{"id":"https://openalex.org/W2128669068","doi":"https://doi.org/10.1016/j.chom.2010.12.004","title":"Virulence of Mycobacterium tuberculosis Depends on Lipoamide Dehydrogenase, a Member of Three Multienzyme Complexes","display_name":"Virulence of Mycobacterium tuberculosis Depends on Lipoamide Dehydrogenase, a Member of Three Multienzyme Complexes","publication_year":2011,"publication_date":"2011-01-01","ids":{"openalex":"https://openalex.org/W2128669068","doi":"https://doi.org/10.1016/j.chom.2010.12.004","mag":"2128669068","pmid":"https://pubmed.ncbi.nlm.nih.gov/21238944","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/3040420"},"language":"en","primary_location":{"id":"doi:10.1016/j.chom.2010.12.004","doi":"https://doi.org/10.1016/j.chom.2010.12.004","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.chom.2010.12.004","pdf_url":"http://www.cell.com/article/S1931312810004142/pdf","source":{"id":"https://openalex.org/S207313999","display_name":"Cell Host & Microbe","issn_l":"1931-3128","issn":["1931-3128","1934-6069"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315673","host_organization_name":"Cell Press","host_organization_lineage":["https://openalex.org/P4310315673","https://openalex.org/P4310320990"],"host_organization_lineage_names":["Cell Press","Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cell Host &amp; Microbe","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"http://www.cell.com/article/S1931312810004142/pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5110047067","display_name":"Aditya Venugopal","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I205783295","display_name":"Cornell University","ror":"https://ror.org/05bnh6r87","country_code":"US","type":"education","lineage":["https://openalex.org/I205783295"]},{"id":"https://openalex.org/I4387153466","display_name":"Weill Cornell Medicine","ror":"https://ror.org/02r109517","country_code":"US","type":"education","lineage":["https://openalex.org/I205783295","https://openalex.org/I4387153466"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Aditya Venugopal","raw_affiliation_strings":["Department of Microbiology and Immunology, Weill Cornell Medical College, 1300 York Avenue, New York, NY 10065, USA","Program in Immunology and Microbial Pathogenesis, Weill Graduate School of Medical Sciences, Cornell University, 1300 York Avenue, New\u00a0York, NY 10065, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Microbiology and Immunology, Weill Cornell Medical College, 1300 York Avenue, New York, NY 10065, USA","institution_ids":["https://openalex.org/I4387153466"]},{"raw_affiliation_string":"Program in Immunology and Microbial Pathogenesis, Weill Graduate School of Medical Sciences, Cornell University, 1300 York Avenue, New\u00a0York, NY 10065, USA","institution_ids":["https://openalex.org/I205783295","https://openalex.org/I4387153466"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5007492302","display_name":"Ruslana Bryk","orcid":"https://orcid.org/0000-0002-2179-671X","observed_orcids":["https://orcid.org/0000-0002-2179-671X"]},"institutions":[{"id":"https://openalex.org/I4387153466","display_name":"Weill Cornell Medicine","ror":"https://ror.org/02r109517","country_code":"US","type":"education","lineage":["https://openalex.org/I205783295","https://openalex.org/I4387153466"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Ruslana Bryk","raw_affiliation_strings":["Department of Microbiology and Immunology, Weill Cornell Medical College, 1300 York Avenue, New York, NY 10065, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Microbiology and Immunology, Weill Cornell Medical College, 1300 York Avenue, New York, NY 10065, USA","institution_ids":["https://openalex.org/I4387153466"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5035209707","display_name":"Shuangping Shi","orcid":"https://orcid.org/0000-0002-7875-3569","observed_orcids":["https://orcid.org/0000-0002-7875-3569"]},"institutions":[{"id":"https://openalex.org/I205783295","display_name":"Cornell University","ror":"https://ror.org/05bnh6r87","country_code":"US","type":"education","lineage":["https://openalex.org/I205783295"]},{"id":"https://openalex.org/I4387153466","display_name":"Weill Cornell Medicine","ror":"https://ror.org/02r109517","country_code":"US","type":"education","lineage":["https://openalex.org/I205783295","https://openalex.org/I4387153466"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Shuangping Shi","raw_affiliation_strings":["Department of Microbiology and Immunology, Weill Cornell Medical College, 1300 York Avenue, New York, NY 10065, USA","Program in Immunology and Microbial Pathogenesis, Weill Graduate School of Medical Sciences, Cornell University, 1300 York Avenue, New\u00a0York, NY 10065, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Microbiology and Immunology, Weill Cornell Medical College, 1300 York Avenue, New