{"id":"https://openalex.org/W21339826","doi":null,"title":"Recent approaches in the treatment of Hodgkin's lymphoma.","display_name":"Recent approaches in the treatment of Hodgkin's lymphoma.","publication_year":1999,"publication_date":"1999-01-01","ids":{"openalex":"https://openalex.org/W21339826","mag":"21339826","pmid":"https://pubmed.ncbi.nlm.nih.gov/10743718"},"language":"en","primary_location":{"id":"pmid:10743718","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/10743718","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Acta Universitatis Palackianae Olomucensis Facultatis Medicae","raw_type":"Journal Article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5091748427","display_name":"Lud\u011bk Raida","orcid":"https://orcid.org/0000-0003-4032-5793","observed_orcids":["https://orcid.org/0000-0003-4032-5793"]},"institutions":[{"id":"https://openalex.org/I4210107161","display_name":"University Hospital Olomouc","ror":"https://ror.org/01jxtne23","country_code":"CZ","type":"healthcare","lineage":["https://openalex.org/I4210107161"]}],"countries":["CZ"],"is_corresponding":true,"raw_author_name":"L Raida","raw_affiliation_strings":["Haemato-oncology Department of University Hospital, Olomouc, Czech Republic"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Haemato-oncology Department of University Hospital, Olomouc, Czech Republic","institution_ids":["https://openalex.org/I4210107161"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5091748427"],"corresponding_institution_ids":["https://openalex.org/I4210107161"],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.0033192,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"142","issue":null,"first_page":"13","last_page":"7"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10185","display_name":"Lymphoma Diagnosis and Treatment","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2734","display_name":"Pathology and Forensic Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10185","display_name":"Lymphoma Diagnosis and Treatment","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2734","display_name":"Pathology and Forensic Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11157","display_name":"Chronic Lymphocytic Leukemia Research","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10685","display_name":"Viral-associated cancers and disorders","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/hodgkin-lymphoma","display_name":"Hodgkin's disease","score":0.9879999756813049},{"id":"https://openalex.org/keywords/hodgkin-lymphoma-treatment","display_name":"Hodgkin lymphoma treatment","score":0.8489999771118164},{"id":"https://openalex.org/keywords/advanced-stage-hodgkin-lymphoma","display_name":"advanced-stage Hodgkin lymphoma","score":0.7609999775886536},{"id":"https://openalex.org/keywords/refractory-hodgkin-lymphoma","display_name":"refractory Hodgkin lymphoma","score":0.9150000214576721},{"id":"https://openalex.org/keywords/relapsed-hodgkin-lymphoma","display_name":"relapsed Hodgkin lymphoma","score":0.9580000042915344},{"id":"https://openalex.org/keywords/late-toxicity","display_name":"late toxicity","score":0.9129999876022339},{"id":"https://openalex.org/keywords/curability","display_name":"curability","score":0.640999972820282},{"id":"https://openalex.org/keywords/personalized-treatment","display_name":"personalized treatment","score":0.6729999780654907}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.7613286972045898},{"id":"https://openalex.org/C142424586","wikidata":"https://www.wikidata.org/wiki/Q7307572","display_name":"Refractory (planetary science)","level":2,"score":0.5929692983627319},{"id":"https://openalex.org/C2779338263","wikidata":"https://www.wikidata.org/wiki/Q208414","display_name":"Lymphoma","level":2,"score":0.5873720645904541},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.5636796355247498},{"id":"https://openalex.org/C177713679","wikidata":"https://www.wikidata.org/wiki/Q679690","display_name":"Intensive care medicine","level":1,"score":0.5168285965919495},{"id":"https://openalex.org/C2778384578","wikidata":"https://www.wikidata.org/wiki/Q16930687","display_name":"Therapeutic approach","level":3,"score":0.4775972366333008},{"id":"https://openalex.org/C2992779791","wikidata":"https://www.wikidata.org/wiki/Q209369","display_name":"Hodgkin lymphoma","level":3,"score":0.46561360359191895},{"id":"https://openalex.org/C2994123057","wikidata":"https://www.wikidata.org/wiki/Q1595418","display_name":"Cure rate","level":2,"score":0.44919630885124207},{"id":"https://openalex.org/C2778476748","wikidata":"https://www.wikidata.org/wiki/Q1138590","display_name":"Non-Hodgkin's