{"id":"https://openalex.org/W2129136659","doi":"https://doi.org/10.1523/jneurosci.19-19-08623.1999","title":"Cortical Involvement in the Induction, But Not Expression, of Thalamic Plasticity","display_name":"Cortical Involvement in the Induction, But Not Expression, of Thalamic Plasticity","publication_year":1999,"publication_date":"1999-10-01","ids":{"openalex":"https://openalex.org/W2129136659","doi":"https://doi.org/10.1523/jneurosci.19-19-08623.1999","mag":"2129136659","pmid":"https://pubmed.ncbi.nlm.nih.gov/10493762","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/6783037"},"language":"en","primary_location":{"id":"doi:10.1523/jneurosci.19-19-08623.1999","doi":"https://doi.org/10.1523/jneurosci.19-19-08623.1999","is_oa":true,"landing_page_url":"https://doi.org/10.1523/jneurosci.19-19-08623.1999","pdf_url":"https://www.jneurosci.org/content/jneuro/19/19/8623.full.pdf","source":{"id":"https://openalex.org/S5555990","display_name":"Journal of Neuroscience","issn_l":"0270-6474","issn":["0270-6474","1529-2401"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-b","doyens","jufo-3","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319739","host_organization_name":"Society for Neuroscience","host_organization_lineage":["https://openalex.org/P4310319739"],"host_organization_lineage_names":["Society for Neuroscience"],"type":"journal"},"license":"cc-by-nc-sa","license_id":"https://openalex.org/licenses/cc-by-nc-sa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of Neuroscience","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://www.jneurosci.org/content/jneuro/19/19/8623.full.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5009971978","display_name":"Jayson Lee Parker","orcid":"https://orcid.org/0000-0002-5890-6169","observed_orcids":["https://orcid.org/0000-0002-5890-6169"]},"institutions":[{"id":"https://openalex.org/I185261750","display_name":"University of Toronto","ror":"https://ror.org/03dbr7087","country_code":"CA","type":"education","lineage":["https://openalex.org/I185261750"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Jayson L. Parker","raw_affiliation_strings":["University of Toronto, Department of Physiology, Toronto, Ontario M5S 1A8, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Toronto, Department of Physiology, Toronto, Ontario M5S 1A8, Canada","institution_ids":["https://openalex.org/I185261750"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5021176150","display_name":"Jonathan O. Dostrovsky","orcid":"https://orcid.org/0000-0002-2395-6713","observed_orcids":["https://orcid.org/0000-0002-2395-6713"]},"institutions":[{"id":"https://openalex.org/I185261750","display_name":"University of Toronto","ror":"https://ror.org/03dbr7087","country_code":"CA","type":"education","lineage":["https://openalex.org/I185261750"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Jonathan O. Dostrovsky","raw_affiliation_strings":["University of Toronto, Department of Physiology, Toronto, Ontario M5S 1A8, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Toronto, Department of Physiology, Toronto, Ontario M5S 1A8, Canada","institution_ids":["https://openalex.org/I185261750"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I185261750"],"apc_list":null,"apc_paid":null,"fwci":1.4938,"has_fulltext":true,"cited_by_count":37,"citation_normalized_percentile":{"value":0.81515728,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":96},"biblio":{"volume":"19","issue":"19","first_page":"8623","last_page":"8629"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10914","display_name":"Tactile and Sensory Interactions","score":0.9907000064849854,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10914","display_name":"Tactile and Sensory Interactions","score":0.9907000064849854,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10581","display_name":"Neural dynamics and brain function","score":0.0017000000225380063,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10982","display_name":"Motor Control and Adaptation","score":0.0013000000035390258,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/somatosensory-cortex","display_name":"somatosensory cortex","score":0.953000009059906},{"id":"https://openalex.org/keywords/nucleus-gracilis","display_name":"nucleus gracilis","score":0.8259999752044678},{"id":"https://openalex.org/keywords/cortical-lesions","display_name":"cortical lesions","score":0.5419999957084656},{"id":"https://openalex.org/keywords/somatosensory-thalamus","display_name":"somatosensory thalamus","score":0.8289999961853027},{"id":"https://openalex.org/keywords/thalamocortical-interactions","display_name":"thalamocortical interactions","score":0.5299999713897705}],"concepts":[{"id":"https://openalex.org/C172497186","wikidata":"https://www.wikidata.org/wiki/Q328835","display_name":"Somatosensory