{"id":"https://openalex.org/W2129727255","doi":"https://doi.org/10.1093/ndt/15.3.385","title":"Prevalence of Japanese dialysis patients with an A-to-G mutation at nucleotide 3243 of the mitochondrial tRNALeu(UUR) gene","display_name":"Prevalence of Japanese dialysis patients with an A-to-G mutation at nucleotide 3243 of the mitochondrial tRNALeu(UUR) gene","publication_year":2000,"publication_date":"2000-03-01","ids":{"openalex":"https://openalex.org/W2129727255","doi":"https://doi.org/10.1093/ndt/15.3.385","mag":"2129727255","pmid":"https://pubmed.ncbi.nlm.nih.gov/10692525"},"language":"en","primary_location":{"id":"doi:10.1093/ndt/15.3.385","doi":"https://doi.org/10.1093/ndt/15.3.385","is_oa":false,"landing_page_url":"https://doi.org/10.1093/ndt/15.3.385","pdf_url":null,"source":{"id":"https://openalex.org/S186113128","display_name":"Nephrology Dialysis Transplantation","issn_l":"0931-0509","issn":["0931-0509","1460-2385"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nephrology Dialysis Transplantation","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5111050170","display_name":"Kunihiro Yamagata","orcid":"https://orcid.org/0000-0002-7407-0410","observed_orcids":["https://orcid.org/0000-0002-7407-0410"]},"institutions":[{"id":"https://openalex.org/I146399215","display_name":"University of Tsukuba","ror":"https://ror.org/02956yf07","country_code":"JP","type":"education","lineage":["https://openalex.org/I146399215"]}],"countries":["JP"],"is_corresponding":true,"raw_author_name":"Kunihiro Yamagata","raw_affiliation_strings":["Department of Internal Medicine, Institute of Clinical Medicine, University of Tsukuba and Terumo Corporation R&D Center, Tsukuba, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Internal Medicine, Institute of Clinical Medicine, University of Tsukuba and Terumo Corporation R&D Center, Tsukuba, Japan","institution_ids":["https://openalex.org/I146399215"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5017601310","display_name":"Chie Tomida","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I146399215","display_name":"University of Tsukuba","ror":"https://ror.org/02956yf07","country_code":"JP","type":"education","lineage":["https://openalex.org/I146399215"]},{"id":"https://openalex.org/I4210119124","display_name":"Terumo (Japan)","ror":"https://ror.org/02kbe5v55","country_code":"JP","type":"company","lineage":["https://openalex.org/I4210119124"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Chie Tomida","raw_affiliation_strings":["Biomedicals Inc., Japan","Department of Internal Medicine, Institute of Clinical Medicine, University of Tsukuba, 1-1-1, Tenoudai, Tsukuba 305-8575, Japan. 3243","Tsukuba Renal Disease Research Network 1Department of Internal Medicine, Institute of Clinical Medicine, University of Tsukuba and 2Terumo Corporation R&D Center, Tsukuba, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Biomedicals Inc., Japan","institution_ids":[]},{"raw_affiliation_string":"Department of Internal Medicine, Institute of Clinical Medicine, University of Tsukuba, 1-1-1, Tenoudai, Tsukuba 305-8575, Japan. 3243","institution_ids":["https://openalex.org/I146399215"]},{"raw_affiliation_string":"Tsukuba Renal Disease Research Network 1Department of Internal Medicine, Institute of Clinical Medicine, University of Tsukuba and 2Terumo Corporation R&D Center, Tsukuba, Japan","institution_ids":["https://openalex.org/I146399215","https://openalex.org/I4210119124"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Kazuiro Umeyama","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I146399215","display_name":"University of Tsukuba","ror":"https://ror.org/02956yf07","country_code":"JP","type":"education","lineage":["https://openalex.org/I146399215"]},{"id":"https://openalex.org/I4210119124","display_name":"Terumo (Japan)","ror":"https://ror.org/02kbe5v55","country_code":"JP","type":"company","lineage":["https://openalex.org/I4210119124"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Kazuiro Umeyama","raw_affiliation_strings":["Biomedicals Inc., Japan","Department of Internal Medicine, Institute of Clinical Medicine, University of Tsukuba, 1-1-1, Tenoudai, Tsukuba 305-8575, Japan. 3243","Tsukuba Renal Disease Research Network 1Department of Internal Medicine, Institute of Clinical Medicine, University of Tsukuba and 2Terumo Corporation R&D Center, Tsukuba, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Biomedicals Inc., Japan","institution_ids":[]},{"raw_affiliation_string":"Department of Internal Medicine, Institute of Clinical Medicine, University of Tsukuba, 1-1-1, Tenoudai, Tsukuba 305-8575, Japan. 