York, NY 10065, USA","institution_ids":["https://openalex.org/I4387153466"]},{"raw_affiliation_string":"Program in Immunology and Microbial Pathogenesis, Weill Graduate School of Medical Sciences, Cornell University, 1300 York Avenue, New\u00a0York, NY 10065, USA","institution_ids":["https://openalex.org/I205783295","https://openalex.org/I4387153466"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5080724294","display_name":"Kyu Young Rhee","orcid":"https://orcid.org/0000-0003-4582-2895","observed_orcids":["https://orcid.org/0000-0003-4582-2895"]},"institutions":[{"id":"https://openalex.org/I4387153466","display_name":"Weill Cornell Medicine","ror":"https://ror.org/02r109517","country_code":"US","type":"education","lineage":["https://openalex.org/I205783295","https://openalex.org/I4387153466"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Kyu Rhee","raw_affiliation_strings":["Division of Infectious Diseases, Department of Medicine, Weill Cornell Medical College, 1300 York Avenue, New York, NY 10065, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Infectious Diseases, Department of Medicine, Weill Cornell Medical College, 1300 York Avenue, New York, NY 10065, USA","institution_ids":["https://openalex.org/I4387153466"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5076940427","display_name":"Poonam Rath","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I205783295","display_name":"Cornell University","ror":"https://ror.org/05bnh6r87","country_code":"US","type":"education","lineage":["https://openalex.org/I205783295"]},{"id":"https://openalex.org/I4387153466","display_name":"Weill Cornell Medicine","ror":"https://ror.org/02r109517","country_code":"US","type":"education","lineage":["https://openalex.org/I205783295","https://openalex.org/I4387153466"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Poonam Rath","raw_affiliation_strings":["Department of Microbiology and Immunology, Weill Cornell Medical College, 1300 York Avenue, New York, NY 10065, USA","Program in Immunology and Microbial Pathogenesis, Weill Graduate School of Medical Sciences, Cornell University, 1300 York Avenue, New\u00a0York, NY 10065, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Microbiology and Immunology, Weill Cornell Medical College, 1300 York Avenue, New York, NY 10065, USA","institution_ids":["https://openalex.org/I4387153466"]},{"raw_affiliation_string":"Program in Immunology and Microbial Pathogenesis, Weill Graduate School of Medical Sciences, Cornell University, 1300 York Avenue, New\u00a0York, NY 10065, USA","institution_ids":["https://openalex.org/I205783295","https://openalex.org/I4387153466"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5034087952","display_name":"Dirk Schnappinger","orcid":"https://orcid.org/0000-0002-4445-7219","observed_orcids":["https://orcid.org/0000-0002-4445-7219"]},"institutions":[{"id":"https://openalex.org/I4387153466","display_name":"Weill Cornell Medicine","ror":"https://ror.org/02r109517","country_code":"US","type":"education","lineage":["https://openalex.org/I205783295","https://openalex.org/I4387153466"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Dirk Schnappinger","raw_affiliation_strings":["Department of Microbiology and Immunology, Weill Cornell Medical College, 1300 York Avenue, New York, NY 10065, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Microbiology and Immunology, Weill Cornell Medical College, 1300 York Avenue, New York, NY 10065, USA","institution_ids":["https://openalex.org/I4387153466"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5023886894","display_name":"Sabine Ehrt","orcid":"https://orcid.org/0000-0002-7951-2310","observed_orcids":["https://orcid.org/0000-0002-7951-2310"]},"institutions":[{"id":"https://openalex.org/I205783295","display_name":"Cornell University","ror":"https://ror.org/05bnh6r87","country_code":"US","type":"education","lineage":["https://openalex.org/I205783295"]},{"id":"https://openalex.org/I4387153466","display_name":"Weill Cornell Medicine","ror":"https://ror.org/02r109517","country_code":"US","type":"education","lineage":["https://openalex.org/I205783295","https://openalex.org/I4387153466"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Sabine Ehrt","raw_affiliation_strings":["Department of Microbiology and Immunology, Weill Cornell Medical College, 1300 York Avenue, New York, NY 10065, USA","Program in Immunology and Microbial Pathogenesis, Weill Graduate School of Medical Sciences, Cornell University, 1300 York Avenue, New\u00a0York, NY 10065, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Microbiology and Immunology, Weill Cornell Medical College, 1300 York Avenue, New York, NY 10065, USA","institution_ids":["https://openalex.org/I4387153466"]},{"raw_affiliation_string":"Program in Immunology and Microbial Pathogenesis, Weill Graduate School of Medical Sciences, Cornell University, 