{"id":"https://openalex.org/W2129573571","doi":"https://doi.org/10.1021/bi0359325","title":"Conformational Change of the Dimeric DsbC Molecule Induced by GdnHCl. A Study by Intrinsic Fluorescence","display_name":"Conformational Change of the Dimeric DsbC Molecule Induced by GdnHCl. A Study by Intrinsic Fluorescence","publication_year":2004,"publication_date":"2004-04-10","ids":{"openalex":"https://openalex.org/W2129573571","doi":"https://doi.org/10.1021/bi0359325","mag":"2129573571","pmid":"https://pubmed.ncbi.nlm.nih.gov/15122895"},"language":"en","primary_location":{"id":"doi:10.1021/bi0359325","doi":"https://doi.org/10.1021/bi0359325","is_oa":false,"landing_page_url":"https://doi.org/10.1021/bi0359325","pdf_url":null,"source":{"id":"https://openalex.org/S104038378","display_name":"Biochemistry","issn_l":"0006-2960","issn":["0006-2960","1520-4995","1943-295X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320006","host_organization_name":"American Chemical Society","host_organization_lineage":["https://openalex.org/P4310320006"],"host_organization_lineage_names":["American Chemical Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biochemistry","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5056211468","display_name":"Olga V. Stepanenko","orcid":"https://orcid.org/0000-0002-9145-3480","observed_orcids":["https://orcid.org/0000-0002-9145-3480"]},"institutions":[{"id":"https://openalex.org/I19820366","display_name":"Chinese Academy of Sciences","ror":"https://ror.org/034t30j35","country_code":"CN","type":"government","lineage":["https://openalex.org/I19820366"]},{"id":"https://openalex.org/I4210104940","display_name":"Institute of Cytology","ror":"https://ror.org/01p3q4q56","country_code":"RU","type":"facility","lineage":["https://openalex.org/I1313323035","https://openalex.org/I4210104940","https://openalex.org/I4210129690"]},{"id":"https://openalex.org/I4210112540","display_name":"Institute of Biophysics","ror":"https://ror.org/01tyv8576","country_code":"CN","type":"facility","lineage":["https://openalex.org/I19820366","https://openalex.org/I4210112540"]}],"countries":["CN","RU"],"is_corresponding":false,"raw_author_name":"Olga V. Stepanenko","raw_affiliation_strings":["Institute of Cytology, Russian Academy of Science, Tihkoretsky av. 4, St. Petersburg 194064, Russia, and National Laboratory of Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, 15 Datun Road, Beijing 100101, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Cytology, Russian Academy of Science, Tihkoretsky av. 4, St. Petersburg 194064, Russia, and National Laboratory of Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, 15 Datun Road, Beijing 100101, China","institution_ids":["https://openalex.org/I19820366","https://openalex.org/I4210104940","https://openalex.org/I4210112540"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5061683155","display_name":"Irina \u041c. Kuznetsova","orcid":"https://orcid.org/0000-0002-3336-4834","observed_orcids":["https://orcid.org/0000-0002-3336-4834"]},"institutions":[{"id":"https://openalex.org/I19820366","display_name":"Chinese Academy of Sciences","ror":"https://ror.org/034t30j35","country_code":"CN","type":"government","lineage":["https://openalex.org/I19820366"]},{"id":"https://openalex.org/I4210104940","display_name":"Institute of Cytology","ror":"https://ror.org/01p3q4q56","country_code":"RU","type":"facility","lineage":["https://openalex.org/I1313323035","https://openalex.org/I4210104940","https://openalex.org/I4210129690"]},{"id":"https://openalex.org/I4210112540","display_name":"Institute of Biophysics","ror":"https://ror.org/01tyv8576","country_code":"CN","type":"facility","lineage":["https://openalex.org/I19820366","https://openalex.org/I4210112540"]}],"countries":["CN","RU"],"is_corresponding":false,"raw_author_name":"Irina M. Kuznetsova","raw_affiliation_strings":["Institute of Cytology, Russian Academy of Science, Tihkoretsky av. 4, St. Petersburg 194064, Russia, and National Laboratory of Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, 15 Datun