{"id":"https://openalex.org/W2129558341","doi":"https://doi.org/10.1371/journal.pone.0060397","title":"Study of Global Transcriptional Changes of N-GlcNAc2 Proteins-Producing T24 Bladder Carcinoma Cells under Glucose Deprivation","display_name":"Study of Global Transcriptional Changes of N-GlcNAc2 Proteins-Producing T24 Bladder Carcinoma Cells under Glucose Deprivation","publication_year":2013,"publication_date":"2013-04-01","ids":{"openalex":"https://openalex.org/W2129558341","doi":"https://doi.org/10.1371/journal.pone.0060397","mag":"2129558341","pmid":"https://pubmed.ncbi.nlm.nih.gov/23560094","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/3613393"},"language":"en","primary_location":{"id":"doi:10.1371/journal.pone.0060397","doi":"https://doi.org/10.1371/journal.pone.0060397","is_oa":true,"landing_page_url":"https://doi.org/10.1371/journal.pone.0060397","pdf_url":"https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0060397&type=printable","source":{"id":"https://openalex.org/S202381698","display_name":"PLoS ONE","issn_l":"1932-6203","issn":["1932-6203"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","doaj","dongbi-c","doyens","erih-plus","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315706","host_organization_name":"Public Library of Science","host_organization_lineage":["https://openalex.org/P4310315706"],"host_organization_lineage_names":["Public Library of Science"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLoS ONE","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0060397&type=printable","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5047358065","display_name":"Takahiro Isono","orcid":"https://orcid.org/0000-0003-2383-0667","observed_orcids":["https://orcid.org/0000-0003-2383-0667"]},"institutions":[{"id":"https://openalex.org/I160046202","display_name":"Shiga University of Medical Science","ror":"https://ror.org/00d8gp927","country_code":"JP","type":"education","lineage":["https://openalex.org/I160046202"]}],"countries":["JP"],"is_corresponding":true,"raw_author_name":"Takahiro Isono","raw_affiliation_strings":["Central Reseach Laboratory, Shiga University of Medical Science, Otsu, Shiga, Japan. isono@belle.shiga-med.ac.jp","Central Reseach Laboratory, Shiga University of Medical Science, Otsu, Shiga, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Central Reseach Laboratory, Shiga University of Medical Science, Otsu, Shiga, Japan. isono@belle.shiga-med.ac.jp","institution_ids":["https://openalex.org/I160046202"]},{"raw_affiliation_string":"Central Reseach Laboratory, Shiga University of Medical Science, Otsu, Shiga, Japan","institution_ids":["https://openalex.org/I160046202"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5008951043","display_name":"Tokuhiro Chano","orcid":"https://orcid.org/0000-0002-9959-1183","observed_orcids":["https://orcid.org/0000-0002-9959-1183"]},"institutions":[{"id":"https://openalex.org/I160046202","display_name":"Shiga University of Medical Science","ror":"https://ror.org/00d8gp927","country_code":"JP","type":"education","lineage":["https://openalex.org/I160046202"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Tokuhiro Chano","raw_affiliation_strings":["Departments of Clinical Laboratory Medicine, Shiga University of Medical Science, Otsu, Shiga, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departments of Clinical Laboratory Medicine, Shiga University of Medical Science, Otsu, Shiga, Japan","institution_ids":["https://openalex.org/I160046202"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112639110","display_name":"Hidetoshi Okabe","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I160046202","display_name":"Shiga University of Medical Science","ror":"https://ror.org/00d8gp927","country_code":"JP","type":"education","lineage":["https://openalex.org/I160046202"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Hidetoshi Okabe","raw_affiliation_strings":["Departments of Clinical Laboratory Medicine, Shiga University of Medical Science, Otsu, Shiga, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departments of Clinical Laboratory Medicine, Shiga University of Medical Science, Otsu, Shiga, Japan","institution_ids":["https://openalex.org/I160046202"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5110113731","display_name":"Masafumi Suzaki","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I160046202","display_name":"Shiga University of Medical Science","ror":"https://ror.org/00d8gp927","country_code":"JP","type":"education","lineage":["https://openalex.org/I160046202"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Masafumi