1300 York Avenue, New\u00a0York, NY 10065, USA","institution_ids":["https://openalex.org/I205783295","https://openalex.org/I4387153466"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5000793262","display_name":"Carl Nathan","orcid":"https://orcid.org/0000-0002-7744-8896","observed_orcids":["https://orcid.org/0000-0002-7744-8896"]},"institutions":[{"id":"https://openalex.org/I205783295","display_name":"Cornell University","ror":"https://ror.org/05bnh6r87","country_code":"US","type":"education","lineage":["https://openalex.org/I205783295"]},{"id":"https://openalex.org/I4387153466","display_name":"Weill Cornell Medicine","ror":"https://ror.org/02r109517","country_code":"US","type":"education","lineage":["https://openalex.org/I205783295","https://openalex.org/I4387153466"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Carl Nathan","raw_affiliation_strings":["Department of Microbiology and Immunology, Weill Cornell Medical College, 1300 York Avenue, New York, NY 10065, USA","Program in Immunology and Microbial Pathogenesis, Weill Graduate School of Medical Sciences, Cornell University, 1300 York Avenue, New\u00a0York, NY 10065, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Microbiology and Immunology, Weill Cornell Medical College, 1300 York Avenue, New York, NY 10065, USA","institution_ids":["https://openalex.org/I4387153466"]},{"raw_affiliation_string":"Program in Immunology and Microbial Pathogenesis, Weill Graduate School of Medical Sciences, Cornell University, 1300 York Avenue, New\u00a0York, NY 10065, USA","institution_ids":["https://openalex.org/I205783295","https://openalex.org/I4387153466"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5000793262"],"corresponding_institution_ids":["https://openalex.org/I205783295","https://openalex.org/I4387153466"],"apc_list":{"value":10400,"currency":"USD","value_usd":10400},"apc_paid":null,"fwci":9.2108,"has_fulltext":false,"cited_by_count":138,"citation_normalized_percentile":{"value":0.98732624,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":96,"max":100},"biblio":{"volume":"9","issue":"1","first_page":"21","last_page":"31"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10038","display_name":"Tuberculosis Research and Epidemiology","score":0.9970999956130981,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10038","display_name":"Tuberculosis Research and Epidemiology","score":0.9970999956130981,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12915","display_name":"Biochemical Acid Research Studies","score":0.00139999995008111,"subfield":{"id":"https://openalex.org/subfields/1303","display_name":"Biochemistry"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11381","display_name":"Infectious Diseases and Tuberculosis","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/mycobacterium-tuberculosis","display_name":"Mycobacterium tuberculosis","score":0.9919999837875366},{"id":"https://openalex.org/keywords/dihydrolipoamide-dehydrogenase","display_name":"lipoamide dehydrogenase","score":0.9940000176429749},{"id":"https://openalex.org/keywords/pyruvate-dehydrogenase-complex","display_name":"pyruvate dehydrogenase complex","score":0.9520000219345093},{"id":"https://openalex.org/keywords/branched-chain-alpha-keto-acid-dehydrogenase","display_name":"branched-chain ketoacid dehydrogenase","score":0.9909999966621399},{"id":"https://openalex.org/keywords/virulence","display_name":"virulence","score":0.5040000081062317},{"id":"https://openalex.org/keywords/macrophage-survival","display_name":"macrophage survival","score":0.7379999756813049},{"id":"https://openalex.org/keywords/branched-chain-amino-acid-metabolism","display_name":"branched-chain amino acid metabolism","score":0.9179999828338623},{"id":"https://openalex.org/keywords/multienzyme-complex","display_name":"multienzyme complex","score":0.7409999966621399},{"id":"https://openalex.org/keywords/tuberculosis-drug-targets","display_name":"tuberculosis drug targets","score":0.7459999918937683}],"concepts":[{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.7841498851776123},{"id":"https://openalex.org/C2777975735","wikidata":"https://www.wikidata.org/wiki/Q130971","display_name":"Mycobacterium tuberculosis","level":3,"score":0.6558448076248169},{"id":"https://openalex.org/C88099638","wikidata":"https://www.wikidata.org/wiki/Q412856","display_name":"Pyruvate dehydrogenase