{"id":"https://openalex.org/W2128200133","doi":"https://doi.org/10.1093/eurheartj/ehq204","title":"Early routine percutaneous coronary intervention after fibrinolysis vs. standard therapy in ST-segment elevation myocardial infarction: a meta-analysis","display_name":"Early routine percutaneous coronary intervention after fibrinolysis vs. standard therapy in ST-segment elevation myocardial infarction: a meta-analysis","publication_year":2010,"publication_date":"2010-07-02","ids":{"openalex":"https://openalex.org/W2128200133","doi":"https://doi.org/10.1093/eurheartj/ehq204","mag":"2128200133","pmid":"https://pubmed.ncbi.nlm.nih.gov/20601393"},"language":"en","primary_location":{"id":"doi:10.1093/eurheartj/ehq204","doi":"https://doi.org/10.1093/eurheartj/ehq204","is_oa":false,"landing_page_url":"https://doi.org/10.1093/eurheartj/ehq204","pdf_url":null,"source":{"id":"https://openalex.org/S181568219","display_name":"European Heart Journal","issn_l":"0195-668X","issn":["0195-668X","1522-9645"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"European Heart Journal","raw_type":"journal-article"},"volume":null,"type":"review","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5023352380","display_name":"Francesco Borgia","orcid":"https://orcid.org/0000-0001-5645-3218","observed_orcids":["https://orcid.org/0000-0001-5645-3218"]},"institutions":[{"id":"https://openalex.org/I4210096640","display_name":"Royal Brompton Hospital","ror":"https://ror.org/00cv4n034","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I2800036501","https://openalex.org/I4210096640"]},{"id":"https://openalex.org/I47508984","display_name":"Imperial College London","ror":"https://ror.org/041kmwe10","country_code":"GB","type":"education","lineage":["https://openalex.org/I47508984"]},{"id":"https://openalex.org/I71267560","display_name":"University of Naples Federico II","ror":"https://ror.org/05290cv24","country_code":"IT","type":"education","lineage":["https://openalex.org/I71267560"]}],"countries":["GB","IT"],"is_corresponding":false,"raw_author_name":"Francesco Borgia","raw_affiliation_strings":["Royal Brompton Hospital and Imperial College, London, UK","Federico II University, Naples, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Royal Brompton Hospital and Imperial College, London, UK","institution_ids":["https://openalex.org/I4210096640","https://openalex.org/I47508984"]},{"raw_affiliation_string":"Federico II University, Naples, Italy","institution_ids":["https://openalex.org/I71267560"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5047187243","display_name":"Shaun G. Goodman","orcid":"https://orcid.org/0000-0001-8068-2440","observed_orcids":["https://orcid.org/0000-0001-8068-2440"]},"institutions":[{"id":"https://openalex.org/I1297363086","display_name":"St. Michael's Hospital","ror":"https://ror.org/04skqfp25","country_code":"CA","type":"healthcare","lineage":["https://openalex.org/I1297363086","https://openalex.org/I4399598460"]},{"id":"https://openalex.org/I185261750","display_name":"University of Toronto","ror":"https://ror.org/03dbr7087","country_code":"CA","type":"education","lineage":["https://openalex.org/I185261750"]},{"id":"https://openalex.org/I4210149657","display_name":"Canadian Heart Research Centre","ror":"https://ror.org/04nv6s061","country_code":"CA","type":"nonprofit","lineage":["https://openalex.org/I4210149657"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Shaun G. Goodman","raw_affiliation_strings":["Canadian Heart Research Centre and St. Michael's Hospital, University of Toronto, Toronto, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Canadian Heart Research Centre and St. Michael's Hospital, University of Toronto, Toronto, Canada","institution_ids":["https://openalex.org/I1297363086","https://openalex.org/I185261750","https://openalex.org/I4210149657"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5057062433","display_name":"Sigrun Halvorsen","orcid":"https://orcid.org/0000-0001-7561-7644","observed_orcids":["https://orcid.org/0000-0001-7561-7644"]},"institutions":[{"id":"https://openalex.org/I1281400175","display_name":"Oslo