{"id":"https://openalex.org/W2129266175","doi":"https://doi.org/10.1016/s0006-291x(02)00821-5","title":"Hemodynamic effects of exogenous adrenomedullin in healthy and endotoxemic sheep","display_name":"Hemodynamic effects of exogenous adrenomedullin in healthy and endotoxemic sheep","publication_year":2002,"publication_date":"2002-08-01","ids":{"openalex":"https://openalex.org/W2129266175","doi":"https://doi.org/10.1016/s0006-291x(02)00821-5","mag":"2129266175","pmid":"https://pubmed.ncbi.nlm.nih.gov/12147239"},"language":"en","primary_location":{"id":"doi:10.1016/s0006-291x(02)00821-5","doi":"https://doi.org/10.1016/s0006-291x(02)00821-5","is_oa":false,"landing_page_url":"https://doi.org/10.1016/s0006-291x(02)00821-5","pdf_url":null,"source":{"id":"https://openalex.org/S151589183","display_name":"Biochemical and Biophysical Research Communications","issn_l":"0006-291X","issn":["0006-291X","1090-2104"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biochemical and Biophysical Research Communications","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5108383045","display_name":"Martin Westphal","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I22465464","display_name":"University of M\u00fcnster","ror":"https://ror.org/00pd74e08","country_code":"DE","type":"education","lineage":["https://openalex.org/I22465464"]}],"countries":["DE"],"is_corresponding":true,"raw_author_name":"Martin Westphal","raw_affiliation_strings":["Department of Anaesthesiology and Intensive Care, University of M\u00fcnster, Albert-Schweitzer-Strasse 33, 48149, M\u00fcnster, Germany. mwestpha@uni-muenster.de","Department of Anaesthesiology and Intensive Care, University of M\u00fcnster, Albert-Schweitzer-Strasse 33, 48149, M\u00fcnster, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Anaesthesiology and Intensive Care, University of M\u00fcnster, Albert-Schweitzer-Strasse 33, 48149, M\u00fcnster, Germany. mwestpha@uni-muenster.de","institution_ids":["https://openalex.org/I22465464"]},{"raw_affiliation_string":"Department of Anaesthesiology and Intensive Care, University of M\u00fcnster, Albert-Schweitzer-Strasse 33, 48149, M\u00fcnster, Germany","institution_ids":["https://openalex.org/I22465464"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110240149","display_name":"Henning Dirk Stubbe","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I22465464","display_name":"University of M\u00fcnster","ror":"https://ror.org/00pd74e08","country_code":"DE","type":"education","lineage":["https://openalex.org/I22465464"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Henning Stubbe","raw_affiliation_strings":["Department of Anaesthesiology and Intensive Care, University of M\u00fcnster, Albert-Schweitzer-Strasse 33, 48149, M\u00fcnster, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Anaesthesiology and Intensive Care, University of M\u00fcnster, Albert-Schweitzer-Strasse 33, 48149, M\u00fcnster, Germany","institution_ids":["https://openalex.org/I22465464"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111699463","display_name":"Hans-Georg Bone","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I22465464","display_name":"University of M\u00fcnster","ror":"https://ror.org/00pd74e08","country_code":"DE","type":"education","lineage":["https://openalex.org/I22465464"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Hans-Georg Bone","raw_affiliation_strings":["Department of Anaesthesiology and Intensive Care, University of M\u00fcnster, Albert-Schweitzer-Strasse 33, 48149, M\u00fcnster, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Anaesthesiology and Intensive Care, University of M\u00fcnster, Albert-Schweitzer-Strasse 33, 48149, M\u00fcnster, Germany","institution_ids":["https://openalex.org/I22465464"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5048930012","display_name":"Fritz Daudel","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I22465464","display_name":"University of M\u00fcnster","ror":"https://ror.org/00pd74e08","country_code":"DE","type":"education","lineage":["https://openalex.org/I22465464"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Fritz Daudel","raw_affiliation_strings":["Department of Anaesthesiology and Intensive Care, University of M\u00fcnster, Albert-Schweitzer-Strasse 33, 48149, M\u00fcnster, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Anaesthesiology and Intensive Care, University of M\u00fcnster, Albert-Schweitzer-Strasse 33, 48149, M\u00fcnster, Germany","institution_ids":["https://openalex.org/I22465464"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5056892295","display_name":"Sebastian Vocke","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I22465464","display_name":"University of M\u00fcnster","ror":"https://ror.org/00pd74e08","country_code":"DE","type":"education","lineage":["https://openalex.org/I22465464"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Sebastian Vocke","raw_affiliation_strings":["Department of Anaesthesiology and Intensive