{"id":"https://openalex.org/W2129199496","doi":null,"title":"Apoptotic neutrophils enhance the immune response against Mycobacterium tuberculosis","display_name":"Apoptotic neutrophils enhance the immune response against Mycobacterium tuberculosis","publication_year":2009,"publication_date":"2009-01-01","ids":{"openalex":"https://openalex.org/W2129199496","mag":"2129199496"},"language":"en","primary_location":{"id":"pmh:oai:DiVA.org:liu-51467","doi":null,"is_oa":true,"landing_page_url":"http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-51467","pdf_url":null,"source":{"id":"https://openalex.org/S4306401559","display_name":"KTH Publication Database DiVA (KTH Royal Institute of Technology)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I86987016","host_organization_name":"KTH Royal Institute of Technology","host_organization_lineage":["https://openalex.org/I86987016"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"info:eu-repo/semantics/doctoralThesis"},"volume":null,"type":"dissertation","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-51467","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5004909473","display_name":"Alexander Persson","orcid":"https://orcid.org/0000-0002-9631-2169","observed_orcids":["https://orcid.org/0000-0002-9631-2169"]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Alexander Persson","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-9631-2169","affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":["https://openalex.org/A5004909473"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10038","display_name":"Tuberculosis Research and Epidemiology","score":0.9789999723434448,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10038","display_name":"Tuberculosis Research and Epidemiology","score":0.9789999723434448,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12672","display_name":"Phagocytosis and Immune Regulation","score":0.010900000110268593,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T13410","display_name":"Immune responses and vaccinations","score":0.005200000014156103,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/mycobacterium-tuberculosis","display_name":"Mycobacterium tuberculosis","score":0.9660000205039978},{"id":"https://openalex.org/keywords/tuberculosis","display_name":"tuberculosis","score":0.7440000176429749},{"id":"https://openalex.org/keywords/neutrophil-apoptosis","display_name":"neutrophil apoptosis","score":0.9599999785423279},{"id":"https://openalex.org/keywords/innate-immunity","display_name":"innate immunity","score":0.6980000138282776},{"id":"https://openalex.org/keywords/alveolar-macrophages","display_name":"alveolar macrophages","score":0.8700000047683716},{"id":"https://openalex.org/keywords/granuloma","display_name":"granuloma","score":0.6570000052452087},{"id":"https://openalex.org/keywords/hsp72","display_name":"HSP72","score":0.8159999847412109},{"id":"https://openalex.org/keywords/dendritic-cell-maturation","display_name":"dendritic cell maturation","score":0.9610000252723694},{"id":"https://openalex.org/keywords/t-cell-activation","display_name":"T cell activation","score":0.4659999907016754},{"id":"https://openalex.org/keywords/complement-mediated-phagocytosis","display_name":"complement-mediated phagocytosis","score":0.7289999723434448},{"id":"https://openalex.org/keywords/akt-signaling","display_name":"Akt signaling","score":0.5270000100135803},{"id":"https://openalex.org/keywords/intracellular-killing","display_name":"intracellular killing","score":0.4099999964237213},{"id":"https://openalex.org/keywords/hiv-tb-co-infection","display_name":"HIV/TB coinfection","score":0.6110000014305115}],"concepts":[{"id":"https://openalex.org/C160448771","wikidata":"https://www.wikidata.org/wiki/Q184726","display_name":"Phagocytosis","level":2,"score":0.759194552898407},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.7357221245765686},{"id":"https://openalex.org/C2777975735","wikidata":"https://www.wikidata.org/wiki/Q130971","display_name":"Mycobacterium tuberculosis","level":3,"score":0.6924486756324768},{"id":"https://openalex.org/C2781069245","wikidata":"https://www.wikidata.org/wiki/Q12204","display_name":"Tuberculosis","level":2,"score":0.6796755790710449},{"id":"https://openalex.org/C8891405","wikidata":"https://www.wikidata.org/wiki/Q1059","display_name":"Immune