{"id":"https://openalex.org/W2129885366","doi":"https://doi.org/10.1111/j.1462-2920.2009.02138.x","title":"The major outer membrane protein OmpU of Vibrio splendidus contributes to host antimicrobial peptide resistance and is required for virulence in the oyster Crassostrea gigas","display_name":"The major outer membrane protein OmpU of Vibrio splendidus contributes to host antimicrobial peptide resistance and is required for virulence in the oyster Crassostrea gigas","publication_year":2010,"publication_date":"2010-01-13","ids":{"openalex":"https://openalex.org/W2129885366","doi":"https://doi.org/10.1111/j.1462-2920.2009.02138.x","mag":"2129885366","pmid":"https://pubmed.ncbi.nlm.nih.gov/20074236"},"language":"en","primary_location":{"id":"doi:10.1111/j.1462-2920.2009.02138.x","doi":"https://doi.org/10.1111/j.1462-2920.2009.02138.x","is_oa":true,"landing_page_url":"https://doi.org/10.1111/j.1462-2920.2009.02138.x","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/j.1462-2920.2009.02138.x","source":{"id":"https://openalex.org/S6919857","display_name":"Environmental Microbiology","issn_l":"1462-2912","issn":["1462-2912","1462-2920"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Environmental Microbiology","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/j.1462-2920.2009.02138.x","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5079535786","display_name":"Marylise Duperthuy","orcid":"https://orcid.org/0000-0002-9226-9343","observed_orcids":["https://orcid.org/0000-0002-9226-9343"]},"institutions":[{"id":"https://openalex.org/I1294671590","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73","country_code":"FR","type":"government","lineage":["https://openalex.org/I1294671590"]},{"id":"https://openalex.org/I154202486","display_name":"Ifremer","ror":"https://ror.org/044jxhp58","country_code":"FR","type":"facility","lineage":["https://openalex.org/I154202486"]},{"id":"https://openalex.org/I19894307","display_name":"Universit\u00e9 de Montpellier","ror":"https://ror.org/051escj72","country_code":"FR","type":"education","lineage":["https://openalex.org/I19894307"]},{"id":"https://openalex.org/I4387154756","display_name":"Universit\u00e9 Montpellier 2","ror":"https://ror.org/00wh4bp03","country_code":"FR","type":"education","lineage":["https://openalex.org/I19894307","https://openalex.org/I4387154756"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Marylise Duperthuy","raw_affiliation_strings":["CNRS, UMR 5119, Laboratoire Ecosyst\u00e8mes lagunaires, Universit\u00e9 Montpellier 2, 34095 Montpellier, France","Ifremer and","Universit\u00e9 Montpellier 2, Laboratoire 'Ecosyst\u00e8mes lagunaires', 34095 Montpellier, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"CNRS, UMR 5119, Laboratoire Ecosyst\u00e8mes lagunaires, Universit\u00e9 Montpellier 2, 34095 Montpellier, France","institution_ids":["https://openalex.org/I1294671590","https://openalex.org/I19894307","https://openalex.org/I4387154756"]},{"raw_affiliation_string":"Ifremer and","institution_ids":["https://openalex.org/I154202486"]},{"raw_affiliation_string":"Universit\u00e9 Montpellier 2, Laboratoire 'Ecosyst\u00e8mes lagunaires', 34095 Montpellier, France","institution_ids":["https://openalex.org/I4387154756"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5009103985","display_name":"Johan Binesse","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1294671590","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73","country_code":"FR","type":"government","lineage":["https://openalex.org/I1294671590"]},{"id":"https://openalex.org/I157536573","display_name":"Institut Pasteur","ror":"https://ror.org/0495fxg12","country_code":"FR","type":"nonprofit","lineage":["https://openalex.org/I157536573"]},{"id":"https://openalex.org/I4210162100","display_name":"Department of Genomes & Genetics","ror":"https://ror.org/05etkex69","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I157536573","https://openalex.org/I4210096427","https://openalex.org/I4210162100"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Johan Binesse","raw_affiliation_strings":["Institut Pasteur, CNRS, URA 2171, Laboratoire \u2018Plasticite\u0301 du ge\u0301nome bacte\u0301rien\u2019, 75015 Paris, France","Institut Pasteur, CNRS, URA 2171, Laboratoire 'Plasticit\u00e9 du g\u00e9nome bact\u00e9rien', 75015 Paris, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institut Pasteur, CNRS, URA 2171, Laboratoire \u2018Plasticite\u0301 du ge\u0301nome bacte\u0301rien\u2019, 75015 Paris, France","institution_ids":["https://openalex.org/I1294671590","https://openalex.org/I157536573","https://openalex.org/I4210162100"]},{"raw_affiliation_string":"Institut Pasteur, CNRS, URA 2171, Laboratoire 'Plasticit\u00e9 du g\u00e9nome bact\u00e9rien', 75015 