{"id":"https://openalex.org/W2126953591","doi":"https://doi.org/10.4065/75.4.369","title":"Novel Risk Factors for Atherosclerosis","display_name":"Novel Risk Factors for Atherosclerosis","publication_year":2000,"publication_date":"2000-04-01","ids":{"openalex":"https://openalex.org/W2126953591","doi":"https://doi.org/10.4065/75.4.369","mag":"2126953591","pmid":"https://pubmed.ncbi.nlm.nih.gov/10761492"},"language":"en","primary_location":{"id":"doi:10.4065/75.4.369","doi":"https://doi.org/10.4065/75.4.369","is_oa":false,"landing_page_url":"https://doi.org/10.4065/75.4.369","pdf_url":null,"source":{"id":"https://openalex.org/S58241369","display_name":"Mayo Clinic Proceedings","issn_l":"0025-6196","issn":["0025-6196","1942-5546"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Mayo Clinic Proceedings","raw_type":"journal-article"},"volume":null,"type":"review","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5065025844","display_name":"Iftikhar J. Kullo","orcid":"https://orcid.org/0000-0002-6524-3471","observed_orcids":["https://orcid.org/0000-0002-6524-3471"]},"institutions":[{"id":"https://openalex.org/I1330342723","display_name":"Mayo Clinic","ror":"https://ror.org/02qp3tb03","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1330342723"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Iftikhar J. Kullo","raw_affiliation_strings":["Division of Cardiovascular Diseases, Mayo Clinic Rochester, Minn. 55905, USA","Division of Cardiovascular Diseases and internal Medicine, Mayo Clinic Rochester, Rochester, Minn"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Cardiovascular Diseases, Mayo Clinic Rochester, Minn. 55905, USA","institution_ids":["https://openalex.org/I1330342723"]},{"raw_affiliation_string":"Division of Cardiovascular Diseases and internal Medicine, Mayo Clinic Rochester, Rochester, Minn","institution_ids":["https://openalex.org/I1330342723"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5071327112","display_name":"Gerald T. Gau","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1330342723","display_name":"Mayo Clinic","ror":"https://ror.org/02qp3tb03","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1330342723"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Gerald T. Gau","raw_affiliation_strings":["Division of Cardiovascular Diseases and Internal Medicine, Mayo Clinic Rochester, Rochester, Minn"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Cardiovascular Diseases and Internal Medicine, Mayo Clinic Rochester, Rochester, Minn","institution_ids":["https://openalex.org/I1330342723"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5054351656","display_name":"Abdul Jamil Tajik","orcid":"https://orcid.org/0000-0002-4784-1275","observed_orcids":["https://orcid.org/0000-0002-4784-1275"]},"institutions":[{"id":"https://openalex.org/I1330342723","display_name":"Mayo Clinic","ror":"https://ror.org/02qp3tb03","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1330342723"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"A. Jamil Tajik","raw_affiliation_strings":["Division of Cardiovascular Diseases and Internal Medicine, Mayo Clinic Rochester, Rochester, Minn"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Cardiovascular Diseases and Internal Medicine, Mayo Clinic Rochester, Rochester, Minn","institution_ids":["https://openalex.org/I1330342723"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5065025844"],"corresponding_institution_ids":["https://openalex.org/I1330342723"],"apc_list":{"value":3900,"currency":"USD","value_usd":3900},"apc_paid":null,"fwci":4.2329,"has_fulltext":false,"cited_by_count":160,"citation_normalized_percentile":{"value":0.97068063,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":88,"max":99},"biblio":{"volume":"75","issue":"4","first_page":"369","last_page":"380"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10394","display_name":"Lipoproteins and Cardiovascular Health","score":0.9082000255584717,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10394","display_name":"Lipoproteins and Cardiovascular Health","score":0.9082000255584717,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12955","display_name":"Atherosclerosis and