{"id":"https://openalex.org/W2135447402","doi":"https://doi.org/10.1242/dev.119768","title":"Neuromesodermal progenitors and the making of the spinal cord","display_name":"Neuromesodermal progenitors and the making of the spinal cord","publication_year":2015,"publication_date":"2015-09-01","ids":{"openalex":"https://openalex.org/W2135447402","doi":"https://doi.org/10.1242/dev.119768","mag":"2135447402","pmid":"https://pubmed.ncbi.nlm.nih.gov/26329597","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/4958456"},"language":"en","primary_location":{"id":"doi:10.1242/dev.119768","doi":"https://doi.org/10.1242/dev.119768","is_oa":true,"landing_page_url":"https://doi.org/10.1242/dev.119768","pdf_url":"https://dev.biologists.org/content/develop/142/17/2864.full.pdf","source":{"id":"https://openalex.org/S86558740","display_name":"Development","issn_l":"0950-1991","issn":["0950-1991","1477-9129"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311847","host_organization_name":"The Company of Biologists","host_organization_lineage":["https://openalex.org/P4310311847"],"host_organization_lineage_names":["The Company of Biologists"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Development","raw_type":"journal-article"},"volume":null,"type":"review","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://dev.biologists.org/content/develop/142/17/2864.full.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5077255106","display_name":"Domingos Henrique","orcid":"https://orcid.org/0000-0001-8869-1894","observed_orcids":["https://orcid.org/0000-0001-8869-1894"]},"institutions":[{"id":"https://openalex.org/I141596103","display_name":"University of Lisbon","ror":"https://ror.org/01c27hj86","country_code":"PT","type":"education","lineage":["https://openalex.org/I141596103"]},{"id":"https://openalex.org/I4392738257","display_name":"Instituto de Medicina Molecular Jo\u00e3o Lobo Antunes","ror":"https://ror.org/019g8w217","country_code":"PT","type":"facility","lineage":["https://openalex.org/I141596103","https://openalex.org/I4392738257","https://openalex.org/I4405252639"]},{"id":"https://openalex.org/I4405260141","display_name":"Instituto de Histologia e Biologia do Desenvolvimento","ror":"https://ror.org/03actwe44","country_code":"PT","type":"education","lineage":["https://openalex.org/I141596103","https://openalex.org/I4405260141"]}],"countries":["PT"],"is_corresponding":false,"raw_author_name":"Domingos Henrique","raw_affiliation_strings":["Instituto de Medicina Molecular and Instituto de Histologia e Biologia do Desenvolvimento, Faculdade de Medicina da Universidade de Lisboa, Avenida Prof. Egas Moniz, Lisboa 1649-028, Portugal"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Instituto de Medicina Molecular and Instituto de Histologia e Biologia do Desenvolvimento, Faculdade de Medicina da Universidade de Lisboa, Avenida Prof. Egas Moniz, Lisboa 1649-028, Portugal","institution_ids":["https://openalex.org/I141596103","https://openalex.org/I4392738257","https://openalex.org/I4405260141"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5076163780","display_name":"Elsa Abranches","orcid":"https://orcid.org/0000-0003-4493-6065","observed_orcids":["https://orcid.org/0000-0003-4493-6065"]},"institutions":[{"id":"https://openalex.org/I141596103","display_name":"University of Lisbon","ror":"https://ror.org/01c27hj86","country_code":"PT","type":"education","lineage":["https://openalex.org/I141596103"]},{"id":"https://openalex.org/I4392738257","display_name":"Instituto de Medicina Molecular Jo\u00e3o Lobo Antunes","ror":"https://ror.org/019g8w217","country_code":"PT","type":"facility","lineage":["https://openalex.org/I141596103","https://openalex.org/I4392738257","https://openalex.org/I4405252639"]},{"id":"https://openalex.org/I4405260141","display_name":"Instituto de Histologia e Biologia do Desenvolvimento","ror":"https://ror.org/03actwe44","country_code":"PT","type":"education","lineage":["https://openalex.org/I141596103","https://openalex.org/I4405260141"]}],"countries":["PT"],"is_corresponding":false,"raw_author_name":"Elsa