{"id":"https://openalex.org/W2132300599","doi":null,"title":"On the regulation of immune responses to dietary and self antigens","display_name":"On the regulation of immune responses to dietary and self antigens","publication_year":2010,"publication_date":"2010-02-04","ids":{"openalex":"https://openalex.org/W2132300599","mag":"2132300599"},"language":"en","primary_location":{"id":"pmh:oai:gupea.ub.gu.se:2077/21532","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/2077/21532","pdf_url":"http://hdl.handle.net/2077/21532","source":{"id":"https://openalex.org/S4306401168","display_name":"Gothenburg University Publications Electronic Archive (Gothenburg University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I881427289","host_organization_name":"University of Gothenburg","host_organization_lineage":["https://openalex.org/I881427289"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Doctoral thesis"},"volume":null,"type":"dissertation","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"http://hdl.handle.net/2077/21532","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":null,"display_name":"Susanne Lindgr\u00e9n","orcid":"https://orcid.org/0000-0001-8705-9416","observed_orcids":["https://orcid.org/0000-0001-8705-9416"]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Susanne Lindgr\u00e9n","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0001-8705-9416","affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":true,"cited_by_count":1,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10031","display_name":"T-cell and B-cell Immunology","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10031","display_name":"T-cell and B-cell Immunology","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10580","display_name":"Immunotherapy and Immune Responses","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10469","display_name":"Psoriasis: Treatment and Pathogenesis","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/regulatory-t-cells","display_name":"regulatory T cells","score":0.8769999742507935},{"id":"https://openalex.org/keywords/cd4-cd25-regulatory-t-cells","display_name":"CD4+CD25+ T cells","score":0.906000018119812},{"id":"https://openalex.org/keywords/self-tolerance","display_name":"self-tolerance","score":0.6549999713897705},{"id":"https://openalex.org/keywords/oral-tolerance","display_name":"oral tolerance","score":0.9309999942779541},{"id":"https://openalex.org/keywords/myelin-oligodendrocyte-glycoprotein","display_name":"myelin oligodendrocyte glycoprotein","score":0.9509999752044678},{"id":"https://openalex.org/keywords/umbilical-cord-blood","display_name":"umbilical cord blood","score":0.8949999809265137},{"id":"https://openalex.org/keywords/celiac-lymph-nodes","display_name":"celiac lymph nodes","score":0.8970000147819519},{"id":"https://openalex.org/keywords/allergic-airway-inflammation","display_name":"allergic airway inflammation","score":0.8399999737739563},{"id":"https://openalex.org/keywords/intraepithelial-lymphocytes","display_name":"intraepithelial lymphocytes","score":0.9340000152587891},{"id":"https://openalex.org/keywords/commensal-microbiota","display_name":"commensal microbiota","score":0.734000027179718},{"id":"https://openalex.org/keywords/autoimmunity","display_name":"autoimmunity","score":0.4449999928474426}],"concepts":[{"id":"https://openalex.org/C79484868","wikidata":"https://www.wikidata.org/wiki/Q5971673","display_name":"IL-2 receptor","level":4,"score":0.7922530174255371},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.6996954679489136},{"id":"https://openalex.org/C147483822","wikidata":"https://www.wikidata.org/wiki/Q103537","display_name":"Antigen","level":2,"score":0.6641941070556641},{"id":"https://openalex.org/C8891405","wikidata":"https://www.wikidata.org/wiki/Q1059","display_name":"Immune system","level":2,"score":0.6008760929107666},{"id":"https://openalex.org/C2779357208","wikidata":"https://www.wikidata.org/wiki/Q6947292","display_name":"Myelin oligodendrocyte glycoprotein","level":4,"score":0.5760615468025208},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.5358753204345703},{"id":"https://openalex.org/C137061746","wikidata":"https://www.wikidata.org/wiki/Q736033","display_name":"Peripheral