{"id":"https://openalex.org/W2129676141","doi":null,"title":"A Two-hour Urinary Protein-creatinine Ratio for Predicting Significant Proteinuria in Preeclampsia","display_name":"A Two-hour Urinary Protein-creatinine Ratio for Predicting Significant Proteinuria in Preeclampsia","publication_year":2009,"publication_date":"2009-12-01","ids":{"openalex":"https://openalex.org/W2129676141","mag":"2129676141"},"language":"en","primary_location":{"id":"pmh:oai:he02.tci-thaijo.org:article/1486","doi":null,"is_oa":true,"landing_page_url":"https://he02.tci-thaijo.org/index.php/tjog/article/view/1486","pdf_url":"https://he02.tci-thaijo.org/index.php/tjog/article/download/1486/1213","source":{"id":"https://openalex.org/S2764520499","display_name":"Thai Journal of Obstetrics and Gynaecology","issn_l":"0857-6084","issn":["0857-6084","2673-0871"],"is_oa":true,"is_in_doaj":true,"is_core":false,"listed_in":["doaj","poland-20","russia-white-list-4"],"host_organization":"https://openalex.org/P4310319374","host_organization_name":"Chiang Mai University","host_organization_lineage":["https://openalex.org/P4310319374"],"host_organization_lineage_names":["Chiang Mai University"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"0857-6084","raw_type":"info:eu-repo/semantics/article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["doaj"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://he02.tci-thaijo.org/index.php/tjog/article/download/1486/1213","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5035113934","display_name":"Supachai Raungkaewmanee","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2800913826","display_name":"Bangkok Metropolitan Administration","ror":"https://ror.org/04g5xjh29","country_code":"TH","type":"government","lineage":["https://openalex.org/I2800913826"]},{"id":"https://openalex.org/I2801262096","display_name":"Vajira Hospital","ror":"https://ror.org/04evmpa20","country_code":"TH","type":"healthcare","lineage":["https://openalex.org/I2801262096"]}],"countries":["TH"],"is_corresponding":false,"raw_author_name":"Supachai Raungkaewmanee","raw_affiliation_strings":["Department of Obstetrics and Gynecology, Bangkok Metropolitan Administration ,#R##N#Medical College and Vajira Hospital, Bangkok"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Obstetrics and Gynecology, Bangkok Metropolitan Administration ,#R##N#Medical College and Vajira Hospital, Bangkok","institution_ids":["https://openalex.org/I2800913826","https://openalex.org/I2801262096"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5069647695","display_name":"Chadakarn Phaloprakarn","orcid":"https://orcid.org/0000-0002-0925-2613","observed_orcids":["https://orcid.org/0000-0002-0925-2613"]},"institutions":[{"id":"https://openalex.org/I2800913826","display_name":"Bangkok Metropolitan Administration","ror":"https://ror.org/04g5xjh29","country_code":"TH","type":"government","lineage":["https://openalex.org/I2800913826"]},{"id":"https://openalex.org/I2801262096","display_name":"Vajira Hospital","ror":"https://ror.org/04evmpa20","country_code":"TH","type":"healthcare","lineage":["https://openalex.org/I2801262096"]}],"countries":["TH"],"is_corresponding":false,"raw_author_name":"Chadakarn Phaloprakarn","raw_affiliation_strings":["Department of Obstetrics and Gynecology, Bangkok Metropolitan Administration ,#R##N#Medical College and Vajira Hospital, Bangkok"],"raw_orcid":"https://orcid.org/0000-0002-0925-2613","affiliations":[{"raw_affiliation_string":"Department of Obstetrics and Gynecology, Bangkok Metropolitan Administration ,#R##N#Medical College and Vajira Hospital, Bangkok","institution_ids":["https://openalex.org/I2800913826","https://openalex.org/I2801262096"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5089881146","display_name":"Sumonmal Manusirivithaya","orcid":"https://orcid.org/0009-0005-3316-1753","observed_orcids":["https://orcid.org/0009-0005-3316-1753"]},"institutions":[{"id":"https://openalex.org/I2800913826","display_name":"Bangkok Metropolitan Administration","ror":"https://ror.org/04g5xjh29","country_code":"TH","type":"government","lineage":["https://openalex.org/I2800913826"]},{"id":"https://openalex.org/I2801262096","display_name":"Vajira Hospital","ror":"https://ror.org/04evmpa20","country_code":"TH","type":"healthcare","lineage":["https://openalex.org/I2801262096"]}],"countries":["TH"],"is_corresponding":false,"raw_author_name":"Sumonmal