{"id":"https://openalex.org/W2126414770","doi":"https://doi.org/10.1016/s0168-9525(99)01776-x","title":"Pax 6: mastering eye morphogenesis and eye evolution","display_name":"Pax 6: mastering eye morphogenesis and eye evolution","publication_year":1999,"publication_date":"1999-09-01","ids":{"openalex":"https://openalex.org/W2126414770","doi":"https://doi.org/10.1016/s0168-9525(99)01776-x","mag":"2126414770","pmid":"https://pubmed.ncbi.nlm.nih.gov/10461206"},"language":"en","primary_location":{"id":"doi:10.1016/s0168-9525(99)01776-x","doi":"https://doi.org/10.1016/s0168-9525(99)01776-x","is_oa":false,"landing_page_url":"https://doi.org/10.1016/s0168-9525(99)01776-x","pdf_url":null,"source":{"id":"https://openalex.org/S139283865","display_name":"Trends in Genetics","issn_l":"0168-9525","issn":["0168-9525","1362-4555"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Trends in Genetics","raw_type":"journal-article"},"volume":null,"type":"review","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5043373700","display_name":"Walter J. Gehring","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1850255","display_name":"University of Basel","ror":"https://ror.org/02s6k3f65","country_code":"CH","type":"education","lineage":["https://openalex.org/I1850255"]}],"countries":["CH"],"is_corresponding":true,"raw_author_name":"Walter J Gehring","raw_affiliation_strings":["Department of Cell Biology, Biozentrum, University of Basel, Klingelbergstrasse 70, 4056 Basel, Switzerland. gehring@ubaclu.unibas.ch","Department of Cell Biology, Biozentrum, University of Basel, Klingelbergstrasse 70, 4056 Basel, Switzerland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cell Biology, Biozentrum, University of Basel, Klingelbergstrasse 70, 4056 Basel, Switzerland. gehring@ubaclu.unibas.ch","institution_ids":["https://openalex.org/I1850255"]},{"raw_affiliation_string":"Department of Cell Biology, Biozentrum, University of Basel, Klingelbergstrasse 70, 4056 Basel, Switzerland","institution_ids":["https://openalex.org/I1850255"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5049726104","display_name":"Kazuho Ikeo","orcid":"https://orcid.org/0000-0003-2446-6318","observed_orcids":["https://orcid.org/0000-0003-2446-6318"]},"institutions":[{"id":"https://openalex.org/I113198587","display_name":"National Institute of Genetics","ror":"https://ror.org/02xg1m795","country_code":"JP","type":"facility","lineage":["https://openalex.org/I113198587","https://openalex.org/I1319490839","https://openalex.org/I4210158934"]}],"countries":["JP"],"is_corresponding":true,"raw_author_name":"Kazuho Ikeo","raw_affiliation_strings":["Center for Information Biology, National Institute of Genetics, Mishima, Yata 411, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Information Biology, National Institute of Genetics, Mishima, Yata 411, Japan","institution_ids":["https://openalex.org/I113198587"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5043373700","https://openalex.org/A5049726104"],"corresponding_institution_ids":["https://openalex.org/I113198587","https://openalex.org/I1850255"],"apc_list":{"value":7030,"currency":"USD","value_usd":7030},"apc_paid":null,"fwci":3.0079,"has_fulltext":false,"cited_by_count":761,"citation_normalized_percentile":{"value":0.93463143,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":99,"max":100},"biblio":{"volume":"15","issue":"9","first_page":"371","last_page":"377"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10268","display_name":"Developmental Biology and Gene Regulation","score":0.9570000171661377,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10268","display_name":"Developmental Biology and Gene Regulation","score":0.9570000171661377,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12989","display_name":"Ocular Disorders and Treatments","score":0.03420000150799751,"subfield":{"id":"https://openalex.org/subfields/2731","display_name":"Ophthalmology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10691","display_name":"Retinal Development and Disorders","score":0.004100000020116568,"subfield":{"id":"https://openalex.org/subfields/2731","display_name":"Ophthalmology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/pax6","display_name":"Pax6","score":0.9470000267028809},{"id":"https://openalex.org/keywords/eye-morphogenesis","display_name":"eye morphogenesis","score":0.968999981880188},{"id":"https://openalex.org/keywords/eye-evolution","display_name":"eye evolution","score":0.996999979019165}],"concepts":[{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.9033860564231873},{"id":"https://openalex.org/C40692019","wikidata":"https://www.wikidata.org/wiki/Q815547","display_name":"Morphogenesis","level":3,"score":0.8341970443725586},{"id":"https://openalex.org/C114696181","wikidata":"https://www.wikidata.org/wiki/Q5422650","display_name":"Eye development","level":4,"score":0.7437757253646851},{"id":"https://openalex.org/C89611455","wikidata":"https://www.wikidata.org/wiki/Q6804646","display_name":"Mechanism (biology)","level":2,"score":0.551047682762146},{"id":"https://openalex.org/C2909722775","wikidata":"https://www.wikidata.org/wiki/Q942537","display_name":"Compound eye","level":2,"score":0.4829499125480652},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.41393402218818665},{"id":"https://openalex.org/C78458016","wikidata":"https://www.wikidata.org/wiki/Q840400","display_name":"Evolutionary