{"id":"https://openalex.org/W2128406977","doi":"https://doi.org/10.1002/pbc.22452","title":"Hypothyroidism after 131I\u2010monoclonal antibody treatment of neuroblastoma","display_name":"Hypothyroidism after 131I\u2010monoclonal antibody treatment of neuroblastoma","publication_year":2010,"publication_date":"2010-03-08","ids":{"openalex":"https://openalex.org/W2128406977","doi":"https://doi.org/10.1002/pbc.22452","mag":"2128406977","pmid":"https://pubmed.ncbi.nlm.nih.gov/20213847"},"language":"en","primary_location":{"id":"doi:10.1002/pbc.22452","doi":"https://doi.org/10.1002/pbc.22452","is_oa":false,"landing_page_url":"https://doi.org/10.1002/pbc.22452","pdf_url":null,"source":{"id":"https://openalex.org/S119714264","display_name":"Pediatric Blood & Cancer","issn_l":"1545-5009","issn":["1545-5009","1545-5017"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Pediatric Blood & Cancer","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5063829444","display_name":"Sonal Bhandari","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4387153466","display_name":"Weill Cornell Medicine","ror":"https://ror.org/02r109517","country_code":"US","type":"education","lineage":["https://openalex.org/I205783295","https://openalex.org/I4387153466"]},{"id":"https://openalex.org/I4405272987","display_name":"Weill Cornell Medical Center","ror":"https://ror.org/052v90092","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I205783295","https://openalex.org/I4387153466","https://openalex.org/I4405272987"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Sonal Bhandari","raw_affiliation_strings":["Department of Pediatrics, New York Presbyterian-Weill Cornell Medical College, New York, New York, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pediatrics, New York Presbyterian-Weill Cornell Medical College, New York, New York, USA","institution_ids":["https://openalex.org/I4387153466","https://openalex.org/I4405272987"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5034081882","display_name":"Nai\u2010Kong V. Cheung","orcid":"https://orcid.org/0000-0001-6323-5171","observed_orcids":["https://orcid.org/0000-0001-6323-5171"]},"institutions":[{"id":"https://openalex.org/I1334819555","display_name":"Memorial Sloan Kettering Cancer Center","ror":"https://ror.org/02yrq0923","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1334819555"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Nai\u2010Kong V. Cheung","raw_affiliation_strings":["Department of Pediatrics, Memorial Sloan-Kettering Cancer Center, New York, New York"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pediatrics, Memorial Sloan-Kettering Cancer Center, New York, New York","institution_ids":["https://openalex.org/I1334819555"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5043729995","display_name":"Brian H. Kushner","orcid":"https://orcid.org/0000-0002-8916-0697","observed_orcids":["https://orcid.org/0000-0002-8916-0697"]},"institutions":[{"id":"https://openalex.org/I1334819555","display_name":"Memorial Sloan Kettering Cancer Center","ror":"https://ror.org/02yrq0923","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1334819555"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Brian H. Kushner","raw_affiliation_strings":["Department of Pediatrics, Memorial Sloan-Kettering Cancer Center, New York, New York"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pediatrics, Memorial Sloan-Kettering Cancer Center, New York, New York","institution_ids":["https://openalex.org/I1334819555"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5034325765","display_name":"Kim Kramer","orcid":"https://orcid.org/0000-0002-3803-878X","observed_orcids":["https://orcid.org/0000-0002-3803-878X"]},"institutions":[{"id":"https://openalex.org/I1334819555","display_name":"Memorial Sloan Kettering Cancer Center","ror":"https://ror.org/02yrq0923","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1334819555"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Kim Kramer","raw_affiliation_strings":["Department of Pediatrics, Memorial Sloan-Kettering Cancer Center, New York, New York"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pediatrics, Memorial Sloan-Kettering Cancer Center, New York, New York","institution_ids":["https://openalex.org/I1334819555"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5105830310","display_name":"Shakeel I. Modak","orcid":"https://orcid.org/0000-0002-7280-1726","observed_orcids":["https://orcid.org/0000-0002-7280-1726"]},"institutions":[{"id":"https://openalex.org/I1334819555","display_name":"Memorial Sloan Kettering Cancer Center","ror":"https://ror.org/02yrq0923","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1334819555"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Shakeel Modak","raw_affiliation_strings":["Department