University Hospital","ror":"https://ror.org/00j9c2840","country_code":"NO","type":"healthcare","lineage":["https://openalex.org/I1281400175"]}],"countries":["NO"],"is_corresponding":false,"raw_author_name":"Sigrun Halvorsen","raw_affiliation_strings":["Oslo University Hospital, Ulleval, Oslo, Norway"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Oslo University Hospital, Ulleval, Oslo, Norway","institution_ids":["https://openalex.org/I1281400175"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5024193392","display_name":"Warren J. Cantor","orcid":"https://orcid.org/0000-0002-7715-6746","observed_orcids":["https://orcid.org/0000-0002-7715-6746"]},"institutions":[{"id":"https://openalex.org/I2802289008","display_name":"Southlake Regional Health Center","ror":"https://ror.org/05ayf4d73","country_code":"CA","type":"healthcare","lineage":["https://openalex.org/I2802289008"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Warren J. Cantor","raw_affiliation_strings":["Southlake Regional Health Centre, Newmarket, ON, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Southlake Regional Health Centre, Newmarket, ON, Canada","institution_ids":["https://openalex.org/I2802289008"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5003180371","display_name":"Federico Piscione","orcid":"https://orcid.org/0000-0003-4911-5135","observed_orcids":["https://orcid.org/0000-0003-4911-5135"]},"institutions":[{"id":"https://openalex.org/I71267560","display_name":"University of Naples Federico II","ror":"https://ror.org/05290cv24","country_code":"IT","type":"education","lineage":["https://openalex.org/I71267560"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Federico Piscione","raw_affiliation_strings":["Federico II University, Naples, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Federico II University, Naples, Italy","institution_ids":["https://openalex.org/I71267560"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5039692883","display_name":"Michel R. Le May","orcid":"https://orcid.org/0000-0002-4643-1709","observed_orcids":["https://orcid.org/0000-0002-4643-1709"]},"institutions":[{"id":"https://openalex.org/I153718931","display_name":"University of Ottawa","ror":"https://ror.org/03c4mmv16","country_code":"CA","type":"education","lineage":["https://openalex.org/I153718931"]},{"id":"https://openalex.org/I4401200298","display_name":"Ottawa Heart Institute","ror":"https://ror.org/00h533452","country_code":"CA","type":"facility","lineage":["https://openalex.org/I153718931","https://openalex.org/I4401200298"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Michel R. Le May","raw_affiliation_strings":["Heart Institute, Univeristy of Ottawa, Ottawa, ON, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Heart Institute, Univeristy of Ottawa, Ottawa, ON, Canada","institution_ids":["https://openalex.org/I153718931","https://openalex.org/I4401200298"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5045484822","display_name":"Francisco Fern\u00e1ndez\u2010Avil\u00e9s","orcid":"https://orcid.org/0000-0001-5501-5275","observed_orcids":["https://orcid.org/0000-0001-5501-5275"]},"institutions":[{"id":"https://openalex.org/I2960094004","display_name":"Hospital General Universitario Gregorio Mara\u00f1\u00f3n","ror":"https://ror.org/0111es613","country_code":"ES","type":"healthcare","lineage":["https://openalex.org/I2960094004","https://openalex.org/I4210139293"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"Francisco Fern\u00e1ndez-Avil\u00e9s","raw_affiliation_strings":["Hospital General Universitario Gregorio Mara\u00f1\u00f3n, Madrid, Spain"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Hospital General Universitario Gregorio Mara\u00f1\u00f3n, Madrid, Spain","institution_ids":["https://openalex.org/I2960094004"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5017420618","display_name":"Pedro Luis Sanchez","orcid":"https://orcid.org/0000-0002-1402-0526","observed_orcids":["https://orcid.org/0000-0002-1402-0526"]},"institutions":[{"id":"https://openalex.org/I2960094004","display_name":"Hospital