Abranches","raw_affiliation_strings":["Instituto de Medicina Molecular and Instituto de Histologia e Biologia do Desenvolvimento, Faculdade de Medicina da Universidade de Lisboa, Avenida Prof. Egas Moniz, Lisboa 1649-028, Portugal"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Instituto de Medicina Molecular and Instituto de Histologia e Biologia do Desenvolvimento, Faculdade de Medicina da Universidade de Lisboa, Avenida Prof. Egas Moniz, Lisboa 1649-028, Portugal","institution_ids":["https://openalex.org/I141596103","https://openalex.org/I4392738257","https://openalex.org/I4405260141"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5064114705","display_name":"Laure Verrier","orcid":"https://orcid.org/0000-0003-2808-8780","observed_orcids":["https://orcid.org/0000-0003-2808-8780"]},"institutions":[{"id":"https://openalex.org/I177639307","display_name":"University of Dundee","ror":"https://ror.org/03h2bxq36","country_code":"GB","type":"education","lineage":["https://openalex.org/I177639307"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Laure Verrier","raw_affiliation_strings":["Division of Cell & Developmental Biology, College of Life Sciences, University of Dundee, Dow Street, Dundee DD1 5EH, UK","Division of Cell and Developmental Biology, College of Life Sciences, University of Dundee, Dow Street, Dundee DD1 5EH, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Cell & Developmental Biology, College of Life Sciences, University of Dundee, Dow Street, Dundee DD1 5EH, UK","institution_ids":["https://openalex.org/I177639307"]},{"raw_affiliation_string":"Division of Cell and Developmental Biology, College of Life Sciences, University of Dundee, Dow Street, Dundee DD1 5EH, UK","institution_ids":["https://openalex.org/I177639307"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5000988484","display_name":"Kate G. Storey","orcid":"https://orcid.org/0000-0003-3506-1287","observed_orcids":["https://orcid.org/0000-0003-3506-1287"]},"institutions":[{"id":"https://openalex.org/I177639307","display_name":"University of Dundee","ror":"https://ror.org/03h2bxq36","country_code":"GB","type":"education","lineage":["https://openalex.org/I177639307"]}],"countries":["GB"],"is_corresponding":true,"raw_author_name":"Kate G. Storey","raw_affiliation_strings":["Division of Cell & Developmental Biology, College of Life Sciences, University of Dundee, Dow Street, Dundee DD1 5EH, UK","Division of Cell and Developmental Biology, College of Life Sciences, University of Dundee, Dow Street, Dundee DD1 5EH, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Cell & Developmental Biology, College of Life Sciences, University of Dundee, Dow Street, Dundee DD1 5EH, UK","institution_ids":["https://openalex.org/I177639307"]},{"raw_affiliation_string":"Division of Cell and Developmental Biology, College of Life Sciences, University of Dundee, Dow Street, Dundee DD1 5EH, UK","institution_ids":["https://openalex.org/I177639307"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5000988484"],"corresponding_institution_ids":["https://openalex.org/I177639307"],"apc_list":null,"apc_paid":{"value":4022,"currency":"EUR","value_usd":4337},"fwci":1.9846,"has_fulltext":true,"cited_by_count":340,"citation_normalized_percentile":{"value":0.8852459,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":97,"max":100},"biblio":{"volume":"142","issue":"17","first_page":"2864","last_page":"2875"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10268","display_name":"Developmental Biology and Gene Regulation","score":0.9193999767303467,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10268","display_name":"Developmental Biology and Gene Regulation","score":0.9193999767303467,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10505","display_name":"Pluripotent Stem Cells Research","score":0.04309999942779541,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10608","display_name":"Neurogenesis and neuroplasticity