{"id":"https://openalex.org/W2129199903","doi":"https://doi.org/10.1039/c4tb00885e","title":"Biofunctionalized pectin hydrogels as 3D cellular microenvironments","display_name":"Biofunctionalized pectin hydrogels as 3D cellular microenvironments","publication_year":2015,"publication_date":"2015-01-01","ids":{"openalex":"https://openalex.org/W2129199903","doi":"https://doi.org/10.1039/c4tb00885e","mag":"2129199903","pmid":"https://pubmed.ncbi.nlm.nih.gov/32262378"},"language":"en","primary_location":{"id":"doi:10.1039/c4tb00885e","doi":"https://doi.org/10.1039/c4tb00885e","is_oa":true,"landing_page_url":"https://doi.org/10.1039/c4tb00885e","pdf_url":"https://pubs.rsc.org/en/content/articlepdf/2015/tb/c4tb00885e","source":{"id":"https://openalex.org/S2479884170","display_name":"Journal of Materials Chemistry B","issn_l":"2050-750X","issn":["2050-750X","2050-7518"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320556","host_organization_name":"Royal Society of Chemistry","host_organization_lineage":["https://openalex.org/P4310320556"],"host_organization_lineage_names":["Royal Society of Chemistry"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Materials Chemistry B","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://pubs.rsc.org/en/content/articlepdf/2015/tb/c4tb00885e","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5065442558","display_name":"Sara C. Neves","orcid":"https://orcid.org/0000-0001-6154-2821","observed_orcids":["https://orcid.org/0000-0001-6154-2821"]},"institutions":[{"id":"https://openalex.org/I182534213","display_name":"Universidade do Porto","ror":"https://ror.org/043pwc612","country_code":"PT","type":"education","lineage":["https://openalex.org/I182534213"]}],"countries":["PT"],"is_corresponding":false,"raw_author_name":"Sara C. Neves","raw_affiliation_strings":["4150-180 Porto","FEUP \u2013 Faculdade de Engenharia da Universidade do Porto","INEB \u2013 Instituto de Engenharia Biom\u00e9dica","Portugal","Universidade do Porto"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"4150-180 Porto","institution_ids":[]},{"raw_affiliation_string":"FEUP \u2013 Faculdade de Engenharia da Universidade do Porto","institution_ids":["https://openalex.org/I182534213"]},{"raw_affiliation_string":"INEB \u2013 Instituto de Engenharia Biom\u00e9dica","institution_ids":[]},{"raw_affiliation_string":"Portugal","institution_ids":[]},{"raw_affiliation_string":"Universidade do Porto","institution_ids":["https://openalex.org/I182534213"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5046074924","display_name":"David B. Gomes","orcid":"https://orcid.org/0000-0003-4075-976X","observed_orcids":["https://orcid.org/0000-0003-4075-976X"]},"institutions":[{"id":"https://openalex.org/I182534213","display_name":"Universidade do Porto","ror":"https://ror.org/043pwc612","country_code":"PT","type":"education","lineage":["https://openalex.org/I182534213"]}],"countries":["PT"],"is_corresponding":false,"raw_author_name":"David B. Gomes","raw_affiliation_strings":["4150-180 Porto","FEUP \u2013 Faculdade de Engenharia da Universidade do Porto","INEB \u2013 Instituto de Engenharia Biom\u00e9dica","Portugal","Universidade do Porto"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"4150-180 Porto","institution_ids":[]},{"raw_affiliation_string":"FEUP \u2013 Faculdade de Engenharia da Universidade do Porto","institution_ids":["https://openalex.org/I182534213"]},{"raw_affiliation_string":"INEB \u2013 Instituto de Engenharia Biom\u00e9dica","institution_ids":[]},{"raw_affiliation_string":"Portugal","institution_ids":[]},{"raw_affiliation_string":"Universidade do Porto","institution_ids":["https://openalex.org/I182534213"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5005975334","display_name":"Aureliana