{"id":"https://openalex.org/W2133330752","doi":"https://doi.org/10.1128/jvi.61.3.743-747.1987","title":"Characterization of equine infectious anemia virus long terminal repeat","display_name":"Characterization of equine infectious anemia virus long terminal repeat","publication_year":1987,"publication_date":"1987-03-01","ids":{"openalex":"https://openalex.org/W2133330752","doi":"https://doi.org/10.1128/jvi.61.3.743-747.1987","mag":"2133330752","pmid":"https://pubmed.ncbi.nlm.nih.gov/3027401","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/254015"},"language":"en","primary_location":{"id":"doi:10.1128/jvi.61.3.743-747.1987","doi":"https://doi.org/10.1128/jvi.61.3.743-747.1987","is_oa":false,"landing_page_url":"https://doi.org/10.1128/jvi.61.3.743-747.1987","pdf_url":null,"source":{"id":"https://openalex.org/S96615428","display_name":"Journal of Virology","issn_l":"0022-538X","issn":["0022-538X","1070-6321","1098-5514"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-a","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320263","host_organization_name":"American Society for Microbiology","host_organization_lineage":["https://openalex.org/P4310320263"],"host_organization_lineage_names":["American Society for Microbiology"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Virology","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/254015","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5060177702","display_name":"David Derse","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"D Derse","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5066394708","display_name":"Patricia L. Dorn","orcid":"https://orcid.org/0000-0001-8555-7008","observed_orcids":["https://orcid.org/0000-0001-8555-7008"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"P L Dorn","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":null,"display_name":"L Levy","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"L Levy","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103702157","display_name":"Robert M. Stephens","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"R M Stephens","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109115849","display_name":"Nancy R. Rice","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"N R Rice","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5110186877","display_name":"J W Casey","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"J W Casey","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":1.7763,"has_fulltext":false,"cited_by_count":59,"citation_normalized_percentile":{"value":0.85129068,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":94},"biblio":{"volume":"61","issue":"3","first_page":"743","last_page":"747"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10112","display_name":"HIV Research and Treatment","score":0.850600004196167,"subfield":{"id":"https://openalex.org/subfields/2406","display_name":"Virology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10112","display_name":"HIV Research and Treatment","score":0.850600004196167,"subfield":{"id":"https://openalex.org/subfields/2406","display_name":"Virology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12159","display_name":"T-cell and Retrovirus Studies","score":0.13259999454021454,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10222","display_name":"Genomics and Chromatin Dynamics","score":0.002899999963119626,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/equine-infectious-anemia-virus","display_name":"equine infectious anemia virus","score":1.0},{"id":"https://openalex.org/keywords/long-terminal-repeat","display_name":"long terminal repeat","score":0.9229999780654907},{"id":"https://openalex.org/keywords/transcriptional-promoter","display_name":"transcriptional promoter","score":0.7250000238418579},{"id":"https://openalex.org/keywords/ccaat-box","display_name":"CCAAT box","score":0.7879999876022339},{"id":"https://openalex.org/keywords/transcriptional-activation","display_name":"transcriptional activation","score":0.7639999985694885},{"id":"https://openalex.org/keywords/proviral-clones","display_name":"proviral clones","score":0.6769999861717224},{"id":"https://openalex.org/keywords/chloramphenicol-acetyltransferase-reporter","display_name":"chloramphenicol acetyltransferase reporter","score":0.9079999923706055},{"id":"https://openalex.org/keywords/retroviral-transcription","display_name":"retroviral