{"id":"https://openalex.org/W2128416634","doi":"https://doi.org/10.1158/0008-5472.can-05-2237","title":"Red Meat Enhances the Colonic Formation of the DNA Adduct O6-Carboxymethyl Guanine: Implications for Colorectal Cancer Risk","display_name":"Red Meat Enhances the Colonic Formation of the DNA Adduct O6-Carboxymethyl Guanine: Implications for Colorectal Cancer Risk","publication_year":2006,"publication_date":"2006-02-01","ids":{"openalex":"https://openalex.org/W2128416634","doi":"https://doi.org/10.1158/0008-5472.can-05-2237","mag":"2128416634","pmid":"https://pubmed.ncbi.nlm.nih.gov/16452248"},"language":"en","primary_location":{"id":"doi:10.1158/0008-5472.can-05-2237","doi":"https://doi.org/10.1158/0008-5472.can-05-2237","is_oa":true,"landing_page_url":"https://doi.org/10.1158/0008-5472.can-05-2237","pdf_url":"https://aacrjournals.org/cancerres/article-pdf/66/3/1859/2558397/1859.pdf","source":{"id":"https://openalex.org/S168522863","display_name":"Cancer Research","issn_l":"0008-5472","issn":["0008-5472","1538-7445"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320273","host_organization_name":"American Association for Cancer Research","host_organization_lineage":["https://openalex.org/P4310320273"],"host_organization_lineage_names":["American Association for Cancer Research"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cancer Research","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://aacrjournals.org/cancerres/article-pdf/66/3/1859/2558397/1859.pdf","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5066234379","display_name":"Michelle Lewin","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I87048295","display_name":"Wellcome Trust","ror":"https://ror.org/029chgv08","country_code":"GB","type":"nonprofit","lineage":["https://openalex.org/I87048295"]},{"id":"https://openalex.org/I90344618","display_name":"Medical Research Council","ror":"https://ror.org/03x94j517","country_code":"GB","type":"government","lineage":["https://openalex.org/I4210087105","https://openalex.org/I90344618"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Michelle H. Lewin","raw_affiliation_strings":["1Diet and Cancer Group, Dunn Human Nutrition Unit, Wellcome Trust/Medical Research Council Building, Cambridge, United Kingdom;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1Diet and Cancer Group, Dunn Human Nutrition Unit, Wellcome Trust/Medical Research Council Building, Cambridge, United Kingdom;","institution_ids":["https://openalex.org/I87048295","https://openalex.org/I90344618"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5087098250","display_name":"Nina Bailey","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I87048295","display_name":"Wellcome Trust","ror":"https://ror.org/029chgv08","country_code":"GB","type":"nonprofit","lineage":["https://openalex.org/I87048295"]},{"id":"https://openalex.org/I90344618","display_name":"Medical Research Council","ror":"https://ror.org/03x94j517","country_code":"GB","type":"government","lineage":["https://openalex.org/I4210087105","https://openalex.org/I90344618"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Nina Bailey","raw_affiliation_strings":["1Diet and Cancer Group, Dunn Human Nutrition Unit, Wellcome Trust/Medical Research Council Building, Cambridge, United Kingdom;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1Diet and Cancer Group, Dunn Human Nutrition Unit, Wellcome Trust/Medical Research Council Building, Cambridge, United Kingdom;","institution_ids":["https://openalex.org/I87048295","https://openalex.org/I90344618"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109442916","display_name":"Tanya Bandaletova","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I87048295","display_name":"Wellcome Trust","ror":"https://ror.org/029chgv08","country_code":"GB","type":"nonprofit","lineage":["https://openalex.org/I87048295"]},{"id":"https://openalex.org/I90344618","display_name":"Medical Research Council","ror":"https://ror.org/03x94j517","country_code":"GB","type":"government","lineage":["https://openalex.org/I4210087105","https://openalex.org/I90344618"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Tanya Bandaletova","raw_affiliation_strings":["1Diet and Cancer Group, Dunn Human Nutrition Unit, Wellcome Trust/Medical Research Council Building, Cambridge, United Kingdom;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1Diet and Cancer Group, Dunn Human Nutrition Unit, Wellcome Trust/Medical Research Council Building, Cambridge, United