blood mononuclear cell","level":3,"score":0.5215960741043091},{"id":"https://openalex.org/C2780914630","wikidata":"https://www.wikidata.org/wiki/Q914952","display_name":"Cord blood","level":2,"score":0.4629304111003876},{"id":"https://openalex.org/C67662055","wikidata":"https://www.wikidata.org/wiki/Q1047791","display_name":"Antigen-presenting cell","level":4,"score":0.4326710104942322},{"id":"https://openalex.org/C2776090121","wikidata":"https://www.wikidata.org/wiki/Q193529","display_name":"T cell","level":3,"score":0.30457794666290283},{"id":"https://openalex.org/C2778486448","wikidata":"https://www.wikidata.org/wiki/Q494066","display_name":"Experimental autoimmune encephalomyelitis","level":3,"score":0.1336294710636139},{"id":"https://openalex.org/C202751555","wikidata":"https://www.wikidata.org/wiki/Q221681","display_name":"In vitro","level":2,"score":0.06203359365463257},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0553535521030426}],"mesh":[],"locations_count":2,"locations":[{"id":"pmh:oai:gupea.ub.gu.se:2077/21532","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/2077/21532","pdf_url":"http://hdl.handle.net/2077/21532","source":{"id":"https://openalex.org/S4306401168","display_name":"Gothenburg University Publications Electronic Archive (Gothenburg University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I881427289","host_organization_name":"University of Gothenburg","host_organization_lineage":["https://openalex.org/I881427289"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Doctoral thesis"},{"id":"mag:2132300599","doi":null,"is_oa":false,"landing_page_url":"https://gupea.ub.gu.se/bitstream/2077/21532/1/gupea_2077_21532_1.pdf","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":{"id":"pmh:oai:gupea.ub.gu.se:2077/21532","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/2077/21532","pdf_url":"http://hdl.handle.net/2077/21532","source":{"id":"https://openalex.org/S4306401168","display_name":"Gothenburg University Publications Electronic Archive (Gothenburg University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I881427289","host_organization_name":"University of Gothenburg","host_organization_lineage":["https://openalex.org/I881427289"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Doctoral thesis"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.98580002784729}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2132300599.pdf","grobid_xml":"https://content.openalex.org/works/W2132300599.grobid-xml"},"referenced_works_count":358,"referenced_works":["https://openalex.org/W27603634","https://openalex.org/W98240345","https://openalex.org/W105416253","https://openalex.org/W148987601","https://openalex.org/W173086023","https://openalex.org/W202393495","https://openalex.org/W233258589","https://openalex.org/W272430401","https://openalex.org/W326082147","https://openalex.org/W333385333","https://openalex.org/W1493510504","https://openalex.org/W1496011911","https://openalex.org/W1498193433","https://openalex.org/W1498371061","https://openalex.org/W1499169356","https://openalex.org/W1501795914","https://openalex.org/W1502413045","https://openalex.org/W1506354728","https://openalex.org/W1511335705","https://openalex.org/W1513084659","https://openalex.org/W1521289157","https://openalex.org/W1524217669","https://openalex.org/W1526518539","https://openalex.org/W1526621387","https://openalex.org/W1529780506","https://openalex.org/W1530044612","https://openalex.org/W1530782041","https://openalex.org/W1531330054","https://openalex.org/W1536322469","https://openalex.org/W1555988808","https://openalex.org/W1560064760","https://openalex.org/W1560277370","https://openalex.org/W1562592996","https://openalex.org/W1563526255","https://openalex.org/W1564760722","https://openalex.org/W1566167111","https://openalex.org/W1567420244","https://openalex.org/W1567647760","https://openalex.org/W1570190041","https://openalex.org/W1575585006","https://openalex.org/W1581904411","https://openalex.org/W1583728224","https://openalex.org/W1594227298