mechanisms","score":0.03480000048875809,"subfield":{"id":"https://openalex.org/subfields/2806","display_name":"Developmental Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/neuromesodermal-progenitors","display_name":"neuromesodermal progenitors","score":0.9890000224113464},{"id":"https://openalex.org/keywords/spinal-cord-development","display_name":"spinal cord development","score":0.949999988079071},{"id":"https://openalex.org/keywords/paraxial-mesoderm","display_name":"paraxial mesoderm","score":0.9350000023841858},{"id":"https://openalex.org/keywords/primitive-streak","display_name":"primitive streak","score":0.8029999732971191},{"id":"https://openalex.org/keywords/epiblast","display_name":"epiblast","score":0.9660000205039978},{"id":"https://openalex.org/keywords/pluripotent-stem-cell-differentiation","display_name":"pluripotent stem cell differentiation","score":0.7870000004768372},{"id":"https://openalex.org/keywords/bipotent-progenitors","display_name":"bipotent progenitors","score":0.6679999828338623},{"id":"https://openalex.org/keywords/neural-induction","display_name":"neural induction","score":0.3540000021457672}],"concepts":[{"id":"https://openalex.org/C75059768","wikidata":"https://www.wikidata.org/wiki/Q519516","display_name":"Epiblast","level":5,"score":0.8823019862174988},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.8441872596740723},{"id":"https://openalex.org/C122428330","wikidata":"https://www.wikidata.org/wiki/Q3816207","display_name":"Paraxial mesoderm","level":5,"score":0.6805843114852905},{"id":"https://openalex.org/C66518211","wikidata":"https://www.wikidata.org/wiki/Q247512","display_name":"Primitive streak","level":5,"score":0.6077504754066467},{"id":"https://openalex.org/C201750760","wikidata":"https://www.wikidata.org/wiki/Q1896218","display_name":"Progenitor cell","level":3,"score":0.5724737644195557},{"id":"https://openalex.org/C15729860","wikidata":"https://www.wikidata.org/wiki/Q2329919","display_name":"Progenitor","level":4,"score":0.5592870116233826},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.5534932613372803},{"id":"https://openalex.org/C2780915607","wikidata":"https://www.wikidata.org/wiki/Q323438","display_name":"Mesoderm","level":4,"score":0.4957521855831146},{"id":"https://openalex.org/C107459253","wikidata":"https://www.wikidata.org/wiki/Q674925","display_name":"Induced pluripotent stem cell","level":4,"score":0.48976564407348633},{"id":"https://openalex.org/C16693951","wikidata":"https://www.wikidata.org/wiki/Q3489847","display_name":"Somitogenesis","level":5,"score":0.4696490168571472},{"id":"https://openalex.org/C2780775167","wikidata":"https://www.wikidata.org/wiki/Q9606","display_name":"Spinal cord","level":2,"score":0.45143184065818787},{"id":"https://openalex.org/C105702510","wikidata":"https://www.wikidata.org/wiki/Q514","display_name":"Anatomy","level":1,"score":0.41338881850242615},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.3756861090660095},{"id":"https://openalex.org/C28328180","wikidata":"https://www.wikidata.org/wiki/Q48196","display_name":"Stem cell","level":2,"score":0.3489570617675781},{"id":"https://openalex.org/C2779018604","wikidata":"https://www.wikidata.org/wiki/Q1427600","display_name":"Somite","level":4,"score":0.2592899203300476},{"id":"https://openalex.org/C129536746","wikidata":"https://www.wikidata.org/wiki/Q1141026","display_name":"Gastrulation","level":4,"score":0.24750807881355286},{"id":"https://openalex.org/C145103041","wikidata":"https://www.wikidata.org/wiki/Q1151519","display_name":"Embryonic stem cell","level":3,"score":0.2377779185771942},{"id":"https://openalex.org/C196843134","wikidata":"https://www.wikidata.org/wiki/Q33196","display_name":"Embryo","level":2,"score":0.2160239815711975},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.17089033126831055},{"id":"https://openalex.org/C87073359","wikidata":"https://www.wikidata.org/wiki/Q33196","display_name":"Embryogenesis","level":3,"score":0.14018693566322327},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004622","descriptor_name":"Embryo, Mammalian","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008648","descriptor_name":"Mesoderm","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":true},{"descriptor_ui":"D013116","descriptor_name":"Spinal