Kingdom;","institution_ids":["https://openalex.org/I87048295","https://openalex.org/I90344618"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5036158579","display_name":"Richard Bowman","orcid":"https://orcid.org/0000-0002-6348-2241","observed_orcids":["https://orcid.org/0000-0002-6348-2241"]},"institutions":[{"id":"https://openalex.org/I87048295","display_name":"Wellcome Trust","ror":"https://ror.org/029chgv08","country_code":"GB","type":"nonprofit","lineage":["https://openalex.org/I87048295"]},{"id":"https://openalex.org/I90344618","display_name":"Medical Research Council","ror":"https://ror.org/03x94j517","country_code":"GB","type":"government","lineage":["https://openalex.org/I4210087105","https://openalex.org/I90344618"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Richard Bowman","raw_affiliation_strings":["1Diet and Cancer Group, Dunn Human Nutrition Unit, Wellcome Trust/Medical Research Council Building, Cambridge, United Kingdom;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1Diet and Cancer Group, Dunn Human Nutrition Unit, Wellcome Trust/Medical Research Council Building, Cambridge, United Kingdom;","institution_ids":["https://openalex.org/I87048295","https://openalex.org/I90344618"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5023472770","display_name":"Amanda Jane Cross","orcid":"https://orcid.org/0000-0002-0893-2377","observed_orcids":["https://orcid.org/0000-0002-0893-2377"]},"institutions":[{"id":"https://openalex.org/I87048295","display_name":"Wellcome Trust","ror":"https://ror.org/029chgv08","country_code":"GB","type":"nonprofit","lineage":["https://openalex.org/I87048295"]},{"id":"https://openalex.org/I90344618","display_name":"Medical Research Council","ror":"https://ror.org/03x94j517","country_code":"GB","type":"government","lineage":["https://openalex.org/I4210087105","https://openalex.org/I90344618"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Amanda J. Cross","raw_affiliation_strings":["1Diet and Cancer Group, Dunn Human Nutrition Unit, Wellcome Trust/Medical Research Council Building, Cambridge, United Kingdom;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1Diet and Cancer Group, Dunn Human Nutrition Unit, Wellcome Trust/Medical Research Council Building, Cambridge, United Kingdom;","institution_ids":["https://openalex.org/I87048295","https://openalex.org/I90344618"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5048679801","display_name":"J. R. A. Pollock","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Jim Pollock","raw_affiliation_strings":["2Pollock and Pool Ltd., Reading, Berkshire, United Kingdom; and"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"2Pollock and Pool Ltd., Reading, Berkshire, United Kingdom; and","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5008376652","display_name":"David E. G. Shuker","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I204136569","display_name":"The Open University","ror":"https://ror.org/05mzfcs16","country_code":"GB","type":"education","lineage":["https://openalex.org/I204136569"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"David E.G. Shuker","raw_affiliation_strings":["3Department of Chemistry, The Open University, Walton Hall, Milton Keynes, United Kingdom"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"3Department of Chemistry, The Open University, Walton Hall, Milton Keynes, United Kingdom","institution_ids":["https://openalex.org/I204136569"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5108224557","display_name":"Sheila Anne Bingham","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I87048295","display_name":"Wellcome Trust","ror":"https://ror.org/029chgv08","country_code":"GB","type":"nonprofit","lineage":["https://openalex.org/I87048295"]},{"id":"https://openalex.org/I90344618","display_name":"Medical Research Council","ror":"https://ror.org/03x94j517","country_code":"GB","type":"government","lineage":["https://openalex.org/I4210087105","https://openalex.org/I90344618"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Sheila A. Bingham","raw_affiliation_strings":["1Diet and Cancer Group, Dunn Human Nutrition Unit, Wellcome Trust/Medical Research Council Building, Cambridge, United Kingdom;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1Diet and Cancer Group, Dunn Human Nutrition Unit, Wellcome Trust/Medical Research Council Building, Cambridge, United