{"id":"https://openalex.org/W2134605133","doi":"https://doi.org/10.1242/jcs.101.3.547","title":"Mutants of the microtubule motor protein, nonclaret disjunctional, affect spindle structure and chromosome movement in meiosis and mitosis","display_name":"Mutants of the microtubule motor protein, nonclaret disjunctional, affect spindle structure and chromosome movement in meiosis and mitosis","publication_year":1992,"publication_date":"1992-03-01","ids":{"openalex":"https://openalex.org/W2134605133","doi":"https://doi.org/10.1242/jcs.101.3.547","mag":"2134605133","pmid":"https://pubmed.ncbi.nlm.nih.gov/1522143"},"language":"en","primary_location":{"id":"doi:10.1242/jcs.101.3.547","doi":"https://doi.org/10.1242/jcs.101.3.547","is_oa":false,"landing_page_url":"https://doi.org/10.1242/jcs.101.3.547","pdf_url":null,"source":{"id":"https://openalex.org/S5677253","display_name":"Journal of Cell Science","issn_l":"0021-9533","issn":["0021-9533","1477-9137"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310311847","host_organization_name":"The Company of Biologists","host_organization_lineage":["https://openalex.org/P4310311847"],"host_organization_lineage_names":["The Company of Biologists"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Cell Science","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5047797838","display_name":"Machiko Hatsumi","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210126298","display_name":"Duke Medical Center","ror":"https://ror.org/03njmea73","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210126298","https://openalex.org/I4210144876"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Machiko Hatsumi","raw_affiliation_strings":["Duke University Medical Center, Durham Department of Microbiology & Immunology , , North Carolina 27710, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Duke University Medical Center, Durham Department of Microbiology & Immunology , , North Carolina 27710, USA","institution_ids":["https://openalex.org/I4210126298"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5077636721","display_name":"Sharyn A. Endow","orcid":"https://orcid.org/0000-0002-0907-8889","observed_orcids":["https://orcid.org/0000-0002-0907-8889"]},"institutions":[{"id":"https://openalex.org/I4210126298","display_name":"Duke Medical Center","ror":"https://ror.org/03njmea73","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210126298","https://openalex.org/I4210144876"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Sharyn A. Endow","raw_affiliation_strings":["Duke University Medical Center, Durham Department of Microbiology & Immunology , , North Carolina 27710, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Duke University Medical Center, Durham Department of Microbiology & Immunology , , North Carolina 27710, USA","institution_ids":["https://openalex.org/I4210126298"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I4210126298"],"apc_list":null,"apc_paid":null,"fwci":2.884,"has_fulltext":false,"cited_by_count":137,"citation_normalized_percentile":{"value":0.90969823,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":88,"max":99},"biblio":{"volume":"101","issue":"3","first_page":"547","last_page":"559"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10492","display_name":"Microtubule and mitosis dynamics","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10492","display_name":"Microtubule and mitosis dynamics","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10222","display_name":"Genomics and Chromatin Dynamics","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10268","display_name":"Developmental Biology and Gene Regulation","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/microtubule-motors","display_name":"microtubule motor proteins","score":0.8309999704360962},{"id":"https://openalex.org/keywords/meiotic-spindle-assembly","display_name":"meiotic spindle assembly","score":0.6850000023841858},{"id":"https://openalex.org/keywords/chromosome-segregation","display_name":"chromosome segregation","score":0.7179999947547913},{"id":"https://openalex.org/keywords/meiosis","display_name":"meiosis","score":0.6320000290870667},{"id":"https://openalex.org/keywords/mitosis","display_name":"mitosis","score":0.9940000176429749},{"id":"https://openalex.org/keywords/drosophila-oocyte","display_name":"Drosophila oocyte","score":0.8330000042915344},{"id":"https://openalex.org/keywords/spindle-poles","display_name":"spindle poles","score":0.7900000214576721},{"id":"https://openalex.org/keywords/chromosome-movement","display_name":"chromosome