{"id":"https://openalex.org/W2131990449","doi":"https://doi.org/10.1194/jlr.p007476","title":"Effects of genetic variants on lipid parameters and dyslipidemia in a Chinese population","display_name":"Effects of genetic variants on lipid parameters and dyslipidemia in a Chinese population","publication_year":2010,"publication_date":"2010-12-13","ids":{"openalex":"https://openalex.org/W2131990449","doi":"https://doi.org/10.1194/jlr.p007476","mag":"2131990449","pmid":"https://pubmed.ncbi.nlm.nih.gov/21149302","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/3023556"},"language":"en","primary_location":{"id":"doi:10.1194/jlr.p007476","doi":"https://doi.org/10.1194/jlr.p007476","is_oa":true,"landing_page_url":"https://doi.org/10.1194/jlr.p007476","pdf_url":null,"source":{"id":"https://openalex.org/S11400418","display_name":"Journal of Lipid Research","issn_l":"0022-2275","issn":["0022-2275","1539-7262"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-140","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Lipid Research","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://doi.org/10.1194/jlr.p007476","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5100321915","display_name":"Yun Liu","orcid":"https://orcid.org/0000-0001-5753-1265","observed_orcids":["https://orcid.org/0000-0001-5753-1265","https://orcid.org/0009-0000-5774-4893"]},"institutions":[{"id":"https://openalex.org/I24943067","display_name":"Fudan University","ror":"https://ror.org/013q1eq08","country_code":"CN","type":"education","lineage":["https://openalex.org/I24943067"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yun Liu","raw_affiliation_strings":["Institutes of Biomedical Sciences, Fudan University, Shanghai, PR China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institutes of Biomedical Sciences, Fudan University, Shanghai, PR China","institution_ids":["https://openalex.org/I24943067"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5074883511","display_name":"Daizhan Zhou","orcid":"https://orcid.org/0000-0001-9104-2801","observed_orcids":["https://orcid.org/0000-0001-9104-2801"]},"institutions":[{"id":"https://openalex.org/I19820366","display_name":"Chinese Academy of Sciences","ror":"https://ror.org/034t30j35","country_code":"CN","type":"government","lineage":["https://openalex.org/I19820366"]},{"id":"https://openalex.org/I24943067","display_name":"Fudan University","ror":"https://ror.org/013q1eq08","country_code":"CN","type":"education","lineage":["https://openalex.org/I24943067"]},{"id":"https://openalex.org/I4210106477","display_name":"Shanghai Institutes for Biological Sciences","ror":"https://ror.org/011rf9d86","country_code":"CN","type":"facility","lineage":["https://openalex.org/I19820366","https://openalex.org/I4210106477"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Daizhan Zhou","raw_affiliation_strings":["Institute for Nutritional Sciences, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai, PR China","Institutes of Biomedical Sciences, Fudan University, Shanghai, PR China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute for Nutritional Sciences, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai, PR China","institution_ids":["https://openalex.org/I19820366","https://openalex.org/I4210106477"]},{"raw_affiliation_string":"Institutes of Biomedical Sciences, Fudan University, Shanghai, PR China","institution_ids":["https://openalex.org/I24943067"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100397155","display_name":"Zhou Zhang","orcid":"https://orcid.org/0000-0001-9525-6938","observed_orcids":["https://orcid.org/0000-0001-9525-6938","https://orcid.org/0000-0002-3935-6819","https://orcid.org/0000-0003-3814-3093","https://orcid.org/0009-0005-6135-0084","https://orcid.org/0009-0006-4474-6367"]},"institutions":[{"id":"https://openalex.org/I19820366","display_name":"Chinese Academy of Sciences","ror":"https://ror.org/034t30j35","country_code":"CN","type":"government","lineage":["https://openalex.org/I19820366"]},{"id":"https://openalex.org/I24943067","display_name":"Fudan University","ror":"https://ror.org/013q1eq08","country_code":"CN","type":"education","lineage":["https://openalex.org/I24943067"]},{"id":"https://openalex.org/I4210106477","display_name":"Shanghai Institutes for Biological