Paris, France","institution_ids":["https://openalex.org/I1294671590","https://openalex.org/I157536573","https://openalex.org/I4210162100"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5065558873","display_name":"Fr\u00e9d\u00e9rique Le Roux","orcid":"https://orcid.org/0000-0002-9112-6199","observed_orcids":["https://orcid.org/0000-0002-9112-6199"]},"institutions":[{"id":"https://openalex.org/I1294671590","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73","country_code":"FR","type":"government","lineage":["https://openalex.org/I1294671590"]},{"id":"https://openalex.org/I154202486","display_name":"Ifremer","ror":"https://ror.org/044jxhp58","country_code":"FR","type":"facility","lineage":["https://openalex.org/I154202486"]},{"id":"https://openalex.org/I157536573","display_name":"Institut Pasteur","ror":"https://ror.org/0495fxg12","country_code":"FR","type":"nonprofit","lineage":["https://openalex.org/I157536573"]},{"id":"https://openalex.org/I4210162100","display_name":"Department of Genomes & Genetics","ror":"https://ror.org/05etkex69","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I157536573","https://openalex.org/I4210096427","https://openalex.org/I4210162100"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Fr\u00e9d\u00e9rique Le Roux","raw_affiliation_strings":["Institut Pasteur, CNRS, URA 2171, Laboratoire \u2018Plasticite\u0301 du ge\u0301nome bacte\u0301rien\u2019, 75015 Paris, France","Laboratoire de ge\u0301ne\u0301tique et pathologie, Ifremer, 17390 La Tremblade, France","Institut Pasteur, CNRS, URA 2171, Laboratoire 'Plasticit\u00e9 du g\u00e9nome bact\u00e9rien', 75015 Paris, France","Laboratoire de g\u00e9n\u00e9tique et pathologie, Ifremer, 17390 La Tremblade, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institut Pasteur, CNRS, URA 2171, Laboratoire \u2018Plasticite\u0301 du ge\u0301nome bacte\u0301rien\u2019, 75015 Paris, France","institution_ids":["https://openalex.org/I1294671590","https://openalex.org/I157536573","https://openalex.org/I4210162100"]},{"raw_affiliation_string":"Laboratoire de ge\u0301ne\u0301tique et pathologie, Ifremer, 17390 La Tremblade, France","institution_ids":["https://openalex.org/I154202486"]},{"raw_affiliation_string":"Institut Pasteur, CNRS, URA 2171, Laboratoire 'Plasticit\u00e9 du g\u00e9nome bact\u00e9rien', 75015 Paris, France","institution_ids":["https://openalex.org/I1294671590","https://openalex.org/I157536573","https://openalex.org/I4210162100"]},{"raw_affiliation_string":"Laboratoire de g\u00e9n\u00e9tique et pathologie, Ifremer, 17390 La Tremblade, France","institution_ids":["https://openalex.org/I154202486"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5004488113","display_name":"Bernard Romestand","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1294671590","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73","country_code":"FR","type":"government","lineage":["https://openalex.org/I1294671590"]},{"id":"https://openalex.org/I154202486","display_name":"Ifremer","ror":"https://ror.org/044jxhp58","country_code":"FR","type":"facility","lineage":["https://openalex.org/I154202486"]},{"id":"https://openalex.org/I19894307","display_name":"Universit\u00e9 de Montpellier","ror":"https://ror.org/051escj72","country_code":"FR","type":"education","lineage":["https://openalex.org/I19894307"]},{"id":"https://openalex.org/I4387154756","display_name":"Universit\u00e9 Montpellier 2","ror":"https://ror.org/00wh4bp03","country_code":"FR","type":"education","lineage":["https://openalex.org/I19894307","https://openalex.org/I4387154756"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Bernard Romestand","raw_affiliation_strings":["CNRS, UMR 5119, Laboratoire \u2018Ecosyste\u0300mes lagunaires\u2019, Universite\u0301 Montpellier 2, 34095 Montpellier, France","Ifremer and","Universite\u0301 Montpellier 2, Laboratoire \u2018Ecosyste\u0300mes lagunaires\u2019, 34095 Montpellier, France","CNRS, UMR 5119, Laboratoire 'Ecosyst\u00e8mes lagunaires', Universit\u00e9 Montpellier 2, 34095 Montpellier, France","Universit\u00e9 Montpellier 2, Laboratoire 'Ecosyst\u00e8mes lagunaires', 34095 Montpellier, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"CNRS, UMR 5119, Laboratoire \u2018Ecosyste\u0300mes lagunaires\u2019, Universite\u0301 Montpellier 2, 34095 Montpellier, France","institution_ids":["https://openalex.org/I1294671590","https://openalex.org/I19894307","https://openalex.org/I4387154756"]},{"raw_affiliation_string":"Ifremer and","institution_ids":["https://openalex.org/I154202486"]},{"raw_affiliation_string":"Universite\u0301 Montpellier 2, Laboratoire \u2018Ecosyste\u0300mes lagunaires\u2019, 34095 Montpellier, France","institution_ids":["https://openalex.org/I4387154756"]},{"raw_affiliation_string":"CNRS, UMR 5119, Laboratoire 'Ecosyst\u00e8mes lagunaires', Universit\u00e9 Montpellier 2, 34095 