{"id":"https://openalex.org/W2135242557","doi":"https://doi.org/10.1186/1746-1596-7-127","title":"Increased expression of Golgi phosphoprotein-3 is associated with tumor aggressiveness and poor prognosis of prostate cancer","display_name":"Increased expression of Golgi phosphoprotein-3 is associated with tumor aggressiveness and poor prognosis of prostate cancer","publication_year":2012,"publication_date":"2012-09-24","ids":{"openalex":"https://openalex.org/W2135242557","doi":"https://doi.org/10.1186/1746-1596-7-127","mag":"2135242557","pmid":"https://pubmed.ncbi.nlm.nih.gov/23006319","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/3488508"},"language":"en","primary_location":{"id":"doi:10.1186/1746-1596-7-127","doi":"https://doi.org/10.1186/1746-1596-7-127","is_oa":true,"landing_page_url":"https://doi.org/10.1186/1746-1596-7-127","pdf_url":"https://diagnosticpathology.biomedcentral.com/counter/pdf/10.1186/1746-1596-7-127","source":{"id":"https://openalex.org/S124750060","display_name":"Diagnostic Pathology","issn_l":"1746-1596","issn":["1746-1596"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-70","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Diagnostic Pathology","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://diagnosticpathology.biomedcentral.com/counter/pdf/10.1186/1746-1596-7-127","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5100756709","display_name":"Xing Hua","orcid":"https://orcid.org/0000-0002-7614-5607","observed_orcids":["https://orcid.org/0000-0002-7614-5607"]},"institutions":[{"id":"https://openalex.org/I159948400","display_name":"Jinan University","ror":"https://ror.org/02xe5ns62","country_code":"CN","type":"education","lineage":["https://openalex.org/I159948400"]},{"id":"https://openalex.org/I4210103346","display_name":"Nanfang Hospital","ror":"https://ror.org/01eq10738","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210103346"]},{"id":"https://openalex.org/I58200834","display_name":"Southern Medical University","ror":"https://ror.org/01vjw4z39","country_code":"CN","type":"education","lineage":["https://openalex.org/I58200834"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xing Hua","raw_affiliation_strings":["Department of Pathology, Nanfang Hospital, Southern Medical University, 510515 Tonghe, Guangzhou, People's Republic of China","Department of Pathology, Forth Affiliated Hospital of Jinan University, Guangzhou, China","Department of Pathology, Guangzhou Red Cross Hospital, Guangzhou, China","Department of Pathology, Nanfang Hospital, Southern Medical University, Tonghe, People\u2019s Republic of China","Department of Pathology, School of Basic Medical Sciences, Southern Medical University, Tonghe, People\u2019s Republic of China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathology, Nanfang Hospital, Southern Medical University, 510515 Tonghe, Guangzhou, People's Republic of China","institution_ids":["https://openalex.org/I4210103346","https://openalex.org/I58200834"]},{"raw_affiliation_string":"Department of Pathology, Forth Affiliated Hospital of Jinan University, Guangzhou, China","institution_ids":["https://openalex.org/I159948400"]},{"raw_affiliation_string":"Department of Pathology, Guangzhou Red Cross Hospital, Guangzhou, China","institution_ids":[]},{"raw_affiliation_string":"Department of Pathology, Nanfang Hospital, Southern Medical University, Tonghe, People\u2019s Republic of China","institution_ids":["https://openalex.org/I4210103346","https://openalex.org/I58200834"]},{"raw_affiliation_string":"Department of Pathology, School of Basic Medical Sciences, Southern Medical University, Tonghe, People\u2019s Republic of China","institution_ids":["https://openalex.org/I58200834"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100888881","display_name":"Lina Yu","orcid":"https://orcid.org/0009-0004-6608-710X","observed_orcids":["https://orcid.org/0009-0004-6608-710X"]},"institutions":[{"id":"https://openalex.org/I4210103346","display_name":"Nanfang Hospital","ror":"https://ror.org/01eq10738","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210103346"]},{"id":"https://openalex.org/I58200834","display_name":"Southern Medical University","ror":"https://ror.org/01vjw4z39","country_code":"CN","type":"education","lineage":["https://openalex.org/I58200834"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Lina Yu","raw_affiliation_strings":["Department of Pathology, Nanfang Hospital, Southern Medical University, 510515, Tonghe, Guangzhou, People\u2019s Republic of China","Department of Pathology, School of Basic Medical Sciences, Southern Medical University, 510515, Tonghe, Guangzhou, People\u2019s