{"id":"https://openalex.org/W2133704109","doi":null,"title":"Randomized trial of the effect of an integrative medicine approach to the management of asthma in adults on disease-related quality of life and pulmonary function.","display_name":"Randomized trial of the effect of an integrative medicine approach to the management of asthma in adults on disease-related quality of life and pulmonary function.","publication_year":2011,"publication_date":"2011-01-01","ids":{"openalex":"https://openalex.org/W2133704109","mag":"2133704109","pmid":"https://pubmed.ncbi.nlm.nih.gov/21614939"},"language":"en","primary_location":{"id":"pmid:21614939","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/21614939","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Alternative therapies in health and medicine","raw_type":"Journal Article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5057572097","display_name":"Benjamin Kligler","orcid":"https://orcid.org/0000-0002-6053-2602","observed_orcids":["https://orcid.org/0000-0002-6053-2602"]},"institutions":[{"id":"https://openalex.org/I1287643137","display_name":"Mount Sinai Beth Israel","ror":"https://ror.org/01742jq13","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1287643137","https://openalex.org/I1320796813"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Benjamin Kligler","raw_affiliation_strings":["Beth Israel Department of Integrative Medicine, New York, New York, USA. bkligler@chpnet.org"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Beth Israel Department of Integrative Medicine, New York, New York, USA. bkligler@chpnet.org","institution_ids":["https://openalex.org/I1287643137"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109222279","display_name":"Peter Homel","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Peter Homel","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5029964703","display_name":"Arthur E. Blank","orcid":"https://orcid.org/0000-0002-3368-0407","observed_orcids":["https://orcid.org/0000-0002-3368-0407"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Arthur E Blank","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5089542233","display_name":"Jeanne Kenney","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Jeanne Kenney","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5062888116","display_name":"Hanniel Levenson","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Hanniel Levenson","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5087304262","display_name":"Woodson C. Merrell","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Woodson Merrell","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":3.2255,"has_fulltext":false,"cited_by_count":29,"citation_normalized_percentile":{"value":0.91975258,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":88,"max":98},"biblio":{"volume":"17","issue":"1","first_page":"10","last_page":"5"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10051","display_name":"Asthma and respiratory diseases","score":0.7738999724388123,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10051","display_name":"Asthma and respiratory diseases","score":0.7738999724388123,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10902","display_name":"Complementary and Alternative Medicine Studies","score":0.20909999310970306,"subfield":{"id":"https://openalex.org/subfields/2707","display_name":"Complementary and alternative medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12647","display_name":"Traditional Chinese Medicine Studies","score":0.004000000189989805,"subfield":{"id":"https://openalex.org/subfields/2707","display_name":"Complementary and alternative medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/asthma","display_name":"asthma","score":0.9210000038146973},{"id":"https://openalex.org/keywords/integrative-medicine","display_name":"integrative medicine","score":1.0},{"id":"https://openalex.org/keywords/quality-of-life","display_name":"quality of life","score":0.8450000286102295},{"id":"https://openalex.org/keywords/lung-function","display_name":"lung function","score":0.9879999756813049},{"id":"https://openalex.org/keywords/dietary-intervention","display_name":"dietary intervention","score":0.7170000076293945},{"id":"https://openalex.org/keywords/yoga","display_name":"yoga","score":0.9160000085830688},{"id":"https://openalex.org/keywords/journaling","display_name":"journaling","score":0.9649999737739563},{"id":"https://openalex.org/keywords/fish-oil","display_name":"fish