{"id":"https://openalex.org/W2134033459","doi":"https://doi.org/10.1523/jneurosci.10-10-03247.1990","title":"Hypothalamic-pituitary-adrenal activity in aged, cognitively impaired and cognitively unimpaired rats","display_name":"Hypothalamic-pituitary-adrenal activity in aged, cognitively impaired and cognitively unimpaired rats","publication_year":1990,"publication_date":"1990-10-01","ids":{"openalex":"https://openalex.org/W2134033459","doi":"https://doi.org/10.1523/jneurosci.10-10-03247.1990","mag":"2134033459","pmid":"https://pubmed.ncbi.nlm.nih.gov/2170594","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/6570181"},"language":"en","primary_location":{"id":"doi:10.1523/jneurosci.10-10-03247.1990","doi":"https://doi.org/10.1523/jneurosci.10-10-03247.1990","is_oa":true,"landing_page_url":"https://doi.org/10.1523/jneurosci.10-10-03247.1990","pdf_url":"https://www.jneurosci.org/content/jneuro/10/10/3247.full.pdf","source":{"id":"https://openalex.org/S5555990","display_name":"Journal of Neuroscience","issn_l":"0270-6474","issn":["0270-6474","1529-2401"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-b","doyens","jufo-3","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319739","host_organization_name":"Society for Neuroscience","host_organization_lineage":["https://openalex.org/P4310319739"],"host_organization_lineage_names":["Society for Neuroscience"],"type":"journal"},"license":"cc-by-nc-sa","license_id":"https://openalex.org/licenses/cc-by-nc-sa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of Neuroscience","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://www.jneurosci.org/content/jneuro/10/10/3247.full.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5136547857","display_name":"Amalia Mary Issa","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2799434747","display_name":"Douglas Mental Health University Institute","ror":"https://ror.org/05dk2r620","country_code":"CA","type":"healthcare","lineage":["https://openalex.org/I2799434747"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"AM Issa","raw_affiliation_strings":["Developmental Neuroendocrinology Laboratory, Douglas Hospital, Research Centre, Montreal, Quebec, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Developmental Neuroendocrinology Laboratory, Douglas Hospital, Research Centre, Montreal, Quebec, Canada","institution_ids":["https://openalex.org/I2799434747"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5040676135","display_name":"Wayne B. Rowe","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2799434747","display_name":"Douglas Mental Health University Institute","ror":"https://ror.org/05dk2r620","country_code":"CA","type":"healthcare","lineage":["https://openalex.org/I2799434747"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"W Rowe","raw_affiliation_strings":["Developmental Neuroendocrinology Laboratory, Douglas Hospital, Research Centre, Montreal, Quebec, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Developmental Neuroendocrinology Laboratory, Douglas Hospital, Research Centre, Montreal, Quebec, Canada","institution_ids":["https://openalex.org/I2799434747"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5004968642","display_name":"Serge G. Gauthier","orcid":"https://orcid.org/0000-0003-4272-3330","observed_orcids":["https://orcid.org/0000-0003-4272-3330"]},"institutions":[{"id":"https://openalex.org/I2799434747","display_name":"Douglas Mental Health University Institute","ror":"https://ror.org/05dk2r620","country_code":"CA","type":"healthcare","lineage":["https://openalex.org/I2799434747"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"S Gauthier","raw_affiliation_strings":["Developmental Neuroendocrinology Laboratory, Douglas Hospital, Research Centre, Montreal, Quebec, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Developmental Neuroendocrinology Laboratory, Douglas Hospital, Research Centre, Montreal, Quebec, Canada","institution_ids":["https://openalex.org/I2799434747"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5111938462","display_name":"MJ Meaney","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2799434747","display_name":"Douglas Mental Health University Institute","ror":"https://ror.org/05dk2r620","country_code":"CA","type":"healthcare","lineage":["https://openalex.org/I2799434747"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"MJ Meaney","raw_affiliation_strings":["Developmental Neuroendocrinology Laboratory, Douglas Hospital, Research Centre, Montreal, Quebec, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Developmental Neuroendocrinology Laboratory, Douglas Hospital, Research