{"id":"https://openalex.org/W21266409","doi":null,"title":"Prenatal diagnosis of congenital rubella infection and ultrasonography: a preliminary study.","display_name":"Prenatal diagnosis of congenital rubella infection and ultrasonography: a preliminary study.","publication_year":2011,"publication_date":"2011-12-01","ids":{"openalex":"https://openalex.org/W21266409","mag":"21266409","pmid":"https://pubmed.ncbi.nlm.nih.gov/22036752"},"language":"en","primary_location":{"id":"pmid:22036752","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/22036752","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Minerva ginecologica","raw_type":"Journal Article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5044537955","display_name":"Annalisa Migliucci","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210117450","display_name":"Federico II University Hospital","ror":"https://ror.org/02jr6tp70","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210117450","https://openalex.org/I71267560"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"A Migliucci","raw_affiliation_strings":["Department of Obstetrics and Gynecology, University Hospital Federico II, Naples, Italy. annalisa.migliucci@gmail.com"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Obstetrics and Gynecology, University Hospital Federico II, Naples, Italy. annalisa.migliucci@gmail.com","institution_ids":["https://openalex.org/I4210117450"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5067572243","display_name":"D. Di Fraja","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"D Di Fraja","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5090244927","display_name":"Laura Sarno","orcid":"https://orcid.org/0000-0002-5578-2885","observed_orcids":["https://orcid.org/0000-0002-5578-2885"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"L Sarno","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5039329284","display_name":"Eleonora Acampora","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"E Acampora","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5114090261","display_name":"Laura Letizia Mazzarelli","orcid":"https://orcid.org/0000-0002-1314-2812","observed_orcids":["https://orcid.org/0000-0002-1314-2812"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"L L Mazzarelli","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5087995853","display_name":"Filomena Quaglia","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"F Quaglia","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5007486599","display_name":"Giovanna Mallia Milanes","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"G Mallia Milanes","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5030458355","display_name":"Wilma Buffolano","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"W Buffolano","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5062442962","display_name":"R. Napolitano","orcid":"https://orcid.org/0000-0001-9434-7678","observed_orcids":["https://orcid.org/0000-0001-9434-7678","https://orcid.org/0000-0002-8512-2597"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"R Napolitano","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111157958","display_name":"S. Simioli","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"S Simioli","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5029708408","display_name":"Giuseppe Maria Maruotti","orcid":"https://orcid.org/0000-0002-9666-6338","observed_orcids":["https://orcid.org/0000-0002-9666-6338"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"G M Maruotti","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":null,"display_name":"P Martinelli","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"P Martinelli","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.2174,"has_fulltext":false,"cited_by_count":8,"citation_normalized_percentile":{"value":0.56250931,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":95},"biblio":{"volume":"63","issue":"6","first_page":"485","last_page":"9"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11135","display_name":"Virology and Viral Diseases","score":0.7598000168800354,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11135","display_name":"Virology and Viral Diseases","score":0.7598000168800354,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10978","display_name":"Prenatal Screening and Diagnostics","score":0.07079999893903732,"subfield":{"id":"https://openalex.org/subfields/2735","display_name":"Pediatrics, Perinatology and Child Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12849","display_name":"Parvovirus B19 Infection Studies","score":0.046799998730421066,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/congenital-rubella-syndrome","display_name":"congenital rubella syndrome","score":0.968999981880188},{"id":"https://openalex.org/keywords/prenatal-diagnosis","display_name":"prenatal diagnosis","score":0.8090000152587891},{"id":"https://openalex.org/keywords/rubella-in-pregnancy","display_name":"rubella infection in