{"id":"https://openalex.org/W2128288604","doi":"https://doi.org/10.1111/j.1574-6968.2008.01203.x","title":"The alternative sigma factor, \u03c3S, affects polyhydroxyalkanoate metabolism inPseudomonas putida","display_name":"The alternative sigma factor, \u03c3S, affects polyhydroxyalkanoate metabolism inPseudomonas putida","publication_year":2008,"publication_date":"2008-05-21","ids":{"openalex":"https://openalex.org/W2128288604","doi":"https://doi.org/10.1111/j.1574-6968.2008.01203.x","mag":"2128288604","pmid":"https://pubmed.ncbi.nlm.nih.gov/18498401"},"language":"en","primary_location":{"id":"doi:10.1111/j.1574-6968.2008.01203.x","doi":"https://doi.org/10.1111/j.1574-6968.2008.01203.x","is_oa":true,"landing_page_url":"https://doi.org/10.1111/j.1574-6968.2008.01203.x","pdf_url":"https://academic.oup.com/femsle/article-pdf/284/2/218/19608585/284-2-218.pdf","source":{"id":"https://openalex.org/S34954451","display_name":"FEMS Microbiology Letters","issn_l":"0378-1097","issn":["0378-1097","1574-6968"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-3","vabb-shw"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"FEMS Microbiology Letters","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://academic.oup.com/femsle/article-pdf/284/2/218/19608585/284-2-218.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5089421438","display_name":"Laura J. Raiger Iustman","orcid":"https://orcid.org/0000-0002-8541-3204","observed_orcids":["https://orcid.org/0000-0002-8541-3204"]},"institutions":[{"id":"https://openalex.org/I24354313","display_name":"Universidad de Buenos Aires","ror":"https://ror.org/0081fs513","country_code":"AR","type":"education","lineage":["https://openalex.org/I24354313"]}],"countries":["AR"],"is_corresponding":false,"raw_author_name":"Laura J. Raiger-Iustman","raw_affiliation_strings":["Departamento de Qu\u00edmica Biol\u00f3gica, Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires, Buenos Aires, Argentina"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departamento de Qu\u00edmica Biol\u00f3gica, Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires, Buenos Aires, Argentina","institution_ids":["https://openalex.org/I24354313"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5040923328","display_name":"Jimena A. Ruiz","orcid":"https://orcid.org/0000-0003-0908-096X","observed_orcids":["https://orcid.org/0000-0003-0908-096X"]},"institutions":[{"id":"https://openalex.org/I24354313","display_name":"Universidad de Buenos Aires","ror":"https://ror.org/0081fs513","country_code":"AR","type":"education","lineage":["https://openalex.org/I24354313"]}],"countries":["AR"],"is_corresponding":true,"raw_author_name":"Jimena A. Ruiz","raw_affiliation_strings":["Departamento de Qu\u00edmica Biol\u00f3gica, Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires, Buenos Aires, Argentina"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departamento de Qu\u00edmica Biol\u00f3gica, Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires, Buenos Aires, Argentina","institution_ids":["https://openalex.org/I24354313"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5040923328"],"corresponding_institution_ids":["https://openalex.org/I24354313"],"apc_list":{"value":2500,"currency":"GBP","value_usd":3297},"apc_paid":null,"fwci":0.5008,"has_fulltext":true,"cited_by_count":30,"citation_normalized_percentile":{"value":0.58187472,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":98},"biblio":{"volume":"284","issue":"2","first_page":"218","last_page":"224"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10661","display_name":"biodegradable polymer synthesis and properties","score":0.7890999913215637,"subfield":{"id":"https://openalex.org/subfields/2502","display_name":"Biomaterials"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10661","display_name":"biodegradable polymer synthesis and properties","score":0.7890999913215637,"subfield":{"id":"https://openalex.org/subfields/2502","display_name":"Biomaterials"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10120","display_name":"Bacterial Genetics and Biotechnology","score":0.19359999895095825,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10324","display_name":"Microbial bioremediation and biosurfactants","score":0.002199999988079071,"subfield":{"id":"https://openalex.org/subfields/2310","display_name":"Pollution"},"field":{"id":"https://openalex.org/fields/23","display_name":"Environmental Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/stationary-phase","display_name":"stationary phase","score":0.5849999785423279},{"id":"https://openalex.org/keywords/pseudomonas-putida-kt2440","display_name":"Pseudomonas putida KT2440","score":0.9380000233650208},{"id":"https://openalex.org/keywords/phac1","display_name":"phaC1","score":0.9160000085830688},{"id":"https://openalex.org/keywords/rpos-mutant","display_name":"rpoS mutant","score":0.7609999775886536},{"id":"https://openalex.org/keywords/gene-expression-regulation","display_name":"gene expression regulation","score":0.6110000014305115},{"id":"https://openalex.org/keywords/oxidative-stress-tolerance","display_name":"oxidative stress resistance","score":0.8140000104904175},{"id":"https://openalex.org/keywords/stress-survival","display_name":"stress survival","score":0.5910000205039978},{"id":"https://openalex.org/keywords/polyhydroxyalkanoate-accumulation","display_name":"polyhydroxyalkanoate