{"id":"https://openalex.org/W2129102491","doi":null,"title":"Clinical use of oral antihistamines and intranasal corticosteroids in patients with allergic rhinitis.","display_name":"Clinical use of oral antihistamines and intranasal corticosteroids in patients with allergic rhinitis.","publication_year":2011,"publication_date":"2011-01-01","ids":{"openalex":"https://openalex.org/W2129102491","mag":"2129102491","pmid":"https://pubmed.ncbi.nlm.nih.gov/21905499"},"language":"en","primary_location":{"id":"pmid:21905499","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/21905499","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of investigational allergology & clinical immunology","raw_type":"Clinical Trial"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5015059613","display_name":"Ana M. Navarro","orcid":"https://orcid.org/0000-0001-7722-6057","observed_orcids":["https://orcid.org/0000-0001-7722-6057"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"A Navarro","raw_affiliation_strings":["UGC Intercentros Valme-Roc\u00edo Alergologia, Hospital El Tomillar, Sevilla, Spain. anp01se@saludalia.com"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"UGC Intercentros Valme-Roc\u00edo Alergologia, Hospital El Tomillar, Sevilla, Spain. anp01se@saludalia.com","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5102743528","display_name":"Antonio Valero","orcid":"https://orcid.org/0000-0002-5543-0345","observed_orcids":["https://orcid.org/0000-0002-5543-0345"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"A Valero","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":null,"display_name":"M J Rosales","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"M J Rosales","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5083049912","display_name":"Joaquim Mullol","orcid":"https://orcid.org/0000-0003-3463-5007","observed_orcids":["https://orcid.org/0000-0003-3463-5007"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"J Mullol","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":2.0269,"has_fulltext":false,"cited_by_count":33,"citation_normalized_percentile":{"value":0.85221843,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":99},"biblio":{"volume":"21","issue":"5","first_page":"363","last_page":"9"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10877","display_name":"Allergic Rhinitis and Sensitization","score":0.9980000257492065,"subfield":{"id":"https://openalex.org/subfields/2723","display_name":"Immunology and Allergy"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10877","display_name":"Allergic Rhinitis and Sensitization","score":0.9980000257492065,"subfield":{"id":"https://openalex.org/subfields/2723","display_name":"Immunology and Allergy"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10051","display_name":"Asthma and respiratory diseases","score":0.0008999999845400453,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10634","display_name":"Food Allergy and Anaphylaxis Research","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2723","display_name":"Immunology and Allergy"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/allergic-rhinitis","display_name":"allergic rhinitis","score":1.0},{"id":"https://openalex.org/keywords/oral-antihistamines","display_name":"oral antihistamines","score":0.9319999814033508},{"id":"https://openalex.org/keywords/intranasal-corticosteroids","display_name":"intranasal corticosteroids","score":0.9819999933242798},{"id":"https://openalex.org/keywords/second-generation-antihistamines","display_name":"second-generation antihistamines","score":0.9350000023841858},{"id":"https://openalex.org/keywords/combination-therapy","display_name":"combination therapy","score":0.8040000200271606},{"id":"https://openalex.org/keywords/treatment-preferences","display_name":"treatment preferences","score":0.7710000276565552},{"id":"https://openalex.org/keywords/physician-prescribing","display_name":"physician prescribing","score":0.597000002861023},{"id":"https://openalex.org/keywords/patient-satisfaction","display_name":"patient satisfaction","score":0.7609999775886536},{"id":"https://openalex.org/keywords/guideline-adherence","display_name":"guideline adherence","score":0.6650000214576721},{"id":"https://openalex.org/keywords/persistent-allergic-rhinitis","display_name":"persistent allergic rhinitis","score":0.7630000114440918}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9630652666091919},{"id":"https://openalex.org/C14184104","wikidata":"https://www.wikidata.org/wiki/Q1362526","display_name":"Visual