Republic of China","Department of Pathology, Nanfang Hospital, Southern Medical University, Tonghe, People\u2019s Republic of China","Department of Pathology, School of Basic Medical Sciences, Southern Medical University, Tonghe, People\u2019s Republic of China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathology, Nanfang Hospital, Southern Medical University, 510515, Tonghe, Guangzhou, People\u2019s Republic of China","institution_ids":["https://openalex.org/I4210103346","https://openalex.org/I58200834"]},{"raw_affiliation_string":"Department of Pathology, School of Basic Medical Sciences, Southern Medical University, 510515, Tonghe, Guangzhou, People\u2019s Republic of China","institution_ids":["https://openalex.org/I58200834"]},{"raw_affiliation_string":"Department of Pathology, Nanfang Hospital, Southern Medical University, Tonghe, People\u2019s Republic of China","institution_ids":["https://openalex.org/I4210103346","https://openalex.org/I58200834"]},{"raw_affiliation_string":"Department of Pathology, School of Basic Medical Sciences, Southern Medical University, Tonghe, People\u2019s Republic of China","institution_ids":["https://openalex.org/I58200834"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5021669700","display_name":"Wenhai Pan","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I159948400","display_name":"Jinan University","ror":"https://ror.org/02xe5ns62","country_code":"CN","type":"education","lineage":["https://openalex.org/I159948400"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Wenhai Pan","raw_affiliation_strings":["Department of Urology, Forth Affiliated Hospital of Jinan University, Guangzhou, China","Department of Urology, Guangzhou Red Cross Hospital, Guangzhou, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Urology, Forth Affiliated Hospital of Jinan University, Guangzhou, China","institution_ids":["https://openalex.org/I159948400"]},{"raw_affiliation_string":"Department of Urology, Guangzhou Red Cross Hospital, Guangzhou, China","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101859021","display_name":"Xiaoxiao Huang","orcid":"https://orcid.org/0009-0002-5448-6491","observed_orcids":["https://orcid.org/0009-0002-5448-6491"]},"institutions":[{"id":"https://openalex.org/I159948400","display_name":"Jinan University","ror":"https://ror.org/02xe5ns62","country_code":"CN","type":"education","lineage":["https://openalex.org/I159948400"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xiaoxiao Huang","raw_affiliation_strings":["Department of Pathology, Forth Affiliated Hospital of Jinan University, Guangzhou, China","Department of Pathology, Guangzhou Red Cross Hospital, Guangzhou, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathology, Forth Affiliated Hospital of Jinan University, Guangzhou, China","institution_ids":["https://openalex.org/I159948400"]},{"raw_affiliation_string":"Department of Pathology, Guangzhou Red Cross Hospital, Guangzhou, China","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5001510007","display_name":"Zexiao Liao","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I159948400","display_name":"Jinan University","ror":"https://ror.org/02xe5ns62","country_code":"CN","type":"education","lineage":["https://openalex.org/I159948400"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Zexiao Liao","raw_affiliation_strings":["Department of Pathology, Forth Affiliated Hospital of Jinan University, Guangzhou, China","Department of Pathology, Guangzhou Red Cross Hospital, Guangzhou, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathology, Forth Affiliated Hospital of Jinan University, Guangzhou, China","institution_ids":["https://openalex.org/I159948400"]},{"raw_affiliation_string":"Department of Pathology, Guangzhou Red Cross Hospital, Guangzhou, China","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5046349683","display_name":"Qi Xian","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I159948400","display_name":"Jinan University","ror":"https://ror.org/02xe5ns62","country_code":"CN","type":"education","lineage":["https://openalex.org/I159948400"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Qi Xian","raw_affiliation_strings":["Department of Pathology, Forth Affiliated Hospital of Jinan University, Guangzhou, China","Department of Pathology, Guangzhou Red Cross Hospital, Guangzhou, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathology, Forth Affiliated Hospital of Jinan University, Guangzhou, China","institution_ids":["https://openalex.org/I159948400"]},{"raw_affiliation_string":"Department of Pathology, Guangzhou Red Cross