{"id":"https://openalex.org/W2134714976","doi":"https://doi.org/10.1136/oemed-2014-102119","title":"Rat-specific IgG and IgG 4 antibodies associated with inhibition of IgE\u2013allergen complex binding in laboratory animal workers","display_name":"Rat-specific IgG and IgG 4 antibodies associated with inhibition of IgE\u2013allergen complex binding in laboratory animal workers","publication_year":2014,"publication_date":"2014-06-18","ids":{"openalex":"https://openalex.org/W2134714976","doi":"https://doi.org/10.1136/oemed-2014-102119","mag":"2134714976","pmid":"https://pubmed.ncbi.nlm.nih.gov/24944289"},"language":"en","primary_location":{"id":"doi:10.1136/oemed-2014-102119","doi":"https://doi.org/10.1136/oemed-2014-102119","is_oa":false,"landing_page_url":"https://doi.org/10.1136/oemed-2014-102119","pdf_url":null,"source":{"id":"https://openalex.org/S159252376","display_name":"Occupational and Environmental Medicine","issn_l":"0007-1072","issn":["0007-1072","1351-0711","1470-7926"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-3","ki-jl-1","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319945","host_organization_name":"BMJ","host_organization_lineage":["https://openalex.org/P4310319945"],"host_organization_lineage_names":["BMJ"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Occupational and Environmental Medicine","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":null,"display_name":"M Jones","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I47508984","display_name":"Imperial College London","ror":"https://ror.org/041kmwe10","country_code":"GB","type":"education","lineage":["https://openalex.org/I47508984"]}],"countries":["GB"],"is_corresponding":true,"raw_author_name":"M Jones","raw_affiliation_strings":["Department of Occupational and Environmental Medicine, National Heart and Lung Institute, Imperial College London, London, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Occupational and Environmental Medicine, National Heart and Lung Institute, Imperial College London, London, UK","institution_ids":["https://openalex.org/I47508984"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5066512608","display_name":"H. Jeal","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I47508984","display_name":"Imperial College London","ror":"https://ror.org/041kmwe10","country_code":"GB","type":"education","lineage":["https://openalex.org/I47508984"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"H Jeal","raw_affiliation_strings":["Department of Occupational and Environmental Medicine, National Heart and Lung Institute, Imperial College London, London, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Occupational and Environmental Medicine, National Heart and Lung Institute, Imperial College London, London, UK","institution_ids":["https://openalex.org/I47508984"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5032497873","display_name":"Susie J. Schofield","orcid":"https://orcid.org/0000-0002-3135-9783","observed_orcids":["https://orcid.org/0000-0002-3135-9783"]},"institutions":[{"id":"https://openalex.org/I47508984","display_name":"Imperial College London","ror":"https://ror.org/041kmwe10","country_code":"GB","type":"education","lineage":["https://openalex.org/I47508984"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"S Schofield","raw_affiliation_strings":["Department of Occupational and Environmental Medicine, National Heart and Lung Institute, Imperial College London, London, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Occupational and Environmental Medicine, National Heart and Lung Institute, Imperial College London, London, UK","institution_ids":["https://openalex.org/I47508984"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5079012045","display_name":"Jessica M. Harris","orcid":"https://orcid.org/0000-0002-4605-7710","observed_orcids":["https://orcid.org/0000-0002-4605-7710"]},"institutions":[{"id":"https://openalex.org/I36234482","display_name":"University of Bristol","ror":"https://ror.org/0524sp257","country_code":"GB","type":"education","lineage":["https://openalex.org/I36234482"]},{"id":"https://openalex.org/I47508984","display_name":"Imperial College London","ror":"https://ror.org/041kmwe10","country_code":"GB","type":"education","lineage":["https://openalex.org/I47508984"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"J M Harris","raw_affiliation_strings":["Department of Occupational and Environmental