{"id":"https://openalex.org/W2130935482","doi":"https://doi.org/10.1126/science.280.5368.1378","title":"Signals That Regulate Food Intake and Energy Homeostasis","display_name":"Signals That Regulate Food Intake and Energy Homeostasis","publication_year":1998,"publication_date":"1998-05-29","ids":{"openalex":"https://openalex.org/W2130935482","doi":"https://doi.org/10.1126/science.280.5368.1378","mag":"2130935482","pmid":"https://pubmed.ncbi.nlm.nih.gov/9603721"},"language":"en","primary_location":{"id":"doi:10.1126/science.280.5368.1378","doi":"https://doi.org/10.1126/science.280.5368.1378","is_oa":false,"landing_page_url":"https://doi.org/10.1126/science.280.5368.1378","pdf_url":null,"source":{"id":"https://openalex.org/S3880285","display_name":"Science","issn_l":"0036-8075","issn":["0036-8075","0193-4511","1095-9203"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-a","doyens","erih-plus","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315823","host_organization_name":"American Association for the Advancement of Science","host_organization_lineage":["https://openalex.org/P4310315823"],"host_organization_lineage_names":["American Association for the Advancement of Science"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Science","raw_type":"journal-article"},"volume":null,"type":"review","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5072321501","display_name":"Stephen C. Woods","orcid":"https://orcid.org/0000-0002-9130-4098","observed_orcids":["https://orcid.org/0000-0002-9130-4098"]},"institutions":[{"id":"https://openalex.org/I201448701","display_name":"University of Washington","ror":"https://ror.org/00cvxb145","country_code":"US","type":"education","lineage":["https://openalex.org/I201448701"]},{"id":"https://openalex.org/I4210094549","display_name":"VA Puget Sound Health Care System","ror":"https://ror.org/00ky3az31","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1322918889","https://openalex.org/I2799886695","https://openalex.org/I4210094549","https://openalex.org/I4210138024"]},{"id":"https://openalex.org/I4405285767","display_name":"Veterans Administration","ror":"https://ror.org/006ym5897","country_code":"US","type":"government","lineage":["https://openalex.org/I1322918889","https://openalex.org/I4405285767"]},{"id":"https://openalex.org/I92156820","display_name":"University of Cincinnati Medical Center","ror":"https://ror.org/02p72h367","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I92156820"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Stephen C. Woods","raw_affiliation_strings":["S. C. Woods and R. J. Seeley are in the Department of Psychiatry, University of Cincinnati Medical Center, Post Office Box 670559, Cincinnati, OH 45267\u20130559, USA. D. Porte Jr. and M. W. Schwartz are in the Department of Medicine, University of Washington and Veterans Administration Puget Sound Health Care System, Seattle, WA 98108, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"S. C. Woods and R. J. Seeley are in the Department of Psychiatry, University of Cincinnati Medical Center, Post Office Box 670559, Cincinnati, OH 45267\u20130559, USA. D. Porte Jr. and M. W. Schwartz are in the Department of Medicine, University of Washington and Veterans Administration Puget Sound Health Care System, Seattle, WA 98108, USA","institution_ids":["https://openalex.org/I201448701","https://openalex.org/I4210094549","https://openalex.org/I4405285767","https://openalex.org/I92156820"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5065488328","display_name":"Randy J. Seeley","orcid":"https://orcid.org/0000-0002-3721-5625","observed_orcids":["https://orcid.org/0000-0002-3721-5625"]},"institutions":[{"id":"https://openalex.org/I201448701","display_name":"University of Washington","ror":"https://ror.org/00cvxb145","country_code":"US","type":"education","lineage":["https://openalex.org/I201448701"]},{"id":"https://openalex.org/I4210094549","display_name":"VA Puget Sound Health Care System","ror":"https://ror.org/00ky3az31","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1322918889","https://openalex.org/I2799886695","https://openalex.org/I4210094549","https://openalex.org/I4210138024"]},{"id":"https://openalex.org/I4405285767","display_name":"Veterans