{"id":"https://openalex.org/W2129787307","doi":"https://doi.org/10.1016/j.jamcollsurg.2009.06.313","title":"Smad3 silencing prevents dermal fibroblast\u2013mediated collagen gel contraction","display_name":"Smad3 silencing prevents dermal fibroblast\u2013mediated collagen gel contraction","publication_year":2009,"publication_date":"2009-09-01","ids":{"openalex":"https://openalex.org/W2129787307","doi":"https://doi.org/10.1016/j.jamcollsurg.2009.06.313","mag":"2129787307"},"language":"en","primary_location":{"id":"doi:10.1016/j.jamcollsurg.2009.06.313","doi":"https://doi.org/10.1016/j.jamcollsurg.2009.06.313","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.jamcollsurg.2009.06.313","pdf_url":null,"source":{"id":"https://openalex.org/S134316426","display_name":"Journal of the American College of Surgeons","issn_l":"1072-7515","issn":["1072-7515","1879-1190"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-3","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of the American College of Surgeons","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5059934333","display_name":"John Paul Tutela","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I57206974","display_name":"New York University","ror":"https://ror.org/0190ak572","country_code":"US","type":"education","lineage":["https://openalex.org/I57206974"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"John P. Tutela","raw_affiliation_strings":["New York University, New York, NY","New York Univ, New York, NY,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"New York University, New York, NY","institution_ids":["https://openalex.org/I57206974"]},{"raw_affiliation_string":"New York Univ, New York, NY,","institution_ids":["https://openalex.org/I57206974"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5028718412","display_name":"Judy W. Lee","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I57206974","display_name":"New York University","ror":"https://ror.org/0190ak572","country_code":"US","type":"education","lineage":["https://openalex.org/I57206974"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Judy W. Lee","raw_affiliation_strings":["New York University, New York, NY","New York Univ, New York, NY,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"New York University, New York, NY","institution_ids":["https://openalex.org/I57206974"]},{"raw_affiliation_string":"New York Univ, New York, NY,","institution_ids":["https://openalex.org/I57206974"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5025755515","display_name":"Phuong D. Nguyen","orcid":"https://orcid.org/0000-0002-2116-902X","observed_orcids":["https://orcid.org/0000-0002-2116-902X"]},"institutions":[{"id":"https://openalex.org/I57206974","display_name":"New York University","ror":"https://ror.org/0190ak572","country_code":"US","type":"education","lineage":["https://openalex.org/I57206974"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Phuong D. Nguyen","raw_affiliation_strings":["New York University, New York, NY","New York Univ, New York, NY,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"New York University, New York, NY","institution_ids":["https://openalex.org/I57206974"]},{"raw_affiliation_string":"New York Univ, New York, NY,","institution_ids":["https://openalex.org/I57206974"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5042581917","display_name":"Orlando Ca\u00f1izares","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I57206974","display_name":"New York University","ror":"https://ror.org/0190ak572","country_code":"US","type":"education","lineage":["https://openalex.org/I57206974"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Orlando Canizares","raw_affiliation_strings":["New York University, New York, NY","New York Univ, New York, NY,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"New York University, New York, NY","institution_ids":["https://openalex.org/I57206974"]},{"raw_affiliation_string":"New York Univ, New York, NY,","institution_ids":["https://openalex.org/I57206974"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5039418594","display_name":"Gina K. Paek","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I57206974","display_name":"New York University","ror":"https://ror.org/0190ak572","country_code":"US","type":"education","lineage":["https://openalex.org/I57206974"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Gina K. Paek","raw_affiliation_strings":["New York University, New York, NY","New York Univ, New York, NY,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"New York University, New York, NY","institution_ids":["https://openalex.org/I57206974"]},{"raw_affiliation_string":"New York Univ, New York, NY,","institution_ids":["https://openalex.org/I57206974"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5074225322","display_name":"Cristian D. Valenzuela","orcid":"https://orcid.org/0000-0002-8694-9174","observed_orcids":["https://orcid.org/0000-0002-8694-9174"]},"institutions":[{"id":"https://openalex.org/I57206974","display_name":"New York University","ror":"https://ror.org/0190ak572","country_code":"US","type":"education","lineage":["https://openalex.org/I57206974"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Cristian Valenzuela","raw_affiliation_strings":["New York University, New York, NY","New York Univ, New York, NY,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"New York University, New York, NY","institution_ids":["https://openalex.org/I57206974"]},{"raw_affiliation_string":"New York Univ, New York, NY,","institution_ids":["https://openalex.org/I57206974"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5010766209","display_name":"Jaimie P. Levine","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I57206974","display_name":"New York University","ror":"https://ror.org/0190ak572","country_code":"US","type":"education","lineage":["https://openalex.org/I57206974"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jaimie P. Levine","raw_affiliation_strings":["New York University, New York, NY","New York Univ, New York, NY,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"New York University, New York, NY","institution_ids":["https://openalex.org/I57206974"]},{"raw_affiliation_string":"New York Univ, New