Cord","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":true},{"descriptor_ui":"D013116","descriptor_name":"Spinal Cord","qualifier_ui":"Q000196","qualifier_name":"embryology","is_major_topic":true},{"descriptor_ui":"D013234","descriptor_name":"Stem Cells","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":true},{"descriptor_ui":"D015398","descriptor_name":"Signal Transduction","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019521","descriptor_name":"Body Patterning","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D058953","descriptor_name":"Neural Stem Cells","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":false}],"locations_count":6,"locations":[{"id":"doi:10.1242/dev.119768","doi":"https://doi.org/10.1242/dev.119768","is_oa":true,"landing_page_url":"https://doi.org/10.1242/dev.119768","pdf_url":"https://dev.biologists.org/content/develop/142/17/2864.full.pdf","source":{"id":"https://openalex.org/S86558740","display_name":"Development","issn_l":"0950-1991","issn":["0950-1991","1477-9129"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311847","host_organization_name":"The Company of Biologists","host_organization_lineage":["https://openalex.org/P4310311847"],"host_organization_lineage_names":["The Company of Biologists"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Development","raw_type":"journal-article"},{"id":"pmid:26329597","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/26329597","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Development (Cambridge, England)","raw_type":"Journal Article"},{"id":"pmh:oai:discovery.dundee.ac.uk:openaire/5b979d39-93f2-4f4d-8c83-a9dd4081e246","doi":null,"is_oa":true,"landing_page_url":"https://discovery.dundee.ac.uk/en/publications/5b979d39-93f2-4f4d-8c83-a9dd4081e246","pdf_url":null,"source":{"id":"https://openalex.org/S4306400523","display_name":"Discovery Research Portal (University of Dundee)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I177639307","host_organization_name":"University of Dundee","host_organization_lineage":["https://openalex.org/I177639307"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Henrique, D, Abranches, E, Verrier, L & Storey, K G 2015, 'Neuromesodermal progenitors and the making of the spinal cord', Development, vol. 142, no. 17, pp. 2864-2875. https://doi.org/10.1242/dev.119768","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:europepmc.org:3920586","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/4958456","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":null,"raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:4958456","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/4958456","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"Development","raw_type":"Text"},{"id":"pmh:oai:CiteSeerX.psu:10.1.1.1026.7226","doi":null,"is_oa":false,"landing_page_url":"http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.1026.7226","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"http://dev.biologists.org/content/develop/142/17/2864.full.pdf","raw_type":"text"}],"best_oa_location":{"id":"doi:10.1242/dev.119768","doi":"https://doi.org/10.1242/dev.119768","is_oa":true,"landing_page_url":"https://doi.org/10.1242/dev.119768","pdf_url":"https://dev.biologists.org/content/develop/142/17/2864.full.pdf","source":{"id":"https://openalex.org/S86558740","display_name":"Development","issn_l":"0950-1991","issn":["0950-1991","1477-9129"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311847","host_organization_name":"The Company of Biologists","host_organization_lineage":["https://openalex.org/P4310311847"],"host_organization_lineage_names":["The Company of Biologists"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Development","raw_type":"journal-article"},"sustainable_development_goals":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G2182898598","display_name":null,"funder_award_id":"G1100552","funder_id":"https://openalex.org/F4320334626","funder_display_name":"Medical