movement","score":0.656000018119812}],"concepts":[{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.8686561584472656},{"id":"https://openalex.org/C148196450","wikidata":"https://www.wikidata.org/wiki/Q21100485","display_name":"Meiosis","level":3,"score":0.8093690872192383},{"id":"https://openalex.org/C93304396","wikidata":"https://www.wikidata.org/wiki/Q14763008","display_name":"Mitosis","level":2,"score":0.7432635426521301},{"id":"https://openalex.org/C2778354886","wikidata":"https://www.wikidata.org/wiki/Q5113927","display_name":"Chromosome segregation","level":4,"score":0.706315279006958},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.621474027633667},{"id":"https://openalex.org/C47432576","wikidata":"https://www.wikidata.org/wiki/Q918594","display_name":"Spindle apparatus","level":4,"score":0.6206256151199341},{"id":"https://openalex.org/C70547292","wikidata":"https://www.wikidata.org/wiki/Q12386518","display_name":"Spindle pole body","level":5,"score":0.5553339719772339},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.5518772602081299},{"id":"https://openalex.org/C2910992960","wikidata":"https://www.wikidata.org/wiki/Q21100485","display_name":"Meiosis II","level":4,"score":0.5157740116119385},{"id":"https://openalex.org/C20418707","wikidata":"https://www.wikidata.org/wiki/Q189933","display_name":"Microtubule","level":2,"score":0.4610414206981659},{"id":"https://openalex.org/C30481170","wikidata":"https://www.wikidata.org/wiki/Q37748","display_name":"Chromosome","level":3,"score":0.43656760454177856},{"id":"https://openalex.org/C93126451","wikidata":"https://www.wikidata.org/wiki/Q2383767","display_name":"Motor protein","level":3,"score":0.4261026084423065},{"id":"https://openalex.org/C85813293","wikidata":"https://www.wikidata.org/wiki/Q188909","display_name":"Cell division","level":3,"score":0.18051159381866455},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.07625922560691833},{"id":"https://openalex.org/C1491633281","wikidata":"https://www.wikidata.org/wiki/Q7868","display_name":"Cell","level":2,"score":0.03707402944564819}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002875","descriptor_name":"Chromosomes","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D003433","descriptor_name":"Crosses, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004330","descriptor_name":"Drosophila","qualifier_ui":"Q000196","qualifier_name":"embryology","is_major_topic":false},{"descriptor_ui":"D004330","descriptor_name":"Drosophila","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008540","descriptor_name":"Meiosis","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D008540","descriptor_name":"Meiosis","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D008856","descriptor_name":"Microscopy, Fluorescence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008868","descriptor_name":"Microtubule Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D008870","descriptor_name":"Microtubules","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D008938","descriptor_name":"Mitosis","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D008938","descriptor_name":"Mitosis","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D008941","descriptor_name":"Spindle Apparatus","qualifier_ui":"Q000648","qualifier_name":"ultrastructure","is_major_topic":true},{"descriptor_ui":"D009154","descriptor_name":"Mutation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D009865","descriptor_name":"Oocytes","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":false},{"descriptor_ui":"D009865","descriptor_name":"Oocytes","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D010858","descriptor_name":"Pigmentation","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D016547","descriptor_name":"Kinesins","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D029721","descriptor_name":"Drosophila Proteins","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":3,"locations":[{"id":"doi:10.1242/jcs.101.3.547","doi":"https://doi.org/10.1242/jcs.101.3.547","is_oa":false,"landing_page_url":"https://doi.org/10.1242/jcs.101.3.547","pdf_url":null,"source":{"id":"https://openalex.org/S5677253","display_name":"Journal of Cell Science","issn_l":"0021-9533","issn":["0021-9533","1477-9137"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310311847","host_organization_name":"The Company of Biologists","host_organization_lineage":["https://openalex.org/P4310311847"],"host_organization_lineage_names":["The Company of Biologists"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Cell Science","raw_type":"journal-article"},{"id":"pmid:1522143","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/1522143","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of