Road, Beijing 100101, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Cytology, Russian Academy of Science, Tihkoretsky av. 4, St. Petersburg 194064, Russia, and National Laboratory of Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, 15 Datun Road, Beijing 100101, China","institution_ids":["https://openalex.org/I19820366","https://openalex.org/I4210104940","https://openalex.org/I4210112540"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5007445606","display_name":"\u0422\u0443\u0440\u043e\u0432\u0435\u0440\u043e\u0432 \u041a\u043e\u043d\u0441\u0442\u0430\u043d\u0442\u0438\u043d \u041a\u043e\u043d\u0441\u0442\u0430\u043d\u0442\u0438\u043d\u043e\u0432\u0438\u0447","orcid":"https://orcid.org/0000-0002-6977-1896","observed_orcids":["https://orcid.org/0000-0002-6977-1896","https://orcid.org/0000-0002-3336-4834"]},"institutions":[{"id":"https://openalex.org/I19820366","display_name":"Chinese Academy of Sciences","ror":"https://ror.org/034t30j35","country_code":"CN","type":"government","lineage":["https://openalex.org/I19820366"]},{"id":"https://openalex.org/I4210104940","display_name":"Institute of Cytology","ror":"https://ror.org/01p3q4q56","country_code":"RU","type":"facility","lineage":["https://openalex.org/I1313323035","https://openalex.org/I4210104940","https://openalex.org/I4210129690"]},{"id":"https://openalex.org/I4210112540","display_name":"Institute of Biophysics","ror":"https://ror.org/01tyv8576","country_code":"CN","type":"facility","lineage":["https://openalex.org/I19820366","https://openalex.org/I4210112540"]}],"countries":["CN","RU"],"is_corresponding":false,"raw_author_name":"Konstantin K. Turoverov","raw_affiliation_strings":["Institute of Cytology, Russian Academy of Science, Tihkoretsky av. 4, St. Petersburg 194064, Russia, and National Laboratory of Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, 15 Datun Road, Beijing 100101, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Cytology, Russian Academy of Science, Tihkoretsky av. 4, St. Petersburg 194064, Russia, and National Laboratory of Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, 15 Datun Road, Beijing 100101, China","institution_ids":["https://openalex.org/I19820366","https://openalex.org/I4210104940","https://openalex.org/I4210112540"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110200340","display_name":"Chunjuan Huang","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I19820366","display_name":"Chinese Academy of Sciences","ror":"https://ror.org/034t30j35","country_code":"CN","type":"government","lineage":["https://openalex.org/I19820366"]},{"id":"https://openalex.org/I4210104940","display_name":"Institute of Cytology","ror":"https://ror.org/01p3q4q56","country_code":"RU","type":"facility","lineage":["https://openalex.org/I1313323035","https://openalex.org/I4210104940","https://openalex.org/I4210129690"]},{"id":"https://openalex.org/I4210112540","display_name":"Institute of Biophysics","ror":"https://ror.org/01tyv8576","country_code":"CN","type":"facility","lineage":["https://openalex.org/I19820366","https://openalex.org/I4210112540"]}],"countries":["CN","RU"],"is_corresponding":false,"raw_author_name":"Chunjuan Huang","raw_affiliation_strings":["Institute of Cytology, Russian Academy of Science, Tihkoretsky av. 4, St. Petersburg 194064, Russia, and National Laboratory of Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, 15 Datun Road, Beijing 100101, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Cytology, Russian Academy of Science, Tihkoretsky av. 4, St. Petersburg 194064, Russia, and National Laboratory of Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, 15 Datun Road, Beijing 100101, China","institution_ids":["https://openalex.org/I19820366","https://openalex.org/I4210104940","https://openalex.org/I4210112540"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5084163607","display_name":"Chih-chen Wang","orcid":"https://orcid.org/0009-0002-6734-8573","observed_orcids":["https://orcid.org/0009-0002-6734-8573","https://orcid.org/0009-0008-1949-3024"]},"institutions":[{"id":"https://openalex.org/I19820366","display_name":"Chinese