system","level":2,"score":0.669963538646698},{"id":"https://openalex.org/C136449434","wikidata":"https://www.wikidata.org/wiki/Q428253","display_name":"Innate immune system","level":3,"score":0.5680899024009705},{"id":"https://openalex.org/C2779244956","wikidata":"https://www.wikidata.org/wiki/Q184204","display_name":"Macrophage","level":3,"score":0.523044228553772},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.5066383481025696},{"id":"https://openalex.org/C161478664","wikidata":"https://www.wikidata.org/wiki/Q901955","display_name":"Phagosome","level":3,"score":0.47947773337364197},{"id":"https://openalex.org/C2779341262","wikidata":"https://www.wikidata.org/wiki/Q182581","display_name":"Immunity","level":3,"score":0.4769410192966461},{"id":"https://openalex.org/C2776914184","wikidata":"https://www.wikidata.org/wiki/Q101991","display_name":"Inflammation","level":2,"score":0.47631964087486267},{"id":"https://openalex.org/C89423630","wikidata":"https://www.wikidata.org/wiki/Q7193","display_name":"Microbiology","level":1,"score":0.4444098472595215},{"id":"https://openalex.org/C2777700362","wikidata":"https://www.wikidata.org/wiki/Q107647","display_name":"Phagocyte","level":3,"score":0.4245016872882843},{"id":"https://openalex.org/C2780140890","wikidata":"https://www.wikidata.org/wiki/Q1129338","display_name":"Granuloma","level":2,"score":0.42063260078430176},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.3159991502761841},{"id":"https://openalex.org/C202751555","wikidata":"https://www.wikidata.org/wiki/Q221681","display_name":"In vitro","level":2,"score":0.07458561658859253},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.06496423482894897},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0}],"mesh":[],"locations_count":2,"locations":[{"id":"pmh:oai:DiVA.org:liu-51467","doi":null,"is_oa":true,"landing_page_url":"http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-51467","pdf_url":null,"source":{"id":"https://openalex.org/S4306401559","display_name":"KTH Publication Database DiVA (KTH Royal Institute of Technology)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I86987016","host_organization_name":"KTH Royal Institute of Technology","host_organization_lineage":["https://openalex.org/I86987016"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"info:eu-repo/semantics/doctoralThesis"},{"id":"mag:2129199496","doi":null,"is_oa":false,"landing_page_url":"http://liu.diva-portal.org/smash/get/diva2:275220/FULLTEXT02.pdf","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":{"id":"pmh:oai:DiVA.org:liu-51467","doi":null,"is_oa":true,"landing_page_url":"http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-51467","pdf_url":null,"source":{"id":"https://openalex.org/S4306401559","display_name":"KTH Publication Database DiVA (KTH Royal Institute of Technology)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I86987016","host_organization_name":"KTH Royal Institute of Technology","host_organization_lineage":["https://openalex.org/I86987016"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"info:eu-repo/semantics/doctoralThesis"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.98580002784729,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":250,"referenced_works":["https://openalex.org/W40856236","https://openalex.org/W318591687","https://openalex.org/W1479707731","https://openalex.org/W1483175931","https://openalex.org/W1486002030","https://openalex.org/W1492302205","https://openalex.org/W1515599953","https://openalex.org/W1529674879","https://openalex.org/W1537427751","https://openalex.org/W1538447709","https://openalex.org/W1543854090","https://openalex.org/W1545857506","https://openalex.org/W1548326502","https://openalex.org/W1549438168","https://openalex.org/W1553697637","https://openalex.org/W1557239654","https://openalex.org/W1561591381","https://openalex.org/W1569629748","https://openalex.org/W1572384585","https://openalex.org/W1573103899","https://openalex.org/W1579749431","https://openalex.org/W1589415602","https://openalex.org/W1593392123","https://openalex.org/W1595587273","https://openalex.org/