{"id":"https://openalex.org/W2129405502","doi":null,"title":"Nutritional support of bone marrow transplant recipients: a prospective, randomized clinical trial comparing total parenteral nutrition to an enteral feeding program.","display_name":"Nutritional support of bone marrow transplant recipients: a prospective, randomized clinical trial comparing total parenteral nutrition to an enteral feeding program.","publication_year":1987,"publication_date":"1987-06-15","ids":{"openalex":"https://openalex.org/W2129405502","mag":"2129405502","pmid":"https://pubmed.ncbi.nlm.nih.gov/3107808"},"language":"en","primary_location":{"id":"pmid:3107808","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/3107808","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cancer research","raw_type":"Clinical Trial"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5073080789","display_name":"Delira J. Szeluga","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"D J Szeluga","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5015493242","display_name":"Robert Kenneth Stuart","orcid":"https://orcid.org/0000-0001-7549-8008","observed_orcids":["https://orcid.org/0000-0001-7549-8008"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"R K Stuart","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5073783403","display_name":"Ron Brookmeyer","orcid":"https://orcid.org/0000-0002-8639-3399","observed_orcids":["https://orcid.org/0000-0002-8639-3399"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"R Brookmeyer","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5072112987","display_name":"Virginia Utermohlen","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"V Utermohlen","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5109115242","display_name":"George W. Santos","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"G W Santos","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":4.476,"has_fulltext":false,"cited_by_count":186,"citation_normalized_percentile":{"value":0.94739819,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":87,"max":99},"biblio":{"volume":"47","issue":"12","first_page":"3309","last_page":"16"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10858","display_name":"Clinical Nutrition and Gastroenterology","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2916","display_name":"Nutrition and Dietetics"},"field":{"id":"https://openalex.org/fields/29","display_name":"Nursing"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10858","display_name":"Clinical Nutrition and Gastroenterology","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2916","display_name":"Nutrition and Dietetics"},"field":{"id":"https://openalex.org/fields/29","display_name":"Nursing"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10397","display_name":"Nutrition and Health in Aging","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12279","display_name":"Body Composition Measurement Techniques","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/bone-marrow-transplantation","display_name":"bone marrow transplantation","score":0.9570000171661377},{"id":"https://openalex.org/keywords/nutritional-support","display_name":"nutritional support","score":0.8379999995231628},{"id":"https://openalex.org/keywords/total-parenteral-nutrition","display_name":"total parenteral nutrition","score":1.0},{"id":"https://openalex.org/keywords/enteral-nutrition","display_name":"enteral nutrition","score":0.9679999947547913},{"id":"https://openalex.org/keywords/body-composition","display_name":"body composition","score":0.953000009059906},{"id":"https://openalex.org/keywords/body-cell-mass","display_name":"body cell mass","score":0.9670000076293945},{"id":"https://openalex.org/keywords/extracellular-fluid","display_name":"extracellular fluid","score":0.8640000224113464},{"id":"https://openalex.org/keywords/serum-proteins","display_name":"serum proteins","score":0.6430000066757202},{"id":"https://openalex.org/keywords/hyperglycemia","display_name":"hyperglycemia","score":0.718999981880188},{"id":"https://openalex.org/keywords/catheter-related-complications","display_name":"catheter-related complications","score":0.843999981880188},{"id":"https://openalex.org/keywords/hypomagnesemia","display_name":"hypomagnesemia","score":0.949999988079071},{"id":"https://openalex.org/keywords/hematopoietic-recovery","display_name":"hematopoietic recovery","score":0.8429999947547913}],"concepts":[{"id":"https://openalex.org/C78722104","wikidata":"https://www.wikidata.org/wiki/Q21653202","display_name":"Parenteral