General Universitario Gregorio Mara\u00f1\u00f3n","ror":"https://ror.org/0111es613","country_code":"ES","type":"healthcare","lineage":["https://openalex.org/I2960094004","https://openalex.org/I4210139293"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"Pedro L. S\u00e1nchez","raw_affiliation_strings":["Hospital General Universitario Gregorio Mara\u00f1\u00f3n, Madrid, Spain"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Hospital General Universitario Gregorio Mara\u00f1\u00f3n, Madrid, Spain","institution_ids":["https://openalex.org/I2960094004"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5007799685","display_name":"Konstantinos Dimopoulos","orcid":"https://orcid.org/0000-0003-1300-0504","observed_orcids":["https://orcid.org/0000-0003-1300-0504"]},"institutions":[{"id":"https://openalex.org/I4210096640","display_name":"Royal Brompton Hospital","ror":"https://ror.org/00cv4n034","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I2800036501","https://openalex.org/I4210096640"]},{"id":"https://openalex.org/I47508984","display_name":"Imperial College London","ror":"https://ror.org/041kmwe10","country_code":"GB","type":"education","lineage":["https://openalex.org/I47508984"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Konstantinos Dimopoulos","raw_affiliation_strings":["Royal Brompton Hospital and Imperial College, London, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Royal Brompton Hospital and Imperial College, London, UK","institution_ids":["https://openalex.org/I4210096640","https://openalex.org/I47508984"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5074717796","display_name":"Bruno Scheller","orcid":"https://orcid.org/0000-0001-7139-5298","observed_orcids":["https://orcid.org/0000-0001-7139-5298"]},"institutions":[{"id":"https://openalex.org/I4210094678","display_name":"Universit\u00e4tsklinikum des Saarlandes","ror":"https://ror.org/00nvxt968","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I4210094678"]},{"id":"https://openalex.org/I91712215","display_name":"Saarland University","ror":"https://ror.org/01jdpyv68","country_code":"DE","type":"education","lineage":["https://openalex.org/I91712215"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Bruno Scheller","raw_affiliation_strings":["Innere Medizin III, Universitat des Saarlandes, Homburg, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Innere Medizin III, Universitat des Saarlandes, Homburg, Germany","institution_ids":["https://openalex.org/I4210094678","https://openalex.org/I91712215"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5023634772","display_name":"Paul W. Armstrong","orcid":"https://orcid.org/0000-0002-0460-3445","observed_orcids":["https://orcid.org/0000-0002-0460-3445","https://orcid.org/0000-0001-7553-1090"]},"institutions":[{"id":"https://openalex.org/I154425047","display_name":"University of Alberta","ror":"https://ror.org/0160cpw27","country_code":"CA","type":"education","lineage":["https://openalex.org/I154425047"]},{"id":"https://openalex.org/I4210111431","display_name":"Canadian VIGOUR Centre","ror":"https://ror.org/01pwm0502","country_code":"CA","type":"other","lineage":["https://openalex.org/I4210111431"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Paul W. Armstrong","raw_affiliation_strings":["Canadian VIGOUR Centre, University of Alberta, Edmonton, AB, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Canadian VIGOUR Centre, University of Alberta, Edmonton, AB, Canada","institution_ids":["https://openalex.org/I154425047","https://openalex.org/I4210111431"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5043115715","display_name":"Carlo Di Mario","orcid":"https://orcid.org/0000-0002-4461-2055","observed_orcids":["https://orcid.org/0000-0002-4461-2055"]},"institutions":[{"id":"https://openalex.org/I4210096640","display_name":"Royal Brompton Hospital","ror":"https://ror.org/00cv4n034","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I2800036501","https://openalex.org/I4210096640"]},{"id":"https://openalex.org/I47508984","display_name":"Imperial