Hospital, Guangzhou, China","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100610476","display_name":"Fang Li","orcid":"https://orcid.org/0000-0001-5456-0255","observed_orcids":["https://orcid.org/0000-0001-5456-0255"]},"institutions":[{"id":"https://openalex.org/I159948400","display_name":"Jinan University","ror":"https://ror.org/02xe5ns62","country_code":"CN","type":"education","lineage":["https://openalex.org/I159948400"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Li Fang","raw_affiliation_strings":["Department of Pathology, Forth Affiliated Hospital of Jinan University, Guangzhou, China","Department of Pathology, Guangzhou Red Cross Hospital, Guangzhou, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathology, Forth Affiliated Hospital of Jinan University, Guangzhou, China","institution_ids":["https://openalex.org/I159948400"]},{"raw_affiliation_string":"Department of Pathology, Guangzhou Red Cross Hospital, Guangzhou, China","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5005833440","display_name":"Hong Shen","orcid":"https://orcid.org/0000-0003-1878-7334","observed_orcids":["https://orcid.org/0000-0003-1878-7334","https://orcid.org/0000-0003-0219-3398","https://orcid.org/0009-0006-8628-3989"]},"institutions":[{"id":"https://openalex.org/I4210103346","display_name":"Nanfang Hospital","ror":"https://ror.org/01eq10738","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210103346"]},{"id":"https://openalex.org/I58200834","display_name":"Southern Medical University","ror":"https://ror.org/01vjw4z39","country_code":"CN","type":"education","lineage":["https://openalex.org/I58200834"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Hong Shen","raw_affiliation_strings":["Department of Pathology, Nanfang Hospital, Southern Medical University, 510515, Tonghe, Guangzhou, People\u2019s Republic of China","Department of Pathology, School of Basic Medical Sciences, Southern Medical University, 510515, Tonghe, Guangzhou, People\u2019s Republic of China","Department of Pathology, Nanfang Hospital, Southern Medical University, Tonghe, People\u2019s Republic of China","Department of Pathology, School of Basic Medical Sciences, Southern Medical University, Tonghe, People\u2019s Republic of China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathology, Nanfang Hospital, Southern Medical University, 510515, Tonghe, Guangzhou, People\u2019s Republic of China","institution_ids":["https://openalex.org/I4210103346","https://openalex.org/I58200834"]},{"raw_affiliation_string":"Department of Pathology, School of Basic Medical Sciences, Southern Medical University, 510515, Tonghe, Guangzhou, People\u2019s Republic of China","institution_ids":["https://openalex.org/I58200834"]},{"raw_affiliation_string":"Department of Pathology, Nanfang Hospital, Southern Medical University, Tonghe, People\u2019s Republic of China","institution_ids":["https://openalex.org/I4210103346","https://openalex.org/I58200834"]},{"raw_affiliation_string":"Department of Pathology, School of Basic Medical Sciences, Southern Medical University, Tonghe, People\u2019s Republic of China","institution_ids":["https://openalex.org/I58200834"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5005833440"],"corresponding_institution_ids":["https://openalex.org/I4210103346","https://openalex.org/I58200834"],"apc_list":{"value":2990,"currency":"USD","value_usd":2990},"apc_paid":{"value":2990,"currency":"USD","value_usd":2990},"fwci":4.1648,"has_fulltext":true,"cited_by_count":68,"citation_normalized_percentile":{"value":0.95015185,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":87,"max":100},"biblio":{"volume":"7","issue":"1","first_page":"127","last_page":"127"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10543","display_name":"Prostate Cancer Treatment and Research","score":0.9976000189781189,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10543","display_name":"Prostate Cancer Treatment and Research","score":0.9976000189781189,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10124","display_name":"Prostate Cancer Diagnosis and Treatment","score":0.0010000000474974513,"subfield":{"id":"https://openalex.org/subfields/2748","display_name":"Urology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12465","display_name":"Cancer, Lipids, and Metabolism","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/golph3","display_name":"GOLPH3","score":0.902999997138977},{"id":"https://openalex.org/keywords/prostate-cancer","display_name":"prostate cancer","score":0.9990000128746033},{"id":"https://openalex.org/keywords/castration-resistant-prostate-cancer","display_name":"castration-resistant