{"id":"https://openalex.org/W2134100561","doi":"https://doi.org/10.1194/jlr.m400373-jlr200","title":"Adiponectin promotes adipocyte differentiation, insulin sensitivity, and lipid accumulation","display_name":"Adiponectin promotes adipocyte differentiation, insulin sensitivity, and lipid accumulation","publication_year":2005,"publication_date":"2005-04-17","ids":{"openalex":"https://openalex.org/W2134100561","doi":"https://doi.org/10.1194/jlr.m400373-jlr200","mag":"2134100561","pmid":"https://pubmed.ncbi.nlm.nih.gov/15834118"},"language":"en","primary_location":{"id":"doi:10.1194/jlr.m400373-jlr200","doi":"https://doi.org/10.1194/jlr.m400373-jlr200","is_oa":true,"landing_page_url":"https://doi.org/10.1194/jlr.m400373-jlr200","pdf_url":null,"source":{"id":"https://openalex.org/S11400418","display_name":"Journal of Lipid Research","issn_l":"0022-2275","issn":["0022-2275","1539-7262"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-140","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Lipid Research","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://doi.org/10.1194/jlr.m400373-jlr200","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5100526794","display_name":"Yuchang Fu","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I32389192","display_name":"University of Alabama at Birmingham","ror":"https://ror.org/008s83205","country_code":"US","type":"education","lineage":["https://openalex.org/I32389192"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Yuchang Fu","raw_affiliation_strings":["Department of Nutrition Sciences, University of Alabama at Birmingham, Birmingham, AL 35294-3360, USA. yfu@uab.edu","Department of Nutrition Sciences, University of Alabama at Birmingham, Birmingham, AL 35294-3360"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Nutrition Sciences, University of Alabama at Birmingham, Birmingham, AL 35294-3360, USA. yfu@uab.edu","institution_ids":["https://openalex.org/I32389192"]},{"raw_affiliation_string":"Department of Nutrition Sciences, University of Alabama at Birmingham, Birmingham, AL 35294-3360","institution_ids":["https://openalex.org/I32389192"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5049875631","display_name":"Nanlan Luo","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I32389192","display_name":"University of Alabama at Birmingham","ror":"https://ror.org/008s83205","country_code":"US","type":"education","lineage":["https://openalex.org/I32389192"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Nanlan Luo","raw_affiliation_strings":["Department of Nutrition Sciences, University of Alabama at Birmingham, Birmingham, AL 35294-3360"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Nutrition Sciences, University of Alabama at Birmingham, Birmingham, AL 35294-3360","institution_ids":["https://openalex.org/I32389192"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5064715409","display_name":"Richard L. Klein","orcid":"https://orcid.org/0000-0002-0316-206X","observed_orcids":["https://orcid.org/0000-0002-0316-206X"]},"institutions":[{"id":"https://openalex.org/I153297377","display_name":"Medical University of South Carolina","ror":"https://ror.org/012jban78","country_code":"US","type":"education","lineage":["https://openalex.org/I153297377"]},{"id":"https://openalex.org/I4210132004","display_name":"Ralph H. Johnson VA Medical Center","ror":"https://ror.org/030ma0n95","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1322918889","https://openalex.org/I2799886695","https://openalex.org/I4210131075","https://openalex.org/I4210132004"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Richard L. Klein","raw_affiliation_strings":["Department of Medicine, Medical University of South Carolina, and Charleston VA Medical Center, Charleston, SC 29425"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine, Medical University of South Carolina, and Charleston VA Medical Center, Charleston, SC 29425","institution_ids":["https://openalex.org/I153297377","https://openalex.org/I4210132004"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5038221659","display_name":"William Timothy Garvey","orcid":"https://orcid.org/0000-0003-0822-0860","observed_orcids":["https://orcid.org/0000-0003-0822-0860","https://orcid.org/0000-0001-8963-1412"]},"institutions":[{"id":"https://openalex.org/I32389192","display_name":"University