{"id":"https://openalex.org/W2128546340","doi":"https://doi.org/10.1128/jvi.00569-12","title":"Frequent and Strong Antibody-Mediated Natural Killer Cell Activation in Response to HIV-1 Env in Individuals with Chronic HIV-1 Infection","display_name":"Frequent and Strong Antibody-Mediated Natural Killer Cell Activation in Response to HIV-1 Env in Individuals with Chronic HIV-1 Infection","publication_year":2012,"publication_date":"2012-04-12","ids":{"openalex":"https://openalex.org/W2128546340","doi":"https://doi.org/10.1128/jvi.00569-12","mag":"2128546340","pmid":"https://pubmed.ncbi.nlm.nih.gov/22496218","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/3393568"},"language":"en","primary_location":{"id":"doi:10.1128/jvi.00569-12","doi":"https://doi.org/10.1128/jvi.00569-12","is_oa":false,"landing_page_url":"https://doi.org/10.1128/jvi.00569-12","pdf_url":null,"source":{"id":"https://openalex.org/S96615428","display_name":"Journal of Virology","issn_l":"0022-538X","issn":["0022-538X","1070-6321","1098-5514"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-a","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320263","host_organization_name":"American Society for Microbiology","host_organization_lineage":["https://openalex.org/P4310320263"],"host_organization_lineage_names":["American Society for Microbiology"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Virology","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3393568","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5081656476","display_name":"Christina Thobakgale","orcid":"https://orcid.org/0000-0001-5619-8894","observed_orcids":["https://orcid.org/0000-0001-5619-8894"]},"institutions":[{"id":"https://openalex.org/I2802422659","display_name":"Ragon Institute of MGH, MIT and Harvard","ror":"https://ror.org/053r20n13","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I136199984","https://openalex.org/I2802422659","https://openalex.org/I4210087915","https://openalex.org/I48633490","https://openalex.org/I63966007"]},{"id":"https://openalex.org/I95023434","display_name":"University of KwaZulu-Natal","ror":"https://ror.org/04qzfn040","country_code":"ZA","type":"education","lineage":["https://openalex.org/I95023434"]}],"countries":["US","ZA"],"is_corresponding":false,"raw_author_name":"Christina F. Thobakgale","raw_affiliation_strings":["HIV Pathogenesis Programme, Doris Duke Medical Research Institute, University of KwaZulu-Natal, Durban, South Africa","Ragon Institute of MIT, MGH, and Harvard, Boston, Massachusetts, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"HIV Pathogenesis Programme, Doris Duke Medical Research Institute, University of KwaZulu-Natal, Durban, South Africa","institution_ids":["https://openalex.org/I95023434"]},{"raw_affiliation_string":"Ragon Institute of MIT, MGH, and Harvard, Boston, Massachusetts, USA","institution_ids":["https://openalex.org/I2802422659"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5053585098","display_name":"Lena Fadda","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]},{"id":"https://openalex.org/I2802422659","display_name":"Ragon Institute of MGH, MIT and Harvard","ror":"https://ror.org/053r20n13","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I136199984","https://openalex.org/I2802422659","https://openalex.org/I4210087915","https://openalex.org/I48633490","https://openalex.org/I63966007"]},{"id":"https://openalex.org/I63966007","display_name":"Massachusetts Institute of Technology","ror":"https://ror.org/042nb2s44","country_code":"US","type":"education","lineage":["https://openalex.org/I63966007"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Lena Fadda","raw_affiliation_strings":["Ragon Institute of MIT, MGH, and Harvard, Boston, Massachusetts, USA","bRagon Institute of MIT, MGH, and Harvard, Boston, Massachusetts, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Ragon Institute of MIT, MGH, and Harvard, Boston, Massachusetts, USA","institution_ids":["https://openalex.org/I2802422659"]},{"raw_affiliation_string":"bRagon Institute of MIT, MGH, and Harvard, Boston, Massachusetts, USA","institution_ids":["https://openalex.org/I136199984","https://openalex.org/I2802422659","https://openalex.org/I63966007"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111625587","display_name":"Kimberly Lane","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]},{"id":"https://openalex.org/I2802422659","display_name":"Ragon Institute of MGH, MIT and Harvard","ror":"https://ror.org/053r20n13","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I136199984","https://openalex.org/I2802422659","https://openalex.org/I4210087915","https://openalex.org/I48633490","https://openalex.org/I63966007"]},{"id":"https://openalex.org/I63966007","display_name":"Massachusetts