cell science","raw_type":"Journal Article"},{"id":"pmh:oai:open-archive.highwire.org:joces:101/3/547","doi":null,"is_oa":false,"landing_page_url":"http://jcs.biologists.org/cgi/content/short/101/3/547","pdf_url":null,"source":{"id":"https://openalex.org/S4406923041","display_name":"HighWire Press Open Archive","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"TEXT"}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G6048685197","display_name":"Chromosome Movement in Meiosis and Mitosis","funder_award_id":"R01GM046225","funder_id":"https://openalex.org/F4320337354","funder_display_name":"National Institute of General Medical Sciences"}],"funders":[{"id":"https://openalex.org/F4320337354","display_name":"National Institute of General Medical Sciences","ror":"https://ror.org/04q48ey07"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":32,"referenced_works":["https://openalex.org/W61326889","https://openalex.org/W328381318","https://openalex.org/W1545962441","https://openalex.org/W1546084977","https://openalex.org/W1882055915","https://openalex.org/W1975961272","https://openalex.org/W1979507216","https://openalex.org/W1990861148","https://openalex.org/W2000164138","https://openalex.org/W2016432685","https://openalex.org/W2046030002","https://openalex.org/W2049611094","https://openalex.org/W2054835736","https://openalex.org/W2055031584","https://openalex.org/W2067831351","https://openalex.org/W2070944436","https://openalex.org/W2080351280","https://openalex.org/W2086544026","https://openalex.org/W2089080814","https://openalex.org/W2094247207","https://openalex.org/W2102340487","https://openalex.org/W2109509608","https://openalex.org/W2128147740","https://openalex.org/W2131113110","https://openalex.org/W2132737280","https://openalex.org/W2143708956","https://openalex.org/W2151793977","https://openalex.org/W2152845528","https://openalex.org/W2160969163","https://openalex.org/W2163704200","https://openalex.org/W2319532902","https://openalex.org/W2421915954"],"related_works":["https://openalex.org/W2106258850","https://openalex.org/W2162786198","https://openalex.org/W2118506779","https://openalex.org/W1602392847","https://openalex.org/W2105127342","https://openalex.org/W2007053887","https://openalex.org/W3040688946","https://openalex.org/W2101613161","https://openalex.org/W1992150353","https://openalex.org/W349165566"],"abstract_inverted_index":{"The":[0,50,88,118,153],"Drosophila":[1,28],"microtubule":[2],"motor":[3,79,148,155],"protein,":[4],"nonclaret":[5],"disjunctional":[6],"(ncd),":[7],"is":[8,98,150],"required":[9,99],"for":[10,100,143],"proper":[11,101],"chromosome":[12,48,64,125],"distribution":[13,126],"in":[14,26,55,59,74,110,116,160,168],"meiosis":[15,60,67],"and":[16,23,30,33,42,47,62,69,105,123],"mitosis.":[17],"We":[18],"have":[19],"examined":[20],"the":[21,34,78,169,174],"meiotic":[22,102,122],"mitotic":[24,86,124,171],"divisions":[25,72,172],"wild-type":[27],"oocytes":[29],"early":[31,58,75,85,170],"embryos,":[32],"effects":[35,89],"of":[36,77,90,120,173],"three":[37],"ncd":[38,41,51,97,128,144,154],"mutants":[39,52,91,129],"(cand,":[40],"ncdD)":[43],"on":[44,92],"spindle":[45,56,93,103,114,138],"structure":[46,57,94],"movement.":[49],"cause":[53],"abnormalities":[54],"I,":[61],"abnormal":[63,84],"configurations":[65],"throughout":[66],"I":[68],"II.":[70],"Defective":[71],"continue":[73],"embryos":[76],"null":[80],"mutant,":[81],"cand,":[82],"with":[83],"spindles.":[87],"suggest":[95],"that":[96],"assembly,":[104],"may":[106],"play":[107],"a":[108,137,141,146],"role":[109,135,142,167],"forming":[111],"or":[112],"maintaining":[113],"poles":[115],"meiosis.":[117],"disruption":[119],"normal":[121],"by":[127],"can":[130],"be":[131],"attributed":[132],"to":[133],"its":[134],"as":[136,145],"motor,":[139],"although":[140],"chromosome-associated":[147],"protein":[149,156],"not":[151,158],"excluded.":[152],"functions":[157],"only":[159],"meiosis,":[161],"but":[162],"also":[163],"performs":[164],"an":[165],"active":[166],"embryo.":[175]},"counts_by_year":[{"year":2026,"cited_by_count":3},{"year":2025,"cited_by_count":5},{"year":2024,"cited_by_count":2},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":4},{"year":2021,"cited_by_count":3},{"year":2020,"cited_by_count":3},{"year":2019,"cited_by_count":2},{"year":2018,"cited_by_count":4},{"year":2017,"cited_by_count":7},{"year":2016,"cited_by_count":1},{"year":2015,"cited_by_count":2},{"year":2014,"cited_by_count":1},{"year":2013,"cited_by_count":2},{"year":2012,"cited_by_count":2}],"updated_date":"2026-11-03T10:50:19.383937","created_date":"2016-06-24T00:00:00"}