Kingdom;","institution_ids":["https://openalex.org/I87048295","https://openalex.org/I90344618"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":5.8621,"has_fulltext":true,"cited_by_count":220,"citation_normalized_percentile":{"value":0.97106173,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":95,"max":99},"biblio":{"volume":"66","issue":"3","first_page":"1859","last_page":"1865"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10433","display_name":"Carcinogens and Genotoxicity Assessment","score":0.8637999892234802,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10433","display_name":"Carcinogens and Genotoxicity Assessment","score":0.8637999892234802,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10866","display_name":"Nutritional Studies and Diet","score":0.03579999879002571,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10333","display_name":"Meat and Animal Product Quality","score":0.03350000083446503,"subfield":{"id":"https://openalex.org/subfields/1103","display_name":"Animal Science and Zoology"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/red-meat","display_name":"red meat","score":0.9179999828338623},{"id":"https://openalex.org/keywords/colorectal-cancer-risk","display_name":"colorectal cancer risk","score":0.8190000057220459},{"id":"https://openalex.org/keywords/dna-adducts","display_name":"DNA adducts","score":0.9819999933242798},{"id":"https://openalex.org/keywords/endogenous-nitrosation","display_name":"endogenous nitrosation","score":0.7250000238418579},{"id":"https://openalex.org/keywords/high-fiber-diet","display_name":"high-fiber diet","score":0.7369999885559082},{"id":"https://openalex.org/keywords/vegetarian-diet","display_name":"vegetarian diet","score":0.6790000200271606},{"id":"https://openalex.org/keywords/alkylating-agents","display_name":"alkylating agents","score":0.7739999890327454},{"id":"https://openalex.org/keywords/fecal-biomarkers","display_name":"fecal biomarkers","score":0.4819999933242798}],"concepts":[{"id":"https://openalex.org/C2778089274","wikidata":"https://www.wikidata.org/wiki/Q3243069","display_name":"Red meat","level":2,"score":0.8332529067993164},{"id":"https://openalex.org/C526805850","wikidata":"https://www.wikidata.org/wiki/Q188874","display_name":"Colorectal cancer","level":3,"score":0.6642712950706482},{"id":"https://openalex.org/C61716771","wikidata":"https://www.wikidata.org/wiki/Q496","display_name":"Feces","level":2,"score":0.6194359660148621},{"id":"https://openalex.org/C2778301229","wikidata":"https://www.wikidata.org/wiki/Q169313","display_name":"Guanine","level":4,"score":0.5047110319137573},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.4606352746486664},{"id":"https://openalex.org/C16613235","wikidata":"https://www.wikidata.org/wiki/Q285982","display_name":"Endogeny","level":2,"score":0.45986485481262207},{"id":"https://openalex.org/C2781247443","wikidata":"https://www.wikidata.org/wiki/Q4153410","display_name":"DNA adduct","level":3,"score":0.43471062183380127},{"id":"https://openalex.org/C31903555","wikidata":"https://www.wikidata.org/wiki/Q1637030","display_name":"Food science","level":1,"score":0.42858415842056274},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.42770177125930786},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.38542231917381287},{"id":"https://openalex.org/C140793950","wikidata":"https://www.wikidata.org/wiki/Q168091","display_name":"Animal science","level":1,"score":0.3815726041793823},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.3412612974643707},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.31558746099472046},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.261968195438385},{"id":"https://openalex.org/C552990157","wikidata":"https://www.wikidata.org/wiki/Q7430","display_name":"DNA","level":2,"score":0.24720501899719238},{"id":"https://openalex.org/C512185932","wikidata":"https://www.wikidata.org/wiki/Q28745","display_name":"Nucleotide","level":3,"score":0.23726463317871094},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.12369146943092346},{"id":"https://openalex.org/C151730666","wikidata":"https://www.wikidata.org/wiki/Q7205","display_name":"Paleontology","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002417","descriptor_name":"Cattle","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003106","descriptor_name":"Colon","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D004032","descriptor_name":"Diet","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006147","descriptor_name":"Guanine","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008460","descriptor_name":"Meat","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":true},{"descriptor_ui":"D009603","descriptor_name":"Nitroso