{"id":"https://openalex.org/W2132381902","doi":"https://doi.org/10.1073/pnas.95.26.15741","title":"Fluctuations and stimulus-induced changes in blood flow observed in individual capillaries in layers 2 through 4 of rat neocortex","display_name":"Fluctuations and stimulus-induced changes in blood flow observed in individual capillaries in layers 2 through 4 of rat neocortex","publication_year":1998,"publication_date":"1998-12-22","ids":{"openalex":"https://openalex.org/W2132381902","doi":"https://doi.org/10.1073/pnas.95.26.15741","mag":"2132381902","pmid":"https://pubmed.ncbi.nlm.nih.gov/9861040","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/28114"},"language":"en","primary_location":{"id":"doi:10.1073/pnas.95.26.15741","doi":"https://doi.org/10.1073/pnas.95.26.15741","is_oa":false,"landing_page_url":"https://doi.org/10.1073/pnas.95.26.15741","pdf_url":null,"source":{"id":"https://openalex.org/S125754415","display_name":"Proceedings of the National Academy of Sciences","issn_l":"0027-8424","issn":["0027-8424","1091-6490"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-a","doyens","erih-plus","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320052","host_organization_name":"National Academy of Sciences","host_organization_lineage":["https://openalex.org/P4310320052"],"host_organization_lineage_names":["National Academy of Sciences"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Proceedings of the National Academy of Sciences","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"http://europepmc.org/pmc/articles/PMC28114","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5020283755","display_name":"David Kleinfeld","orcid":"https://orcid.org/0000-0001-9797-4722","observed_orcids":["https://orcid.org/0000-0001-9797-4722"]},"institutions":[{"id":"https://openalex.org/I36258959","display_name":"University of California San Diego","ror":"https://ror.org/0168r3w48","country_code":"US","type":"education","lineage":["https://openalex.org/I36258959"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"David Kleinfeld","raw_affiliation_strings":["Department of Physics, University of California at San Diego, 9500 Gilman Drive, La Jolla, CA 92093-0319; and Bell Laboratories, Lucent Technologies, 700 Mountain Avenue, Murray Hill, NJ 07974"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Physics, University of California at San Diego, 9500 Gilman Drive, La Jolla, CA 92093-0319; and Bell Laboratories, Lucent Technologies, 700 Mountain Avenue, Murray Hill, NJ 07974","institution_ids":["https://openalex.org/I36258959"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5037732748","display_name":"Partha P. Mitra","orcid":"https://orcid.org/0000-0001-8818-6804","observed_orcids":["https://orcid.org/0000-0001-8818-6804"]},"institutions":[{"id":"https://openalex.org/I36258959","display_name":"University of California San Diego","ror":"https://ror.org/0168r3w48","country_code":"US","type":"education","lineage":["https://openalex.org/I36258959"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Partha P. Mitra","raw_affiliation_strings":["Department of Physics, University of California at San Diego, 9500 Gilman Drive, La Jolla, CA 92093-0319; and Bell Laboratories, Lucent Technologies, 700 Mountain Avenue, Murray Hill, NJ 07974"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Physics, University of California at San Diego, 9500 Gilman Drive, La Jolla, CA 92093-0319; and Bell Laboratories, Lucent Technologies, 700 Mountain Avenue, Murray Hill, NJ 07974","institution_ids":["https://openalex.org/I36258959"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5038528403","display_name":"Fritjof Helmchen","orcid":"https://orcid.org/0000-0002-8867-9569","observed_orcids":["https://orcid.org/0000-0002-8867-9569"]},"institutions":[{"id":"https://openalex.org/I36258959","display_name":"University of California San Diego","ror":"https://ror.org/0168r3w48","country_code":"US","type":"education","lineage":["https://openalex.org/I36258959"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Fritjof Helmchen","raw_affiliation_strings":["Department of