Sciences","ror":"https://ror.org/011rf9d86","country_code":"CN","type":"facility","lineage":["https://openalex.org/I19820366","https://openalex.org/I4210106477"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Zhou Zhang","raw_affiliation_strings":["Institute for Nutritional Sciences, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai, PR China","Institutes of Biomedical Sciences, Fudan University, Shanghai, PR China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute for Nutritional Sciences, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai, PR China","institution_ids":["https://openalex.org/I19820366","https://openalex.org/I4210106477"]},{"raw_affiliation_string":"Institutes of Biomedical Sciences, Fudan University, Shanghai, PR China","institution_ids":["https://openalex.org/I24943067"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5046425563","display_name":"Yiqing Song","orcid":"https://orcid.org/0000-0002-2097-7332","observed_orcids":["https://orcid.org/0000-0002-2097-7332","https://orcid.org/0000-0003-3642-6778"]},"institutions":[{"id":"https://openalex.org/I1283280774","display_name":"Brigham and Women's Hospital","ror":"https://ror.org/04b6nzv94","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I121934306","https://openalex.org/I1283280774","https://openalex.org/I48633490"]},{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Yiqing Song","raw_affiliation_strings":["Division of Preventive Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Preventive Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA","institution_ids":["https://openalex.org/I1283280774","https://openalex.org/I136199984"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100366358","display_name":"Di Zhang","orcid":"https://orcid.org/0000-0001-5586-1527","observed_orcids":["https://orcid.org/0000-0001-5586-1527"]},"institutions":[{"id":"https://openalex.org/I183067930","display_name":"Shanghai Jiao Tong University","ror":"https://ror.org/0220qvk04","country_code":"CN","type":"education","lineage":["https://openalex.org/I183067930"]},{"id":"https://openalex.org/I19820366","display_name":"Chinese Academy of Sciences","ror":"https://ror.org/034t30j35","country_code":"CN","type":"government","lineage":["https://openalex.org/I19820366"]},{"id":"https://openalex.org/I4210106477","display_name":"Shanghai Institutes for Biological Sciences","ror":"https://ror.org/011rf9d86","country_code":"CN","type":"facility","lineage":["https://openalex.org/I19820366","https://openalex.org/I4210106477"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Di Zhang","raw_affiliation_strings":["Bio-X Center, Key Laboratory for the Genetics of Developmental and Neuropsychiatric Disorders (Ministry of Education), Shanghai Jiao Tong University, Shanghai, PR China","Institute for Nutritional Sciences, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai, PR China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Bio-X Center, Key Laboratory for the Genetics of Developmental and Neuropsychiatric Disorders (Ministry of Education), Shanghai Jiao Tong University, Shanghai, PR China","institution_ids":["https://openalex.org/I183067930"]},{"raw_affiliation_string":"Institute for Nutritional Sciences, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai, PR China","institution_ids":["https://openalex.org/I19820366","https://openalex.org/I4210106477"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5114664722","display_name":"Teng Zhao","orcid":"https://orcid.org/0009-0009-8717-8955","observed_orcids":["https://orcid.org/0009-0009-8717-8955"]},"institutions":[{"id":"https://openalex.org/I19820366","display_name":"Chinese Academy of Sciences","ror":"https://ror.org/034t30j35","country_code":"CN","type":"government","lineage":["https://openalex.org/I19820366"]},{"id":"https://openalex.org/I4210106477","display_name":"Shanghai Institutes for Biological Sciences","ror":"https://ror.org/011rf9d86","country_code":"CN","type":"facility","lineage":["https://openalex.org/I19820366","https://openalex.org/I4210106477"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Teng Zhao","raw_affiliation_strings":["Institute for Nutritional Sciences, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai, PR China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute for Nutritional Sciences, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai, PR