College London","ror":"https://ror.org/041kmwe10","country_code":"GB","type":"education","lineage":["https://openalex.org/I47508984"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Carlo Di Mario","raw_affiliation_strings":["Royal Brompton Hospital and Imperial College, London, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Royal Brompton Hospital and Imperial College, London, UK","institution_ids":["https://openalex.org/I4210096640","https://openalex.org/I47508984"]}]}],"institutions":[],"countries_distinct_count":6,"institutions_distinct_count":15,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":5240,"currency":"EUR","value_usd":5922},"apc_paid":null,"fwci":3.5148,"has_fulltext":false,"cited_by_count":212,"citation_normalized_percentile":{"value":0.93093923,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":95,"max":100},"biblio":{"volume":"31","issue":"17","first_page":"2156","last_page":"2169"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10292","display_name":"Acute Myocardial Infarction Research","score":0.9711999893188477,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10292","display_name":"Acute Myocardial Infarction Research","score":0.9711999893188477,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10193","display_name":"Coronary Interventions and Diagnostics","score":0.025200000032782555,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11064","display_name":"Antiplatelet Therapy and Cardiovascular Diseases","score":0.0010000000474974513,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/st-elevation-myocardial-infarction","display_name":"ST-elevation myocardial infarction","score":0.9919999837875366},{"id":"https://openalex.org/keywords/percutaneous-coronary-intervention","display_name":"percutaneous coronary intervention","score":0.8899999856948853},{"id":"https://openalex.org/keywords/fibrinolysis","display_name":"fibrinolysis","score":0.9800000190734863},{"id":"https://openalex.org/keywords/early-invasive-strategy","display_name":"early invasive strategy","score":0.6620000004768372},{"id":"https://openalex.org/keywords/rescue-pci","display_name":"rescue PCI","score":0.8399999737739563},{"id":"https://openalex.org/keywords/recurrent-myocardial-infarction","display_name":"reinfarction","score":0.9200000166893005},{"id":"https://openalex.org/keywords/major-bleeding","display_name":"major bleeding","score":0.5220000147819519},{"id":"https://openalex.org/keywords/stroke","display_name":"stroke","score":0.6299999952316284},{"id":"https://openalex.org/keywords/mortality","display_name":"mortality","score":0.5419999957084656},{"id":"https://openalex.org/keywords/timing-of-revascularization","display_name":"timing of revascularization","score":0.7300000190734863},{"id":"https://openalex.org/keywords/thrombolysis","display_name":"thrombolysis","score":0.41200000047683716},{"id":"https://openalex.org/keywords/clopidogrel","display_name":"clopidogrel","score":0.5600000023841858},{"id":"https://openalex.org/keywords/aspirin","display_name":"aspirin","score":0.6119999885559082},{"id":"https://openalex.org/keywords/glycoprotein-iib-iiia-inhibitors","display_name":"glycoprotein IIb/IIIa inhibitors","score":0.777999997138977},{"id":"https://openalex.org/keywords/antiplatelet-therapy","display_name":"antiplatelet therapy","score":0.46299999952316284}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9872732162475586},{"id":"https://openalex.org/C2780400711","wikidata":"https://www.wikidata.org/wiki/Q2008344","display_name":"Percutaneous coronary intervention","level":3,"score":0.8521433472633362},{"id":"https://openalex.org/C2776825266","wikidata":"https://www.wikidata.org/wiki/Q1410794","display_name":"Fibrinolysis","level":2,"score":0.8133758306503296},{"id":"https://openalex.org/C164705383","wikidata":"https://www.wikidata.org/wiki/Q10379","display_name":"Cardiology","level":1,"score":0.7308196425437927},{"id":"https://openalex.org/C500558357","wikidata":"https://www.wikidata.org/wiki/Q12152","display_name":"Myocardial