nutrition","level":2,"score":0.8811689019203186},{"id":"https://openalex.org/C44315111","wikidata":"https://www.wikidata.org/wiki/Q1344580","display_name":"Enteral administration","level":3,"score":0.8327001333236694},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.7980059385299683},{"id":"https://openalex.org/C168563851","wikidata":"https://www.wikidata.org/wiki/Q1436668","display_name":"Randomized controlled trial","level":2,"score":0.48856648802757263},{"id":"https://openalex.org/C188816634","wikidata":"https://www.wikidata.org/wiki/Q2113324","display_name":"Prospective cohort study","level":2,"score":0.47348248958587646},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.4609791040420532},{"id":"https://openalex.org/C2776183862","wikidata":"https://www.wikidata.org/wiki/Q3771629","display_name":"Hypomagnesemia","level":3,"score":0.459542453289032},{"id":"https://openalex.org/C90924648","wikidata":"https://www.wikidata.org/wiki/Q120569","display_name":"Gastroenterology","level":1,"score":0.4077492654323578},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.3487166166305542},{"id":"https://openalex.org/C543218039","wikidata":"https://www.wikidata.org/wiki/Q660","display_name":"Magnesium","level":2,"score":0.0},{"id":"https://openalex.org/C191897082","wikidata":"https://www.wikidata.org/wiki/Q11467","display_name":"Metallurgy","level":1,"score":0.0},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D000293","descriptor_name":"Adolescent","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001834","descriptor_name":"Body Water","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D002648","descriptor_name":"Child","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002986","descriptor_name":"Clinical Trials as Topic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004232","descriptor_name":"Diuretics","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D004750","descriptor_name":"Enteral Nutrition","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D005110","descriptor_name":"Extracellular Space","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007945","descriptor_name":"Leukemia, Lymphoid","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":false},{"descriptor_ui":"D007951","descriptor_name":"Leukemia, Myeloid","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010289","descriptor_name":"Parenteral Nutrition, Total","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D011446","descriptor_name":"Prospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015470","descriptor_name":"Leukemia, Myeloid, Acute","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":false},{"descriptor_ui":"D016026","descriptor_name":"Bone Marrow Transplantation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":2,"locations":[{"id":"pmid:3107808","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/3107808","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cancer research","raw_type":"Clinical Trial"},{"id":"mag:2129405502","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/3107808","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":1.0,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Randomized Controlled Trial","id":"https://openalex.org/study-designs/randomized-controlled-trial"},{"display_name":"Clinical Trial","id":"https://openalex.org/study-designs/clinical-trial"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":60,"referenced_works":["https://openalex.org/W47110463","https://openalex.org/W48138642","https://openalex.org/W180147385","https://openalex.org/W317817448","https://openalex.org/W1266299855","https://openalex.org/W1531270645","https://openalex.org/W1580788756","https://openalex.org/W1755081876","https://openalex.org/W1893499759","https://openalex.org/W1930829416","https://openalex.org/W1965427104","https://openalex.org/W1967294547","https://openalex.org/W1974272625","https://openalex.org/W1976787064","https://openalex.org/W1980620287","https://openalex.org/W1993436941","https://openalex.org/W1999324663","https://openalex.org/W2000423969","https://openalex.org/W2003207493","https://openalex.org/W2014090617","https://openalex.org/W2016821655","https://openalex.org/W2021772464","https://openalex.org/W2023819543","https://openalex.org/W2037468861","https://openalex.org/W2049249958","https://openalex.org/W2059667904","https://openalex.org/W2068753150","https://openalex.org/W2069541559","https://openalex.org/W2071307117","https://openalex.org/W2072278955","https://openalex.org/W2078851657","https://openalex.org/W2082491559","https://openalex.org/W2089758601","https://openalex.org/W2109249523","https://openalex.org/W2133406706","https://openalex.org/W2136364350","https://openalex.org/W2139984188","https://openalex.org/W2143594378","https://openalex.org/W2144601461","https://openalex.org/W2148160285","https://openalex.org/W2154395203","https://openalex.org/W2158872694","https://openalex.org/W2214790450","https://openalex.org/W2255693183","https://openalex.org/W2331148235","https://openalex.org/W2339482838","https://openalex.org/W2396093778","https://openalex.org/W2407986822","https://openalex.org/W2408875502","https://openalex.org/W2413804003","https://openalex.org/W2413887409","https://openalex.org/W2414172339","https://openalex.org/W2416285140","https://openalex.org/W2417323158","https://openalex.org/W2420344814","https://openalex.org/W2428252341","https://openalex.org/W2435358460","https://openalex.org/W2436160539","https://openalex.org/W2507882953","https://openalex.org/W2896948216"],"related_works":["https://openalex.org/W4821369","https://openalex.org/W2123880965","https://openalex.org/W2022389985","https://openalex.org/W2014125864","https://openalex.org/W2031194023","https://openalex.org/W2063997328","https://openalex.org/W1982488054","https://openalex.org/W2053995742","https://openalex.org/W2419128023","https://openalex.org/W2014090617"],"abstract_inverted_index":{"Although":[0],"standard":[1,89],"supportive":[2],"care":[3],"for":[4,247],"bone":[5],"marrow":[6],"transplant":[7],"(BMT)":[8],"recipients":[9,35],"includes":[10],"total":[11,80],"parenteral":[12],"nutrition":[13],"(TPN),":[14],"it":[15],"has":[16],"not":[17,234],"been":[18],"shown":[19],"that":[20,231,243],"this":[21],"is":[22,233],"the":[23,39,78,158,173,208,226],"most":[24],"appropriate":[25],"method":[26],"of":[27,69,123,183,210,214],"nutritional":[28],"support.":[29],"To":[30],"determine":[31],"whether":[32],"current":[33],"BMT":[34,248],"require":[36],"TPN":[37,51,111,177,227,232,244],"during":[38],"early":[40],"recovery":[41],"period,":[42],"we":[43],"conducted":[44],"a":[45,121],"prospective,":[46],"randomized":[47],"clinical":[48],"trial":[49],"comparing":[50],"and":[52,73,83,93,100,137,152,189,241],"an":[53],"individualized":[54,238],"enteral":[55,140,174,239,254],"feeding":[56,141,175,240],"program":[57,142],"(counseling,":[58],"high":[59],"protein":[60],"snacks":[61],"and/or":[62],"tube":[63],"feeding).":[64],"Nutritional":[65],"assessment":[66],"included":[67],"measurement":[68],"serum":[70],"proteins,":[71],"anthropometry,":[72],"body":[74,81,97,101,113,126,145],"composition":[75,114],"analysis.":[76],"For":[77],"latter,":[79],"water":[82],"extracellular":[84,104,130,149],"fluid":[85],"were":[86,203,221],"measured":[87],"by":[88,195],"radioisotope":[90],"dilution":[91],"techniques":[92],"used":[94],"to":[95,172,237,253],"quantitate":[96],"cell":[98,127,146],"mass":[99],"fat":[102],"plus":[103],"solids":[105],"(FAT":[106],"+":[107,134,154,162],"ECS).":[108],"In":[109],"27":[110],"patients,":[112,143],"28":[115],"days":[116,182],"after":[117],"BMT,":[118],"expressed":[119],"as":[120],"percentage":[122],"baseline,":[124],"was":[125,144,164,178],"mass,":[128,147],"100%,":[129],"fluid,":[131,150],"108%,":[132,136],"FAT":[133,153,161],"ECS,":[135,155],"in":[138,160,207,225],"30":[139],"93%,":[148],"104%,":[151],"94%.":[156],"Only":[157],"difference":[159],"ECS":[163],"statistically":[165],"significant":[166,205],"(p":[167],"less":[168,199],"than":[169],"0.01).":[170],"Compared":[171],"program,":[176],"associated":[179],"with":[180],"more":[181,186,190],"diuretic":[184],"use,":[185],"frequent":[187,191,200],"hyperglycemia,":[188],"catheter":[192],"removal":[193],"(prompted":[194],"catheter-related":[196],"complications),":[197],"but":[198,218],"hypomagnesemia.":[201],"There":[202],"no":[204],"differences":[206],"rate":[209],"hematopoietic":[211],"recovery,":[212],"length":[213],"hospitalization,":[215],"or":[216],"survival,":[217],"nutrition-related":[219],"costs":[220],"2.3":[222],"times":[223],"greater":[224],"group.":[228],"We":[229],"conclude":[230],"clearly":[235],"superior":[236],"recommend":[242],"be":[245],"reserved":[246],"patients":[249],"who":[250],"demonstrate":[251],"intolerance":[252],"feeding.":[255]},"counts_by_year":[{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":1},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":2},{"year":2019,"cited_by_count":7},{"year":2018,"cited_by_count":3},{"year":2017,"cited_by_count":9},{"year":2016,"cited_by_count":5},{"year":2015,"cited_by_count":7},{"year":2014,"cited_by_count":6},{"year":2013,"cited_by_count":4},{"year":2012,"cited_by_count":7}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}