{"id":"https://openalex.org/W2129807435","doi":"https://doi.org/10.3389/fncel.2014.00154","title":"Chemokines in the balance: maintenance of homeostasis and protection at CNS barriers","display_name":"Chemokines in the balance: maintenance of homeostasis and protection at CNS barriers","publication_year":2014,"publication_date":"2014-05-28","ids":{"openalex":"https://openalex.org/W2129807435","doi":"https://doi.org/10.3389/fncel.2014.00154","mag":"2129807435","pmid":"https://pubmed.ncbi.nlm.nih.gov/24920943","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/4036130"},"language":"en","primary_location":{"id":"doi:10.3389/fncel.2014.00154","doi":"https://doi.org/10.3389/fncel.2014.00154","is_oa":true,"landing_page_url":"https://doi.org/10.3389/fncel.2014.00154","pdf_url":"https://www.frontiersin.org/articles/10.3389/fncel.2014.00154/pdf","source":{"id":"https://openalex.org/S36653316","display_name":"Frontiers in Cellular Neuroscience","issn_l":"1662-5102","issn":["1662-5102"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320527","host_organization_name":"Frontiers Media","host_organization_lineage":["https://openalex.org/P4310320527"],"host_organization_lineage_names":["Frontiers Media"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in Cellular Neuroscience","raw_type":"journal-article"},"volume":null,"type":"review","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.frontiersin.org/articles/10.3389/fncel.2014.00154/pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5086179668","display_name":"Jessica Lynn Williams","orcid":"https://orcid.org/0000-0002-9801-9580","observed_orcids":["https://orcid.org/0000-0002-9801-9580","https://orcid.org/0000-0003-2694-2736"]},"institutions":[{"id":"https://openalex.org/I204465549","display_name":"Washington University in St. Louis","ror":"https://ror.org/01yc7t268","country_code":"US","type":"education","lineage":["https://openalex.org/I204465549"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jessica L. Williams","raw_affiliation_strings":["Department of Internal Medicine, Washington University School of Medicine, St. Louis, MO, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Internal Medicine, Washington University School of Medicine, St. Louis, MO, USA","institution_ids":["https://openalex.org/I204465549"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103357641","display_name":"David W. Holman","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"David W. Holman","raw_affiliation_strings":["Infectious Diseases Division, Decision Resources Group, Burlington, MA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Infectious Diseases Division, Decision Resources Group, Burlington, MA, USA","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5046722897","display_name":"Robyn S. Klein","orcid":"https://orcid.org/0000-0003-0281-1352","observed_orcids":["https://orcid.org/0000-0003-0281-1352"]},"institutions":[{"id":"https://openalex.org/I204465549","display_name":"Washington University in St. Louis","ror":"https://ror.org/01yc7t268","country_code":"US","type":"education","lineage":["https://openalex.org/I204465549"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Robyn S. Klein","raw_affiliation_strings":["Department of Internal Medicine, Washington University School of Medicine St. Louis, MO, USA ; Department of Pathology and Immunology, Washington University School of Medicine St. Louis, MO, USA ; Department of Anatomy and Neurobiology, Washington University School of Medicine St. Louis, MO, USA","Department of Anatomy and Neurobiology, Washington University School of Medicine, St. Louis, MO, USA","Department of Internal Medicine, Washington University School of Medicine, St. Louis, MO, USA","Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Internal Medicine, Washington University School of Medicine St. Louis, MO, USA ; Department of Pathology and Immunology, Washington University School of Medicine St. Louis, MO, USA ; Department of Anatomy and Neurobiology, Washington University School of Medicine