{"id":"https://openalex.org/W2131910367","doi":"https://doi.org/10.1093/jee/98.1.18","title":"Pest Control by Genetic Manipulation of Sex Ratio","display_name":"Pest Control by Genetic Manipulation of Sex Ratio","publication_year":2005,"publication_date":"2005-02-01","ids":{"openalex":"https://openalex.org/W2131910367","doi":"https://doi.org/10.1093/jee/98.1.18","mag":"2131910367","pmid":"https://pubmed.ncbi.nlm.nih.gov/15765662"},"language":"en","primary_location":{"id":"doi:10.1093/jee/98.1.18","doi":"https://doi.org/10.1093/jee/98.1.18","is_oa":false,"landing_page_url":"https://doi.org/10.1093/jee/98.1.18","pdf_url":null,"source":{"id":"https://openalex.org/S146976949","display_name":"Journal of Economic Entomology","issn_l":"0022-0493","issn":["0022-0493","1938-291X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-d","jufo-1","medline","norway-1","poland-70","russia-white-list-1"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Economic Entomology","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5002450920","display_name":"Paul Schliekelman","orcid":"https://orcid.org/0000-0001-7967-3520","observed_orcids":["https://orcid.org/0000-0001-7967-3520"]},"institutions":[{"id":"https://openalex.org/I165733156","display_name":"University of Georgia","ror":"https://ror.org/00te3t702","country_code":"US","type":"education","lineage":["https://openalex.org/I165733156"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Paul Schliekelman","raw_affiliation_strings":["Department of Statistics, University of Georgia, Athens, GA 30602-1952, USA","Department of Statistics, University of Georgia, Athens, GA 30602\u20101952"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Statistics, University of Georgia, Athens, GA 30602-1952, USA","institution_ids":["https://openalex.org/I165733156"]},{"raw_affiliation_string":"Department of Statistics, University of Georgia, Athens, GA 30602\u20101952","institution_ids":["https://openalex.org/I165733156"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5018915016","display_name":"Stephen P. Ellner","orcid":"https://orcid.org/0000-0002-8351-9734","observed_orcids":["https://orcid.org/0000-0002-8351-9734"]},"institutions":[{"id":"https://openalex.org/I205783295","display_name":"Cornell University","ror":"https://ror.org/05bnh6r87","country_code":"US","type":"education","lineage":["https://openalex.org/I205783295"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Stephen Ellner","raw_affiliation_strings":["Department of Ecology and Evolutionary Biology, Cornell University, Ithaca, NY 14853\u20132701"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Ecology and Evolutionary Biology, Cornell University, Ithaca, NY 14853\u20132701","institution_ids":["https://openalex.org/I205783295"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5042313556","display_name":"Fred L. Gould","orcid":"https://orcid.org/0000-0001-8597-5306","observed_orcids":["https://orcid.org/0000-0001-8597-5306"]},"institutions":[{"id":"https://openalex.org/I137902535","display_name":"North Carolina State University","ror":"https://ror.org/04tj63d06","country_code":"US","type":"education","lineage":["https://openalex.org/I137902535"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Fred Gould","raw_affiliation_strings":["Department of Entomology, North Carolina State University, Raleigh, NC 27695\u20137634"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Entomology, North Carolina State University, Raleigh, NC 27695\u20137634","institution_ids":["https://openalex.org/I137902535"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5018915016"],"corresponding_institution_ids":["https://openalex.org/I205783295"],"apc_list":{"value":4328,"currency":"USD","value_usd":4328},"apc_paid":null,"fwci":1.2434,"has_fulltext":false,"cited_by_count":89,"citation_normalized_percentile":{"value":0.78926606,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":94,"max":100},"biblio":{"volume":"98","issue":"1","first_page":"18","last_page":"34"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12043","display_name":"Insect behavior and control techniques","score":0.9336000084877014,"subfield":{"id":"https://openalex.org/subfields/1109","display_name":"Insect Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T12043","display_name":"Insect behavior and control techniques","score":0.9336000084877014,"subfield":{"id":"https://openalex.org/subfields/1109","display_name":"Insect Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10482","display_name":"Mathematical and Theoretical Epidemiology and Ecology Models","score":0.05550000071525574,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12701","display_name":"Biological Control of Invasive Species","score":0.002199999988079071,"subfield":{"id":"https://openalex.org/subfields/1109","display_name":"Insect Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/sex-ratio-manipulation","display_name":"sex ratio manipulation","score":0.8690000176429749},{"id":"https://openalex.org/keywords/pest-management","display_name":"pest control","score":0.7099999785423279},{"id":"https://openalex.org/keywords/sterile-insect-technique","display_name":"sterile