Physics, University of California at San Diego, 9500 Gilman Drive, La Jolla, CA 92093-0319; and Bell Laboratories, Lucent Technologies, 700 Mountain Avenue, Murray Hill, NJ 07974"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Physics, University of California at San Diego, 9500 Gilman Drive, La Jolla, CA 92093-0319; and Bell Laboratories, Lucent Technologies, 700 Mountain Avenue, Murray Hill, NJ 07974","institution_ids":["https://openalex.org/I36258959"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5020934124","display_name":"Winfried T. Denk","orcid":"https://orcid.org/0000-0002-0704-6998","observed_orcids":["https://orcid.org/0000-0002-0704-6998"]},"institutions":[{"id":"https://openalex.org/I36258959","display_name":"University of California San Diego","ror":"https://ror.org/0168r3w48","country_code":"US","type":"education","lineage":["https://openalex.org/I36258959"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Winfried Denk","raw_affiliation_strings":["Department of Physics, University of California at San Diego, 9500 Gilman Drive, La Jolla, CA 92093-0319; and Bell Laboratories, Lucent Technologies, 700 Mountain Avenue, Murray Hill, NJ 07974"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Physics, University of California at San Diego, 9500 Gilman Drive, La Jolla, CA 92093-0319; and Bell Laboratories, Lucent Technologies, 700 Mountain Avenue, Murray Hill, NJ 07974","institution_ids":["https://openalex.org/I36258959"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I36258959"],"apc_list":null,"apc_paid":null,"fwci":4.9469,"has_fulltext":false,"cited_by_count":832,"citation_normalized_percentile":{"value":0.9580574,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":99,"max":100},"biblio":{"volume":"95","issue":"26","first_page":"15741","last_page":"15746"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11872","display_name":"Barrier Structure and Function Studies","score":0.3978999853134155,"subfield":{"id":"https://openalex.org/subfields/2808","display_name":"Neurology"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11872","display_name":"Barrier Structure and Function Studies","score":0.3978999853134155,"subfield":{"id":"https://openalex.org/subfields/2808","display_name":"Neurology"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11721","display_name":"Blood properties and coagulation","score":0.2888000011444092,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10706","display_name":"Traumatic Brain Injury and Neurovascular Disturbances","score":0.10279999673366547,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/capillary-blood-flow","display_name":"capillary blood flow","score":0.8500000238418579},{"id":"https://openalex.org/keywords/red-blood-cell-dynamics","display_name":"red blood cell dynamics","score":0.6290000081062317},{"id":"https://openalex.org/keywords/cortical-microcirculation","display_name":"cortical microcirculation","score":0.6209999918937683},{"id":"https://openalex.org/keywords/neocortex","display_name":"neocortex","score":0.7440000176429749},{"id":"https://openalex.org/keywords/primary-somatosensory-cortex","display_name":"primary somatosensory cortex","score":0.890999972820282},{"id":"https://openalex.org/keywords/capillary-resistance","display_name":"capillary resistance","score":0.699999988079071},{"id":"https://openalex.org/keywords/red-blood-cell-velocity","display_name":"red blood cell velocity","score":0.6169999837875366},{"id":"https://openalex.org/keywords/red-blood-cell-density","display_name":"red blood cell density","score":0.9200000166893005}],"concepts":[{"id":"https://openalex.org/C172497186","wikidata":"https://www.wikidata.org/wiki/Q328835","display_name":"Somatosensory system","level":2,"score":0.7347251176834106},{"id":"https://openalex.org/C2777222312","wikidata":"https://www.wikidata.org/wiki/Q726562","display_name":"Neocortex","level":2,"score":0.5896859169006348},{"id":"https://openalex.org/C24998067","wikidata":"https://www.wikidata.org/wiki/Q4114622","display_name":"Stimulation","level":2,"score":0.5593904256820679},{"id":"https://openalex.org/C2779918689","wikidata":"https://www.wikidata.org/wiki/Q3771842","display_name":"Stimulus (psychology)","level":2,"score":0.5441842675209045},{"id":"https://openalex.org/C12554922","wikidata":"https://www.wikidata.org/wiki/Q7100","display_name":"Biophysics","level":1,"score":0.5195577144622803},{"id":"https://openalex.org/C158846371","wikidata":"https://www.wikidata.org/wiki/Q1642137","display_name":"Blood flow","level":2,"score":0.5068152546882629},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.4643018841743469},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.460757315158844},{"id":"https://openalex.org/C105702510","wikidata":"https://www.wikidata.org/wiki/Q514","display_name":"Anatomy","level":1,"score":0.42075905203819275},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.34981054067611694},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.15896502137184143},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.09773164987564087},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.08666443824768066},{"id":"https://openalex.org/C542102704","wikidata":"https://www.wikidata.org/wiki/Q183257","display_name":"Psychotherapist","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001783","descriptor_name":"Blood Flow Velocity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D001931","descriptor_name":"Brain Mapping","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D002196","descriptor_name":"Capillaries","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D002560","descriptor_name":"Cerebrovascular Circulation","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D004912","descriptor_name":"Erythrocytes","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009474","descriptor_name":"Neurons","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D012039","descriptor_name":"Regional Blood Flow","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014738","descriptor_name":"Vibrissae","qualifier_ui":"Q000294","qualifier_name":"innervation","is_major_topic":false},{"descriptor_ui":"D017207","descriptor_name":"Rats, Sprague-Dawley","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019579","descriptor_name":"Neocortex","qualifier_ui":"Q000098","qualifier_name":"blood supply","is_major_topic":true},{"descriptor_ui":"D019579","descriptor_name":"Neocortex","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D051381","descriptor_name":"Rats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":10,"locations":[{"id":"doi:10.1073/pnas.95.26.15741","doi":"https://doi.org/10.1073/pnas.95.26.15741","is_oa":false,"landing_page_url":"https://doi.org/10.1073/pnas.95.26.15741","pdf_url":null,"source":{"id":"https://openalex.org/S125754415","display_name":"Proceedings of the National Academy of Sciences","issn_l":"0027-8424","issn":["0027-8424","1091-6490"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-a","doyens","erih-plus","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320052","host_organization_name":"National Academy of Sciences","host_organization_lineage":["https://openalex.org/P4310320052"],"host_organization_lineage_names":["National Academy of Sciences"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Proceedings of the National Academy of Sciences","raw_type":"journal-article"},{"id":"pmh:oai:europepmc.org:191941","doi":null,"is_oa":true,"landing_page_url":"http://europepmc.org/pmc/articles/PMC28114","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"","raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:28114","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/28114","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Proc Natl Acad Sci U S A","raw_type":"Text"},{"id":"pmid:9861040","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/9861040","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Proceedings of the National Academy of Sciences of the United States of America","raw_type":"Journal Article"},{"id":"pmh:oai:repository.cshl.edu:25841","doi":null,"is_oa":false,"landing_page_url":"https://repository.cshl.edu/id/eprint/25841/1/Mitra_PNAS_1998.pdf","pdf_url":"https://repository.cshl.edu/id/eprint/25841/1/Mitra_PNAS_1998.pdf","source":{"id":"https://openalex.org/S4306402288","display_name":"Cold