{"id":"https://openalex.org/W2132373390","doi":"https://doi.org/10.1016/s0015-0282(01)01829-5","title":"Effects of lower doses of conjugated equine estrogens and medroxyprogesterone acetate on plasma lipids and lipoproteins, coagulation factors, and carbohydrate metabolism","display_name":"Effects of lower doses of conjugated equine estrogens and medroxyprogesterone acetate on plasma lipids and lipoproteins, coagulation factors, and carbohydrate metabolism","publication_year":2001,"publication_date":"2001-07-01","ids":{"openalex":"https://openalex.org/W2132373390","doi":"https://doi.org/10.1016/s0015-0282(01)01829-5","mag":"2132373390","pmid":"https://pubmed.ncbi.nlm.nih.gov/11438314"},"language":"en","primary_location":{"id":"doi:10.1016/s0015-0282(01)01829-5","doi":"https://doi.org/10.1016/s0015-0282(01)01829-5","is_oa":true,"landing_page_url":"https://doi.org/10.1016/s0015-0282(01)01829-5","pdf_url":"http://www.fertstert.org/article/S0015028201018295/pdf","source":{"id":"https://openalex.org/S45445671","display_name":"Fertility and Sterility","issn_l":"0015-0282","issn":["0015-0282","1556-5653"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Fertility and Sterility","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"http://www.fertstert.org/article/S0015028201018295/pdf","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5007554920","display_name":"Rogerio A. L\u00f8bo","orcid":"https://orcid.org/0000-0002-1472-8313","observed_orcids":["https://orcid.org/0000-0002-1472-8313"]},"institutions":[{"id":"https://openalex.org/I2799503643","display_name":"Columbia University Irving Medical Center","ror":"https://ror.org/01esghr10","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2799503643"]},{"id":"https://openalex.org/I78577930","display_name":"Columbia University","ror":"https://ror.org/00hj8s172","country_code":"US","type":"education","lineage":["https://openalex.org/I78577930"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Rogerio A Lobo","raw_affiliation_strings":["Department of Obstetrics and Gynecology, Columbia-Presbyterian Medical Center, New York, New York 10032-3784, USA. ral35@columbia.edu","Department of Obstetrics and Gynecology, Columbia-Presbyterian Medical Center New York, New York, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Obstetrics and Gynecology, Columbia-Presbyterian Medical Center, New York, New York 10032-3784, USA. ral35@columbia.edu","institution_ids":["https://openalex.org/I2799503643","https://openalex.org/I78577930"]},{"raw_affiliation_string":"Department of Obstetrics and Gynecology, Columbia-Presbyterian Medical Center New York, New York, USA","institution_ids":["https://openalex.org/I2799503643"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110382988","display_name":"Trudy L. Bush","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I126744593","display_name":"University of Maryland, Baltimore","ror":"https://ror.org/04rq5mt64","country_code":"US","type":"education","lineage":["https://openalex.org/I126744593"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Trudy Bush","raw_affiliation_strings":["Department of Epidemiology and Preventive Medicine, University of Maryland School of Medicine, Baltimore, Maryland, USA","Department of Epidemiology & Preventive Medicine, University of Maryland School of Medicine, Baltimore, Maryland, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Epidemiology and Preventive Medicine, University of Maryland School of Medicine, Baltimore, Maryland, USA","institution_ids":["https://openalex.org/I126744593"]},{"raw_affiliation_string":"Department of Epidemiology & Preventive Medicine, University of Maryland School of Medicine, Baltimore, Maryland, USA","institution_ids":["https://openalex.org/I126744593"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103407886","display_name":"Bruce Richard Carr","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I867280407","display_name":"The University of Texas Southwestern Medical Center","ror":"https://ror.org/05byvp690","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I867280407"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Bruce R Carr","raw_affiliation_strings":["Department of Obstetrics and Gynecology, University of Texas Southwestern Medical Center, Dallas, Texas, USA","Department of Obstetrics & Gynecology, University of Texas Southwestern Medical Center, Dallas, Texas USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Obstetrics and Gynecology, University of Texas Southwestern Medical Center, Dallas, Texas, USA","institution_ids":["https://openalex.org/I867280407"]},{"raw_affiliation_string":"Department of Obstetrics & Gynecology, University of Texas Southwestern Medical Center, Dallas, Texas USA","institution_ids":["https://openalex.org/I867280407"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5071092589","display_name":"James H. Pickar","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4403928396","display_name":"Wyeth","ror":"https://ror.org/035j24j42","country_code":"US","type":"company","lineage":["https://openalex.org/I180857899","https://openalex.org/I4403928396"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"James H Pickar","raw_affiliation_strings":["Clinical Research and Development, Wyeth-Ayerst Research, Philadelphia, Pennsylvania, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Clinical