infarction","level":2,"score":0.7282593846321106},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.688034176826477},{"id":"https://openalex.org/C2771771","wikidata":"https://www.wikidata.org/wiki/Q6576883","display_name":"ST segment","level":3,"score":0.5237293839454651},{"id":"https://openalex.org/C2910604149","wikidata":"https://www.wikidata.org/wiki/Q1931577","display_name":"Fibrinolytic therapy","level":3,"score":0.48799556493759155},{"id":"https://openalex.org/C37054046","wikidata":"https://www.wikidata.org/wiki/Q641888","display_name":"Elevation (ballistics)","level":2,"score":0.4190237820148468},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.0},{"id":"https://openalex.org/C2524010","wikidata":"https://www.wikidata.org/wiki/Q8087","display_name":"Geometry","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D005343","descriptor_name":"Fibrinolytic Agents","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D005343","descriptor_name":"Fibrinolytic Agents","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D005343","descriptor_name":"Fibrinolytic Agents","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009203","descriptor_name":"Myocardial Infarction","qualifier_ui":"Q000401","qualifier_name":"mortality","is_major_topic":false},{"descriptor_ui":"D009203","descriptor_name":"Myocardial Infarction","qualifier_ui":"Q000401","qualifier_name":"mortality","is_major_topic":false},{"descriptor_ui":"D009203","descriptor_name":"Myocardial Infarction","qualifier_ui":"Q000401","qualifier_name":"mortality","is_major_topic":false},{"descriptor_ui":"D009203","descriptor_name":"Myocardial Infarction","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":false},{"descriptor_ui":"D009203","descriptor_name":"Myocardial Infarction","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":false},{"descriptor_ui":"D009203","descriptor_name":"Myocardial Infarction","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":false},{"descriptor_ui":"D009204","descriptor_name":"Myocardial Revascularization","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D009204","descriptor_name":"Myocardial Revascularization","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D009204","descriptor_name":"Myocardial Revascularization","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D009204","descriptor_name":"Myocardial Revascularization","qualifier_ui":"Q000401","qualifier_name":"mortality","is_major_topic":false},{"descriptor_ui":"D009204","descriptor_name":"Myocardial Revascularization","qualifier_ui":"Q000401","qualifier_name":"mortality","is_major_topic":false},{"descriptor_ui":"D009204","descriptor_name":"Myocardial Revascularization","qualifier_ui":"Q000401","qualifier_name":"mortality","is_major_topic":false},{"descriptor_ui":"D012008","descriptor_name":"Recurrence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012008","descriptor_name":"Recurrence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012008","descriptor_name":"Recurrence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015906","descriptor_name":"Angioplasty, Balloon, Coronary","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D015906","descriptor_name":"Angioplasty, Balloon, Coronary","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D015906","descriptor_name":"Angioplasty, Balloon, Coronary","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D015906","descriptor_name":"Angioplasty, Balloon, Coronary","qualifier_ui":"Q000401","qualifier_name":"mortality","is_major_topic":false},{"descriptor_ui":"D015906","descriptor_name":"Angioplasty, Balloon, Coronary","qualifier_ui":"Q000401","qualifier_name":"mortality","is_major_topic":false},{"descriptor_ui":"D015906","descriptor_name":"Angioplasty, Balloon, Coronary","qualifier_ui":"Q000401","qualifier_name":"mortality","is_major_topic":false},{"descriptor_ui":"D015912","descriptor_name":"Thrombolytic Therapy","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D015912","descriptor_name":"Thrombolytic Therapy","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D015912","descriptor_name":"Thrombolytic