Medicine, National Heart and Lung Institute, Imperial College London, London, UK","Bristol Medical School (THS)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Occupational and Environmental Medicine, National Heart and Lung Institute, Imperial College London, London, UK","institution_ids":["https://openalex.org/I47508984"]},{"raw_affiliation_string":"Bristol Medical School (THS)","institution_ids":["https://openalex.org/I36234482"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5063862530","display_name":"Mohamed H. Shamji","orcid":"https://orcid.org/0000-0003-3425-3463","observed_orcids":["https://orcid.org/0000-0003-3425-3463"]},"institutions":[{"id":"https://openalex.org/I4210141571","display_name":"Asthma UK","ror":"https://ror.org/03z7xev21","country_code":"GB","type":"nonprofit","lineage":["https://openalex.org/I2801572420","https://openalex.org/I4210141571"]},{"id":"https://openalex.org/I47508984","display_name":"Imperial College London","ror":"https://ror.org/041kmwe10","country_code":"GB","type":"education","lineage":["https://openalex.org/I47508984"]},{"id":"https://openalex.org/I90344618","display_name":"Medical Research Council","ror":"https://ror.org/03x94j517","country_code":"GB","type":"government","lineage":["https://openalex.org/I4210087105","https://openalex.org/I90344618"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"M H Shamji","raw_affiliation_strings":["Department of Allergy and Clinical Immunology, National Heart and Lung Institute, Imperial College London, part of the Medical Research Council and Asthma UK Centre for Allergic Mechanisms of Asthma, London, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Allergy and Clinical Immunology, National Heart and Lung Institute, Imperial College London, part of the Medical Research Council and Asthma UK Centre for Allergic Mechanisms of Asthma, London, UK","institution_ids":["https://openalex.org/I4210141571","https://openalex.org/I47508984","https://openalex.org/I90344618"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5076345391","display_name":"James N. Francis","orcid":"https://orcid.org/0000-0002-6496-2546","observed_orcids":["https://orcid.org/0000-0002-6496-2546"]},"institutions":[{"id":"https://openalex.org/I4210141571","display_name":"Asthma UK","ror":"https://ror.org/03z7xev21","country_code":"GB","type":"nonprofit","lineage":["https://openalex.org/I2801572420","https://openalex.org/I4210141571"]},{"id":"https://openalex.org/I47508984","display_name":"Imperial College London","ror":"https://ror.org/041kmwe10","country_code":"GB","type":"education","lineage":["https://openalex.org/I47508984"]},{"id":"https://openalex.org/I90344618","display_name":"Medical Research Council","ror":"https://ror.org/03x94j517","country_code":"GB","type":"government","lineage":["https://openalex.org/I4210087105","https://openalex.org/I90344618"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"J N Francis","raw_affiliation_strings":["Department of Allergy and Clinical Immunology, National Heart and Lung Institute, Imperial College London, part of the Medical Research Council and Asthma UK Centre for Allergic Mechanisms of Asthma, London, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Allergy and Clinical Immunology, National Heart and Lung Institute, Imperial College London, part of the Medical Research Council and Asthma UK Centre for Allergic Mechanisms of Asthma, London, UK","institution_ids":["https://openalex.org/I4210141571","https://openalex.org/I47508984","https://openalex.org/I90344618"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5043192106","display_name":"Stephen R. Durham","orcid":"https://orcid.org/0000-0001-5264-6207","observed_orcids":["https://orcid.org/0000-0001-5264-6207"]},"institutions":[{"id":"https://openalex.org/I4210141571","display_name":"Asthma UK","ror":"https://ror.org/03z7xev21","country_code":"GB","type":"nonprofit","lineage":["https://openalex.org/I2801572420","https://openalex.org/I4210141571"]},{"id":"https://openalex.org/I47508984","display_name":"Imperial College London","ror":"https://ror.org/041kmwe10","country_code":"GB","type":"education","lineage":["https://openalex.org/I47508984"]},{"id":"https://openalex.org/I90344618","display_name":"Medical Research Council","ror":"https://ror.org/03x94j517","country_code":"GB","type":"government","lineage":["https://openalex.org/I4210087105","https://openalex.org/I90344618"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"S