{"id":"https://openalex.org/W2126253452","doi":"https://doi.org/10.1128/jvi.00642-07","title":"The Role of WWP1-Gag Interaction and Gag Ubiquitination in Assembly and Release of Human T-Cell Leukemia Virus Type 1","display_name":"The Role of WWP1-Gag Interaction and Gag Ubiquitination in Assembly and Release of Human T-Cell Leukemia Virus Type 1","publication_year":2007,"publication_date":"2007-07-04","ids":{"openalex":"https://openalex.org/W2126253452","doi":"https://doi.org/10.1128/jvi.00642-07","mag":"2126253452","pmid":"https://pubmed.ncbi.nlm.nih.gov/17609263","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/2045422"},"language":"en","primary_location":{"id":"doi:10.1128/jvi.00642-07","doi":"https://doi.org/10.1128/jvi.00642-07","is_oa":false,"landing_page_url":"https://doi.org/10.1128/jvi.00642-07","pdf_url":null,"source":{"id":"https://openalex.org/S96615428","display_name":"Journal of Virology","issn_l":"0022-538X","issn":["0022-538X","1070-6321","1098-5514"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-a","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320263","host_organization_name":"American Society for Microbiology","host_organization_lineage":["https://openalex.org/P4310320263"],"host_organization_lineage_names":["American Society for Microbiology"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Virology","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/2045422","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5082378925","display_name":"Gisela Heidecker","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210140884","display_name":"National Cancer Institute","ror":"https://ror.org/040gcmg81","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210140884"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Gisela Heidecker","raw_affiliation_strings":["HIV Drug Resistance Program, NCI-Frederick","National Cancer Institute-Frederick, Frederick, MD 21702-1201, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"HIV Drug Resistance Program, NCI-Frederick","institution_ids":["https://openalex.org/I4210140884"]},{"raw_affiliation_string":"National Cancer Institute-Frederick, Frederick, MD 21702-1201, USA","institution_ids":["https://openalex.org/I4210140884"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5017281636","display_name":"Patricia A. Lloyd","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Patricia A. Lloyd","raw_affiliation_strings":["Basic Research Program"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Basic Research Program","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5023555872","display_name":"Ferri Soheilian","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I880747138","display_name":"Science Applications International Corporation (United States)","ror":"https://ror.org/00zv91802","country_code":"US","type":"company","lineage":["https://openalex.org/I880747138"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Ferri Soheilian","raw_affiliation_strings":["Image Analysis Laboratory, SAIC-Frederick, Frederick, Maryland 21702"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Image Analysis Laboratory, SAIC-Frederick, Frederick, Maryland 21702","institution_ids":["https://openalex.org/I880747138"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5069268501","display_name":"Kunio Nagashima","orcid":"https://orcid.org/0000-0002-0381-8532","observed_orcids":["https://orcid.org/0000-0002-0381-8532"]},"institutions":[{"id":"https://openalex.org/I880747138","display_name":"Science Applications International Corporation (United States)","ror":"https://ror.org/00zv91802","country_code":"US","type":"company","lineage":["https://openalex.org/I880747138"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Kunio Nagashima","raw_affiliation_strings":["Image Analysis Laboratory, SAIC-Frederick, Frederick, Maryland 21702"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Image Analysis Laboratory, SAIC-Frederick, Frederick, Maryland 21702","institution_ids":["https://openalex.org/I880747138"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5060177702","display_name":"David Derse","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210140884","display_name":"National Cancer Institute","ror":"https://ror.org/040gcmg81","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210140884"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"David Derse","raw_affiliation_strings":["HIV Drug Resistance