","https://openalex.org/W1607420325","https://openalex.org/W1607622122","https://openalex.org/W1608108704","https://openalex.org/W1626276030","https://openalex.org/W1630880489","https://openalex.org/W1787048953","https://openalex.org/W1815644294","https://openalex.org/W1826394632","https://openalex.org/W1845975704","https://openalex.org/W1885335952","https://openalex.org/W1919005082","https://openalex.org/W1922717121","https://openalex.org/W1933752105","https://openalex.org/W1954536138","https://openalex.org/W1960226482","https://openalex.org/W1960538598","https://openalex.org/W1961184285","https://openalex.org/W1962132325","https://openalex.org/W1963832008","https://openalex.org/W1964010927","https://openalex.org/W1964674962","https://openalex.org/W1965727970","https://openalex.org/W1966073503","https://openalex.org/W1967348106","https://openalex.org/W1968274103","https://openalex.org/W1968346082","https://openalex.org/W1968459329","https://openalex.org/W1968973375","https://openalex.org/W1970376806","https://openalex.org/W1972362434","https://openalex.org/W1973834362","https://openalex.org/W1974209230","https://openalex.org/W1975634520","https://openalex.org/W1977043186","https://openalex.org/W1977880576","https://openalex.org/W1979049274","https://openalex.org/W1979130190","https://openalex.org/W1980287697","https://openalex.org/W1981004692","https://openalex.org/W1981178699","https://openalex.org/W1981355586","https://openalex.org/W1981846896","https://openalex.org/W1982051091","https://openalex.org/W1983041370","https://openalex.org/W1983279369","https://openalex.org/W1983675151","https://openalex.org/W1984127959","https://openalex.org/W1985413676","https://openalex.org/W1986014527","https://openalex.org/W1986216579","https://openalex.org/W1986321004","https://openalex.org/W1986497597","https://openalex.org/W1988317772","https://openalex.org/W1988899741","https://openalex.org/W1989694037","https://openalex.org/W1990236675","https://openalex.org/W1992153121","https://openalex.org/W1992985178","https://openalex.org/W1993826234","https://openalex.org/W1994416240","https://openalex.org/W1996109184","https://openalex.org/W1996289177","https://openalex.org/W1996615467","https://openalex.org/W1996828163","https://openalex.org/W1998240361","https://openalex.org/W1998603634","https://openalex.org/W1999227421","https://openalex.org/W2001482660","https://openalex.org/W2002726220","https://openalex.org/W2002726823","https://openalex.org/W2003652884","https://openalex.org/W2003774992","https://openalex.org/W2004282938","https://openalex.org/W2004708987","https://openalex.org/W2004828548","https://openalex.org/W2005096752","https://openalex.org/W2005896211","https://openalex.org/W2005993715","https://openalex.org/W2007223760","https://openalex.org/W2007362831","https://openalex.org/W2009209517","https://openalex.org/W2009596665","https://openalex.org/W2011208835","https://openalex.org/W2011650977","https://openalex.org/W2012123709","https://openalex.org/W2013436886","https://openalex.org/W2013669353","https://openalex.org/W2014591244","https://openalex.org/W2015085911","https://openalex.org/W2015680329","https://openalex.org/W2016827757","https://openalex.org/W2018249790","https://openalex.org/W2018460760","https://openalex.org/W2018463927","https://openalex.org/W2018546175","https://openalex.org/W2018584013","https://openalex.org/W2018703348","https://openalex.org/W2021234462","https://openalex.org/W2022221509","https://openalex.org/W2022898836","https://openalex.org/W2024251508","https://openalex.org/W2024263435","https://openalex.org/W2024351056","https://openalex.org/W2024511093","https://openalex.org/W2025114863","https://openalex.org/W2026426963","https://openalex.org/W2026891958","https://openalex.org/W2027606763","https://openalex.org/W2029097259","https://openalex.org/W2030346758","https://openalex.org/W2031247425","https://openalex.org/W2031325281","https://openalex.org/W2031551895","https://openalex.org/W2032218738","https://openalex.org/W2032311934","https://openalex.org/W2032372422","https://openalex.org/W2033313264","https://openalex.org/W2033918621","https://openalex