Montpellier, France","institution_ids":["https://openalex.org/I1294671590","https://openalex.org/I19894307","https://openalex.org/I4387154756"]},{"raw_affiliation_string":"Universit\u00e9 Montpellier 2, Laboratoire 'Ecosyst\u00e8mes lagunaires', 34095 Montpellier, France","institution_ids":["https://openalex.org/I4387154756"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5053609508","display_name":"Audrey Caro","orcid":"https://orcid.org/0009-0006-8421-3522","observed_orcids":["https://orcid.org/0009-0006-8421-3522"]},"institutions":[{"id":"https://openalex.org/I1294671590","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73","country_code":"FR","type":"government","lineage":["https://openalex.org/I1294671590"]},{"id":"https://openalex.org/I154202486","display_name":"Ifremer","ror":"https://ror.org/044jxhp58","country_code":"FR","type":"facility","lineage":["https://openalex.org/I154202486"]},{"id":"https://openalex.org/I19894307","display_name":"Universit\u00e9 de Montpellier","ror":"https://ror.org/051escj72","country_code":"FR","type":"education","lineage":["https://openalex.org/I19894307"]},{"id":"https://openalex.org/I4387154756","display_name":"Universit\u00e9 Montpellier 2","ror":"https://ror.org/00wh4bp03","country_code":"FR","type":"education","lineage":["https://openalex.org/I19894307","https://openalex.org/I4387154756"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Audrey Caro","raw_affiliation_strings":["CNRS, UMR 5119, Laboratoire \u2018Ecosyste\u0300mes lagunaires\u2019, Universite\u0301 Montpellier 2, 34095 Montpellier, France","Ifremer and","Universite\u0301 Montpellier 2, Laboratoire \u2018Ecosyste\u0300mes lagunaires\u2019, 34095 Montpellier, France","CNRS, UMR 5119, Laboratoire 'Ecosyst\u00e8mes lagunaires', Universit\u00e9 Montpellier 2, 34095 Montpellier, France","Universit\u00e9 Montpellier 2, Laboratoire 'Ecosyst\u00e8mes lagunaires', 34095 Montpellier, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"CNRS, UMR 5119, Laboratoire \u2018Ecosyste\u0300mes lagunaires\u2019, Universite\u0301 Montpellier 2, 34095 Montpellier, France","institution_ids":["https://openalex.org/I1294671590","https://openalex.org/I19894307","https://openalex.org/I4387154756"]},{"raw_affiliation_string":"Ifremer and","institution_ids":["https://openalex.org/I154202486"]},{"raw_affiliation_string":"Universite\u0301 Montpellier 2, Laboratoire \u2018Ecosyste\u0300mes lagunaires\u2019, 34095 Montpellier, France","institution_ids":["https://openalex.org/I4387154756"]},{"raw_affiliation_string":"CNRS, UMR 5119, Laboratoire 'Ecosyst\u00e8mes lagunaires', Universit\u00e9 Montpellier 2, 34095 Montpellier, France","institution_ids":["https://openalex.org/I1294671590","https://openalex.org/I19894307","https://openalex.org/I4387154756"]},{"raw_affiliation_string":"Universit\u00e9 Montpellier 2, Laboratoire 'Ecosyst\u00e8mes lagunaires', 34095 Montpellier, France","institution_ids":["https://openalex.org/I4387154756"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5043377427","display_name":"Patrice Got","orcid":"https://orcid.org/0000-0001-7528-0770","observed_orcids":["https://orcid.org/0000-0001-7528-0770"]},"institutions":[{"id":"https://openalex.org/I1294671590","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73","country_code":"FR","type":"government","lineage":["https://openalex.org/I1294671590"]},{"id":"https://openalex.org/I154202486","display_name":"Ifremer","ror":"https://ror.org/044jxhp58","country_code":"FR","type":"facility","lineage":["https://openalex.org/I154202486"]},{"id":"https://openalex.org/I19894307","display_name":"Universit\u00e9 de Montpellier","ror":"https://ror.org/051escj72","country_code":"FR","type":"education","lineage":["https://openalex.org/I19894307"]},{"id":"https://openalex.org/I4387154756","display_name":"Universit\u00e9 Montpellier 2","ror":"https://ror.org/00wh4bp03","country_code":"FR","type":"education","lineage":["https://openalex.org/I19894307","https://openalex.org/I4387154756"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Patrice Got","raw_affiliation_strings":["CNRS, UMR 5119, Laboratoire \u2018Ecosyste\u0300mes lagunaires\u2019, Universite\u0301 Montpellier 2, 34095 Montpellier, France","Ifremer and","Universite\u0301 Montpellier 2, Laboratoire \u2018Ecosyste\u0300mes lagunaires\u2019, 34095 Montpellier, France","CNRS, UMR 5119, Laboratoire 'Ecosyst\u00e8mes lagunaires', Universit\u00e9 Montpellier 2, 34095 Montpellier, France","Universit\u00e9 Montpellier 2, Laboratoire 'Ecosyst\u00e8mes lagunaires', 34095 Montpellier, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"CNRS, UMR 5119, Laboratoire \u2018Ecosyste\u0300mes lagunaires\u2019, Universite\u0301 Montpellier 2, 34095 Montpellier, France","institution_ids":["https://openalex.org/I1294671590","https://openalex.org/I19894307","https://openalex.org/I4387154756"]},{"raw_affiliation_string":"Ifremer