of Alabama at Birmingham","ror":"https://ror.org/008s83205","country_code":"US","type":"education","lineage":["https://openalex.org/I32389192"]},{"id":"https://openalex.org/I4210115616","display_name":"Birmingham VA Medical Center","ror":"https://ror.org/0242qs713","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1322918889","https://openalex.org/I2799886695","https://openalex.org/I4210115616","https://openalex.org/I4210131075"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"W. Timothy Garvey","raw_affiliation_strings":["Birmingham VA Medical Center, Birmingham, AL 35233","Department of Nutrition Sciences, University of Alabama at Birmingham, Birmingham, AL 35294-3360"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Birmingham VA Medical Center, Birmingham, AL 35233","institution_ids":["https://openalex.org/I4210115616"]},{"raw_affiliation_string":"Department of Nutrition Sciences, University of Alabama at Birmingham, Birmingham, AL 35294-3360","institution_ids":["https://openalex.org/I32389192"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5100526794"],"corresponding_institution_ids":["https://openalex.org/I32389192"],"apc_list":{"value":3430,"currency":"USD","value_usd":3430},"apc_paid":{"value":3430,"currency":"USD","value_usd":3430},"fwci":18.9587,"has_fulltext":false,"cited_by_count":666,"citation_normalized_percentile":{"value":0.99580901,"is_in_top_1_percent":true,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":99,"max":100},"biblio":{"volume":"46","issue":"7","first_page":"1369","last_page":"1379"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10528","display_name":"Adipokines, Inflammation, and Metabolic Diseases","score":0.9398999810218811,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10528","display_name":"Adipokines, Inflammation, and Metabolic Diseases","score":0.9398999810218811,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11072","display_name":"Peroxisome Proliferator-Activated Receptors","score":0.03139999881386757,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11457","display_name":"Adipose Tissue and Metabolism","score":0.026599999517202377,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/adiponectin","display_name":"adiponectin","score":1.0},{"id":"https://openalex.org/keywords/adipogenic-differentiation","display_name":"adipogenesis","score":0.921999990940094},{"id":"https://openalex.org/keywords/insulin-sensitivity","display_name":"insulin sensitivity","score":0.875},{"id":"https://openalex.org/keywords/lipid-accumulation","display_name":"lipid accumulation","score":0.7979999780654907},{"id":"https://openalex.org/keywords/autocrine-signaling","display_name":"autocrine signaling","score":0.8579999804496765},{"id":"https://openalex.org/keywords/3t3-l1-fibroblasts","display_name":"3T3-L1 fibroblasts","score":0.9350000023841858},{"id":"https://openalex.org/keywords/ppargamma","display_name":"PPAR\u03b3","score":0.6420000195503235},{"id":"https://openalex.org/keywords/srebp-1c","display_name":"SREBP-1c","score":0.972000002861023},{"id":"https://openalex.org/keywords/pgc-1alpha","display_name":"PGC-1\u03b1","score":0.9890000224113464},{"id":"https://openalex.org/keywords/glut4","display_name":"GLUT4","score":0.8619999885559082},{"id":"https://openalex.org/keywords/glucose-uptake","display_name":"glucose uptake","score":0.968999981880188},{"id":"https://openalex.org/keywords/adipocyte-proliferation","display_name":"adipocyte proliferation","score":0.7350000143051147},{"id":"https://openalex.org/keywords/obesity","display_name":"obesity","score":0.5820000171661377},{"id":"https://openalex.org/keywords/type-2-diabetes","display_name":"type 2 diabetes","score":0.8519999980926514}],"concepts":[{"id":"https://openalex.org/C2776782570","wikidata":"https://www.wikidata.org/wiki/Q357439","display_name":"Adiponectin","level":4,"score":0.8702269792556763},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.8120335340499878},{"id":"https://openalex.org/C2776188179","wikidata":"https://www.wikidata.org/wiki/Q24768727","display_name":"GLUT4","level":4,"score":0.8098957538604736},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.804125189781189},{"id":"https://openalex.org/C122927707","wikidata":"https://www.wikidata.org/wiki/Q2824461","display_name":"Adipogenesis","level":3,"score":0.7805858850479126},{"id":"https://openalex.org/C2776175234","wikidata":"https://www.wikidata.org/wiki/Q357519","display_name":"Adipocyte","level":3,"score":0.7166934609413147},{"id":"https://openalex.org/C2777391703","wikidata":"https://www.wikidata.org/wiki/Q1053470","display_name":"Insulin