W1602791306","https://openalex.org/W1603820262","https://openalex.org/W1610241671","https://openalex.org/W1655860314","https://openalex.org/W1661544713","https://openalex.org/W1670406330","https://openalex.org/W1736132406","https://openalex.org/W1744321256","https://openalex.org/W1811586967","https://openalex.org/W1818791232","https://openalex.org/W1864461701","https://openalex.org/W1864777644","https://openalex.org/W1883324033","https://openalex.org/W1900378797","https://openalex.org/W1903734129","https://openalex.org/W1927671826","https://openalex.org/W1933350751","https://openalex.org/W1940692702","https://openalex.org/W1941961496","https://openalex.org/W1942966726","https://openalex.org/W1953221463","https://openalex.org/W1964572598","https://openalex.org/W1966763839","https://openalex.org/W1968736434","https://openalex.org/W1971756409","https://openalex.org/W1973190361","https://openalex.org/W1973364072","https://openalex.org/W1974541422","https://openalex.org/W1981693533","https://openalex.org/W1982878961","https://openalex.org/W1989319078","https://openalex.org/W1989966995","https://openalex.org/W1990772742","https://openalex.org/W1991233072","https://openalex.org/W1992103602","https://openalex.org/W1992823344","https://openalex.org/W1993276940","https://openalex.org/W1995170943","https://openalex.org/W1995744610","https://openalex.org/W1996512088","https://openalex.org/W1997708855","https://openalex.org/W1999512658","https://openalex.org/W2001015172","https://openalex.org/W2002503549","https://openalex.org/W2004465286","https://openalex.org/W2004694654","https://openalex.org/W2004773897","https://openalex.org/W2008202400","https://openalex.org/W2008513611","https://openalex.org/W2012416622","https://openalex.org/W2015015357","https://openalex.org/W2016255773","https://openalex.org/W2017090013","https://openalex.org/W2017102177","https://openalex.org/W2018840055","https://openalex.org/W2018917333","https://openalex.org/W2019255399","https://openalex.org/W2020134925","https://openalex.org/W2020588519","https://openalex.org/W2021984884","https://openalex.org/W2022159086","https://openalex.org/W2023750468","https://openalex.org/W2024105041","https://openalex.org/W2024306318","https://openalex.org/W2027657858","https://openalex.org/W2029948625","https://openalex.org/W2029971722","https://openalex.org/W2034530432","https://openalex.org/W2034915619","https://openalex.org/W2035531438","https://openalex.org/W2035961359","https://openalex.org/W2036420717","https://openalex.org/W2036635548","https://openalex.org/W2038048357","https://openalex.org/W2039181024","https://openalex.org/W2039949492","https://openalex.org/W2042561434","https://openalex.org/W2043310375","https://openalex.org/W2045096944","https://openalex.org/W2045362817","https://openalex.org/W2046299226","https://openalex.org/W2048597976","https://openalex.org/W2050063932","https://openalex.org/W2052853635","https://openalex.org/W2054065314","https://openalex.org/W2054286408","https://openalex.org/W2054941139","https://openalex.org/W2055472767","https://openalex.org/W2055494323","https://openalex.org/W2056912931","https://openalex.org/W2060098138","https://openalex.org/W2061170463","https://openalex.org/W2063210473","https://openalex.org/W2064964564","https://openalex.org/W2065076024","https://openalex.org/W2065791817","https://openalex.org/W2066135800","https://openalex.org/W2066823704","https://openalex.org/W2068101083","https://openalex.org/W2068812138","https://openalex.org/W2071449756","https://openalex.org/W2072796605","https://openalex.org/W2075836508","https://openalex.org/W2076174684","https://openalex.org/W2076296181","https://openalex.org/W2076631817","https://openalex.org/W2079892707","https://openalex.org/W2081286173","https://openalex.org/W2082476464","https://openalex.org/W2085442635","https://openalex.org/W2085728531","https://openalex.org/W2092006466","https://openalex.org/W2094605832","https://openalex.org/W2095022409","https://openalex.org/W2095472825","https://openalex.org/W2095537212","https://openalex.org/W2097852076","https://openalex.org/W2098084836","https://openalex.org/W2098891573","https://openalex.org/W2098942474","https://openalex.org/W2099288361","https://openalex.org/W2099613681