China","institution_ids":["https://openalex.org/I19820366","https://openalex.org/I4210106477"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5019160081","display_name":"Zhuo Chen","orcid":"https://orcid.org/0000-0003-1460-7367","observed_orcids":["https://orcid.org/0000-0003-1460-7367","https://orcid.org/0000-0001-5655-5695"]},"institutions":[{"id":"https://openalex.org/I19820366","display_name":"Chinese Academy of Sciences","ror":"https://ror.org/034t30j35","country_code":"CN","type":"government","lineage":["https://openalex.org/I19820366"]},{"id":"https://openalex.org/I4210106477","display_name":"Shanghai Institutes for Biological Sciences","ror":"https://ror.org/011rf9d86","country_code":"CN","type":"facility","lineage":["https://openalex.org/I19820366","https://openalex.org/I4210106477"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Zhuo Chen","raw_affiliation_strings":["Institute for Nutritional Sciences, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai, PR China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute for Nutritional Sciences, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai, PR China","institution_ids":["https://openalex.org/I19820366","https://openalex.org/I4210106477"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Yun Sun","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210086405","display_name":"National Institute of Biological Sciences, Beijing","ror":"https://ror.org/00wksha49","country_code":"CN","type":"facility","lineage":["https://openalex.org/I4210086405"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yun Sun","raw_affiliation_strings":["National Institute of Biological Sciences, Beijing, PR China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"National Institute of Biological Sciences, Beijing, PR China","institution_ids":["https://openalex.org/I4210086405"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101447281","display_name":"Dabing Zhang","orcid":"https://orcid.org/0000-0003-3181-9812","observed_orcids":["https://orcid.org/0000-0003-3181-9812","https://orcid.org/0000-0002-1764-2929"]},"institutions":[{"id":"https://openalex.org/I183067930","display_name":"Shanghai Jiao Tong University","ror":"https://ror.org/0220qvk04","country_code":"CN","type":"education","lineage":["https://openalex.org/I183067930"]},{"id":"https://openalex.org/I19820366","display_name":"Chinese Academy of Sciences","ror":"https://ror.org/034t30j35","country_code":"CN","type":"government","lineage":["https://openalex.org/I19820366"]},{"id":"https://openalex.org/I4210106477","display_name":"Shanghai Institutes for Biological Sciences","ror":"https://ror.org/011rf9d86","country_code":"CN","type":"facility","lineage":["https://openalex.org/I19820366","https://openalex.org/I4210106477"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Dabing Zhang","raw_affiliation_strings":["Bio-X Center, Key Laboratory for the Genetics of Developmental and Neuropsychiatric Disorders (Ministry of Education), Shanghai Jiao Tong University, Shanghai, PR China","Institute for Nutritional Sciences, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai, PR China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Bio-X Center, Key Laboratory for the Genetics of Developmental and Neuropsychiatric Disorders (Ministry of Education), Shanghai Jiao Tong University, Shanghai, PR China","institution_ids":["https://openalex.org/I183067930"]},{"raw_affiliation_string":"Institute for Nutritional Sciences, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai, PR China","institution_ids":["https://openalex.org/I19820366","https://openalex.org/I4210106477"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5006262914","display_name":"Yifeng Yang","orcid":"https://orcid.org/0000-0002-9796-8979","observed_orcids":["https://orcid.org/0000-0002-9796-8979"]},"institutions":[{"id":"https://openalex.org/I19820366","display_name":"Chinese Academy of Sciences","ror":"https://ror.org/034t30j35","country_code":"CN","type":"government","lineage":["https://openalex.org/I19820366"]},{"id":"https://openalex.org/I4210106477","display_name":"Shanghai Institutes for Biological Sciences","ror":"https://ror.org/011rf9d86","country_code":"CN","type":"facility","lineage":["https://openalex.org/I19820366","https://openalex.org/I4210106477"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yifeng