.org/W2034402052","https://openalex.org/W2035661165","https://openalex.org/W2035875673","https://openalex.org/W2036383793","https://openalex.org/W2036419095","https://openalex.org/W2037127090","https://openalex.org/W2037259928","https://openalex.org/W2037920661","https://openalex.org/W2039047676","https://openalex.org/W2039198873","https://openalex.org/W2039672885","https://openalex.org/W2041266914","https://openalex.org/W2041636563","https://openalex.org/W2043796257","https://openalex.org/W2044035130","https://openalex.org/W2044069347","https://openalex.org/W2044763085","https://openalex.org/W2045893773","https://openalex.org/W2047378679","https://openalex.org/W2047971908","https://openalex.org/W2048284808","https://openalex.org/W2051447573","https://openalex.org/W2052086128","https://openalex.org/W2052707632","https://openalex.org/W2052969143","https://openalex.org/W2054974176","https://openalex.org/W2055061339","https://openalex.org/W2056951227","https://openalex.org/W2059377172","https://openalex.org/W2061071534","https://openalex.org/W2062619192","https://openalex.org/W2062632117","https://openalex.org/W2066432115","https://openalex.org/W2066687204","https://openalex.org/W2066728727","https://openalex.org/W2067223437","https://openalex.org/W2068331312","https://openalex.org/W2068412205","https://openalex.org/W2068639447","https://openalex.org/W2070213858","https://openalex.org/W2071244293","https://openalex.org/W2071360012","https://openalex.org/W2071625815","https://openalex.org/W2072077104","https://openalex.org/W2072447036","https://openalex.org/W2073636322","https://openalex.org/W2074575630","https://openalex.org/W2074923464","https://openalex.org/W2075625373","https://openalex.org/W2076067786","https://openalex.org/W2076173157","https://openalex.org/W2076819781","https://openalex.org/W2077253809","https://openalex.org/W2079156182","https://openalex.org/W2079314155","https://openalex.org/W2079439641","https://openalex.org/W2079517510","https://openalex.org/W2079721061","https://openalex.org/W2080735658","https://openalex.org/W2080879611","https://openalex.org/W2080890675","https://openalex.org/W2082573029","https://openalex.org/W2085923448","https://openalex.org/W2086456032","https://openalex.org/W2088553840","https://openalex.org/W2089004438","https://openalex.org/W2089971935","https://openalex.org/W2090857694","https://openalex.org/W2091639781","https://openalex.org/W2092325349","https://openalex.org/W2092613694","https://openalex.org/W2092905533","https://openalex.org/W2093302170","https://openalex.org/W2094605832","https://openalex.org/W2095146135","https://openalex.org/W2096423439","https://openalex.org/W2096696255","https://openalex.org/W2097811455","https://openalex.org/W2098157239","https://openalex.org/W2098479780","https://openalex.org/W2099221638","https://openalex.org/W2100051740","https://openalex.org/W2101230909","https://openalex.org/W2102505588","https://openalex.org/W2104348703","https://openalex.org/W2104374116","https://openalex.org/W2107085495","https://openalex.org/W2107240342","https://openalex.org/W2107486259","https://openalex.org/W2107631420","https://openalex.org/W2108685327","https://openalex.org/W2109708356","https://openalex.org/W2109923158","https://openalex.org/W2110201516","https://openalex.org/W2110381465","https://openalex.org/W2110753254","https://openalex.org/W2110957620","https://openalex.org/W2111322617","https://openalex.org/W2112866067","https://openalex.org/W2114208164","https://openalex.org/W2114216755","https://openalex.org/W2118268169","https://openalex.org/W2120010406","https://openalex.org/W2123534496","https://openalex.org/W2123832847","https://openalex.org/W2123987776","https://openalex.org/W2125095112","https://openalex.org/W2125311191","https://openalex.org/W2128211931","https://openalex.org/W2128414133","https://openalex.org/W2129112743","https://openalex.org/W2129767277","https://openalex.org/W2130822830","https://openalex.org/W2131406530","https://openalex.org/W2131633419","https://openalex.org/W2132603657","https://openalex.org/W2132929600","https://openalex.org/W2133088091","https://openalex.org/W2133972276","