Academy of Sciences","ror":"https://ror.org/034t30j35","country_code":"CN","type":"government","lineage":["https://openalex.org/I19820366"]},{"id":"https://openalex.org/I4210104940","display_name":"Institute of Cytology","ror":"https://ror.org/01p3q4q56","country_code":"RU","type":"facility","lineage":["https://openalex.org/I1313323035","https://openalex.org/I4210104940","https://openalex.org/I4210129690"]},{"id":"https://openalex.org/I4210112540","display_name":"Institute of Biophysics","ror":"https://ror.org/01tyv8576","country_code":"CN","type":"facility","lineage":["https://openalex.org/I19820366","https://openalex.org/I4210112540"]}],"countries":["CN","RU"],"is_corresponding":false,"raw_author_name":"Chih-chen Wang","raw_affiliation_strings":["Institute of Cytology, Russian Academy of Science, Tihkoretsky av. 4, St. Petersburg 194064, Russia, and National Laboratory of Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, 15 Datun Road, Beijing 100101, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Cytology, Russian Academy of Science, Tihkoretsky av. 4, St. Petersburg 194064, Russia, and National Laboratory of Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, 15 Datun Road, Beijing 100101, China","institution_ids":["https://openalex.org/I19820366","https://openalex.org/I4210104940","https://openalex.org/I4210112540"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":3,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":4500,"currency":"USD","value_usd":4500},"apc_paid":null,"fwci":0.2923,"has_fulltext":false,"cited_by_count":21,"citation_normalized_percentile":{"value":0.45337902,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":98},"biblio":{"volume":"43","issue":"18","first_page":"5296","last_page":"5303"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10044","display_name":"Protein Structure and Dynamics","score":0.9907000064849854,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10044","display_name":"Protein Structure and Dynamics","score":0.9907000064849854,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11162","display_name":"Enzyme Structure and Function","score":0.002300000051036477,"subfield":{"id":"https://openalex.org/subfields/1315","display_name":"Structural Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11124","display_name":"Protein purification and stability","score":0.001500000013038516,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/dsbc","display_name":"DsbC","score":0.9950000047683716},{"id":"https://openalex.org/keywords/disulfide-bond-formation","display_name":"disulfide bond formation","score":0.6949999928474426},{"id":"https://openalex.org/keywords/homodimer","display_name":"homodimer","score":0.8360000252723694},{"id":"https://openalex.org/keywords/urea-induced-unfolding","display_name":"urea-induced unfolding","score":0.8169999718666077},{"id":"https://openalex.org/keywords/protein-denaturation","display_name":"protein denaturation","score":0.7099999785423279},{"id":"https://openalex.org/keywords/intrinsic-fluorescence","display_name":"intrinsic fluorescence","score":0.675000011920929},{"id":"https://openalex.org/keywords/tryptophan-fluorescence-quenching","display_name":"tryptophan fluorescence quenching","score":0.9110000133514404},{"id":"https://openalex.org/keywords/tyrosine-fluorescence","display_name":"tyrosine fluorescence","score":0.781000018119812},{"id":"https://openalex.org/keywords/isosbestic-point","display_name":"isosbestic point","score":0.8679999709129333},{"id":"https://openalex.org/keywords/unfolding-kinetics","display_name":"unfolding kinetics","score":0.5339999794960022},{"id":"https://openalex.org/keywords/escherichia-coli","display_name":"Escherichia coli","score":0.8510000109672546}],"concepts":[{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.8078864216804504},{"id":"https://openalex.org/C91881484","wikidata":"https://www.wikidata.org/wiki/Q191807","display_name":"Fluorescence","level":2,"score":0.7028671503067017},{"id":"https://openalex.org/C2776706248","wikidata":"https://www.wikidata.org/wiki/Q181003","display_name":"Tryptophan","level":3,"score":0.6182126998901367},{"id":"https://openalex.org/C2776923230","wikidata":"https://www.wikidata.org/wiki/Q16955798","display_name":"Denaturation (fissile materials)","level":2,"score":0.5208737850189209},{"id":"https://openalex.org/C175188612","wikidata":"https://www.wikidata.org/wiki/Q5384491","display_name":"Equilibrium unfolding","level":3,"score":0.5104864835739136},{"id":"https://openalex.org/C2776165026","wikidata":"https://www.wikidata.org/wiki/Q188017","display_name":"Tyrosine","level":2,"score":0.4698304831981659},{"id":"https://openalex.org/C32909587","wikidata":"https://www.wikidata.org/wiki/Q11369","display_name":"Molecule","level":2,"score":0.46134617924690247},{"id":"https://openalex.org/C192527728","wikidata":"https://www.wikidata.org/wiki/Q1465700","display_name":"Indole test","level":2,"score":0.42241063714027405},{"id":"https://openalex.org/C8010536","wikidata":"https://www.wikidata.org/wiki/Q160398","display_name":"Crystallography","level":1,"score":0.4188064932823181},{"id":"https://openalex.org/C71240020","wikidata":"https://www.wikidata.org/wiki/Q186011","display_name":"Stereochemistry","level":1,"score":0.276563823223114},{"id":"https://openalex.org/C133571119","wikidata":"https://www.wikidata.org/wiki/Q899102","display_name":"Circular dichroism","level":2,"score":0.20262184739112854},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.1419563591480255},{"id":"https://openalex.org/C515207424","wikidata":"https://www.wikidata.org/wiki/Q8066","display_name":"Amino acid","level":2,"score":0.07681384682655334},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.07293587923049927},{"id":"https://openalex.org/C13965031","wikidata":"https://www.wikidata.org/wiki/Q243545","display_name":"Nuclear chemistry","level":1,"score":0.0},{"id":"https://openalex.org/C62520636","wikidata":"https://www.wikidata.org/wiki/Q944","display_name":"Quantum mechanics","level":1,"score":0.0},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D007700","descriptor_name":"Kinetics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008956","descriptor_name":"Models, Chemical","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008958","descriptor_name":"Models, Molecular","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011487","descriptor_name":"Protein Conformation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011489","descriptor_name":"Protein Denaturation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013050","descriptor_name":"Spectrometry, Fluorescence","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D014364","descriptor_name":"Tryptophan","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D014443","descriptor_name":"Tyrosine","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D017510","descriptor_name":"Protein Folding","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019281","descriptor_name":"Dimerization","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019704","descriptor_name":"Protein Disulfide-Isomerases","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D019791","descriptor_name":"Guanidine","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D029968","descriptor_name":"Escherichia coli Proteins","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true}],"locations_count":3,"locations":[{"id":"doi:10.1021/bi0359325","doi":"https://doi.org/10.1021/bi0359325","is_oa":false,"landing_page_url":"https://doi.org/10.1021/bi0359325","pdf_url":null,"source":{"id":"https://openalex.org/S104038378","display_name":"Biochemistry","issn_l":"0006-2960","issn":["0006-2960","1520-4995","1943-295X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320006","host_organization_name":"American Chemical Society","host_organization_lineage":["https://openalex.org/P4310320006"],"host_organization_lineage_names":["American