Yang","raw_affiliation_strings":["Institute for Nutritional Sciences, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai, PR China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute for Nutritional Sciences, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai, PR China","institution_ids":["https://openalex.org/I19820366","https://openalex.org/I4210106477"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5002251300","display_name":"Qinghe Xing","orcid":"https://orcid.org/0000-0003-1780-4761","observed_orcids":["https://orcid.org/0000-0003-1780-4761","https://orcid.org/0000-0002-9916-8254"]},"institutions":[{"id":"https://openalex.org/I24943067","display_name":"Fudan University","ror":"https://ror.org/013q1eq08","country_code":"CN","type":"education","lineage":["https://openalex.org/I24943067"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Qinghe Xing","raw_affiliation_strings":["Institutes of Biomedical Sciences, Fudan University, Shanghai, PR China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institutes of Biomedical Sciences, Fudan University, Shanghai, PR China","institution_ids":["https://openalex.org/I24943067"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5010215560","display_name":"Xinzhi Zhao","orcid":"https://orcid.org/0000-0002-8763-2785","observed_orcids":["https://orcid.org/0000-0002-8763-2785"]},"institutions":[{"id":"https://openalex.org/I24943067","display_name":"Fudan University","ror":"https://ror.org/013q1eq08","country_code":"CN","type":"education","lineage":["https://openalex.org/I24943067"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xinzhi Zhao","raw_affiliation_strings":["Institutes of Biomedical Sciences, Fudan University, Shanghai, PR China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institutes of Biomedical Sciences, Fudan University, Shanghai, PR China","institution_ids":["https://openalex.org/I24943067"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5001089259","display_name":"He Xu","orcid":"https://orcid.org/0000-0001-6559-2957","observed_orcids":["https://orcid.org/0000-0001-6559-2957"]},"institutions":[{"id":"https://openalex.org/I19820366","display_name":"Chinese Academy of Sciences","ror":"https://ror.org/034t30j35","country_code":"CN","type":"government","lineage":["https://openalex.org/I19820366"]},{"id":"https://openalex.org/I4210106477","display_name":"Shanghai Institutes for Biological Sciences","ror":"https://ror.org/011rf9d86","country_code":"CN","type":"facility","lineage":["https://openalex.org/I19820366","https://openalex.org/I4210106477"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"He Xu","raw_affiliation_strings":["Institute for Nutritional Sciences, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai, PR China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute for Nutritional Sciences, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai, PR China","institution_ids":["https://openalex.org/I19820366","https://openalex.org/I4210106477"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5102798483","display_name":"Lin He","orcid":"https://orcid.org/0000-0003-1079-1195","observed_orcids":["https://orcid.org/0000-0003-1079-1195","https://orcid.org/0009-0004-0487-1636"]},"institutions":[{"id":"https://openalex.org/I183067930","display_name":"Shanghai Jiao Tong University","ror":"https://ror.org/0220qvk04","country_code":"CN","type":"education","lineage":["https://openalex.org/I183067930"]},{"id":"https://openalex.org/I19820366","display_name":"Chinese Academy of Sciences","ror":"https://ror.org/034t30j35","country_code":"CN","type":"government","lineage":["https://openalex.org/I19820366"]},{"id":"https://openalex.org/I24943067","display_name":"Fudan University","ror":"https://ror.org/013q1eq08","country_code":"CN","type":"education","lineage":["https://openalex.org/I24943067"]},{"id":"https://openalex.org/I4210106477","display_name":"Shanghai Institutes for Biological Sciences","ror":"https://ror.org/011rf9d86","country_code":"CN","type":"facility","lineage":["https://openalex.org/I19820366","https://openalex.org/I4210106477"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Lin He","raw_affiliation_strings":["Bio-X Center, Key Laboratory for the Genetics of Developmental and