Administration","ror":"https://ror.org/006ym5897","country_code":"US","type":"government","lineage":["https://openalex.org/I1322918889","https://openalex.org/I4405285767"]},{"id":"https://openalex.org/I92156820","display_name":"University of Cincinnati Medical Center","ror":"https://ror.org/02p72h367","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I92156820"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Randy J. Seeley","raw_affiliation_strings":["S. C. Woods and R. J. Seeley are in the Department of Psychiatry, University of Cincinnati Medical Center, Post Office Box 670559, Cincinnati, OH 45267\u20130559, USA. D. Porte Jr. and M. W. Schwartz are in the Department of Medicine, University of Washington and Veterans Administration Puget Sound Health Care System, Seattle, WA 98108, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"S. C. Woods and R. J. Seeley are in the Department of Psychiatry, University of Cincinnati Medical Center, Post Office Box 670559, Cincinnati, OH 45267\u20130559, USA. D. Porte Jr. and M. W. Schwartz are in the Department of Medicine, University of Washington and Veterans Administration Puget Sound Health Care System, Seattle, WA 98108, USA","institution_ids":["https://openalex.org/I201448701","https://openalex.org/I4210094549","https://openalex.org/I4405285767","https://openalex.org/I92156820"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5108238933","display_name":"Daniel Porte","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I201448701","display_name":"University of Washington","ror":"https://ror.org/00cvxb145","country_code":"US","type":"education","lineage":["https://openalex.org/I201448701"]},{"id":"https://openalex.org/I4210094549","display_name":"VA Puget Sound Health Care System","ror":"https://ror.org/00ky3az31","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1322918889","https://openalex.org/I2799886695","https://openalex.org/I4210094549","https://openalex.org/I4210138024"]},{"id":"https://openalex.org/I4405285767","display_name":"Veterans Administration","ror":"https://ror.org/006ym5897","country_code":"US","type":"government","lineage":["https://openalex.org/I1322918889","https://openalex.org/I4405285767"]},{"id":"https://openalex.org/I92156820","display_name":"University of Cincinnati Medical Center","ror":"https://ror.org/02p72h367","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I92156820"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Daniel Porte","raw_affiliation_strings":["S. C. Woods and R. J. Seeley are in the Department of Psychiatry, University of Cincinnati Medical Center, Post Office Box 670559, Cincinnati, OH 45267\u20130559, USA. D. Porte Jr. and M. W. Schwartz are in the Department of Medicine, University of Washington and Veterans Administration Puget Sound Health Care System, Seattle, WA 98108, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"S. C. Woods and R. J. Seeley are in the Department of Psychiatry, University of Cincinnati Medical Center, Post Office Box 670559, Cincinnati, OH 45267\u20130559, USA. D. Porte Jr. and M. W. Schwartz are in the Department of Medicine, University of Washington and Veterans Administration Puget Sound Health Care System, Seattle, WA 98108, USA","institution_ids":["https://openalex.org/I201448701","https://openalex.org/I4210094549","https://openalex.org/I4405285767","https://openalex.org/I92156820"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5053926256","display_name":"Michael W. Schwartz","orcid":"https://orcid.org/0000-0003-1619-0331","observed_orcids":["https://orcid.org/0000-0003-1619-0331"]},"institutions":[{"id":"https://openalex.org/I201448701","display_name":"University of Washington","ror":"https://ror.org/00cvxb145","country_code":"US","type":"education","lineage":["https://openalex.org/I201448701"]},{"id":"https://openalex.org/I4210094549","display_name":"VA Puget Sound Health Care System","ror":"https://ror.org/00ky3az31","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1322918889","https://openalex.org/I2799886695","https://openalex.org/I4210094549","https://openalex.org/I4210138024"]},{"id":"https://openalex.org/I4405285767","display_name":"Veterans