Program, NCI-Frederick"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"HIV Drug Resistance Program, NCI-Frederick","institution_ids":["https://openalex.org/I4210140884"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":1.608,"has_fulltext":false,"cited_by_count":39,"citation_normalized_percentile":{"value":0.83580794,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":98},"biblio":{"volume":"81","issue":"18","first_page":"9769","last_page":"9777"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12159","display_name":"T-cell and Retrovirus Studies","score":0.9976000189781189,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T12159","display_name":"T-cell and Retrovirus Studies","score":0.9976000189781189,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10112","display_name":"HIV Research and Treatment","score":0.0010000000474974513,"subfield":{"id":"https://openalex.org/subfields/2406","display_name":"Virology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11041","display_name":"Ubiquitin and proteasome pathways","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/htlv-1","display_name":"HTLV-1","score":0.9409999847412109},{"id":"https://openalex.org/keywords/wwp1","display_name":"WWP1","score":0.8970000147819519},{"id":"https://openalex.org/keywords/matrix-domain","display_name":"matrix domain","score":0.6899999976158142},{"id":"https://openalex.org/keywords/e3-ubiquitin-ligase","display_name":"E3 ubiquitin ligase","score":0.8450000286102295},{"id":"https://openalex.org/keywords/hect-domain","display_name":"HECT domain","score":0.7429999709129333},{"id":"https://openalex.org/keywords/virus-assembly","display_name":"viral assembly","score":0.6200000047683716},{"id":"https://openalex.org/keywords/budding","display_name":"budding","score":0.6800000071525574},{"id":"https://openalex.org/keywords/particle-release","display_name":"particle release","score":0.6779999732971191},{"id":"https://openalex.org/keywords/dominant-negative","display_name":"dominant negative effect","score":0.8980000019073486},{"id":"https://openalex.org/keywords/retroviruses","display_name":"retroviruses","score":0.5350000262260437}],"concepts":[{"id":"https://openalex.org/C25602115","wikidata":"https://www.wikidata.org/wiki/Q407111","display_name":"Ubiquitin","level":3,"score":0.8330963850021362},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.7606350183486938},{"id":"https://openalex.org/C143065580","wikidata":"https://www.wikidata.org/wiki/Q3285695","display_name":"Mutant","level":3,"score":0.7061773538589478},{"id":"https://openalex.org/C198410946","wikidata":"https://www.wikidata.org/wiki/Q845312","display_name":"Budding","level":2,"score":0.6076829433441162},{"id":"https://openalex.org/C2779562191","wikidata":"https://www.wikidata.org/wiki/Q673848","display_name":"Murine leukemia virus","level":3,"score":0.5686033964157104},{"id":"https://openalex.org/C153911025","wikidata":"https://www.wikidata.org/wiki/Q7202","display_name":"Molecular biology","level":1,"score":0.5232825875282288},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.4998507499694824},{"id":"https://openalex.org/C501734568","wikidata":"https://www.wikidata.org/wiki/Q42918","display_name":"Mutation","level":3,"score":0.4977555572986603},{"id":"https://openalex.org/C6881719","wikidata":"https://www.wikidata.org/wiki/Q5611048","display_name":"Group-specific antigen","level":3,"score":0.4937361180782318},{"id":"https://openalex.org/C134459356","wikidata":"https://www.wikidata.org/wiki/Q4274835","display_name":"Ubiquitin ligase","level":4,"score":0.4588426351547241},{"id":"https://openalex.org/C2522874641","wikidata":"https://www.wikidata.org/wiki/Q808","display_name":"Virus","level":2,"score":0.43876898288726807},{"id":"https://openalex.org/C2776016237","wikidata":"https://www.wikidata.org/wiki/Q178430","display_name":"Lysine","level":3,"score":0.4308604896068573},{"id":"https://openalex.org/C159047783","wikidata":"https://www.wikidata.org/wiki/Q7215","display_name":"Virology","level":1,"score":0.2872259020805359},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.1982799470424652},{"id":"https://openalex.org/C515207424","wikidata":"https://www.wikidata.org/wiki/Q8066","display_name":"Amino acid","level":2,"score":0.1408902108669281},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.10101407766342163}],"mesh":[{"descriptor_ui":"D006367","descriptor_name":"HeLa Cells","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015368","descriptor_name":"Human T-lymphotropic