York, NY,","institution_ids":["https://openalex.org/I57206974"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5086568465","display_name":"Stephen M. Warren","orcid":"https://orcid.org/0000-0002-2137-4461","observed_orcids":["https://orcid.org/0000-0002-2137-4461"]},"institutions":[{"id":"https://openalex.org/I57206974","display_name":"New York University","ror":"https://ror.org/0190ak572","country_code":"US","type":"education","lineage":["https://openalex.org/I57206974"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Stephen M. Warren","raw_affiliation_strings":["New York University, New York, NY","New York Univ, New York, NY,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"New York University, New York, NY","institution_ids":["https://openalex.org/I57206974"]},{"raw_affiliation_string":"New York Univ, New York, NY,","institution_ids":["https://openalex.org/I57206974"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5027401461","display_name":"Pierre B. Saadeh","orcid":"https://orcid.org/0000-0001-9818-8598","observed_orcids":["https://orcid.org/0000-0001-9818-8598"]},"institutions":[{"id":"https://openalex.org/I57206974","display_name":"New York University","ror":"https://ror.org/0190ak572","country_code":"US","type":"education","lineage":["https://openalex.org/I57206974"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Pierre B. Saadeh","raw_affiliation_strings":["New York University, New York, NY","New York Univ, New York, NY,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"New York University, New York, NY","institution_ids":["https://openalex.org/I57206974"]},{"raw_affiliation_string":"New York Univ, New York, NY,","institution_ids":["https://openalex.org/I57206974"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I57206974"],"apc_list":{"value":3600,"currency":"USD","value_usd":3600},"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.18017329,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"209","issue":"3","first_page":"S125","last_page":"S126"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11501","display_name":"TGF-\u03b2 signaling in diseases","score":0.45410001277923584,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11501","display_name":"TGF-\u03b2 signaling in diseases","score":0.45410001277923584,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11172","display_name":"Dermatologic Treatments and Research","score":0.32499998807907104,"subfield":{"id":"https://openalex.org/subfields/2708","display_name":"Dermatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10771","display_name":"Wound Healing and Treatments","score":0.05770000070333481,"subfield":{"id":"https://openalex.org/subfields/2742","display_name":"Rehabilitation"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/smad3","display_name":"Smad3","score":0.9639999866485596},{"id":"https://openalex.org/keywords/dermal-fibroblasts","display_name":"dermal fibroblasts","score":0.875},{"id":"https://openalex.org/keywords/collagen-gel-contraction","display_name":"collagen gel contraction","score":0.9980000257492065},{"id":"https://openalex.org/keywords/gene-silencing","display_name":"gene silencing","score":0.8040000200271606},{"id":"https://openalex.org/keywords/wound-healing","display_name":"wound healing","score":0.7400000095367432},{"id":"https://openalex.org/keywords/fibroblast-contractility","display_name":"fibroblast contractility","score":0.5400000214576721},{"id":"https://openalex.org/keywords/wound-closure","display_name":"wound closure","score":0.33000001311302185}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8519905805587769},{"id":"https://openalex.org/C2780381497","wikidata":"https://www.wikidata.org/wiki/Q463418","display_name":"Fibroblast","level":3,"score":0.661337673664093},{"id":"https://openalex.org/C163415756","wikidata":"https://www.wikidata.org/wiki/Q126473","display_name":"Contraction (grammar)","level":2,"score":0.5930521488189697},{"id":"https://openalex.org/C119056186","wikidata":"https://www.wikidata.org/wiki/Q1431332","display_name":"Gene silencing","level":3,"score":0.5302241444587708},{"id":"https://openalex.org/C2778005187","wikidata":"https://www.wikidata.org/wiki/Q5262669","display_name":"Dermal fibroblast","level":4,"score":0.4843769967556},{"id":"https://openalex.org/C153911025","wikidata":"https://www.wikidata.org/wiki/Q7202","display_name":"Molecular biology","level":1,"score":0.3772444725036621},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.2491167187690735},{"id":"https://openalex.org/C202751555","wikidata":"https://www.wikidata.org/wiki/Q221681","display_name":"In vitro","level":2,"score":0.13544699549674988},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.10740545392036438},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.0},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1016/j.jamcollsurg.2009.06.313","doi":"https://doi.org/10.1016/j.jamcollsurg.2009.06.313","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.jamcollsurg.2009.06.313","pdf_url":null,"source":{"id":"https://openalex.org/S134316426","display_name":"Journal of the American College of Surgeons","issn_l":"1072-7515","issn":["1072-7515","1879-1190"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-3","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of the American College of Surgeons","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.9391000270843506,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2283680233","https://openalex.org/W2023780484","https://openalex.org/W2066380605","https://openalex.org/W2085960705","https://openalex.org/W2359056387","https://openalex.org/W2049262181","https://openalex.org/W2090589303","https://openalex.org/W1992213652","https://openalex.org/W2336223266","https://openalex.org/W7100076258"],"abstract_inverted_index":{"Tutela,":[0],"John":[1],"P.":[2,24],"MD;":[3,7,11,14,25,29],"Lee,":[4],"Judy":[5],"W.":[6],"Nguyen,":[8],"Phuong":[9],"D.":[10],"Canizares,":[12],"Orlando":[13],"Paek,":[15],"Gina":[16],"K.":[17],"BA;":[18],"Valenzuela,":[19],"Cristian":[20],"BS;":[21],"Levine,":[22],"Jaimie":[23],"Warren,":[26],"Stephen":[27],"M.":[28],"Saadeh,":[30],"Pierre":[31],"B.":[32],"MD,":[33],"FACS":[34],"Author":[35],"Information":[36]},"counts_by_year":[],"updated_date":"2026-10-01T08:54:57.152042","created_date":"2016-06-24T00:00:00"}