prostate cancer","score":0.925000011920929},{"id":"https://openalex.org/keywords/prognostic-factors","display_name":"prognostic factors","score":0.8830000162124634},{"id":"https://openalex.org/keywords/disease-free-survival","display_name":"disease-free survival","score":0.8059999942779541},{"id":"https://openalex.org/keywords/overall-survival","display_name":"overall survival","score":0.9860000014305115},{"id":"https://openalex.org/keywords/gleason-score","display_name":"Gleason score","score":0.7110000252723694},{"id":"https://openalex.org/keywords/bone-metastases","display_name":"bone metastasis","score":0.8759999871253967},{"id":"https://openalex.org/keywords/androgen-independence","display_name":"androgen independence","score":0.8849999904632568},{"id":"https://openalex.org/keywords/tumor-aggressiveness","display_name":"tumor aggressiveness","score":0.796999990940094},{"id":"https://openalex.org/keywords/protein-overexpression","display_name":"protein overexpression","score":0.5989999771118164},{"id":"https://openalex.org/keywords/hormone-dependent-prostate-cancer","display_name":"hormone-dependent prostate cancer","score":0.7120000123977661},{"id":"https://openalex.org/keywords/prostatic-intraepithelial-neoplasia","display_name":"prostatic intraepithelial neoplasia","score":0.921999990940094},{"id":"https://openalex.org/keywords/benign-prostatic-hyperplasia","display_name":"benign prostatic hyperplasia","score":0.9549999833106995},{"id":"https://openalex.org/keywords/prostate-specific-antigen","display_name":"prostate-specific antigen","score":0.8560000061988831}],"concepts":[{"id":"https://openalex.org/C2780192828","wikidata":"https://www.wikidata.org/wiki/Q181257","display_name":"Prostate cancer","level":3,"score":0.8035242557525635},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.6681371927261353},{"id":"https://openalex.org/C2776235491","wikidata":"https://www.wikidata.org/wiki/Q9625","display_name":"Prostate","level":3,"score":0.6462962627410889},{"id":"https://openalex.org/C87874733","wikidata":"https://www.wikidata.org/wiki/Q18039844","display_name":"PCA3","level":4,"score":0.6147071123123169},{"id":"https://openalex.org/C193270364","wikidata":"https://www.wikidata.org/wiki/Q17141925","display_name":"Tissue microarray","level":3,"score":0.5670773386955261},{"id":"https://openalex.org/C204232928","wikidata":"https://www.wikidata.org/wiki/Q899285","display_name":"Immunohistochemistry","level":2,"score":0.5499099493026733},{"id":"https://openalex.org/C143998085","wikidata":"https://www.wikidata.org/wiki/Q162555","display_name":"Oncology","level":1,"score":0.549464762210846},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.5096986293792725},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.44535544514656067},{"id":"https://openalex.org/C2777562237","wikidata":"https://www.wikidata.org/wiki/Q835051","display_name":"Hyperplasia","level":2,"score":0.42998605966567993},{"id":"https://openalex.org/C2779534503","wikidata":"https://www.wikidata.org/wiki/Q6058399","display_name":"Intraepithelial neoplasia","level":4,"score":0.4145849645137787},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.3322691321372986}],"mesh":[{"descriptor_ui":"D001859","descriptor_name":"Bone Neoplasms","qualifier_ui":"Q000556","qualifier_name":"secondary","is_major_topic":false},{"descriptor_ui":"D002681","descriptor_name":"China","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007150","descriptor_name":"Immunohistochemistry","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007610","descriptor_name":"Kallikreins","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008565","descriptor_name":"Membrane Proteins","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":true},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009376","descriptor_name":"Neoplasms, Hormone-Dependent","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D009376","descriptor_name":"Neoplasms, Hormone-Dependent","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D009376","descriptor_name":"Neoplasms, Hormone-Dependent","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":false},{"descriptor_ui":"D009376","descriptor_name":"Neoplasms, Hormone-Dependent","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D011237","descriptor_name":"Predictive Value of Tests","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011379","descriptor_name":"Prognosis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011471","descriptor_name":"Prostatic Neoplasms","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D011471","descriptor_name":"Prostatic