Centre, Montreal, Quebec, Canada","institution_ids":["https://openalex.org/I2799434747"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I2799434747"],"apc_list":null,"apc_paid":null,"fwci":5.7226,"has_fulltext":true,"cited_by_count":439,"citation_normalized_percentile":{"value":0.97267081,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":95,"max":100},"biblio":{"volume":"10","issue":"10","first_page":"3247","last_page":"3254"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10529","display_name":"Stress Responses and Cortisol","score":0.9945999979972839,"subfield":{"id":"https://openalex.org/subfields/2802","display_name":"Behavioral Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10529","display_name":"Stress Responses and Cortisol","score":0.9945999979972839,"subfield":{"id":"https://openalex.org/subfields/2802","display_name":"Behavioral Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10448","display_name":"Memory and Neural Mechanisms","score":0.0017000000225380063,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12421","display_name":"Adrenal Hormones and Disorders","score":0.0005000000237487257,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/hypothalamic-pituitary-adrenal-axis","display_name":"hypothalamic-pituitary-adrenal axis","score":0.996999979019165},{"id":"https://openalex.org/keywords/aging","display_name":"aging","score":0.8759999871253967},{"id":"https://openalex.org/keywords/cognitive-impairment","display_name":"cognitive impairment","score":0.9169999957084656},{"id":"https://openalex.org/keywords/spatial-memory","display_name":"spatial memory","score":0.7440000176429749},{"id":"https://openalex.org/keywords/hippocampal-neuronal-loss","display_name":"hippocampal neuronal loss","score":0.847000002861023},{"id":"https://openalex.org/keywords/acth","display_name":"ACTH","score":0.8100000023841858},{"id":"https://openalex.org/keywords/corticosterone","display_name":"corticosterone","score":0.9990000128746033},{"id":"https://openalex.org/keywords/glucocorticoids","display_name":"glucocorticoids","score":0.9269999861717224},{"id":"https://openalex.org/keywords/restraint-stress","display_name":"restraint stress","score":0.8920000195503235},{"id":"https://openalex.org/keywords/long-evans-rats","display_name":"Long-Evans rats","score":0.8180000185966492},{"id":"https://openalex.org/keywords/hippocampal-pathology","display_name":"hippocampal pathology","score":0.7940000295639038}],"concepts":[{"id":"https://openalex.org/C2780352252","wikidata":"https://www.wikidata.org/wiki/Q422543","display_name":"Corticosterone","level":3,"score":0.8286063075065613},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.7209741473197937},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.7142692804336548},{"id":"https://openalex.org/C148762608","wikidata":"https://www.wikidata.org/wiki/Q3748185","display_name":"Hippocampal formation","level":2,"score":0.6629371047019958},{"id":"https://openalex.org/C2780841215","wikidata":"https://www.wikidata.org/wiki/Q422549","display_name":"Glucocorticoid","level":2,"score":0.6549216508865356},{"id":"https://openalex.org/C2781161787","wikidata":"https://www.wikidata.org/wiki/Q48360","display_name":"Hippocampus","level":2,"score":0.6277154684066772},{"id":"https://openalex.org/C44752575","wikidata":"https://www.wikidata.org/wiki/Q1417562","display_name":"Morris water navigation task","level":3,"score":0.5337138175964355},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.5198783874511719},{"id":"https://openalex.org/C2778024521","wikidata":"https://www.wikidata.org/wiki/Q55639806","display_name":"Basal (medicine)","level":3,"score":0.5162432193756104},{"id":"https://openalex.org/C2908647359","wikidata":"https://www.wikidata.org/wiki/Q2625603","display_name":"Population","level":2,"score":0.42259329557418823},{"id":"https://openalex.org/C125370674","wikidata":"https://www.wikidata.org/wiki/Q1527480","display_name":"Stressor","level":2,"score":0.4127139151096344},{"id":"https://openalex.org/C2780546910","wikidata":"https://www.wikidata.org/wiki/Q185690","display_name":"Adrenocorticotropic hormone","level":3,"score":0.4112514853477478},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.3239084780216217},{"id":"https://openalex.org/C71315377","wikidata":"https://www.wikidata.org/wiki/Q11364","display_name":"Hormone","level":2,"score":0.25575751066207886},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.20605745911598206},{"id":"https://openalex.org/C2779306644","wikidata":"https://www.wikidata.org/wiki/Q2002370","display_name":"Insulin","level":2,"score":0.0},{"id":"https://openalex.org/C99454951","wikidata":"https://www.wikidata.org/wiki/Q932068","display_name":"Environmental health","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000311","descriptor_name":"Adrenal