Research Council"},{"id":"https://openalex.org/G5962381034","display_name":null,"funder_award_id":"WT102817","funder_id":"https://openalex.org/F4320311904","funder_display_name":"Wellcome Trust"},{"id":"https://openalex.org/G7949152685","display_name":"Cellular and molecular mechanisms regulating neuronal differentiation in embryos and adults.","funder_award_id":"102817/Z/13/Z","funder_id":"https://openalex.org/F4320311904","funder_display_name":"Wellcome Trust"},{"id":"https://openalex.org/G8628333037","display_name":"Cellular and molecular mechanisms regulating neuronal differentiation in embryos and adults.","funder_award_id":"102817","funder_id":"https://openalex.org/F4320311904","funder_display_name":"Wellcome Trust"},{"id":"https://openalex.org/G8895284798","display_name":"THE DIALECTICS OF STEMNESS: USE OF A NOVEL EMBRYONIC STEM CELL LINE AS A TOOL TO UNVEIL THE FUNCTIONAL ROLE OF NANOG HETEROGENEITY","funder_award_id":"SFRH/BPD/78313/2011","funder_id":"https://openalex.org/F4320334779","funder_display_name":"Funda\u00e7\u00e3o para a Ci\u00eancia e a Tecnologia"}],"funders":[{"id":"https://openalex.org/F4320311904","display_name":"Wellcome Trust","ror":"https://ror.org/029chgv08"},{"id":"https://openalex.org/F4320334626","display_name":"Medical Research Council","ror":"https://ror.org/03x94j517"},{"id":"https://openalex.org/F4320334779","display_name":"Funda\u00e7\u00e3o para a Ci\u00eancia e a Tecnologia","ror":"https://ror.org/00snfqn58"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2135447402.pdf","grobid_xml":"https://content.openalex.org/works/W2135447402.grobid-xml"},"referenced_works_count":113,"referenced_works":["https://openalex.org/W90858298","https://openalex.org/W94784863","https://openalex.org/W1507923114","https://openalex.org/W1530431305","https://openalex.org/W1537836582","https://openalex.org/W1567515623","https://openalex.org/W1605122916","https://openalex.org/W1650449582","https://openalex.org/W1827288309","https://openalex.org/W1877256955","https://openalex.org/W1917459778","https://openalex.org/W1931118778","https://openalex.org/W1933423171","https://openalex.org/W1953764490","https://openalex.org/W1967892860","https://openalex.org/W1968721773","https://openalex.org/W1968819846","https://openalex.org/W1971530006","https://openalex.org/W1975239156","https://openalex.org/W1977130610","https://openalex.org/W1977374662","https://openalex.org/W1977735902","https://openalex.org/W1977898964","https://openalex.org/W1982409288","https://openalex.org/W1984371544","https://openalex.org/W1985023917","https://openalex.org/W1987865998","https://openalex.org/W1989965266","https://openalex.org/W1990818408","https://openalex.org/W1995791606","https://openalex.org/W1997631325","https://openalex.org/W2000447402","https://openalex.org/W2002027942","https://openalex.org/W2004399521","https://openalex.org/W2016871070","https://openalex.org/W2017173986","https://openalex.org/W2020410645","https://openalex.org/W2020458486","https://openalex.org/W2020811145","https://openalex.org/W2021759395","https://openalex.org/W2023401840","https://openalex.org/W2028672386","https://openalex.org/W2030075458","https://openalex.org/W2030211860","https://openalex.org/W2033015985","https://openalex.org/W2034609545","https://openalex.org/W2035510388","https://openalex.org/W2038763845","https://openalex.org/W2039170732","https://openalex.org/W2043807089","https://openalex.org/W2044436799","https://openalex.org/W2044779230","https://openalex.org/W2047717163","https://openalex.org/W2049254977","https://openalex.org/W2050907040","https://openalex.org/W2053626988","https://openalex.org/W2054328435","https://openalex.org/W2054379936","https://openalex.org/W2055397578","https://openalex.org/W2064676044","https://openalex.org/W2065528132","https://openalex.org/W2066832607","https://openalex.org/W2068780842","https://openalex.org/W2070300060