Chemical Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biochemistry","raw_type":"journal-article"},{"id":"pmid:15122895","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/15122895","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biochemistry","raw_type":"Journal Article"},{"id":"pmh:oai:CiteSeerX.psu:10.1.1.655.2331","doi":null,"is_oa":false,"landing_page_url":"http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.655.2331","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"http://library.ibp.ac.cn/html/slwj/000221343200019.pdf","raw_type":"text"}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":33,"referenced_works":["https://openalex.org/W83884975","https://openalex.org/W1522290718","https://openalex.org/W1788190869","https://openalex.org/W1830036395","https://openalex.org/W1963994022","https://openalex.org/W1966041739","https://openalex.org/W1969300977","https://openalex.org/W1977294234","https://openalex.org/W1980597219","https://openalex.org/W1990898399","https://openalex.org/W1994645861","https://openalex.org/W2021024369","https://openalex.org/W2029667189","https://openalex.org/W2041377302","https://openalex.org/W2045787232","https://openalex.org/W2053349920","https://openalex.org/W2060837765","https://openalex.org/W2078259224","https://openalex.org/W2078528113","https://openalex.org/W2080528351","https://openalex.org/W2080970333","https://openalex.org/W2082735691","https://openalex.org/W2084808709","https://openalex.org/W2088279705","https://openalex.org/W2096601751","https://openalex.org/W2152229434","https://openalex.org/W2163350887","https://openalex.org/W2167080260","https://openalex.org/W2169505354","https://openalex.org/W2327477270","https://openalex.org/W2400029927","https://openalex.org/W2795480261","https://openalex.org/W4285719527"],"related_works":["https://openalex.org/W7097183843","https://openalex.org/W2143883187","https://openalex.org/W2052360478","https://openalex.org/W2065788701","https://openalex.org/W2403238492","https://openalex.org/W1986648910","https://openalex.org/W2365905259","https://openalex.org/W2100568138","https://openalex.org/W1998384753","https://openalex.org/W2165456161"],"abstract_inverted_index":{"Unfolding-refolding":[0],"of":[1,17,27,42,52,88,110,115,133,137,149],"Escherichia":[2],"coli":[3],"DsbC,":[4],"a":[5,146],"homodimeric":[6],"molecule,":[7],"induced":[8,120],"by":[9,13,121],"GdnHCl":[10,122,142],"was":[11,21,82],"studied":[12],"intrinsic":[14,116],"fluorescence.":[15],"Interpretation":[16],"experimental":[18],"fluorescence":[19,109,117,138],"data":[20],"done":[22],"together":[23],"with":[24],"the":[25,39,43,49,53,63,72,107,111,131],"analysis":[26],"protein":[28],"3D":[29],"structure.":[30],"It":[31,81],"is":[32,38],"shown":[33],"that":[34,84],"although":[35],"Cys":[36,56],"141":[37],"next":[40],"neighbor":[41],"single":[44],"tryptophan":[45],"residue":[46],"(Trp":[47],"140),":[48],"sulfur":[50],"atoms":[51],"disulfide":[54],"bond":[55],"141-Cys":[57],"163":[58],"are":[59,75],"far":[60],"apart":[61],"from":[62],"indole":[64],"ring":[65],"and":[66,78,102,124,127,152],"cannot":[67],"quench":[68],"its":[69,128,153],"fluorescence,":[70],"while":[71],"potential":[73],"quenchers":[74],"Met":[76],"136":[77],"His":[79],"170.":[80],"revealed":[83],"though":[85],"each":[86],"subunit":[87],"DsbC":[89,150],"contains":[90],"eight":[91],"tyrosine":[92,96],"residues,":[93],"only":[94],"three":[95],"residues":[97],"(Tyr":[98],"171,":[99],"Tyr":[100,103],"38,":[101],"52)":[104],"contribute":[105],"to":[106],"bulk":[108],"molecule.":[112],"The":[113],"character":[114,148],"intensity":[118],"changes":[119],"(equilibrium":[123],"kinetic":[125],"data)":[126],"parametric":[129],"representation,":[130],"existence":[132],"an":[134],"isosbestic":[135],"point":[136],"spectra":[139],"at":[140],"different":[141],"concentrations,":[143],"allowed":[144],"suggesting":[145],"one-step":[147],"denaturation":[151],"reversibility.":[154]},"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2021,"cited_by_count":3},{"year":2018,"cited_by_count":1},{"year":2016,"cited_by_count":6},{"year":2014,"cited_by_count":3},{"year":2012,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}