analogue scale","level":2,"score":0.6286906003952026},{"id":"https://openalex.org/C85663871","wikidata":"https://www.wikidata.org/wiki/Q6966562","display_name":"Nasal administration","level":2,"score":0.5999283194541931},{"id":"https://openalex.org/C2776042228","wikidata":"https://www.wikidata.org/wiki/Q35869","display_name":"Asthma","level":2,"score":0.5672423839569092},{"id":"https://openalex.org/C2778311950","wikidata":"https://www.wikidata.org/wiki/Q7363","display_name":"Nose","level":2,"score":0.5647683143615723},{"id":"https://openalex.org/C2781413609","wikidata":"https://www.wikidata.org/wiki/Q7308373","display_name":"Regimen","level":2,"score":0.4796079397201538},{"id":"https://openalex.org/C23131810","wikidata":"https://www.wikidata.org/wiki/Q818574","display_name":"Observational study","level":2,"score":0.4712512791156769},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.45991674065589905},{"id":"https://openalex.org/C2779028295","wikidata":"https://www.wikidata.org/wiki/Q8564098","display_name":"Fluticasone propionate","level":3,"score":0.41474443674087524},{"id":"https://openalex.org/C2776989088","wikidata":"https://www.wikidata.org/wiki/Q16364","display_name":"Throat","level":2,"score":0.41039901971817017},{"id":"https://openalex.org/C187212893","wikidata":"https://www.wikidata.org/wiki/Q123028","display_name":"Pediatrics","level":1,"score":0.34666678309440613},{"id":"https://openalex.org/C42219234","wikidata":"https://www.wikidata.org/wiki/Q131130","display_name":"Anesthesia","level":1,"score":0.23510155081748962},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.17762508988380432},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.09232744574546814}],"mesh":[{"descriptor_ui":"D000305","descriptor_name":"Adrenal Cortex Hormones","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000485","descriptor_name":"Allergens","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D006109","descriptor_name":"Poaceae","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006255","descriptor_name":"Rhinitis, Allergic, Seasonal","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":false},{"descriptor_ui":"D006255","descriptor_name":"Rhinitis, Allergic, Seasonal","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":true},{"descriptor_ui":"D006633","descriptor_name":"Histamine Antagonists","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010818","descriptor_name":"Practice Patterns, Physicians'","qualifier_ui":"Q000706","qualifier_name":"statistics & numerical data","is_major_topic":true},{"descriptor_ui":"D011058","descriptor_name":"Pollen","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D011795","descriptor_name":"Surveys and Questionnaires","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013030","descriptor_name":"Spain","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017060","descriptor_name":"Patient Satisfaction","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017410","descriptor_name":"Practice Guidelines as Topic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D055118","descriptor_name":"Medication Adherence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D055656","descriptor_name":"Prescriptions","qualifier_ui":"Q000706","qualifier_name":"statistics & numerical data","is_major_topic":true},{"descriptor_ui":"D057240","descriptor_name":"Patient Preference","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"pmid:21905499","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/21905499","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of investigational allergology & clinical immunology","raw_type":"Clinical Trial"},{"id":"mag:2129102491","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/21905499","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.9907000064849854,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":34,"referenced_works":["https://openalex.org/W1256264546","https://openalex.org/W1510248359","https://openalex.org/W1561512817","https://openalex.org/W1593743641","https://openalex.org/W1766220812","https://openalex.org/W1826685680","https://openalex.org/W1910995839","https://openalex.org/W1971720055","https://openalex.org/W1973974516","https://openalex.org/W1979053557","https://openalex.org/W1994582997","https://openalex.org/W2001450061","https://openalex.org/W2006706598","https://openalex.org/W2024071154","https://openalex.org/W2026994745","https://openalex.org/W2027663129","https://openalex.org/W2032982186","https://openalex.org/W2038939621","https://openalex.org/W2049218836","https://openalex.org