Sousa","orcid":"https://orcid.org/0000-0003-2191-8892","observed_orcids":["https://orcid.org/0000-0003-2191-8892"]},"institutions":[{"id":"https://openalex.org/I182534213","display_name":"Universidade do Porto","ror":"https://ror.org/043pwc612","country_code":"PT","type":"education","lineage":["https://openalex.org/I182534213"]}],"countries":["PT"],"is_corresponding":false,"raw_author_name":"Aureliana Sousa","raw_affiliation_strings":["4150-180 Porto","INEB \u2013 Instituto de Engenharia Biom\u00e9dica","Instituto de Investiga\u00e7\u00e3o e Inova\u00e7\u00e3o em Sa\u00fade","Portugal","Universidade do Porto"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"4150-180 Porto","institution_ids":[]},{"raw_affiliation_string":"INEB \u2013 Instituto de Engenharia Biom\u00e9dica","institution_ids":[]},{"raw_affiliation_string":"Instituto de Investiga\u00e7\u00e3o e Inova\u00e7\u00e3o em Sa\u00fade","institution_ids":[]},{"raw_affiliation_string":"Portugal","institution_ids":[]},{"raw_affiliation_string":"Universidade do Porto","institution_ids":["https://openalex.org/I182534213"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5045729530","display_name":"S\u00edlvia Joana Bidarra","orcid":"https://orcid.org/0000-0002-1515-9597","observed_orcids":["https://orcid.org/0000-0002-1515-9597"]},"institutions":[{"id":"https://openalex.org/I182534213","display_name":"Universidade do Porto","ror":"https://ror.org/043pwc612","country_code":"PT","type":"education","lineage":["https://openalex.org/I182534213"]}],"countries":["PT"],"is_corresponding":false,"raw_author_name":"S\u00edlvia J. Bidarra","raw_affiliation_strings":["4150-180 Porto","INEB \u2013 Instituto de Engenharia Biom\u00e9dica","Instituto de Investiga\u00e7\u00e3o e Inova\u00e7\u00e3o em Sa\u00fade","Portugal","Universidade do Porto"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"4150-180 Porto","institution_ids":[]},{"raw_affiliation_string":"INEB \u2013 Instituto de Engenharia Biom\u00e9dica","institution_ids":[]},{"raw_affiliation_string":"Instituto de Investiga\u00e7\u00e3o e Inova\u00e7\u00e3o em Sa\u00fade","institution_ids":[]},{"raw_affiliation_string":"Portugal","institution_ids":[]},{"raw_affiliation_string":"Universidade do Porto","institution_ids":["https://openalex.org/I182534213"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5053622569","display_name":"Paola Petrini","orcid":"https://orcid.org/0000-0002-5081-5254","observed_orcids":["https://orcid.org/0000-0002-5081-5254"]},"institutions":[{"id":"https://openalex.org/I4210155898","display_name":"National Interuniversity Consortium of Materials Science and Technology","ror":"https://ror.org/04k80k910","country_code":"IT","type":"education","lineage":["https://openalex.org/I4210155898"]},{"id":"https://openalex.org/I93860229","display_name":"Politecnico di Milano","ror":"https://ror.org/01nffqt88","country_code":"IT","type":"education","lineage":["https://openalex.org/I93860229"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Paola Petrini","raw_affiliation_strings":["Dipartimento di Chimica","Laboratorio di Biomateriali","Materiali e Ingegneria Chimica \u2018G. Natta\u2019","Politecnico di Milano","Unit\u00e0 di Ricerca Consorzio INSTM"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Dipartimento di Chimica","institution_ids":[]},{"raw_affiliation_string":"Laboratorio di Biomateriali","institution_ids":[]},{"raw_affiliation_string":"Materiali e Ingegneria Chimica \u2018G. Natta\u2019","institution_ids":[]},{"raw_affiliation_string":"Politecnico di Milano","institution_ids":["https://openalex.org/I93860229"]},{"raw_affiliation_string":"Unit\u00e0 di Ricerca Consorzio INSTM","institution_ids":["https://openalex.org/I4210155898"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5058423562","display_name":"Lorenzo Moroni","orcid":"https://orcid.org/0000-0003-1298-6025","observed_orcids":["https://orcid.org/0000-0003-1298-6025"]},"institutions":[{"id":"https://openalex.org/I94624287","display_name":"University