Institute of Technology","ror":"https://ror.org/042nb2s44","country_code":"US","type":"education","lineage":["https://openalex.org/I63966007"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Kimberly Lane","raw_affiliation_strings":["Ragon Institute of MIT, MGH, and Harvard, Boston, Massachusetts, USA","bRagon Institute of MIT, MGH, and Harvard, Boston, Massachusetts, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Ragon Institute of MIT, MGH, and Harvard, Boston, Massachusetts, USA","institution_ids":["https://openalex.org/I2802422659"]},{"raw_affiliation_string":"bRagon Institute of MIT, MGH, and Harvard, Boston, Massachusetts, USA","institution_ids":["https://openalex.org/I136199984","https://openalex.org/I2802422659","https://openalex.org/I63966007"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103569829","display_name":"Ildik\u00f3 T\u00f3th","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]},{"id":"https://openalex.org/I2802422659","display_name":"Ragon Institute of MGH, MIT and Harvard","ror":"https://ror.org/053r20n13","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I136199984","https://openalex.org/I2802422659","https://openalex.org/I4210087915","https://openalex.org/I48633490","https://openalex.org/I63966007"]},{"id":"https://openalex.org/I63966007","display_name":"Massachusetts Institute of Technology","ror":"https://ror.org/042nb2s44","country_code":"US","type":"education","lineage":["https://openalex.org/I63966007"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Ildiko Toth","raw_affiliation_strings":["Ragon Institute of MIT, MGH, and Harvard, Boston, Massachusetts, USA","bRagon Institute of MIT, MGH, and Harvard, Boston, Massachusetts, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Ragon Institute of MIT, MGH, and Harvard, Boston, Massachusetts, USA","institution_ids":["https://openalex.org/I2802422659"]},{"raw_affiliation_string":"bRagon Institute of MIT, MGH, and Harvard, Boston, Massachusetts, USA","institution_ids":["https://openalex.org/I136199984","https://openalex.org/I2802422659","https://openalex.org/I63966007"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5018486460","display_name":"Florencia Pereyra","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]},{"id":"https://openalex.org/I2802422659","display_name":"Ragon Institute of MGH, MIT and Harvard","ror":"https://ror.org/053r20n13","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I136199984","https://openalex.org/I2802422659","https://openalex.org/I4210087915","https://openalex.org/I48633490","https://openalex.org/I63966007"]},{"id":"https://openalex.org/I63966007","display_name":"Massachusetts Institute of Technology","ror":"https://ror.org/042nb2s44","country_code":"US","type":"education","lineage":["https://openalex.org/I63966007"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Florencia Pereyra","raw_affiliation_strings":["Ragon Institute of MIT, MGH, and Harvard, Boston, Massachusetts, USA","bRagon Institute of MIT, MGH, and Harvard, Boston, Massachusetts, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Ragon Institute of MIT, MGH, and Harvard, Boston, Massachusetts, USA","institution_ids":["https://openalex.org/I2802422659"]},{"raw_affiliation_string":"bRagon Institute of MIT, MGH, and Harvard, Boston, Massachusetts, USA","institution_ids":["https://openalex.org/I136199984","https://openalex.org/I2802422659","https://openalex.org/I63966007"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5030983710","display_name":"Suzane B. Bazner","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]},{"id":"https://openalex.org/I2802422659","display_name":"Ragon Institute of MGH, MIT and Harvard","ror":"https://ror.org/053r20n13","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I136199984","https://openalex.org/I2802422659","https://openalex.org/I4210087915","https://openalex.org/I48633490","https://openalex.org/I63966007"]},{"id":"https://openalex.org/I63966007","display_name":"Massachusetts Institute of Technology","ror":"https://ror.org/042nb2s44","country_code":"US","type":"education","lineage":["https://openalex.org/I63966007"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Suzane Bazner","raw_affiliation_strings":["Ragon Institute of MIT, MGH, and Harvard, Boston, Massachusetts, USA","bRagon Institute of MIT, MGH, and Harvard, Boston, Massachusetts, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Ragon Institute of MIT, MGH, and Harvard, Boston, Massachusetts, USA","institution_ids":["https://openalex.org/I2802422659"]},{"raw_affiliation_string":"bRagon Institute of MIT, MGH, and