/W2059334265","https://openalex.org/W2074817284","https://openalex.org/W2078156738","https://openalex.org/W2084001827","https://openalex.org/W2086041241","https://openalex.org/W2091354422","https://openalex.org/W2101117960","https://openalex.org/W2106503981","https://openalex.org/W2108630923","https://openalex.org/W2111692694","https://openalex.org/W2120372421","https://openalex.org/W2129962151","https://openalex.org/W2129964076","https://openalex.org/W2164132449","https://openalex.org/W2276836119"],"related_works":["https://openalex.org/W2947330490","https://openalex.org/W2443506426","https://openalex.org/W4408410188","https://openalex.org/W2107712135","https://openalex.org/W3107556833","https://openalex.org/W3150511121","https://openalex.org/W3094923497","https://openalex.org/W7128127905","https://openalex.org/W146972808","https://openalex.org/W7213880170"],"abstract_inverted_index":{"BACKGROUND:":[0],"Second-generation":[1],"oral":[2,271],"antihistamines":[3,243],"(AH)":[4],"and":[5,27,56,64,90,108,112,119,134,141,185,213,245,264,273,279],"intranasal":[6,214],"corticosteroids":[7],"(ICS)":[8],"are":[9],"the":[10,24,68,82,131,146,191,204,208,252,257,277],"most":[11],"widely":[12],"used":[13,115],"drugs":[14,31,59,247],"for":[15,26,55,60,165,200,224],"allergic":[16],"rhinitis":[17],"(AR).":[18],"OBJECTIVE:":[19],"To":[20],"obtain":[21],"information":[22,52],"on":[23,53,137],"preferences":[25,54,97],"applications":[28],"of":[29,34,58,77,121,130,150,256,259,276,281],"these":[30],"under":[32],"conditions":[33],"routine":[35],"clinical":[36],"practice.":[37],"METHODS:":[38],"We":[39],"performed":[40],"a":[41,49,127],"multicenter":[42],"multidisciplinary":[43],"observational":[44],"study.":[45],"Participating":[46],"physicians":[47,79],"completed":[48],"questionnaire":[50],"with":[51,67,103,235,270],"application":[57],"AR,":[61,177,180,183,187],"patient":[62],"characteristics,":[63],"physician/patient":[65],"satisfaction":[66],"treatment":[69,211,215,250,269],"provided":[70],"(visual":[71],"analog":[72],"scale).":[73],"RESULTS:":[74],"A":[75,148],"total":[76,149],"1008":[78],"participated":[80],"in":[81,98],"study":[83],"(primary":[84],"care":[85],"physicians,":[86],"53%;":[87],"ear,":[88],"nose,":[89],"throat":[91],"specialists,":[92],"28%;":[93],"allergologists,":[94],"19%).":[95],"Treatment":[96],"AR":[99,166],"were":[100,114,153,167,217,232],"AH":[101,106,111,233,238,272],"combined":[102,234],"ICS":[104,109,113,236,240],"(7.68),":[105],"(7.25),":[107],"(6.94).":[110],"continuously":[116],"by":[117,207],"58%":[118],"71%":[120],"patients,":[122],"respectively.":[123],"Physicians":[124,262],"reported":[125],"having":[126],"good":[128],"knowledge":[129],"Allergic":[132],"Rhinitis":[133],"its":[135],"Impact":[136],"Asthma":[138],"guidelines":[139],"(93%),":[140],"90%":[142],"claimed":[143],"to":[144,193],"follow":[145],"guidelines.":[147],"4040":[151],"patients":[152],"recruited":[154],"(52%":[155],"females,":[156],"mean":[157,170],"[SD]":[158],"age":[159],"34":[160],"[14]":[161],"years).":[162],"The":[163,229],"findings":[164],"as":[168],"follows:":[169],"(SD)":[171],"duration,":[172],"9":[173],"(8)":[174],"years;":[175],"persistent":[176],"52%;":[178],"mild":[179],"72%;":[181],"moderate":[182],"7%;":[184],"severe":[186],"1%.":[188],"Patients":[189],"considered":[190],"disorder":[192],"be":[194],"well":[195],"controlled/almost":[196],"controlled":[197],"(79%).":[198],"As":[199],"treatment,":[201],"77%":[202],"followed":[203],"regimen":[205],"recommended":[206],"physician.":[209],"Oral":[210],"(41%)":[212],"(22%)":[216],"preferred,":[218],"while":[219],"35%":[220],"showed":[221],"no":[222],"preference":[223],"any":[225],"given":[226],"administration":[227],"route.":[228],"treatments":[230],"prescribed":[231],"(66%),":[237],"(20%),":[239],"(11%),":[241],"other":[242,246],"(4%),":[244],"(6%).":[248],"Combination":[249],"was":[251],"preferred":[253],"therapy,":[254],"regardless":[255,275],"type":[258],"rhinitis.":[260],"CONCLUSIONS:":[261],"prefer":[263],"more":[265],"often":[266],"use":[267],"combination":[268],"ICS,":[274],"frequency":[278],"intensity":[280],"AR.":[282]},"counts_by_year":[{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":1},{"year":2020,"cited_by_count":2},{"year":2019,"cited_by_count":3},{"year":2018,"cited_by_count":5},{"year":2017,"cited_by_count":3},{"year":2016,"cited_by_count":1},{"year":2015,"cited_by_count":7},{"year":2014,"cited_by_count":4},{"year":2013,"cited_by_count":3},{"year":2012,"cited_by_count":2}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}