Manusirivithaya","raw_affiliation_strings":["Department of Obstetrics and Gynecology, Bangkok Metropolitan Administration ,#R##N#Medical College and Vajira Hospital, Bangkok"],"raw_orcid":"https://orcid.org/0009-0005-3316-1753","affiliations":[{"raw_affiliation_string":"Department of Obstetrics and Gynecology, Bangkok Metropolitan Administration ,#R##N#Medical College and Vajira Hospital, Bangkok","institution_ids":["https://openalex.org/I2800913826","https://openalex.org/I2801262096"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5022602910","display_name":"Budsaba Wiriyasirivaj","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2800913826","display_name":"Bangkok Metropolitan Administration","ror":"https://ror.org/04g5xjh29","country_code":"TH","type":"government","lineage":["https://openalex.org/I2800913826"]},{"id":"https://openalex.org/I2801262096","display_name":"Vajira Hospital","ror":"https://ror.org/04evmpa20","country_code":"TH","type":"healthcare","lineage":["https://openalex.org/I2801262096"]}],"countries":["TH"],"is_corresponding":false,"raw_author_name":"Budsaba Wiriyasirivaj","raw_affiliation_strings":["Department of Obstetrics and Gynecology, Bangkok Metropolitan Administration ,#R##N#Medical College and Vajira Hospital, Bangkok"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Obstetrics and Gynecology, Bangkok Metropolitan Administration ,#R##N#Medical College and Vajira Hospital, Bangkok","institution_ids":["https://openalex.org/I2800913826","https://openalex.org/I2801262096"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":100,"currency":"USD","value_usd":100},"apc_paid":{"value":100,"currency":"USD","value_usd":100},"fwci":0.0,"has_fulltext":true,"cited_by_count":7,"citation_normalized_percentile":{"value":0.32616533,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":96},"biblio":{"volume":"17","issue":"4","first_page":"196","last_page":"203"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10290","display_name":"Pregnancy and preeclampsia studies","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2729","display_name":"Obstetrics and Gynecology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10290","display_name":"Pregnancy and preeclampsia studies","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2729","display_name":"Obstetrics and Gynecology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12464","display_name":"Neurological Complications and Syndromes","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Clinical Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11314","display_name":"Clinical Laboratory Practices and Quality Control","score":0.0,"subfield":{"id":"https://openalex.org/subfields/3607","display_name":"Medical Laboratory Technology"},"field":{"id":"https://openalex.org/fields/36","display_name":"Health Professions"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/preeclampsia","display_name":"preeclampsia","score":0.9610000252723694},{"id":"https://openalex.org/keywords/urine-protein-creatinine-ratio","display_name":"urine protein-to-creatinine ratio","score":0.9399999976158142},{"id":"https://openalex.org/keywords/proteinuria","display_name":"proteinuria","score":0.8389999866485596},{"id":"https://openalex.org/keywords/24-hour-urinary-protein","display_name":"24-hour urine protein","score":0.8489999771118164},{"id":"https://openalex.org/keywords/cutoff-values","display_name":"cut-off values","score":0.6700000166893005},{"id":"https://openalex.org/keywords/diagnostic-accuracy","display_name":"diagnostic accuracy","score":0.8190000057220459},{"id":"https://openalex.org/keywords/pregnancy","display_name":"pregnancy","score":0.4020000100135803}],"concepts":[{"id":"https://openalex.org/C2779561371","wikidata":"https://www.wikidata.org/wiki/Q570197","display_name":"Proteinuria","level":3,"score":0.8913849592208862},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8357671499252319},{"id":"https://openalex.org/C2780026642","wikidata":"https://www.wikidata.org/wiki/Q40924","display_name":"Urine","level":2,"score":0.7521038055419922},{"id":"https://openalex.org/C2777218350","wikidata":"https://www.wikidata.org/wiki/Q61335","display_name":"Preeclampsia","level":3,"score":0.7329177260398865},{"id":"https://openalex.org/C2780306776","wikidata":"https://www.wikidata.org/wiki/Q426660","display_name":"Creatinine","level":2,"score":0.6885808706283569},{"id":"https://openalex.org/C58471807","wikidata":"https://www.wikidata.org/wiki/Q327120","display_name":"Receiver