Administration","ror":"https://ror.org/006ym5897","country_code":"US","type":"government","lineage":["https://openalex.org/I1322918889","https://openalex.org/I4405285767"]},{"id":"https://openalex.org/I92156820","display_name":"University of Cincinnati Medical Center","ror":"https://ror.org/02p72h367","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I92156820"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Michael W. Schwartz","raw_affiliation_strings":["S. C. Woods and R. J. Seeley are in the Department of Psychiatry, University of Cincinnati Medical Center, Post Office Box 670559, Cincinnati, OH 45267\u20130559, USA. D. Porte Jr. and M. W. Schwartz are in the Department of Medicine, University of Washington and Veterans Administration Puget Sound Health Care System, Seattle, WA 98108, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"S. C. Woods and R. J. Seeley are in the Department of Psychiatry, University of Cincinnati Medical Center, Post Office Box 670559, Cincinnati, OH 45267\u20130559, USA. D. Porte Jr. and M. W. Schwartz are in the Department of Medicine, University of Washington and Veterans Administration Puget Sound Health Care System, Seattle, WA 98108, USA","institution_ids":["https://openalex.org/I201448701","https://openalex.org/I4210094549","https://openalex.org/I4405285767","https://openalex.org/I92156820"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5072321501"],"corresponding_institution_ids":["https://openalex.org/I201448701","https://openalex.org/I4210094549","https://openalex.org/I4405285767","https://openalex.org/I92156820"],"apc_list":null,"apc_paid":null,"fwci":10.6222,"has_fulltext":false,"cited_by_count":1156,"citation_normalized_percentile":{"value":0.99264706,"is_in_top_1_percent":true,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":98,"max":100},"biblio":{"volume":"280","issue":"5368","first_page":"1378","last_page":"1383"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10489","display_name":"Regulation of Appetite and Obesity","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2807","display_name":"Endocrine and Autonomic Systems"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10489","display_name":"Regulation of Appetite and Obesity","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2807","display_name":"Endocrine and Autonomic Systems"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10528","display_name":"Adipokines, Inflammation, and Metabolic Diseases","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11457","display_name":"Adipose Tissue and Metabolism","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/food-intake-regulation","display_name":"food intake regulation","score":0.8100000023841858},{"id":"https://openalex.org/keywords/energy-homeostasis","display_name":"energy homeostasis","score":0.9629999995231628},{"id":"https://openalex.org/keywords/feeding-behavior","display_name":"feeding behavior","score":0.996999979019165},{"id":"https://openalex.org/keywords/molecular-signals","display_name":"molecular signals","score":0.5619999766349792},{"id":"https://openalex.org/keywords/energy-balance","display_name":"energy balance","score":0.7480000257492065},{"id":"https://openalex.org/keywords/adipose-tissue","display_name":"adipose tissue","score":0.9330000281333923},{"id":"https://openalex.org/keywords/energy-expenditure","display_name":"energy expenditure","score":0.7929999828338623}],"concepts":[{"id":"https://openalex.org/C63645605","wikidata":"https://www.wikidata.org/wiki/Q103191","display_name":"Homeostasis","level":2,"score":0.6996577978134155},{"id":"https://openalex.org/C2491326","wikidata":"https://www.wikidata.org/wiki/Q5377024","display_name":"Energy homeostasis","level":3,"score":0.6668657064437866},{"id":"https://openalex.org/C14522933","wikidata":"https://www.wikidata.org/wiki/Q531507","display_name":"Micronutrient","level":2,"score":0.6647851467132568},{"id":"https://openalex.org/C171089720","wikidata":"https://www.wikidata.org/wiki/Q193583","display_name":"Adipose tissue","level":2,"score":0.5265576839447021},{"id":"https://openalex.org/C31903555","wikidata":"https://www.wikidata.org/wiki/Q1637030","display_name":"Food