Harvard, Boston, Massachusetts, USA","institution_ids":["https://openalex.org/I136199984","https://openalex.org/I2802422659","https://openalex.org/I63966007"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5040954811","display_name":"Thumbi Ndung\u2019u","orcid":"https://orcid.org/0000-0003-2962-3992","observed_orcids":["https://orcid.org/0000-0003-2962-3992"]},"institutions":[{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]},{"id":"https://openalex.org/I2802422659","display_name":"Ragon Institute of MGH, MIT and Harvard","ror":"https://ror.org/053r20n13","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I136199984","https://openalex.org/I2802422659","https://openalex.org/I4210087915","https://openalex.org/I48633490","https://openalex.org/I63966007"]},{"id":"https://openalex.org/I63966007","display_name":"Massachusetts Institute of Technology","ror":"https://ror.org/042nb2s44","country_code":"US","type":"education","lineage":["https://openalex.org/I63966007"]},{"id":"https://openalex.org/I95023434","display_name":"University of KwaZulu-Natal","ror":"https://ror.org/04qzfn040","country_code":"ZA","type":"education","lineage":["https://openalex.org/I95023434"]}],"countries":["US","ZA"],"is_corresponding":false,"raw_author_name":"Thumbi Ndung'u","raw_affiliation_strings":["HIV Pathogenesis Programme, Doris Duke Medical Research Institute, University of KwaZulu-Natal, Durban, South Africa","Ragon Institute of MIT, MGH, and Harvard, Boston, Massachusetts, USA","aHIV Pathogenesis Programme, Doris Duke Medical Research Institute, University of KwaZulu-Natal, Durban, South Africa","bRagon Institute of MIT, MGH, and Harvard, Boston, Massachusetts, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"HIV Pathogenesis Programme, Doris Duke Medical Research Institute, University of KwaZulu-Natal, Durban, South Africa","institution_ids":["https://openalex.org/I95023434"]},{"raw_affiliation_string":"Ragon Institute of MIT, MGH, and Harvard, Boston, Massachusetts, USA","institution_ids":["https://openalex.org/I2802422659"]},{"raw_affiliation_string":"aHIV Pathogenesis Programme, Doris Duke Medical Research Institute, University of KwaZulu-Natal, Durban, South Africa","institution_ids":["https://openalex.org/I95023434"]},{"raw_affiliation_string":"bRagon Institute of MIT, MGH, and Harvard, Boston, Massachusetts, USA","institution_ids":["https://openalex.org/I136199984","https://openalex.org/I2802422659","https://openalex.org/I63966007"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5016518899","display_name":"Bruce D. Walker","orcid":"https://orcid.org/0000-0001-6122-9245","observed_orcids":["https://orcid.org/0000-0001-6122-9245","https://orcid.org/0000-0002-8506-6740"]},"institutions":[{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]},{"id":"https://openalex.org/I2802422659","display_name":"Ragon Institute of MGH, MIT and Harvard","ror":"https://ror.org/053r20n13","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I136199984","https://openalex.org/I2802422659","https://openalex.org/I4210087915","https://openalex.org/I48633490","https://openalex.org/I63966007"]},{"id":"https://openalex.org/I63966007","display_name":"Massachusetts Institute of Technology","ror":"https://ror.org/042nb2s44","country_code":"US","type":"education","lineage":["https://openalex.org/I63966007"]},{"id":"https://openalex.org/I95023434","display_name":"University of KwaZulu-Natal","ror":"https://ror.org/04qzfn040","country_code":"ZA","type":"education","lineage":["https://openalex.org/I95023434"]}],"countries":["US","ZA"],"is_corresponding":false,"raw_author_name":"Bruce D. Walker","raw_affiliation_strings":["HIV Pathogenesis Programme, Doris Duke Medical Research Institute, University of KwaZulu-Natal, Durban, South Africa","Ragon Institute of MIT, MGH, and Harvard, Boston, Massachusetts, USA","aHIV Pathogenesis Programme, Doris Duke Medical Research Institute, University of KwaZulu-Natal, Durban, South Africa","bRagon Institute of MIT, MGH, and Harvard, Boston, Massachusetts, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"HIV Pathogenesis Programme, Doris Duke Medical Research Institute, University of KwaZulu-Natal, Durban, South Africa","institution_ids":["https://openalex.org/I95023434"]},{"raw_affiliation_string":"Ragon Institute of MIT, MGH, and Harvard, Boston, Massachusetts, USA","institution_ids":["https://openalex.org/I2802422659"]},{"raw_affiliation_string":"aHIV Pathogenesis Programme, Doris Duke Medical Research Institute, University of KwaZulu-Natal, Durban, South Africa","institution_ids":["https://openalex.org/I95023434"]},{"raw_affiliation_string":"bRagon Institute of MIT, MGH, and