R Durham","raw_affiliation_strings":["Department of Allergy and Clinical Immunology, National Heart and Lung Institute, Imperial College London, part of the Medical Research Council and Asthma UK Centre for Allergic Mechanisms of Asthma, London, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Allergy and Clinical Immunology, National Heart and Lung Institute, Imperial College London, part of the Medical Research Council and Asthma UK Centre for Allergic Mechanisms of Asthma, London, UK","institution_ids":["https://openalex.org/I4210141571","https://openalex.org/I47508984","https://openalex.org/I90344618"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5075776335","display_name":"Paul Cullinan","orcid":"https://orcid.org/0000-0002-9314-6468","observed_orcids":["https://orcid.org/0000-0002-9314-6468"]},"institutions":[{"id":"https://openalex.org/I47508984","display_name":"Imperial College London","ror":"https://ror.org/041kmwe10","country_code":"GB","type":"education","lineage":["https://openalex.org/I47508984"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"P Cullinan","raw_affiliation_strings":["Department of Occupational and Environmental Medicine, National Heart and Lung Institute, Imperial College London, London, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Occupational and Environmental Medicine, National Heart and Lung Institute, Imperial College London, London, UK","institution_ids":["https://openalex.org/I47508984"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I47508984"],"apc_list":null,"apc_paid":null,"fwci":2.7958,"has_fulltext":false,"cited_by_count":21,"citation_normalized_percentile":{"value":0.89597568,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":87,"max":98},"biblio":{"volume":"71","issue":"9","first_page":"619","last_page":"623"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12208","display_name":"Occupational exposure and asthma","score":0.9585000276565552,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T12208","display_name":"Occupational exposure and asthma","score":0.9585000276565552,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10877","display_name":"Allergic Rhinitis and Sensitization","score":0.03189999982714653,"subfield":{"id":"https://openalex.org/subfields/2723","display_name":"Immunology and Allergy"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10634","display_name":"Food Allergy and Anaphylaxis Research","score":0.004699999932199717,"subfield":{"id":"https://openalex.org/subfields/2723","display_name":"Immunology and Allergy"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/laboratory-animal-allergy","display_name":"laboratory animal allergy","score":0.8339999914169312},{"id":"https://openalex.org/keywords/rodent-allergens","display_name":"rodent allergens","score":0.9300000071525574},{"id":"https://openalex.org/keywords/igg4","display_name":"IgG4","score":0.8700000047683716},{"id":"https://openalex.org/keywords/b-cells","display_name":"B cells","score":0.9020000100135803},{"id":"https://openalex.org/keywords/allergen-exposure","display_name":"allergen exposure","score":0.8489999771118164},{"id":"https://openalex.org/keywords/occupational-allergy","display_name":"occupational allergy","score":0.5580000281333923},{"id":"https://openalex.org/keywords/clinical-tolerance","display_name":"clinical tolerance","score":0.44600000977516174},{"id":"https://openalex.org/keywords/laboratory-animal-workers","display_name":"laboratory animal workers","score":0.765999972820282}],"concepts":[{"id":"https://openalex.org/C141105273","wikidata":"https://www.wikidata.org/wiki/Q79455","display_name":"Immunoglobulin E","level":3,"score":0.867050290107727},{"id":"https://openalex.org/C2780510475","wikidata":"https://www.wikidata.org/wiki/Q186752","display_name":"Allergen","level":3,"score":0.7850936651229858},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.7357339859008789},{"id":"https://openalex.org/C159654299","wikidata":"https://www.wikidata.org/wiki/Q79460","display_name":"Antibody","level":2,"score":0.7030714750289917},{"id":"https://openalex.org/C34814297","wikidata":"https://www.wikidata.org/wiki/Q4845302","display_name":"CD23","level":4,"score":0.6482025980949402},{"id":"https://openalex.org/C207480886","wikidata":"https://www.wikidata.org/wiki/Q42982","display_name":"Allergy","level":2,"score":0.5761975646018982},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.5334159731864929},{"id":"https://openalex.org/C2780898057","wikidata":"https://www.wikidata.org/wiki/Q79448","display_name":"Immunoglobulin