Cardiovascular Diseases","score":0.03550000116229057,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T13522","display_name":"Cardiovascular Health and Risk Factors","score":0.018699999898672104,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/atherosclerosis","display_name":"atherosclerosis","score":0.972000002861023},{"id":"https://openalex.org/keywords/novel-risk-factors","display_name":"novel risk factors","score":0.972000002861023},{"id":"https://openalex.org/keywords/homocysteine","display_name":"homocysteine","score":0.9150000214576721},{"id":"https://openalex.org/keywords/fibrinogen","display_name":"fibrinogen","score":0.9990000128746033},{"id":"https://openalex.org/keywords/impaired-fibrinolysis","display_name":"impaired fibrinolysis","score":0.984000027179718},{"id":"https://openalex.org/keywords/platelet-reactivity","display_name":"platelet reactivity","score":0.9769999980926514},{"id":"https://openalex.org/keywords/hypercoagulability","display_name":"hypercoagulability","score":0.9990000128746033},{"id":"https://openalex.org/keywords/lipoprotein-a","display_name":"lipoprotein(a)","score":1.0},{"id":"https://openalex.org/keywords/small-dense-ldl","display_name":"small dense LDL","score":0.875},{"id":"https://openalex.org/keywords/inflammatory-markers","display_name":"inflammatory markers","score":0.9750000238418579},{"id":"https://openalex.org/keywords/ethnic-differences","display_name":"ethnic differences","score":0.6890000104904175},{"id":"https://openalex.org/keywords/cardiovascular-risk-prediction","display_name":"cardiovascular risk prediction","score":0.6259999871253967},{"id":"https://openalex.org/keywords/atherogenesis","display_name":"atherogenesis","score":0.8389999866485596}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9051221609115601},{"id":"https://openalex.org/C2779036427","wikidata":"https://www.wikidata.org/wiki/Q381899","display_name":"Fibrinogen","level":2,"score":0.6691159605979919},{"id":"https://openalex.org/C2776825266","wikidata":"https://www.wikidata.org/wiki/Q1410794","display_name":"Fibrinolysis","level":2,"score":0.6221044659614563},{"id":"https://openalex.org/C50440223","wikidata":"https://www.wikidata.org/wiki/Q1475848","display_name":"Risk factor","level":2,"score":0.579157292842865},{"id":"https://openalex.org/C2780942790","wikidata":"https://www.wikidata.org/wiki/Q372016","display_name":"Pathogenesis","level":2,"score":0.5581047534942627},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.5550143718719482},{"id":"https://openalex.org/C2777090595","wikidata":"https://www.wikidata.org/wiki/Q192466","display_name":"Homocysteine","level":2,"score":0.47221142053604126},{"id":"https://openalex.org/C2776104379","wikidata":"https://www.wikidata.org/wiki/Q21112670","display_name":"Lipoprotein(a)","level":4,"score":0.46855220198631287},{"id":"https://openalex.org/C2777466421","wikidata":"https://www.wikidata.org/wiki/Q1266890","display_name":"Vascular disease","level":2,"score":0.4539310038089752},{"id":"https://openalex.org/C2780072125","wikidata":"https://www.wikidata.org/wiki/Q28350","display_name":"Lipoprotein","level":3,"score":0.40121275186538696},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.4003854990005493},{"id":"https://openalex.org/C60644358","wikidata":"https://www.wikidata.org/wiki/Q128570","display_name":"Bioinformatics","level":1,"score":0.38262027502059937},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.31112855672836304},{"id":"https://openalex.org/C2778163477","wikidata":"https://www.wikidata.org/wiki/Q43656","display_name":"Cholesterol","level":2,"score":0.283124178647995},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D001161","descriptor_name":"Arteriosclerosis","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D001161","descriptor_name":"Arteriosclerosis","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":true},{"descriptor_ui":"D001778","descriptor_name":"Blood Coagulation Disorders","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D001778","descriptor_name":"Blood Coagulation Disorders","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":false},{"descriptor_ui":"D001792","descriptor_name":"Blood