oil","score":0.8370000123977661},{"id":"https://openalex.org/keywords/vitamin-c","display_name":"vitamin C","score":0.9919999837875366},{"id":"https://openalex.org/keywords/hop-extract","display_name":"hop extract","score":0.9819999933242798},{"id":"https://openalex.org/keywords/group-intervention","display_name":"group intervention","score":0.7919999957084656},{"id":"https://openalex.org/keywords/adults","display_name":"adults","score":0.4819999933242798}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8837358355522156},{"id":"https://openalex.org/C1862650","wikidata":"https://www.wikidata.org/wiki/Q186005","display_name":"Physical therapy","level":1,"score":0.7007472515106201},{"id":"https://openalex.org/C168563851","wikidata":"https://www.wikidata.org/wiki/Q1436668","display_name":"Randomized controlled trial","level":2,"score":0.6896718740463257},{"id":"https://openalex.org/C2776042228","wikidata":"https://www.wikidata.org/wiki/Q35869","display_name":"Asthma","level":2,"score":0.6863903999328613},{"id":"https://openalex.org/C2779951463","wikidata":"https://www.wikidata.org/wiki/Q7268788","display_name":"Quality of life (healthcare)","level":2,"score":0.6859391927719116},{"id":"https://openalex.org/C75603125","wikidata":"https://www.wikidata.org/wiki/Q1877462","display_name":"Pulmonary function testing","level":2,"score":0.5218868851661682},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.31403598189353943},{"id":"https://openalex.org/C159110408","wikidata":"https://www.wikidata.org/wiki/Q121176","display_name":"Nursing","level":1,"score":0.07381969690322876}],"mesh":[{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000369","descriptor_name":"Aged, 80 and over","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000529","descriptor_name":"Complementary Therapies","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D001205","descriptor_name":"Ascorbic Acid","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D001249","descriptor_name":"Asthma","qualifier_ui":"Q000517","qualifier_name":"prevention & control","is_major_topic":false},{"descriptor_ui":"D001249","descriptor_name":"Asthma","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":true},{"descriptor_ui":"D003131","descriptor_name":"Combined Modality Therapy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004365","descriptor_name":"Drugs, Chinese Herbal","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007388","descriptor_name":"Internal Medicine","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011788","descriptor_name":"Quality of Life","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D015013","descriptor_name":"Yoga","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015438","descriptor_name":"Health Behavior","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016896","descriptor_name":"Treatment Outcome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017060","descriptor_name":"Patient Satisfaction","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018927","descriptor_name":"Anti-Asthmatic Agents","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D019317","descriptor_name":"Evidence-Based Medicine","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D055815","descriptor_name":"Young Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"pmid:21614939","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/21614939","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Alternative therapies in health and medicine","raw_type":"Journal Article"},{"id":"mag:2133704109","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/21614939","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":1.0,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Randomized Controlled Trial","id":"https://openalex.org/study-designs/randomized-controlled-trial"},{"display_name":"Clinical