and","institution_ids":["https://openalex.org/I154202486"]},{"raw_affiliation_string":"Universite\u0301 Montpellier 2, Laboratoire \u2018Ecosyste\u0300mes lagunaires\u2019, 34095 Montpellier, France","institution_ids":["https://openalex.org/I4387154756"]},{"raw_affiliation_string":"CNRS, UMR 5119, Laboratoire 'Ecosyst\u00e8mes lagunaires', Universit\u00e9 Montpellier 2, 34095 Montpellier, France","institution_ids":["https://openalex.org/I1294671590","https://openalex.org/I19894307","https://openalex.org/I4387154756"]},{"raw_affiliation_string":"Universit\u00e9 Montpellier 2, Laboratoire 'Ecosyst\u00e8mes lagunaires', 34095 Montpellier, France","institution_ids":["https://openalex.org/I4387154756"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5033037635","display_name":"Alain Givaudan","orcid":"https://orcid.org/0000-0002-3901-5133","observed_orcids":["https://orcid.org/0000-0002-3901-5133"]},"institutions":[{"id":"https://openalex.org/I1314251682","display_name":"Institut National de la Recherche Agronomique","ror":"https://ror.org/05y503v71","country_code":"MA","type":"facility","lineage":["https://openalex.org/I1314251682"]},{"id":"https://openalex.org/I4387154544","display_name":"Institut National de la Recherche Agronomique","ror":"https://ror.org/01x3gbx83","country_code":"FR","type":"funder","lineage":["https://openalex.org/I4210088668","https://openalex.org/I4387154544"]},{"id":"https://openalex.org/I4387154756","display_name":"Universit\u00e9 Montpellier 2","ror":"https://ror.org/00wh4bp03","country_code":"FR","type":"education","lineage":["https://openalex.org/I19894307","https://openalex.org/I4387154756"]}],"countries":["FR","MA"],"is_corresponding":false,"raw_author_name":"Alain Givaudan","raw_affiliation_strings":["INRA and","Universite\u0301 Montpellier 2, Laboratoire \u2018Ecologie Microbienne des Insectes et Interactions Ho\u0302te-Pathoge\u0300ne\u2019, 34095 Montpellier, France","Universit\u00e9 Montpellier 2, Laboratoire 'Ecologie Microbienne des Insectes et Interactions H\u00f4te-Pathog\u00e8ne', 34095 Montpellier, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"INRA and","institution_ids":["https://openalex.org/I1314251682","https://openalex.org/I4387154544"]},{"raw_affiliation_string":"Universite\u0301 Montpellier 2, Laboratoire \u2018Ecologie Microbienne des Insectes et Interactions Ho\u0302te-Pathoge\u0300ne\u2019, 34095 Montpellier, France","institution_ids":["https://openalex.org/I4387154756"]},{"raw_affiliation_string":"Universit\u00e9 Montpellier 2, Laboratoire 'Ecologie Microbienne des Insectes et Interactions H\u00f4te-Pathog\u00e8ne', 34095 Montpellier, France","institution_ids":["https://openalex.org/I4387154756"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5072020647","display_name":"Didier Mazel","orcid":"https://orcid.org/0000-0001-6482-6002","observed_orcids":["https://orcid.org/0000-0001-6482-6002"]},"institutions":[{"id":"https://openalex.org/I1294671590","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73","country_code":"FR","type":"government","lineage":["https://openalex.org/I1294671590"]},{"id":"https://openalex.org/I157536573","display_name":"Institut Pasteur","ror":"https://ror.org/0495fxg12","country_code":"FR","type":"nonprofit","lineage":["https://openalex.org/I157536573"]},{"id":"https://openalex.org/I4210162100","display_name":"Department of Genomes & Genetics","ror":"https://ror.org/05etkex69","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I157536573","https://openalex.org/I4210096427","https://openalex.org/I4210162100"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Didier Mazel","raw_affiliation_strings":["Institut Pasteur, CNRS, URA 2171, Laboratoire \u2018Plasticite\u0301 du ge\u0301nome bacte\u0301rien\u2019, 75015 Paris, France","Institut Pasteur, CNRS, URA 2171, Laboratoire 'Plasticit\u00e9 du g\u00e9nome bact\u00e9rien', 75015 Paris, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institut Pasteur, CNRS, URA 2171, Laboratoire \u2018Plasticite\u0301 du ge\u0301nome bacte\u0301rien\u2019, 75015 Paris, France","institution_ids":["https://openalex.org/I1294671590","https://openalex.org/I157536573","https://openalex.org/I4210162100"]},{"raw_affiliation_string":"Institut Pasteur, CNRS, URA 2171, Laboratoire 'Plasticit\u00e9 du g\u00e9nome bact\u00e9rien', 75015 Paris, France","institution_ids":["https://openalex.org/I1294671590","https://openalex.org/I157536573","https://openalex.org/I4210162100"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5063689405","display_name":"Evelyne Bach\u00e8re","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1294671590","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73","country_code":"FR","type":"government","lineage":["https://openalex.org/I1294671590"]},{"id":"https://openalex.org/I154202486","display_name":"Ifremer","ror":"https://ror.org/044jxhp58","country_code":"FR","type":"facility","lineage":["https://openalex.org/I154202486"]},{"id":"https://openalex.org/I19894307","display_name":"Universit\u00e9 