St. Louis, MO, USA","institution_ids":["https://openalex.org/I204465549"]},{"raw_affiliation_string":"Department of Anatomy and Neurobiology, Washington University School of Medicine, St. Louis, MO, USA","institution_ids":["https://openalex.org/I204465549"]},{"raw_affiliation_string":"Department of Internal Medicine, Washington University School of Medicine, St. Louis, MO, USA","institution_ids":["https://openalex.org/I204465549"]},{"raw_affiliation_string":"Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO, USA","institution_ids":["https://openalex.org/I204465549"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5046722897"],"corresponding_institution_ids":["https://openalex.org/I204465549"],"apc_list":{"value":3150,"currency":"CHF","value_usd":3801},"apc_paid":{"value":3150,"currency":"CHF","value_usd":3801},"fwci":1.6563,"has_fulltext":true,"cited_by_count":161,"citation_normalized_percentile":{"value":0.86096445,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":96,"max":100},"biblio":{"volume":"8","issue":null,"first_page":"154","last_page":"154"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11532","display_name":"Chemokine receptors and signaling","score":0.9794999957084656,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11532","display_name":"Chemokine receptors and signaling","score":0.9794999957084656,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11266","display_name":"Neuroinflammation and Neurodegeneration Mechanisms","score":0.014800000004470348,"subfield":{"id":"https://openalex.org/subfields/2808","display_name":"Neurology"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11872","display_name":"Barrier Structure and Function Studies","score":0.002400000113993883,"subfield":{"id":"https://openalex.org/subfields/2808","display_name":"Neurology"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/chemokines","display_name":"chemokines","score":0.9240000247955322},{"id":"https://openalex.org/keywords/central-nervous-system-homeostasis","display_name":"CNS homeostasis","score":0.8379999995231628},{"id":"https://openalex.org/keywords/blood-brain-barrier","display_name":"blood-brain barrier","score":0.9800000190734863},{"id":"https://openalex.org/keywords/cxcl12","display_name":"CXCL12","score":0.9570000171661377},{"id":"https://openalex.org/keywords/cxcl14","display_name":"CXCL14","score":0.925000011920929},{"id":"https://openalex.org/keywords/cx3cl1","display_name":"fractalkine","score":0.9350000023841858},{"id":"https://openalex.org/keywords/ccl21","display_name":"CCL21","score":0.7020000219345093},{"id":"https://openalex.org/keywords/ccl20","display_name":"CCL20","score":0.8550000190734863},{"id":"https://openalex.org/keywords/ccl19","display_name":"CCL19","score":0.9929999709129333},{"id":"https://openalex.org/keywords/adult-neurogenesis","display_name":"adult neurogenesis","score":0.8370000123977661},{"id":"https://openalex.org/keywords/neuronal-survival","display_name":"neuronal survival","score":0.9589999914169312},{"id":"https://openalex.org/keywords/microglia","display_name":"microglia","score":0.6700000166893005},{"id":"https://openalex.org/keywords/immunosurveillance","display_name":"immune surveillance","score":0.781000018119812},{"id":"https://openalex.org/keywords/neurological-disorders","display_name":"neurological disorders","score":0.6269999742507935},{"id":"https://openalex.org/keywords/chemokine-receptors","display_name":"chemokine receptors","score":0.7570000290870667}],"concepts":[{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.6508520245552063},{"id":"https://openalex.org/C13373296","wikidata":"https://www.wikidata.org/wiki/Q421866","display_name":"Chemokine","level":3,"score":0.6220681667327881},{"id":"https://openalex.org/C63645605","wikidata":"https://www.wikidata.org/wiki/Q103191","display_name":"Homeostasis","level":2,"score":0.6068059206008911},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.6001917719841003},{"id":"https://openalex.org/C87753298","wikidata":"https://www.wikidata.org/wiki/Q17157137","display_name":"Neuroinflammation","level":3,"score":0.5197510123252869},{"id":"https://openalex.org/