{"id":"https://openalex.org/W2125586005","doi":"https://doi.org/10.1158/0008-5472.can-09-3909","title":"FoxM1B Regulates NEDD4-1 Expression, Leading to Cellular Transformation and Full Malignant Phenotype in Immortalized Human Astrocytes","display_name":"FoxM1B Regulates NEDD4-1 Expression, Leading to Cellular Transformation and Full Malignant Phenotype in Immortalized Human Astrocytes","publication_year":2010,"publication_date":"2010-03-23","ids":{"openalex":"https://openalex.org/W2125586005","doi":"https://doi.org/10.1158/0008-5472.can-09-3909","mag":"2125586005","pmid":"https://pubmed.ncbi.nlm.nih.gov/20332230","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/2848915"},"language":"en","primary_location":{"id":"doi:10.1158/0008-5472.can-09-3909","doi":"https://doi.org/10.1158/0008-5472.can-09-3909","is_oa":true,"landing_page_url":"https://doi.org/10.1158/0008-5472.can-09-3909","pdf_url":"https://aacrjournals.org/cancerres/article-pdf/70/7/2951/2645056/2951.pdf","source":{"id":"https://openalex.org/S168522863","display_name":"Cancer Research","issn_l":"0008-5472","issn":["0008-5472","1538-7445"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320273","host_organization_name":"American Association for Cancer Research","host_organization_lineage":["https://openalex.org/P4310320273"],"host_organization_lineage_names":["American Association for Cancer Research"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cancer Research","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://aacrjournals.org/cancerres/article-pdf/70/7/2951/2645056/2951.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5035770490","display_name":"Bingbing Dai","orcid":"https://orcid.org/0000-0002-2100-6415","observed_orcids":["https://orcid.org/0000-0002-2100-6415"]},"institutions":[{"id":"https://openalex.org/I1343551460","display_name":"The University of Texas MD Anderson Cancer Center","ror":"https://ror.org/04twxam07","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1343551460"]},{"id":"https://openalex.org/I180670191","display_name":"University of California, San Francisco","ror":"https://ror.org/043mz5j54","country_code":"US","type":"education","lineage":["https://openalex.org/I180670191"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Bingbing Dai","raw_affiliation_strings":["Authors' Affiliations: Departments of 1Neurosurgery, 2Radiation Oncology, 3Pathology, and 4Gastrointestinal Medical Oncology, The University of Texas M.D. Anderson Cancer Center; 5Program in Cancer Biology, The University of Texas Graduate School of Biomedical Sciences at Houston, Houston, Texas; and 6Department of Neurological Surgery, The University of California-San Francisco, San Francisco, California","Department of Neurological Surgery, The University of California-San Francisco, San Francisco, California","Program in Cancer Biology, The University of Texas Graduate School of Biomedical Sciences at Houston, Houston, Texas"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Authors' Affiliations: Departments of 1Neurosurgery, 2Radiation Oncology, 3Pathology, and 4Gastrointestinal Medical Oncology, The University of Texas M.D. Anderson Cancer Center; 5Program in Cancer Biology, The University of Texas Graduate School of Biomedical Sciences at Houston, Houston, Texas; and 6Department of Neurological Surgery, The University of California-San Francisco, San Francisco, California","institution_ids":["https://openalex.org/I1343551460","https://openalex.org/I180670191"]},{"raw_affiliation_string":"Department of Neurological Surgery, The University of California-San Francisco, San Francisco, California","institution_ids":["https://openalex.org/I180670191"]},{"raw_affiliation_string":"Program in Cancer Biology, The University of Texas Graduate School of Biomedical Sciences at Houston, Houston, Texas","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111811939","display_name":"Russell O. Pieper","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1343551460","display_name":"The University of Texas MD Anderson Cancer Center","ror":"https://ror.org/04twxam07","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1343551460"]},{"id":"https://openalex.org/I180670191","display_name":"University of California, San Francisco","ror":"https://ror.org/043mz5j54","country_code":"US","type":"education","lineage":["https://openalex.org/I180670191"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Russell O. Pieper","raw_affiliation_strings":["Authors' Affiliations: Departments of 1Neurosurgery, 2Radiation Oncology, 3Pathology, and 4Gastrointestinal Medical Oncology, The University of Texas M.D. Anderson Cancer Center; 5Program in Cancer Biology, The University of Texas Graduate School of Biomedical Sciences at Houston, Houston, Texas; and 6Department of Neurological Surgery, The University of California-San Francisco, San Francisco, California","Department of Neurological Surgery, The University of California-San Francisco, San Francisco, California","Program in Cancer Biology, The University of Texas Graduate School of Biomedical Sciences at Houston, Houston, Texas"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Authors' Affiliations: Departments of 1Neurosurgery, 2Radiation Oncology, 3Pathology, and 4Gastrointestinal Medical Oncology, The University of Texas M.D. Anderson Cancer Center; 5Program in Cancer Biology, The University of Texas Graduate School of Biomedical Sciences at Houston, Houston, Texas; and 6Department of Neurological Surgery, The University