Trial","id":"https://openalex.org/study-designs/clinical-trial"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":42,"referenced_works":["https://openalex.org/W41175020","https://openalex.org/W1483722373","https://openalex.org/W1978550769","https://openalex.org/W1985725633","https://openalex.org/W1995017236","https://openalex.org/W1996442679","https://openalex.org/W1997673087","https://openalex.org/W2000574317","https://openalex.org/W2008150938","https://openalex.org/W2017885119","https://openalex.org/W2021206292","https://openalex.org/W2023690878","https://openalex.org/W2024585538","https://openalex.org/W2028607481","https://openalex.org/W2038975854","https://openalex.org/W2047713067","https://openalex.org/W2069676636","https://openalex.org/W2075616178","https://openalex.org/W2077320767","https://openalex.org/W2080774711","https://openalex.org/W2082270078","https://openalex.org/W2083662448","https://openalex.org/W2099969125","https://openalex.org/W2102997995","https://openalex.org/W2109724214","https://openalex.org/W2111305552","https://openalex.org/W2113991276","https://openalex.org/W2124630220","https://openalex.org/W2127584048","https://openalex.org/W2147620724","https://openalex.org/W2150630865","https://openalex.org/W2157999096","https://openalex.org/W2159448938","https://openalex.org/W2165612525","https://openalex.org/W2167165853","https://openalex.org/W2167619051","https://openalex.org/W2258263699","https://openalex.org/W2263303453","https://openalex.org/W2337602032","https://openalex.org/W2396611088","https://openalex.org/W2406016142","https://openalex.org/W2480711185"],"related_works":["https://openalex.org/W2419011727","https://openalex.org/W2903628672","https://openalex.org/W2799632724","https://openalex.org/W4399401222","https://openalex.org/W2111494890","https://openalex.org/W2185611698","https://openalex.org/W2080006682","https://openalex.org/W2073372757","https://openalex.org/W2169863824","https://openalex.org/W2460237270"],"abstract_inverted_index":{"PURPOSE:":[0],"The":[1,55,86,103],"purpose":[2],"of":[3,11,19,28,58,65,99,172],"this":[4],"study":[5],"was":[6,36,207],"to":[7,16,22,50,224],"test":[8],"the":[9,17,63,96,126,144,173,193],"effectiveness":[10],"an":[12],"integrative":[13,219],"medicine":[14,220],"approach":[15],"management":[18],"asthma":[20],"compared":[21],"standard":[23,111],"clinical":[24,32],"care":[25],"on":[26,62,170],"quality":[27],"life":[29],"(QOL)":[30],"and":[31,70,81,110,123,149,159,184,198,203],"outcomes.":[33],"METHODS:":[34],"This":[35],"a":[37,82],"prospective":[38],"parallel":[39],"group":[40,60,88],"repeated":[41],"measurement":[42],"randomized":[43,122],"design.":[44],"Participants":[45,72],"were":[46,95,121],"adults":[47,230],"aged":[48],"18":[49],"80":[51],"years":[52],"with":[53,231],"asthma.":[54,232],"intervention":[56,221],"consisted":[57],"six":[59],"sessions":[61],"use":[64],"nutritional":[66,75],"manipulation,":[67],"yoga":[68],"techniques,":[69],"journaling.":[71],"also":[73,164],"received":[74,89],"supplements:":[76],"fish":[77],"oil,":[78],"vitamin":[79],"C,":[80],"standardized":[83],"hops":[84],"extract.":[85],"control":[87],"usual":[90],"care.":[91],"Primary":[92],"outcome":[93],"measures":[94],"Asthma":[97],"Quality":[98],"Life":[100],"Questionnaire":[101],"(AQLQ),":[102],"Medical":[104],"Outcomes":[105],"Study":[106],"Short":[107],"Form-12":[108],"(SF-12),":[109],"pulmonary":[112],"function":[113],"tests":[114],"(PFTs).":[115],"RESULTS:":[116],"In":[117],"total,":[118],"154":[119],"patients":[120],"included":[124],"in":[125,192,210,212,227,229],"intention-to-treat":[127],"analysis":[128],"(77":[129],"control,":[130],"77":[131],"treatment).":[132],"Treatment":[133,162],"participants":[134,163],"showed":[135,165],"greater":[136,166],"improvement":[137,167,226],"than":[138,168],"controls":[139,169],"at":[140],"6":[141],"months":[142],"for":[143,150,196],"AQLQ":[145],"total":[146],"score":[147],"(P<.001)":[148],"three":[151,171],"subscales,":[152,175],"Activity":[153],"(P<":[154,182],"0.001),":[155],"Symptoms":[156],"(P=":[157,187,201],".02),":[158],"Emotion":[160],"(P<.001).":[161],"SF-12":[174],"Physical":[176,181,197],"functioning":[177,186],"(P=.003);":[178],"Role":[179],"limitations,":[180],".001);":[183],"Social":[185],"0.03),":[188],"as":[189,191],"well":[190],"aggregate":[194],"scores":[195],"Mental":[199],"health":[200],".003":[202],".02,":[204],"respectively).":[205],"There":[206],"no":[208],"change":[209],"PFTs":[211],"either":[213],"group.":[214],"CONCLUSION:":[215],"A":[216],"low-cost":[217],"group-oriented":[218],"can":[222],"lead":[223],"significant":[225],"QOL":[228]},"counts_by_year":[{"year":2024,"cited_by_count":1},{"year":2022,"cited_by_count":1},{"year":2019,"cited_by_count":2},{"year":2017,"cited_by_count":4},{"year":2016,"cited_by_count":3},{"year":2015,"cited_by_count":4},{"year":2014,"cited_by_count":5},{"year":2013,"cited_by_count":3},{"year":2012,"cited_by_count":5}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}