C2776885095","wikidata":"https://www.wikidata.org/wiki/Q1059","display_name":"Immunosurveillance","level":3,"score":0.49118849635124207},{"id":"https://openalex.org/C2779830541","wikidata":"https://www.wikidata.org/wiki/Q1622829","display_name":"Microglia","level":3,"score":0.4558999240398407},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.4546317756175995},{"id":"https://openalex.org/C4746552","wikidata":"https://www.wikidata.org/wiki/Q1456827","display_name":"Neurogenesis","level":2,"score":0.43668726086616516},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.3230993151664734},{"id":"https://openalex.org/C2776914184","wikidata":"https://www.wikidata.org/wiki/Q101991","display_name":"Inflammation","level":2,"score":0.22704729437828064},{"id":"https://openalex.org/C8891405","wikidata":"https://www.wikidata.org/wiki/Q1059","display_name":"Immune system","level":2,"score":0.15999311208724976}],"mesh":[],"locations_count":5,"locations":[{"id":"doi:10.3389/fncel.2014.00154","doi":"https://doi.org/10.3389/fncel.2014.00154","is_oa":true,"landing_page_url":"https://doi.org/10.3389/fncel.2014.00154","pdf_url":"https://www.frontiersin.org/articles/10.3389/fncel.2014.00154/pdf","source":{"id":"https://openalex.org/S36653316","display_name":"Frontiers in Cellular Neuroscience","issn_l":"1662-5102","issn":["1662-5102"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320527","host_organization_name":"Frontiers Media","host_organization_lineage":["https://openalex.org/P4310320527"],"host_organization_lineage_names":["Frontiers Media"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in Cellular Neuroscience","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:4036130","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/4036130","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Front Cell Neurosci","raw_type":"Text"},{"id":"pmid:24920943","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/24920943","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in cellular neuroscience","raw_type":"Journal Article"},{"id":"pmh:oai:digitalcommons.wustl.edu:open_access_pubs-3953","doi":null,"is_oa":true,"landing_page_url":"https://digitalcommons.wustl.edu/open_access_pubs/2952","pdf_url":"https://digitalcommons.wustl.edu/open_access_pubs/2952","source":{"id":"https://openalex.org/S4306400764","display_name":"Digital Commons@Becker (Washington University School of Medicine)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I204465549","host_organization_name":"Washington University in St. Louis","host_organization_lineage":["https://openalex.org/I204465549"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Open Access Publications","raw_type":"text"},{"id":"pmh:oai:doaj.org/article:41703e64da064824ac9cae92b266af00","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/41703e64da064824ac9cae92b266af00","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Frontiers in Cellular Neuroscience, Vol 8 (2014)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.3389/fncel.2014.00154","doi":"https://doi.org/10.3389/fncel.2014.00154","is_oa":true,"landing_page_url":"https://doi.org/10.3389/fncel.2014.00154","pdf_url":"https://www.frontiersin.org/articles/10.3389/fncel.2014.00154/pdf","source":{"id":"https://openalex.org/S36653316","display_name":"Frontiers in Cellular Neuroscience","issn_l":"1662-5102","issn":["1662-5102"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320527","host_organization_name":"Frontiers Media","host_organization_lineage":["https://openalex.org/P4310320527"],"host_organization_lineage_names":["Frontiers Media"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in Cellular Neuroscience","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.9391000270843506,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G1874686252","display_name":"Center for the Study of Immune Mechanisms of Flavivirus Control","funder_award_id":"U19AI083019","funder_id":"https://openalex.org/F4320337355","funder_display_name":"National Institute of Allergy and Infectious Diseases"}],"funders":[{"id":"https://openalex.org/F4320337355","display_name":"National