3243","institution_ids":["https://openalex.org/I146399215"]},{"raw_affiliation_string":"Tsukuba Renal Disease Research Network 1Department of Internal Medicine, Institute of Clinical Medicine, University of Tsukuba and 2Terumo Corporation R&D Center, Tsukuba, Japan","institution_ids":["https://openalex.org/I146399215","https://openalex.org/I4210119124"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5074867348","display_name":"Ken-ichi Urakami","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I146399215","display_name":"University of Tsukuba","ror":"https://ror.org/02956yf07","country_code":"JP","type":"education","lineage":["https://openalex.org/I146399215"]},{"id":"https://openalex.org/I4210119124","display_name":"Terumo (Japan)","ror":"https://ror.org/02kbe5v55","country_code":"JP","type":"company","lineage":["https://openalex.org/I4210119124"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Ken-ichi Urakami","raw_affiliation_strings":["Biomedicals Inc., Japan","Department of Internal Medicine, Institute of Clinical Medicine, University of Tsukuba, 1-1-1, Tenoudai, Tsukuba 305-8575, Japan. 3243","Tsukuba Renal Disease Research Network 1Department of Internal Medicine, Institute of Clinical Medicine, University of Tsukuba and 2Terumo Corporation R&D Center, Tsukuba, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Biomedicals Inc., Japan","institution_ids":[]},{"raw_affiliation_string":"Department of Internal Medicine, Institute of Clinical Medicine, University of Tsukuba, 1-1-1, Tenoudai, Tsukuba 305-8575, Japan. 3243","institution_ids":["https://openalex.org/I146399215"]},{"raw_affiliation_string":"Tsukuba Renal Disease Research Network 1Department of Internal Medicine, Institute of Clinical Medicine, University of Tsukuba and 2Terumo Corporation R&D Center, Tsukuba, Japan","institution_ids":["https://openalex.org/I146399215","https://openalex.org/I4210119124"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5089627057","display_name":"Takashi Ishizu","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I146399215","display_name":"University of Tsukuba","ror":"https://ror.org/02956yf07","country_code":"JP","type":"education","lineage":["https://openalex.org/I146399215"]},{"id":"https://openalex.org/I4210119124","display_name":"Terumo (Japan)","ror":"https://ror.org/02kbe5v55","country_code":"JP","type":"company","lineage":["https://openalex.org/I4210119124"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Takashi Ishizu","raw_affiliation_strings":["Biomedicals Inc., Japan","Department of Internal Medicine, Institute of Clinical Medicine, University of Tsukuba, 1-1-1, Tenoudai, Tsukuba 305-8575, Japan. 3243","Tsukuba Renal Disease Research Network 1Department of Internal Medicine, Institute of Clinical Medicine, University of Tsukuba and 2Terumo Corporation R&D Center, Tsukuba, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Biomedicals Inc., Japan","institution_ids":[]},{"raw_affiliation_string":"Department of Internal Medicine, Institute of Clinical Medicine, University of Tsukuba, 1-1-1, Tenoudai, Tsukuba 305-8575, Japan. 3243","institution_ids":["https://openalex.org/I146399215"]},{"raw_affiliation_string":"Tsukuba Renal Disease Research Network 1Department of Internal Medicine, Institute of Clinical Medicine, University of Tsukuba and 2Terumo Corporation R&D Center, Tsukuba, Japan","institution_ids":["https://openalex.org/I146399215","https://openalex.org/I4210119124"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5108492990","display_name":"Kouichi Hirayama","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I146399215","display_name":"University of Tsukuba","ror":"https://ror.org/02956yf07","country_code":"JP","type":"education","lineage":["https://openalex.org/I146399215"]},{"id":"https://openalex.org/I4210119124","display_name":"Terumo (Japan)","ror":"https://ror.org/02kbe5v55","country_code":"JP","type":"company","lineage":["https://openalex.org/I4210119124"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Kouichi Hirayama","raw_affiliation_strings":["Biomedicals Inc., Japan","Department of Internal Medicine, Institute of Clinical Medicine, University of Tsukuba, 1-1-1, Tenoudai, Tsukuba 305-8575, Japan. 