Spring Harbor Laboratory Institutional Repository (Cold Spring Harbor Laboratory)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I2750212522","host_organization_name":"Cold Spring Harbor Laboratory","host_organization_lineage":["https://openalex.org/I2750212522"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":null,"raw_type":"Paper"},{"id":"pmh:oai:edoc.mpg.de:22585","doi":null,"is_oa":false,"landing_page_url":"http://edoc.mpg.de/22585","pdf_url":null,"source":{"id":"https://openalex.org/S4406922265","display_name":"Max Planck Institute for Plasma Physics","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"PNAS Online 1990 - Present, v.95, 15741-15746 (1998)","raw_type":"Article"},{"id":"pmh:oai:edoc.mpg.de:23218","doi":null,"is_oa":false,"landing_page_url":"http://edoc.mpg.de/23218","pdf_url":null,"source":{"id":"https://openalex.org/S4406922265","display_name":"Max Planck Institute for Plasma Physics","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"PNAS Online 1990 - Present, v.95, 15741-15746 (1998)","raw_type":"Article"},{"id":"pmh:oai:escidoc.org:escidoc:2339449","doi":null,"is_oa":false,"landing_page_url":"http://hdl.handle.net/11858/00-001M-0000-002B-366D-0","pdf_url":null,"source":{"id":"https://openalex.org/S7407052962","display_name":"Max Planck Digital Library","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4210088280","host_organization_name":"Max Planck Digital Library","host_organization_lineage":["https://openalex.org/I4210088280"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:pure.mpg.de:item_2170916","doi":null,"is_oa":false,"landing_page_url":"http://hdl.handle.net/11858/00-001M-0000-0019-A413-F","pdf_url":null,"source":{"id":"https://openalex.org/S4306400654","display_name":"MPG.PuRe (Max Planck Society)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I149899117","host_organization_name":"Max Planck Society","host_organization_lineage":["https://openalex.org/I149899117"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Proceedings of the National Academy of Sciences of the United States of America","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:pure.mpg.de:item_2339449","doi":null,"is_oa":false,"landing_page_url":"http://hdl.handle.net/11858/00-001M-0000-002B-366D-0","pdf_url":null,"source":{"id":"https://openalex.org/S4306400654","display_name":"MPG.PuRe (Max Planck Society)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I149899117","host_organization_name":"Max Planck Society","host_organization_lineage":["https://openalex.org/I149899117"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Proceedings of the National Academy of Sciences of the United States of America","raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":{"id":"pmh:oai:europepmc.org:191941","doi":null,"is_oa":true,"landing_page_url":"http://europepmc.org/pmc/articles/PMC28114","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"","raw_type":"Text"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.4043000042438507}],"sustainable_development_goals_aurora":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":37,"referenced_works":["https://openalex.org/W641242542","https://openalex.org/W1530987197","https://openalex.org/W1554532831","https://openalex.org/W1601798363","https://openalex.org/W1886784899","https://openalex.org/W1906348537","https://openalex.org/W1970649851","https://openalex.org/W1972681874","https://openalex.org/W1984764602","https://openalex.org/W1994971749","https://openalex.org/W1996676294","https://openalex.org/W2000664542","https://openalex.org/W2004633434","https://openalex.org/W2009106604","https://openalex.org/W2014960948","https://openalex.org/W2027128479","https://openalex.org/W2031373494","https://openalex.org/W2038035800","https://openalex.org/W2043298666","https://openalex.org/W2053788715","https://openalex.org/W2054797412","https://openalex.org/W2054941493","https://openalex.org/W2056109168","https://openalex.org/W2061464631","https://openalex.org/W2067836141","https