Platelets","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D002097","descriptor_name":"C-Reactive Protein","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D005340","descriptor_name":"Fibrinogen","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D005342","descriptor_name":"Fibrinolysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006710","descriptor_name":"Homocysteine","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007239","descriptor_name":"Infections","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":false},{"descriptor_ui":"D007249","descriptor_name":"Inflammation","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":false},{"descriptor_ui":"D008078","descriptor_name":"Cholesterol, LDL","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D012307","descriptor_name":"Risk Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015415","descriptor_name":"Biomarkers","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D017270","descriptor_name":"Lipoprotein(a)","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D018799","descriptor_name":"Intercellular Adhesion Molecule-1","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.4065/75.4.369","doi":"https://doi.org/10.4065/75.4.369","is_oa":false,"landing_page_url":"https://doi.org/10.4065/75.4.369","pdf_url":null,"source":{"id":"https://openalex.org/S58241369","display_name":"Mayo Clinic Proceedings","issn_l":"0025-6196","issn":["0025-6196","1942-5546"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Mayo Clinic Proceedings","raw_type":"journal-article"},{"id":"pmid:10761492","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/10761492","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Mayo Clinic proceedings","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.9940000176429749,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":165,"referenced_works":["https://openalex.org/W202019503","https://openalex.org/W628637055","https://openalex.org/W1485388354","https://openalex.org/W1557771952","https://openalex.org/W1643340059","https://openalex.org/W1651383390","https://openalex.org/W1767446315","https://openalex.org/W1874911532","https://openalex.org/W1920976164","https://openalex.org/W1963521889","https://openalex.org/W1964867773","https://openalex.org/W1965791931","https://openalex.org/W1966292733","https://openalex.org/W1967328004","https://openalex.org/W1969138367","https://openalex.org/W1969277115","https://openalex.org/W1972729110","https://openalex.org/W1973178110","https://openalex.org/W1974009374","https://openalex.org/W1975357252","https://openalex.org/W1975375149","https://openalex.org/W1976976563","https://openalex.org/W1977349752","https://openalex.org/W1978128973","https://openalex.org/W1978796955","https://openalex.org/W1980619762","https://openalex.org/W1980840278","https://openalex.org/W1981594756","https://openalex.org/W1981638570","https://openalex.org/W1982518535","https://openalex.org/W1983055162","https://openalex.org/W1988414136","https://openalex.org/W1989069669","https://openalex.org/W1989755277","https://openalex.org/W1991325639","https://openalex.org/W1991977311","https://openalex.org/W1992225083","https://openalex.org/W1993145269","https://openalex.org/W1995490941","https://openalex.org/W1996545786","https://openalex.org/W1996810831","https://openalex.org/W1999233620","https://openalex.org/W2003972235","https://openalex.org/W2004188989","https://openalex.org/W2004893917","https://openalex.org/W2007332542","https://openalex.org/W2010353121","https://openalex.org/W2010545674","https://openalex.org/W2010933740","https://openalex.org/W2011589019","https://openalex.org/W2012873234","https://openalex.org/W2013521697","https://openalex.org/W2017226660","https://openalex.org/W2019145889","https://openalex.org/W2024991598","https://openalex.org/W2027358064","https://openalex.org/W2029136751","https://openalex.org/W2031374350","https://openalex.org/W2032524811","https://openalex.org/W2036527519","https://openalex.org/W2037850697","https://openalex.org/W2038423691","https://openalex.org/W2039831544","https://openalex.org/W2039876041","https://openalex.org/W2042368323","https://openalex.org/W2043951336","https://openalex.org/W2046367