lymphoma","level":3,"score":0.4107973873615265},{"id":"https://openalex.org/C143998085","wikidata":"https://www.wikidata.org/wiki/Q162555","display_name":"Oncology","level":1,"score":0.3761577606201172},{"id":"https://openalex.org/C187212893","wikidata":"https://www.wikidata.org/wiki/Q123028","display_name":"Pediatrics","level":1,"score":0.3433539867401123},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.28617119789123535},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.26365697383880615},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.0},{"id":"https://openalex.org/C87355193","wikidata":"https://www.wikidata.org/wiki/Q411","display_name":"Astrobiology","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000971","descriptor_name":"Antineoplastic Combined Chemotherapy Protocols","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D006689","descriptor_name":"Hodgkin Disease","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D006689","descriptor_name":"Hodgkin Disease","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009367","descriptor_name":"Neoplasm Staging","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016026","descriptor_name":"Bone Marrow Transplantation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016178","descriptor_name":"Granulocyte-Macrophage Colony-Stimulating Factor","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D016179","descriptor_name":"Granulocyte Colony-Stimulating Factor","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false}],"locations_count":3,"locations":[{"id":"pmid:10743718","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/10743718","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Acta Universitatis Palackianae Olomucensis Facultatis Medicae","raw_type":"Journal Article"},{"id":"pmh:oai:CiteSeerX.psu:10.1.1.386.6709","doi":null,"is_oa":false,"landing_page_url":"http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.386.6709","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"http://publib.upol.cz/~obd/fulltext/medic142/medic142-02.pdf","raw_type":"text"},{"id":"mag:21339826","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/10743718","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.98580002784729,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":159,"referenced_works":["https://openalex.org/W18139128","https://openalex.org/W24911164","https://openalex.org/W143012148","https://openalex.org/W567600908","https://openalex.org/W1493874478","https://openalex.org/W1508615370","https://openalex.org/W1524100466","https://openalex.org/W1539079695","https://openalex.org/W1543819877","https://openalex.org/W1557188549","https://openalex.org/W1833833181","https://openalex.org/W1883598689","https://openalex.org/W1912609891","https://openalex.org/W1941328144","https://openalex.org/W1942259007","https://openalex.org/W1946954093","https://openalex.org/W1963670040","https://openalex.org/W1969871517","https://openalex.org/W1974477840","https://openalex.org/W1975252442","https://openalex.org/W1977439932","https://openalex.org/W1977692905","https://openalex.org/W1979000206","https://openalex.org/W1980585568","https://openalex.org/W1982066159","https://openalex.org/W1982832359","https://openalex.org/W1983146421","https://openalex.org/W1987404007","https://openalex.org/W1990006071","https://openalex.org/W1992758263","https://openalex.org/W1995651819","https://openalex.org/W1998694690","https://openalex.org/W1998723805","https://openalex.org/W2006090844","https://openalex.org/W2006176648","https://openalex.org/W2008000328","https://openalex.org/W2011984292","https://openalex.org/W2012533128","https://openalex.org/W2015368985","https://openalex.org/W2015813712","https://openalex.org/W2016000751","https://openalex.org/W2016275544","https://openalex.org/W2016675261","https://openalex.org/W2019010012","https://openalex.org/W2020709290","https://openalex.org/W2022073687","https://openalex.org/W2022452557","https://openalex.org/W2022920751","https://openalex.org/W2026192881","https://openalex.org/W2028753384","https://openalex.org/W2030435945","https://openalex.org/W2033037565","https://openalex.org/W2035353436","https://openalex.org/W2037393234","https://openalex.org/W2038526217","https://openalex.org/W2040735204","https://openalex.org/W2041629407","https://openalex.org/W2041975801","https://openalex.org/W2044392709","https://openalex.org/W2046671502","https://openalex.org/W2046810197","https://openalex.org/W2047672885","https://openalex.org/W2048210457","https://openalex.org/W2048810699","https://openalex.org/W2054094564","https://openalex.org/W2055558717","https://openalex.org/W2056346677","https://openalex.org/W2057603597","https://openalex.org/W2059402899","https://openalex.org/W2059842681","https://openalex.org/W2060158445","https://openalex.org/W2060315217","https://openalex.org/W2060721054","https://openalex.