Neoplasms","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D011471","descriptor_name":"Prostatic Neoplasms","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":false},{"descriptor_ui":"D011471","descriptor_name":"Prostatic Neoplasms","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D012307","descriptor_name":"Risk Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013997","descriptor_name":"Time Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014408","descriptor_name":"Biomarkers, Tumor","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":true},{"descriptor_ui":"D014408","descriptor_name":"Biomarkers, Tumor","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D015854","descriptor_name":"Up-Regulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015999","descriptor_name":"Multivariate Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016009","descriptor_name":"Chi-Square Distribution","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016016","descriptor_name":"Proportional Hazards Models","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017430","descriptor_name":"Prostate-Specific Antigen","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D018450","descriptor_name":"Disease Progression","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018570","descriptor_name":"Risk Assessment","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018572","descriptor_name":"Disease-Free Survival","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D046888","descriptor_name":"Tissue Array Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D053208","descriptor_name":"Kaplan-Meier Estimate","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D060787","descriptor_name":"Neoplasm Grading","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":5,"locations":[{"id":"doi:10.1186/1746-1596-7-127","doi":"https://doi.org/10.1186/1746-1596-7-127","is_oa":true,"landing_page_url":"https://doi.org/10.1186/1746-1596-7-127","pdf_url":"https://diagnosticpathology.biomedcentral.com/counter/pdf/10.1186/1746-1596-7-127","source":{"id":"https://openalex.org/S124750060","display_name":"Diagnostic Pathology","issn_l":"1746-1596","issn":["1746-1596"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-70","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Diagnostic Pathology","raw_type":"journal-article"},{"id":"pmh:oai:europepmc.org:2486968","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3488508","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},{"id":"pmid:23006319","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/23006319","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Diagnostic pathology","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:3488508","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC3488508/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Diagn Pathol","raw_type":"Text"},{"id":"pmh:oai:doaj.org/article:327b36017c1c416cae7805528ca67baa","doi":null,"is_oa":false,"landing_page_url":"https://doaj.org/article/327b36017c1c416cae7805528ca67baa","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Diagnostic Pathology, Vol 7, Iss 1, p 127 (2012)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.1186/1746-1596-7-127","doi":"https://doi.org/10.1186/1746-1596-7-127","is_oa":true,"landing_page_url":"https://doi.org/10.1186/1746-1596-7-127","pdf_url":"https://diagnosticpathology.biomedcentral.com/counter/pdf/10.1186/1746-1596-7-127","source":{"id":"https://openalex.org/S124750060","display_name":"Diagnostic Pathology","issn_l":"1746-1596","issn":["1746-1596"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-70","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Diagnostic Pathology","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.9537000060081482,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[],"funders":[{"id":"https://openalex.org/F4320322161","display_name":"Guangdong Medical Research Foundation","ror":null}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2135242557.pdf","grobid_xml":"https://content.openalex.org/works/W2135242557.grobid-xml"},"referenced_works_count":33,"referenced_works":["https://openalex.org/W177838100","https://openalex.org/W344674368","https://openalex.org/W1580523172","https://openalex.org/W1602137524","https://openalex.org/W1909830141","https://openalex.org/W1963592300","https://openalex.org/W1965732799","https://openalex.org/W1965976637","https://openalex.org/W1985046929","https://openalex.org/W1991062729","https://openalex.org/W1994016727","https://openalex.org/W1999011921","https://openalex.org/W2019480213","https://openalex.org/W2042461504","https://openalex.org/W2048391838","https