Compounds","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D011916","descriptor_name":"Rats, Inbred F344","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012307","descriptor_name":"Risk Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014676","descriptor_name":"Diet, Vegetarian","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015179","descriptor_name":"Colorectal Neoplasms","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":true},{"descriptor_ui":"D015179","descriptor_name":"Colorectal Neoplasms","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D018592","descriptor_name":"Cross-Over Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018736","descriptor_name":"DNA Adducts","qualifier_ui":"Q000096","qualifier_name":"biosynthesis","is_major_topic":true},{"descriptor_ui":"D019073","descriptor_name":"HT29 Cells","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051381","descriptor_name":"Rats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1158/0008-5472.can-05-2237","doi":"https://doi.org/10.1158/0008-5472.can-05-2237","is_oa":true,"landing_page_url":"https://doi.org/10.1158/0008-5472.can-05-2237","pdf_url":"https://aacrjournals.org/cancerres/article-pdf/66/3/1859/2558397/1859.pdf","source":{"id":"https://openalex.org/S168522863","display_name":"Cancer Research","issn_l":"0008-5472","issn":["0008-5472","1538-7445"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320273","host_organization_name":"American Association for Cancer Research","host_organization_lineage":["https://openalex.org/P4310320273"],"host_organization_lineage_names":["American Association for Cancer Research"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cancer Research","raw_type":"journal-article"},{"id":"pmid:16452248","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/16452248","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cancer research","raw_type":"Journal Article"},{"id":"pmh:oai:oro.open.ac.uk:1194","doi":null,"is_oa":false,"landing_page_url":"http://cancerres.aacrjournals.org/cgi/content/abstract/66/3/1859","pdf_url":null,"source":{"id":"https://openalex.org/S4377196284","display_name":"Open Research Online - ORO (The Open University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I204136569","host_organization_name":"The Open University","host_organization_lineage":["https://openalex.org/I204136569"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"PeerReviewed"}],"best_oa_location":{"id":"doi:10.1158/0008-5472.can-05-2237","doi":"https://doi.org/10.1158/0008-5472.can-05-2237","is_oa":true,"landing_page_url":"https://doi.org/10.1158/0008-5472.can-05-2237","pdf_url":"https://aacrjournals.org/cancerres/article-pdf/66/3/1859/2558397/1859.pdf","source":{"id":"https://openalex.org/S168522863","display_name":"Cancer Research","issn_l":"0008-5472","issn":["0008-5472","1538-7445"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320273","host_organization_name":"American Association for Cancer Research","host_organization_lineage":["https://openalex.org/P4310320273"],"host_organization_lineage_names":["American Association for Cancer Research"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cancer Research","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.9476000070571899}],"study_designs":[{"id":"https://openalex.org/study-designs/clinical-trial","display_name":"Clinical Trial"}],"awards":[],"funders":[{"id":"https://openalex.org/F4320334626","display_name":"Medical Research Council","ror":"https://ror.org/03x94j517"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2128416634.pdf","grobid_xml":"https://content.openalex.org/works/W2128416634.grobid-xml"},"referenced_works_count":46,"referenced_works":["https://openalex.org/W1550826397","https://openalex.org/W1677573439","https://openalex.org/W1862016426","https://openalex.org/W1932006408","https://openalex.org/W1974625888","https://openalex.org/W1974789605","https://openalex.org/W1976056213","https://openalex.org/W1996335419","https://openalex.org/W2005970466","https://openalex.org/W2011797056","https://openalex.org/W2015213611","https://openalex.org/W2017188565","https://openalex.org/W2017835062","https://openalex.org/W2018468353","https://openalex.org/W2024817404","https://openalex.org/W2025007845","https://openalex.org/W2037602734","https://openalex.org/W2044896484","https://openalex.org/W2048448304","https://openalex.org/W2056804664","