Therapy","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D015912","descriptor_name":"Thrombolytic Therapy","qualifier_ui":"Q000401","qualifier_name":"mortality","is_major_topic":false},{"descriptor_ui":"D015912","descriptor_name":"Thrombolytic Therapy","qualifier_ui":"Q000401","qualifier_name":"mortality","is_major_topic":false},{"descriptor_ui":"D015912","descriptor_name":"Thrombolytic Therapy","qualifier_ui":"Q000401","qualifier_name":"mortality","is_major_topic":false},{"descriptor_ui":"D016032","descriptor_name":"Randomized Controlled Trials as Topic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016032","descriptor_name":"Randomized Controlled Trials as Topic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016032","descriptor_name":"Randomized Controlled Trials as Topic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016896","descriptor_name":"Treatment Outcome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016896","descriptor_name":"Treatment Outcome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016896","descriptor_name":"Treatment Outcome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1093/eurheartj/ehq204","doi":"https://doi.org/10.1093/eurheartj/ehq204","is_oa":false,"landing_page_url":"https://doi.org/10.1093/eurheartj/ehq204","pdf_url":null,"source":{"id":"https://openalex.org/S181568219","display_name":"European Heart Journal","issn_l":"0195-668X","issn":["0195-668X","1522-9645"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"European Heart Journal","raw_type":"journal-article"},{"id":"pmid:20601393","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/20601393","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"European heart journal","raw_type":"Comparative Study"},{"id":"pmh:oai:flore.unifi.it:2158/1135981","doi":null,"is_oa":false,"landing_page_url":"http://hdl.handle.net/2158/1135981","pdf_url":null,"source":{"id":"https://openalex.org/S4306402033","display_name":"Florence Research (University of Florence)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I45084792","host_organization_name":"University of Florence","host_organization_lineage":["https://openalex.org/I45084792"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":1.0}],"sustainable_development_goals_aurora":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.8500000238418579}],"study_designs":[{"display_name":"Systematic Review","id":"https://openalex.org/study-designs/systematic-review"},{"display_name":"Meta-Analysis","id":"https://openalex.org/study-designs/meta-analysis"}],"awards":[],"funders":[{"id":"https://openalex.org/F4320334506","display_name":"Canadian Institutes of Health Research","ror":"https://ror.org/01gavpb45"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":42,"referenced_works":["https://openalex.org/W15231971","https://openalex.org/W24088030","https://openalex.org/W1519563600","https://openalex.org/W1520905029","https://openalex.org/W1922348626","https://openalex.org/W1966493516","https://openalex.org/W1968120780","https://openalex.org/W1986215651","https://openalex.org/W1990876610","https://openalex.org/W2000442546","https://openalex.org/W2004095900","https://openalex.org/W2011047627","https://openalex.org/W2056083953","https://openalex.org/W2075445774","https://openalex.org/W2079030174","https://openalex.org/W2088958446","https://openalex.org/W2093928145","https://openalex.org/W2104313731","https://openalex.org/W2112482963","https://openalex.org/W2113178124","https://openalex.org/W2117254307","https://openalex.org/W2118922883","https://openalex.org/W2121268836","https://openalex.org/W2122555614","https://openalex.org/W2130806602","https://openalex.org/W2134852288","https://openalex.org/W2135227162","https://openalex.org/W2137073380","https://openalex.org/W2147615829","https://openalex.org/W2148336869","https://openalex.org/W2149179865","https://openalex.org/W2154049887","https://openalex.org/W2159993752","https://openalex.org/W2164085712","https://openalex.org/W2164216179","https://openalex.org/W2170504268","https://openalex.org/W2322552681","https://openalex.org/W2368