G","level":3,"score":0.47914189100265503}],"mesh":[{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000485","descriptor_name":"Allergens","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D000704","descriptor_name":"Analysis of Variance","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001402","descriptor_name":"B-Lymphocytes","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D003430","descriptor_name":"Cross-Sectional Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006113","descriptor_name":"United Kingdom","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006967","descriptor_name":"Hypersensitivity","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D007073","descriptor_name":"Immunoglobulin E","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D007074","descriptor_name":"Immunoglobulin G","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009784","descriptor_name":"Occupational Diseases","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D012882","descriptor_name":"Skin Tests","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016273","descriptor_name":"Occupational Exposure","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":true},{"descriptor_ui":"D017750","descriptor_name":"Animal Technicians","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D051381","descriptor_name":"Rats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":5,"locations":[{"id":"doi:10.1136/oemed-2014-102119","doi":"https://doi.org/10.1136/oemed-2014-102119","is_oa":false,"landing_page_url":"https://doi.org/10.1136/oemed-2014-102119","pdf_url":null,"source":{"id":"https://openalex.org/S159252376","display_name":"Occupational and Environmental Medicine","issn_l":"0007-1072","issn":["0007-1072","1351-0711","1470-7926"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-3","ki-jl-1","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319945","host_organization_name":"BMJ","host_organization_lineage":["https://openalex.org/P4310319945"],"host_organization_lineage_names":["BMJ"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Occupational and Environmental Medicine","raw_type":"journal-article"},{"id":"pmid:24944289","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/24944289","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Occupational and environmental medicine","raw_type":"Journal Article"},{"id":"pmh:oai:research-information.bris.ac.uk:publications/6c77edcd-1c62-4b1f-a32a-fa4838d2def4","doi":null,"is_oa":false,"landing_page_url":"https://research-information.bris.ac.uk/en/publications/6c77edcd-1c62-4b1f-a32a-fa4838d2def4","pdf_url":null,"source":{"id":"https://openalex.org/S7407055359","display_name":"Explore Bristol Research","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Jones, M, Jeal, H, Schofield, S, Harris, J M, Shamji, M H, Francis, J N, Durham, S R & Cullinan, P 2014, 'Rat-specific IgG and IgG\u2084 antibodies associated with inhibition of IgE-allergen complex binding in laboratory animal workers', Occupational and Environmental Medicine, vol. 71, no. 9, pp. 619-23. https://doi.org/10.1136/oemed-2014-102119","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:open-archive.highwire.org:oemed:71/9/619","doi":null,"is_oa":false,"landing_page_url":"http://oem.bmj.com/cgi/content/short/71/9/619","pdf_url":null,"source":{"id":"https://openalex.org/S4406923041","display_name":"HighWire Press Open Archive","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"TEXT"},{"id":"pmh:oai:research-information.bris.ac.uk:openaire_cris_publications/6c77edcd-1c62-4b1f-a32a-fa4838d2def4","doi":null,"is_oa":false,"landing_page_url":"https://research-information.bris.ac.uk/en/publications/6c77edcd-1c62-4b1f-a32a-fa4838d2def4","pdf_url":null,"source":{"id":"https://openalex.org/S4306400895","display_name":"Bristol Research (University of Bristol)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I36234482","host_organization_name":"University of Bristol","host_organization_lineage":["https://openalex.org/I36234482"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Jones, M, Jeal, H, Schofield, S, Harris, J M, Shamji, M H, Francis, J N, Durham, S R & Cullinan, P 2014, 'Rat-specific IgG and IgG\u2084 antibodies associated with inhibition of IgE-allergen complex binding in laboratory animal