{"id":"https://openalex.org/W2129391502","doi":"https://doi.org/10.1109/nebc.2007.4413339","title":"Micro-stamped ECM proteins enhance endothelial cell adhesion and directed growth","display_name":"Micro-stamped ECM proteins enhance endothelial cell adhesion and directed growth","publication_year":2007,"publication_date":"2007-03-01","ids":{"openalex":"https://openalex.org/W2129391502","doi":"https://doi.org/10.1109/nebc.2007.4413339","mag":"2129391502"},"language":"en","primary_location":{"id":"doi:10.1109/nebc.2007.4413339","doi":"https://doi.org/10.1109/nebc.2007.4413339","is_oa":false,"landing_page_url":"https://doi.org/10.1109/nebc.2007.4413339","pdf_url":null,"source":{"id":"https://openalex.org/S4393916914","display_name":"IEEE Annual Northeast Bioengineering Conference (NEBEC)","issn_l":"1071-121X","issn":["1071-121X"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"conference"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2007 IEEE 33rd Annual Northeast Bioengineering Conference","raw_type":"proceedings-article"},"volume":null,"type":"conference-paper","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5024030565","display_name":"David Alan Rubenstein","orcid":"https://orcid.org/0000-0002-9495-9049","observed_orcids":["https://orcid.org/0000-0002-9495-9049"]},"institutions":[{"id":"https://openalex.org/I59553526","display_name":"Stony Brook University","ror":"https://ror.org/05qghxh33","country_code":"US","type":"education","lineage":["https://openalex.org/I59553526"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"D.A. Rubenstein","raw_affiliation_strings":["Department of Biomedical Engineering, State University of New York, Stony Brook, Stony Brook, NY, USA","State Univ. of New York-Stony Brook, Stony Brook"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biomedical Engineering, State University of New York, Stony Brook, Stony Brook, NY, USA","institution_ids":["https://openalex.org/I59553526"]},{"raw_affiliation_string":"State Univ. of New York-Stony Brook, Stony Brook","institution_ids":["https://openalex.org/I59553526"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5085199685","display_name":"Mary D. S. Frame","orcid":"https://orcid.org/0000-0003-3890-2221","observed_orcids":["https://orcid.org/0000-0003-3890-2221"]},"institutions":[{"id":"https://openalex.org/I59553526","display_name":"Stony Brook University","ror":"https://ror.org/05qghxh33","country_code":"US","type":"education","lineage":["https://openalex.org/I59553526"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"M.D. Frame","raw_affiliation_strings":["Department of Biomedical Engineering, State University of New York, Stony Brook, Stony Brook, NY, USA","State Univ. of New York-Stony Brook, Stony Brook"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biomedical Engineering, State University of New York, Stony Brook, Stony Brook, NY, USA","institution_ids":["https://openalex.org/I59553526"]},{"raw_affiliation_string":"State Univ. of New York-Stony Brook, Stony Brook","institution_ids":["https://openalex.org/I59553526"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I59553526"],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":2,"citation_normalized_percentile":{"value":0.21805792,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":94},"biblio":{"volume":null,"issue":null,"first_page":"183","last_page":"184"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10379","display_name":"Cellular Mechanics and Interactions","score":0.9448000192642212,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10379","display_name":"Cellular Mechanics and Interactions","score":0.9448000192642212,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11190","display_name":"3D Printing in Biomedical Research","score":0.01720000058412552,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T12224","display_name":"Nanofabrication and Lithography Techniques","score":0.013399999588727951,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/microstamping","display_name":"microstamping","score":0.6980000138282776},{"id":"https://openalex.org/keywords/extracellular-matrix-proteins","display_name":"extracellular matrix proteins","score":0.984000027179718},{"id":"https://openalex.org/keywords/endothelial-cell-adhesion","display_name":"endothelial cell adhesion","score":0.9190000295639038},{"id":"https://openalex.org/keywords/microvascular-endothelial-cells","display_name":"microvascular endothelial cells","score":0.8230000138282776},{"id":"https://openalex.org/keywords/photolithography","display_name":"photolithography","score":0.718999981880188},{"id":"https://openalex.org/keywords/soft-lithography","display_name":"soft lithography","score":0.8769999742507935},{"id":"https://openalex.org/keywords/fibronectin","display_name":"fibronectin","score":0.8569999933242798},{"id":"https://openalex.org/keywords/laminin","display_name":"laminin","score":0.9990000128746033},{"id":"https://openalex.org/keywords/type-i-collagen","display_name":"type I collagen","score":0.8349999785423279},{"id":"https://openalex.org/keywords/type-iv-collagen","display_name":"type IV collagen","score":0.9980000257492065},{"id":"https://openalex.org/keywords/cell-morphology","display_name":"cell