of Twente","ror":"https://ror.org/006hf6230","country_code":"NL","type":"education","lineage":["https://openalex.org/I94624287"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"Lorenzo Moroni","raw_affiliation_strings":["7522 NB Enschede","Department of Tissue Regeneration","MIRA \u2013 Institute for Biomedical Technology and Technical Medicine","The Netherlands","University of Twente"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"7522 NB Enschede","institution_ids":[]},{"raw_affiliation_string":"Department of Tissue Regeneration","institution_ids":[]},{"raw_affiliation_string":"MIRA \u2013 Institute for Biomedical Technology and Technical Medicine","institution_ids":[]},{"raw_affiliation_string":"The Netherlands","institution_ids":[]},{"raw_affiliation_string":"University of Twente","institution_ids":["https://openalex.org/I94624287"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5043186502","display_name":"Cristina Carvalho Barrias","orcid":"https://orcid.org/0000-0002-8178-6134","observed_orcids":["https://orcid.org/0000-0002-8178-6134"]},"institutions":[{"id":"https://openalex.org/I182534213","display_name":"Universidade do Porto","ror":"https://ror.org/043pwc612","country_code":"PT","type":"education","lineage":["https://openalex.org/I182534213"]}],"countries":["PT"],"is_corresponding":false,"raw_author_name":"Cristina C. Barrias","raw_affiliation_strings":["4150-180 Porto","INEB \u2013 Instituto de Engenharia Biom\u00e9dica","Instituto de Investiga\u00e7\u00e3o e Inova\u00e7\u00e3o em Sa\u00fade","Portugal","Universidade do Porto"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"4150-180 Porto","institution_ids":[]},{"raw_affiliation_string":"INEB \u2013 Instituto de Engenharia Biom\u00e9dica","institution_ids":[]},{"raw_affiliation_string":"Instituto de Investiga\u00e7\u00e3o e Inova\u00e7\u00e3o em Sa\u00fade","institution_ids":[]},{"raw_affiliation_string":"Portugal","institution_ids":[]},{"raw_affiliation_string":"Universidade do Porto","institution_ids":["https://openalex.org/I182534213"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5037430942","display_name":"Pedro Lopes Granja","orcid":"https://orcid.org/0000-0003-2761-4929","observed_orcids":["https://orcid.org/0000-0003-2761-4929"]},"institutions":[{"id":"https://openalex.org/I182534213","display_name":"Universidade do Porto","ror":"https://ror.org/043pwc612","country_code":"PT","type":"education","lineage":["https://openalex.org/I182534213"]}],"countries":["PT"],"is_corresponding":true,"raw_author_name":"Pedro L. Granja","raw_affiliation_strings":["4150-180 Porto","FEUP \u2013 Faculdade de Engenharia da Universidade do Porto","INEB \u2013 Instituto de Engenharia Biom\u00e9dica","Portugal","Universidade do Porto"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"4150-180 Porto","institution_ids":[]},{"raw_affiliation_string":"FEUP \u2013 Faculdade de Engenharia da Universidade do Porto","institution_ids":["https://openalex.org/I182534213"]},{"raw_affiliation_string":"INEB \u2013 Instituto de Engenharia Biom\u00e9dica","institution_ids":[]},{"raw_affiliation_string":"Portugal","institution_ids":[]},{"raw_affiliation_string":"Universidade do Porto","institution_ids":["https://openalex.org/I182534213"]}]}],"institutions":[],"countries_distinct_count":3,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5037430942"],"corresponding_institution_ids":["https://openalex.org/I182534213"],"apc_list":null,"apc_paid":null,"fwci":3.1472,"has_fulltext":true,"cited_by_count":105,"citation_normalized_percentile":{"value":0.93112684,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":93,"max":100},"biblio":{"volume":"3","issue":"10","first_page":"2096","last_page":"2108"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10343","display_name":"Hydrogels: synthesis, properties, applications","score":0.9911999702453613,"subfield":{"id":"https://openalex.org/subfields/2502","display_name":"Biomaterials"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10343","display_name":"Hydrogels: synthesis, properties, applications","score":0.9911999702453613,"subfield":{"id":"https://openalex.org/subfields/2502","display_name":"Biomaterials"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T12192","display_name":"Polysaccharides Composition and Applications","score":0.002300000051036477,"subfield":{"id":"https://openalex.org/subfields/1106","display_name":"Food Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12264","display_name":"Tissue Engineering and Regenerative Medicine","score":0.002099999925121665,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/pectin-hydrogels","display_name":"pectin hydrogels","score":0.9959999918937683},{"id":"https://openalex.org/keywords/in-situ-forming-hydrogels","display_name":"in situ forming hydrogels","score":0.921999990940094},{"id":"https://openalex.org/keywords/ionic-gelation","display_name":"ionic gelation","score":0.8610000014305115},{"id":"https://openalex.org/keywords/pectin-purification","display_name":"pectin purification","score":0.8579999804496765},{"id":"https://openalex.org/keywords/cell-adhesive-peptides","display_name":"cell-adhesive peptides","score":0.7200000286102295},{"id":"https://openalex.org/keywords/mesenchymal-stem-cells","display_name":"mesenchymal stem cells","score":0.9419999718666077},{"id":"https://openalex.org/keywords/hydrogel-degradation","display_name":"hydrogel degradation","score":0.6499999761581421},{"id":"https://openalex.org/keywords/viscoelasticity","display_name":"viscoelasticity","score":0.7670000195503235},{"id":"https://openalex.org/keywords/cell-migration","display_name":"cell migration","score":0.39399999380111694},{"id":"https://openalex.org/keywords/extracellular-matrix-production","display_name":"extracellular matrix synthesis","score":0.8059999942779541},{"id":"https://openalex.org/keywords/tissue-engineering-scaffolds","display_name":"tissue engineering scaffolds","score":0.7400000095367432},{"id":"https://openalex.org/keywords/regenerative-medicine","display_name":"regenerative medicine","score":0.8370000123977661}],"concepts":[{"id":"https://openalex.org/C108586683","wikidata":"https://www.wikidata.org/wiki/Q17164826","display_name":"Self-healing hydrogels","level":2,"score":0.8968037962913513},{"id":"https://openalex.org/C2780756937","wikidata":"https://www.wikidata.org/wiki/Q188154","display_name":"Pectin","level":2,"score":0.8094910979270935},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.5631304383277893},{"id":"https://openalex.org/C42360764","wikidata":"https://www.wikidata.org/wiki/Q83588","display_name":"Chemical engineering","level":1,"score":0.4108234643936157},{"id":"https://openalex.org/C12554922","wikidata":"https://www.wikidata.org/wiki/Q7100","display_name":"Biophysics","level":1,"score":0.3635665774345398},{"id":"https://openalex.org/C171250308","wikidata":"https://www.wikidata.org/wiki/Q11468","display_name":"Nanotechnology","level":1,"score":0.3549811840057373},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.2359699010848999},{"id":"https://openalex.org/C188027245","wikidata":"https://www.wikidata.org/wiki/Q750446","display_name":"Polymer chemistry","level":1,"score":0.1713525354862213},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.12914809584617615},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.066433846950531},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.06118890643119812}],"mesh":[],"locations_count":5,"locations":[{"id":"doi:10.1039/c4tb00885e","doi":"https://doi.org/10.1039/c4tb00885e","is_oa":true,"landing_page_url":"https://doi.org/10.1039/c4tb00885e","pdf_url":"https://pubs.rsc.org/en/content/articlepdf/2015/tb/c4tb00885e","source":{"id":"https://openalex.org/S2479884170","display_name":"Journal