Suzaki","raw_affiliation_strings":["Central Reseach Laboratory, Shiga University of Medical Science, Otsu, Shiga, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Central Reseach Laboratory, Shiga University of Medical Science, Otsu, Shiga, Japan","institution_ids":["https://openalex.org/I160046202"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5047358065"],"corresponding_institution_ids":["https://openalex.org/I160046202"],"apc_list":{"value":2382,"currency":"USD","value_usd":2382},"apc_paid":{"value":2382,"currency":"USD","value_usd":2382},"fwci":0.6597,"has_fulltext":true,"cited_by_count":13,"citation_normalized_percentile":{"value":0.63272994,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":87,"max":97},"biblio":{"volume":"8","issue":"4","first_page":"e60397","last_page":"e60397"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10602","display_name":"Glycosylation and Glycoproteins Research","score":0.9028000235557556,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10602","display_name":"Glycosylation and Glycoproteins Research","score":0.9028000235557556,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11150","display_name":"Endoplasmic Reticulum Stress and Disease","score":0.07599999755620956,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10631","display_name":"Cancer, Hypoxia, and Metabolism","score":0.00419999985024333,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/glucose-deprivation","display_name":"glucose deprivation","score":0.9580000042915344},{"id":"https://openalex.org/keywords/t24-cells","display_name":"T24 cells","score":0.9490000009536743},{"id":"https://openalex.org/keywords/unfolded-protein-response","display_name":"unfolded protein response","score":0.8080000281333923},{"id":"https://openalex.org/keywords/udp-glcnac-biosynthesis","display_name":"UDP-GlcNAc biosynthesis","score":0.8529999852180481},{"id":"https://openalex.org/keywords/g2-m-cell-cycle-arrest","display_name":"G2/M cell cycle arrest","score":0.8560000061988831},{"id":"https://openalex.org/keywords/mitotic-kinases","display_name":"mitotic kinases","score":0.9559999704360962},{"id":"https://openalex.org/keywords/bip","display_name":"BiP","score":0.8870000243186951},{"id":"https://openalex.org/keywords/endoplasmic-reticulum","display_name":"endoplasmic reticulum","score":0.9120000004768372},{"id":"https://openalex.org/keywords/transcriptome","display_name":"transcriptome","score":0.7089999914169312},{"id":"https://openalex.org/keywords/cell-cycle-regulation","display_name":"cell cycle regulation","score":0.3370000123977661}],"concepts":[{"id":"https://openalex.org/C173396325","wikidata":"https://www.wikidata.org/wiki/Q1501275","display_name":"Gene knockdown","level":3,"score":0.7900523543357849},{"id":"https://openalex.org/C162317418","wikidata":"https://www.wikidata.org/wiki/Q252857","display_name":"Transcriptome","level":4,"score":0.6398947238922119},{"id":"https://openalex.org/C93304396","wikidata":"https://www.wikidata.org/wiki/Q14763008","display_name":"Mitosis","level":2,"score":0.5211341977119446},{"id":"https://openalex.org/C184235292","wikidata":"https://www.wikidata.org/wiki/Q421851","display_name":"Kinase","level":2,"score":0.496268093585968},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.4894665479660034},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.4802687168121338},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.45075058937072754},{"id":"https://openalex.org/C153911025","wikidata":"https://www.wikidata.org/wiki/Q7202","display_name":"Molecular biology","level":1,"score":0.35999563336372375},{"id":"https://openalex.org/C150194340","wikidata":"https://www.wikidata.org/wiki/Q26972","display_name":"Gene expression","level":3,"score":0.34832122921943665},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.23662957549095154}],"mesh":[{"descriptor_ui":"D000091342","descriptor_name":"Endoplasmic Reticulum Chaperone BiP","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000117","descriptor_name":"Acetylglucosamine","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D001743","descriptor_name":"Urinary Bladder","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D001743","descriptor_name":"Urinary Bladder","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D001749","descriptor_name":"Urinary Bladder Neoplasms","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D001749","descriptor_name":"Urinary Bladder Neoplasms","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D001749","descriptor_name":"Urinary Bladder