{"id":"https://openalex.org/W2135649690","doi":null,"title":"A Three-Dimensional Bidirectional Interface for Neural Mapping Studies","display_name":"A Three-Dimensional Bidirectional Interface for Neural Mapping Studies","publication_year":2010,"publication_date":"2010-01-01","ids":{"openalex":"https://openalex.org/W2135649690","mag":"2135649690"},"language":"en","primary_location":{"id":"pmh:oai:deepblue.lib.umich.edu:2027.42/77831","doi":null,"is_oa":false,"landing_page_url":"https://hdl.handle.net/2027.42/77831","pdf_url":null,"source":{"id":"https://openalex.org/S4306400393","display_name":"Deep Blue (University of Michigan)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I27837315","host_organization_name":"University of Michigan","host_organization_lineage":["https://openalex.org/I27837315"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Thesis"},"volume":null,"type":"dissertation","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5029381186","display_name":"Mary Elizabeth Merriam","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Mary Elizabeth Merriam","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":["https://openalex.org/A5029381186"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":9,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11601","display_name":"Neuroscience and Neural Engineering","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11601","display_name":"Neuroscience and Neural Engineering","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10323","display_name":"Analog and Mixed-Signal Circuit Design","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2208","display_name":"Electrical and Electronic Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T14411","display_name":"Undergraduate Neuroscience Education and Research","score":0.0,"subfield":{"id":"https://openalex.org/subfields/3304","display_name":"Education"},"field":{"id":"https://openalex.org/fields/33","display_name":"Social Sciences"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/neural-recording","display_name":"neural recording","score":0.5059999823570251},{"id":"https://openalex.org/keywords/neurostimulation","display_name":"neurostimulation","score":0.8360000252723694},{"id":"https://openalex.org/keywords/carbon-nanotubes","display_name":"carbon nanotubes","score":0.722000002861023},{"id":"https://openalex.org/keywords/iridium-electrodes","display_name":"iridium electrodes","score":0.7149999737739563},{"id":"https://openalex.org/keywords/neural-amplifier","display_name":"neural amplifier","score":0.5690000057220459},{"id":"https://openalex.org/keywords/electrode-tissue-interface","display_name":"electrode-tissue interface","score":0.6610000133514404},{"id":"https://openalex.org/keywords/chronic-implantation","display_name":"chronic implantation","score":0.5370000004768372},{"id":"https://openalex.org/keywords/somatosensory-integration","display_name":"somatosensory integration","score":0.6499999761581421},{"id":"https://openalex.org/keywords/prostheses","display_name":"prosthesis","score":0.5740000009536743},{"id":"https://openalex.org/keywords/boron-doped-silicon","display_name":"boron-doped silicon","score":0.6359999775886536}],"concepts":[{"id":"https://openalex.org/C113843644","wikidata":"https://www.wikidata.org/wiki/Q901882","display_name":"Interface (matter)","level":4,"score":0.5374276041984558},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.5182492733001709},{"id":"https://openalex.org/C107457646","wikidata":"https://www.wikidata.org/wiki/Q207434","display_name":"Human\u2013computer interaction","level":1,"score":0.3576398491859436},{"id":"https://openalex.org/C111919701","wikidata":"https://www.wikidata.org/wiki/Q9135","display_name":"Operating system","level":1,"score":0.06507784128189087},{"id":"https://openalex.org/C129307140","wikidata":"https://www.wikidata.org/wiki/Q6795880","display_name":"Maximum bubble pressure method","level":3,"score":0.0},{"id":"https://openalex.org/C157915830","wikidata":"https://www.wikidata.org/wiki/Q2928001","display_name":"Bubble","level":2,"score":0.0}],"mesh":[],"locations_count":2,"locations":[{"id":"pmh:oai:deepblue.lib.umich.edu:2027.42/77831","doi":null,"is_oa":false,"landing_page_url":"https://hdl.handle.net/2027.42/77831","pdf_url":null,"source":{"id":"https://openalex.org/S4306400393","display_name":"Deep Blue (University of Michigan)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I27837315","host_organization_name":"University of