de Montpellier","ror":"https://ror.org/051escj72","country_code":"FR","type":"education","lineage":["https://openalex.org/I19894307"]},{"id":"https://openalex.org/I4387154756","display_name":"Universit\u00e9 Montpellier 2","ror":"https://ror.org/00wh4bp03","country_code":"FR","type":"education","lineage":["https://openalex.org/I19894307","https://openalex.org/I4387154756"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Evelyne Bach\u00e8re","raw_affiliation_strings":["CNRS, UMR 5119, Laboratoire \u2018Ecosyste\u0300mes lagunaires\u2019, Universite\u0301 Montpellier 2, 34095 Montpellier, France","Ifremer and","Universite\u0301 Montpellier 2, Laboratoire \u2018Ecosyste\u0300mes lagunaires\u2019, 34095 Montpellier, France","CNRS, UMR 5119, Laboratoire 'Ecosyst\u00e8mes lagunaires', Universit\u00e9 Montpellier 2, 34095 Montpellier, France","Universit\u00e9 Montpellier 2, Laboratoire 'Ecosyst\u00e8mes lagunaires', 34095 Montpellier, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"CNRS, UMR 5119, Laboratoire \u2018Ecosyste\u0300mes lagunaires\u2019, Universite\u0301 Montpellier 2, 34095 Montpellier, France","institution_ids":["https://openalex.org/I1294671590","https://openalex.org/I19894307","https://openalex.org/I4387154756"]},{"raw_affiliation_string":"Ifremer and","institution_ids":["https://openalex.org/I154202486"]},{"raw_affiliation_string":"Universite\u0301 Montpellier 2, Laboratoire \u2018Ecosyste\u0300mes lagunaires\u2019, 34095 Montpellier, France","institution_ids":["https://openalex.org/I4387154756"]},{"raw_affiliation_string":"CNRS, UMR 5119, Laboratoire 'Ecosyst\u00e8mes lagunaires', Universit\u00e9 Montpellier 2, 34095 Montpellier, France","institution_ids":["https://openalex.org/I1294671590","https://openalex.org/I19894307","https://openalex.org/I4387154756"]},{"raw_affiliation_string":"Universit\u00e9 Montpellier 2, Laboratoire 'Ecosyst\u00e8mes lagunaires', 34095 Montpellier, France","institution_ids":["https://openalex.org/I4387154756"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5067185392","display_name":"Delphine Destoumieux\u2010Garz\u00f3n","orcid":"https://orcid.org/0000-0002-8793-9138","observed_orcids":["https://orcid.org/0000-0002-8793-9138"]},"institutions":[{"id":"https://openalex.org/I1294671590","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73","country_code":"FR","type":"government","lineage":["https://openalex.org/I1294671590"]},{"id":"https://openalex.org/I154202486","display_name":"Ifremer","ror":"https://ror.org/044jxhp58","country_code":"FR","type":"facility","lineage":["https://openalex.org/I154202486"]},{"id":"https://openalex.org/I19894307","display_name":"Universit\u00e9 de Montpellier","ror":"https://ror.org/051escj72","country_code":"FR","type":"education","lineage":["https://openalex.org/I19894307"]},{"id":"https://openalex.org/I4387154756","display_name":"Universit\u00e9 Montpellier 2","ror":"https://ror.org/00wh4bp03","country_code":"FR","type":"education","lineage":["https://openalex.org/I19894307","https://openalex.org/I4387154756"]}],"countries":["FR"],"is_corresponding":true,"raw_author_name":"Delphine Destoumieux\u2010Garz\u00f3n","raw_affiliation_strings":["CNRS, UMR 5119, Laboratoire \u2018Ecosyste\u0300mes lagunaires\u2019, Universite\u0301 Montpellier 2, 34095 Montpellier, France","Ifremer and","Universite\u0301 Montpellier 2, Laboratoire \u2018Ecosyste\u0300mes lagunaires\u2019, 34095 Montpellier, France","CNRS, UMR 5119, Laboratoire 'Ecosyst\u00e8mes lagunaires', Universit\u00e9 Montpellier 2, 34095 Montpellier, France","Universit\u00e9 Montpellier 2, Laboratoire 'Ecosyst\u00e8mes lagunaires', 34095 Montpellier, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"CNRS, UMR 5119, Laboratoire \u2018Ecosyste\u0300mes lagunaires\u2019, Universite\u0301 Montpellier 2, 34095 Montpellier, France","institution_ids":["https://openalex.org/I1294671590","https://openalex.org/I19894307","https://openalex.org/I4387154756"]},{"raw_affiliation_string":"Ifremer and","institution_ids":["https://openalex.org/I154202486"]},{"raw_affiliation_string":"Universite\u0301 Montpellier 2, Laboratoire \u2018Ecosyste\u0300mes lagunaires\u2019, 34095 Montpellier, France","institution_ids":["https://openalex.org/I4387154756"]},{"raw_affiliation_string":"CNRS, UMR 5119, Laboratoire 'Ecosyst\u00e8mes lagunaires', Universit\u00e9 Montpellier 2, 34095 Montpellier, France","institution_ids":["https://openalex.org/I1294671590","https://openalex.org/I19894307","https://openalex.org/I4387154756"]},{"raw_affiliation_string":"Universit\u00e9 Montpellier 2, Laboratoire 'Ecosyst\u00e8mes lagunaires', 34095 