Neoplasms","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D002277","descriptor_name":"Carcinoma","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D002277","descriptor_name":"Carcinoma","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D002277","descriptor_name":"Carcinoma","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D004721","descriptor_name":"Endoplasmic Reticulum","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D004721","descriptor_name":"Endoplasmic Reticulum","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D005947","descriptor_name":"Glucose","qualifier_ui":"Q000172","qualifier_name":"deficiency","is_major_topic":true},{"descriptor_ui":"D006360","descriptor_name":"Heat-Shock Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D006360","descriptor_name":"Heat-Shock Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009363","descriptor_name":"Neoplasm Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D009363","descriptor_name":"Neoplasm Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D011494","descriptor_name":"Protein Kinases","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D011494","descriptor_name":"Protein Kinases","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D014158","descriptor_name":"Transcription, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015972","descriptor_name":"Gene Expression Regulation, Neoplastic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D020869","descriptor_name":"Gene Expression Profiling","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D045744","descriptor_name":"Cell Line, Tumor","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D056811","descriptor_name":"Unfolded Protein Response","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D059565","descriptor_name":"G2 Phase Cell Cycle Checkpoints","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false}],"locations_count":7,"locations":[{"id":"doi:10.1371/journal.pone.0060397","doi":"https://doi.org/10.1371/journal.pone.0060397","is_oa":true,"landing_page_url":"https://doi.org/10.1371/journal.pone.0060397","pdf_url":"https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0060397&type=printable","source":{"id":"https://openalex.org/S202381698","display_name":"PLoS ONE","issn_l":"1932-6203","issn":["1932-6203"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","doaj","dongbi-c","doyens","erih-plus","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315706","host_organization_name":"Public Library of Science","host_organization_lineage":["https://openalex.org/P4310315706"],"host_organization_lineage_names":["Public Library of Science"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLoS ONE","raw_type":"journal-article"},{"id":"pmh:oai:europepmc.org:2616453","doi":null,"is_oa":true,"landing_page_url":"http://europepmc.org/articles/PMC3613393","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"","raw_type":"Text"},{"id":"pmid:23560094","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/23560094","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PloS one","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:3613393","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC3613393/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLoS One","raw_type":"Text"},{"id":"pmh:oai:CiteSeerX.psu:10.1.1.798.3867","doi":null,"is_oa":false,"landing_page_url":"http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.798.3867","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"ftp://ftp.ncbi.nlm.nih.gov/pub/pmc/dc/4b/pone.0060397.PMC3613393.pdf","raw_type":"text"},{"id":"pmh:oai:doaj.org/article:6e005975e0484845aa28d86312dd7a55","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/6e005975e0484845aa28d86312dd7a55","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"PLoS ONE, Vol 8, Iss 4, p e60397 (2013)","raw_type":"article"},{"id":"pmh:oai:figshare.com:article/664001","doi":null,"is_oa":true,"landing_page_url":"https://figshare.com/articles/dataset/Study_of_Global_Transcriptional_Changes_of_N_GlcNAc_2_Proteins_Producing_T24_Bladder_Carcinoma_Cells_under_Glucose_Deprivation/664001","pdf_url":null,"source":{"id":"https://openalex.org/S4377196282","display_name":"Figshare","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4210132348","host_organization_name":"Figshare (United Kingdom)","host_organization_lineage":["https://openalex.org/I4210132348"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Dataset"}],"best_oa_location":{"id":"doi:10.1371/journal.pone.0060397","doi":"https://doi.org/10.1371/journal.pone.0060397","is_oa":true,"landing_page_url":"https://doi.org/10.1371/journal.pone.0060397","pdf_url":"https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0060397&type=printable","source":{"id":"https://openalex.org/S202381698","display_name":"PLoS