794","https://openalex.org/W2047975147","https://openalex.org/W2049138031","https://openalex.org/W2049731130","https://openalex.org/W2049967476","https://openalex.org/W2050758709","https://openalex.org/W2050983178","https://openalex.org/W2053802334","https://openalex.org/W2053868688","https://openalex.org/W2060132183","https://openalex.org/W2060848125","https://openalex.org/W2061940963","https://openalex.org/W2066886181","https://openalex.org/W2069750854","https://openalex.org/W2070225053","https://openalex.org/W2073283371","https://openalex.org/W2074914768","https://openalex.org/W2075481359","https://openalex.org/W2076500453","https://openalex.org/W2076907458","https://openalex.org/W2077161201","https://openalex.org/W2078769171","https://openalex.org/W2080946269","https://openalex.org/W2082803118","https://openalex.org/W2085713634","https://openalex.org/W2085959182","https://openalex.org/W2086539673","https://openalex.org/W2088959855","https://openalex.org/W2089205356","https://openalex.org/W2089286420","https://openalex.org/W2090845578","https://openalex.org/W2100367705","https://openalex.org/W2103833102","https://openalex.org/W2106837301","https://openalex.org/W2109116473","https://openalex.org/W2110807383","https://openalex.org/W2111530455","https://openalex.org/W2112722571","https://openalex.org/W2113846203","https://openalex.org/W2118015493","https://openalex.org/W2119236594","https://openalex.org/W2120549911","https://openalex.org/W2122553993","https://openalex.org/W2123853270","https://openalex.org/W2125047098","https://openalex.org/W2130780306","https://openalex.org/W2131581679","https://openalex.org/W2131594005","https://openalex.org/W2135479614","https://openalex.org/W2135568455","https://openalex.org/W2137570167","https://openalex.org/W2138809584","https://openalex.org/W2142419120","https://openalex.org/W2144238512","https://openalex.org/W2144604930","https://openalex.org/W2146733308","https://openalex.org/W2148519998","https://openalex.org/W2151482800","https://openalex.org/W2152086330","https://openalex.org/W2152445890","https://openalex.org/W2154032259","https://openalex.org/W2156158060","https://openalex.org/W2157251990","https://openalex.org/W2158475008","https://openalex.org/W2158896434","https://openalex.org/W2159389024","https://openalex.org/W2161714011","https://openalex.org/W2163635805","https://openalex.org/W2164001662","https://openalex.org/W2167033150","https://openalex.org/W2167779923","https://openalex.org/W2169303393","https://openalex.org/W2170750385","https://openalex.org/W2171101087","https://openalex.org/W2183193914","https://openalex.org/W2187104826","https://openalex.org/W2266911869","https://openalex.org/W2278594452","https://openalex.org/W2314055786","https://openalex.org/W2315575691","https://openalex.org/W2316376271","https://openalex.org/W2317172136","https://openalex.org/W2330126172","https://openalex.org/W2332685851","https://openalex.org/W2336672206","https://openalex.org/W2337184574","https://openalex.org/W2394858131","https://openalex.org/W2404154866","https://openalex.org/W2413959424","https://openalex.org/W2415131613","https://openalex.org/W2417377791","https://openalex.org/W2430094842","https://openalex.org/W2440874100","https://openalex.org/W4211007417","https://openalex.org/W4245566103","https://openalex.org/W4253302910","https://openalex.org/W4255283125","https://openalex.org/W4285719527","https://openalex.org/W4294570513"],"related_works":["https://openalex.org/W2105961816","https://openalex.org/W2083564224","https://openalex.org/W2410895413","https://openalex.org/W2588815537","https://openalex.org/W2027086504","https://openalex.org/W2131278381","https://openalex.org/W2581582602","https://openalex.org/W1484250550","https://openalex.org/W4392095863","https://openalex.org/W2324367408"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":1},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":2},{"year":2019,"cited_by_count":2},{"year":2017,"cited_by_count":2},{"year":2016,"cited_by_count":3},{"year":2015,"cited_by_count":3},{"year":2014,"cited_by_count":3},{"year":2013,"cited_by_count":4},{"year":2012,"cited_by_count":7}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}