biology","level":1,"score":0.33275219798088074},{"id":"https://openalex.org/C105702510","wikidata":"https://www.wikidata.org/wiki/Q514","display_name":"Anatomy","level":1,"score":0.32416456937789917},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.2942991256713867},{"id":"https://openalex.org/C127716648","wikidata":"https://www.wikidata.org/wiki/Q104053","display_name":"Phenotype","level":3,"score":0.08466488122940063},{"id":"https://openalex.org/C120665830","wikidata":"https://www.wikidata.org/wiki/Q14620","display_name":"Optics","level":1,"score":0.0},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.0},{"id":"https://openalex.org/C138885662","wikidata":"https://www.wikidata.org/wiki/Q5891","display_name":"Philosophy","level":0,"score":0.0},{"id":"https://openalex.org/C111472728","wikidata":"https://www.wikidata.org/wiki/Q9471","display_name":"Epistemology","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000071841","descriptor_name":"PAX6 Transcription Factor","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000595","descriptor_name":"Amino Acid Sequence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004268","descriptor_name":"DNA-Binding Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D005075","descriptor_name":"Biological Evolution","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005123","descriptor_name":"Eye","qualifier_ui":"Q000254","qualifier_name":"growth & development","is_major_topic":true},{"descriptor_ui":"D005136","descriptor_name":"Eye Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008969","descriptor_name":"Molecular Sequence Data","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012097","descriptor_name":"Repressor Proteins","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017386","descriptor_name":"Sequence Homology, Amino Acid","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018398","descriptor_name":"Homeodomain Proteins","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D051761","descriptor_name":"Paired Box Transcription Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1016/s0168-9525(99)01776-x","doi":"https://doi.org/10.1016/s0168-9525(99)01776-x","is_oa":false,"landing_page_url":"https://doi.org/10.1016/s0168-9525(99)01776-x","pdf_url":null,"source":{"id":"https://openalex.org/S139283865","display_name":"Trends in Genetics","issn_l":"0168-9525","issn":["0168-9525","1362-4555"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Trends in Genetics","raw_type":"journal-article"},{"id":"pmid:10461206","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/10461206","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Trends in genetics : TIG","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":43,"referenced_works":["https://openalex.org/W88989434","https://openalex.org/W1499945097","https://openalex.org/W1587508968","https://openalex.org/W1589588578","https://openalex.org/W1594236032","https://openalex.org/W1836075285","https://openalex.org/W1964761197","https://openalex.org/W1966301994","https://openalex.org/W1978637982","https://openalex.org/W1978650654","https://openalex.org/W1980985436","https://openalex.org/W1981598274","https://openalex.org/W1986382645","https://openalex.org/W1988411966","https://openalex.org/W1997339096","https://openalex.org/W1997733820","https://openalex.org/W1998660634","https://openalex.org/W2007054766","https://openalex.org/W2040518150","https://openalex.org/W2040880169","https://openalex.org/W2042993118","https://openalex.org/W2061529313","https://openalex.org/W2064121506","https://openalex.org/W2065127848","https://openalex.org/W2071575397","https://openalex.org/W2082616165","https://openalex.org/W2084518266","https://openalex.org/W2091622403","https://openalex.org/W2091817414","https://openalex.org/W2102589238","https://openalex.org/W2120213194","https://openalex.org/W2133150554","https://openalex.org/W2139103260","https://openalex.org/W2144267063","https://openalex.org/W2152032402","https://openalex.org/W2154040587","https://openalex.org/W2157062249","https://openalex.org/W2161687343","https://openalex.org/W2163573865","https://openalex.org/W2167249461","https://openalex.org/W2172162107","https://openalex.org/W4323238746","https://openalex.org/W6679685245"],"related_works":["https://openalex.org/W2114713190","https://openalex.org/W1991201077","https://openalex.org/W2060768999","https://openalex.org/W1608783464","https://openalex.org/W1976304560","https://openalex.org/W2126931397","https://openalex.org/W1518792602","https://openalex.org/W2411257172","https://openalex.org/W2388042269","https://openalex.org/W1964784387"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":9},{"year":2025,"cited_by_count":12},{"year":2024,"cited_by_count":9},{"year":2023,"cited_by_count":14},{"year":2022,"cited_by_count":11},{"year":2021,"cited_by_count":24},{"year":2020,"cited_by_count":20},{"year":2019,"cited_by_count":9},{"year":2018,"cited_by_count":13},{"year":2017,"cited_by_count":25},{"year":2016,"cited_by_count":28},{"year":2015,"cited_by_count":36},{"year":2014,"cited_by_count":20},{"year":2013,"cited_by_count":28},{"year":2012,"cited_by_count":30}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2016-06-24T00:00:00"}