000293","descriptor_name":"Adolescent","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000701","descriptor_name":"Analgesics, Opioid","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":false},{"descriptor_ui":"D000701","descriptor_name":"Analgesics, Opioid","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D004334","descriptor_name":"Drug Administration Schedule","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004569","descriptor_name":"Electroencephalography","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006339","descriptor_name":"Heart Rate","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010147","descriptor_name":"Pain Measurement","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D010880","descriptor_name":"Piperidines","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":false},{"descriptor_ui":"D010880","descriptor_name":"Piperidines","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D012815","descriptor_name":"Signal Processing, Computer-Assisted","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013312","descriptor_name":"Stress, Physiological","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":false},{"descriptor_ui":"D013312","descriptor_name":"Stress, Physiological","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":true},{"descriptor_ui":"D013312","descriptor_name":"Stress, Physiological","qualifier_ui":"Q000517","qualifier_name":"prevention & control","is_major_topic":false},{"descriptor_ui":"D015742","descriptor_name":"Propofol","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":false},{"descriptor_ui":"D015742","descriptor_name":"Propofol","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D016343","descriptor_name":"Monitoring, Intraoperative","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D017156","descriptor_name":"Photoplethysmography","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019277","descriptor_name":"Entropy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1093/bja/aem173","doi":"https://doi.org/10.1093/bja/aem173","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bja/aem173","pdf_url":"http://bjanaesthesia.org/article/S0007091217347232/pdf","source":{"id":"https://openalex.org/S33418846","display_name":"British Journal of Anaesthesia","issn_l":"0007-0912","issn":["0007-0912","1471-6771"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"British Journal of Anaesthesia","raw_type":"journal-article"},{"id":"pmid:17609248","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/17609248","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"British journal of anaesthesia","raw_type":"Journal Article"},{"id":"pmh:oai:archive.ugent.be:390962","doi":null,"is_oa":false,"landing_page_url":"https://biblio.ugent.be/publication/390962","pdf_url":null,"source":{"id":"https://openalex.org/S4306400478","display_name":"Ghent University Academic Bibliography (Ghent University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I32597200","host_organization_name":"Ghent University","host_organization_lineage":["https://openalex.org/I32597200"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"ISSN: 1471-6771","raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":{"id":"doi:10.1093/bja/aem173","doi":"https://doi.org/10.1093/bja/aem173","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bja/aem173","pdf_url":"http://bjanaesthesia.org/article/S0007091217347232/pdf","source":{"id":"https://openalex.org/S33418846","display_name":"British Journal of Anaesthesia","issn_l":"0007-0912","issn":["0007-0912","1471-6771"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"British Journal of Anaesthesia","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.9763000011444092,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320321910","display_name":"Universitair Ziekenhuis Gent","ror":"https://ror.org/00xmkp704"},{"id":"https://openalex.org/F4320322603","display_name":"Universiteit Gent","ror":"https://ror.org/00cv9y106"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2135893210.pdf","grobid_xml":"https://content.openalex.org/works/W2135893210.grobid-xml"},"referenced_works_count":35,"referenced_works":["https://openalex.org/W1965614042","https://openalex.org/W1973373700","https://openalex.org/W1974488368","https://openalex.org/W1980693414","https://openalex.org/W1981651633","https://openalex.org/W1983146379","https://openalex.org/W1986621959","https://openalex.org/W1986966459","https://openalex.org/W1994633745","https://openalex.org/W2024687868","https://openalex.org/W2028898118","https://openalex.org/W2032029144","https://openalex.org/W2072945503","https://openalex.org/W2084444573","https://openalex.org/W2086114942","https://openalex.org/W2089906970","https://openalex.org/W2094698508","https://openalex.org/W2096993177","https://openalex.org/W2103782019","https://openalex.org/W2104377364","https://openalex.org/W2109653290","https://openalex.org/W2112101180","https://openalex.org/W2115473091","https://openalex.org/W2120534719","https://openalex.org/W2122171313","https://openalex.org/W2126260437","https://openalex.org/W2141785961","https://openalex.org/W2143815568","https://openalex.org/W2145996826","https://openalex.org/W2146324364","https://openalex.org/W2159733957","https://openalex.org/W2167021426","https://openalex.org/W2167562588","https://openalex.org/W2171894199","https://openalex.org/W2321018128"],"related_works":["https://openalex.org/W2145996826","https://openalex.org/W4410787551","https://openalex.org/W2148599159","https://openalex.org/W2317187852","https://openalex.org/W6999439745","https://openalex.org/W2137139861","https://openalex.org/W2138815770","https://openalex.org/W2398301721","https://openalex.org/W2377883258","https://openalex.org/W7064712315"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":3},{"year":2025,"cited_by_count":10},{"year":2024,"cited_by_count":6},{"year":2023,"cited_by_count":11},{"year":2022,"cited_by_count":8},{"year":2021,"cited_by_count":6},{"year":2020,"cited_by_count":6},{"year":2019,"cited_by_count":10},{"year":2018,"cited_by_count":9},{"year":2017,"cited_by_count":12},{"year":2016,"cited_by_count":8},{"year":2015,"cited_by_count":6},{"year":2014,"cited_by_count":9},{"year":2013,"cited_by_count":8},{"year":2012,"cited_by_count":12}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2016-06-24T00:00:00"}