system","level":2,"score":0.9117673635482788},{"id":"https://openalex.org/C2779246727","wikidata":"https://www.wikidata.org/wiki/Q184215","display_name":"Thalamus","level":2,"score":0.8385447263717651},{"id":"https://openalex.org/C51738704","wikidata":"https://www.wikidata.org/wiki/Q5766112","display_name":"Hindlimb","level":2,"score":0.804390013217926},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.6776256561279297},{"id":"https://openalex.org/C94487597","wikidata":"https://www.wikidata.org/wiki/Q11101","display_name":"Sensory system","level":2,"score":0.5755208730697632},{"id":"https://openalex.org/C2778646069","wikidata":"https://www.wikidata.org/wiki/Q5468632","display_name":"Forelimb","level":2,"score":0.5483912825584412},{"id":"https://openalex.org/C2777348757","wikidata":"https://www.wikidata.org/wiki/Q2346577","display_name":"Cortex (anatomy)","level":2,"score":0.5316845774650574},{"id":"https://openalex.org/C2779508121","wikidata":"https://www.wikidata.org/wiki/Q7451122","display_name":"Sensory cortex","level":3,"score":0.5258629322052002},{"id":"https://openalex.org/C105702510","wikidata":"https://www.wikidata.org/wiki/Q514","display_name":"Anatomy","level":1,"score":0.5171850919723511},{"id":"https://openalex.org/C47611674","wikidata":"https://www.wikidata.org/wiki/Q849491","display_name":"Neuroplasticity","level":2,"score":0.44783616065979004},{"id":"https://openalex.org/C2781156865","wikidata":"https://www.wikidata.org/wiki/Q827023","display_name":"Lesion","level":2,"score":0.42946910858154297},{"id":"https://openalex.org/C2780723820","wikidata":"https://www.wikidata.org/wiki/Q1934178","display_name":"Nucleus","level":2,"score":0.4219599962234497},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.3866533041000366},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.30256032943725586},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.15184250473976135}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001931","descriptor_name":"Brain Mapping","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D002540","descriptor_name":"Cerebral Cortex","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D004594","descriptor_name":"Electrophysiology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D005552","descriptor_name":"Forelimb","qualifier_ui":"Q000294","qualifier_name":"innervation","is_major_topic":false},{"descriptor_ui":"D006614","descriptor_name":"Hindlimb","qualifier_ui":"Q000294","qualifier_name":"innervation","is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008839","descriptor_name":"Microelectrodes","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009473","descriptor_name":"Neuronal Plasticity","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D012785","descriptor_name":"Shoulder Joint","qualifier_ui":"Q000294","qualifier_name":"innervation","is_major_topic":false},{"descriptor_ui":"D013003","descriptor_name":"Somatosensory Cortex","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D013788","descriptor_name":"Thalamus","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D017208","descriptor_name":"Rats, Wistar","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051381","descriptor_name":"Rats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1523/jneurosci.19-19-08623.1999","doi":"https://doi.org/10.1523/jneurosci.19-19-08623.1999","is_oa":true,"landing_page_url":"https://doi.org/10.1523/jneurosci.19-19-08623.1999","pdf_url":"https://www.jneurosci.org/content/jneuro/19/19/8623.full.pdf","source":{"id":"https://openalex.org/S5555990","display_name":"Journal of Neuroscience","issn_l":"0270-6474","issn":["0270-6474","1529-2401"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-b","doyens","jufo-3","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319739","host_organization_name":"Society for Neuroscience","host_organization_lineage":["https://openalex.org/P4310319739"],"host_organization_lineage_names":["Society for Neuroscience"],"type":"journal"},"license":"cc-by-nc-sa","license_id":"https://openalex.org/licenses/cc-by-nc-sa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of Neuroscience","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:6783037","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/6783037","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"J Neurosci","raw_type":"Text"},{"id":"pmid:10493762","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/10493762","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of neuroscience : the official journal of the Society for