of Pediatrics, Memorial Sloan-Kettering Cancer Center, New York, New York"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pediatrics, Memorial Sloan-Kettering Cancer Center, New York, New York","institution_ids":["https://openalex.org/I1334819555"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5015396908","display_name":"Steven M. Larson","orcid":"https://orcid.org/0000-0002-6111-7507","observed_orcids":["https://orcid.org/0000-0002-6111-7507"]},"institutions":[{"id":"https://openalex.org/I1334819555","display_name":"Memorial Sloan Kettering Cancer Center","ror":"https://ror.org/02yrq0923","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1334819555"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Steven M. Larson","raw_affiliation_strings":["Department of Nuclear Medicine, Memorial Sloan-Kettering Cancer Center, New York, New York"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Nuclear Medicine, Memorial Sloan-Kettering Cancer Center, New York, New York","institution_ids":["https://openalex.org/I1334819555"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110249936","display_name":"Samuel D. J. Yeh","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1334819555","display_name":"Memorial Sloan Kettering Cancer Center","ror":"https://ror.org/02yrq0923","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1334819555"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Samuel Yeh","raw_affiliation_strings":["Department of Nuclear Medicine, Memorial Sloan-Kettering Cancer Center, New York, New York"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Nuclear Medicine, Memorial Sloan-Kettering Cancer Center, New York, New York","institution_ids":["https://openalex.org/I1334819555"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5031035765","display_name":"Glenn Heller","orcid":"https://orcid.org/0000-0001-9217-8348","observed_orcids":["https://orcid.org/0000-0001-9217-8348"]},"institutions":[{"id":"https://openalex.org/I1334819555","display_name":"Memorial Sloan Kettering Cancer Center","ror":"https://ror.org/02yrq0923","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1334819555"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Glenn Heller","raw_affiliation_strings":["Department of Epidemiology and Biostatistics, Memorial Sloan-Kettering Cancer Center, New York, New York","Department of Epidemiology & Biostatistics Memorial Sloan\u2010Kettering Cancer Center New York New York"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Epidemiology and Biostatistics, Memorial Sloan-Kettering Cancer Center, New York, New York","institution_ids":["https://openalex.org/I1334819555"]},{"raw_affiliation_string":"Department of Epidemiology & Biostatistics Memorial Sloan\u2010Kettering Cancer Center New York New York","institution_ids":["https://openalex.org/I1334819555"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5063077038","display_name":"Charles A. Sklar","orcid":"https://orcid.org/0000-0002-1702-5031","observed_orcids":["https://orcid.org/0000-0002-1702-5031"]},"institutions":[{"id":"https://openalex.org/I1334819555","display_name":"Memorial Sloan Kettering Cancer Center","ror":"https://ror.org/02yrq0923","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1334819555"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Charles A. Sklar","raw_affiliation_strings":["Department of Pediatrics, Memorial Sloan-Kettering Cancer Center, New York, New York"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pediatrics, Memorial Sloan-Kettering Cancer Center, New York, New York","institution_ids":["https://openalex.org/I1334819555"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5063077038"],"corresponding_institution_ids":["https://openalex.org/I1334819555"],"apc_list":{"value":4640,"currency":"USD","value_usd":4640},"apc_paid":null,"fwci":0.3804,"has_fulltext":false,"cited_by_count":7,"citation_normalized_percentile":{"value":0.68479641,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":96},"biblio":{"volume":"55","issue":"1","first_page":"76","last_page":"80"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12226","display_name":"Neuroblastoma Research and Treatments","score":0.5429999828338623,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T12226","display_name":"Neuroblastoma Research and Treatments","score":0.5429999828338623,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11395","display_name":"Radiopharmaceutical Chemistry and Applications","score":0.17759999632835388,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10293","display_name":"Thyroid Disorders and