pregnancy","score":0.9309999942779541},{"id":"https://openalex.org/keywords/prenatal-ultrasound","display_name":"prenatal ultrasound","score":0.8190000057220459},{"id":"https://openalex.org/keywords/fetal-malformations","display_name":"fetal malformations","score":0.5870000123977661},{"id":"https://openalex.org/keywords/neonatal-outcomes","display_name":"neonatal outcomes","score":0.7210000157356262},{"id":"https://openalex.org/keywords/intrauterine-infection","display_name":"intrauterine infection","score":0.7940000295639038},{"id":"https://openalex.org/keywords/sensitivity-and-specificity","display_name":"sensitivity and specificity","score":0.7490000128746033}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9573647379875183},{"id":"https://openalex.org/C2778814567","wikidata":"https://www.wikidata.org/wiki/Q155857","display_name":"Rubella","level":4,"score":0.8432855606079102},{"id":"https://openalex.org/C2779234561","wikidata":"https://www.wikidata.org/wiki/Q11995","display_name":"Pregnancy","level":2,"score":0.6769055128097534},{"id":"https://openalex.org/C131872663","wikidata":"https://www.wikidata.org/wiki/Q5284418","display_name":"Obstetrics","level":1,"score":0.5862371921539307},{"id":"https://openalex.org/C2778097271","wikidata":"https://www.wikidata.org/wiki/Q701609","display_name":"Rubella virus","level":5,"score":0.5551406145095825},{"id":"https://openalex.org/C2778258057","wikidata":"https://www.wikidata.org/wiki/Q1136569","display_name":"Prenatal diagnosis","level":4,"score":0.5401282906532288},{"id":"https://openalex.org/C2776909254","wikidata":"https://www.wikidata.org/wiki/Q1724539","display_name":"Congenital rubella syndrome","level":5,"score":0.5249326825141907},{"id":"https://openalex.org/C2779440204","wikidata":"https://www.wikidata.org/wiki/Q1260186","display_name":"Hepatosplenomegaly","level":3,"score":0.524802565574646},{"id":"https://openalex.org/C2777910003","wikidata":"https://www.wikidata.org/wiki/Q1707292","display_name":"Asymptomatic","level":2,"score":0.5180152058601379},{"id":"https://openalex.org/C187212893","wikidata":"https://www.wikidata.org/wiki/Q123028","display_name":"Pediatrics","level":1,"score":0.4998776912689209},{"id":"https://openalex.org/C2908647359","wikidata":"https://www.wikidata.org/wiki/Q2625603","display_name":"Population","level":2,"score":0.4950844347476959},{"id":"https://openalex.org/C2909275681","wikidata":"https://www.wikidata.org/wiki/Q1724539","display_name":"Congenital Rubella","level":5,"score":0.4348353147506714},{"id":"https://openalex.org/C172680121","wikidata":"https://www.wikidata.org/wiki/Q26513","display_name":"Fetus","level":3,"score":0.32657337188720703},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.21615353226661682},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.2108001410961151},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.18752527236938477},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.1817050576210022},{"id":"https://openalex.org/C22070199","wikidata":"https://www.wikidata.org/wiki/Q192995","display_name":"Vaccination","level":2,"score":0.13181406259536743},{"id":"https://openalex.org/C2776438120","wikidata":"https://www.wikidata.org/wiki/Q79793","display_name":"Measles","level":3,"score":0.11089348793029785},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0},{"id":"https://openalex.org/C99454951","wikidata":"https://www.wikidata.org/wiki/Q932068","display_name":"Environmental health","level":1,"score":0.0},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011247","descriptor_name":"Pregnancy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011251","descriptor_name":"Pregnancy Complications, Infectious","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012189","descriptor_name":"Retrospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012409","descriptor_name":"Rubella","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012410","descriptor_name":"Rubella Syndrome, Congenital","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":true},{"descriptor_ui":"D016216","descriptor_name":"Ultrasonography, Prenatal","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":2,"locations":[{"id":"pmid:22036752","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/22036752","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Minerva ginecologica","raw_type":"Journal