Neuropsychiatric Disorders (Ministry of Education), Shanghai Jiao Tong University, Shanghai, PR China","Institute for Nutritional Sciences, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai, PR China","Institutes of Biomedical Sciences, Fudan University, Shanghai, PR China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Bio-X Center, Key Laboratory for the Genetics of Developmental and Neuropsychiatric Disorders (Ministry of Education), Shanghai Jiao Tong University, Shanghai, PR China","institution_ids":["https://openalex.org/I183067930"]},{"raw_affiliation_string":"Institute for Nutritional Sciences, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai, PR China","institution_ids":["https://openalex.org/I19820366","https://openalex.org/I4210106477"]},{"raw_affiliation_string":"Institutes of Biomedical Sciences, Fudan University, Shanghai, PR China","institution_ids":["https://openalex.org/I24943067"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":7,"corresponding_author_ids":["https://openalex.org/A5102798483"],"corresponding_institution_ids":["https://openalex.org/I183067930","https://openalex.org/I19820366","https://openalex.org/I24943067","https://openalex.org/I4210106477"],"apc_list":{"value":3430,"currency":"USD","value_usd":3430},"apc_paid":{"value":3430,"currency":"USD","value_usd":3430},"fwci":1.1117,"has_fulltext":false,"cited_by_count":55,"citation_normalized_percentile":{"value":0.7793982,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":93,"max":99},"biblio":{"volume":"52","issue":"2","first_page":"354","last_page":"360"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10261","display_name":"Genetic Associations and Epidemiology","score":0.9038000106811523,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10261","display_name":"Genetic Associations and Epidemiology","score":0.9038000106811523,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10394","display_name":"Lipoproteins and Cardiovascular Health","score":0.031300000846385956,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T13430","display_name":"Lipid metabolism and disorders","score":0.030500000342726707,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/dyslipidemia","display_name":"dyslipidemia","score":0.8130000233650208},{"id":"https://openalex.org/keywords/plasma-lipid-levels","display_name":"plasma lipid levels","score":0.6859999895095825},{"id":"https://openalex.org/keywords/single-nucleotide-polymorphisms","display_name":"single nucleotide polymorphisms","score":0.8830000162124634},{"id":"https://openalex.org/keywords/genetic-association","display_name":"genetic association","score":0.6359999775886536},{"id":"https://openalex.org/keywords/han-chinese","display_name":"Han Chinese","score":0.7950000166893005},{"id":"https://openalex.org/keywords/total-cholesterol","display_name":"total cholesterol","score":0.8420000076293945},{"id":"https://openalex.org/keywords/triglycerides","display_name":"triglycerides","score":0.9549999833106995},{"id":"https://openalex.org/keywords/hdl-cholesterol","display_name":"HDL cholesterol","score":0.9700000286102295},{"id":"https://openalex.org/keywords/ldl-cholesterol","display_name":"LDL cholesterol","score":1.0},{"id":"https://openalex.org/keywords/lipoprotein-metabolism","display_name":"lipoprotein metabolism","score":0.5619999766349792}],"concepts":[{"id":"https://openalex.org/C153209595","wikidata":"https://www.wikidata.org/wiki/Q501128","display_name":"Single-nucleotide polymorphism","level":4,"score":0.7301093339920044},{"id":"https://openalex.org/C106208931","wikidata":"https://www.wikidata.org/wiki/Q1098876","display_name":"Genome-wide association study","level":5,"score":0.676658034324646},{"id":"https://openalex.org/C2778096610","wikidata":"https://www.wikidata.org/wiki/Q1476525","display_name":"Dyslipidemia","level":3,"score":0.6535850167274475},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.5370439887046814},{"id":"https://openalex.org/C186413461","wikidata":"https://www.wikidata.org/wiki/Q744727","display_name":"Genetic association","level":5,"score":0.5044032335281372},{"id":"https://openalex.org/C2908647359","wikidata":"https://www.wikidata.org/wiki/Q2625603","display_name":"Population","level":2,"score":0.4747120440006256},{"id":"https://openalex.org/C2780221984","wikidata":"https://www.wikidata.org/wiki/Q131191","display_name":"Body