Treatments","score":0.11550000309944153,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/hypothyroidism","display_name":"hypothyroidism","score":0.9359999895095825},{"id":"https://openalex.org/keywords/neuroblastoma","display_name":"neuroblastoma","score":0.8980000019073486},{"id":"https://openalex.org/keywords/monoclonal-antibody-therapy","display_name":"monoclonal antibody therapy","score":0.7739999890327454},{"id":"https://openalex.org/keywords/gd2","display_name":"GD2","score":0.8230000138282776},{"id":"https://openalex.org/keywords/radioimmunotherapy","display_name":"radioimmunotherapy","score":0.7400000095367432},{"id":"https://openalex.org/keywords/thyroid-function","display_name":"thyroid function","score":0.5299999713897705},{"id":"https://openalex.org/keywords/thyroid-protection","display_name":"thyroid protection","score":0.4950000047683716},{"id":"https://openalex.org/keywords/radioiodine-uptake","display_name":"radioiodine uptake","score":0.6520000100135803},{"id":"https://openalex.org/keywords/pediatric-cancer-survivors","display_name":"childhood cancer survivors","score":0.4490000009536743}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8781174421310425},{"id":"https://openalex.org/C2776715637","wikidata":"https://www.wikidata.org/wiki/Q938205","display_name":"Neuroblastoma","level":3,"score":0.7003032565116882},{"id":"https://openalex.org/C526584372","wikidata":"https://www.wikidata.org/wiki/Q16399","display_name":"Thyroid","level":2,"score":0.6463636159896851},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.4965091347694397},{"id":"https://openalex.org/C71315377","wikidata":"https://www.wikidata.org/wiki/Q11364","display_name":"Hormone","level":2,"score":0.48969247937202454},{"id":"https://openalex.org/C2779761222","wikidata":"https://www.wikidata.org/wiki/Q826522","display_name":"Thyroid cancer","level":3,"score":0.4406624734401703},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.4233320653438568},{"id":"https://openalex.org/C90924648","wikidata":"https://www.wikidata.org/wiki/Q120569","display_name":"Gastroenterology","level":1,"score":0.3521230220794678},{"id":"https://openalex.org/C187212893","wikidata":"https://www.wikidata.org/wiki/Q123028","display_name":"Pediatrics","level":1,"score":0.32858771085739136},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0},{"id":"https://openalex.org/C81885089","wikidata":"https://www.wikidata.org/wiki/Q189082","display_name":"Cell culture","level":2,"score":0.0},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D000293","descriptor_name":"Adolescent","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000911","descriptor_name":"Antibodies, Monoclonal","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":false},{"descriptor_ui":"D000911","descriptor_name":"Antibodies, Monoclonal","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D000970","descriptor_name":"Antineoplastic Agents","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":false},{"descriptor_ui":"D000970","descriptor_name":"Antineoplastic Agents","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D002648","descriptor_name":"Child","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002675","descriptor_name":"Child, Preschool","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003131","descriptor_name":"Combined Modality Therapy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007037","descriptor_name":"Hypothyroidism","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":true},{"descriptor_ui":"D007037","descriptor_name":"Hypothyroidism","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":true},{"descriptor_ui":"D007074","descriptor_name":"Immunoglobulin G","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":false},{"descriptor_ui":"D007074","descriptor_name":"Immunoglobulin G","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D007167","descriptor_name":"Immunotherapy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007223","descriptor_name":"Infant","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007457","descriptor_name":"Iodine Radioisotopes","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":false},{"descriptor_ui":"D007457","descriptor_name":"Iodine Radioisotopes","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009447","descriptor_name":"Neuroblastoma","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":false},{"descriptor_ui":"D009447","descriptor_name":"Neuroblastoma","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":true},{"descriptor_ui":"D010524","descriptor_name":"Peripheral Nervous System Neoplasms","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":false},{"descriptor_ui":"D010524","descriptor_name":"Peripheral Nervous System Neoplasms","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":true},{"descriptor_ui":"D015996","descriptor_name":"Survival