Article"},{"id":"mag:21266409","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/22036752","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"score":1.0,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":66,"referenced_works":["https://openalex.org/W1991055676","https://openalex.org/W2083502177","https://openalex.org/W1955270697","https://openalex.org/W2089200695","https://openalex.org/W2022133633","https://openalex.org/W2162942244","https://openalex.org/W2013935392","https://openalex.org/W2055064474","https://openalex.org/W2094892629","https://openalex.org/W1979330829","https://openalex.org/W2031683488","https://openalex.org/W2068867464","https://openalex.org/W2050071487","https://openalex.org/W2144773349","https://openalex.org/W2018682447","https://openalex.org/W2092684208","https://openalex.org/W2110287546","https://openalex.org/W1754645121","https://openalex.org/W1964891005","https://openalex.org/W2063317702","https://openalex.org/W2050753752","https://openalex.org/W2133943800","https://openalex.org/W2093007558","https://openalex.org/W2082694975","https://openalex.org/W162717576","https://openalex.org/W1993000387","https://openalex.org/W2061331078","https://openalex.org/W2043913581","https://openalex.org/W2050863097","https://openalex.org/W1898205487","https://openalex.org/W1981780292","https://openalex.org/W2076110149","https://openalex.org/W2125494710","https://openalex.org/W2043765395","https://openalex.org/W6664941767","https://openalex.org/W2004467363","https://openalex.org/W1987537120","https://openalex.org/W2006723548","https://openalex.org/W2012708732","https://openalex.org/W1547150431","https://openalex.org/W2064574277","https://openalex.org/W1996822975","https://openalex.org/W2076074295","https://openalex.org/W2000354146","https://openalex.org/W1995235203","https://openalex.org/W2133274339","https://openalex.org/W1953633452","https://openalex.org/W2099878990","https://openalex.org/W1995714714","https://openalex.org/W2086693994","https://openalex.org/W2033763031","https://openalex.org/W2083703722","https://openalex.org/W2115462348","https://openalex.org/W2077380101","https://openalex.org/W2054599163","https://openalex.org/W2067732706","https://openalex.org/W2083916541","https://openalex.org/W2167871550","https://openalex.org/W2067164989","https://openalex.org/W1993537286","https://openalex.org/W2142106234","https://openalex.org/W2059973092","https://openalex.org/W1542932778","https://openalex.org/W1910819802","https://openalex.org/W1983481075","https://openalex.org/W1580667945"],"related_works":["https://openalex.org/W2061007215","https://openalex.org/W2088904555","https://openalex.org/W4944992","https://openalex.org/W2324559542","https://openalex.org/W7119432013","https://openalex.org/W2073809881","https://openalex.org/W1971576456","https://openalex.org/W3011092085","https://openalex.org/W2096468510","https://openalex.org/W2093793099"],"abstract_inverted_index":{"AIM:":[0],"The":[1,101,223],"aim":[2],"of":[3,11,17,39,44,63,70,77,141,158,163,189,220,229,233],"this":[4],"study":[5,31],"was":[6,201],"to":[7,36,108,123,155],"analyze":[8],"the":[9,14,52,142,156,161,213,227],"role":[10,211],"ultrasonography":[12],"in":[13,23,42,51,93,112,160,212,218,231],"prenatal":[15,75,180],"diagnosis":[16],"women":[18,34,105],"with":[19,125],"confirmed":[20,61,91,126],"rubella":[21,49,97,110,127,134,151,181,215],"infection":[22,64,98,111,182,217],"pregnancy.":[24,113],"METHODS:":[25],"We":[26],"performed":[27,66],"a":[28,176],"retrospective,":[29],"population-based":[30],"on":[32],"175":[33,86],"referred":[35],"our":[37],"Centre":[38],"Infectious":[40],"Disease":[41],"Pregnancy":[43],"AOU":[45],"Federico":[46],"II":[47],"for":[48,74],"infection,":[50,128],"period":[53],"between":[54],"January":[55],"1999":[56],"and":[57,199,203,235],"December":[58],"2009.":[59],"In":[60,136],"cases":[62,96,117],"we":[65],"periodic":[67],"ultrasonographic":[68],"assessment":[69],"fetal":[71],"anatomy":[72],"looking":[73],"findings":[76,183],"rubeovirus":[78],"infection.":[79],"Neonatal":[80],"outcomes":[81],"were":[82,90,106,118,144,184],"collected.":[83],"RESULTS:":[84],"Among":[85,120],"women,":[87],"48":[88],"(27.4%)":[89],"cases,":[92],"83":[94],"(47.4%)":[95],"remain":[99],"suspected.":[100],"remaining":[102],"44":[103],"(25.1%)":[104],"excluded":[107],"having":[109],"No":[114],"defined":[115],"probable":[116],"found.":[119],"children":[121],"born":[122],"mother":[124],"9":[129],"(18.7%)":[130],"resulted":[131],"infected":[132],"by":[133],"virus.":[135],"particular":[137],"6":[138],"newborns":[139],"(66%":[140],"affected)":[143],"asymptomatic,":[145],"two":[146],"babies":[147],"showed":[148,175],"incomplete":[149],"congenital":[150,165],"syndrome":[152],"(CRS),":[153],"due":[154],"presence":[157],"deafness":[159,234],"absence":[162],"other":[164],"abnormalities":[166],"without":[167],"showing":[168],"any":[169],"USG":[170,179,197,207],"findings.":[171],"Only":[172],"one":[173],"baby":[174],"complete":[177],"CRS:":[178],"IUGR,":[185],"polydramnios,":[186],"cardiomegaly,":[187],"defects":[188],"atrial":[190],"septum,":[191],"hepatosplenomegaly,":[192],"ascites,":[193],"echogenic":[194],"bowel,":[195],"placentomegaly.":[196],"specificity":[198],"sensitivity":[200],"100%":[202],"11%":[204],"respectively.":[205],"CONCLUSION:":[206],"has":[208],"an":[209],"important":[210],"detection":[214,232],"intrauterine":[216],"case":[219],"severe":[221],"abnormalities.":[222,237],"obstetricians":[224],"should":[225],"understand":[226],"limitations":[228],"ultrasound":[230],"minor":[236]},"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2022,"cited_by_count":2},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":1},{"year":2018,"cited_by_count":1},{"year":2016,"cited_by_count":1},{"year":2014,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}