Michigan","host_organization_lineage":["https://openalex.org/I27837315"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Thesis"},{"id":"mag:2135649690","doi":null,"is_oa":false,"landing_page_url":"https://deepblue.lib.umich.edu/handle/2027.42/77831","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2111887426","https://openalex.org/W2102331052","https://openalex.org/W2618944530","https://openalex.org/W2117130579","https://openalex.org/W2573347855","https://openalex.org/W2129028141","https://openalex.org/W1509175867","https://openalex.org/W2161272185","https://openalex.org/W7098394493","https://openalex.org/W3119448270"],"abstract_inverted_index":{"Advances":[0],"in":[1,47,95,199,280,298,323],"neuro-medicine":[2],"depend":[3],"critically":[4],"on":[5,33,37,42,176],"supporting":[6],"technologies,":[7],"including":[8],"those":[9],"associated":[10],"with":[11,70,155,273,304,337],"penetrating":[12],"microelectrodes.":[13],"While":[14],"these":[15],"have":[16,83,98],"developed":[17],"from":[18,120],"single-site":[19],"microwires":[20],"to":[21,73,122],"three-dimensional":[22,54],"micromachined":[23],"electrode":[24,39],"systems,":[25],"several":[26],"important":[27],"issues":[28],"remain.":[29],"This":[30,143],"research":[31],"focused":[32],"the":[34,86,106,112,139,145,158,167,177,188,195,212,233,245,253,257],"array-tissue":[35],"interface,":[36],"application-specific":[38],"design,":[40],"and":[41,109,161,170,190,214,228,240,261,288,321,343],"neural":[43,311],"amplifiers":[44],"for":[45,78,127,151,208,232,251],"use":[46],"bidirectional":[48],"microelectrode":[49],"system":[50,260],"front-ends.":[51],"Three":[52],"new":[53,309],"array":[55,207],"structures":[56],"were":[57,271,302],"developed.":[58],"A":[59,205,308],"novel":[60],"architecture,":[61],"which":[62],"enables":[63],"two":[64],"perpendicular":[65],"probe":[66],"sets,":[67],"was":[68,132,286,319],"coupled":[69],"open-scaffold":[71],"shanks":[72],"create":[74],"3-D":[75,130,225],"lattice":[76,102],"arrays":[77,82,131,250],"bio-response":[79],"investigations.":[80],"These":[81],"15%":[84],"of":[85,89,114,194,211,219,247,256,283,317,335,348],"shank":[87,171],"area":[88],"constant-footprint":[90],"solid":[91],"counterparts.":[92],"Chronic":[93],"(8-week)":[94],"vivo":[96],"studies":[97,231],"shown":[99],"similar":[100],"2-D":[101],"probes":[103],"significantly":[104],"mitigated":[105],"tissue":[107],"reaction":[108],"dramatically":[110],"increased":[111],"number":[113],"adjacent":[115],"(within":[116],"50\u03bcm)":[117],"surviving":[118],"neurons":[119],"36%":[121],"87%.":[123],"An":[124],"innovative":[125],"design":[126],"rapidly-assembled":[128],"folded":[129],"created,":[133],"requiring":[134],"only":[135,192,315],"one":[136],"mask":[137],"beyond":[138],"standard":[140],"boron-doped":[141],"process.":[142,327],"realizes":[144],"smallest":[146],"platform":[147,159],"structure":[148],"ever":[149],"reported":[150],"such":[152],"a":[153,324,338],"device,":[154],"zero-rise":[156],"above":[157,187],"top":[160],"virtually":[162],"no":[163],"lateral":[164],"extent":[165],"past":[166],"probes.":[168],"Electrode":[169],"pitch":[172],"are":[173],"both":[174],"200\u03bcm":[175],"64-site":[178],"prototype.":[179],"The":[180,328],"implanted":[181],"device":[182],"stands":[183],"less":[184],"than":[185],"350\u03bcm":[186],"cortex":[189,202,301],"displaces":[191],"1.7%":[193],"instrumented":[196],"area.":[197],"Recordings":[198],"guinea":[200,299],"pig":[201,300],"verified":[203],"functionality.":[204],"160-site":[206],"neuroscience":[209],"mapping":[210,227],"ventral":[213],"dorsal":[215],"cochlear":[216],"nucleus":[217],"consisting":[218],"five-probes":[220],"(3-VCN,":[221],"2-DCN)":[222],"permitted":[223],"high-density":[224],"CN":[226],"somatosensory":[229],"integration":[230],"first":[234],"time.":[235],"Multi-region":[236],"stimulation":[237],"(1000\u03bcm2":[238],"sites)":[239,243],"recording":[241,312],"(177\u03bcm2":[242],"demonstrated":[244],"efficacy":[246],"bimodal":[248],"silicon":[249],"investigating":[252],"biological":[254],"circuits":[255],"central":[258],"nervous":[259],"as":[262],"prosthetic":[263],"devices.":[264],"For":[265],"electrode-electrolyte":[266],"interface":[267],"enhancement,":[268],"iridium":[269],"sites":[270,290],"modified":[272],"carbon":[274],"nanotubes":[275],"(CNTs).":[276],"On":[277],"non-released":[278],"probes,":[279],"situ":[281],"growth":[282],"vertically-aligned":[284],"forests":[285],"achieved,":[287],"dip-coated":[289,306],"exhibited":[291],"an":[292,332,344],"order-of-magnitude":[293],"impedance":[294],"reduction.":[295],"Neural":[296],"signals":[297],"recorded":[303],"released":[305],"CNT-probes.":[307],"integrated":[310],"amplifier,":[313],"consuming":[314],"46.5\u03bcW":[316],"power,":[318],"designed":[320],"fabricated":[322],"0.5\u03bcm":[325],"CMOS":[326],"0.026mm2":[329],"circuit":[330],"has":[331],"in-band":[333],"gain":[334],"58.9dB":[336],"tunable":[339],"lower":[340],"cutoff":[341,346],"frequency":[342,347],"upper":[345],"21.3kHz.":[349]},"counts_by_year":[{"year":2017,"cited_by_count":1},{"year":2015,"cited_by_count":1},{"year":2014,"cited_by_count":1},{"year":2013,"cited_by_count":2},{"year":2012,"cited_by_count":1}],"updated_date":"2026-08-08T01:25:22.217667","created_date":"2016-06-24T00:00:00"}