complex","level":3,"score":0.622794508934021},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.5928061008453369},{"id":"https://openalex.org/C134651460","wikidata":"https://www.wikidata.org/wiki/Q3100717","display_name":"Reductase","level":3,"score":0.5719524621963501},{"id":"https://openalex.org/C89423630","wikidata":"https://www.wikidata.org/wiki/Q7193","display_name":"Microbiology","level":1,"score":0.5254979729652405},{"id":"https://openalex.org/C2776317432","wikidata":"https://www.wikidata.org/wiki/Q412547","display_name":"Dehydrogenase","level":3,"score":0.5017237663269043},{"id":"https://openalex.org/C181199279","wikidata":"https://www.wikidata.org/wiki/Q8047","display_name":"Enzyme","level":2,"score":0.47196662425994873},{"id":"https://openalex.org/C2779649592","wikidata":"https://www.wikidata.org/wiki/Q2655970","display_name":"Acetyltransferase","level":4,"score":0.4569341540336609},{"id":"https://openalex.org/C2775970874","wikidata":"https://www.wikidata.org/wiki/Q2609152","display_name":"Acyltransferase","level":3,"score":0.448544442653656},{"id":"https://openalex.org/C2780374374","wikidata":"https://www.wikidata.org/wiki/Q194309","display_name":"Mycobacterium","level":3,"score":0.44627976417541504},{"id":"https://openalex.org/C120763696","wikidata":"https://www.wikidata.org/wiki/Q419337","display_name":"Dihydrolipoamide dehydrogenase","level":4,"score":0.42616790533065796},{"id":"https://openalex.org/C119157956","wikidata":"https://www.wikidata.org/wiki/Q796604","display_name":"Acetylation","level":3,"score":0.26265913248062134},{"id":"https://openalex.org/C2781069245","wikidata":"https://www.wikidata.org/wiki/Q12204","display_name":"Tuberculosis","level":2,"score":0.2391514778137207},{"id":"https://openalex.org/C523546767","wikidata":"https://www.wikidata.org/wiki/Q10876","display_name":"Bacteria","level":2,"score":0.23517152667045593},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.1720045804977417},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.10161405801773071},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.0},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000597","descriptor_name":"Amino Acids, Branched-Chain","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004195","descriptor_name":"Disease Models, Animal","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008058","descriptor_name":"Dihydrolipoamide Dehydrogenase","qualifier_ui":"Q000172","qualifier_name":"deficiency","is_major_topic":false},{"descriptor_ui":"D008058","descriptor_name":"Dihydrolipoamide Dehydrogenase","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D008168","descriptor_name":"Lung","qualifier_ui":"Q000382","qualifier_name":"microbiology","is_major_topic":false},{"descriptor_ui":"D008264","descriptor_name":"Macrophages","qualifier_ui":"Q000382","qualifier_name":"microbiology","is_major_topic":false},{"descriptor_ui":"D008810","descriptor_name":"Mice, Inbred C57BL","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009097","descriptor_name":"Multienzyme Complexes","qualifier_ui":"Q000172","qualifier_name":"deficiency","is_major_topic":false},{"descriptor_ui":"D009097","descriptor_name":"Multienzyme Complexes","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D009169","descriptor_name":"Mycobacterium tuberculosis","qualifier_ui":"Q000472","qualifier_name":"pathogenicity","is_major_topic":true},{"descriptor_ui":"D013154","descriptor_name":"Spleen","qualifier_ui":"Q000382","qualifier_name":"microbiology","is_major_topic":false},{"descriptor_ui":"D014376","descriptor_name":"Tuberculosis","qualifier_ui":"Q000382","qualifier_name":"microbiology","is_major_topic":false},{"descriptor_ui":"D014376","descriptor_name":"Tuberculosis","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D014774","descriptor_name":"Virulence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D037521","descriptor_name":"Virulence Factors","qualifier_ui":"Q000172","qualifier_name":"deficiency","is_major_topic":false},{"descriptor_ui":"D037521","descriptor_name":"Virulence Factors","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D058491","descriptor_name":"Bacterial Load","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.1016/j.chom.2010.12.004","doi":"https://doi.org/10.1016/j.chom.2010.12.004","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.chom.2010.12.004","pdf_url":"http://www.cell.com/article/S1931312810004142/pdf","source":{"id":"https://openalex.org/S207313999","display_name":"Cell Host & Microbe","issn_l":"1931-3128","issn":["1931-3128","1934-6069"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315673","host_organization_name":"Cell Press","host_organization_lineage":["https://openalex.org/P4310315673","https://openalex.org/P4310320990"],"host_organization_lineage_names":["Cell Press","Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cell Host &amp; Microbe","raw_type":"journal-article"},{"id":"pmid:21238944","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/21238944","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cell host & microbe","raw_type":"Journal Article"},{"id":"pmh:oai:europepmc.org:2267539","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3040420","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":null,"raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:3040420","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3040420","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"Cell