mass index","level":2,"score":0.4687640368938446},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.46359390020370483},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.4586924910545349},{"id":"https://openalex.org/C2778163477","wikidata":"https://www.wikidata.org/wiki/Q43656","display_name":"Cholesterol","level":2,"score":0.4304085075855255},{"id":"https://openalex.org/C135763542","wikidata":"https://www.wikidata.org/wiki/Q106016","display_name":"Genotype","level":3,"score":0.3543778657913208},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.3320286273956299},{"id":"https://openalex.org/C555293320","wikidata":"https://www.wikidata.org/wiki/Q12206","display_name":"Diabetes mellitus","level":2,"score":0.3064974546432495},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.2218499481678009},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.1265893578529358},{"id":"https://openalex.org/C99454951","wikidata":"https://www.wikidata.org/wiki/Q932068","display_name":"Environmental health","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000369","descriptor_name":"Aged, 80 and over","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008055","descriptor_name":"Lipids","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020641","descriptor_name":"Polymorphism, Single Nucleotide","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D044466","descriptor_name":"Asian People","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D050171","descriptor_name":"Dyslipidemias","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D050356","descriptor_name":"Lipid Metabolism","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true}],"locations_count":5,"locations":[{"id":"doi:10.1194/jlr.p007476","doi":"https://doi.org/10.1194/jlr.p007476","is_oa":true,"landing_page_url":"https://doi.org/10.1194/jlr.p007476","pdf_url":null,"source":{"id":"https://openalex.org/S11400418","display_name":"Journal of Lipid Research","issn_l":"0022-2275","issn":["0022-2275","1539-7262"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-140","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Lipid Research","raw_type":"journal-article"},{"id":"pmh:oai:europepmc.org:2273985","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3023556","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:3023556","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3023556","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"J Lipid Res","raw_type":"Text"},{"id":"pmid:21149302","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/21149302","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of lipid research","raw_type":"Journal Article"},{"id":"pmh:oai:doaj.org/article:cfe1120f1621497f81b64ea4ca466575","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/cfe1120f1621497f81b64ea4ca466575","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Journal of Lipid Research, Vol 52, Iss 2, Pp 354-360 (2011)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.1194/jlr.p007476","doi":"https://doi.org/10.1194/jlr.p007476","is_oa":true,"landing_page_url":"https://doi.org/10.1194/jlr.p007476","pdf_url":null,"source":{"id":"https://openalex.org/S11400418","display_name":"Journal of Lipid Research","issn_l":"0022-2275","issn":["0022-2275","1539-7262"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-140","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Lipid Research","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":1.0}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[{"id":"https://openalex.org/G3862351915","display_name":"Chronic Intermittent Ethanol and Kv4.2 Channels","funder_award_id":"R01AA022701","funder_id":"https://openalex.org/F4320337330","funder_display_name":"National Institute on Alcohol Abuse and Alcoholism"}],"funders":[{"id":"https://openalex.org/F4320337330","display_name":"National Institute on Alcohol Abuse and