operating characteristic","level":2,"score":0.6634417772293091},{"id":"https://openalex.org/C2778217198","wikidata":"https://www.wikidata.org/wiki/Q556977","display_name":"Cutoff","level":2,"score":0.6291457414627075},{"id":"https://openalex.org/C77411442","wikidata":"https://www.wikidata.org/wiki/Q181100","display_name":"Urinary system","level":2,"score":0.6087017059326172},{"id":"https://openalex.org/C126894567","wikidata":"https://www.wikidata.org/wiki/Q105650","display_name":"Urology","level":1,"score":0.570362389087677},{"id":"https://openalex.org/C76318530","wikidata":"https://www.wikidata.org/wiki/Q16833590","display_name":"Area under the curve","level":2,"score":0.44186750054359436},{"id":"https://openalex.org/C159641895","wikidata":"https://www.wikidata.org/wiki/Q108377937","display_name":"Renal function","level":2,"score":0.41392961144447327},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.3628776967525482},{"id":"https://openalex.org/C2779234561","wikidata":"https://www.wikidata.org/wiki/Q11995","display_name":"Pregnancy","level":2,"score":0.29535335302352905},{"id":"https://openalex.org/C2780091579","wikidata":"https://www.wikidata.org/wiki/Q9377","display_name":"Kidney","level":2,"score":0.09272825717926025},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.053683340549468994},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.0},{"id":"https://openalex.org/C62520636","wikidata":"https://www.wikidata.org/wiki/Q944","display_name":"Quantum mechanics","level":1,"score":0.0}],"mesh":[],"locations_count":3,"locations":[{"id":"pmh:oai:he02.tci-thaijo.org:article/1486","doi":null,"is_oa":true,"landing_page_url":"https://he02.tci-thaijo.org/index.php/tjog/article/view/1486","pdf_url":"https://he02.tci-thaijo.org/index.php/tjog/article/download/1486/1213","source":{"id":"https://openalex.org/S2764520499","display_name":"Thai Journal of Obstetrics and Gynaecology","issn_l":"0857-6084","issn":["0857-6084","2673-0871"],"is_oa":true,"is_in_doaj":true,"is_core":false,"listed_in":["doaj","poland-20","russia-white-list-4"],"host_organization":"https://openalex.org/P4310319374","host_organization_name":"Chiang Mai University","host_organization_lineage":["https://openalex.org/P4310319374"],"host_organization_lineage_names":["Chiang Mai University"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"0857-6084","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:doaj.org/article:d76646a7e108473bb0ea08af404af959","doi":null,"is_oa":false,"landing_page_url":"https://doaj.org/article/d76646a7e108473bb0ea08af404af959","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Thai Journal of Obstetrics and Gynaecology, Vol 17, Iss 4, Pp 196-203 (2009)","raw_type":"article"},{"id":"mag:2129676141","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/d76646a7e108473bb0ea08af404af959","pdf_url":null,"source":{"id":"https://openalex.org/S2764520499","display_name":"Thai Journal of Obstetrics and Gynaecology","issn_l":"0857-6084","issn":["0857-6084","2673-0871"],"is_oa":true,"is_in_doaj":true,"is_core":false,"listed_in":["doaj","poland-20","russia-white-list-4"],"host_organization":"https://openalex.org/P4310319374","host_organization_name":"Chiang Mai University","host_organization_lineage":["https://openalex.org/P4310319374"],"host_organization_lineage_names":["Chiang Mai University"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":null,"is_accepted":false,"is_published":false,"raw_source_name":"Thai Journal of Obstetrics and Gynaecology","raw_type":null}],"best_oa_location":{"id":"pmh:oai:he02.tci-thaijo.org:article/1486","doi":null,"is_oa":true,"landing_page_url":"https://he02.tci-thaijo.org/index.php/tjog/article/view/1486","pdf_url":"https://he02.tci-thaijo.org/index.php/tjog/article/download/1486/1213","source":{"id":"https://openalex.org/S2764520499","display_name":"Thai Journal of Obstetrics and Gynaecology","issn_l":"0857-6084","issn":["0857-6084","2673-0871"],"is_oa":true,"is_in_doaj":true,"is_core":false,"listed_in":["doaj","poland-20","russia-white-list-4"],"host_organization":"https://openalex.org/P4310319374","host_organization_name":"Chiang