insect technique","score":0.8420000076293945},{"id":"https://openalex.org/keywords/population-suppression","display_name":"population suppression","score":0.5239999890327454},{"id":"https://openalex.org/keywords/release-size","display_name":"release size","score":0.43799999356269836},{"id":"https://openalex.org/keywords/genetic-load","display_name":"genetic load","score":0.5350000262260437},{"id":"https://openalex.org/keywords/insect-population-dynamics","display_name":"insect population dynamics","score":0.5109999775886536}],"concepts":[{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.95623779296875},{"id":"https://openalex.org/C22508944","wikidata":"https://www.wikidata.org/wiki/Q568174","display_name":"PEST analysis","level":2,"score":0.7309274673461914},{"id":"https://openalex.org/C57520943","wikidata":"https://www.wikidata.org/wiki/Q1068155","display_name":"Sex ratio","level":3,"score":0.5872077345848083},{"id":"https://openalex.org/C540442320","wikidata":"https://www.wikidata.org/wiki/Q2306047","display_name":"Pest control","level":2,"score":0.579596757888794},{"id":"https://openalex.org/C150903083","wikidata":"https://www.wikidata.org/wiki/Q7108","display_name":"Biotechnology","level":1,"score":0.32774144411087036},{"id":"https://openalex.org/C6557445","wikidata":"https://www.wikidata.org/wiki/Q173113","display_name":"Agronomy","level":1,"score":0.2808890640735626},{"id":"https://openalex.org/C59822182","wikidata":"https://www.wikidata.org/wiki/Q441","display_name":"Botany","level":1,"score":0.19691726565361023},{"id":"https://openalex.org/C149923435","wikidata":"https://www.wikidata.org/wiki/Q37732","display_name":"Demography","level":1,"score":0.08707094192504883},{"id":"https://openalex.org/C2908647359","wikidata":"https://www.wikidata.org/wiki/Q2625603","display_name":"Population","level":2,"score":0.06438758969306946},{"id":"https://openalex.org/C144024400","wikidata":"https://www.wikidata.org/wiki/Q21201","display_name":"Sociology","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D000483","descriptor_name":"Alleles","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005298","descriptor_name":"Fertility","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D005818","descriptor_name":"Genetic Engineering","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D007313","descriptor_name":"Insecta","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010572","descriptor_name":"Pest Control, Biological","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D011156","descriptor_name":"Population Density","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012744","descriptor_name":"Sex Ratio","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D014998","descriptor_name":"Y Chromosome","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.1093/jee/98.1.18","doi":"https://doi.org/10.1093/jee/98.1.18","is_oa":false,"landing_page_url":"https://doi.org/10.1093/jee/98.1.18","pdf_url":null,"source":{"id":"https://openalex.org/S146976949","display_name":"Journal of Economic Entomology","issn_l":"0022-0493","issn":["0022-0493","1938-291X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-d","jufo-1","medline","norway-1","poland-70","russia-white-list-1"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Economic Entomology","raw_type":"journal-article"},{"id":"doi:10.1603/0022-0493-98.1.18","doi":"https://doi.org/10.1603/0022-0493-98.1.18","is_oa":false,"landing_page_url":"https://doi.org/10.1603/0022-0493-98.1.18","pdf_url":null,"source":{"id":"https://openalex.org/S146976949","display_name":"Journal of Economic Entomology","issn_l":"0022-0493","issn":["0022-0493","1938-291X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-d","jufo-1","medline","norway-1","poland-70","russia-white-list-1"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Economic Entomology","raw_type":"journal-article"},{"id":"pmid:15765662","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/15765662","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of economic entomology","raw_type":"Journal Article"},{"id":"pmh:10.1603/0022-0493-98.1.18","doi":null,"is_oa":false,"landing_page_url":"http://www.bioone.org/doi/10.1603/0022-0493-98.1.18","pdf_url":null,"source":{"id":"https://openalex.org/S4306402358","display_name":"BioOne Complete (BioOne)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4210111627","host_organization_name":"BioOne","host_organization_lineage":["https://openalex.org/I4210111627"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"text"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Life on land","score":0.4390000104904175,"id":"https://metadata.un.org/sdg/15"},{"display_name":"Zero hunger","score":0.40450000762939453,"id":"https://metadata.un.org/sdg/2"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G3402360465","display_name":null,"funder_award_id":"1 R01 AI54954-01A2","funder_id":"https://openalex.org/F4320337355","funder_display_name":"National Institute of Allergy and Infectious Diseases"},{"id":"https://openalex.org/G3456304329","display_name":"Population genetics of transgenes in mosquito vectors","funder_award_id":"R01AI054954","funder_id":"https://openalex.org/F4320337355","funder_display_name":"National