accumulation","score":0.7919999957084656}],"concepts":[{"id":"https://openalex.org/C73447357","wikidata":"https://www.wikidata.org/wiki/Q425079","display_name":"Polyhydroxyalkanoates","level":3,"score":0.984857439994812},{"id":"https://openalex.org/C2777712861","wikidata":"https://www.wikidata.org/wiki/Q7375543","display_name":"rpoS","level":5,"score":0.9029905796051025},{"id":"https://openalex.org/C2780543182","wikidata":"https://www.wikidata.org/wiki/Q2738168","display_name":"Pseudomonas putida","level":3,"score":0.8713350296020508},{"id":"https://openalex.org/C143065580","wikidata":"https://www.wikidata.org/wiki/Q3285695","display_name":"Mutant","level":3,"score":0.5196917653083801},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.479230672121048},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.4213625490665436},{"id":"https://openalex.org/C150194340","wikidata":"https://www.wikidata.org/wiki/Q26972","display_name":"Gene expression","level":3,"score":0.16372910141944885},{"id":"https://openalex.org/C523546767","wikidata":"https://www.wikidata.org/wiki/Q10876","display_name":"Bacteria","level":2,"score":0.15913203358650208},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.15611106157302856},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.1109628975391388},{"id":"https://openalex.org/C101762097","wikidata":"https://www.wikidata.org/wiki/Q224093","display_name":"Promoter","level":4,"score":0.06605631113052368}],"mesh":[{"descriptor_ui":"D001426","descriptor_name":"Bacterial Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D003001","descriptor_name":"Cloning, Molecular","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006861","descriptor_name":"Hydrogen Peroxide","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D010957","descriptor_name":"Plasmids","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011401","descriptor_name":"Promoter Regions, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011993","descriptor_name":"Recombinant Fusion Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D012808","descriptor_name":"Sigma Factor","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D013995","descriptor_name":"Time","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015964","descriptor_name":"Gene Expression Regulation, Bacterial","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016958","descriptor_name":"Pseudomonas putida","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D016958","descriptor_name":"Pseudomonas putida","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D018384","descriptor_name":"Oxidative Stress","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020868","descriptor_name":"Gene Silencing","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D050296","descriptor_name":"Microbial Viability","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D054813","descriptor_name":"Polyhydroxyalkanoates","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true}],"locations_count":6,"locations":[{"id":"doi:10.1111/j.1574-6968.2008.01203.x","doi":"https://doi.org/10.1111/j.1574-6968.2008.01203.x","is_oa":true,"landing_page_url":"https://doi.org/10.1111/j.1574-6968.2008.01203.x","pdf_url":"https://academic.oup.com/femsle/article-pdf/284/2/218/19608585/284-2-218.pdf","source":{"id":"https://openalex.org/S34954451","display_name":"FEMS Microbiology Letters","issn_l":"0378-1097","issn":["0378-1097","1574-6968"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-3","vabb-shw"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"FEMS Microbiology Letters","raw_type":"journal-article"},{"id":"pmid:18498401","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/18498401","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"FEMS microbiology letters","raw_type":"Journal Article"},{"id":"pmh:oai:RDI UBA:artiaex:paper_03781097_v284_n2_p218_RaigerIustman_oai","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/20.500.12110/paper_03781097_v284_n2_p218_RaigerIustman","pdf_url":null,"source":{"id":"https://openalex.org/S4306402562","display_name":"Repositorio Digital Institucional de la Universidad de Buenos Aires (Universidad de Buenos Aires)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I24354313","host_organization_name":"Universidad de Buenos Aires","host_organization_lineage":["https://openalex.org/I24354313"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"FEMS Microbiol. Lett. 2008;284(2):218-224","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:ri.conicet.gov.ar:11336/60880","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/11336/60880","pdf_url":null,"source":{"id":"https://openalex.org/S4306402641","display_name":"LA Referencia (Red Federada de Repositorios Institucionales de Publicaciones Cient\u00edficas)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4383465926","host_organization_name":"LA Referencia","host_organization_lineage":["https://openalex.org/I4383465926"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"reponame:CONICET Digital (CONICET)","raw_type":"http://purl.org/coar/resource_type/c_6501"},{"id":"pmh:paperaa:paper_03781097_v284_n2_p218_RaigerIustman","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/20.500.12110/paper_03781097_v284_n2_p218_RaigerIustman","pdf_url":null,"source":{"id":"https://openalex.org/S4306402641","display_name":"LA