Glands","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":true},{"descriptor_ui":"D000324","descriptor_name":"Adrenocorticotropic Hormone","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D000375","descriptor_name":"Aging","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002940","descriptor_name":"Circadian Rhythm","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003072","descriptor_name":"Cognition Disorders","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D003072","descriptor_name":"Cognition Disorders","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":true},{"descriptor_ui":"D003345","descriptor_name":"Corticosterone","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D006624","descriptor_name":"Hippocampus","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D007031","descriptor_name":"Hypothalamus","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":true},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009474","descriptor_name":"Neurons","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D010902","descriptor_name":"Pituitary Gland","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":true},{"descriptor_ui":"D011965","descriptor_name":"Receptors, Glucocorticoid","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D013312","descriptor_name":"Stress, Physiological","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D051381","descriptor_name":"Rats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.1523/jneurosci.10-10-03247.1990","doi":"https://doi.org/10.1523/jneurosci.10-10-03247.1990","is_oa":true,"landing_page_url":"https://doi.org/10.1523/jneurosci.10-10-03247.1990","pdf_url":"https://www.jneurosci.org/content/jneuro/10/10/3247.full.pdf","source":{"id":"https://openalex.org/S5555990","display_name":"Journal of Neuroscience","issn_l":"0270-6474","issn":["0270-6474","1529-2401"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-b","doyens","jufo-3","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319739","host_organization_name":"Society for Neuroscience","host_organization_lineage":["https://openalex.org/P4310319739"],"host_organization_lineage_names":["Society for Neuroscience"],"type":"journal"},"license":"cc-by-nc-sa","license_id":"https://openalex.org/licenses/cc-by-nc-sa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of Neuroscience","raw_type":"journal-article"},{"id":"pmh:oai:europepmc.org:5770001","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/6570181","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},{"id":"pmid:2170594","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/2170594","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of neuroscience : the official journal of the Society for Neuroscience","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:6570181","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC6570181/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"J Neurosci","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1523/jneurosci.10-10-03247.1990","doi":"https://doi.org/10.1523/jneurosci.10-10-03247.1990","is_oa":true,"landing_page_url":"https://doi.org/10.1523/jneurosci.10-10-03247.1990","pdf_url":"https://www.jneurosci.org/content/jneuro/10/10/3247.full.pdf","source":{"id":"https://openalex.org/S5555990","display_name":"Journal of Neuroscience","issn_l":"0270-6474","issn":["0270-6474","1529-2401"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-b","doyens","jufo-3","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319739","host_organization_name":"Society for Neuroscience","host_organization_lineage":["https://openalex.org/P4310319739"],"host_organization_lineage_names":["Society for Neuroscience"],"type":"journal"},"license":"cc-by-nc-sa","license_id":"https://openalex.org/licenses/cc-by-nc-sa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of Neuroscience","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.9537000060081482}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320324195","display_name":"Medical Research Council Canada","ror":"https://ror.org/01gavpb45"},{"id":"https://openalex.org/F4320334626","display_name":"Medical Research