Institute of Allergy and Infectious Diseases"}],"funders":[{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337355","display_name":"National Institute of Allergy and Infectious Diseases","ror":"https://ror.org/043z4tv69"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":20,"referenced_works":["https://openalex.org/W1868621362","https://openalex.org/W1877460931","https://openalex.org/W1972014014","https://openalex.org/W1978958925","https://openalex.org/W1990523373","https://openalex.org/W2034114815","https://openalex.org/W2048320767","https://openalex.org/W2054841553","https://openalex.org/W2069292027","https://openalex.org/W2074767424","https://openalex.org/W2081185991","https://openalex.org/W2090429649","https://openalex.org/W2096048193","https://openalex.org/W2107120675","https://openalex.org/W2135087134","https://openalex.org/W2136857273","https://openalex.org/W2138422382","https://openalex.org/W2140282079","https://openalex.org/W2144959732","https://openalex.org/W2166446824"],"related_works":["https://openalex.org/W2166446824","https://openalex.org/W2132149134","https://openalex.org/W3195465850","https://openalex.org/W2221752443","https://openalex.org/W2179699684","https://openalex.org/W4245727887","https://openalex.org/W2323486393","https://openalex.org/W2320424067","https://openalex.org/W2096048193","https://openalex.org/W2121729641"],"abstract_inverted_index":{"We":[0,20,155,232,293],"model":[1,21],"the":[2,29,45,63,72,77,104,118,128,134,136,139,142,206,212,224,247,264,268,296],"release":[3,187,220,277],"of":[4,18,42,62,103,120,130,138,149,166,177,179,211,228,259,278,299],"insects":[5,191],"carrying":[6,44,57,98],"an":[7,315],"allele":[8,65,79,106,203,303],"at":[9,58,99,162],"multiple":[10],"loci":[11,131],"that":[12,54,95,157,312],"shifts":[13],"sex":[14,25,81,151,237],"ratios":[15],"in":[16,40,127,133,175],"favor":[17,41],"males.":[19],"two":[22,189,236],"approaches":[23,111,240],"to":[24,88,209,226,241,305],"ratio":[26,82,152,238],"alteration.":[27],"In":[28,71,261],"first":[30],"(denoted":[31,75],"SD),":[32],"meiotic":[33],"segregation":[34],"(or":[35],"sperm":[36],"fertility)":[37],"is":[38,52,93,107,267,314],"distorted":[39],"gametes":[43],"male-determining":[46],"genetic":[47,317],"element":[48],"(e.g.,":[49],"Y-chromosome).":[50],"It":[51,92],"assumed":[53,94],"any":[55,96],"male":[56,69,172,249],"least":[59,100,163],"one":[60,101],"copy":[61,102],"SD":[64,186,265,300],"produces":[66],"only":[67,222],"genotypically":[68],"offspring.":[70],"second":[73],"approach":[74,266],"PM),":[76],"inserted":[78,202],"alters":[80],"by":[83,116,147,276],"causing":[84],"genetically":[85],"female":[86],"individuals":[87],"become":[89],"phenotypically":[90,108],"male.":[91,109],"insect":[97,195],"PM":[105,302],"Both":[110],"reduce":[112,205,223],"future":[113],"population":[114,208,214,225],"growth":[115],"reducing":[117],"number":[119,129,258,298],"phenotypic":[121],"females.":[122],"The":[123],"models":[124],"allow":[125],"variation":[126],"used":[132,307],"release,":[135,140],"size":[137],"and":[141,196,246,286,301],"negative":[143],"fitness":[144,199],"effect":[145],"caused":[146],"insertion":[148],"each":[150,321],"altering":[153],"allele.":[154],"show":[156],"such":[158],"releases":[159,173,255],"may":[160],"be":[161,306],"2":[164],"orders":[165],"magnitude":[167],"more":[168],"effective":[169],"than":[170],"sterile":[171,248],"(SIT)":[174],"terms":[176],"numbers":[178],"surviving":[180],"insects.":[181],"For":[182],"example,":[183],"a":[184,197,217,242,257],"single":[185],"with":[188,271],"released":[190],"for":[192,320],"every":[193],"wild":[194],"5%":[198],"cost":[200],"per":[201],"could":[204],"target":[207],"1/1000th":[210],"no-release":[213],"size,":[215],"whereas":[216],"similar-sized":[218],"SIT":[219,288],"would":[221],"one-fifth":[227],"its":[229],"original":[230],"size.":[231],"also":[233,294],"compare":[234],"these":[235,262],"alteration":[239],"female-killing":[243],"(FK)":[244],"system":[245],"technique":[250],"when":[251],"there":[252,313],"are":[253],"repeated":[254],"over":[256],"generations.":[260],"comparisons,":[263],"most":[269],"efficient":[270],"equivalent":[272],"pest":[273],"suppression":[274],"achieved":[275],"approximately":[279],"1":[280],"SD,":[281],"1.5-20":[282],"PM,":[283],"2-70":[284],"FK,":[285],"16-3,000":[287],"insects,":[289],"depending":[290],"on":[291],"conditions.":[292],"calculate":[295],"optimal":[297],"insertions":[304],"under":[308],"various":[309],"conditions,":[310],"assuming":[311],"additional":[316],"load":[318],"incurred":[319],"allelic":[322],"insertion.":[323]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":18},{"year":2024,"cited_by_count":3},{"year":2023,"cited_by_count":6},{"year":2022,"cited_by_count":7},{"year":2021,"cited_by_count":8},{"year":2020,"cited_by_count":7},{"year":2019,"cited_by_count":3},{"year":2018,"cited_by_count":7},{"year":2017,"cited_by_count":4},{"year":2016,"cited_by_count":3},{"year":2015,"cited_by_count":2},{"year":2014,"cited_by_count":6},{"year":2013,"cited_by_count":4},{"year":2012,"cited_by_count":3}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}