Montpellier, France","institution_ids":["https://openalex.org/I4387154756"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":8,"corresponding_author_ids":["https://openalex.org/A5067185392"],"corresponding_institution_ids":["https://openalex.org/I1294671590","https://openalex.org/I154202486","https://openalex.org/I19894307","https://openalex.org/I4387154756"],"apc_list":{"value":4640,"currency":"USD","value_usd":4640},"apc_paid":null,"fwci":6.4264,"has_fulltext":true,"cited_by_count":123,"citation_normalized_percentile":{"value":0.97245984,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":95,"max":100},"biblio":{"volume":"12","issue":"4","first_page":"951","last_page":"963"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11684","display_name":"Vibrio bacteria research studies","score":0.6845999956130981,"subfield":{"id":"https://openalex.org/subfields/2404","display_name":"Microbiology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11684","display_name":"Vibrio bacteria research studies","score":0.6845999956130981,"subfield":{"id":"https://openalex.org/subfields/2404","display_name":"Microbiology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10506","display_name":"Aquaculture disease management and microbiota","score":0.13109999895095825,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11403","display_name":"Invertebrate Immune Response Mechanisms","score":0.0430000014603138,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/vibrio-splendidus","display_name":"Vibrio splendidus","score":0.9919999837875366},{"id":"https://openalex.org/keywords/crassostrea-gigas","display_name":"Crassostrea gigas","score":0.9190000295639038},{"id":"https://openalex.org/keywords/outer-membrane-proteins","display_name":"outer membrane proteins","score":0.9210000038146973},{"id":"https://openalex.org/keywords/antimicrobial-peptide-resistance","display_name":"antimicrobial peptide resistance","score":0.9710000157356262},{"id":"https://openalex.org/keywords/defensins","display_name":"defensins","score":0.7179999947547913},{"id":"https://openalex.org/keywords/bactericidal-permeability-increasing-protein","display_name":"bactericidal/permeability-increasing protein","score":0.9829999804496765},{"id":"https://openalex.org/keywords/virulence","display_name":"virulence","score":0.6010000109672546},{"id":"https://openalex.org/keywords/oyster-mortality","display_name":"oyster mortality","score":0.5600000023841858},{"id":"https://openalex.org/keywords/host-pathogen-interaction","display_name":"host-pathogen interaction","score":0.7599999904632568},{"id":"https://openalex.org/keywords/summer-mortality","display_name":"summer mortality","score":0.7059999704360962}],"concepts":[{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.9165008068084717},{"id":"https://openalex.org/C89423630","wikidata":"https://www.wikidata.org/wiki/Q7193","display_name":"Microbiology","level":1,"score":0.8432404398918152},{"id":"https://openalex.org/C2776845067","wikidata":"https://www.wikidata.org/wiki/Q542708","display_name":"Crassostrea","level":3,"score":0.8227899074554443},{"id":"https://openalex.org/C60987743","wikidata":"https://www.wikidata.org/wiki/Q1460232","display_name":"Virulence","level":3,"score":0.6729453206062317},{"id":"https://openalex.org/C2776364969","wikidata":"https://www.wikidata.org/wiki/Q107411","display_name":"Oyster","level":2,"score":0.6392562985420227},{"id":"https://openalex.org/C146587185","wikidata":"https://www.wikidata.org/wiki/Q258248","display_name":"Bacterial outer membrane","level":4,"score":0.5418568253517151},{"id":"https://openalex.org/C2776154503","wikidata":"https://www.wikidata.org/wiki/Q753490","display_name":"Vibrio","level":3,"score":0.44059455394744873},{"id":"https://openalex.org/C2776498113","wikidata":"https://www.wikidata.org/wiki/Q412820","display_name":"Defensin","level":3,"score":0.42645198106765747},{"id":"https://openalex.org/C2776460866","wikidata":"https://www.wikidata.org/wiki/Q170065","display_name":"Pathogen","level":2,"score":0.4234223961830139},{"id":"https://openalex.org/C2909477668","wikidata":"https://www.wikidata.org/wiki/Q753490","display_name":"Vibrio Infections","level":4,"score":0.4143039882183075},{"id":"https://openalex.org/C4937899","wikidata":"https://www.wikidata.org/wiki/Q68541106","display_name":"Antimicrobial","level":2,"score":0.29231980443000793},{"id":"https://openalex.org/C523546767","wikidata":"https://www.wikidata.org/wiki/Q10876","display_name":"Bacteria","level":2,"score":0.23050454258918762},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.12216845154762268},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.09410563111305237},{"id":"https://openalex.org/C547475151","wikidata":"https://www.wikidata.org/wiki/Q25419","display_name":"Escherichia