://openalex.org/W2072972754","https://openalex.org/W2082065600","https://openalex.org/W2085467935","https://openalex.org/W2110935910","https://openalex.org/W2119227505","https://openalex.org/W2150617546","https://openalex.org/W2155722796","https://openalex.org/W2157312458","https://openalex.org/W2213436489","https://openalex.org/W4241190342","https://openalex.org/W4251786266","https://openalex.org/W6600095121"],"related_works":["https://openalex.org/W1985694790","https://openalex.org/W2144168780","https://openalex.org/W2791599622","https://openalex.org/W2376860413","https://openalex.org/W2098090577","https://openalex.org/W2016954114","https://openalex.org/W2077202942","https://openalex.org/W2049092760","https://openalex.org/W2902409742","https://openalex.org/W2254454494"],"abstract_inverted_index":{"Cortical":[0],"blood":[1,36,53],"flow":[2,16,37,94,230],"at":[3,38,129,153,169,175],"the":[4,10,25,28,33,49,67,79,83,93,117,149,160,184,202,213,223,226,239,242,251],"level":[5],"of":[6,12,22,35,51,70,86,113,125,132,138,156,165,172,188,197,217,225,244,254],"individual":[7,57],"capillaries":[8,18,58],"and":[9,27,88,98,110,119,163,215,241],"coupling":[11],"neuronal":[13],"activity":[14],"to":[15,47,151,183,195,208,269],"in":[17,24,56,74,180,193,212,219,229,266],"are":[19,167,260],"fundamental":[20],"aspects":[21],"homeostasis":[23],"normal":[26],"diseased":[29],"brain.":[30],"To":[31],"probe":[32],"dynamics":[34],"this":[39,76],"level,":[40],"we":[41,205],"used":[42],"two-photon":[43],"laser":[44],"scanning":[45],"microscopy":[46],"image":[48],"motion":[50],"red":[52],"cells":[54,141],"(RBCs)":[55],"that":[59,92],"lie":[60],"as":[61,63,105,107],"far":[62],"600":[64],"micrometers":[65],"below":[66],"pia":[68],"mater":[69],"primary":[71],"somatosensory":[72,189],"cortex":[73],"rat;":[75],"depth":[77],"encompassed":[78],"cortical":[80],"layers":[81],"with":[82,134,262],"highest":[84],"density":[85,137,164,253],"neurons":[87],"capillaries.":[89],"We":[90],"observed":[91,192],"was":[95],"quite":[96],"variable":[97],"exhibited":[99],"temporal":[100],"fluctuations":[101],"around":[102],"0.1":[103],"Hz,":[104],"well":[106],"prolonged":[108],"stalls":[109],"occasional":[111],"reversals":[112],"direction.":[114],"On":[115,237],"average,":[116,238],"speed":[118,150,216,243],"flux":[120,173,214,240],"(cells":[121],"per":[122,142],"unit":[123],"time)":[124],"RBCs":[126,166,218,245,255],"covaried":[127],"linearly":[128],"low":[130,176],"values":[131,155,171],"flux,":[133],"a":[135,146,263],"linear":[136,252],"approximately":[139],"70":[140],"mm,":[143],"followed":[144],"by":[145,234],"tendency":[147],"for":[148],"plateau":[152],"high":[154,170],"flux.":[157],"Thus,":[158],"both":[159],"average":[161],"velocity":[162],"greater":[168],"than":[174],"values.":[177],"Time-locked":[178],"changes":[179,211,228],"flow,":[181],"localized":[182],"appropriate":[185],"anatomical":[186],"region":[187],"cortex,":[190],"were":[191,206,231],"response":[194],"stimulation":[196],"either":[198],"multiple":[199],"vibrissae":[200],"or":[201],"hindlimb.":[203],"Although":[204],"able":[207],"detect":[209],"stimulus-induced":[210,264],"some":[220],"single":[221],"trials,":[222],"amplitude":[224],"stimulus-evoked":[227],"largely":[232],"masked":[233],"basal":[235],"fluctuations.":[236],"increased":[246],"transiently":[247],"on":[248],"stimulation,":[249],"although":[250],"decreased":[256],"slightly.":[257],"These":[258],"findings":[259],"consistent":[261],"decrease":[265],"capillary":[267],"resistance":[268],"flow.":[270]},"counts_by_year":[{"year":2026,"cited_by_count":18},{"year":2025,"cited_by_count":25},{"year":2024,"cited_by_count":29},{"year":2023,"cited_by_count":20},{"year":2022,"cited_by_count":33},{"year":2021,"cited_by_count":29},{"year":2020,"cited_by_count":23},{"year":2019,"cited_by_count":38},{"year":2018,"cited_by_count":40},{"year":2017,"cited_by_count":32},{"year":2016,"cited_by_count":30},{"year":2015,"cited_by_count":43},{"year":2014,"cited_by_count":42},{"year":2013,"cited_by_count":42},{"year":2012,"cited_by_count":51}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}