","https://openalex.org/W2100872199","https://openalex.org/W2100915449","https://openalex.org/W2102723961","https://openalex.org/W2103533975","https://openalex.org/W2103870285","https://openalex.org/W2104941073","https://openalex.org/W2105570009","https://openalex.org/W2105952229","https://openalex.org/W2107417881","https://openalex.org/W2107552777","https://openalex.org/W2107552851","https://openalex.org/W2107721036","https://openalex.org/W2108987359","https://openalex.org/W2109484445","https://openalex.org/W2110530857","https://openalex.org/W2110760006","https://openalex.org/W2111220263","https://openalex.org/W2111462867","https://openalex.org/W2112645925","https://openalex.org/W2113120391","https://openalex.org/W2113265821","https://openalex.org/W2113990199","https://openalex.org/W2114220827","https://openalex.org/W2117667204","https://openalex.org/W2118921720","https://openalex.org/W2119556176","https://openalex.org/W2119724532","https://openalex.org/W2120222116","https://openalex.org/W2120326154","https://openalex.org/W2121449107","https://openalex.org/W2121499583","https://openalex.org/W2121652085","https://openalex.org/W2123084649","https://openalex.org/W2123450457","https://openalex.org/W2123888778","https://openalex.org/W2124580054","https://openalex.org/W2125762027","https://openalex.org/W2126245681","https://openalex.org/W2126261381","https://openalex.org/W2127491513","https://openalex.org/W2127747031","https://openalex.org/W2129159114","https://openalex.org/W2130046741","https://openalex.org/W2130968927","https://openalex.org/W2131523916","https://openalex.org/W2133685180","https://openalex.org/W2134101952","https://openalex.org/W2134582553","https://openalex.org/W2134768631","https://openalex.org/W2135116662","https://openalex.org/W2135394011","https://openalex.org/W2135437388","https://openalex.org/W2135468069","https://openalex.org/W2135721651","https://openalex.org/W2136501069","https://openalex.org/W2136886125","https://openalex.org/W2138989146","https://openalex.org/W2139492141","https://openalex.org/W2139654854","https://openalex.org/W2139738983","https://openalex.org/W2141912213","https://openalex.org/W2142487484","https://openalex.org/W2144652377","https://openalex.org/W2147251439","https://openalex.org/W2147379467","https://openalex.org/W2147698308","https://openalex.org/W2148599087","https://openalex.org/W2149200346","https://openalex.org/W2151612737","https://openalex.org/W2151738661","https://openalex.org/W2152937186","https://openalex.org/W2153454088","https://openalex.org/W2154361055","https://openalex.org/W2155049659","https://openalex.org/W2155099281","https://openalex.org/W2155474314","https://openalex.org/W2157559696","https://openalex.org/W2157685329","https://openalex.org/W2157737997","https://openalex.org/W2160025165","https://openalex.org/W2160649336","https://openalex.org/W2161489704","https://openalex.org/W2161592441","https://openalex.org/W2161878252","https://openalex.org/W2162644900","https://openalex.org/W2163034757","https://openalex.org/W2163188970","https://openalex.org/W2164474259","https://openalex.org/W2164842550","https://openalex.org/W2165027127","https://openalex.org/W2165201729","https://openalex.org/W2165721689","https://openalex.org/W2166305071","https://openalex.org/W2168717822","https://openalex.org/W2170363109","https://openalex.org/W2252690754","https://openalex.org/W2264085200","https://openalex.org/W2314996784","https://openalex.org/W2330109819","https://openalex.org/W2344703981","https://openalex.org/W2405245954","https://openalex.org/W4313333717","https://openalex.org/W4313376988","https://openalex.org/W4313422336"],"related_works":["https://openalex.org/W7095865329","https://openalex.org/W2013322108","https://openalex.org/W1993276940","https://openalex.org/W2039075220","https://openalex.org/W2111462867","https://openalex.org/W2010819095","https://openalex.org/W3197118013","https://openalex.org/W2954661847","https://openalex.org/W3182728948","https://openalex.org/W2362835022"],"abstract_inverted_index":{"Mycobacterium":[0],"tuberculosis":[1,22,63],"(Mtb)":[2],"is":[3,23,71,167,387],"the":[4,19,46,54,73,76,95,99,107,116,121,136,176,215,234,240,267,271,298,313,342,353,392,418,422],"causative":[5],"agent":