coli","level":3,"score":0.07824736833572388},{"id":"https://openalex.org/C18903297","wikidata":"https://www.wikidata.org/wiki/Q7150","display_name":"Ecology","level":1,"score":0.07229235768318176}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001798","descriptor_name":"Blood Proteins","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D005816","descriptor_name":"Genetic Complementation Test","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009154","descriptor_name":"Mutation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014733","descriptor_name":"Vibrio","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D014733","descriptor_name":"Vibrio","qualifier_ui":"Q000472","qualifier_name":"pathogenicity","is_major_topic":true},{"descriptor_ui":"D014735","descriptor_name":"Vibrio Infections","qualifier_ui":"Q000382","qualifier_name":"microbiology","is_major_topic":true},{"descriptor_ui":"D014774","descriptor_name":"Virulence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017353","descriptor_name":"Gene Deletion","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018829","descriptor_name":"Adhesins, Bacterial","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D018829","descriptor_name":"Adhesins, Bacterial","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D023181","descriptor_name":"Antimicrobial Cationic Peptides","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D049896","descriptor_name":"Crassostrea","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D049896","descriptor_name":"Crassostrea","qualifier_ui":"Q000382","qualifier_name":"microbiology","is_major_topic":true}],"locations_count":4,"locations":[{"id":"doi:10.1111/j.1462-2920.2009.02138.x","doi":"https://doi.org/10.1111/j.1462-2920.2009.02138.x","is_oa":true,"landing_page_url":"https://doi.org/10.1111/j.1462-2920.2009.02138.x","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/j.1462-2920.2009.02138.x","source":{"id":"https://openalex.org/S6919857","display_name":"Environmental Microbiology","issn_l":"1462-2912","issn":["1462-2912","1462-2920"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Environmental Microbiology","raw_type":"journal-article"},{"id":"pmid:20074236","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/20074236","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Environmental microbiology","raw_type":"Journal Article"},{"id":"pmh:oai:HAL:hal-02667966v1","doi":null,"is_oa":false,"landing_page_url":"https://hal.inrae.fr/hal-02667966","pdf_url":null,"source":{"id":"https://openalex.org/S4306402512","display_name":"HAL","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4405252976","host_organization_name":"Centre pour la Communication Scientifique Directe","host_organization_lineage":["https://openalex.org/I4405252976"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Environmental Microbiology, 2010, 12 (4), pp.951-963. &#x27E8;10.1111/j.1462-2920.2009.02138.x&#x27E9;","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:archimer.ifremer.fr:11421","doi":null,"is_oa":false,"landing_page_url":"https://archimer.ifremer.fr/doc/00003/11421/","pdf_url":null,"source":{"id":"https://openalex.org/S4377196267","display_name":"Institutional Archive of Ifremer (French Research Institute for Exploitation of the Sea)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I154202486","host_organization_name":"Ifremer","host_organization_lineage":["https://openalex.org/I154202486"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Environmental Microbiology (1462-2912) (Wiley-blackwell Publishing, Inc), 2010-04 , Vol. 12 , N. 4 , P. 951-963","raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":{"id":"doi:10.1111/j.1462-2920.2009.02138.x","doi":"https://doi.org/10.1111/j.1462-2920.2009.02138.x","is_oa":true,"landing_page_url":"https://doi.org/10.1111/j.1462-2920.2009.02138.x","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/j.1462-2920.2009.02138.x","source":{"id":"https://openalex.org/S6919857","display_name":"Environmental Microbiology","issn_l":"1462-2912","issn":["1462-2912","1462-2920"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Environmental Microbiology","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Life below water","score":0.5769000053405762,"id":"https://metadata.un.org/sdg/14"}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320322892","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2129885366.pdf","grobid_xml":"https://content.openalex.org/works/W2129885366.grobid-xml"},"referenced_works_count":51,"referenced_works":["https://openalex.org/W1785988267","https://openalex.org/W1919954453","https://openalex.org/W1964104911","https://openalex.org/W1970977166","https://openalex.org/W1971870251","https://openalex.org/W1979300931","https://openalex.org/W1980120566","https://openalex.org/W1989998611","https://openalex.org/W2000802512","https://openalex.org/W2007319738","https://openalex.org/W2022896980","https://openalex.org/W2026482455","https://