3243","Tsukuba Renal Disease Research Network 1Department of Internal Medicine, Institute of Clinical Medicine, University of Tsukuba and 2Terumo Corporation R&D Center, Tsukuba, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Biomedicals Inc., Japan","institution_ids":[]},{"raw_affiliation_string":"Department of Internal Medicine, Institute of Clinical Medicine, University of Tsukuba, 1-1-1, Tenoudai, Tsukuba 305-8575, Japan. 3243","institution_ids":["https://openalex.org/I146399215"]},{"raw_affiliation_string":"Tsukuba Renal Disease Research Network 1Department of Internal Medicine, Institute of Clinical Medicine, University of Tsukuba and 2Terumo Corporation R&D Center, Tsukuba, Japan","institution_ids":["https://openalex.org/I146399215","https://openalex.org/I4210119124"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113802386","display_name":"Michihiro Gotoh","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I146399215","display_name":"University of Tsukuba","ror":"https://ror.org/02956yf07","country_code":"JP","type":"education","lineage":["https://openalex.org/I146399215"]},{"id":"https://openalex.org/I4210119124","display_name":"Terumo (Japan)","ror":"https://ror.org/02kbe5v55","country_code":"JP","type":"company","lineage":["https://openalex.org/I4210119124"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Michihiro Gotoh","raw_affiliation_strings":["Biomedicals Inc., Japan","Department of Internal Medicine, Institute of Clinical Medicine, University of Tsukuba, 1-1-1, Tenoudai, Tsukuba 305-8575, Japan. 3243","Tsukuba Renal Disease Research Network 1Department of Internal Medicine, Institute of Clinical Medicine, University of Tsukuba and 2Terumo Corporation R&D Center, Tsukuba, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Biomedicals Inc., Japan","institution_ids":[]},{"raw_affiliation_string":"Department of Internal Medicine, Institute of Clinical Medicine, University of Tsukuba, 1-1-1, Tenoudai, Tsukuba 305-8575, Japan. 3243","institution_ids":["https://openalex.org/I146399215"]},{"raw_affiliation_string":"Tsukuba Renal Disease Research Network 1Department of Internal Medicine, Institute of Clinical Medicine, University of Tsukuba and 2Terumo Corporation R&D Center, Tsukuba, Japan","institution_ids":["https://openalex.org/I146399215","https://openalex.org/I4210119124"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5043651368","display_name":"Tadashi Iitsuka","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I146399215","display_name":"University of Tsukuba","ror":"https://ror.org/02956yf07","country_code":"JP","type":"education","lineage":["https://openalex.org/I146399215"]},{"id":"https://openalex.org/I4210119124","display_name":"Terumo (Japan)","ror":"https://ror.org/02kbe5v55","country_code":"JP","type":"company","lineage":["https://openalex.org/I4210119124"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Tadashi Iitsuka","raw_affiliation_strings":["Biomedicals Inc., Japan","Department of Internal Medicine, Institute of Clinical Medicine, University of Tsukuba, 1-1-1, Tenoudai, Tsukuba 305-8575, Japan. 3243","Tsukuba Renal Disease Research Network 1Department of Internal Medicine, Institute of Clinical Medicine, University of Tsukuba and 2Terumo Corporation R&D Center, Tsukuba, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Biomedicals Inc., Japan","institution_ids":[]},{"raw_affiliation_string":"Department of Internal Medicine, Institute of Clinical Medicine, University of Tsukuba, 1-1-1, Tenoudai, Tsukuba 305-8575, Japan. 3243","institution_ids":["https://openalex.org/I146399215"]},{"raw_affiliation_string":"Tsukuba Renal Disease Research Network 1Department of Internal Medicine, Institute of Clinical Medicine, University of Tsukuba and 2Terumo Corporation R&D Center, Tsukuba, Japan","institution_ids":["https://openalex.org/I146399215","https://openalex.org/I4210119124"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111634879","display_name":"Katsumi Takemura","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I146399215","display_name":"University of Tsukuba","ror":"https://ror.org/02956yf07","country_code":"JP","type":"education","lineage":["https://openalex.org/I146399215"]},{"id":"https://openalex.org/I4210119124","display_name":"Terumo (Japan)","ror":"https://ror.org/02kbe5v55","country_code":"JP","type":"company","lineage":["https://openalex.org/I4210119124"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Katsumi Takemura","raw_affiliation_strings":["Biomedicals Inc., Japan","Department of Internal Medicine, Institute of Clinical Medicine, University of Tsukuba, 1-1-1, Tenoudai, Tsukuba 305-8575, Japan. 