Referencia (Red Federada de Repositorios Institucionales de Publicaciones Cient\u00edficas)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4383465926","host_organization_name":"LA Referencia","host_organization_lineage":["https://openalex.org/I4383465926"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"FEMS Microbiol. Lett. 2008;284(2):218-224","raw_type":"http://purl.org/coar/resource_type/c_6501"},{"id":"pmh:oai:americanae.aecid.es:3080119","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/11336/60880","pdf_url":null,"source":{"id":"https://openalex.org/S4306400786","display_name":"Americanae (AECID Library)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-sa","license_id":"https://openalex.org/licenses/cc-by-nc-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"reponame:CONICET Digital (CONICET)","raw_type":"http://purl.org/coar/resource_type/c_6501"}],"best_oa_location":{"id":"doi:10.1111/j.1574-6968.2008.01203.x","doi":"https://doi.org/10.1111/j.1574-6968.2008.01203.x","is_oa":true,"landing_page_url":"https://doi.org/10.1111/j.1574-6968.2008.01203.x","pdf_url":"https://academic.oup.com/femsle/article-pdf/284/2/218/19608585/284-2-218.pdf","source":{"id":"https://openalex.org/S34954451","display_name":"FEMS Microbiology Letters","issn_l":"0378-1097","issn":["0378-1097","1574-6968"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-3","vabb-shw"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"FEMS Microbiology Letters","raw_type":"journal-article"},"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320321594","display_name":"Consejo Nacional de Investigaciones Cient\u00edficas y T\u00e9cnicas","ror":"https://ror.org/03cqe8w59"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2128288604.pdf","grobid_xml":"https://content.openalex.org/works/W2128288604.grobid-xml"},"referenced_works_count":29,"referenced_works":["https://openalex.org/W30618968","https://openalex.org/W1546783991","https://openalex.org/W1548309673","https://openalex.org/W1602573976","https://openalex.org/W1727714182","https://openalex.org/W1940880266","https://openalex.org/W1964245273","https://openalex.org/W1995976964","https://openalex.org/W1999312158","https://openalex.org/W2001658309","https://openalex.org/W2004319015","https://openalex.org/W2023767700","https://openalex.org/W2054920102","https://openalex.org/W2055214700","https://openalex.org/W2063496293","https://openalex.org/W2065864994","https://openalex.org/W2070456988","https://openalex.org/W2079178430","https://openalex.org/W2101530434","https://openalex.org/W2112426955","https://openalex.org/W2139649103","https://openalex.org/W2141247327","https://openalex.org/W2144634347","https://openalex.org/W2152542286","https://openalex.org/W2153189349","https://openalex.org/W2171535756","https://openalex.org/W2172287360","https://openalex.org/W2314225431","https://openalex.org/W2407495465"],"related_works":["https://openalex.org/W2065864994","https://openalex.org/W1982100322","https://openalex.org/W2039661964","https://openalex.org/W2022767265","https://openalex.org/W6902324533","https://openalex.org/W2129182290","https://openalex.org/W2085340322","https://openalex.org/W2740206100","https://openalex.org/W1982303111","https://openalex.org/W2095982787"],"abstract_inverted_index":{"To":[0],"determine":[1],"whether":[2],"the":[3,31,35,51,53,66,70,81,108,112,118,131,136,140],"stationary":[4,71,137],"sigma":[5],"factor,":[6],"sigma(S),":[7],"influences":[8],"polyhydroxyalkanoate":[9,22,40,45,59,85,110,124],"metabolism":[10],"in":[11,84,88,139],"Pseudomonas":[12],"putida":[13],"KT2440,":[14],"an":[15,89],"rpoS-negative":[16],"mutant":[17,55],"was":[18],"constructed":[19],"to":[20,30,122,129],"evaluate":[21],"accumulation":[23,125],"and":[24,44,62,95,102,114],"expression":[25,64],"of":[26,34,65,117],"a":[27,57],"translational":[28,67],"fusion":[29,68],"promoter":[32],"region":[33],"genes":[36,82],"that":[37,77,107,142],"code":[38],"for":[39],"synthase":[41],"1":[42],"(phaC1)":[43],"depolymerase":[46],"(phaZ).":[47],"By":[48],"comparison":[49],"with":[50],"wild-type,":[52],"rpoS":[54,119],"showed":[56],"higher":[58],"degradation":[60],"rate":[61],"increased":[63,111],"during":[69,135],"growth":[72],"phase.":[73],"These":[74],"results":[75],"suggest":[76],"sigma(S)":[78],"might":[79],"control":[80],"involved":[83],"metabolism,":[86],"possibly":[87],"indirect":[90],"manner.":[91],"In":[92],"addition,":[93],"survival":[94,113],"oxidative":[96],"stress":[97,115],"assays":[98],"performed":[99],"under":[100],"polyhydroxyalkanoate-":[101],"nonpolyhydroxyalkanoate-":[103],"accumulating":[104],"conditions":[105,133],"demonstrated":[106],"accumulated":[109],"tolerance":[116],"mutant.":[120],"According":[121],"this,":[123],"would":[126],"help":[127],"cells":[128],"overcome":[130],"adverse":[132],"encountered":[134],"phase":[138],"strain":[141],"lacks":[143],"RpoS.":[144]},"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":1},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":6},{"year":2020,"cited_by_count":2},{"year":2019,"cited_by_count":1},{"year":2018,"cited_by_count":4},{"year":2017,"cited_by_count":2},{"year":2016,"cited_by_count":2},{"year":2015,"cited_by_count":2},{"year":2014,"cited_by_count":1},{"year":2013,"cited_by_count":2},{"year":2012,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}