{"id":"https://openalex.org/W2134129186","doi":"https://doi.org/10.1523/jneurosci.16-09-03067.1996","title":"Evolution of Directional Preferences in the Supplementary Eye Field during Acquisition of Conditional Oculomotor Associations","display_name":"Evolution of Directional Preferences in the Supplementary Eye Field during Acquisition of Conditional Oculomotor Associations","publication_year":1996,"publication_date":"1996-05-01","ids":{"openalex":"https://openalex.org/W2134129186","doi":"https://doi.org/10.1523/jneurosci.16-09-03067.1996","mag":"2134129186","pmid":"https://pubmed.ncbi.nlm.nih.gov/8622136","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/6579060"},"language":"en","primary_location":{"id":"doi:10.1523/jneurosci.16-09-03067.1996","doi":"https://doi.org/10.1523/jneurosci.16-09-03067.1996","is_oa":true,"landing_page_url":"https://doi.org/10.1523/jneurosci.16-09-03067.1996","pdf_url":"https://www.jneurosci.org/content/jneuro/16/9/3067.full.pdf","source":{"id":"https://openalex.org/S5555990","display_name":"Journal of Neuroscience","issn_l":"0270-6474","issn":["0270-6474","1529-2401"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-b","doyens","jufo-3","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319739","host_organization_name":"Society for Neuroscience","host_organization_lineage":["https://openalex.org/P4310319739"],"host_organization_lineage_names":["Society for Neuroscience"],"type":"journal"},"license":"cc-by-nc-sa","license_id":"https://openalex.org/licenses/cc-by-nc-sa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of Neuroscience","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://www.jneurosci.org/content/jneuro/16/9/3067.full.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5058310837","display_name":"Longtang L. Chen","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210158500","display_name":"National Institute of Mental Health","ror":"https://ror.org/04xeg9z08","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210158500"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Longtang L. Chen","raw_affiliation_strings":["Laboratory of Neurophysiology, National Institute of Mental Health, Poolesville, Maryland 20837"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory of Neurophysiology, National Institute of Mental Health, Poolesville, Maryland 20837","institution_ids":["https://openalex.org/I4210158500"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5112246287","display_name":"Steven P. Wise","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210158500","display_name":"National Institute of Mental Health","ror":"https://ror.org/04xeg9z08","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210158500"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Steven P. Wise","raw_affiliation_strings":["Laboratory of Neurophysiology, National Institute of Mental Health, Poolesville, Maryland 20837"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory of Neurophysiology, National Institute of Mental Health, Poolesville, Maryland 20837","institution_ids":["https://openalex.org/I4210158500"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I4210158500"],"apc_list":null,"apc_paid":null,"fwci":2.989,"has_fulltext":true,"cited_by_count":112,"citation_normalized_percentile":{"value":0.9181796,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":88,"max":99},"biblio":{"volume":"16","issue":"9","first_page":"3067","last_page":"3081"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10982","display_name":"Motor Control and Adaptation","score":0.7807999849319458,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10982","display_name":"Motor Control and Adaptation","score":0.7807999849319458,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10427","display_name":"Visual perception and processing mechanisms","score":0.16329999268054962,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10448","display_name":"Memory and Neural Mechanisms","score":0.020600000396370888,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/supplementary-eye-field","display_name":"supplementary eye field","score":0.9990000128746033},{"id":"https://openalex.org/keywords/preferred-direction","display_name":"preferred direction","score":0.7409999966621399},{"id":"https://openalex.org/keywords/saccades","display_name":"saccades","score":0.7789999842643738},{"id":"https://openalex.org/keywords/direction-selectivity","display_name":"direction selectivity","score":0.7590000033378601},{"id":"https://openalex.org/keywords/premotor-cortex","display_name":"premotor cortex","score":0.7049999833106995}],"concepts":[{"id":"https://openalex.org/C2779524336","wikidata":"https://www.wikidata.org/wiki/Q369503","display_name":"Saccade","level":3,"score":0.7508748769760132},{"id":"https://openalex.org/C30181142","wikidata":"https://www.wikidata.org/wiki/Q865103","display_name":"Foveal","level":3,"score":0.6469581127166748},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.6457927227020264},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.641019344329834},{"id":"https://openalex.org/C146249460","wikidata":"https://www.wikidata.org/wiki/Q2914991","display_name":"Fixation (population genetics)","level":3,"score":0.6119521260261536},{"id":"https://openalex.org/C2779918689","wikidata":"https://www.wikidata.org/wiki/Q3771842","display_name":"Stimulus (psychology)","level":2,"score":0.5471673011779785},{"id":"https://openalex.org/C11054436","wikidata":"https://www.wikidata.org/wiki/Q7396580","display_name":"Saccadic masking","level":3,"score":0.4924789369106293},{"id":"https://openalex.org/C153050134","wikidata":"https://www.wikidata.org/wiki/Q760256","display_name":"Eye movement","level":2,"score":0.4586058557033539},{"id":"https://openalex.org/C46312422","wikidata":"https://www.wikidata.org/wiki/Q11024","display_name":"Communication","level":1,"score":0.3204411268234253},{"id":"https://openalex.org/C180747234","wikidata":"https://www.wikidata.org/wiki/Q23373","display_name":"Cognitive psychology","level":1,"score":0.29715394973754883},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.1014176607131958},{"id":"https://openalex.org/C118487528","wikidata":"https://www.wikidata.org/wiki/Q161437","display_name":"Ophthalmology","level":1,"score":0.0817767083644867},{"id":"https://openalex.org/C2908647359","wikidata":"https://www.wikidata.org/wiki/Q2625603","display_name":"Population","level":2,"score":0.07743129134178162},{"id":"https://openalex.org/C2780827179","wikidata":"https://www.wikidata.org/wiki/Q422001","display_name":"Retinal","level":2,"score":0.0},{"id":"https://openalex.org/C99454951","wikidata":"https://www.wikidata.org/wiki/Q932068","display_name":"Environmental health","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001522","descriptor_name":"Behavior, Animal","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003213","descriptor_name":"Conditioning, Psychological","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D005625","descriptor_name":"Frontal Lobe","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":false},{"descriptor_ui":"D005625","descriptor_name":"Frontal Lobe","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D007858","descriptor_name":"Learning","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D008253","descriptor_name":"Macaca mulatta","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009474","descriptor_name":"Neurons","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D009799","descriptor_name":"Ocular Physiological Phenomena","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D009801","descriptor_name":"Oculomotor Muscles","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D010775","descriptor_name":"Photic Stimulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012438","descriptor_name":"Saccades","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1523/jneurosci.16-09-03067.1996","doi":"https://doi.org/10.1523/jneurosci.16-09-03067.1996","is_oa":true,"landing_page_url":"https://doi.org/10.1523/jneurosci.16-09-03067.1996","pdf_url":"https://www.jneurosci.org/content/jneuro/16/9/3067.full.pdf","source":{"id":"https://openalex.org/S5555990","display_name":"Journal of Neuroscience","issn_l":"0270-6474","issn":["0270-6474","1529-2401"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-b","doyens","jufo-3","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319739","host_organization_name":"Society for Neuroscience","host_organization_lineage":["https://openalex.org/P4310319739"],"host_organization_lineage_names":["Society for Neuroscience"],"type":"journal"},"license":"cc-by-nc-sa","license_id":"https://openalex.org/licenses/cc-by-nc-sa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of Neuroscience","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:6579060","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/6579060","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"J Neurosci","raw_type":"Text"},{"id":"pmid:8622136","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/8622136","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of neuroscience : the official journal of the Society for Neuroscience","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.1523/jneurosci.16-09-03067.1996","doi":"https://doi.org/10.1523/jneurosci.16-09-03067.1996","is_oa":true,"landing_page_url":"https://doi.org/10.1523/jneurosci.16-09-03067.1996","pdf_url":"https://www.jneurosci.org/content/jneuro/16/9/3067.full.pdf","source":{"id":"https://openalex.org/S5555990","display_name":"Journal of Neuroscience","issn_l":"0270-6474","issn":["0270-6474","1529-2401"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-b","doyens","jufo-3","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319739","host_organization_name":"Society for Neuroscience","host_organization_lineage":["https://openalex.org/P4310319739"],"host_organization_lineage_names":["Society for Neuroscience"],"type":"journal"},"license":"cc-by-nc-sa","license_id":"https://openalex.org/licenses/cc-by-nc-sa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of Neuroscience","raw_type":"journal-article"},"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2134129186.pdf","grobid_xml":"https://content.openalex.org/works/W2134129186.grobid-xml"},"referenced_works_count":69,"referenced_works":["https://openalex.org/W58303134","https://openalex.org/W120040297","https://openalex.org/W205709341","https://openalex.org/W1225653330","https://openalex.org/W1487392737","https://openalex.org/W1576057187","https://openalex.org/W1576630622","https://openalex.org/W1599180479","https://openalex.org/W1606898722","https://openalex.org/W1812033619","https://openalex.org/W1815501369","https://openalex.org/W1857829393","https://openalex.org/W1859517329","https://openalex.org/W1904024272","https://openalex.org/W1957364793","https://openalex.org/W1963811045","https://openalex.org/W1968996221","https://openalex.org/W1969271919","https://openalex.org/W1981613511","https://openalex.org/W1983475092","https://openalex.org/W1985307407","https://openalex.org/W1987620178","https://openalex.org/W1988184428","https://openalex.org/W1997036706","https://openalex.org/W2001471448","https://openalex.org/W2001831888","https://openalex.org/W2002664886","https://openalex.org/W2007996084","https://openalex.org/W2017870412","https://openalex.org/W2019800929","https://openalex.org/W2021181097","https://openalex.org/W2033435873","https://openalex.org/W2033676882","https://openalex.org/W2042254755","https://openalex.org/W2042550905","https://openalex.org/W2044193518","https://openalex.org/W2046260226","https://openalex.org/W2051772022","https://openalex.org/W2054338439","https://openalex.org/W2063379973","https://openalex.org/W2064601549","https://openalex.org/W2076145339","https://openalex.org/W2079755469","https://openalex.org/W2082333434","https://openalex.org/W2084793648","https://openalex.org/W2087016108","https://openalex.org/W2087376184","https://openalex.org/W2087809883","https://openalex.org/W2087840119","https://openalex.org/W2091485168","https://openalex.org/W2111637278","https://openalex.org/W2115170095","https://openalex.org/W2122502962","https://openalex.org/W2135959269","https://openalex.org/W2156567212","https://openalex.org/W2165873177","https://openalex.org/W2212571243","https://openalex.org/W2264537496","https://openalex.org/W2309990366","https://openalex.org/W2336932976","https://openalex.org/W2411927066","https://openalex.org/W2413200703","https://openalex.org/W2416722675","https://openalex.org/W2430664269","https://openalex.org/W2496183737","https://openalex.org/W2503360563","https://openalex.org/W2758264073","https://openalex.org/W2796985193","https://openalex.org/W4232795187"],"related_works":["https://openalex.org/W2417967864","https://openalex.org/W1225653330","https://openalex.org/W2050499848","https://openalex.org/W2081365993","https://openalex.org/W1979357097","https://openalex.org/W2402051274","https://openalex.org/W2073304852","https://openalex.org/W2192220759","https://openalex.org/W1481294305","https://openalex.org/W2204693280"],"abstract_inverted_index":{"We":[0],"assessed":[1],"the":[2,55,71,77,113,115,158,165,170,192,233],"preferred":[3],"directions":[4],"(PDs)":[5],"of":[6,21,94,135,172],"supplementary":[7],"eye":[8,24],"field":[9],"(SEF)":[10],"neurons":[11],"during":[12,91,132],"conditional":[13],"visuomotor":[14],"learning.":[15,92],"Monkeys":[16],"learned":[17,74],"to":[18,28,75,174],"select":[19,76],"one":[20,45],"four":[22,68],"saccadic":[23],"movements":[25],"in":[26,217],"response":[27],"a":[29,145,214,223],"foveal":[30],"instruction":[31],"stimulus":[32],"(IS).":[33],"ISs":[34,60,150,156],"were":[35,130,139],"either":[36,121],"familiar":[37,41,103,116,155,178],"or":[38,52,124],"novel.":[39],"Each":[40],"IS":[42,87,104,117,179],"reliably":[43],"evoked":[44],"saccade:":[46],"7":[47],"degrees":[48],"left,":[49],"right,":[50],"up,":[51],"down":[53],"form":[54],"central":[56],"fixation":[57],"point.":[58],"Novel":[59],"initially":[61,184],"triggered":[62],"virtually":[63],"random":[64],"responses":[65,231],"among":[66],"those":[67],"possibilities,":[69],"but":[70,106,137,205],"monkeys":[72],"ultimately":[73],"instructed":[78],"saccade.":[79],"As":[80],"reported":[81],"previously,":[82],"activity":[83,118],"rates":[84],"on":[85,102],"novel":[86,149],"trials":[88],"significantly":[89],"changed":[90],"Some":[93],"these":[95],"cells":[96,199],"(learning-dependent)":[97],"also":[98],"have":[99],"significant":[100,203],"modulation":[101],"trials,":[105],"others":[107],"(learning-selective)":[108],"lack":[109],"such":[110],"activity.":[111],"Of":[112],"former,":[114],"can":[119],"be":[120],"directionally":[122],"selective":[123],"omnidirectional.":[125],"For":[126],"most":[127],"neurons,":[128],"PDs":[129,186,219],"apparent":[131],"all":[133],"phases":[134],"learning,":[136,189],"they":[138],"rarely":[140],"constant.":[141],"Only":[142],"infrequently":[143],"did":[144],"neuron's":[146],"PD":[147,166],"for":[148,154,177],"closely":[151],"match":[152],"that":[153,176,220],"throughout":[157],"learning":[159,173,209],"process.":[160],"In":[161,181],"directional":[162],"learning-dependent":[163],"cells,":[164,183],"usually":[167],"reoriented":[168],"near":[169],"end":[171],"resemble":[175],"trials.":[180],"omnidirectional":[182],"evident":[185],"dissipated":[187],"with":[188,202],"even":[190],"as":[191,208],"cell":[193],"became":[194,206],"more":[195],"strongly":[196],"modulated.":[197],"Learning-selective":[198],"typically":[200],"began":[201],"PDs,":[204],"unmodulated":[207],"progressed.":[210],"Our":[211],"findings":[212],"show":[213],"pervasive":[215],"lability":[216],"SEF":[218],"may":[221],"reflect":[222],"flexible":[224],"and":[225,230],"rapid":[226],"remapping":[227],"between":[228],"inputs":[229],"within":[232],"premotor":[234],"cortical":[235],"network.":[236]},"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":2},{"year":2022,"cited_by_count":2},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":3},{"year":2019,"cited_by_count":2},{"year":2018,"cited_by_count":1},{"year":2017,"cited_by_count":1},{"year":2016,"cited_by_count":1},{"year":2015,"cited_by_count":7},{"year":2014,"cited_by_count":4},{"year":2013,"cited_by_count":3},{"year":2012,"cited_by_count":3}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}