Care, University of M\u00fcnster, Albert-Schweitzer-Strasse 33, 48149, M\u00fcnster, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Anaesthesiology and Intensive Care, University of M\u00fcnster, Albert-Schweitzer-Strasse 33, 48149, M\u00fcnster, Germany","institution_ids":["https://openalex.org/I22465464"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5018281416","display_name":"Hugo Van Aken","orcid":"https://orcid.org/0000-0001-6878-9851","observed_orcids":["https://orcid.org/0000-0001-6878-9851"]},"institutions":[{"id":"https://openalex.org/I22465464","display_name":"University of M\u00fcnster","ror":"https://ror.org/00pd74e08","country_code":"DE","type":"education","lineage":["https://openalex.org/I22465464"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Hugo Van Aken","raw_affiliation_strings":["Department of Anaesthesiology and Intensive Care, University of M\u00fcnster, Albert-Schweitzer-Strasse 33, 48149, M\u00fcnster, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Anaesthesiology and Intensive Care, University of M\u00fcnster, Albert-Schweitzer-Strasse 33, 48149, M\u00fcnster, Germany","institution_ids":["https://openalex.org/I22465464"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5034076234","display_name":"Michael Booke","orcid":"https://orcid.org/0000-0002-7492-5597","observed_orcids":["https://orcid.org/0000-0002-7492-5597"]},"institutions":[{"id":"https://openalex.org/I22465464","display_name":"University of M\u00fcnster","ror":"https://ror.org/00pd74e08","country_code":"DE","type":"education","lineage":["https://openalex.org/I22465464"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Michael Booke","raw_affiliation_strings":["Department of Anaesthesiology and Intensive Care, University of M\u00fcnster, Albert-Schweitzer-Strasse 33, 48149, M\u00fcnster, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Anaesthesiology and Intensive Care, University of M\u00fcnster, Albert-Schweitzer-Strasse 33, 48149, M\u00fcnster, Germany","institution_ids":["https://openalex.org/I22465464"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5108383045"],"corresponding_institution_ids":["https://openalex.org/I22465464"],"apc_list":{"value":3110,"currency":"USD","value_usd":3110},"apc_paid":null,"fwci":2.4034,"has_fulltext":false,"cited_by_count":33,"citation_normalized_percentile":{"value":0.8917267,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":96},"biblio":{"volume":"296","issue":"1","first_page":"134","last_page":"138"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10218","display_name":"Sepsis Diagnosis and Treatment","score":0.9160000085830688,"subfield":{"id":"https://openalex.org/subfields/2706","display_name":"Critical Care and Intensive Care Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10218","display_name":"Sepsis Diagnosis and Treatment","score":0.9160000085830688,"subfield":{"id":"https://openalex.org/subfields/2706","display_name":"Critical Care and Intensive Care Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10814","display_name":"Neuropeptides and Animal Physiology","score":0.07039999961853027,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11700","display_name":"Hemodynamic Monitoring and Therapy","score":0.0026000000070780516,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/adrenomedullin","display_name":"adrenomedullin","score":0.9990000128746033},{"id":"https://openalex.org/keywords/endotoxemia","display_name":"endotoxemia","score":0.9070000052452087},{"id":"https://openalex.org/keywords/sepsis","display_name":"sepsis","score":0.9670000076293945},{"id":"https://openalex.org/keywords/hemodynamics","display_name":"hemodynamics","score":0.5920000076293945},{"id":"https://openalex.org/keywords/vasodilation","display_name":"vasodilation","score":0.8970000147819519},{"id":"https://openalex.org/keywords/pulmonary-vascular-resistance","display_name":"pulmonary vascular resistance","score":0.8700000047683716},{"id":"https://openalex.org/keywords/hyperdynamic-circulation","display_name":"hyperdynamic circulation","score":0.746999979019165},{"id":"https://openalex.org/keywords/systemic-inflammation","display_name":"systemic inflammation","score":0.6340000033378601},{"id":"https://openalex.org/keywords/sheep-model","display_name":"sheep model","score":0.5630000233650208},{"id":"https://openalex.org/keywords/cardiac-index","display_name":"cardiac index","score":0.7160000205039978}],"concepts":[{"id":"https://openalex.org/C2777152744","wikidata":"https://www.wikidata.org/wiki/Q366935","display_name":"Adrenomedullin","level":3,"score":0.9327515959739685},{"id":"https://openalex.org/C2778384902","wikidata":"https://www.wikidata.org/wiki/Q183134","display_name":"Sepsis","level":2,"score":0.7964594960212708},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.7605511546134949},{"id":"https://openalex.org/C58245268","wikidata":"https://www.wikidata.org/wiki/Q456026","display_name":"Vascular