https://openalex.org/W2062148669","https://openalex.org/W2071016823","https://openalex.org/W2094667252","https://openalex.org/W2109191928","https://openalex.org/W2119204879","https://openalex.org/W2121245276","https://openalex.org/W2124318306","https://openalex.org/W2125628175","https://openalex.org/W2126769731","https://openalex.org/W2127321206","https://openalex.org/W2132623481","https://openalex.org/W2137658327","https://openalex.org/W2140533693","https://openalex.org/W2140587505","https://openalex.org/W2141413496","https://openalex.org/W2143949386","https://openalex.org/W2149022033","https://openalex.org/W2149030380","https://openalex.org/W2158579203","https://openalex.org/W2159594827","https://openalex.org/W2167370693","https://openalex.org/W2181773105","https://openalex.org/W2189490860","https://openalex.org/W2417721382","https://openalex.org/W4206645287","https://openalex.org/W4292230194"],"related_works":["https://openalex.org/W2442045946","https://openalex.org/W1974625888","https://openalex.org/W2074552460","https://openalex.org/W2124318306","https://openalex.org/W2792171568","https://openalex.org/W2594113857","https://openalex.org/W1979921579","https://openalex.org/W1970065242","https://openalex.org/W2936784131","https://openalex.org/W1932006408"],"abstract_inverted_index":{"Red":[0],"meat":[1,28,91,133,146,203,243],"is":[2],"associated":[3],"with":[4,88,94,153,182,191,244],"increased":[5],"risk":[6],"of":[7,15,23,86,156,170,241],"colorectal":[8,245],"cancer":[9],"and":[10,40,65,77,186,226,233],"increases":[11],"the":[12,20,89,95,111,116,130,142,154,183,217,239],"endogenous":[13,84],"formation":[14,85],"N-nitrosocompounds":[16],"(NOC).":[17],"To":[18],"investigate":[19],"genotoxic":[21],"effects":[22],"NOC":[24,87,103,199],"arising":[25,200],"from":[26,179,201],"red":[27,37,42,90,132,145,202,242],"consumption,":[29],"human":[30],"volunteers":[31],"were":[32,68,139,150],"fed":[33],"high":[34,41,131,144],"(420":[35],"g)":[36],"meat,":[38,43],"vegetarian,":[39],"high-fiber":[44],"diets":[45],"for":[46,115,160],"15":[47],"days":[48],"in":[49,56,83,105,175,187,216],"a":[50,57,75],"randomized":[51],"crossover":[52],"design":[53],"while":[54],"living":[55],"volunteer":[58],"suite,":[59],"where":[60],"food":[61],"was":[62,74,123,172],"carefully":[63],"controlled":[64],"all":[66],"specimens":[67],"collected.":[69],"In":[70,107,135],"21":[71],"volunteers,":[72,137],"there":[73],"consistent":[76],"significant":[78],"(P":[79,125],"<":[80,126],"0.0001)":[81],"increase":[82],"diet":[92,97],"compared":[93],"vegetarian":[96],"as":[98],"measured":[99],"by":[100],"apparent":[101],"total":[102],"(ATNC)":[104],"feces.":[106],"colonic":[108],"exfoliated":[109],"cells,":[110],"percentage":[112,155],"staining":[113,158],"positive":[114,159],"NOC-specific":[117],"DNA":[118,214],"adduct,":[119],"O(6)-carboxymethyl":[120],"guanine":[121],"(O(6)CMG)":[122],"significantly":[124],"0.001)":[127],"higher":[128],"on":[129,141],"diet.":[134,147],"13":[136],"levels":[138],"intermediate":[140],"high-fiber,":[143],"Fecal":[148],"ATNC":[149],"positively":[151],"correlated":[152],"cells":[157,189],"O(6)CMG":[161,171,221],"(r(2)":[162],"=":[163,166],"0.56,":[164],"P":[165],"0.011).":[167],"The":[168],"presence":[169],"also":[173],"shown":[174,196],"intact":[176],"small":[177],"intestine":[178],"rats":[180],"treated":[181,190],"N-nitrosopeptide":[184],"N-acetyl-N'-prolyl-N'-nitrosoglycine":[185],"HT-29":[188],"diazoacetate.":[192],"This":[193],"study":[194],"has":[195],"that":[197],"fecal":[198],"include":[204],"direct":[205],"acting":[206],"diazopeptides":[207],"or":[208],"N-nitrosopeptides":[209],"able":[210],"to":[211],"form":[212],"alkylating":[213],"adducts":[215,222,230],"colon.":[218],"As":[219],"these":[220],"are":[223,231],"not":[224,234],"repaired,":[225,235],"if":[227],"other":[228],"related":[229],"formed":[232],"this":[236],"may":[237],"explain":[238],"association":[240],"cancer.":[246]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":8},{"year":2024,"cited_by_count":4},{"year":2023,"cited_by_count":10},{"year":2022,"cited_by_count":10},{"year":2021,"cited_by_count":12},{"year":2020,"cited_by_count":12},{"year":2019,"cited_by_count":13},{"year":2018,"cited_by_count":10},{"year":2017,"cited_by_count":11},{"year":2016,"cited_by_count":13},{"year":2015,"cited_by_count":13},{"year":2014,"cited_by_count":12},{"year":2013,"cited_by_count":12},{"year":2012,"cited_by_count":10}],"updated_date":"2026-11-03T10:50:19.383937","created_date":"2016-06-24T00:00:00"}