166910","https://openalex.org/W2412367806","https://openalex.org/W2523584376","https://openalex.org/W2616526627","https://openalex.org/W3033934470"],"related_works":["https://openalex.org/W4248134853","https://openalex.org/W2082020455","https://openalex.org/W2889921835","https://openalex.org/W2762338479","https://openalex.org/W2080137818","https://openalex.org/W2092523458","https://openalex.org/W4402736180","https://openalex.org/W2074213664","https://openalex.org/W3144615962","https://openalex.org/W2000035377"],"abstract_inverted_index":{"AIMS:":[0],"Multiple":[1],"trials":[2,36,55,77],"in":[3,62,95,115,179,219,248,264],"patients":[4,28,40,250],"with":[5,215,260],"ST-segment":[6],"elevation":[7],"myocardial":[8],"infarction":[9],"(STEMI)":[10],"compared":[11,268],"early":[12,83,274],"routine":[13,204,244],"percutaneous":[14],"coronary":[15],"intervention":[16],"(PCI)":[17],"after":[18,85,129,246],"successful":[19,130],"fibrinolysis":[20,42,86,131,247],"vs.":[21],"standard":[22,88,208,270],"therapy":[23,89,209],"limiting":[24],"PCI":[25,84,128,245,275],"only":[26],"to":[27,78,269],"without":[29,175],"evidence":[30],"of":[31,74,82,108,118,135,202,273],"reperfusion":[32],"(rescue":[33],"PCI).":[34],"These":[35,171],"suggest":[37],"that":[38],"all":[39],"receiving":[41],"should":[43],"receive":[44],"mechanical":[45],"revascularization":[46],"within":[47],"24":[48],"h":[49],"from":[50],"initial":[51],"hospitalization.":[52],"However,":[53],"individual":[54],"could":[56],"not":[57],"demonstrate":[58],"a":[59,72,106,176,203],"significant":[60,177,217,262],"reduction":[61,218],"'hard'":[63],"endpoints":[64,94,221],"such":[65],"as":[66],"death":[67,119],"and":[68,92,157,231,254],"reinfarction.":[69],"We":[70,100],"performed":[71],"meta-analysis":[73],"randomized":[75],"controlled":[76],"define":[79],"the":[80,116,124,133,145,220],"benefits":[81,201],"over":[87,207],"on":[90],"clinical":[91],"safety":[93],"STEMI.":[96],"METHODS":[97],"AND":[98],"RESULTS:":[99],"identified":[101],"seven":[102],"eligible":[103],"trials,":[104],"enrolling":[105],"total":[107],"2961":[109],"patients.":[110],"No":[111],"difference":[112],"was":[113],"found":[114],"incidence":[117],"at":[120,168,212,257,277],"30":[121],"days":[122],"between":[123],"two":[125],"strategies.":[126],"Early":[127,243],"reduced":[132,252],"rate":[134],"reinfarction":[136,222,253],"(OR:":[137,149,160,182,192,223,234],"0.55,":[138],"95%":[139,151,162,194,225,236],"CI:":[140,152,163,185,195,226,237],"0.36-0.82;":[141],"P":[142,154,165,187,197,228,239],"=":[143,155,188,198,229,240],"0.003),":[144],"combined":[146,232],"endpoint":[147],"death/reinfarction":[148,233],"0.65,":[150],"0.49-0.88;":[153],"0.004)":[156],"recurrent":[158,255],"ischaemia":[159,256],"0.25,":[161],"0.13-0.49;":[164],"<":[166],"0.001)":[167],"30-day":[169],"follow-up.":[170,280],"advantages":[172],"were":[173,210],"achieved":[174],"increase":[178,263],"major":[180],"bleeding":[181,266],"0.93,":[183],"96%":[184],"0.67-1.34;":[186],"0.70)":[189],"or":[190],"stroke":[191],"0.63,":[193],"0.31-1.26;":[196],"0.21).":[199],"The":[200],"invasive":[205],"strategy":[206],"maintained":[211],"6-12":[213,278],"months,":[214],"persistent":[216],"0.64,":[224],"0.40-0.98;":[227],"0.01)":[230],"0.71,":[235],"0.52-0.97;":[238],"0.03).":[241],"CONCLUSION:":[242],"STEMI":[249],"significantly":[251],"1":[258],"month,":[259],"no":[261],"adverse":[265],"events":[267],"therapy.":[271],"Benefits":[272],"persist":[276],"month":[279]},"counts_by_year":[{"year":2026,"cited_by_count":5},{"year":2025,"cited_by_count":6},{"year":2024,"cited_by_count":5},{"year":2023,"cited_by_count":7},{"year":2022,"cited_by_count":3},{"year":2021,"cited_by_count":14},{"year":2020,"cited_by_count":10},{"year":2019,"cited_by_count":12},{"year":2018,"cited_by_count":9},{"year":2017,"cited_by_count":13},{"year":2016,"cited_by_count":17},{"year":2015,"cited_by_count":10},{"year":2014,"cited_by_count":27},{"year":2013,"cited_by_count":15},{"year":2012,"cited_by_count":26}],"updated_date":"2026-10-16T09:59:22.235173","created_date":"2025-10-10T00:00:00"}