resistance","level":3,"score":0.6594619154930115},{"id":"https://openalex.org/C178853913","wikidata":"https://www.wikidata.org/wiki/Q1642137","display_name":"Hemodynamics","level":2,"score":0.6565544009208679},{"id":"https://openalex.org/C120770815","wikidata":"https://www.wikidata.org/wiki/Q14859627","display_name":"Vasodilation","level":2,"score":0.6138649582862854},{"id":"https://openalex.org/C72859922","wikidata":"https://www.wikidata.org/wiki/Q11068","display_name":"Circulatory system","level":2,"score":0.585464596748352},{"id":"https://openalex.org/C139940330","wikidata":"https://www.wikidata.org/wiki/Q596579","display_name":"Cardiac output","level":3,"score":0.5180999636650085},{"id":"https://openalex.org/C31861589","wikidata":"https://www.wikidata.org/wiki/Q618068","display_name":"Cardiac index","level":4,"score":0.5107576847076416},{"id":"https://openalex.org/C2779065481","wikidata":"https://www.wikidata.org/wiki/Q8578745","display_name":"Hyperdynamic circulation","level":4,"score":0.469434529542923},{"id":"https://openalex.org/C63645605","wikidata":"https://www.wikidata.org/wiki/Q103191","display_name":"Homeostasis","level":2,"score":0.45189762115478516},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.42883992195129395},{"id":"https://openalex.org/C2778198053","wikidata":"https://www.wikidata.org/wiki/Q181754","display_name":"Heart failure","level":2,"score":0.42473727464675903},{"id":"https://openalex.org/C2776914184","wikidata":"https://www.wikidata.org/wiki/Q101991","display_name":"Inflammation","level":2,"score":0.41640031337738037},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.340317964553833},{"id":"https://openalex.org/C164705383","wikidata":"https://www.wikidata.org/wiki/Q10379","display_name":"Cardiology","level":1,"score":0.32434698939323425},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006439","descriptor_name":"Hemodynamics","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D007262","descriptor_name":"Infusions, Intravenous","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010455","descriptor_name":"Peptides","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":false},{"descriptor_ui":"D010455","descriptor_name":"Peptides","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D011446","descriptor_name":"Prospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012756","descriptor_name":"Sheep","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019446","descriptor_name":"Endotoxemia","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":true},{"descriptor_ui":"D053607","descriptor_name":"Adrenomedullin","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1016/s0006-291x(02)00821-5","doi":"https://doi.org/10.1016/s0006-291x(02)00821-5","is_oa":false,"landing_page_url":"https://doi.org/10.1016/s0006-291x(02)00821-5","pdf_url":null,"source":{"id":"https://openalex.org/S151589183","display_name":"Biochemical and Biophysical Research Communications","issn_l":"0006-291X","issn":["0006-291X","1090-2104"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biochemical and Biophysical Research Communications","raw_type":"journal-article"},{"id":"pmid:12147239","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/12147239","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biochemical and biophysical research communications","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.98580002784729,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":22,"referenced_works":["https://openalex.org/W1978862133","https://openalex.org/W1981492597","https://openalex.org/W1985032866","https://openalex.org/W1999582787","https://openalex.org/W2010556870","https://openalex.org/W2030866439","https://openalex.org/W2036662072","https://openalex.org/W2036983784","https://openalex.org/W2037979222","https://openalex.org/W2063308606","https://openalex.org/W2066837470","https://openalex.org/W2084201100","https://openalex.org/W2088371782","https://openalex.org/W2092942673","https://openalex.org/W2100696348","https://openalex.org/W2112563824","https://openalex.org/W2117872960","https://openalex.org/W2124989492","https://openalex.org/W2130584274","https://openalex.org/W2157454255","https://openalex.org/W2161842193","https://openalex.org/W2322121630"],"related_works":["https://openalex.org/W2941033386","https://openalex.org/W54060847","https://openalex.org/W2144803805","https://openalex.org/W2092942673","https://openalex.org/W2168164850","https://openalex.org/W2036983784","https://openalex.org/W2157454255","https://openalex.org/W1976081136","https://openalex.org/W2106848118","https://openalex.org/W2139232589"],"abstract_inverted_index":null,"counts_by_year":[{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":1},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":1},{"year":2018,"cited_by_count":2},{"year":2017,"cited_by_count":1},{"year":2016,"cited_by_count":1},{"year":2015,"cited_by_count":1},{"year":2013,"cited_by_count":2},{"year":2012,"cited_by_count":1}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2016-06-24T00:00:00"}