openalex.org/W2037284608","https://openalex.org/W2037685605","https://openalex.org/W2058376506","https://openalex.org/W2081960029","https://openalex.org/W2082666793","https://openalex.org/W2088355493","https://openalex.org/W2089175291","https://openalex.org/W2097705352","https://openalex.org/W2098603978","https://openalex.org/W2100131579","https://openalex.org/W2105789977","https://openalex.org/W2111759307","https://openalex.org/W2114452222","https://openalex.org/W2119889633","https://openalex.org/W2120821277","https://openalex.org/W2123157959","https://openalex.org/W2125069840","https://openalex.org/W2125905899","https://openalex.org/W2125965145","https://openalex.org/W2126576412","https://openalex.org/W2128414688","https://openalex.org/W2136999630","https://openalex.org/W2137590150","https://openalex.org/W2138497186","https://openalex.org/W2149298707","https://openalex.org/W2149358967","https://openalex.org/W2150623405","https://openalex.org/W2152370826","https://openalex.org/W2155736667","https://openalex.org/W2160043086","https://openalex.org/W2160185596","https://openalex.org/W2163060579","https://openalex.org/W2166616050","https://openalex.org/W2167803442","https://openalex.org/W2170649701","https://openalex.org/W2232359229","https://openalex.org/W2329712617","https://openalex.org/W2337609611","https://openalex.org/W3041047318"],"related_works":["https://openalex.org/W1567121095","https://openalex.org/W6992958641","https://openalex.org/W7143305194","https://openalex.org/W2134051754","https://openalex.org/W3210764610","https://openalex.org/W2968584482","https://openalex.org/W4394974247","https://openalex.org/W2028554632","https://openalex.org/W2144588212","https://openalex.org/W3014070908"],"abstract_inverted_index":{"Vibrio":[0,21],"splendidus,":[1,208],"strain":[2,179],"LGP32,":[3],"is":[4,192],"an":[5,221],"oyster":[6,54,143,150],"pathogen":[7],"associated":[8],"with":[9,180],"the":[10,14,69,104,120,147,170,177,184,216,225],"summer":[11],"mortalities":[12,151],"affecting":[13],"production":[15],"of":[16,91,95,103,122,138,186,196,224],"Crassostrea":[17],"gigas":[18,48],"oysters":[19],"worldwide.":[20],"splendidus":[22,124,140,228],"LGP32":[23,125],"was":[24,66,86,101,132,173],"shown":[25],"to":[26,28,30,52,82,98,116,126,155,200,206],"resist":[27],"up":[29,81],"10":[31],"microM":[32],"Cg-Def":[33,55],"defensin":[34],"and":[35,56,58,209],"Cg-BPI":[36,57],"bactericidal":[37,77],"permeability":[38],"increasing":[39],"protein,":[40],"two":[41],"antimicrobial":[42],"peptides/proteins":[43],"(AMPs)":[44],"involved":[45],"in":[46,111,129,142,167,183,213],"C.":[47,226],"immunity.":[49],"The":[50,93],"resistance":[51,85],"both":[53],"standard":[59],"AMPs":[60],"(polymyxin":[61],"B,":[62],"protegrin,":[63],"human":[64],"BPI)":[65],"dependent":[67],"on":[68],"ompU":[70,74,114,131,158,171,191],"gene.":[71],"Indeed,":[72,146],"upon":[73,88,157],"inactivation,":[75],"minimal":[76],"concentrations":[78],"decreased":[79],"by":[80,176],"fourfold.":[83],"AMP":[84,106,112,201],"restored":[87],"ectopic":[89],"expression":[90],"ompU.":[92],"susceptibility":[94],"bacterial":[96],"membranes":[97],"AMP-induced":[99],"damages":[100],"independent":[102],"ompU-mediated":[105],"resistance.":[107],"Besides":[108],"its":[109],"role":[110],"resistance,":[113,202],"proved":[115],"be":[117],"essential":[118,211,222],"for":[119,194,212],"adherence":[121],"V.":[123,139,148,197,207],"fibronectin.":[127],"Interestingly,":[128],"vivo,":[130],"identified":[133],"as":[134,220],"a":[135],"major":[136],"determinant":[137],"pathogenicity":[141],"experimental":[144],"infections.":[145],"splendidus-induced":[149],"dropped":[152],"from":[153],"56%":[154],"11%":[156],"mutation":[159],"(Kaplan-Meier":[160],"survival":[161],"curves,":[162],"P":[163],"<":[164],"0.01).":[165],"Moreover,":[166],"co-infection":[168],"assays,":[169],"mutant":[172],"out":[174],"competed":[175],"wild-type":[178],"competitive":[181],"indexes":[182],"range":[185],"0.1-0.2.":[187],"From":[188],"this":[189],"study,":[190],"required":[193],"virulence":[195],"splendidus.":[198],"Contributing":[199],"conferring":[203],"adhesive":[204],"properties":[205],"being":[210],"vivo":[214],"fitness,":[215],"OmpU":[217],"porin":[218],"appears":[219],"effector":[223],"gigas/V.":[227],"interaction.":[229]},"counts_by_year":[{"year":2025,"cited_by_count":3},{"year":2024,"cited_by_count":3},{"year":2023,"cited_by_count":7},{"year":2022,"cited_by_count":5},{"year":2021,"cited_by_count":6},{"year":2020,"cited_by_count":6},{"year":2019,"cited_by_count":11},{"year":2018,"cited_by_count":13},{"year":2017,"cited_by_count":7},{"year":2016,"cited_by_count":5},{"year":2015,"cited_by_count":15},{"year":2014,"cited_by_count":15},{"year":2013,"cited_by_count":7},{"year":2012,"cited_by_count":8}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2016-06-24T00:00:00"}