ONE","issn_l":"1932-6203","issn":["1932-6203"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","doaj","dongbi-c","doyens","erih-plus","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315706","host_organization_name":"Public Library of Science","host_organization_lineage":["https://openalex.org/P4310315706"],"host_organization_lineage_names":["Public Library of Science"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLoS ONE","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.6240000128746033,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320334764","display_name":"Japan Society for the Promotion of Science","ror":"https://ror.org/00hhkn466"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2129558341.pdf","grobid_xml":"https://content.openalex.org/works/W2129558341.grobid-xml"},"referenced_works_count":34,"referenced_works":["https://openalex.org/W1886278373","https://openalex.org/W1966056249","https://openalex.org/W1977603207","https://openalex.org/W1980195461","https://openalex.org/W1983993955","https://openalex.org/W1993283403","https://openalex.org/W1996786134","https://openalex.org/W1997299080","https://openalex.org/W1997500225","https://openalex.org/W2009857031","https://openalex.org/W2015357656","https://openalex.org/W2023418900","https://openalex.org/W2027899709","https://openalex.org/W2034091087","https://openalex.org/W2034586537","https://openalex.org/W2035837644","https://openalex.org/W2036700858","https://openalex.org/W2042624473","https://openalex.org/W2050775539","https://openalex.org/W2057500222","https://openalex.org/W2058876100","https://openalex.org/W2084276537","https://openalex.org/W2088442622","https://openalex.org/W2093763122","https://openalex.org/W2097117811","https://openalex.org/W2097757455","https://openalex.org/W2113621003","https://openalex.org/W2121277695","https://openalex.org/W2134812217","https://openalex.org/W2141869864","https://openalex.org/W2148379386","https://openalex.org/W2148619403","https://openalex.org/W2154431984","https://openalex.org/W2166174423"],"related_works":["https://openalex.org/W7097152412","https://openalex.org/W1998412506","https://openalex.org/W2036700858","https://openalex.org/W2058876100","https://openalex.org/W2141869864","https://openalex.org/W2113621003","https://openalex.org/W3189658526","https://openalex.org/W1984188752","https://openalex.org/W2334475067","https://openalex.org/W4415817344"],"abstract_inverted_index":{"Increased":[0],"levels":[1],"of":[2,23,60,72,107,116],"N-linked":[3],"(\u03b2-N-":[4],"acetylglucosamine)2":[5],"[N-GlcNAc2]-modified":[6],"proteins":[7,50,85,90,128],"have":[8],"been":[9],"recognized":[10],"to":[11,16],"be":[12],"an":[13],"effective":[14],"response":[15,68,110,136,143],"glucose":[17,39,52,99,120,131],"deprivation.":[18,53,121],"In":[19],"the":[20,33,61,92,105,113,138],"first":[21],"step":[22],"this":[24,142],"study,":[25],"using":[26],"a":[27,42],"next":[28],"generation":[29],"sequencer,":[30],"we":[31],"investigated":[32],"global":[34],"transcriptional":[35],"changes":[36],"induced":[37,112,144],"by":[38,98],"deprivation":[40,100,132],"in":[41,91,101,137],"T24":[43,102],"bladder":[44],"carcinoma":[45],"cell":[46],"line,":[47],"producing":[48],"N-GlcNAc2-modified":[49,84,127],"under":[51,119,130],"Our":[54,79],"transcriptome":[55],"analysis":[56,81],"revealed":[57],"significant":[58],"up-regulation":[59],"UDP-GlcNAc":[62],"biosynthesis":[63],"pathway":[64],"and":[65,70,140],"unfolded":[66,108,134],"protein":[67,109,135],"genes,":[69],"down-regulation":[71],"G2/M":[73,94,145],"transition-related":[74],"genes":[75,111],"containing":[76],"mitotic":[77,117],"kinases.":[78],"biological":[80],"confirmed":[82],"that":[83,141],"were":[86],"localized":[87],"with":[88],"BiP":[89],"ER.":[93],"arrest":[95],"was":[96],"caused":[97,133],"cells.":[103],"Moreover,":[104],"knockdown":[106],"expressional":[114],"recovery":[115],"kinases":[118],"Taken":[122],"together,":[123],"our":[124],"results":[125],"suggest":[126],"produced":[129],"ER,":[139],"arrest.":[146]},"counts_by_year":[{"year":2023,"cited_by_count":2},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":1},{"year":2018,"cited_by_count":1},{"year":2017,"cited_by_count":1},{"year":2016,"cited_by_count":3},{"year":2015,"cited_by_count":2},{"year":2014,"cited_by_count":1}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2016-06-24T00:00:00"}