Mai University","host_organization_lineage":["https://openalex.org/P4310319374"],"host_organization_lineage_names":["Chiang Mai University"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"0857-6084","raw_type":"info:eu-repo/semantics/article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.9940000176429749}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2129676141.pdf","grobid_xml":"https://content.openalex.org/works/W2129676141.grobid-xml"},"referenced_works_count":18,"referenced_works":["https://openalex.org/W160658781","https://openalex.org/W1979119639","https://openalex.org/W1993285586","https://openalex.org/W2011950522","https://openalex.org/W2013065041","https://openalex.org/W2031764741","https://openalex.org/W2036477553","https://openalex.org/W2065011085","https://openalex.org/W2069291368","https://openalex.org/W2078709831","https://openalex.org/W2084574564","https://openalex.org/W2134659217","https://openalex.org/W2156490188","https://openalex.org/W2185100017","https://openalex.org/W2323304773","https://openalex.org/W2499195416","https://openalex.org/W3160565403","https://openalex.org/W3203440974"],"related_works":["https://openalex.org/W4405407546","https://openalex.org/W1968416042","https://openalex.org/W2025312056","https://openalex.org/W2800329482","https://openalex.org/W2123938116","https://openalex.org/W1979119639","https://openalex.org/W2437379085","https://openalex.org/W2269944679","https://openalex.org/W2084574564","https://openalex.org/W2625860905"],"abstract_inverted_index":{"Objective:":[0],"To":[1],"determine":[2,126],"an":[3],"optimal":[4,128,174],"cutoff":[5,129,175,209,221],"level":[6,130,176,210,222],"of":[7,55,116,135,140,143,196,211,217,223],"urinary":[8,102,119,171,232],"protein-creatinine":[9],"ratio":[10],"(PCR)":[11],"obtaining":[12],"from":[13,18],"2":[14,76],"hours":[15,77,86],"urine":[16,67,78,87,161,165],"collection":[17],"women":[19,34,145],"admitted":[20,43],"with":[21,35],"suspected":[22],"preeclampsia":[23,56],"for":[24,53,73,82,93,131],"predicting":[25],"significant":[26,152,179,241],"proteinuria.":[27,136,153],"Study":[28],"design:":[29],"Diagnostic":[30],"test.":[31],"Subject:":[32],"Pregnant":[33],"gestational":[36],"age":[37],">":[38],"20":[39],"weeks":[40],"who":[41],"were":[42,57,61,108],"at":[44],"Bangkok":[45],"Metropolitan":[46],"Administration":[47],"Medical":[48],"College":[49],"and":[50,79,96,104,163,190,201],"Vajira":[51],"Hospital":[52],"evaluation":[54],"studied":[58],"prospectively.":[59],"They":[60],"instructed":[62],"to":[63,125,177,239,244],"collect":[64],"a":[65,169,208,215,236],"24-hour":[66,106,164],"in":[68,123],"two":[69],"separate":[70],"containers:":[71],"one":[72],"the":[74,80,83,117,127,133,147,173,193,205,220],"first":[75,100],"other":[81,206],"following":[84],"22":[85],"specimens.":[88],"Each":[89],"sample":[90],"was":[91,121,181],"measured":[92],"volume,":[94],"protein,":[95],"creatinine":[97],"values.":[98],"The":[99,230],"2-hour":[101,118,160,170,231],"PCR":[103,120,233],"total":[105,139],"proteinuria":[107,180,242],"calculated.":[109],"A":[110,138],"receiver":[111],"operating":[112],"characteristic":[113],"curve":[114,195],"(ROC)":[115],"constructed":[122],"order":[124],"estimate":[132],"degree":[134],"Results:":[137],"182":[141],"out":[142],"187":[144],"completed":[146],"study;":[148],"137":[149],"(75%)":[150],"had":[151,214],"This":[154],"study":[155],"demonstrated":[156],"moderate":[157],"correlation":[158],"between":[159],"protein":[162],"protein(r=0.451).":[166],"By":[167],"using":[168],"PCR,":[172],"predict":[178,240],"\u2265":[182,212,224],"0.30":[183],"which":[184],"yielded":[185],"sensitivity,":[186],"specificity,":[187],"PPV,":[188],"NPV":[189],"area":[191],"under":[192],"ROC":[194],"71.5%,":[197],"71.1%,":[198],"88.3%,":[199],"45.1%":[200],"0.801":[202],"respectively.":[203],"On":[204],"hand,":[207],"0.05":[213],"sensitivity":[216],"100%,":[218],"while":[219],"2.0":[225],"offered":[226],"100%":[227],"specificity.":[228],"Conclusions:":[229],"is":[234],"not":[235],"good":[237],"test":[238],"due":[243],"its":[245],"high":[246],"false":[247],"negative":[248],"rate.":[249]},"counts_by_year":[{"year":2020,"cited_by_count":1},{"year":2016,"cited_by_count":2},{"year":2014,"cited_by_count":2},{"year":2013,"cited_by_count":2}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}