Institute of Allergy and Infectious Diseases","ror":"https://ror.org/043z4tv69"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2129807435.pdf","grobid_xml":"https://content.openalex.org/works/W2129807435.grobid-xml"},"referenced_works_count":136,"referenced_works":["https://openalex.org/W109974507","https://openalex.org/W178678712","https://openalex.org/W1491281366","https://openalex.org/W1498047155","https://openalex.org/W1516543286","https://openalex.org/W1524059733","https://openalex.org/W1537154782","https://openalex.org/W1582134010","https://openalex.org/W1595573791","https://openalex.org/W1791569952","https://openalex.org/W1959046600","https://openalex.org/W1959628805","https://openalex.org/W1963940970","https://openalex.org/W1965681567","https://openalex.org/W1971221166","https://openalex.org/W1973935154","https://openalex.org/W1977091420","https://openalex.org/W1977257270","https://openalex.org/W1982467145","https://openalex.org/W1985626362","https://openalex.org/W1987265891","https://openalex.org/W1987391422","https://openalex.org/W1987776382","https://openalex.org/W1989528460","https://openalex.org/W1992466747","https://openalex.org/W1994995252","https://openalex.org/W1996055705","https://openalex.org/W1999321510","https://openalex.org/W1999811077","https://openalex.org/W1999952543","https://openalex.org/W2002695255","https://openalex.org/W2007287932","https://openalex.org/W2007618030","https://openalex.org/W2012253237","https://openalex.org/W2012707242","https://openalex.org/W2013362521","https://openalex.org/W2015198542","https://openalex.org/W2015412022","https://openalex.org/W2018078168","https://openalex.org/W2020319641","https://openalex.org/W2020756145","https://openalex.org/W2025732663","https://openalex.org/W2026171674","https://openalex.org/W2026565203","https://openalex.org/W2026598324","https://openalex.org/W2029190354","https://openalex.org/W2031407988","https://openalex.org/W2031786917","https://openalex.org/W2032360189","https://openalex.org/W2033617297","https://openalex.org/W2034387476","https://openalex.org/W2034990013","https://openalex.org/W2036949392","https://openalex.org/W2039669922","https://openalex.org/W2043605366","https://openalex.org/W2046842929","https://openalex.org/W2047925020","https://openalex.org/W2057601511","https://openalex.org/W2057608998","https://openalex.org/W2059905231","https://openalex.org/W2061859660","https://openalex.org/W2063620236","https://openalex.org/W2063932784","https://openalex.org/W2064681773","https://openalex.org/W2065186655","https://openalex.org/W2065754676","https://openalex.org/W2066027939","https://openalex.org/W2066599974","https://openalex.org/W2067163875","https://openalex.org/W2067856703","https://openalex.org/W2068376754","https://openalex.org/W2070105244","https://openalex.org/W2070306500","https://openalex.org/W2071173565","https://openalex.org/W2077783001","https://openalex.org/W2079365338","https://openalex.org/W2080881511","https://openalex.org/W2081273376","https://openalex.org/W2081558146","https://openalex.org/W2084652820","https://openalex.org/W2084862813","https://openalex.org/W2085600478","https://openalex.org/W2087565932","https://openalex.org/W2089204174","https://openalex.org/W2090476586","https://openalex.org/W2093818708","https://openalex.org/W2094660330","https://openalex.org/W2096330567","https://openalex.org/W2096500024","https://openalex.org/W2097329773","https://openalex.org/W2099005297","https://openalex.org/W2099516158","https://openalex.org/W2100232740","https://openalex.org/W2102540234","https://openalex.org/W2108340830","https://openalex.org/W2108875285","https://openalex.org/W2111800376","https://openalex.org/W2115284469","https://openalex.org/W2117674127","https://openalex.org/W2117712783","https://openalex.org/W2118730986","https://openalex.org/W2120911948","https://openalex.org/W2122665472","https://openalex.org/W2125935825","https://openalex.org/W2126088489","https://openalex.org/W2126680127","https://openalex.org/W2128381336","https://openalex.org/W2129134090","https://openalex.org/W2131