morphology","score":0.8190000057220459},{"id":"https://openalex.org/keywords/cell-density","display_name":"cell density","score":0.6439999938011169},{"id":"https://openalex.org/keywords/cell-patterning","display_name":"cell patterning","score":0.6209999918937683}],"concepts":[{"id":"https://openalex.org/C189165786","wikidata":"https://www.wikidata.org/wiki/Q193825","display_name":"Extracellular matrix","level":2,"score":0.847137451171875},{"id":"https://openalex.org/C86492073","wikidata":"https://www.wikidata.org/wiki/Q413766","display_name":"Fibronectin","level":3,"score":0.8452900648117065},{"id":"https://openalex.org/C2779814568","wikidata":"https://www.wikidata.org/wiki/Q58345","display_name":"Laminin","level":3,"score":0.627852737903595},{"id":"https://openalex.org/C84416704","wikidata":"https://www.wikidata.org/wiki/Q188666","display_name":"Adhesion","level":2,"score":0.5489058494567871},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.5268306136131287},{"id":"https://openalex.org/C85789140","wikidata":"https://www.wikidata.org/wiki/Q187640","display_name":"Cell adhesion","level":3,"score":0.5212103128433228},{"id":"https://openalex.org/C123012128","wikidata":"https://www.wikidata.org/wiki/Q5376430","display_name":"Endothelial stem cell","level":3,"score":0.5072224140167236},{"id":"https://openalex.org/C106487976","wikidata":"https://www.wikidata.org/wiki/Q685816","display_name":"Matrix (chemical analysis)","level":2,"score":0.4514899253845215},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.4267214238643646},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.4148622751235962},{"id":"https://openalex.org/C171250308","wikidata":"https://www.wikidata.org/wiki/Q11468","display_name":"Nanotechnology","level":1,"score":0.37846291065216064},{"id":"https://openalex.org/C12554922","wikidata":"https://www.wikidata.org/wiki/Q7100","display_name":"Biophysics","level":1,"score":0.32312726974487305},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.2311471402645111},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.1442202925682068},{"id":"https://openalex.org/C159985019","wikidata":"https://www.wikidata.org/wiki/Q181790","display_name":"Composite material","level":1,"score":0.09559512138366699},{"id":"https://openalex.org/C202751555","wikidata":"https://www.wikidata.org/wiki/Q221681","display_name":"In vitro","level":2,"score":0.08344200253486633}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1109/nebc.2007.4413339","doi":"https://doi.org/10.1109/nebc.2007.4413339","is_oa":false,"landing_page_url":"https://doi.org/10.1109/nebc.2007.4413339","pdf_url":null,"source":{"id":"https://openalex.org/S4393916914","display_name":"IEEE Annual Northeast Bioengineering Conference (NEBEC)","issn_l":"1071-121X","issn":["1071-121X"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"conference"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2007 IEEE 33rd Annual Northeast Bioengineering Conference","raw_type":"proceedings-article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.4043000042438507,"display_name":"Good health and well-being"}],"sustainable_development_goals_aurora":[],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":4,"referenced_works":["https://openalex.org/W2020982577","https://openalex.org/W2058096164","https://openalex.org/W2113739044","https://openalex.org/W4232020681"],"related_works":["https://openalex.org/W1973033463","https://openalex.org/W1970541858","https://openalex.org/W2080218770","https://openalex.org/W2047749203","https://openalex.org/W2073846931","https://openalex.org/W1967279703","https://openalex.org/W2083252577","https://openalex.org/W1968129543","https://openalex.org/W2085635421","https://openalex.org/W3199512845"],"abstract_inverted_index":{"Our":[0],"goal":[1],"was":[2,24,82,97],"to":[3,26,114],"evaluate":[4],"microvascular":[5,37],"endothelial":[6,38,119],"cell":[7,95],"growth":[8,117],"on":[9,47,52,63,77,100,107],"hydrophilic":[10],"glass":[11],"surfaces":[12],"micro-stamped":[13],"with":[14],"extracellular":[15],"matrix":[16],"proteins":[17],"(ECM).":[18],"A":[19],"combination":[20],"of":[21,84,118,123],"photo-and":[22],"soft-lithography":[23],"used":[25],"fabricate":[27],"microstamps.":[28],"We":[29],"hypothesized":[30],"that":[31],"by":[32],"day":[33,68],"3,":[34,69],"human":[35],"dermal":[36],"cells":[39,120],"(hDMECs)":[40],"would":[41,60],"have":[42],"higher":[43],"viability":[44],"and":[45,92],"density":[46,76],"the":[48,64,78,85,112,116],"patterned":[49],"matrices":[50],"vs.":[51],"bare":[53,108],"glass.":[54,109],"Also,":[55],"our":[56],"preferential":[57],"elongated":[58,99],"morphology":[59,96],"be":[61],"heightened":[62],"stamped":[65,79],"matrix.":[66],"By":[67],"we":[70],"saw":[71],"a":[72],"four-fold":[73],"increase":[74],"in":[75],"proteins.":[80,126],"Viability":[81],"independent":[83],"ECM":[86,102,125],"type":[87],"(fibronectin,":[88],"laminin,":[89],"collagen":[90],"I":[91],"IV).":[93],"Endothelial":[94],"preferentially":[98],"each":[101],"type,":[103],"more":[104],"so":[105],"than":[106],"This":[110],"demonstrates":[111],"ability":[113],"concentrate":[115],"within":[121],"regions":[122],"microstamped":[124]},"counts_by_year":[{"year":2017,"cited_by_count":1},{"year":2015,"cited_by_count":1}],"updated_date":"2026-10-26T11:51:55.731654","created_date":"2016-06-24T00:00:00"}