workers', Occupational and Environmental Medicine, vol. 71, no. 9, pp. 619-23. https://doi.org/10.1136/oemed-2014-102119","raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.9391000270843506,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[],"funders":[{"id":"https://openalex.org/F4320314903","display_name":"Immune Tolerance Network","ror":"https://ror.org/00pjnm784"},{"id":"https://openalex.org/F4320320066","display_name":"Asthma and Lung UK","ror":"https://ror.org/03z7xev21"},{"id":"https://openalex.org/F4320320340","display_name":"Colt Foundation","ror":"https://ror.org/02kcqb193"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":19,"referenced_works":["https://openalex.org/W1524200221","https://openalex.org/W1782792704","https://openalex.org/W1946194739","https://openalex.org/W1973688027","https://openalex.org/W1990702493","https://openalex.org/W2011120760","https://openalex.org/W2017960889","https://openalex.org/W2018350662","https://openalex.org/W2022444559","https://openalex.org/W2046574729","https://openalex.org/W2071392555","https://openalex.org/W2104772500","https://openalex.org/W2111252732","https://openalex.org/W2122441923","https://openalex.org/W2150888210","https://openalex.org/W2158308846","https://openalex.org/W2169664925","https://openalex.org/W2225736872","https://openalex.org/W3035477170"],"related_works":["https://openalex.org/W7096098928","https://openalex.org/W2071754188","https://openalex.org/W2022444559","https://openalex.org/W1782792704","https://openalex.org/W7154562234","https://openalex.org/W1946194739","https://openalex.org/W1981258520","https://openalex.org/W2159106865","https://openalex.org/W2092549062","https://openalex.org/W2013060770"],"abstract_inverted_index":{"OBJECTIVES:":[0],"The":[1],"relationship":[2],"between":[3],"exposure":[4,62,118],"to":[5,42,83,107,141,158,200],"rodent":[6],"allergens":[7],"and":[8,24,36,51,151,169],"laboratory":[9,67,93,196],"animal":[10,68,94,197],"allergy":[11],"is":[12,19],"complex;":[13],"at":[14,59,223],"highest":[15,177,224],"allergen":[16,61,167,225],"exposures":[17,178],"there":[18],"an":[20],"attenuation":[21,220],"of":[22,32,48,66,76,79,92,127,147,221],"sensitisation":[23],"symptoms":[25],"which":[26],"are":[27],"associated":[28],"with":[29,144,165,176,206],"increased":[30,46],"levels":[31,47],"rat-specific":[33,49,149,192],"immunoglobulin":[34],"(Ig)G":[35],"IgG4":[37,52,152],"antibodies.":[38],"We":[39,132],"set":[40],"out":[41],"examine":[43],"whether":[44],"the":[45,77,174,219],"IgG":[50,150],"antibodies":[53,153,194],"that":[54,201],"we":[55],"have":[56],"previously":[57],"observed":[58,133,202],"high":[60,166,207],"in":[63,97,112,137,163,173,195,203],"our":[64],"cohort":[65],"workers":[69,95,164],"play":[70],"a":[71,134,188,215],"functional":[72,189],"role":[73,190],"through":[74],"blockage":[75],"binding":[78,82,106,140,157],"IgE-allergen":[80,104,138,155],"complex":[81,105,139,156],"CD23":[84],"receptors":[85],"on":[86],"B":[87,108,142,159],"cells.":[88],"METHODS:":[89],"Cross-sectional":[90],"survey":[91],"(n=776)":[96],"six":[98],"UK":[99],"pharmaceutical":[100],"companies":[101],"were":[102],"surveyed.":[103],"cells":[109,143,160],"was":[110,119,161],"measured":[111],"703":[113],"(97.9%)":[114],"eligible":[115],"employees;":[116],"their":[117],"categorised":[120],"by":[121],"either":[122],"job":[123],"group":[124],"or":[125],"number":[126],"rats":[128],"handled":[129],"daily.":[130],"RESULTS:":[131],"significant":[135],"decrease":[136],"increasing":[145],"quartiles":[146],"both":[148],"(p<0.001).":[154],"lower":[162],"exposure,":[168],"significantly":[170],"so":[171],"(p=0.033)":[172],"subgroup":[175],"but":[179],"no":[180],"work-related":[181],"chest":[182],"symptoms.":[183],"CONCLUSIONS:":[184],"These":[185],"findings":[186],"demonstrate":[187],"for":[191,218],"IgG/G4":[193],"workers,":[198],"similar":[199],"patients":[204],"treated":[205],"dose":[208],"immunotherapy":[209],"who":[210],"become":[211],"clinically":[212],"tolerant,":[213],"suggesting":[214],"potential":[216],"explanation":[217],"risk":[222],"exposures.":[226]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":2},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":2},{"year":2018,"cited_by_count":2},{"year":2017,"cited_by_count":3},{"year":2016,"cited_by_count":4},{"year":2015,"cited_by_count":1},{"year":2014,"cited_by_count":1}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2016-06-24T00:00:00"}