resistance","level":3,"score":0.671251118183136},{"id":"https://openalex.org/C128240485","wikidata":"https://www.wikidata.org/wiki/Q786998","display_name":"Autocrine signalling","level":3,"score":0.6583576202392578},{"id":"https://openalex.org/C142536801","wikidata":"https://www.wikidata.org/wiki/Q4636414","display_name":"3T3-L1","level":4,"score":0.5725358128547668},{"id":"https://openalex.org/C2777866211","wikidata":"https://www.wikidata.org/wiki/Q5572349","display_name":"Glucose uptake","level":3,"score":0.5431267023086548},{"id":"https://openalex.org/C171089720","wikidata":"https://www.wikidata.org/wiki/Q193583","display_name":"Adipose tissue","level":2,"score":0.5338875651359558},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.46559083461761475},{"id":"https://openalex.org/C161573976","wikidata":"https://www.wikidata.org/wiki/Q420277","display_name":"Glucose transporter","level":3,"score":0.46026402711868286},{"id":"https://openalex.org/C2779306644","wikidata":"https://www.wikidata.org/wiki/Q2002370","display_name":"Insulin","level":2,"score":0.41361895203590393},{"id":"https://openalex.org/C2779183219","wikidata":"https://www.wikidata.org/wiki/Q4651125","display_name":"Adiponectin receptor 1","level":5,"score":0.4135863184928894},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.3794684410095215},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.1840100884437561},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.14124983549118042}],"mesh":[{"descriptor_ui":"D000071248","descriptor_name":"Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002352","descriptor_name":"Carrier Proteins","qualifier_ui":"Q000096","qualifier_name":"biosynthesis","is_major_topic":false},{"descriptor_ui":"D002454","descriptor_name":"Cell Differentiation","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D004268","descriptor_name":"DNA-Binding Proteins","qualifier_ui":"Q000096","qualifier_name":"biosynthesis","is_major_topic":false},{"descriptor_ui":"D007328","descriptor_name":"Insulin","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D007333","descriptor_name":"Insulin Resistance","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D009004","descriptor_name":"Monosaccharide Transport Proteins","qualifier_ui":"Q000096","qualifier_name":"biosynthesis","is_major_topic":false},{"descriptor_ui":"D009124","descriptor_name":"Muscle Proteins","qualifier_ui":"Q000096","qualifier_name":"biosynthesis","is_major_topic":false},{"descriptor_ui":"D014157","descriptor_name":"Transcription Factors","qualifier_ui":"Q000096","qualifier_name":"biosynthesis","is_major_topic":false},{"descriptor_ui":"D015534","descriptor_name":"Trans-Activators","qualifier_ui":"Q000096","qualifier_name":"biosynthesis","is_major_topic":false},{"descriptor_ui":"D017667","descriptor_name":"Adipocytes","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":true},{"descriptor_ui":"D017667","descriptor_name":"Adipocytes","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D022762","descriptor_name":"CCAAT-Enhancer-Binding Proteins","qualifier_ui":"Q000096","qualifier_name":"biosynthesis","is_major_topic":false},{"descriptor_ui":"D022763","descriptor_name":"CCAAT-Enhancer-Binding Protein-alpha","qualifier_ui":"Q000096","qualifier_name":"biosynthesis","is_major_topic":false},{"descriptor_ui":"D036341","descriptor_name":"Intercellular Signaling Peptides and Proteins","qualifier_ui":"Q000096","qualifier_name":"biosynthesis","is_major_topic":false},{"descriptor_ui":"D036341","descriptor_name":"Intercellular Signaling Peptides and Proteins","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D041721","descriptor_name":"3T3-L1 Cells","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D047495","descriptor_name":"PPAR gamma","qualifier_ui":"Q000096","qualifier_name":"biosynthesis","is_major_topic":false},{"descriptor_ui":"D050356","descriptor_name":"Lipid Metabolism","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D050556","descriptor_name":"Fatty Acid-Binding