://openalex.org/W2066086539","https://openalex.org/W2067266580","https://openalex.org/W2074022118","https://openalex.org/W2085181480","https://openalex.org/W2085690923","https://openalex.org/W2087810003","https://openalex.org/W2095255377","https://openalex.org/W2098087713","https://openalex.org/W2100138389","https://openalex.org/W2104968784","https://openalex.org/W2114608969","https://openalex.org/W2131931088","https://openalex.org/W2142335527","https://openalex.org/W2152269520","https://openalex.org/W2155207531","https://openalex.org/W2162464751","https://openalex.org/W2163583831","https://openalex.org/W2403343128"],"related_works":["https://openalex.org/W2105097521","https://openalex.org/W2161489444","https://openalex.org/W4386852093","https://openalex.org/W2266812097","https://openalex.org/W2526391756","https://openalex.org/W2197053368","https://openalex.org/W3216151621","https://openalex.org/W2417937612","https://openalex.org/W2012675034","https://openalex.org/W3138698519"],"abstract_inverted_index":{"BACKGROUND:":[0],"To":[1],"investigate":[2],"the":[3,187,219,226],"expression":[4,35,52,86,103,149,176],"of":[5,27,53,104,201,221,228,246],"Golgi":[6],"phosphoprotein-3":[7],"(GOLPH3)":[8],"in":[9,43,83,87,182,206,250,265],"prostate":[10,29,55,58,66,95,208,229,253],"cancer":[11,67,96,209,230],"and":[12,64,92,133,150,160,248],"determine":[13,46],"its":[14,37,47],"prognostic":[15,48,180,199,244],"value.":[16],"METHODS:":[17],"Immunohistochemical":[18],"staining":[19],"for":[20,280],"GOLPH3":[21,34,51,85,105,148,175,194,222,239,257],"was":[22,40,81,106,144,195,216],"performed":[23],"on":[24],"tissue":[25],"microarrays":[26],"342":[28],"patients.":[30,210],"The":[31,277],"correlation":[32,143],"between":[33,146],"with":[36,90,108,184,225,252],"clinicopathologic":[38],"factors":[39],"also":[41],"analyzed":[42],"order":[44],"to":[45,235,272],"significance.":[49],"RESULTS:":[50],"normal":[54],"tissues,":[56],"benign":[57],"hyperplasia,":[59],"high-grade":[60],"prostatic":[61],"intraepithelial":[62],"neoplasia,":[63],"hormone-dependent":[65],"(HDPC)":[68],"did":[69],"not":[70],"show":[71],"any":[72],"statistically":[73,78],"significant":[74,79],"difference.":[75],"In":[76,212,255],"contrast,":[77],"difference":[80],"reported":[82],"moderate/intense":[84,147,174],"cases":[88],"diagnosed":[89],"HDPC":[91],"castration":[93],"resistant":[94],"(CRPC)":[97],"(P":[98,111,117,122,130,137,203],"<":[99],"0.0005).":[100],"Moderate":[101],"/intense":[102],"associated":[107,224],"androgen":[109],"independence":[110],"=":[112,118,123,131,138,155,158,165,168,204],"0.012),":[113],"higher":[114,125,134],"Gleason":[115],"score":[116],"0.017),":[119],"bone":[120],"metastasis":[121],"0.024),":[124],"baseline":[126],"prostate-specific":[127],"antigen":[128],"(PSA)":[129],"0.038),":[132],"PSA":[135],"nadir":[136],"0.032).":[139],"A":[140],"significantly":[141,179,197],"negative":[142],"found":[145,285],"disease-free":[151],"survival":[152,162],"(DFS)":[153],"(HR":[154,164],"0.28,":[156],"P":[157,167],"0.012)":[159],"overall":[161],"(OS)":[163],"0.42,":[166],"0.027).":[169],"Univariated":[170],"analysis":[171,191],"indicated":[172,192],"that":[173,193,218],"created":[177],"a":[178,196,262,267],"impact":[181],"patients":[183,251],"CRPC.":[185,274],"On":[186],"other":[188],"hand,":[189],"multivariate":[190],"independent":[198],"factor":[200,245],"DFS":[202,247],"0.027)":[205],"all":[207],"CONCLUSIONS:":[211],"this":[213,281],"study,":[214],"it":[215],"discovered":[217],"overexpression":[220],"is":[223],"transition":[227],"from":[231],"hormone":[232,236],"sensitive":[233],"phase":[234],"refractory":[237],"phase.":[238],"might":[240],"be":[241,259,284],"an":[242],"important":[243],"OS":[249],"cancer.":[254],"totality,":[256],"could":[258],"used":[260],"as":[261],"novel":[263],"candidate":[264],"devising":[266],"more":[268],"effective":[269],"therapeutic":[270],"strategy":[271],"tackle":[273],"VIRTUAL":[275],"SLIDES:":[276],"virtual":[278],"slide(s)":[279],"article":[282],"can":[283],"here:":[286],"http://www.diagnosticpathology.diagnomx.eu/vs/1452541171722856.":[287]},"counts_by_year":[{"year":2026,"cited_by_count":3},{"year":2025,"cited_by_count":2},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":2},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":2},{"year":2019,"cited_by_count":6},{"year":2018,"cited_by_count":2},{"year":2017,"cited_by_count":2},{"year":2016,"cited_by_count":6},{"year":2015,"cited_by_count":15},{"year":2014,"cited_by_count":16},{"year":2013,"cited_by_count":8},{"year":2012,"cited_by_count":2}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2016-06-24T00:00:00"}