Harvard, Boston, Massachusetts, USA","institution_ids":["https://openalex.org/I136199984","https://openalex.org/I2802422659","https://openalex.org/I63966007"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5082842988","display_name":"Eric\u00a0S. Rosenberg","orcid":"https://orcid.org/0000-0002-8217-5458","observed_orcids":["https://orcid.org/0000-0002-8217-5458","https://orcid.org/0009-0002-3650-7375"]},"institutions":[{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]},{"id":"https://openalex.org/I2802422659","display_name":"Ragon Institute of MGH, MIT and Harvard","ror":"https://ror.org/053r20n13","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I136199984","https://openalex.org/I2802422659","https://openalex.org/I4210087915","https://openalex.org/I48633490","https://openalex.org/I63966007"]},{"id":"https://openalex.org/I63966007","display_name":"Massachusetts Institute of Technology","ror":"https://ror.org/042nb2s44","country_code":"US","type":"education","lineage":["https://openalex.org/I63966007"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Eric S. Rosenberg","raw_affiliation_strings":["Ragon Institute of MIT, MGH, and Harvard, Boston, Massachusetts, USA","bRagon Institute of MIT, MGH, and Harvard, Boston, Massachusetts, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Ragon Institute of MIT, MGH, and Harvard, Boston, Massachusetts, USA","institution_ids":["https://openalex.org/I2802422659"]},{"raw_affiliation_string":"bRagon Institute of MIT, MGH, and Harvard, Boston, Massachusetts, USA","institution_ids":["https://openalex.org/I136199984","https://openalex.org/I2802422659","https://openalex.org/I63966007"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5059371880","display_name":"Galit Alter","orcid":"https://orcid.org/0000-0002-7680-9215","observed_orcids":["https://orcid.org/0000-0002-7680-9215","https://orcid.org/0000-0002-9221-6735","https://orcid.org/0000-0003-1570-9445"]},"institutions":[{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]},{"id":"https://openalex.org/I2802422659","display_name":"Ragon Institute of MGH, MIT and Harvard","ror":"https://ror.org/053r20n13","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I136199984","https://openalex.org/I2802422659","https://openalex.org/I4210087915","https://openalex.org/I48633490","https://openalex.org/I63966007"]},{"id":"https://openalex.org/I63966007","display_name":"Massachusetts Institute of Technology","ror":"https://ror.org/042nb2s44","country_code":"US","type":"education","lineage":["https://openalex.org/I63966007"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Galit Alter","raw_affiliation_strings":["Ragon Institute of MIT, MGH, and Harvard, Boston, Massachusetts, USA","bRagon Institute of MIT, MGH, and Harvard, Boston, Massachusetts, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Ragon Institute of MIT, MGH, and Harvard, Boston, Massachusetts, USA","institution_ids":["https://openalex.org/I2802422659"]},{"raw_affiliation_string":"bRagon Institute of MIT, MGH, and Harvard, Boston, Massachusetts, USA","institution_ids":["https://openalex.org/I136199984","https://openalex.org/I2802422659","https://openalex.org/I63966007"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5015541994","display_name":"Mary N Carrington","orcid":"https://orcid.org/0000-0002-2692-2180","observed_orcids":["https://orcid.org/0000-0002-2692-2180"]},"institutions":[{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]},{"id":"https://openalex.org/I2802422659","display_name":"Ragon Institute of MGH, MIT and Harvard","ror":"https://ror.org/053r20n13","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I136199984","https://openalex.org/I2802422659","https://openalex.org/I4210087915","https://openalex.org/I48633490","https://openalex.org/I63966007"]},{"id":"https://openalex.org/I4210140884","display_name":"National Cancer Institute","ror":"https://ror.org/040gcmg81","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210140884"]},{"id":"https://openalex.org/I63966007","display_name":"Massachusetts Institute of Technology","ror":"https://ror.org/042nb2s44","country_code":"US","type":"education","lineage":["https://openalex.org/I63966007"]},{"id":"https://openalex.org/I880747138","display_name":"Science Applications International Corporation (United States)","ror":"https://ror.org/00zv91802","country_code":"US","type":"company","lineage":["https://openalex.org/I880747138"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Mary Carrington","raw_affiliation_strings":["Cancer and Inflammation Program, Laboratory of Experimental Immunology, SAIC Frederick, NCI Frederick, Frederick, Maryland, USA","Ragon Institute of MIT, MGH, and Harvard, Boston, Massachusetts, USA","bRagon Institute of MIT, MGH, and Harvard, Boston, Massachusetts, USA","cCancer and Inflammation Program, Laboratory of Experimental Immunology, SAIC