Alcoholism","ror":"https://ror.org/02jzrsm59"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":31,"referenced_works":["https://openalex.org/W99741135","https://openalex.org/W1513833217","https://openalex.org/W2030447006","https://openalex.org/W2037252383","https://openalex.org/W2040433877","https://openalex.org/W2048755332","https://openalex.org/W2060090217","https://openalex.org/W2068700927","https://openalex.org/W2071759640","https://openalex.org/W2079083209","https://openalex.org/W2095446066","https://openalex.org/W2101736118","https://openalex.org/W2103484632","https://openalex.org/W2105281057","https://openalex.org/W2106343349","https://openalex.org/W2107707255","https://openalex.org/W2140079333","https://openalex.org/W2140609764","https://openalex.org/W2142642125","https://openalex.org/W2142769596","https://openalex.org/W2149813409","https://openalex.org/W2151722413","https://openalex.org/W2161527180","https://openalex.org/W2256068727","https://openalex.org/W2311018354","https://openalex.org/W2394084479","https://openalex.org/W2407327644","https://openalex.org/W2477872031","https://openalex.org/W4230870013","https://openalex.org/W4285719527","https://openalex.org/W4292000718"],"related_works":["https://openalex.org/W1988536216","https://openalex.org/W2779546624","https://openalex.org/W1965912762","https://openalex.org/W2104177528","https://openalex.org/W2167377151","https://openalex.org/W1966379363","https://openalex.org/W2023295254","https://openalex.org/W7100922433","https://openalex.org/W7099408057","https://openalex.org/W2955546501"],"abstract_inverted_index":{"A":[0],"number":[1],"of":[2,14,72],"recent":[3],"genome-wide":[4],"association":[5,116,151,185,208,243],"(GWA)":[6],"studies":[7,35],"have":[8],"identified":[9,31],"several":[10],"novel":[11],"genetic":[12],"determinants":[13],"plasma":[15],"lipid":[16,42,255],"and":[17,43,68,87,105,140,174,197,211,232,257],"lipoprotein":[18,44],"concentrations":[19,45],"in":[20,32,46,56,59,270,277],"European":[21],"populations.":[22],"However,":[23],"it":[24],"is":[25],"still":[26],"unclear":[27],"whether":[28],"these":[29,73],"loci":[30,58],"Caucasian":[33],"GWA":[34],"also":[36,273],"exert":[37],"the":[38,70,263],"same":[39],"effect":[40],"on":[41,254],"a":[47,60,275,278],"Chinese":[48,61,279],"population.":[49,281],"We":[50],"genotyped":[51],"10":[52],"single-nucleotide":[53],"polymorphisms":[54],"(SNPs)":[55],"nine":[57],"Han":[62,280],"population":[63],"sample":[64],"(n":[65],"=":[66],"4,192)":[67],"assessed":[69],"associations":[71],"SNPs":[74,249],"with":[75,117,152,186,209,244,267],"metabolic":[76,268],"traits,":[77],"using":[78],"linear":[79],"regression":[80],"adjusted":[81],"for":[82,115,150,184,207,242],"age,":[83],"gender,":[84],"diabetes":[85],"status,":[86],"body":[88],"mass":[89],"index.":[90],"Three":[91],"variants":[92,121,155,190,213,264],"(rs12654264,":[93,191],"P":[94,100,107,123,129,135,142,157,163,169,176,192,199,215,221,227,234],"\u223c":[95,101,108,124,130,136,143,158,164,170,177,193,200,216,222,228,235],"1.7":[96],"\u00d7":[97,103,110,126,132,138,145,160,166,172,179,195,202,218,224,230,237],"10(-6);":[98,139],"rs3764261,":[99,175,226],"7.1":[102],"10(-7);":[104,133,173],"rs4420638,":[106,198,233],"1.1":[109],"10(-3))":[111],"showed":[112,147,181,204,239],"strong":[113,148,182,205,240,251],"evidence":[114,149,183,206,241],"total":[118,245],"cholesterol;":[119],"four":[120,154,212],"(rs780094,":[122],"1.8":[125],"10(-11);":[127],"rs17145738,":[128],"5.0":[131],"rs326,":[134,162],"2.3":[137,194],"rs439401,":[141],"2.2":[144],"10(-5))":[146,238],"triglycerides,":[153],"(rs17145738,":[156],"1.9":[159],"10(-4);":[161,167,225],"9.7":[165],"rs1800588,":[168,220],"1.5":[171],"4.3":[178],"10(-14))":[180],"HDL-cholesterol":[187],"(HDL-C),":[188],"two":[189],"10(-5);":[196],"3.6":[201],"10(-4))":[203],"LDL-C,":[210],"(rs326,":[214],"2.8":[217],"10(-3);":[219,231],"6.1":[223],"2.0":[229],"9.4":[236],"cholesterol-HDL-C-related":[246],"ratio.":[247],"These":[248],"generated":[250],"combined":[252],"effects":[253],"traits":[256,269],"dyslipidemia.":[258],"Our":[259],"findings":[260],"indicate":[261],"that":[262,265],"associated":[266],"Europeans":[271],"may":[272],"play":[274],"role":[276]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":3},{"year":2023,"cited_by_count":3},{"year":2022,"cited_by_count":2},{"year":2021,"cited_by_count":3},{"year":2020,"cited_by_count":5},{"year":2019,"cited_by_count":5},{"year":2017,"cited_by_count":6},{"year":2016,"cited_by_count":3},{"year":2015,"cited_by_count":9},{"year":2014,"cited_by_count":4},{"year":2013,"cited_by_count":4},{"year":2012,"cited_by_count":2}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2016-06-24T00:00:00"}