of California-San Francisco, San Francisco, California","institution_ids":["https://openalex.org/I1343551460","https://openalex.org/I180670191"]},{"raw_affiliation_string":"Department of Neurological Surgery, The University of California-San Francisco, San Francisco, California","institution_ids":["https://openalex.org/I180670191"]},{"raw_affiliation_string":"Program in Cancer Biology, The University of Texas Graduate School of Biomedical Sciences at Houston, Houston, Texas","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100324948","display_name":"Dawei Li","orcid":"https://orcid.org/0000-0002-3243-2911","observed_orcids":["https://orcid.org/0000-0002-3243-2911"]},"institutions":[{"id":"https://openalex.org/I1343551460","display_name":"The University of Texas MD Anderson Cancer Center","ror":"https://ror.org/04twxam07","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1343551460"]},{"id":"https://openalex.org/I180670191","display_name":"University of California, San Francisco","ror":"https://ror.org/043mz5j54","country_code":"US","type":"education","lineage":["https://openalex.org/I180670191"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Dawei Li","raw_affiliation_strings":["Authors' Affiliations: Departments of 1Neurosurgery, 2Radiation Oncology, 3Pathology, and 4Gastrointestinal Medical Oncology, The University of Texas M.D. Anderson Cancer Center; 5Program in Cancer Biology, The University of Texas Graduate School of Biomedical Sciences at Houston, Houston, Texas; and 6Department of Neurological Surgery, The University of California-San Francisco, San Francisco, California","Department of Neurological Surgery, The University of California-San Francisco, San Francisco, California","Program in Cancer Biology, The University of Texas Graduate School of Biomedical Sciences at Houston, Houston, Texas"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Authors' Affiliations: Departments of 1Neurosurgery, 2Radiation Oncology, 3Pathology, and 4Gastrointestinal Medical Oncology, The University of Texas M.D. Anderson Cancer Center; 5Program in Cancer Biology, The University of Texas Graduate School of Biomedical Sciences at Houston, Houston, Texas; and 6Department of Neurological Surgery, The University of California-San Francisco, San Francisco, California","institution_ids":["https://openalex.org/I1343551460","https://openalex.org/I180670191"]},{"raw_affiliation_string":"Department of Neurological Surgery, The University of California-San Francisco, San Francisco, California","institution_ids":["https://openalex.org/I180670191"]},{"raw_affiliation_string":"Program in Cancer Biology, The University of Texas Graduate School of Biomedical Sciences at Houston, Houston, Texas","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101555095","display_name":"Ping Wei","orcid":"https://orcid.org/0000-0002-9805-6330","observed_orcids":["https://orcid.org/0000-0002-9805-6330"]},"institutions":[{"id":"https://openalex.org/I1343551460","display_name":"The University of Texas MD Anderson Cancer Center","ror":"https://ror.org/04twxam07","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1343551460"]},{"id":"https://openalex.org/I180670191","display_name":"University of California, San Francisco","ror":"https://ror.org/043mz5j54","country_code":"US","type":"education","lineage":["https://openalex.org/I180670191"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Ping Wei","raw_affiliation_strings":["Authors' Affiliations: Departments of 1Neurosurgery, 2Radiation Oncology, 3Pathology, and 4Gastrointestinal Medical Oncology, The University of Texas M.D. Anderson Cancer Center; 5Program in Cancer Biology, The University of Texas Graduate School of Biomedical Sciences at Houston, Houston, Texas; and 6Department of Neurological Surgery, The University of California-San Francisco, San Francisco, California","Department of Neurological Surgery, The University of California-San Francisco, San Francisco, California","Program in Cancer Biology, The University of Texas Graduate School of Biomedical Sciences at Houston, Houston, Texas"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Authors' Affiliations: Departments of 1Neurosurgery, 2Radiation Oncology, 3Pathology, and 4Gastrointestinal Medical Oncology, The University of Texas M.D. Anderson Cancer Center; 5Program in Cancer Biology, The University of Texas Graduate School of Biomedical Sciences at Houston, Houston, Texas; and 6Department of Neurological Surgery, The University of California-San Francisco, San Francisco, California","institution_ids":["https://openalex.org/I1343551460","https://openalex.org/I180670191"]},{"raw_affiliation_string":"Department of Neurological Surgery, The University of California-San Francisco, San Francisco, California","institution_ids":["https://openalex.org/I180670191"]},{"raw_affiliation_string":"Program in Cancer Biology, The University of Texas Graduate School of Biomedical Sciences at Houston, Houston, Texas","institution_ids":[]}]},{"author_position":"middle","author":{"id":null,"display_name":"Mingguang Liu","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1343551460","display_name":"The University of Texas MD Anderson Cancer Center","ror":"https://ror.org/04twxam07","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1343551460"]},{"id":"https://openalex.org/I180670191","display_name":"University of California, San Francisco","ror":"https://ror.org/043mz5j54","country_code":"US","type":"education","lineage":["https://openalex.org/I180670191"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Mingguang