3243","Tsukuba Renal Disease Research Network 1Department of Internal Medicine, Institute of Clinical Medicine, University of Tsukuba and 2Terumo Corporation R&D Center, Tsukuba, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Biomedicals Inc., Japan","institution_ids":[]},{"raw_affiliation_string":"Department of Internal Medicine, Institute of Clinical Medicine, University of Tsukuba, 1-1-1, Tenoudai, Tsukuba 305-8575, Japan. 3243","institution_ids":["https://openalex.org/I146399215"]},{"raw_affiliation_string":"Tsukuba Renal Disease Research Network 1Department of Internal Medicine, Institute of Clinical Medicine, University of Tsukuba and 2Terumo Corporation R&D Center, Tsukuba, Japan","institution_ids":["https://openalex.org/I146399215","https://openalex.org/I4210119124"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5005687613","display_name":"Hiroshi Kikuchi","orcid":"https://orcid.org/0000-0003-0067-4606","observed_orcids":["https://orcid.org/0000-0003-0067-4606"]},"institutions":[{"id":"https://openalex.org/I146399215","display_name":"University of Tsukuba","ror":"https://ror.org/02956yf07","country_code":"JP","type":"education","lineage":["https://openalex.org/I146399215"]},{"id":"https://openalex.org/I4210119124","display_name":"Terumo (Japan)","ror":"https://ror.org/02kbe5v55","country_code":"JP","type":"company","lineage":["https://openalex.org/I4210119124"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Hiroshi Kikuchi","raw_affiliation_strings":["Biomedicals Inc., Japan","Department of Internal Medicine, Institute of Clinical Medicine, University of Tsukuba, 1-1-1, Tenoudai, Tsukuba 305-8575, Japan. 3243","Tsukuba Renal Disease Research Network 1Department of Internal Medicine, Institute of Clinical Medicine, University of Tsukuba and 2Terumo Corporation R&D Center, Tsukuba, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Biomedicals Inc., Japan","institution_ids":[]},{"raw_affiliation_string":"Department of Internal Medicine, Institute of Clinical Medicine, University of Tsukuba, 1-1-1, Tenoudai, Tsukuba 305-8575, Japan. 3243","institution_ids":["https://openalex.org/I146399215"]},{"raw_affiliation_string":"Tsukuba Renal Disease Research Network 1Department of Internal Medicine, Institute of Clinical Medicine, University of Tsukuba and 2Terumo Corporation R&D Center, Tsukuba, Japan","institution_ids":["https://openalex.org/I146399215","https://openalex.org/I4210119124"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5020627213","display_name":"Hideko Nakamura","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I146399215","display_name":"University of Tsukuba","ror":"https://ror.org/02956yf07","country_code":"JP","type":"education","lineage":["https://openalex.org/I146399215"]},{"id":"https://openalex.org/I4210119124","display_name":"Terumo (Japan)","ror":"https://ror.org/02kbe5v55","country_code":"JP","type":"company","lineage":["https://openalex.org/I4210119124"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Hideko Nakamura","raw_affiliation_strings":["Biomedicals Inc., Japan","Department of Internal Medicine, Institute of Clinical Medicine, University of Tsukuba, 1-1-1, Tenoudai, Tsukuba 305-8575, Japan. 3243","Tsukuba Renal Disease Research Network 1Department of Internal Medicine, Institute of Clinical Medicine, University of Tsukuba and 2Terumo Corporation R&D Center, Tsukuba, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Biomedicals Inc., Japan","institution_ids":[]},{"raw_affiliation_string":"Department of Internal Medicine, Institute of Clinical Medicine, University of Tsukuba, 1-1-1, Tenoudai, Tsukuba 305-8575, Japan. 3243","institution_ids":["https://openalex.org/I146399215"]},{"raw_affiliation_string":"Tsukuba Renal Disease Research Network 1Department of Internal Medicine, Institute of Clinical Medicine, University of Tsukuba and 2Terumo Corporation R&D Center, Tsukuba, Japan","institution_ids":["https://openalex.org/I146399215","https://openalex.org/I4210119124"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5104034726","display_name":"Masaki Kobayashi","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I146399215","display_name":"University of Tsukuba","ror":"https://ror.org/02956yf07","country_code":"JP","type":"education","lineage":["https://openalex.org/I146399215"]},{"id":"https://openalex.org/I4210119124","display_name":"Terumo (Japan)","ror":"https://ror.org/02kbe5v55","country_code":"JP","type":"company","lineage":["https://openalex.org/I4210119124"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Masaki Kobayashi","raw_affiliation_strings":["Biomedicals Inc., Japan","Department of Internal Medicine, Institute of Clinical Medicine, University of Tsukuba, 1-1-1, Tenoudai, Tsukuba 305-8575, Japan. 