virus 1","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D015368","descriptor_name":"Human T-lymphotropic virus 1","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D015683","descriptor_name":"Gene Products, gag","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D015683","descriptor_name":"Gene Products, gag","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D017434","descriptor_name":"Protein Structure, Tertiary","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D019065","descriptor_name":"Virus Assembly","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D019943","descriptor_name":"Amino Acid Substitution","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020125","descriptor_name":"Mutation, Missense","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020816","descriptor_name":"Amino Acid Motifs","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D025801","descriptor_name":"Ubiquitin","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D025801","descriptor_name":"Ubiquitin","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D044767","descriptor_name":"Ubiquitin-Protein Ligases","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D044767","descriptor_name":"Ubiquitin-Protein Ligases","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true}],"locations_count":3,"locations":[{"id":"doi:10.1128/jvi.00642-07","doi":"https://doi.org/10.1128/jvi.00642-07","is_oa":false,"landing_page_url":"https://doi.org/10.1128/jvi.00642-07","pdf_url":null,"source":{"id":"https://openalex.org/S96615428","display_name":"Journal of Virology","issn_l":"0022-538X","issn":["0022-538X","1070-6321","1098-5514"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-a","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320263","host_organization_name":"American Society for Microbiology","host_organization_lineage":["https://openalex.org/P4310320263"],"host_organization_lineage_names":["American Society for Microbiology"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Virology","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:2045422","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/2045422","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"J Virol","raw_type":"Text"},{"id":"pmid:17609263","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/17609263","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of virology","raw_type":"Comparative Study"}],"best_oa_location":{"id":"pmh:oai:pubmedcentral.nih.gov:2045422","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/2045422","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"J Virol","raw_type":"Text"},"sustainable_development_goals":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G174812244","display_name":"DCTD Computer Support","funder_award_id":"n01co12400-79-0-22","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G1799052500","display_name":null,"funder_award_id":"N01-CO-012400","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"},{"id":"https://openalex.org/G197234505","display_name":null,"funder_award_id":"N01C012400","funder_id":"https://openalex.org/F4320332505","funder_display_name":"U.S. Public Health Service"}],"funders":[{"id":"https://openalex.org/F4320306085","display_name":"U.S. Department of Health and Human Services","ror":"https://ror.org/033jnv181"},{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320332505","display_name":"U.S. Public Health Service","ror":"https://ror.org/05xf94514"},{"id":"https://openalex.org/F4320337351","display_name":"National Cancer Institute","ror":"https://ror.org/040gcmg81"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":67,"referenced_works":["https://openalex.org/W1497941038","https://openalex.org/W1510428118","https://openalex.org/W1813266103","https://openalex.org/W1869944834","https://openalex.org/W1894623846","https://openalex.org/W1967391569","https://openalex.org/W1971907557","https://openalex.org/W1973572007","https://openalex.org/W1978141733","https://openalex.org/W1981449360","https://openalex.org/W1984587504","https://openalex.org/W1989877174","https://openalex.org/W1989970319","https://openalex.org/W1993573856","https://openalex.org/W1993877052","https://openalex.org/W2001377167","https://openalex.org/W2003979167","https://openalex.org/W2008316672","https://openalex.org/W2010585539","https://openalex.org/W2019987740","https://openalex.org/W2023420720","https://openalex.org/W2023427033","https://openalex.org/W2026055716","https://openalex.org/W2027994034","https://openalex.org/W2030489420","https://openalex.org/W2031235040","https://openalex.org/W2042966315","https://openalex.org/W2046182783","https://openalex.org/W2056775476","https://openalex.org/W2058921751","https://openalex.org/W2059814917","https://openalex.org/W2059841928","https://openalex.org/W2060316418","https://openalex.org/W2060809301","https://openalex.org/W2061195173","https://openalex.org/W2071201507","https://openalex.org/W2076919467","https://openalex.org/W2084470763","https://openalex.org/W2095865730","https://openalex.org/W2096284021","https://openalex.org/W2110035857","https://openalex.org/W2112402645","https://openalex.org/W2115909676","https://openalex.org/W2119620543","https://openalex.org/W2123010569","https://openalex.org/W2123460928","https://openalex.org/W2124738737","https://openalex.org/W2128133737","https://openalex.org/W2128625058","https://openalex.org/W2128745387","https://openalex.org/W2130138387","https://openalex.org/W2130448025","https://openalex.org/W2131601598","https://openalex.org/W2133301780","https://openalex.org/W2135590092","https://openalex.org/W2137578684","https://openalex.org/W2137719559","https://openalex.org/W2146667353","https://openalex.org/W2147343725","https://openalex.org/W2152973548","https://openalex.org/W2157103983","https://openalex.org/W2159011164","https://openalex.org/W2159223336","https://openalex.org/W2159930404","https://openalex.org/W2167157589","https://openalex.org/W4211200857","https://openalex.org/W4249167162"],"related_works":["https://openalex.org/W2137719559","https://openalex.org/W2130138387","https://openalex.org/W2152973548","https://openalex.org/W2001377167","https://openalex.org/W7098232414","https://openalex.org/W2030489420","https://openalex.org/W2159930404","https://openalex.org/W2064143007","https://openalex.org/W2142614240","https://openalex.org/W2131601598"],"abstract_inverted_index":{"The":[0],"PPPY":[1,35],"motif":[2,36],"in":[3,57,80,87,118],"the":[4,23,34,58,68,76,84,96,105,119,125,155,173,183,190],"matrix":[5],"(MA)":[6],"domain":[7,25,72],"of":[8,22,28,33,47,60,64,78,99,121,143,145,185,192,194],"human":[9],"T-cell":[10],"leukemia":[11],"virus":[12],"type":[13],"1":[14],"(HTLV-1)":[15],"Gag":[16,54,135,158,167,176],"associates":[17],"with":[18,148],"WWP1,":[19],"a":[20,61,115,178],"member":[21],"HECT":[24,71],"containing":[26],"family":[27],"E3":[29],"ubiquitin":[30],"ligases.":[31],"Mutation":[32],"arrests":[37],"particle":[38,198],"assembly":[39,129],"at":[40,139],"an":[41],"early":[42],"stage":[43],"and":[44,91,113,159],"abolishes":[45],"ubiquitination":[46,79],"MA.":[48],"Similar":[49],"effects":[50],"are":[51],"seen":[52],"when":[53],"is":[55,161],"expressed":[56],"presence":[59],"truncated":[62],"form":[63],"WWP1":[65,160,195],"that":[66,154,172],"lacks":[67],"catalytically":[69],"active":[70],"(C2WW).":[73],"To":[74],"understand":[75],"role":[77],"budding,":[81],"we":[82,170],"mutated":[83],"four":[85],"lysines":[86],"MA":[88,112],"to":[89,131,196],"arginines":[90],"identified":[92],"lysine":[93],"74":[94],"as":[95],"unique":[97],"site":[98],"ubiquitination.":[100,168],"Virus-like":[101],"particles":[102],"produced":[103],"by":[104],"K74R":[106,126,134],"mutant":[107,175],"did":[108],"not":[109],"contain":[110],"ubiquitinated":[111],"showed":[114],"fourfold":[116],"reduction":[117],"release":[120],"infectious":[122],"particles.":[123],"Furthermore,":[124],"mutation":[127],"rendered":[128],"hypersensitive":[130],"C2WW":[132,146],"inhibition;":[133],"budding":[136,184],"was":[137],"inhibited":[138],"significantly":[140],"lower":[141],"levels":[142],"expression":[144],"compared":[147],"wild-type":[149,186],"Gag.":[150],"This":[151],"finding":[152],"indicates":[153],"interaction":[156],"between":[157],"required":[162],"for":[163],"functions":[164],"other":[165],"than":[166],"Additionally,":[169],"show":[171],"PPPY(-)":[174],"exerts":[177],"strong":[179],"dominant-negative":[180],"effect":[181],"on":[182],"Gag,":[187],"further":[188],"supporting":[189],"importance":[191],"recruitment":[193],"achieve":[197],"assembly.":[199]},"counts_by_year":[{"year":2023,"cited_by_count":2},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":2},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":2},{"year":2017,"cited_by_count":2},{"year":2016,"cited_by_count":1},{"year":2014,"cited_by_count":1},{"year":2013,"cited_by_count":4},{"year":2012,"cited_by_count":3}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}