Neuroscience","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.1523/jneurosci.19-19-08623.1999","doi":"https://doi.org/10.1523/jneurosci.19-19-08623.1999","is_oa":true,"landing_page_url":"https://doi.org/10.1523/jneurosci.19-19-08623.1999","pdf_url":"https://www.jneurosci.org/content/jneuro/19/19/8623.full.pdf","source":{"id":"https://openalex.org/S5555990","display_name":"Journal of Neuroscience","issn_l":"0270-6474","issn":["0270-6474","1529-2401"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-b","doyens","jufo-3","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319739","host_organization_name":"Society for Neuroscience","host_organization_lineage":["https://openalex.org/P4310319739"],"host_organization_lineage_names":["Society for Neuroscience"],"type":"journal"},"license":"cc-by-nc-sa","license_id":"https://openalex.org/licenses/cc-by-nc-sa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of Neuroscience","raw_type":"journal-article"},"sustainable_development_goals":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G3389078549","display_name":"THALAMIC MECHANISMS OF PAIN","funder_award_id":"R01NS036824","funder_id":"https://openalex.org/F4320337359","funder_display_name":"National Institute of Neurological Disorders and Stroke"}],"funders":[{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337359","display_name":"National Institute of Neurological Disorders and Stroke","ror":"https://ror.org/01s5ya894"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2129136659.pdf","grobid_xml":"https://content.openalex.org/works/W2129136659.grobid-xml"},"referenced_works_count":21,"referenced_works":["https://openalex.org/W1748089690","https://openalex.org/W1839128649","https://openalex.org/W1853198620","https://openalex.org/W1969226019","https://openalex.org/W1974162493","https://openalex.org/W1980072648","https://openalex.org/W1993479338","https://openalex.org/W1996737468","https://openalex.org/W2008642640","https://openalex.org/W2009016507","https://openalex.org/W2020776282","https://openalex.org/W2039980517","https://openalex.org/W2048821508","https://openalex.org/W2050423204","https://openalex.org/W2081534285","https://openalex.org/W2086188792","https://openalex.org/W2154292491","https://openalex.org/W2159679428","https://openalex.org/W2163815564","https://openalex.org/W2291310101","https://openalex.org/W2436594805"],"related_works":["https://openalex.org/W2159679428","https://openalex.org/W2275406652","https://openalex.org/W1972764278","https://openalex.org/W2099426569","https://openalex.org/W2161021711","https://openalex.org/W2045655943","https://openalex.org/W1981010162","https://openalex.org/W2094599139","https://openalex.org/W3129410760","https://openalex.org/W2138435074"],"abstract_inverted_index":{"The":[0],"present":[1,172],"study":[2],"examined":[3],"the":[4,7,11,22,41,49,61,80,83,90,99,106,144,151,164],"role":[5],"of":[6,13,24,30,51,63,82,118,146,166],"somatosensory":[8,34,64,126,139],"cortex":[9,35,127,140],"in":[10,89,101,155],"plasticity":[12,18],"thalamic":[14,113,152],"sensory":[15,147],"maps.":[16],"Thalamic":[17],"was":[19,121],"induced":[20],"by":[21,27,116],"disruption":[23],"hindlimb":[25,52,87,119],"input":[26,120],"unilateral":[28],"destruction":[29],"nucleus":[31,107,158],"gracilis.":[32],"Unilateral":[33],"lesions":[36,75,97,128],"were":[37],"performed":[38],"either":[39],"on":[40],"same":[42],"day":[43],"as":[44],"or":[45,86],"a":[46],"week":[47,130],"after":[48],"removal":[50,117],"input.":[53],"Multiple":[54],"electrode":[55],"penetrations":[56],"enabled":[57],"us":[58],"to":[59,67,93,123,157],"measure":[60],"volume":[62,81],"thalamus":[65,91],"devoted":[66],"hindlimb,":[68],"forepaw,":[69,85],"and":[70],"shoulder":[71,102],"body":[72],"regions.":[73],"Cortical":[74],"alone":[76],"did":[77,132],"not":[78,133,162],"change":[79],"shoulder,":[84],"representations":[88],"relative":[92],"controls.":[94],"However,":[95],"these":[96],"blocked":[98],"increase":[100],"representation":[103],"resulting":[104],"from":[105],"gracilis":[108,159],"lesion.":[109],"In":[110],"contrast,":[111],"if":[112],"reorganization":[114,149],"caused":[115],"allowed":[122],"occur,":[124],"subsequent":[125],"1":[129],"later":[131],"prevent":[134],"reorganization.":[135],"Thus,":[136],"an":[137],"intact":[138],"is":[141],"necessary":[142],"for":[143,163],"occurrence":[145],"map":[148],"at":[150],"level":[153],"(induction)":[154],"response":[156],"lesions,":[160],"but":[161],"maintenance":[165],"such":[167],"changes":[168],"once":[169],"they":[170],"are":[171],"(expression).":[173]},"counts_by_year":[{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":1},{"year":2017,"cited_by_count":1},{"year":2016,"cited_by_count":2},{"year":2014,"cited_by_count":1},{"year":2013,"cited_by_count":1},{"year":2012,"cited_by_count":1}],"updated_date":"2026-11-06T12:05:46.655746","created_date":"2016-06-24T00:00:00"}