Proteins","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051275","descriptor_name":"Glucose Transporter Type 4","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051780","descriptor_name":"Sterol Regulatory Element Binding Protein 1","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D052242","descriptor_name":"Adiponectin","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.1194/jlr.m400373-jlr200","doi":"https://doi.org/10.1194/jlr.m400373-jlr200","is_oa":true,"landing_page_url":"https://doi.org/10.1194/jlr.m400373-jlr200","pdf_url":null,"source":{"id":"https://openalex.org/S11400418","display_name":"Journal of Lipid Research","issn_l":"0022-2275","issn":["0022-2275","1539-7262"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-140","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Lipid Research","raw_type":"journal-article"},{"id":"pmid:15834118","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/15834118","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of lipid research","raw_type":"Journal Article"},{"id":"pmh:oai:CiteSeerX.psu:10.1.1.325.6417","doi":null,"is_oa":false,"landing_page_url":"http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.325.6417","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"http://www.jlr.org/content/46/7/1369.full.pdf","raw_type":"text"},{"id":"pmh:oai:doaj.org/article:696401c1ca04405ba6f8bff617b3e72d","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/696401c1ca04405ba6f8bff617b3e72d","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Journal of Lipid Research, Vol 46, Iss 7, Pp 1369-1379 (2005)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.1194/jlr.m400373-jlr200","doi":"https://doi.org/10.1194/jlr.m400373-jlr200","is_oa":true,"landing_page_url":"https://doi.org/10.1194/jlr.m400373-jlr200","pdf_url":null,"source":{"id":"https://openalex.org/S11400418","display_name":"Journal of Lipid Research","issn_l":"0022-2275","issn":["0022-2275","1539-7262"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-140","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Lipid Research","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.8560000061988831,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G1360484089","display_name":null,"funder_award_id":"DK 38764","funder_id":"https://openalex.org/F4320337357","funder_display_name":"National Institute of Diabetes and Digestive and Kidney Diseases"},{"id":"https://openalex.org/G183423275","display_name":"Markers and Mechanisms of Vascular Disease in Diabetes","funder_award_id":"5p01hl055782-10","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G43890408","display_name":null,"funder_award_id":"P01 HL 55782","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"}],"funders":[{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337338","display_name":"National Heart, Lung, and Blood Institute","ror":"https://ror.org/012pb6c26"},{"id":"https://openalex.org/F4320337357","display_name":"National Institute of Diabetes and Digestive and Kidney Diseases","ror":"https://ror.org/00adh9b73"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":57,"referenced_works":["https://openalex.org/W1493694909","https://openalex.org/W1505315584","https://openalex.org/W1523158326","https://openalex.org/W1524321743","https://openalex.org/W1526978170","https://openalex.org/W1572402792","https://openalex.org/W1587875569","https://openalex.org/W1964588842","https://openalex.org/W1970374778","https://openalex.org/W1971082641","https://openalex.org/W1974544823","https://openalex.org/W1976981100","https://openalex.org/W1981261500","https://openalex.org/W1997978122","https://openalex.org/W2008632158","https://openalex.org/W2008941652","https://openalex.org/W2025505666","https://openalex.org/W2027090731","https://openalex.org/W2042706232","https://openalex.org/W2043419594","https://openalex.org/W2044774756","https://openalex.org/W2047695890","https://openalex.org/W2049965571","https://openalex.org/W2061144747","https://openalex.org/W2068491028","https://openalex.org/W2069497802","https://openalex.org/W2069649414","https://openalex.org/W2070538981","https://openalex.org/W2071692398","https://openalex.org/W2078853769","https://openalex.org/W2091673549","https://openalex.org/W2094115400","https://openalex.org/W2102313291","https://openalex.org/W2102677290","https://openalex.org/W2102820875","https://openalex.org/W2107865201","https://openalex.org/W2109223015","https://openalex.org/W2109238092","https://openalex.org/W2117125046","https://openalex.org/W2120688902","https://openalex.org/W2123652234","https://openalex.org/W2127797209","https://openalex.org/W2132681327","https://openalex.org/W2135298791","https://openalex.org/W2139801418","https://openalex.org/W2149703192","https://openalex.org/W2155846381","https://openalex.org/W2156260257","https://openalex.org/W2164015929","https://openalex.org/W2166370133","https://openalex.org/W2169799551","https://openalex.org/W2170607175","https://openalex.org/W2336648847","https://openalex.org/W4234150766","https://openalex.org/W4321162519","https://openalex.org/W6678921290","https://openalex.org/W6703503933"],"related_works":["https://openalex.org/W1836745624","https://openalex.org/W1965068894","https://openalex.org/W2099843805","https://openalex.org/W233486853","https://openalex.org/W2096429786","https://openalex.org/W7100916124","https://openalex.org/W2067348038","https://openalex.org/W2071497566","https://openalex.org/W2018937378","https://openalex.org/W1546083133"],"abstract_inverted_index":{"Adiponectin":[0],"is":[1],"secreted":[2],"from":[3,186],"adipocytes,":[4,32,125,189],"and":[5,20,53,78,85,103,106,115,130,158,184,197,201],"low":[6],"circulating":[7],"levels":[8],"have":[9,48],"been":[10],"epidemiologically":[11],"associated":[12],"with":[13,59,67,135],"obesity,":[14],"insulin":[15,202],"resistance,":[16],"type":[17],"2":[18],"diabetes,":[19],"cardiovascular":[21],"disease.":[22],"To":[23],"investigate":[24],"whether":[25],"adiponectin":[26,36,47,69,139,173],"could":[27],"exert":[28],"autocrine":[29,176],"effects":[30],"in":[31,38,178,209],"we":[33],"expressed":[34],"the":[35,163,205],"gene":[37,87,156,192],"3T3-L1":[39,44],"fibroblasts.":[40],"We":[41],"observed":[42,71],"that":[43],"fibroblasts":[45],"expressing":[46],"a":[49,169],"fast":[50],"growth":[51],"phase":[52],"reach":[54],"confluence":[55],"more":[56,76,83,129],"rapidly":[57],"compared":[58,134],"control":[60,136],"cells":[61,66,127],"or":[62],"LacZ-transduced":[63],"cells.":[64,137],"Furthermore,":[65],"overexpressed":[68],"were":[70],"to":[72,143,162],"differentiate":[73],"into":[74,188],"adipocytes":[75],"rapidly,":[77],"during":[79],"adipogenesis,":[80,196],"they":[81],"exhibited":[82],"prolonged":[84],"robust":[86],"expression":[88,157,193],"for":[89,172,195],"related":[90],"transcriptional":[91],"factors,":[92],"CCAAT/enhancer":[93],"binding":[94,111],"protein":[95,112],"alpha":[96],"(C/EBP2),":[97],"peroxisome":[98],"proliferator-activated":[99],"receptor":[100],"gamma":[101],"(PPARgamma),":[102],"adipocyte":[104],"determination":[105],"differentiation":[107,185],"factor":[108,177],"1/sterol-regulatory":[109],"element":[110],"1c":[113],"(ADD1/SREBP1c)":[114],"earlier":[116],"suppression":[117],"of":[118,204],"PPARgamma":[119],"coactivator-1alpha":[120],"(PGC-1alpha).":[121],"In":[122],"fully":[123],"differentiated":[124],"adiponectin-overexpressing":[126],"accumulated":[128],"larger":[131],"lipid":[132,199],"droplets":[133],"Also,":[138],"increased":[140,151,159],"insulin's":[141],"ability":[142],"maximally":[144],"stimulate":[145],"glucose":[146,152,206],"uptake":[147],"by":[148],"78%":[149],"through":[150],"transporter":[153],"4":[154],"(GLUT4)":[155],"GLUT4":[160],"recruitment":[161],"plasma":[164],"membrane.":[165],"These":[166],"data":[167],"suggest":[168],"new":[170],"role":[171],"as":[174],"an":[175],"adipose":[179],"tissues:":[180],"promoting":[181],"cell":[182],"proliferation":[183],"preadipocytes":[187],"augmenting":[190],"programmed":[191],"responsible":[194],"increasing":[198],"content":[200],"responsiveness":[203],"transport":[207],"system":[208],"adipocytes.":[210]},"counts_by_year":[{"year":2026,"cited_by_count":18},{"year":2025,"cited_by_count":25},{"year":2024,"cited_by_count":26},{"year":2023,"cited_by_count":40},{"year":2022,"cited_by_count":42},{"year":2021,"cited_by_count":44},{"year":2020,"cited_by_count":37},{"year":2019,"cited_by_count":32},{"year":2018,"cited_by_count":35},{"year":2017,"cited_by_count":30},{"year":2016,"cited_by_count":35},{"year":2015,"cited_by_count":30},{"year":2014,"cited_by_count":37},{"year":2013,"cited_by_count":34},{"year":2012,"cited_by_count":31}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}