Research and Development, Wyeth-Ayerst Research, Philadelphia, Pennsylvania, USA","institution_ids":["https://openalex.org/I4403928396"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":5,"corresponding_author_ids":["https://openalex.org/A5007554920"],"corresponding_institution_ids":["https://openalex.org/I2799503643","https://openalex.org/I78577930"],"apc_list":{"value":4220,"currency":"USD","value_usd":4220},"apc_paid":null,"fwci":15.0989,"has_fulltext":false,"cited_by_count":199,"citation_normalized_percentile":{"value":0.99384319,"is_in_top_1_percent":true,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":89,"max":99},"biblio":{"volume":"76","issue":"1","first_page":"13","last_page":"24"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10694","display_name":"Menopause: Health Impacts and Treatments","score":0.9976000189781189,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10694","display_name":"Menopause: Health Impacts and Treatments","score":0.9976000189781189,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10394","display_name":"Lipoproteins and Cardiovascular Health","score":0.0010000000474974513,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10756","display_name":"Estrogen and related hormone effects","score":0.0007999999797903001,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/conjugated-equine-estrogens","display_name":"conjugated equine estrogens","score":0.9959999918937683},{"id":"https://openalex.org/keywords/medroxyprogesterone-acetate","display_name":"medroxyprogesterone acetate","score":1.0},{"id":"https://openalex.org/keywords/low-dose-hormone-replacement-therapy","display_name":"low-dose hormone replacement therapy","score":0.7490000128746033},{"id":"https://openalex.org/keywords/postmenopausal-women","display_name":"postmenopausal women","score":0.9850000143051147},{"id":"https://openalex.org/keywords/plasma-lipids","display_name":"plasma lipids","score":0.8920000195503235},{"id":"https://openalex.org/keywords/lipoproteins","display_name":"lipoproteins","score":0.9319999814033508},{"id":"https://openalex.org/keywords/hdl-cholesterol","display_name":"HDL cholesterol","score":0.9020000100135803},{"id":"https://openalex.org/keywords/ldl-cholesterol","display_name":"LDL cholesterol","score":0.8730000257492065},{"id":"https://openalex.org/keywords/apolipoprotein-a-i","display_name":"apolipoprotein A-I","score":0.9380000233650208},{"id":"https://openalex.org/keywords/apolipoprotein-b","display_name":"apolipoprotein B","score":0.9559999704360962},{"id":"https://openalex.org/keywords/lipoprotein-a","display_name":"lipoprotein(a)","score":0.9679999947547913},{"id":"https://openalex.org/keywords/carbohydrate-metabolism","display_name":"carbohydrate metabolism","score":0.6200000047683716},{"id":"https://openalex.org/keywords/glucose-tolerance","display_name":"glucose tolerance","score":0.9739999771118164},{"id":"https://openalex.org/keywords/coagulation-factors","display_name":"coagulation factors","score":0.8980000019073486},{"id":"https://openalex.org/keywords/fibrinolysis","display_name":"fibrinolysis","score":0.859000027179718}],"concepts":[{"id":"https://openalex.org/C2776306185","wikidata":"https://www.wikidata.org/wiki/Q2823834","display_name":"Medroxyprogesterone acetate","level":3,"score":0.7340042591094971},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.7097683548927307},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.6538883447647095},{"id":"https://openalex.org/C2775934596","wikidata":"https://www.wikidata.org/wiki/Q416667","display_name":"Medroxyprogesterone","level":4,"score":0.5781979560852051},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.5595479011535645},{"id":"https://openalex.org/C62746215","wikidata":"https://www.wikidata.org/wiki/Q14890615","display_name":"Apolipoprotein B","level":3,"score":0.5545583367347717},{"id":"https://openalex.org/C2779036427","wikidata":"https://www.wikidata.org/wiki/Q381899","display_name":"Fibrinogen","level":2,"score":0.5024337768554688},{"id":"https://openalex.org/C2778913445","wikidata":"https://www.wikidata.org/wiki/Q186319","display_name":"Triglyceride","level":3,"score":0.5013861656188965},{"id":"https://openalex.org/C2780072125","wikidata":"https://www.wikidata.org/wiki/Q28350","display_name":"Lipoprotein","level":3,"score":0.4906558096408844},{"id":"https://openalex.org/C2778163477","wikidata":"https://www.wikidata.org/wiki/Q43656","display_name":"Cholesterol","level":2,"score":0.45736604928970337},{"id":"https://openalex.org/C2780541478","wikidata":"https://www.wikidata.org/wiki/Q410020","display_name":"High-density lipoprotein","level":3,"score":0.41600728034973145},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.29765254259109497},{"id":"https://openalex.org/C2777164284","wikidata":"https://www.wikidata.org/wiki/Q277954","display_name":"Estrogen","level":2,"score":0.2768881320953369}],"mesh":[{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001779","descriptor_name":"Blood Coagulation Factors","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":true},{"descriptor_ui":"D004305","descriptor_name":"Dose-Response Relationship, Drug","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004311","descriptor_name":"Double-Blind Method","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004359","descriptor_name":"Drug