science","level":1,"score":0.4618038535118103},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.4608023166656494},{"id":"https://openalex.org/C3018685816","wikidata":"https://www.wikidata.org/wiki/Q213449","display_name":"Food intake","level":2,"score":0.4585205912590027},{"id":"https://openalex.org/C98045186","wikidata":"https://www.wikidata.org/wiki/Q205663","display_name":"Process (computing)","level":2,"score":0.4359101951122284},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.37984490394592285},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.28096017241477966},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.26785117387771606},{"id":"https://openalex.org/C511355011","wikidata":"https://www.wikidata.org/wiki/Q12174","display_name":"Obesity","level":2,"score":0.0993165373802185},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.0968494713306427},{"id":"https://openalex.org/C111919701","wikidata":"https://www.wikidata.org/wiki/Q9135","display_name":"Operating system","level":1,"score":0.0},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000273","descriptor_name":"Adipose Tissue","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001835","descriptor_name":"Body Weight","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001921","descriptor_name":"Brain","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D004435","descriptor_name":"Eating","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D004734","descriptor_name":"Energy Metabolism","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D006706","descriptor_name":"Homeostasis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006728","descriptor_name":"Hormones","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009479","descriptor_name":"Neuropeptides","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D012527","descriptor_name":"Satiation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1126/science.280.5368.1378","doi":"https://doi.org/10.1126/science.280.5368.1378","is_oa":false,"landing_page_url":"https://doi.org/10.1126/science.280.5368.1378","pdf_url":null,"source":{"id":"https://openalex.org/S3880285","display_name":"Science","issn_l":"0036-8075","issn":["0036-8075","0193-4511","1095-9203"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-a","doyens","erih-plus","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315823","host_organization_name":"American Association for the Advancement of Science","host_organization_lineage":["https://openalex.org/P4310315823"],"host_organization_lineage_names":["American Association for the Advancement of Science"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Science","raw_type":"journal-article"},{"id":"pmid:9603721","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/9603721","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Science (New York, N.Y.)","raw_type":"Journal Article"},{"id":"pmh:oai:CiteSeerX.psu:10.1.1.976.3835","doi":null,"is_oa":false,"landing_page_url":"http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.976.3835","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"http://science.sciencemag.org/content/sci/280/5368/1378.full.pdf","raw_type":"text"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Zero hunger","score":0.5666999816894531,"id":"https://metadata.un.org/sdg/2"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G2107271777","display_name":null,"funder_award_id":"DK17844","funder_id":"https://openalex.org/F4320337357","funder_display_name":"National Institute of Diabetes and Digestive and Kidney Diseases"},{"id":"https://openalex.org/G3879201312","display_name":"Regulatory Responses to Positive Energy Balance","funder_award_id":"R01DK054080","funder_id":"https://openalex.org/F4320337357","funder_display_name":"National Institute of Diabetes and Digestive and Kidney Diseases"},{"id":"https://openalex.org/G4763379275","display_name":"CNS GLP-1 signaling in energy and glucose homeostasis","funder_award_id":"R01DK054890","funder_id":"https://openalex.org/F4320337357","funder_display_name":"National Institute of Diabetes and Digestive and Kidney Diseases"}],"funders":[{"id":"https://openalex.org/F4320337357","display_name":"National Institute of Diabetes and Digestive and Kidney