","https://openalex.org/W2072069830","https://openalex.org/W2073969798","https://openalex.org/W2075322700","https://openalex.org/W2075805565","https://openalex.org/W2076355203","https://openalex.org/W2079680354","https://openalex.org/W2080549949","https://openalex.org/W2081518960","https://openalex.org/W2087206546","https://openalex.org/W2087786585","https://openalex.org/W2087918775","https://openalex.org/W2094145003","https://openalex.org/W2095452027","https://openalex.org/W2096448447","https://openalex.org/W2096592432","https://openalex.org/W2098737761","https://openalex.org/W2099073211","https://openalex.org/W2099143970","https://openalex.org/W2102735467","https://openalex.org/W2103661362","https://openalex.org/W2104158696","https://openalex.org/W2108500866","https://openalex.org/W2110883354","https://openalex.org/W2117265023","https://openalex.org/W2119816938","https://openalex.org/W2120142812","https://openalex.org/W2128103940","https://openalex.org/W2128393954","https://openalex.org/W2128665076","https://openalex.org/W2141694824","https://openalex.org/W2142514820","https://openalex.org/W2146447597","https://openalex.org/W2146501296","https://openalex.org/W2146978133","https://openalex.org/W2153941478","https://openalex.org/W2155009116","https://openalex.org/W2156659930","https://openalex.org/W2160775930","https://openalex.org/W2166649246","https://openalex.org/W2170104888","https://openalex.org/W2171109270","https://openalex.org/W2183822742","https://openalex.org/W2184947876","https://openalex.org/W2188109752","https://openalex.org/W2417344908","https://openalex.org/W2951944192","https://openalex.org/W2952550014","https://openalex.org/W4253283596","https://openalex.org/W6634021061"],"related_works":["https://openalex.org/W2764189589","https://openalex.org/W4210330271","https://openalex.org/W2953223235","https://openalex.org/W3157783035","https://openalex.org/W4236693100","https://openalex.org/W4408411309","https://openalex.org/W2034609545","https://openalex.org/W3163874554","https://openalex.org/W3160247859","https://openalex.org/W2947532497"],"abstract_inverted_index":{"Neuromesodermal":[0],"progenitors":[1],"(NMps)":[2],"contribute":[3],"to":[4,72],"both":[5],"the":[6,11,29,35,64,78,113,120],"elongating":[7],"spinal":[8],"cord":[9],"and":[10,45,55,84],"adjacent":[12],"paraxial":[13],"mesoderm.":[14],"It":[15],"has":[16],"been":[17],"assumed":[18],"that":[19,38,68,92,103,107],"these":[20,50,93],"cells":[21,52,59,94],"arise":[22,95],"as":[23,34,46],"a":[24,101],"result":[25],"of":[26,28,88,122],"patterning":[27],"anterior":[30,114],"neural":[31,110],"plate.":[32],"However,":[33],"molecular":[36],"mechanisms":[37],"specify":[39],"NMps":[40],"in":[41,60,81,85,112],"vivo":[42,86],"are":[43,62],"uncovered,":[44],"protocols":[47],"for":[48,119,126],"generating":[49],"bipotent":[51],"from":[53,106],"mouse":[54],"human":[56],"pluripotent":[57],"stem":[58],"vitro":[61,82],"established,":[63],"emerging":[65],"data":[66],"suggest":[67],"this":[69],"view":[70],"needs":[71],"be":[73],"revised.":[74],"Here,":[75],"we":[76],"review":[77],"characteristics,":[79],"regulation,":[80],"derivation":[83],"induction":[87],"NMps.":[89],"We":[90,116],"propose":[91],"within":[96],"primitive":[97],"streak-associated":[98],"epiblast":[99],"via":[100],"mechanism":[102],"is":[104],"separable":[105],"which":[108],"establishes":[109],"fate":[111],"epiblast.":[115],"thus":[117],"argue":[118],"existence":[121],"two":[123],"distinct":[124],"routes":[125],"making":[127],"central":[128],"nervous":[129],"system":[130],"progenitors.":[131]},"counts_by_year":[{"year":2026,"cited_by_count":33},{"year":2025,"cited_by_count":29},{"year":2024,"cited_by_count":44},{"year":2023,"cited_by_count":31},{"year":2022,"cited_by_count":34},{"year":2021,"cited_by_count":48},{"year":2020,"cited_by_count":31},{"year":2019,"cited_by_count":28},{"year":2018,"cited_by_count":23},{"year":2017,"cited_by_count":22},{"year":2016,"cited_by_count":13},{"year":2015,"cited_by_count":4}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}