Rate","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D055815","descriptor_name":"Young Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D058846","descriptor_name":"Antibodies, Monoclonal, Murine-Derived","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1002/pbc.22452","doi":"https://doi.org/10.1002/pbc.22452","is_oa":false,"landing_page_url":"https://doi.org/10.1002/pbc.22452","pdf_url":null,"source":{"id":"https://openalex.org/S119714264","display_name":"Pediatric Blood & Cancer","issn_l":"1545-5009","issn":["1545-5009","1545-5017"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Pediatric Blood & Cancer","raw_type":"journal-article"},{"id":"pmid:20213847","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/20213847","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Pediatric blood & cancer","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":1.0,"id":"https://metadata.un.org/sdg/3"}],"sustainable_development_goals_aurora":[{"display_name":"Good health and well-being","score":0.8299999833106995,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":29,"referenced_works":["https://openalex.org/W1535107443","https://openalex.org/W1960710326","https://openalex.org/W1992027081","https://openalex.org/W1994092038","https://openalex.org/W2020072989","https://openalex.org/W2021235897","https://openalex.org/W2024885019","https://openalex.org/W2025329294","https://openalex.org/W2039990819","https://openalex.org/W2045726657","https://openalex.org/W2059891370","https://openalex.org/W2067606868","https://openalex.org/W2084982062","https://openalex.org/W2094726282","https://openalex.org/W2106739013","https://openalex.org/W2111474003","https://openalex.org/W2124670971","https://openalex.org/W2128282305","https://openalex.org/W2133606662","https://openalex.org/W2139980527","https://openalex.org/W2150708035","https://openalex.org/W2159103399","https://openalex.org/W2164970068","https://openalex.org/W2280578432","https://openalex.org/W2312664798","https://openalex.org/W2327522594","https://openalex.org/W4234934721","https://openalex.org/W4243760006","https://openalex.org/W4254756961"],"related_works":["https://openalex.org/W2045726657","https://openalex.org/W2008536420","https://openalex.org/W4391577667","https://openalex.org/W2124670971","https://openalex.org/W3161797179","https://openalex.org/W7096868879","https://openalex.org/W1557414136","https://openalex.org/W1995125767","https://openalex.org/W2004227347","https://openalex.org/W4306679397"],"abstract_inverted_index":{"BACKGROUND:":[0],"To":[1],"determine":[2],"the":[3,26,56,84,97],"prevalence":[4],"of":[5,96,102,109,126,147,151,169,176],"and":[6,88,149],"risk":[7],"factors":[8],"for":[9,39,94,141,191],"primary":[10,110,170],"hypothyroidism":[11,116,128,152,171],"following":[12,134],"treatment":[13,45,118,135],"with":[14,22,46,55,119,136,179,183],"a":[15,174],"radiolabeled":[16],"monoclonal":[17,51],"antibody":[18,52],"((131)I-3F8)":[19],"in":[20,33,70,173],"children":[21],"neuroblastoma.":[23],"PROCEDURE:":[24],"In":[25],"current":[27],"study,":[28],"we":[29],"assessed":[30],"thyroid":[31,98,192],"function":[32],"51":[34,103],"neuroblastoma":[35],"patients":[36],"who":[37],"survived":[38],">":[40],"or":[41],"=3":[42],"months":[43],"after":[44,117],"(131)I-3F8":[47,120],"(a":[48],"murine":[49],"IgG3":[50],"that":[53,166],"reacts":[54],"ganglioside":[57],"GD2)":[58],"at":[59,131],"4":[60],"mCi/kg/day":[61],"x":[62],"5":[63],"days":[64],"(total":[65],"20":[66],"mCi/kg).":[67],"Prior":[68],"therapy":[69],"all":[71],"subjects":[72,77,104,177],"included":[73],"dose-intensive":[74],"chemotherapy;":[75],"13":[76],"also":[78],"received":[79],"external":[80],"beam":[81],"radiation":[82],"to":[83,115],"neck.":[85],"Oral":[86],"iodide":[87,185],"liothyronine":[89,187],"sodium":[90],"(T3)":[91],"were":[92],"administered":[93],"protection":[95,194],"gland.":[99],"RESULTS:":[100],"Thirty-two":[101],"(63%)":[105],"developed":[106,172],"hormonal":[107,167],"evidence":[108,140,168],"hypothyroidism.":[111],"The":[112,124],"median":[113],"time":[114],"was":[121,129,139],"6.4":[122],"months.":[123],"probability":[125],"developing":[127],"56%":[130],"2":[132],"years":[133],"(131)I-3F8.":[137],"There":[138],"an":[142],"association":[143],"between":[144],"thyroidal":[145],"uptake":[146],"(131)I":[148],"development":[150],"(hazard":[153],"ratio":[154],"1.83,":[155],"95%":[156],"confidence":[157],"interval":[158],"0.91-3.30;":[159],"P":[160],"=":[161],"0.09).":[162],"CONCLUSIONS:":[163],"We":[164],"conclude":[165],"majority":[175],"treated":[178],"(131)I-3F8,":[180],"despite":[181],"pretreatment":[182],"oral":[184],"plus":[186],"sodium.":[188],"Alternative":[189],"strategies":[190],"gland":[193],"are":[195],"needed.":[196]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":1},{"year":2015,"cited_by_count":1},{"year":2013,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}