transcription","score":0.5239999890327454}],"concepts":[{"id":"https://openalex.org/C2781053568","wikidata":"https://www.wikidata.org/wiki/Q19000458","display_name":"Equine infectious anemia","level":3,"score":0.9738094806671143},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.8959740400314331},{"id":"https://openalex.org/C2780730277","wikidata":"https://www.wikidata.org/wiki/Q24744759","display_name":"Chloramphenicol acetyltransferase","level":5,"score":0.8864879608154297},{"id":"https://openalex.org/C199491388","wikidata":"https://www.wikidata.org/wiki/Q1869477","display_name":"Long terminal repeat","level":4,"score":0.8286045789718628},{"id":"https://openalex.org/C102906071","wikidata":"https://www.wikidata.org/wiki/Q422467","display_name":"Provirus","level":4,"score":0.7239018678665161},{"id":"https://openalex.org/C159047783","wikidata":"https://www.wikidata.org/wiki/Q7215","display_name":"Virology","level":1,"score":0.5703411102294922},{"id":"https://openalex.org/C2522874641","wikidata":"https://www.wikidata.org/wiki/Q808","display_name":"Virus","level":2,"score":0.531803548336029},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.510585367679596},{"id":"https://openalex.org/C2779690655","wikidata":"https://www.wikidata.org/wiki/Q374232","display_name":"Lentivirus","level":4,"score":0.48226815462112427},{"id":"https://openalex.org/C179926584","wikidata":"https://www.wikidata.org/wiki/Q207714","display_name":"Transcription (linguistics)","level":2,"score":0.4791752099990845},{"id":"https://openalex.org/C153911025","wikidata":"https://www.wikidata.org/wiki/Q7202","display_name":"Molecular biology","level":1,"score":0.4002211093902588},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.38937532901763916},{"id":"https://openalex.org/C101762097","wikidata":"https://www.wikidata.org/wiki/Q224093","display_name":"Promoter","level":4,"score":0.36782628297805786},{"id":"https://openalex.org/C150194340","wikidata":"https://www.wikidata.org/wiki/Q26972","display_name":"Gene expression","level":3,"score":0.3294241726398468},{"id":"https://openalex.org/C141231307","wikidata":"https://www.wikidata.org/wiki/Q7020","display_name":"Genome","level":3,"score":0.10024625062942505},{"id":"https://openalex.org/C2780727368","wikidata":"https://www.wikidata.org/wiki/Q1928978","display_name":"Viral disease","level":3,"score":0.07686042785644531},{"id":"https://openalex.org/C41895202","wikidata":"https://www.wikidata.org/wiki/Q8162","display_name":"Linguistics","level":1,"score":0.0},{"id":"https://openalex.org/C138885662","wikidata":"https://www.wikidata.org/wiki/Q5891","display_name":"Philosophy","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D001483","descriptor_name":"Base Sequence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004860","descriptor_name":"Infectious Anemia Virus, Equine","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D005786","descriptor_name":"Gene Expression Regulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011401","descriptor_name":"Promoter Regions, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012091","descriptor_name":"Repetitive Sequences, Nucleic Acid","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012333","descriptor_name":"RNA, Messenger","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D013045","descriptor_name":"Species Specificity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014158","descriptor_name":"Transcription, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1128/jvi.61.3.743-747.1987","doi":"https://doi.org/10.1128/jvi.61.3.743-747.1987","is_oa":false,"landing_page_url":"https://doi.org/10.1128/jvi.61.3.743-747.1987","pdf_url":null,"source":{"id":"https://openalex.org/S96615428","display_name":"Journal of Virology","issn_l":"0022-538X","issn":["0022-538X","1070-6321","1098-5514"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-a","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320263","host_organization_name":"American Society for Microbiology","host_organization_lineage":["https://openalex.org/P4310320263"],"host_organization_lineage_names":["American Society for Microbiology"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Virology","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:254015","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/254015","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"J Virol","raw_type":"Text"},{"id":"pmid:3027401","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/3027401","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of