Frederick, NCI Frederick, Frederick, Maryland, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Cancer and Inflammation Program, Laboratory of Experimental Immunology, SAIC Frederick, NCI Frederick, Frederick, Maryland, USA","institution_ids":["https://openalex.org/I4210140884","https://openalex.org/I880747138"]},{"raw_affiliation_string":"Ragon Institute of MIT, MGH, and Harvard, Boston, Massachusetts, USA","institution_ids":["https://openalex.org/I2802422659"]},{"raw_affiliation_string":"bRagon Institute of MIT, MGH, and Harvard, Boston, Massachusetts, USA","institution_ids":["https://openalex.org/I136199984","https://openalex.org/I2802422659","https://openalex.org/I63966007"]},{"raw_affiliation_string":"cCancer and Inflammation Program, Laboratory of Experimental Immunology, SAIC Frederick, NCI Frederick, Frederick, Maryland, USA","institution_ids":["https://openalex.org/I4210140884","https://openalex.org/I880747138"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5027975124","display_name":"Todd M. Allen","orcid":"https://orcid.org/0000-0002-6609-1318","observed_orcids":["https://orcid.org/0000-0002-6609-1318"]},"institutions":[{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]},{"id":"https://openalex.org/I2802422659","display_name":"Ragon Institute of MGH, MIT and Harvard","ror":"https://ror.org/053r20n13","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I136199984","https://openalex.org/I2802422659","https://openalex.org/I4210087915","https://openalex.org/I48633490","https://openalex.org/I63966007"]},{"id":"https://openalex.org/I63966007","display_name":"Massachusetts Institute of Technology","ror":"https://ror.org/042nb2s44","country_code":"US","type":"education","lineage":["https://openalex.org/I63966007"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Todd M. Allen","raw_affiliation_strings":["Ragon Institute of MIT, MGH, and Harvard, Boston, Massachusetts, USA","bRagon Institute of MIT, MGH, and Harvard, Boston, Massachusetts, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Ragon Institute of MIT, MGH, and Harvard, Boston, Massachusetts, USA","institution_ids":["https://openalex.org/I2802422659"]},{"raw_affiliation_string":"bRagon Institute of MIT, MGH, and Harvard, Boston, Massachusetts, USA","institution_ids":["https://openalex.org/I136199984","https://openalex.org/I2802422659","https://openalex.org/I63966007"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5042817775","display_name":"Marcus A. Altfeld","orcid":"https://orcid.org/0000-0001-5972-2997","observed_orcids":["https://orcid.org/0000-0001-5972-2997"]},"institutions":[{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]},{"id":"https://openalex.org/I2802422659","display_name":"Ragon Institute of MGH, MIT and Harvard","ror":"https://ror.org/053r20n13","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I136199984","https://openalex.org/I2802422659","https://openalex.org/I4210087915","https://openalex.org/I48633490","https://openalex.org/I63966007"]},{"id":"https://openalex.org/I63966007","display_name":"Massachusetts Institute of Technology","ror":"https://ror.org/042nb2s44","country_code":"US","type":"education","lineage":["https://openalex.org/I63966007"]},{"id":"https://openalex.org/I95023434","display_name":"University of KwaZulu-Natal","ror":"https://ror.org/04qzfn040","country_code":"ZA","type":"education","lineage":["https://openalex.org/I95023434"]}],"countries":["US","ZA"],"is_corresponding":false,"raw_author_name":"Marcus Altfeld","raw_affiliation_strings":["HIV Pathogenesis Programme, Doris Duke Medical Research Institute, University of KwaZulu-Natal, Durban, South Africa","Ragon Institute of MIT, MGH, and Harvard, Boston, Massachusetts, USA","aHIV Pathogenesis Programme, Doris Duke Medical Research Institute, University of KwaZulu-Natal, Durban, South Africa","bRagon Institute of MIT, MGH, and Harvard, Boston, Massachusetts, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"HIV Pathogenesis Programme, Doris Duke Medical Research Institute, University of KwaZulu-Natal, Durban, South Africa","institution_ids":["https://openalex.org/I95023434"]},{"raw_affiliation_string":"Ragon Institute of MIT, MGH, and Harvard, Boston, Massachusetts, USA","institution_ids":["https://openalex.org/I2802422659"]},{"raw_affiliation_string":"aHIV Pathogenesis Programme, Doris Duke Medical Research Institute, University of KwaZulu-Natal, Durban, South Africa","institution_ids":["https://openalex.org/I95023434"]},{"raw_affiliation_string":"bRagon Institute of MIT, MGH, and