Diseases","ror":"https://ror.org/00adh9b73"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":61,"referenced_works":["https://openalex.org/W238463063","https://openalex.org/W1485094869","https://openalex.org/W1963587096","https://openalex.org/W1964889875","https://openalex.org/W1969964748","https://openalex.org/W1971357456","https://openalex.org/W1982567180","https://openalex.org/W1994091958","https://openalex.org/W1996546748","https://openalex.org/W1996713062","https://openalex.org/W2001214139","https://openalex.org/W2002606463","https://openalex.org/W2010142606","https://openalex.org/W2010342389","https://openalex.org/W2011823591","https://openalex.org/W2013002120","https://openalex.org/W2015125455","https://openalex.org/W2016994959","https://openalex.org/W2019122671","https://openalex.org/W2020223258","https://openalex.org/W2020971663","https://openalex.org/W2027427622","https://openalex.org/W2027740042","https://openalex.org/W2028654736","https://openalex.org/W2037447899","https://openalex.org/W2037493579","https://openalex.org/W2047700282","https://openalex.org/W2047780911","https://openalex.org/W2060682066","https://openalex.org/W2061340727","https://openalex.org/W2064342369","https://openalex.org/W2067250281","https://openalex.org/W2074886533","https://openalex.org/W2074943883","https://openalex.org/W2075019242","https://openalex.org/W2078850444","https://openalex.org/W2079201209","https://openalex.org/W2081494990","https://openalex.org/W2083338331","https://openalex.org/W2087133453","https://openalex.org/W2087759102","https://openalex.org/W2088620792","https://openalex.org/W2088777766","https://openalex.org/W2091085717","https://openalex.org/W2099542131","https://openalex.org/W2105470099","https://openalex.org/W2106397535","https://openalex.org/W2121089716","https://openalex.org/W2125312207","https://openalex.org/W2128859850","https://openalex.org/W2129015790","https://openalex.org/W2129221666","https://openalex.org/W2133635537","https://openalex.org/W2135456335","https://openalex.org/W2147788805","https://openalex.org/W2154006548","https://openalex.org/W2291368943","https://openalex.org/W2341830035","https://openalex.org/W2461067405","https://openalex.org/W4255653564","https://openalex.org/W4285719527"],"related_works":["https://openalex.org/W2014324257","https://openalex.org/W2085642936","https://openalex.org/W3041020252","https://openalex.org/W1987790573","https://openalex.org/W1854143160","https://openalex.org/W2110744330","https://openalex.org/W24394428","https://openalex.org/W2058012977","https://openalex.org/W2165727832","https://openalex.org/W4247212366"],"abstract_inverted_index":{"Feeding":[0],"behavior":[1,26],"is":[2,27,47],"critical":[3],"for":[4],"survival.":[5],"In":[6],"addition":[7],"to":[8,56],"providing":[9],"all":[10],"of":[11,31,44,60,68],"the":[12,34,42,58,66,75,84],"body's":[13,85],"macronutrients":[14],"(carbohydrates,":[15],"lipids,":[16],"and":[17,19,23,87],"proteins)":[18],"most":[20],"micronutrients":[21],"(minerals":[22],"vitamins),":[24],"feeding":[25],"a":[28],"fundamental":[29],"aspect":[30],"energy":[32,61,69,89],"homeostasis,":[33],"process":[35,55],"by":[36],"which":[37],"body":[38],"fuel":[39],"stored":[40],"in":[41],"form":[43],"adipose":[45],"tissue":[46],"held":[48],"constant":[49],"over":[50],"long":[51],"intervals.":[52],"For":[53],"this":[54],"occur,":[57],"amount":[59,67],"consumed":[62],"must":[63],"match":[64],"precisely":[65],"expended.":[70],"This":[71],"review":[72],"focuses":[73],"on":[74],"molecular":[76],"signals":[77],"that":[78],"modulate":[79],"food":[80],"intake":[81],"while":[82],"integrating":[83],"immediate":[86],"long-term":[88],"needs.":[90]},"counts_by_year":[{"year":2026,"cited_by_count":4},{"year":2025,"cited_by_count":9},{"year":2024,"cited_by_count":11},{"year":2023,"cited_by_count":10},{"year":2022,"cited_by_count":10},{"year":2021,"cited_by_count":20},{"year":2020,"cited_by_count":24},{"year":2019,"cited_by_count":35},{"year":2018,"cited_by_count":30},{"year":2017,"cited_by_count":20},{"year":2016,"cited_by_count":40},{"year":2015,"cited_by_count":23},{"year":2014,"cited_by_count":42},{"year":2013,"cited_by_count":27},{"year":2012,"cited_by_count":52}],"updated_date":"2026-11-06T12:05:46.655746","created_date":"2016-06-24T00:00:00"}