3243","Tsukuba Renal Disease Research Network 1Department of Internal Medicine, Institute of Clinical Medicine, University of Tsukuba and 2Terumo Corporation R&D Center, Tsukuba, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Biomedicals Inc., Japan","institution_ids":[]},{"raw_affiliation_string":"Department of Internal Medicine, Institute of Clinical Medicine, University of Tsukuba, 1-1-1, Tenoudai, Tsukuba 305-8575, Japan. 3243","institution_ids":["https://openalex.org/I146399215"]},{"raw_affiliation_string":"Tsukuba Renal Disease Research Network 1Department of Internal Medicine, Institute of Clinical Medicine, University of Tsukuba and 2Terumo Corporation R&D Center, Tsukuba, Japan","institution_ids":["https://openalex.org/I146399215","https://openalex.org/I4210119124"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5108616966","display_name":"Akio K\u00f4yama","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I146399215","display_name":"University of Tsukuba","ror":"https://ror.org/02956yf07","country_code":"JP","type":"education","lineage":["https://openalex.org/I146399215"]},{"id":"https://openalex.org/I4210119124","display_name":"Terumo (Japan)","ror":"https://ror.org/02kbe5v55","country_code":"JP","type":"company","lineage":["https://openalex.org/I4210119124"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Akio Koyama","raw_affiliation_strings":["Biomedicals Inc., Japan","Department of Internal Medicine, Institute of Clinical Medicine, University of Tsukuba, 1-1-1, Tenoudai, Tsukuba 305-8575, Japan. 3243","Tsukuba Renal Disease Research Network 1Department of Internal Medicine, Institute of Clinical Medicine, University of Tsukuba and 2Terumo Corporation R&D Center, Tsukuba, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Biomedicals Inc., Japan","institution_ids":[]},{"raw_affiliation_string":"Department of Internal Medicine, Institute of Clinical Medicine, University of Tsukuba, 1-1-1, Tenoudai, Tsukuba 305-8575, Japan. 3243","institution_ids":["https://openalex.org/I146399215"]},{"raw_affiliation_string":"Tsukuba Renal Disease Research Network 1Department of Internal Medicine, Institute of Clinical Medicine, University of Tsukuba and 2Terumo Corporation R&D Center, Tsukuba, Japan","institution_ids":["https://openalex.org/I146399215","https://openalex.org/I4210119124"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5111050170"],"corresponding_institution_ids":["https://openalex.org/I146399215"],"apc_list":{"value":3474,"currency":"EUR","value_usd":3926},"apc_paid":null,"fwci":0.5978,"has_fulltext":true,"cited_by_count":15,"citation_normalized_percentile":{"value":0.59679463,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":96},"biblio":{"volume":"15","issue":"3","first_page":"385","last_page":"388"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10301","display_name":"Mitochondrial Function and Pathology","score":0.986299991607666,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10301","display_name":"Mitochondrial Function and Pathology","score":0.986299991607666,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10334","display_name":"Hearing, Cochlea, Tinnitus, Genetics","score":0.002899999963119626,"subfield":{"id":"https://openalex.org/subfields/2809","display_name":"Sensory Systems"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11027","display_name":"Metabolism and Genetic Disorders","score":0.00139999995008111,"subfield":{"id":"https://openalex.org/subfields/1308","display_name":"Clinical Biochemistry"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/mtdna-mutations","display_name":"mitochondrial DNA mutations","score":0.8240000009536743},{"id":"https://openalex.org/keywords/dialysis-patients","display_name":"dialysis patients","score":0.9319999814033508},{"id":"https://openalex.org/keywords/diabetes-mellitus","display_name":"diabetes mellitus","score":0.8019999861717224},{"id":"https://openalex.org/keywords/deafness","display_name":"deafness","score":0.7620000243186951},{"id":"https://openalex.org/keywords/end-stage-renal-disease","display_name":"end-stage