of Materials Chemistry B","issn_l":"2050-750X","issn":["2050-750X","2050-7518"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320556","host_organization_name":"Royal Society of Chemistry","host_organization_lineage":["https://openalex.org/P4310320556"],"host_organization_lineage_names":["Royal Society of Chemistry"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Materials Chemistry B","raw_type":"journal-article"},{"id":"pmid:32262378","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/32262378","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of materials chemistry. B","raw_type":"Journal Article"},{"id":"pmh:oai:cris.maastrichtuniversity.nl:openaire/4cf471de-36bd-4d6e-b010-df1d0ab6865e","doi":null,"is_oa":true,"landing_page_url":"https://cris.maastrichtuniversity.nl/en/publications/4cf471de-36bd-4d6e-b010-df1d0ab6865e","pdf_url":null,"source":{"id":"https://openalex.org/S4306402616","display_name":"Research Publications (Maastricht University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I34352273","host_organization_name":"Maastricht University","host_organization_lineage":["https://openalex.org/I34352273"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Neves, S C, Gomes, D B, Sousa, A, Bidarra, S J, Petrini, P, Moroni, L, Barrias, C C & Granja, P L 2015, 'Biofunctionalized pectin hydrogels as 3D cellular microenvironments', Journal of Materials Chemistry. B, Materials for Biology and Medicine, vol. 3, no. 10, pp. 2096-2108. https://doi.org/10.1039/c4tb00885e","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:re.public.polimi.it:11311/971650","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/11311/971650","pdf_url":"https://re.public.polimi.it/bitstream/11311/971650/4/NevesAuthorversion.pdf","source":{"id":"https://openalex.org/S4306400312","display_name":"Virtual Community of Pathological Anatomy (University of Castilla La Mancha)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I79189158","host_organization_name":"University of Castilla-La Mancha","host_organization_lineage":["https://openalex.org/I79189158"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:um:oai:cris.maastrichtuniversity.nl:publications/4cf471de-36bd-4d6e-b010-df1d0ab6865e","doi":null,"is_oa":true,"landing_page_url":"https://cris.maastrichtuniversity.nl/en/publications/4cf471de-36bd-4d6e-b010-df1d0ab6865e","pdf_url":null,"source":{"id":"https://openalex.org/S4306402616","display_name":"Research Publications (Maastricht University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I34352273","host_organization_name":"Maastricht University","host_organization_lineage":["https://openalex.org/I34352273"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Journal of Materials Chemistry. B, Materials for Biology and Medicine, 3(10), 2096 - 2108. Royal Society of Chemistry","raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":{"id":"doi:10.1039/c4tb00885e","doi":"https://doi.org/10.1039/c4tb00885e","is_oa":true,"landing_page_url":"https://doi.org/10.1039/c4tb00885e","pdf_url":"https://pubs.rsc.org/en/content/articlepdf/2015/tb/c4tb00885e","source":{"id":"https://openalex.org/S2479884170","display_name":"Journal of Materials Chemistry B","issn_l":"2050-750X","issn":["2050-750X","2050-7518"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320556","host_organization_name":"Royal Society of Chemistry","host_organization_lineage":["https://openalex.org/P4310320556"],"host_organization_lineage_names":["Royal Society of Chemistry"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Materials Chemistry B","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.4000000059604645}],"study_designs":[],"awards":[{"id":"https://openalex.org/G1167214205","display_name":null,"funder_award_id":"COMPETE","funder_id":"https://openalex.org/F4320335322","funder_display_name":"European