Council","ror":"https://ror.org/03x94j517"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2134033459.pdf","grobid_xml":"https://content.openalex.org/works/W2134033459.grobid-xml"},"referenced_works_count":46,"referenced_works":["https://openalex.org/W108965517","https://openalex.org/W203906467","https://openalex.org/W249845531","https://openalex.org/W1051312076","https://openalex.org/W1498494065","https://openalex.org/W1507370673","https://openalex.org/W1564797650","https://openalex.org/W1581116698","https://openalex.org/W1642124290","https://openalex.org/W1972278707","https://openalex.org/W1981480708","https://openalex.org/W1995549578","https://openalex.org/W1999504909","https://openalex.org/W2003050811","https://openalex.org/W2008050722","https://openalex.org/W2009613516","https://openalex.org/W2011669749","https://openalex.org/W2017169966","https://openalex.org/W2018203792","https://openalex.org/W2024255841","https://openalex.org/W2029417981","https://openalex.org/W2029470650","https://openalex.org/W2031785911","https://openalex.org/W2032281246","https://openalex.org/W2035868356","https://openalex.org/W2036587591","https://openalex.org/W2046177214","https://openalex.org/W2055238225","https://openalex.org/W2055806024","https://openalex.org/W2060841481","https://openalex.org/W2062177126","https://openalex.org/W2062815214","https://openalex.org/W2069120351","https://openalex.org/W2072536549","https://openalex.org/W2074802748","https://openalex.org/W2079993990","https://openalex.org/W2084702579","https://openalex.org/W2087676383","https://openalex.org/W2090215646","https://openalex.org/W2093500055","https://openalex.org/W2113962949","https://openalex.org/W2114256457","https://openalex.org/W2128635872","https://openalex.org/W2137374430","https://openalex.org/W2162972693","https://openalex.org/W2163815564"],"related_works":["https://openalex.org/W7033594067","https://openalex.org/W1621227824","https://openalex.org/W2058363870","https://openalex.org/W1976510055","https://openalex.org/W2004227284","https://openalex.org/W1965181353","https://openalex.org/W1920785023","https://openalex.org/W2107883305","https://openalex.org/W2068982826","https://openalex.org/W2046895321"],"abstract_inverted_index":{"There":[0],"is":[1,44],"a":[2,51,139,222],"tendency":[3],"for":[4,63],"increased":[5,179],"hypothalamic-pituitary-adrenal":[6],"(HPA)":[7],"activity":[8],"with":[9,47,196,242],"age":[10],"in":[11,18,25,50,155,168,191,235],"the":[12,15,26,35,68,112,125,156,161,163,169,192,205,209,228,231],"rat,":[13],"and":[14,31,72,99,132,149,185,200,214,246],"resulting":[16],"elevations":[17],"circulating":[19],"glucocorticoid":[20],"levels":[21,187,220,234],"have":[22],"been":[23],"implicated":[24],"occurrence":[27],"of":[28,53,75,96,111,117,124,138,141,160,178,208,230],"hippocampal":[29],"pathology":[30],"memory":[32,65],"deficits.":[33],"In":[34],"experiments":[36],"reported":[37],"here,":[38],"we":[39],"examined":[40],"whether":[41],"HPA":[42,180],"dysfunction":[43],"selectively":[45],"associated":[46],"cognitive":[48],"impairments":[49,66],"population":[52],"aged":[54,76],"rats.":[55],"Fifty-eight":[56],"23-27-month-old":[57],"male":[58],"Long-Evans":[59],"rats":[60],"were":[61,78,128,188,238],"screened":[62],"spatial":[64],"using":[67],"Morris":[69],"swim":[70],"maze,":[71],"2":[73,92],"groups":[74],"animals":[77,84,104,126,143,151,174,194,199,216,237,245],"selected;":[79],"aged,":[80,100],"cognitively":[81,101],"impaired":[82],"(AI)":[83],"whose":[85,105],"performance":[86,106],"was":[87,107,165],"significantly":[88,166,189,239],"different":[89],"(greater":[90],"than":[91,119],"SD)":[93],"from":[94],"that":[95,110],"6-month-old":[97],"controls":[98,114],"unimpaired":[102],"(AU)":[103],"comparable":[108,218],"to":[109],"young":[113,201,215],"(a":[115],"difference":[116],"less":[118],"0.5":[120],"SD).":[121],"Twenty-eight":[122],"percent":[123],"tested":[127],"designated":[129],"as":[130,134],"AI":[131,150,170,173,193,236],"20%":[133],"AU.":[135],"Histological":[136],"analysis":[137],"subset":[140],"these":[142],"showed":[144,152,175],"that,":[145],"while":[146],"both":[147,197,243],"AU":[148,198,244],"neuron":[153],"loss":[154,164],"pyramidal":[157],"cell":[158],"fields":[159],"hippocampus,":[162],"greater":[167],"animals.":[171],"The":[172,211],"clear":[176],"evidence":[177],"activity.":[181],"Thus,":[182],"basal":[183],"ACTH":[184],"corticosterone":[186,219,233],"higher":[190],"compared":[195,241],"controls,":[202],"especially":[203],"during":[204,221],"dark":[206],"phase":[207],"cycle.":[210],"AI,":[212],"AU,":[213],"exhibited":[217],"20-min":[223],"immobilization":[224],"stress;":[225],"however,":[226],"following":[227],"termination":[229],"stressor,":[232],"elevated":[240],"controls.(ABSTRACT":[247],"TRUNCATED":[248],"AT":[249],"250":[250],"WORDS)":[251]},"counts_by_year":[{"year":2026,"cited_by_count":4},{"year":2025,"cited_by_count":3},{"year":2024,"cited_by_count":5},{"year":2023,"cited_by_count":5},{"year":2022,"cited_by_count":7},{"year":2021,"cited_by_count":6},{"year":2020,"cited_by_count":10},{"year":2019,"cited_by_count":8},{"year":2018,"cited_by_count":6},{"year":2017,"cited_by_count":3},{"year":2016,"cited_by_count":11},{"year":2015,"cited_by_count":10},{"year":2014,"cited_by_count":13},{"year":2013,"cited_by_count":13},{"year":2012,"cited_by_count":14}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2016-06-24T00:00:00"}