renal disease","score":0.7009999752044678},{"id":"https://openalex.org/keywords/hypertrophic-cardiomyopathy","display_name":"hypertrophic cardiomyopathy","score":0.8309999704360962},{"id":"https://openalex.org/keywords/continuous-ambulatory-peritoneal-dialysis","display_name":"continuous ambulatory peritoneal dialysis","score":0.871999979019165},{"id":"https://openalex.org/keywords/prevalence","display_name":"prevalence","score":0.6069999933242798},{"id":"https://openalex.org/keywords/japanese-patients","display_name":"Japanese patients","score":0.8939999938011169}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8720035552978516},{"id":"https://openalex.org/C501734568","wikidata":"https://www.wikidata.org/wiki/Q42918","display_name":"Mutation","level":3,"score":0.5780341625213623},{"id":"https://openalex.org/C2778063415","wikidata":"https://www.wikidata.org/wiki/Q391744","display_name":"Hemodialysis","level":2,"score":0.5602622628211975},{"id":"https://openalex.org/C24586158","wikidata":"https://www.wikidata.org/wiki/Q27075","display_name":"Mitochondrial DNA","level":3,"score":0.5471129417419434},{"id":"https://openalex.org/C2779978075","wikidata":"https://www.wikidata.org/wiki/Q202301","display_name":"Dialysis","level":2,"score":0.5368825197219849},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.5333272218704224},{"id":"https://openalex.org/C2779056158","wikidata":"https://www.wikidata.org/wiki/Q1756474","display_name":"Peritoneal dialysis","level":2,"score":0.5095911026000977},{"id":"https://openalex.org/C2777614518","wikidata":"https://www.wikidata.org/wiki/Q935710","display_name":"Mitochondrial disease","level":4,"score":0.48949897289276123},{"id":"https://openalex.org/C2909406889","wikidata":"https://www.wikidata.org/wiki/Q1756474","display_name":"Continuous ambulatory peritoneal dialysis","level":3,"score":0.4608471095561981},{"id":"https://openalex.org/C555293320","wikidata":"https://www.wikidata.org/wiki/Q12206","display_name":"Diabetes mellitus","level":2,"score":0.43505072593688965},{"id":"https://openalex.org/C2994225774","wikidata":"https://www.wikidata.org/wiki/Q42918","display_name":"Gene mutation","level":4,"score":0.41510677337646484},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.37832072377204895},{"id":"https://openalex.org/C90924648","wikidata":"https://www.wikidata.org/wiki/Q120569","display_name":"Gastroenterology","level":1,"score":0.3610100746154785},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.2985605001449585},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.2981318533420563},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.10247093439102173}],"mesh":[{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000369","descriptor_name":"Aged, 80 and over","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001483","descriptor_name":"Base Sequence","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D003638","descriptor_name":"Deafness","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":false},{"descriptor_ui":"D003638","descriptor_name":"Deafness","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D003924","descriptor_name":"Diabetes Mellitus, Type 2","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":false},{"descriptor_ui":"D003924","descriptor_name":"Diabetes Mellitus, Type 2","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D004272","descriptor_name":"DNA, Mitochondrial","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005787","descriptor_name":"Gene Frequency","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006332","descriptor_name":"Cardiomegaly","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":false},{"descriptor_ui":"D006332","descriptor_name":"Cardiomegaly","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D006435","descriptor_name":"Renal Dialysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007564","descriptor_name":"Japan","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007676","descriptor_name":"Kidney Failure, Chronic","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":false},{"descriptor_ui":"D007676","descriptor_name":"Kidney Failure, Chronic","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D007676","descriptor_name":"Kidney