Harvard, Boston, Massachusetts, USA","institution_ids":["https://openalex.org/I136199984","https://openalex.org/I2802422659","https://openalex.org/I63966007"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":6,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":1.2979,"has_fulltext":false,"cited_by_count":28,"citation_normalized_percentile":{"value":0.77366185,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":98},"biblio":{"volume":"86","issue":"12","first_page":"6986","last_page":"6993"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10112","display_name":"HIV Research and Treatment","score":0.5595999956130981,"subfield":{"id":"https://openalex.org/subfields/2406","display_name":"Virology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10112","display_name":"HIV Research and Treatment","score":0.5595999956130981,"subfield":{"id":"https://openalex.org/subfields/2406","display_name":"Virology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11020","display_name":"Immune Cell Function and Interaction","score":0.43799999356269836,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10082","display_name":"HIV/AIDS Research and Interventions","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/natural-killer-cells","display_name":"natural killer cells","score":0.9750000238418579},{"id":"https://openalex.org/keywords/hiv-1-envelope-glycoprotein","display_name":"HIV-1 envelope glycoprotein","score":0.7649999856948853},{"id":"https://openalex.org/keywords/gp120","display_name":"gp120","score":0.9300000071525574},{"id":"https://openalex.org/keywords/chronic-hiv-1-infection","display_name":"chronic HIV-1 infection","score":0.9419999718666077},{"id":"https://openalex.org/keywords/early-hiv-1-infection","display_name":"early HIV-1 infection","score":0.9580000042915344},{"id":"https://openalex.org/keywords/interferon-gamma","display_name":"interferon-gamma","score":0.7310000061988831},{"id":"https://openalex.org/keywords/tnf-alpha","display_name":"TNF-\u03b1","score":0.9390000104904175},{"id":"https://openalex.org/keywords/cd16","display_name":"CD16","score":0.6579999923706055},{"id":"https://openalex.org/keywords/igg","display_name":"IgG","score":0.5270000100135803}],"concepts":[{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.758880078792572},{"id":"https://openalex.org/C159654299","wikidata":"https://www.wikidata.org/wiki/Q79460","display_name":"Antibody","level":2,"score":0.6486226320266724},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.5889440774917603},{"id":"https://openalex.org/C2781462264","wikidata":"https://www.wikidata.org/wiki/Q78482053","display_name":"CD16","level":5,"score":0.579348087310791},{"id":"https://openalex.org/C129374314","wikidata":"https://www.wikidata.org/wiki/Q909381","display_name":"Interleukin 21","level":4,"score":0.5516475439071655},{"id":"https://openalex.org/C147483822","wikidata":"https://www.wikidata.org/wiki/Q103537","display_name":"Antigen","level":2,"score":0.521252453327179},{"id":"https://openalex.org/C553184892","wikidata":"https://www.wikidata.org/wiki/Q1141429","display_name":"Flow cytometry","level":2,"score":0.5161451101303101},{"id":"https://openalex.org/C8891405","wikidata":"https://www.wikidata.org/wiki/Q1059","display_name":"Immune system","level":2,"score":0.4866095781326294},{"id":"https://openalex.org/C2776178377","wikidata":"https://www.wikidata.org/wiki/Q188269","display_name":"Interferon","level":2,"score":0.48375439643859863},{"id":"https://openalex.org/C206191192","wikidata":"https://www.wikidata.org/wiki/Q17149636","display_name":"NK-92","level":5,"score":0.48082172870635986},{"id":"https://openalex.org/C159047783","wikidata":"https://www.wikidata.org/wiki/Q7215","display_name":"Virology","level":1,"score":0.46670886874198914},{"id":"https://openalex.org/C17991360","wikidata":"https://www.wikidata.org/wiki/Q21173843","display_name":"Tumor necrosis factor alpha","level":2,"score":0.4379897117614746},{"id":"https://openalex.org/C149532602","wikidata":"https://www.wikidata.org/wiki/Q2409681","display_name":"Interleukin 12","level":4,"score":0.4273315966129303},{"id":"https://openalex.org/C2776090121","wikidata":"https://www.wikidata.org/wiki/Q193529","display_name":"T cell","level":3,"score":0.3359822630882263},{"id":"https://openalex.org/C154317977","wikidata":"https://www.wikidata.org/wiki/Q376266","display_name":"Cytotoxic T cell","level":3,"score":0.3306581974029541},{"id":"https://openalex.org/C202751555","wikidata":"https://www.wikidata.org/wiki/Q221681","display_name":"In vitro","level":2,"score":0.10750171542167664},{"id":"https://openalex.org/C114684123","wikidata":"https://www.wikidata.org/wiki/Q419458","display_name":"CD3","level":4,"score":0.0963141918182373},{"id":"https://openalex.org/C167672396","wikidata":"https://www.wikidata.org/wiki/Q417800","display_name":"CD8","level":3,"score":0.0755062997341156},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000914","descriptor_name":"Antibodies, Viral","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D002908","descriptor_name":"Chronic Disease","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007074","descriptor_name":"Immunoglobulin G","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D007371","descriptor_name":"Interferon-gamma","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D007694","descriptor_name":"Killer Cells, Natural","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D008213","descriptor_name":"Lymphocyte Activation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015497","descriptor_name":"HIV-1","qualifier_ui":"Q000145","qualifier_name":"classification","is_major_topic":false},{"descriptor_ui":"D015497","descriptor_name":"HIV-1","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D015497","descriptor_name":"HIV-1","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D015497","descriptor_name":"HIV-1","qualifier_ui":"Q000302","qualifier_name":"isolation & purification","is_major_topic":false},{"descriptor_ui":"D015658","descriptor_name":"HIV Infections","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D015658","descriptor_name":"HIV Infections","qualifier_ui":"Q000821","qualifier_name":"virology","is_major_topic":false},{"descriptor_ui":"D015699","descriptor_name":"HIV Envelope Protein gp120","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true}],"locations_count":5,"locations":[{"id":"doi:10.1128/jvi.00569-12","doi":"https://doi.org/10.1128/jvi.00569-12","is_oa":false,"landing_page_url":"https://doi.org/10.1128/jvi.00569-12","pdf_url":null,"source":{"id":"https://openalex.org/S96615428","display_name":"Journal of Virology","issn_l":"0022-538X","issn":["0022-538X","1070-6321","1098-5514"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-a","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320263","host_organization_name":"American Society for Microbiology","host_organization_lineage":["https://openalex.org/P4310320263"],"host_organization_lineage_names":["American Society for Microbiology"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Virology","raw_type":"journal-article"},{"id":"pmh:oai:europepmc.org:2511434","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3393568","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:3393568","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3393568","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"J Virol","raw_type":"Text"},{"id":"pmid:22496218","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/22496218","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of virology","raw_type":"Journal Article"},{"id":"pmh:oai:CiteSeerX.psu:10.1.1.984.7147","doi":null,"is_oa":false,"landing_page_url":"http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.984.7147","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"http://jvi.asm.org/content/86/12/6986.full.pdf","raw_type":"text"}],"best_oa_location":{"id":"pmh:oai:europepmc.org:2511434","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3393568","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.9537000060081482}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[{"id":"https://openalex.org/G386607036","display_name":null,"funder_award_id":"HHSN261200800001E)","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"},{"id":"https://openalex.org/G4360560478","display_name":"NK cell mediated immune pressure in HIV-1 infection","funder_award_id":"R01AI067031","funder_id":"https://openalex.org/F4320337355","funder_display_name":"National Institute of Allergy and Infectious Diseases"},{"id":"https://openalex.org/G530179354","display_name":"Columbia University-Southern African AIDS International Training/Research Program","funder_award_id":"D43TW000231","funder_id":"https://openalex.org/F4320337356","funder_display_name":"Fogarty International Center"},{"id":"https://openalex.org/G5375337232","display_name":"Acute HIV Infection:  Implications for vaccine design","funder_award_id":"P01AI074415","funder_id":"https://openalex.org/F4320337355","funder_display_name":"National Institute of Allergy and Infectious Diseases"},{"id":"https://openalex.org/G5888954722","display_name":null,"funder_award_id":"HHSN261200800001C","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G8324994064","display_name":null,"funder_award_id":"3 D43 TW000231 16S2","funder_id":"https://openalex.org/F4320337356","funder_display_name":"Fogarty International Center"},{"id":"https://openalex.org/G9000904381","display_name":"Harvard University Center for AIDS Research","funder_award_id":"P30AI060354","funder_id":"https://openalex.org/F4320337355","funder_display_name":"National Institute of Allergy and Infectious