org/W2060757154","https://openalex.org/W2062398989","https://openalex.org/W2069645348","https://openalex.org/W2071466846","https://openalex.org/W2073123649","https://openalex.org/W2075698534","https://openalex.org/W2075898541","https://openalex.org/W2077552190","https://openalex.org/W2077740101","https://openalex.org/W2079480877","https://openalex.org/W2080222060","https://openalex.org/W2080697483","https://openalex.org/W2080777873","https://openalex.org/W2081989704","https://openalex.org/W2083296004","https://openalex.org/W2083453926","https://openalex.org/W2087415640","https://openalex.org/W2088596195","https://openalex.org/W2092640147","https://openalex.org/W2095644294","https://openalex.org/W2097343040","https://openalex.org/W2099491556","https://openalex.org/W2099988673","https://openalex.org/W2100433584","https://openalex.org/W2102201601","https://openalex.org/W2102567162","https://openalex.org/W2102710759","https://openalex.org/W2103131731","https://openalex.org/W2105774523","https://openalex.org/W2107127930","https://openalex.org/W2107202569","https://openalex.org/W2107279938","https://openalex.org/W2111280086","https://openalex.org/W2112059762","https://openalex.org/W2114814282","https://openalex.org/W2115802159","https://openalex.org/W2115919161","https://openalex.org/W2117485162","https://openalex.org/W2121329320","https://openalex.org/W2121739532","https://openalex.org/W2123988464","https://openalex.org/W2124801177","https://openalex.org/W2125279249","https://openalex.org/W2125837900","https://openalex.org/W2126904020","https://openalex.org/W2127811976","https://openalex.org/W2129643432","https://openalex.org/W2131348308","https://openalex.org/W2132976876","https://openalex.org/W2133635536","https://openalex.org/W2135291160","https://openalex.org/W2137786207","https://openalex.org/W2144326223","https://openalex.org/W2145499545","https://openalex.org/W2151128757","https://openalex.org/W2154432796","https://openalex.org/W2156055060","https://openalex.org/W2156613346","https://openalex.org/W2158386563","https://openalex.org/W2158529146","https://openalex.org/W2166878789","https://openalex.org/W2180824684","https://openalex.org/W2186482588","https://openalex.org/W2240717407","https://openalex.org/W2262902984","https://openalex.org/W2266633670","https://openalex.org/W2285984220","https://openalex.org/W2289120045","https://openalex.org/W2322312023","https://openalex.org/W2399767716","https://openalex.org/W2399823141","https://openalex.org/W2405444975","https://openalex.org/W2413744602","https://openalex.org/W2425470053","https://openalex.org/W2432405843","https://openalex.org/W2432760528","https://openalex.org/W2470638563","https://openalex.org/W2472041546","https://openalex.org/W2492253140","https://openalex.org/W2517347338","https://openalex.org/W2621682113","https://openalex.org/W4235589005","https://openalex.org/W4256529254","https://openalex.org/W6603159292","https://openalex.org/W6777124403","https://openalex.org/W7046634634"],"related_works":["https://openalex.org/W4411319022","https://openalex.org/W2097591102","https://openalex.org/W1986962822","https://openalex.org/W2511893194","https://openalex.org/W2095774866","https://openalex.org/W4250553950","https://openalex.org/W2167555906","https://openalex.org/W2162233963","https://openalex.org/W2126212936","https://openalex.org/W4285392397"],"abstract_inverted_index":{"An":[0],"aim":[1],"has":[2,46],"been":[3],"to":[4,48,65,82,90,100],"find":[5],"the":[6,24,35,49,54,74,84,104,109],"optimal":[7],"therapeutic":[8,40,92],"approach":[9],"for":[10],"each":[11],"patient":[12],"suffering":[13],"from":[14],"Hodgkin's":[15],"lymphoma.":[16],"The":[17,76],"disease":[18],"with":[19],"80%":[20],"curability":[21,85],"rate":[22],"presents":[23],"great":[25],"success":[26],"of":[27,39,61,86],"clinical":[28],"oncology.":[29],"There":[30],"is":[31],"no":[32],"doubt":[33],"that":[34],"development":[36],"and":[37,96,112],"improvement":[38],"approaches":[41],"described":[42],"in":[43,53,73,94,108],"this":[44],"article":[45],"contributed":[47],"excellent":[50],"results":[51,93],"achieved":[52],"last":[55],"twenty":[56],"years.":[57],"But":[58],"a":[59],"lot":[60],"problems":[62],"still":[63],"remain":[64],"be":[66],"solved":[67],"by":[68],"haemato-oncologists":[69],"despite":[70],"such":[71],"progress":[72],"treatment.":[75],"most":[77],"important":[78],"tasks":[79],"are:":[80],"1.":[81],"increase":[83],"advanced":[87],"stages,":[88],"2.":[89],"improve":[91],"refractory":[95],"relapsing":[97],"patients,":[98],"3.":[99],"eliminate":[101],"or":[102],"decrease":[103],"late":[105],"toxicity":[106],"particularly":[107],"favourable":[110],"early":[111],"intermediate":[113],"stages.":[114]},"counts_by_year":[],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}