Regional Development Fund"},{"id":"https://openalex.org/G1510953964","display_name":"Projecto Estrat\u00e9gico - LA 2 - 2011-2012","funder_award_id":"PEst-C/SAU/LA0002/2011","funder_id":"https://openalex.org/F4320334779","funder_display_name":"Funda\u00e7\u00e3o para a Ci\u00eancia e a Tecnologia"},{"id":"https://openalex.org/G1568799903","display_name":"ARTIFICIAL EXTRACELLULAR MATRIX-LIKE MATRICES AS 3D IN VITRO MODELS TO INVESTIGATE THE ROLE OF THE MICROENVIRONMENT IN CANCER METASTISATION","funder_award_id":"SFRH/BPD/80571/2011","funder_id":"https://openalex.org/F4320334779","funder_display_name":"Funda\u00e7\u00e3o para a Ci\u00eancia e a Tecnologia"},{"id":"https://openalex.org/G1578237752","display_name":null,"funder_award_id":"COMPETE","funder_id":"https://openalex.org/F4320334779","funder_display_name":"Funda\u00e7\u00e3o para a Ci\u00eancia e a Tecnologia"},{"id":"https://openalex.org/G3628287374","display_name":null,"funder_award_id":"Ci\u00eancia 2008","funder_id":"https://openalex.org/F4320334779","funder_display_name":"Funda\u00e7\u00e3o para a Ci\u00eancia e a Tecnologia"},{"id":"https://openalex.org/G3790458332","display_name":"3D HYBRID CONSTRUCTS FOR TISSUE ENGINEERING - COMBINING FUNCTIONALIZED HYDROGELS WITH SURFACE-STRUCTURED RAPID PROTOTYPED SCAFFOLDS","funder_award_id":"SFRH/BD/76995/2011","funder_id":"https://openalex.org/F4320334779","funder_display_name":"Funda\u00e7\u00e3o para a Ci\u00eancia e a Tecnologia"},{"id":"https://openalex.org/G5044206991","display_name":null,"funder_award_id":"PEst-C/SAU/LA0002/2011","funder_id":"https://openalex.org/F4320335322","funder_display_name":"European Regional Development Fund"},{"id":"https://openalex.org/G826566410","display_name":"BIOPRINTED CELULLARIZED HYDROGELS FOR IN SITU SKIN REGENERATION","funder_award_id":"SFRH/BPD/90047/2012","funder_id":"https://openalex.org/F4320334779","funder_display_name":"Funda\u00e7\u00e3o para a Ci\u00eancia e a Tecnologia"}],"funders":[{"id":"https://openalex.org/F4320334779","display_name":"Funda\u00e7\u00e3o para a Ci\u00eancia e a Tecnologia","ror":"https://ror.org/00snfqn58"},{"id":"https://openalex.org/F4320335322","display_name":"European Regional Development Fund","ror":"https://ror.org/00k4n6c32"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2129199903.pdf","grobid_xml":"https://content.openalex.org/works/W2129199903.grobid-xml"},"referenced_works_count":55,"referenced_works":["https://openalex.org/W152547734","https://openalex.org/W297918892","https://openalex.org/W577424926","https://openalex.org/W636469369","https://openalex.org/W1542490819","https://openalex.org/W1907575281","https://openalex.org/W1968694386","https://openalex.org/W1970576706","https://openalex.org/W1971500643","https://openalex.org/W1974200089","https://openalex.org/W1975484116","https://openalex.org/W1976230147","https://openalex.org/W1977708448","https://openalex.org/W1980631211","https://openalex.org/W1981626311","https://openalex.org/W1987523658","https://openalex.org/W1999382841","https://openalex.org/W2001902689","https://openalex.org/W2003194781","https://openalex.org/W2014327439","https://openalex.org/W2018636080","https://openalex.org/W2020795728","https://openalex.org/W2023962609","https://openalex.org/W2024592842","https://openalex.org/W2031718324","https://openalex.org/W2034046772","https://openalex.org/W2039514563","https://openalex.org/W2042380170","https://openalex.org/W2043990601","https://openalex.org/W2055455602","https://openalex.org/W2058637438","https://openalex.org/W2058808643","https://openalex.org/W2062351837","https://openalex.org/W2063753069","https://openalex.org/W2069937597","https://openalex.org/W2071222724","https://openalex.org/W2072054293","https://openalex.org/W2076076808","https://openalex.org/W2080226819","https://openalex.org/W2080768947","https://openalex.org/W2081172134","https://openalex.org/W2084610464","https://openalex.org/W2087787344","https://openalex.org/W2094264163","https://openalex.org/W2101981433","https://openalex.org/W2104046482","https://openalex.org/W2105127765","https://openalex.org/W2105300288","https://openalex.org/W2108379632","https://openalex.org/W2113313728","https://openalex.org/W2113547540","https://openalex.org/W2152676524","https://openalex.org/W2155097867","https://openalex.org/W2171182378","https://openalex.org/W2319375857"],"related_works":["https://openalex.org/W3183274177","https://openalex.org/W2779718946","https://openalex.org/W4293194386","https://openalex.org/W1968694386","https://openalex.org/W2920846117","https://openalex.org/W2945404263","https://openalex.org/W3111863644","https://openalex.org/W7020000054","https://openalex.org/W4417048625","https://openalex.org/W2058410877"],"abstract_inverted_index":{"In":[0,124],"situ-forming":[1],"hydrogels":[2,97,128,153],"of":[3,12,57,62,98,146,169,177],"pectin,":[4],"a":[5,45,76],"polysaccharide":[6],"present":[7],"in":[8,149,183],"the":[9,30,55,63,141,158,166,182],"cell":[10,34],"wall":[11],"higher":[13],"plants,":[14],"were":[15,154],"prepared":[16],"using":[17],"an":[18,174],"internal":[19],"ionotropic":[20],"gelation":[21,81],"strategy":[22],"based":[23],"on":[24],"calcium":[25],"carbonate/d-glucono-\u03b4-lactone,":[26],"and":[27,47,60,86,95,102,107,122,138,190],"explored":[28],"for":[29,110,187],"first":[31],"time":[32],"as":[33],"delivery":[35],"vehicles.":[36],"Since":[37],"no":[38],"ultrapure":[39],"pectins":[40],"are":[41],"commercially":[42],"available":[43],"yet,":[44],"simple":[46],"efficient":[48],"purification":[49],"method":[50],"was":[51,69,82],"established,":[52],"effectively":[53],"reducing":[54],"levels":[56],"proteins,":[58],"polyphenols":[59],"endotoxins":[61],"raw":[64],"pectin.":[65],"The":[66],"purified":[67],"pectin":[68,117,152],"then":[70],"functionalized":[71],"by":[72,84],"carbodiimide":[73],"chemistry":[74],"with":[75],"cell-adhesive":[77],"peptide":[78],"(RGD).":[79],"Its":[80],"analyzed":[83],"rheometry":[85],"optimized.":[87],"Human":[88],"mesenchymal":[89],"stem":[90],"cells":[91,119],"embedded":[92],"within":[93,126],"unmodified":[94,116],"RGD-pectin":[96,127],"different":[99],"viscoelasticities":[100],"(1.5":[101],"2.5":[103],"wt%)":[104],"remained":[105,120],"viable":[106],"metabolically":[108],"active":[109],"up":[111],"to":[112],"14":[113],"days.":[114],"On":[115],"hydrogels,":[118,171],"isolated":[121],"round-shaped.":[123],"contrast,":[125],"they":[129],"elongated,":[130],"spread,":[131],"established":[132],"cell-to-cell":[133],"contacts,":[134],"produced":[135],"extracellular":[136],"matrix,":[137],"migrated":[139],"outwards":[140],"hydrogels.":[142,161],"After":[143],"7":[144],"days":[145],"subcutaneous":[147],"implantation":[148],"mice,":[150],"acellular":[151],"considerably":[155],"degraded,":[156],"particularly":[157],"1.5":[159],"wt%":[160],"Altogether,":[162],"these":[163],"findings":[164],"show":[165],"great":[167],"potential":[168],"pectin-based":[170],"which":[172],"combine":[173],"interesting":[175],"set":[176],"easily":[178],"tunable":[179],"properties,":[180],"including":[181],"vivo":[184],"degradation":[185],"profile,":[186],"tissue":[188],"engineering":[189],"regenerative":[191],"medicine.":[192]},"counts_by_year":[{"year":2026,"cited_by_count":6},{"year":2025,"cited_by_count":4},{"year":2024,"cited_by_count":8},{"year":2023,"cited_by_count":12},{"year":2022,"cited_by_count":7},{"year":2021,"cited_by_count":12},{"year":2020,"cited_by_count":20},{"year":2019,"cited_by_count":6},{"year":2018,"cited_by_count":10},{"year":2017,"cited_by_count":13},{"year":2016,"cited_by_count":5},{"year":2015,"cited_by_count":2}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2016-06-24T00:00:00"}