Diseases"}],"funders":[{"id":"https://openalex.org/F4320313818","display_name":"Ragon Institute of MGH, MIT and Harvard","ror":"https://ror.org/053r20n13"},{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337351","display_name":"National Cancer Institute","ror":"https://ror.org/040gcmg81"},{"id":"https://openalex.org/F4320337355","display_name":"National Institute of Allergy and Infectious Diseases","ror":"https://ror.org/043z4tv69"},{"id":"https://openalex.org/F4320337356","display_name":"Fogarty International Center","ror":"https://ror.org/02xey9a22"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":32,"referenced_works":["https://openalex.org/W24769773","https://openalex.org/W161539441","https://openalex.org/W1685692620","https://openalex.org/W1966388845","https://openalex.org/W1989712520","https://openalex.org/W1993071851","https://openalex.org/W1998353180","https://openalex.org/W1999782096","https://openalex.org/W2001798824","https://openalex.org/W2003754258","https://openalex.org/W2010449021","https://openalex.org/W2021039830","https://openalex.org/W2021418340","https://openalex.org/W2022069273","https://openalex.org/W2037304054","https://openalex.org/W2039638023","https://openalex.org/W2045551237","https://openalex.org/W2067165659","https://openalex.org/W2084384009","https://openalex.org/W2085091711","https://openalex.org/W2087590625","https://openalex.org/W2089466371","https://openalex.org/W2102227311","https://openalex.org/W2107749930","https://openalex.org/W2115275175","https://openalex.org/W2117971896","https://openalex.org/W2128306333","https://openalex.org/W2142297961","https://openalex.org/W2143814503","https://openalex.org/W2151651155","https://openalex.org/W2152048324","https://openalex.org/W2171709048"],"related_works":["https://openalex.org/W1971586534","https://openalex.org/W2001798824","https://openalex.org/W632724719","https://openalex.org/W2324995608","https://openalex.org/W4236223225","https://openalex.org/W1968475791","https://openalex.org/W2957543848","https://openalex.org/W2527988928","https://openalex.org/W1998353180","https://openalex.org/W2142297961"],"abstract_inverted_index":{"Natural":[0],"killer":[1],"(NK)":[2],"cells":[3,16,32,118,138],"play":[4],"a":[5,59],"critical":[6],"role":[7],"in":[8,45,70,78,171],"the":[9,27,162,191],"control":[10],"of":[11,84,91,125,129,133,164,182,193],"HIV-1":[12,20,34,48,54,73,105,142,200],"infection,":[13],"and":[14,52,62,89,111,127,148,169,203],"NK":[15,31,42,67,101,117,135,137,151,176,183,196],"that":[17],"respond":[18],"to":[19,47,72,104,131,154,158,189],"peptides":[21,49,74,155],"have":[22],"been":[23],"recently":[24],"described.":[25],"However,":[26],"mechanisms":[28],"by":[29],"which":[30],"recognize":[33],"antigens":[35,106],"are":[36,187],"not":[37,76],"fully":[38],"understood.":[39],"We":[40],"investigated":[41],"cell":[43,68,102,152,197],"activation":[44,69,181],"response":[46,71],"during":[50],"early":[51,94],"chronic":[53,87],"clade":[55],"B":[56],"infection":[57,88,95],"using":[58],"whole-blood":[60],"assay":[61],"multiparameter":[63],"flow":[64],"cytometry.":[65],"Antibody-mediated":[66,150],"was":[75],"detected":[77],"HIV-1-uninfected":[79],"individuals.":[80],"In":[81],"contrast,":[82],"79%":[83],"individuals":[85,92],"with":[86,93],"22%":[90],"had":[96],"detectable":[97],"gamma":[98],"interferon":[99],"(IFN-\u03b3)":[100],"responses":[103,153,198],"(P":[107],"<":[108],"0.00001).":[109],"IFN-\u03b3-":[110],"tumor":[112],"necrosis":[113],"factor":[114],"alpha":[115],"(TNF-\u03b1)-producing":[116],"most":[119],"frequently":[120],"targeted":[121,140],"Env":[122,159],"gp120":[123],"(median":[124],"4%":[126],"range":[128],"0":[130],"31%":[132],"all":[134],"cells).":[136],"rarely":[139],"other":[141],"proteins":[143],"such":[144],"as":[145],"Gag,":[146],"Pol,":[147],"Nef.":[149],"mapped":[156],"predominantly":[157],"protein,":[160],"required":[161],"presence":[163],"plasma":[165,167],"or":[166],"IgG,":[168],"resulted":[170],"lower":[172],"CD16":[173],"expression":[174],"on":[175],"cells,":[177],"suggesting":[178],"an":[179],"antibody-mediated":[180,195],"cells.":[184],"Further":[185],"studies":[186],"needed":[188],"assess":[190],"consequences":[192],"these":[194],"for":[199],"disease":[201],"progression":[202],"vaccine-induced":[204],"protection":[205],"from":[206],"infection.":[207]},"counts_by_year":[{"year":2023,"cited_by_count":2},{"year":2022,"cited_by_count":1},{"year":2019,"cited_by_count":3},{"year":2018,"cited_by_count":3},{"year":2017,"cited_by_count":5},{"year":2016,"cited_by_count":4},{"year":2015,"cited_by_count":2},{"year":2014,"cited_by_count":4},{"year":2013,"cited_by_count":2},{"year":2012,"cited_by_count":2}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}