Therapy, Combination","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004966","descriptor_name":"Estrogens, Conjugated (USP)","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":true},{"descriptor_ui":"D004966","descriptor_name":"Estrogens, Conjugated (USP)","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006736","descriptor_name":"Horses","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008055","descriptor_name":"Lipids","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D008074","descriptor_name":"Lipoproteins","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015914","descriptor_name":"Estrogen Replacement Therapy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017258","descriptor_name":"Medroxyprogesterone Acetate","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":true},{"descriptor_ui":"D017258","descriptor_name":"Medroxyprogesterone Acetate","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D017698","descriptor_name":"Postmenopause","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D050260","descriptor_name":"Carbohydrate Metabolism","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1016/s0015-0282(01)01829-5","doi":"https://doi.org/10.1016/s0015-0282(01)01829-5","is_oa":true,"landing_page_url":"https://doi.org/10.1016/s0015-0282(01)01829-5","pdf_url":"http://www.fertstert.org/article/S0015028201018295/pdf","source":{"id":"https://openalex.org/S45445671","display_name":"Fertility and Sterility","issn_l":"0015-0282","issn":["0015-0282","1556-5653"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Fertility and Sterility","raw_type":"journal-article"},{"id":"pmid:11438314","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/11438314","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Fertility and sterility","raw_type":"Clinical Trial"}],"best_oa_location":{"id":"doi:10.1016/s0015-0282(01)01829-5","doi":"https://doi.org/10.1016/s0015-0282(01)01829-5","is_oa":true,"landing_page_url":"https://doi.org/10.1016/s0015-0282(01)01829-5","pdf_url":"http://www.fertstert.org/article/S0015028201018295/pdf","source":{"id":"https://openalex.org/S45445671","display_name":"Fertility and Sterility","issn_l":"0015-0282","issn":["0015-0282","1556-5653"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Fertility and Sterility","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.9922999739646912}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":56,"referenced_works":["https://openalex.org/W1491921704","https://openalex.org/W1532187436","https://openalex.org/W1823284780","https://openalex.org/W1860487341","https://openalex.org/W1964867773","https://openalex.org/W1972393754","https://openalex.org/W1978675042","https://openalex.org/W1984634515","https://openalex.org/W1986009920","https://openalex.org/W1988882351","https://openalex.org/W1993318146","https://openalex.org/W2000111910","https://openalex.org/W2000137056","https://openalex.org/W2006492282","https://openalex.org/W2008492445","https://openalex.org/W2018611651","https://openalex.org/W2028655493","https://openalex.org/W2031570803","https://openalex.org/W2033288663","https://openalex.org/W2049967476","https://openalex.org/W2050108803","https://openalex.org/W2050847671","https://openalex.org/W2059022881","https://openalex.org/W2059128672","https://openalex.org/W2071483128","https://openalex.org/W2081480597","https://openalex.org/W2082637848","https://openalex.org/W2108635758","https://openalex.org/W2111208312","https://openalex.org/W2112764454","https://openalex.org/W2113264115","https://openalex.org/W2114724335","https://openalex.org/W2126126879","https://openalex.org/W2130066230","https://openalex.org/W2143520738","https://openalex.org/W2144238512","https://openalex.org/W2144839356","https://openalex.org/W2155315816","https://openalex.org/W2159416358","https://openalex.org/W2249244861","https://openalex.org/W2323923429","https://openalex.org/W2325157096","https://openalex.org/W2328518988","https://openalex.org/W2332056249","https://openalex.org/W2333702587","https://openalex.org/W2335240422","https://openalex.org/W2416045675","https://openalex.org/W2417365582","https://openalex.org/W2419616247","https://openalex.org/W2521288629","https://openalex.org/W3140255517","https://openalex.org/W4243191819","https://openalex.org/W4245982154","https://openalex.org/W4249253717","https://openalex.org/W4290200763","https://openalex.org/W6779634530"],"related_works":["https://openalex.org/W2064724230","https://openalex.org/W2170230119","https://openalex.org/W2002895326","https://openalex.org/W3012647713","https://openalex.org/W2143216610","https://openalex.org/W2091800004","https://openalex.org/W2003870356","https://openalex.org/W2092295293","https://openalex.org/W2416045675","https://openalex.org/W1973504621"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":3},{"year":2025,"cited_by_count":6},{"year":2024,"cited_by_count":3},{"year":2023,"cited_by_count":2},{"year":2022,"cited_by_count":2},{"year":2021,"cited_by_count":6},{"year":2020,"cited_by_count":3},{"year":2019,"cited_by_count":5},{"year":2018,"cited_by_count":1},{"year":2017,"cited_by_count":7},{"year":2016,"cited_by_count":2},{"year":2015,"cited_by_count":5},{"year":2014,"cited_by_count":4},{"year":2013,"cited_by_count":2},{"year":2012,"cited_by_count":5}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}