https://openalex.org/W2134364025","https://openalex.org/W2134591209","https://openalex.org/W2135180612","https://openalex.org/W2135280067","https://openalex.org/W2136135274","https://openalex.org/W2136273066","https://openalex.org/W2137482508","https://openalex.org/W2138961639","https://openalex.org/W2139019810","https://openalex.org/W2139191751","https://openalex.org/W2139847828","https://openalex.org/W2141116067","https://openalex.org/W2141231618","https://openalex.org/W2141357989","https://openalex.org/W2142269895","https://openalex.org/W2142490832","https://openalex.org/W2143274206","https://openalex.org/W2144836936","https://openalex.org/W2145043041","https://openalex.org/W2145164692","https://openalex.org/W2146942722","https://openalex.org/W2147006149","https://openalex.org/W2147018917","https://openalex.org/W2147389132","https://openalex.org/W2148096192","https://openalex.org/W2148222156","https://openalex.org/W2148226248","https://openalex.org/W2148806075","https://openalex.org/W2149497184","https://openalex.org/W2150079601","https://openalex.org/W2150178223","https://openalex.org/W2150453791","https://openalex.org/W2150680520","https://openalex.org/W2150747144","https://openalex.org/W2153006156","https://openalex.org/W2153603820","https://openalex.org/W2155366992","https://openalex.org/W2155779547","https://openalex.org/W2156959273","https://openalex.org/W2156964052","https://openalex.org/W2157907412","https://openalex.org/W2158200061","https://openalex.org/W2158676170","https://openalex.org/W2158715209","https://openalex.org/W2159012191","https://openalex.org/W2159401396","https://openalex.org/W2159768658","https://openalex.org/W2159987448","https://openalex.org/W2160752278","https://openalex.org/W2161354474","https://openalex.org/W2161450196","https://openalex.org/W2161545566","https://openalex.org/W2161939265","https://openalex.org/W2164386060","https://openalex.org/W2165185978","https://openalex.org/W2165214298","https://openalex.org/W2166819611","https://openalex.org/W2168419126","https://openalex.org/W2168491130","https://openalex.org/W2168628806","https://openalex.org/W2168662343","https://openalex.org/W2168985658","https://openalex.org/W2169233545","https://openalex.org/W2170433803","https://openalex.org/W2171398137","https://openalex.org/W2171980652","https://openalex.org/W2275932066","https://openalex.org/W2325999030","https://openalex.org/W2331474297","https://openalex.org/W2342314812","https://openalex.org/W2395660240","https://openalex.org/W2408223790","https://openalex.org/W2411016700","https://openalex.org/W2418956879","https://openalex.org/W2464573478","https://openalex.org/W4297695735","https://openalex.org/W4313310664","https://openalex.org/W4313379132"],"related_works":["https://openalex.org/W1977180934","https://openalex.org/W1597774099","https://openalex.org/W2032372422","https://openalex.org/W1979982823","https://openalex.org/W579568480","https://openalex.org/W7096704794","https://openalex.org/W2162819001","https://openalex.org/W1514200102","https://openalex.org/W2098479780","https://openalex.org/W2356812690"],"abstract_inverted_index":{"Regulatory":[0],"mechanisms":[1],"are":[2,25,98,170,387],"necessary":[3],"to":[4,88,107,157,223,245,327,378,398,438,463,469],"avoid":[5],"the":[6,13,71,86,103,124,134,151,167,175,211,216,235,241,259,277,287,316,368,376,390,404,472],"misdirected":[7],"aggressive":[8],"immune":[9],"responses":[10,37,106],"responsible":[11],"for":[12,27,153,240],"pathology":[14],"seen":[15],"in":[16,38,70,102,117,150,155,189,215,234,251,286,339,389,425],"autoimmunity":[17],"and":[18,42,67,132,164,178,300,318,324,380,419,447],"allergy.":[19],"Thymic-derived":[20],"CD4+CD25+":[21,33],"regulatory":[22,129,144,181,213,231],"T":[23,51,115,130,182,187,207,232],"cells":[24,52,84,97,116,131,138,142,183,188,208,233,374,454],"indispensible":[26],"this":[28],"regulation.":[29],"We":[30,78,109,173,292],"investigated":[31,271],"if":[32],"Treg":[34],"prevents":[35],"auto-reactive":[36],"adult":[39,81],"peripheral":[40,55],"blood":[41,56,95],"cord":[43,61,94],"blood.":[44],"Mononuclear":[45],"cells,":[46],"as":[47,49],"well":[48],"CD4+":[50,186,