656451","https://openalex.org/W2136638612","https://openalex.org/W2136932131","https://openalex.org/W2137276142","https://openalex.org/W2137529828","https://openalex.org/W2138991824","https://openalex.org/W2141253596","https://openalex.org/W2145235967","https://openalex.org/W2145384905","https://openalex.org/W2148898943","https://openalex.org/W2149703418","https://openalex.org/W2151400960","https://openalex.org/W2153044787","https://openalex.org/W2159252214","https://openalex.org/W2161465706","https://openalex.org/W2161509677","https://openalex.org/W2161766823","https://openalex.org/W2163135664","https://openalex.org/W2163487275","https://openalex.org/W2163759450","https://openalex.org/W2166905638","https://openalex.org/W2166964263","https://openalex.org/W2171581347","https://openalex.org/W2190720904","https://openalex.org/W3041700301","https://openalex.org/W4229548424","https://openalex.org/W6635642006","https://openalex.org/W6655632121"],"related_works":["https://openalex.org/W2093352510","https://openalex.org/W2150646956","https://openalex.org/W2138844641","https://openalex.org/W2028762442","https://openalex.org/W2022448315","https://openalex.org/W2081558146","https://openalex.org/W2966798378","https://openalex.org/W1585492421","https://openalex.org/W2980407841","https://openalex.org/W2149467065"],"abstract_inverted_index":{"In":[0,170],"the":[1,30,58,61,83,88,115,175,186,189],"adult":[2,105],"central":[3],"nervous":[4],"system":[5],"(CNS),":[6],"chemokines":[7,38,54,78,183],"and":[8,16,43,70,107,140,180],"their":[9,26,193],"receptors":[10],"are":[11,55],"involved":[12,99],"in":[13,100,154],"developmental,":[14],"physiological":[15],"pathological":[17],"processes.":[18],"Although":[19],"most":[20],"lines":[21],"of":[22,32,60,76,85,130,150,178,192,198],"investigation":[23],"focus":[24],"on":[25,57],"ability":[27],"to":[28,81,114,121,125,165],"induce":[29],"migration":[31],"cells,":[33],"recent":[34],"studies":[35],"indicate":[36,94],"that":[37,47,95,136,155],"also":[39,98],"promote":[40],"cellular":[41,102],"interactions":[42],"activate":[44],"signaling":[45],"pathways":[46],"maintain":[48],"CNS":[49,89],"homeostatic":[50,53,116,134,182],"functions.":[51],"Many":[52],"expressed":[56,184],"vasculature":[59],"blood":[62],"brain":[63],"barrier":[64],"(BBB)":[65],"including":[66,104,188],"CXCL12,":[67],"CCL19,":[68],"CCL20,":[69],"CCL21.":[71],"While":[72],"endothelial":[73],"cell":[74],"expression":[75,129,161],"these":[77,179],"is":[79,97,144,152],"known":[80],"regulate":[82,122,158],"entry":[84],"leukocytes":[86],"into":[87],"during":[90],"immunosurveillance,":[91],"new":[92],"data":[93],"CXCL12":[96,151],"diverse":[101,176],"activities":[103],"neurogenesis":[106],"neuronal":[108,138],"survival,":[109],"having":[110],"an":[111],"opposing":[112],"role":[113],"chemokine,":[117],"CXCL14,":[118],"which":[119],"appears":[120],"synaptic":[123],"inputs":[124],"neural":[126],"precursors.":[127],"Neuronal":[128],"CX3CL1,":[131],"yet":[132],"another":[133],"chemokine":[135],"promotes":[137],"survival":[139],"communication":[141],"with":[142],"microglia,":[143],"partly":[145],"regulated":[146],"by":[147],"CXCL12.":[148],"Regulation":[149],"unique":[153],"it":[156],"may":[157],"its":[159,166],"own":[160],"levels":[162],"via":[163],"binding":[164],"scavenger":[167],"receptor":[168],"CXCR7/ACKR3.":[169],"this":[171],"review,":[172],"we":[173],"explore":[174],"roles":[177],"other":[181],"within":[185],"CNS,":[187],"possible":[190],"implications":[191],"dysfunction":[194],"as":[195],"a":[196],"cause":[197],"neurologic":[199],"disease.":[200]},"counts_by_year":[{"year":2026,"cited_by_count":6},{"year":2025,"cited_by_count":15},{"year":2024,"cited_by_count":20},{"year":2023,"cited_by_count":13},{"year":2022,"cited_by_count":13},{"year":2021,"cited_by_count":19},{"year":2020,"cited_by_count":12},{"year":2019,"cited_by_count":10},{"year":2018,"cited_by_count":9},{"year":2017,"cited_by_count":17},{"year":2016,"cited_by_count":14},{"year":2015,"cited_by_count":10},{"year":2014,"cited_by_count":3}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}