virology","raw_type":"Journal Article"}],"best_oa_location":{"id":"pmh:oai:pubmedcentral.nih.gov:254015","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/254015","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"J Virol","raw_type":"Text"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.4000000059604645}],"study_designs":[],"awards":[{"id":"https://openalex.org/G1046201344","display_name":"OPERATIONS AT THE NCI FREDERICK FACILITY","funder_award_id":"n01co023910-029","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G195261642","display_name":null,"funder_award_id":"N0-1-CO-23910","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"}],"funders":[{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337351","display_name":"National Cancer Institute","ror":"https://ror.org/040gcmg81"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":32,"referenced_works":["https://openalex.org/W1558516755","https://openalex.org/W1588024596","https://openalex.org/W1965324884","https://openalex.org/W1965372133","https://openalex.org/W1967425449","https://openalex.org/W1974532571","https://openalex.org/W1981014117","https://openalex.org/W1981585109","https://openalex.org/W1998439550","https://openalex.org/W1998461588","https://openalex.org/W1999053228","https://openalex.org/W1999059818","https://openalex.org/W2010356985","https://openalex.org/W2011603889","https://openalex.org/W2012704007","https://openalex.org/W2013357966","https://openalex.org/W2016655706","https://openalex.org/W2016780880","https://openalex.org/W2022627708","https://openalex.org/W2028706937","https://openalex.org/W2038335028","https://openalex.org/W2046462022","https://openalex.org/W2055720718","https://openalex.org/W2060880451","https://openalex.org/W2065716796","https://openalex.org/W2069948707","https://openalex.org/W2080553531","https://openalex.org/W2084678798","https://openalex.org/W2084938604","https://openalex.org/W2144206181","https://openalex.org/W2144634347","https://openalex.org/W2292552118"],"related_works":["https://openalex.org/W1895088320","https://openalex.org/W1529089011","https://openalex.org/W2358642398","https://openalex.org/W1852584301","https://openalex.org/W2756685490","https://openalex.org/W2065139987","https://openalex.org/W2017562082","https://openalex.org/W1975185922","https://openalex.org/W2377301684","https://openalex.org/W2032810199"],"abstract_inverted_index":{"The":[0,102],"long":[1],"terminal":[2],"repeats":[3],"(LTRs)":[4],"of":[5,30,48,54,63,97,104,148],"equine":[6],"infectious":[7],"anemia":[8],"virus":[9],"(EIAV)":[10],"were":[11,113],"examined":[12],"with":[13,124],"respect":[14],"to":[15,18,82,132,141,145],"their":[16,125],"ability":[17],"function":[19],"as":[20],"transcriptional":[21],"promoters":[22],"in":[23,58,69,120],"various":[24,91],"cellular":[25],"environments.":[26],"Nucleotide":[27],"sequence":[28,57],"analyses":[29],"the":[31,40,49,59,64,70,83,110],"LTRs":[32,112],"derived":[33],"from":[34],"two":[35],"unique":[36],"proviral":[37],"clones":[38],"revealed":[39],"requisite":[41],"consensus":[42],"transcription":[43],"and":[44,88,99,116],"processing":[45],"signals.":[46],"One":[47],"proviruses":[50],"possessed":[51],"a":[52,55,136],"duplication":[53],"16-base-pair":[56],"CCAAT":[60],"box":[61],"region":[62],"LTR":[65,79],"which":[66],"was":[67,80],"absent":[68],"other":[71,150],"provirus.":[72],"To":[73],"assess":[74],"its":[75],"functional":[76],"activity,":[77],"each":[78],"coupled":[81],"bacterial":[84],"chloramphenicol":[85,105],"acetyltransferase":[86,106],"gene":[87],"transfected":[89],"onto":[90],"cell":[92],"lines,":[93],"including":[94],"matched":[95],"cultures":[96],"EIAV-infected":[98,121],"uninfected":[100,126],"cells.":[101],"levels":[103],"activity":[107],"directed":[108],"by":[109,135],"EIAV":[111,129],"between":[114],"250":[115],"900":[117],"times":[118],"greater":[119],"cells":[122],"compared":[123],"counterparts.":[127],"Thus,":[128],"expression":[130,147],"appears":[131],"be":[133],"activated":[134],"virus-induced":[137],"trans-activation":[138],"phenomenon":[139],"analogous":[140],"that":[142],"recently":[143],"shown":[144],"amplify":[146],"certain":[149],"lentiviruses.":[151]},"counts_by_year":[{"year":2016,"cited_by_count":1},{"year":2015,"cited_by_count":1},{"year":2014,"cited_by_count":1},{"year":2012,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}