Failure, Chronic","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008854","descriptor_name":"Microscopy, Electron","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008928","descriptor_name":"Mitochondria","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D008929","descriptor_name":"Mitochondria, Heart","qualifier_ui":"Q000648","qualifier_name":"ultrastructure","is_major_topic":false},{"descriptor_ui":"D009154","descriptor_name":"Mutation","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D009206","descriptor_name":"Myocardium","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D010531","descriptor_name":"Peritoneal Dialysis, Continuous Ambulatory","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012356","descriptor_name":"RNA, Transfer, Leu","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D014927","descriptor_name":"Wolff-Parkinson-White Syndrome","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":false},{"descriptor_ui":"D014927","descriptor_name":"Wolff-Parkinson-White Syndrome","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1093/ndt/15.3.385","doi":"https://doi.org/10.1093/ndt/15.3.385","is_oa":false,"landing_page_url":"https://doi.org/10.1093/ndt/15.3.385","pdf_url":null,"source":{"id":"https://openalex.org/S186113128","display_name":"Nephrology Dialysis Transplantation","issn_l":"0931-0509","issn":["0931-0509","1460-2385"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nephrology Dialysis Transplantation","raw_type":"journal-article"},{"id":"pmid:10692525","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/10692525","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":1.0,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":21,"referenced_works":["https://openalex.org/W164363939","https://openalex.org/W1971844958","https://openalex.org/W1979730424","https://openalex.org/W1993220873","https://openalex.org/W2012123697","https://openalex.org/W2012511847","https://openalex.org/W2019727775","https://openalex.org/W2045409504","https://openalex.org/W2050773647","https://openalex.org/W2052254021","https://openalex.org/W2052526312","https://openalex.org/W2055023561","https://openalex.org/W2057209896","https://openalex.org/W2066979699","https://openalex.org/W2102254551","https://openalex.org/W2109291482","https://openalex.org/W2126858699","https://openalex.org/W2322958337","https://openalex.org/W2338125871","https://openalex.org/W2510628653","https://openalex.org/W4248957653"],"related_works":["https://openalex.org/W2066979699","https://openalex.org/W2052254021","https://openalex.org/W2400677348","https://openalex.org/W2077203911","https://openalex.org/W2071756646","https://openalex.org/W2423996745","https://openalex.org/W2157606310","https://openalex.org/W2126858699","https://openalex.org/W2338125871","https://openalex.org/W2410982956"],"abstract_inverted_index":{"BACKGROUND:":[0],"A":[1,109],"high":[2],"prevalence":[3,30,158],"of":[4,11,31,72,83,91,127,159],"an":[5,66],"A-to-G":[6,67],"mutation":[7,33,122,143,161],"at":[8,69,144],"nucleotide":[9,70,145],"3243":[10,71,146],"the":[12,29,73,92],"mitochondrial":[13,74,141],"genome":[14],"in":[15,34,81,149,168,174],"patients":[16,37,48,85,98,173],"with":[17,38,49,52,58,86,99,153],"diabetes":[18],"mellitus":[19],"(DM)":[20],"and/or":[21,41],"deafness":[22,59,100],"has":[23],"been":[24],"reported":[25],"previously.":[26],"We":[27,44,77,137],"investigated":[28],"this":[32,79,107,121,160],"Japanese":[35],"dialysis":[36,47,97,117,151],"associated":[39],"DM":[40,53,87,94,103],"deafness.":[42,89,156],"METHODS:":[43],"studied":[45],"106":[46,93],"DM,":[50],"26":[51,57,84,96],"and":[54,56,88,155],"deafness,":[55],"alone,":[60],"using":[61],"peripheral":[62],"leucocytes":[63],"to":[64,164],"detect":[65],"transition":[68,80],"gene.":[75],"RESULTS:":[76],"identified":[78],"1":[82],"None":[90],"or":[95],"but":[101],"no":[102],"was":[104,147,162],"positive":[105],"for":[106],"mutation.":[108],"42-year-old":[110],"male":[111],"patient":[112,152],"on":[113],"continuous":[114],"ambulatory":[115],"peritoneal":[116],"(CAPD)":[118],"who":[119],"carried":[120],"had":[123],"a":[124,140],"20-year":[125],"history":[126],"sensory":[128],"hearing":[129],"loss":[130],"as":[131,133],"well":[132],"hypertrophic":[134],"cardiomyopathy.":[135],"CONCLUSION:":[136],"found":[138,163],"that":[139],"gene":[142],"present":[148],"one":[150],"NIDDM":[154],"The":[157],"be":[165],"below":[166],"1%":[167],"diabetic":[169],"end-stage":[170],"renal":[171],"disease":[172],"Japan.":[175]},"counts_by_year":[{"year":2022,"cited_by_count":1},{"year":2020,"cited_by_count":3},{"year":2018,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}