206],"isolated":[53,402],"from":[54,60,184,276,298,341,403,452],"of":[57,75,105,113,126,136,166,180,196,204,230,243,258,266,290,296,313,322,335,357,363,429,459],"adults":[58],"or":[59,73],"blood,":[62],"were":[63,303,412,436,461,467],"stimulated":[64,455],"with":[65,143,310,332,456],"self-antigens":[66],"recall":[68],"antigens":[69,383],"absence":[72],"presence":[74,125],"CD25+":[76,83,96,128],"cells.":[77],"demonstrate":[79],"that":[80,111,133,228,294,348,392],"human":[82],"regulate":[85],"response":[87,156],"myelin":[89],"oligodendrocyte":[90],"glycoprotein":[91],"(MOG),":[92],"while":[93],"not":[99],"equally":[100],"efficient":[101],"inhibition":[104],"self-antigens.":[108],"conclude":[110],"activation":[112,177,362],"self-reactive":[114],"normal":[118],"healthy":[119],"individuals":[120],"is":[121,249],"prevented":[122],"by":[123,353,414],"self-antigen-specific":[127],"majority":[135],"these":[137],"mature":[139],"after":[140],"birth.\\nT":[141],"properties":[145],"can":[146],"also":[147],"be":[148,238],"induced":[149],"periphery,":[152],"example":[154],"a":[158,197,256,263,273,426],"fed":[159],"antigen.":[160,199],"The":[161,434],"physiological":[162],"requirements":[163],"localization":[165],"tolerance":[168,244,248,352,395],"induction":[169,179,229],"largely":[171],"unknown.":[172],"studied":[174],"antigen-specific":[176,205,394],"na\u00efve":[185,399,464],"different":[190],"lymphoid":[191],"compartments":[192],"following":[193],"oral":[194,351],"administration":[195],"protein":[198],"A":[200,283],"significantly":[201],"higher":[202],"proportion":[203],"developed":[209],"into":[210,315,384],"putative":[212],"phenotype":[214],"liver-draining":[217],"celiac":[218],"lymph":[219],"node":[220],"(CLN),":[221],"compared":[222,326],"other":[224],"sites.":[225],"This":[226,329],"suggests":[227],"CLN":[236],"may":[237],"relevant":[239],"generation":[242],"dietary":[246,358],"antigens.\\nOral":[247],"impaired":[250],"germfree":[252],"animals,":[253],"which":[254,386],"indicates":[255],"role":[257],"enteric":[260],"flora.":[261],"Using":[262],"mouse":[264,427],"model":[265,428],"allergic":[267,307,431,473],"airway":[268,308,432],"inflammation,":[269],"we":[270],"how":[272],"natural":[274],"adjuvant":[275],"commensal":[278],"microflora,":[279],"Staphylococcus":[280],"aureus":[281],"enterotoxin":[282],"(SEA),":[284],"aids":[285],"tolerogenic":[288,355],"processing":[289,356],"antigens.":[291],"found":[293,388,437],"recipients":[295],"serum":[297],"SEA-treated":[299],"ovalbumin-fed":[301],"donors":[302],"better":[304],"protected":[305],"against":[306],"inflammation":[309],"diminished":[311],"influx":[312],"eosinophils":[314],"lungs":[317],"reduced":[319],"antigen-induced":[320],"production":[321],"interleukin-5":[323],"interleukin-13":[325],"controls.":[328],"was":[330,423],"associated":[331],"increased":[333],"density":[334],"CD8\u03b1+":[336],"intraepithelial":[337,364],"lymphocytes":[338,365],"gut-sections":[340],"SEA":[342,349],"treated":[343],"donors.":[344],"Our":[345],"results":[346],"suggest":[347],"promotes":[350],"facilitating":[354],"antigens,":[359],"possibly":[360],"via":[361],"acting":[366],"on":[367],"absorptive":[369],"intestinal":[370,407],"epithelium.":[371],"\\nIntestinal":[372],"epithelial":[373,408],"have":[375],"capacity":[377,422],"sample":[379],"package":[381],"environmental":[382],"exosomes,":[385],"serum-fraction":[391],"mediates":[393],"when":[396],"transferred":[397],"recipients.":[400],"Exosomes":[401],"murine":[405],"small":[406],"cell":[409],"line":[410],"IEC4.1":[411,453],"characterized":[413],"flow":[415],"cytometry,":[416],"electron":[417],"microscopy":[418],"their":[420],"immunomodulatory":[421],"explored":[424],"ovalbumin-induced":[430],"inflammation.":[433],"exosomes":[435,451],"carry":[439],"MHC":[440,443],"class":[441,444],"I,":[442],"II,":[445],"CD9":[446],"MFGE-8.":[448],"When":[449],"antigen-pulsed":[450],"low":[457],"level":[458],"IFN-\u03b3":[460],"given":[462],"mice":[465],"they":[466],"able":[468],"partly":[470],"prevent":[471],"sensitisation.":[474]},"counts_by_year":[{"year":2013,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}