Host Microbe","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1016/j.chom.2010.12.004","doi":"https://doi.org/10.1016/j.chom.2010.12.004","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.chom.2010.12.004","pdf_url":"http://www.cell.com/article/S1931312810004142/pdf","source":{"id":"https://openalex.org/S207313999","display_name":"Cell Host & Microbe","issn_l":"1931-3128","issn":["1931-3128","1934-6069"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315673","host_organization_name":"Cell Press","host_organization_lineage":["https://openalex.org/P4310315673","https://openalex.org/P4310320990"],"host_organization_lineage_names":["Cell Press","Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cell Host &amp; Microbe","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.8371999859809875,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G2728839920","display_name":"Biology of lipoamide dehydrogenase and 2-hydroxy-3-oxoadipate synthase in Mtb","funder_award_id":"R01AI064768","funder_id":"https://openalex.org/F4320337355","funder_display_name":"National Institute of Allergy and Infectious Diseases"},{"id":"https://openalex.org/G7515995078","display_name":"Metabolomics approaches to TB drug development","funder_award_id":"R21AI081094","funder_id":"https://openalex.org/F4320337355","funder_display_name":"National Institute of Allergy and Infectious Diseases"}],"funders":[{"id":"https://openalex.org/F4320306199","display_name":"Hearst Foundations","ror":"https://ror.org/03s96de24"},{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320332513","display_name":"Weill Cornell Medical College","ror":"https://ror.org/02r109517"},{"id":"https://openalex.org/F4320337355","display_name":"National Institute of Allergy and Infectious Diseases","ror":"https://ror.org/043z4tv69"}],"has_content":{"pdf":true,"grobid_xml":false},"content_urls":{"pdf":"https://content.openalex.org/works/W2128669068.pdf"},"referenced_works_count":55,"referenced_works":["https://openalex.org/W1535340464","https://openalex.org/W1549903994","https://openalex.org/W1668019941","https://openalex.org/W1683554639","https://openalex.org/W1963494539","https://openalex.org/W1969623044","https://openalex.org/W1970032996","https://openalex.org/W1970798262","https://openalex.org/W1975045527","https://openalex.org/W1979955102","https://openalex.org/W1988525424","https://openalex.org/W1991233072","https://openalex.org/W1992002248","https://openalex.org/W1998783652","https://openalex.org/W2007097682","https://openalex.org/W2008402427","https://openalex.org/W2016476286","https://openalex.org/W2018209201","https://openalex.org/W2019323814","https://openalex.org/W2032303370","https://openalex.org/W2036965767","https://openalex.org/W2039132204","https://openalex.org/W2043952643","https://openalex.org/W2047597508","https://openalex.org/W2053867514","https://openalex.org/W2055531830","https://openalex.org/W2061418578","https://openalex.org/W2065542724","https://openalex.org/W2066135800","https://openalex.org/W2070771964","https://openalex.org/W2073663438","https://openalex.org/W2086164999","https://openalex.org/W2089322520","https://openalex.org/W2095753590","https://openalex.org/W2098356079","https://openalex.org/W2106048103","https://openalex.org/W2106084243","https://openalex.org/W2120575207","https://openalex.org/W2122802288","https://openalex.org/W2125112523","https://openalex.org/W2126233060","https://openalex.org/W2128918222","https://openalex.org/W2130046741","https://openalex.org/W2134465902","https://openalex.org/W2136913089","https://openalex.org/W2141417334","https://openalex.org/W2145619440","https://openalex.org/W2147379467","https://openalex.org/W2149200346","https://openalex.org/W2152352130","https://openalex.org/W2158803013","https://openalex.org/W2159586303","https://openalex.org/W2163931695","https://openalex.org/W2165539745","https://openalex.org/W2328340377"],"related_works":["https://openalex.org/W1535340464","https://openalex.org/W2106048103","https://openalex.org/W1979955102","https://openalex.org/W2089322520","https://openalex.org/W2039132204","https://openalex.org/W2052402400","https://openalex.org/W4247600035","https://openalex.org/W7128688654","https://openalex.org/W7113312340","https://openalex.org/W3213517282"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":8},{"year":2025,"cited_by_count":9},{"year":2024,"cited_by_count":4},{"year":2023,"cited_by_count":4},{"year":2022,"cited_by_count":13},{"year":2021,"cited_by_count":9},{"year":2020,"cited_by_count":6},{"year":2019,"cited_by_count":3},{"year":2018,"cited_by_count":10},{"year":2017,"cited_by_count":15},{"year":2016,"cited_by_count":3},{"year":2015,"cited_by_count":13},{"year":2014,"cited_by_count":7},{"year":2013,"cited_by_count":20},{"year":2012,"cited_by_count":12}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}