[6],"of":[7,18,91,112,120,155,164,180,233,282,297,334,344,358,391,405],"tuberculosis,":[8],"a":[9,103,131,153,201,210,372,388,415],"disease":[10],"that":[11,133,161,223,237,290,300,363,383],"for":[12,37,69,341],"years":[13],"was":[14,228,263,307],"considered":[15],"to":[16,101,114,124,213,242,265,327,370,376],"belong":[17],"past,":[20],"but":[21,89,258,407],"back":[24],"causing":[25],"over":[26],"2":[27],"million":[28],"deaths":[29],"per":[30],"year.":[31],"The":[32,65,110],"infection":[33,47,117],"can":[34,44,142,320],"be":[35,173],"dormant":[36],"decades":[38],"and":[39,129,145,186,195,204,217,330,356,421],"an":[40,59],"active":[41,51,149],"immune":[42,122,411,424],"response":[43,171,355,394,425],"prevent":[45],"from":[48,312],"progressing":[49],"into":[50,75,148],"disease.":[52,150],"However,":[53,151],"HIV/AIDS":[55],"epidemic":[56],"has":[57],"caused":[58],"alarming":[60],"rise":[61],"in":[62,105,226,245,256,270,322],"cases.":[64],"main":[66],"infectious":[67],"route":[68],"Mtb":[70,83,97,141,165,190,238,262,326],"through":[72],"airways":[74],"lungs,":[77],"where":[78],"they":[79],"encounter":[80],"alveolar":[81],"macrophages.":[82,188,287],"are":[84,205,339],"phagocytosed":[85,325],"by":[86,175,207,309],"these":[87],"macrophages,":[88],"instead":[90],"being":[92],"killing":[93,333],"within":[94],"phagosome,":[96],"modulates":[98],"cell":[100],"become":[102,193],"host":[104],"which":[106],"bacteria":[108],"thrive.":[109],"lack":[111],"capacity":[113,241],"eradicate":[115],"stimulate":[118],"cells":[119,338,369],"system":[123],"gather":[125],"around":[126],"infected":[127,384],"macrophages":[128,192,299,329],"form":[130],"granuloma":[132],"walls":[134],"off":[135],"infection.":[137],"Within":[138],"this":[139,305],"granuloma,":[140],"wait":[143],"silently":[144],"later":[146],"progress":[147],"only":[152,401],"fraction":[154],"exposed":[156],"individuals":[157],"develop":[158],"disease,":[159],"indicating":[160,236],"initial":[162],"eradication":[163],"infections":[166],"possible.":[168],"Such":[169],"immediate":[170],"must":[172],"directed":[174],"innate":[177,420],"immunity":[178],"comprised":[179],"phagocytes":[181,274],"such":[182,253],"as":[183,254],"neutrophils":[184],"(PMNs)":[185],"non-activated":[187],"Upon":[189],"infection,":[191],"anergic":[194],"PMNs":[196,199,227,285,293,319,351,366,386,399],"enter":[197,371],"apoptosis.":[198],"have":[200,239],"short":[202],"lifespan":[203],"cleared":[206,301],"neighbouring":[208],"phagocytes,":[209],"mechanism":[211],"described":[212],"resolve":[214],"inflammation":[216],"modulate":[218,409],"tissue":[219],"regeneration.":[220],"We":[221,288,361,381],"found":[222,289,362],"Mtb-induced":[224,283,291,314,349,364],"apoptosis":[225,244],"not":[229,400],"dependent":[230],"on":[231],"phagocytosis":[232,249],"bacteria,":[235],"induce":[243,250],"multiple":[246],"PMNs.":[247,316],"Complement-mediated":[248],"survival":[251],"signals":[252],"Akt":[255],"PMNs,":[257],"despite":[259],"this,":[260],"complement-opsonized":[261],"able":[264,375],"override":[266],"anti-apoptotic":[268],"activation":[269,296,306],"cells.":[272,360],"Since":[273,336],"clear":[275],"apoptotic":[276,284,292,315,318,350,365,385],"cells,":[277,412],"we":[278,346],"investigated":[279,347],"how":[280],"clearance":[281],"affected":[286,352],"inflicted":[294],"pro-inflammatory":[295],"them.":[302],"In":[303],"addition,":[304],"mediated":[308],"Hsp72":[310],"released":[311],"Furthermore,":[317],"work":[321],"synergy":[323],"with":[324,429],"activate":[328,377],"enhance":[331],"intracellular":[332],"Mtb.":[335,430],"dendritic":[337,359,368],"important":[340],"regulation":[343],"immunity,":[345],"whether":[348],"inflammatory":[354,393],"maturation":[357],"trigger":[367],"mature":[373],"state":[374],"na\u00efve":[378],"T-cell":[379],"proliferation.":[380],"propose":[382],"potent":[389],"activator":[390],"during":[395,426],"infections.":[396],"Taken":[397],"together,":[398],"kill":[402],"their":[403],"share":[404],"pathogens":[406],"also":[408],"other":[410],"thereby":[413],"forming":[414],"link":[416],"between":[417],"early":[419],"adaptive":[423],"microbial":[427],"challenge":[428]},"counts_by_year":[],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}