Liu","raw_affiliation_strings":["Authors' Affiliations: Departments of 1Neurosurgery, 2Radiation Oncology, 3Pathology, and 4Gastrointestinal Medical Oncology, The University of Texas M.D. Anderson Cancer Center; 5Program in Cancer Biology, The University of Texas Graduate School of Biomedical Sciences at Houston, Houston, Texas; and 6Department of Neurological Surgery, The University of California-San Francisco, San Francisco, California","Department of Neurological Surgery, The University of California-San Francisco, San Francisco, California","Program in Cancer Biology, The University of Texas Graduate School of Biomedical Sciences at Houston, Houston, Texas"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Authors' Affiliations: Departments of 1Neurosurgery, 2Radiation Oncology, 3Pathology, and 4Gastrointestinal Medical Oncology, The University of Texas M.D. Anderson Cancer Center; 5Program in Cancer Biology, The University of Texas Graduate School of Biomedical Sciences at Houston, Houston, Texas; and 6Department of Neurological Surgery, The University of California-San Francisco, San Francisco, California","institution_ids":["https://openalex.org/I1343551460","https://openalex.org/I180670191"]},{"raw_affiliation_string":"Department of Neurological Surgery, The University of California-San Francisco, San Francisco, California","institution_ids":["https://openalex.org/I180670191"]},{"raw_affiliation_string":"Program in Cancer Biology, The University of Texas Graduate School of Biomedical Sciences at Houston, Houston, Texas","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5027840538","display_name":"Shiao Y. Woo","orcid":"https://orcid.org/0000-0002-2220-1597","observed_orcids":["https://orcid.org/0000-0002-2220-1597"]},"institutions":[{"id":"https://openalex.org/I1343551460","display_name":"The University of Texas MD Anderson Cancer Center","ror":"https://ror.org/04twxam07","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1343551460"]},{"id":"https://openalex.org/I180670191","display_name":"University of California, San Francisco","ror":"https://ror.org/043mz5j54","country_code":"US","type":"education","lineage":["https://openalex.org/I180670191"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Shiao Y. Woo","raw_affiliation_strings":["Authors' Affiliations: Departments of 1Neurosurgery, 2Radiation Oncology, 3Pathology, and 4Gastrointestinal Medical Oncology, The University of Texas M.D. Anderson Cancer Center; 5Program in Cancer Biology, The University of Texas Graduate School of Biomedical Sciences at Houston, Houston, Texas; and 6Department of Neurological Surgery, The University of California-San Francisco, San Francisco, California","Department of Neurological Surgery, The University of California-San Francisco, San Francisco, California","Program in Cancer Biology, The University of Texas Graduate School of Biomedical Sciences at Houston, Houston, Texas"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Authors' Affiliations: Departments of 1Neurosurgery, 2Radiation Oncology, 3Pathology, and 4Gastrointestinal Medical Oncology, The University of Texas M.D. Anderson Cancer Center; 5Program in Cancer Biology, The University of Texas Graduate School of Biomedical Sciences at Houston, Houston, Texas; and 6Department of Neurological Surgery, The University of California-San Francisco, San Francisco, California","institution_ids":["https://openalex.org/I1343551460","https://openalex.org/I180670191"]},{"raw_affiliation_string":"Department of Neurological Surgery, The University of California-San Francisco, San Francisco, California","institution_ids":["https://openalex.org/I180670191"]},{"raw_affiliation_string":"Program in Cancer Biology, The University of Texas Graduate School of Biomedical Sciences at Houston, Houston, Texas","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5063290790","display_name":"Kenneth Aldape","orcid":"https://orcid.org/0000-0001-5119-7550","observed_orcids":["https://orcid.org/0000-0001-5119-7550"]},"institutions":[{"id":"https://openalex.org/I1343551460","display_name":"The University of Texas MD Anderson Cancer Center","ror":"https://ror.org/04twxam07","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1343551460"]},{"id":"https://openalex.org/I180670191","display_name":"University of California, San Francisco","ror":"https://ror.org/043mz5j54","country_code":"US","type":"education","lineage":["https://openalex.org/I180670191"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Kenneth D. Aldape","raw_affiliation_strings":["Authors' Affiliations: Departments of 1Neurosurgery, 2Radiation Oncology, 3Pathology, and 4Gastrointestinal Medical Oncology, The University of Texas M.D. Anderson Cancer Center; 5Program in Cancer Biology, The University of Texas Graduate School of Biomedical Sciences at Houston, Houston, Texas; and 6Department of Neurological Surgery, The University of California-San Francisco, San Francisco, California","Department of Neurological Surgery, The University of California-San Francisco, San Francisco, California"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Authors' Affiliations: Departments of 1Neurosurgery, 2Radiation Oncology, 3Pathology, and 4Gastrointestinal Medical Oncology, The University of Texas M.D. Anderson Cancer Center; 5Program in Cancer Biology, The University of Texas Graduate School of Biomedical Sciences at Houston, Houston, Texas; and 6Department of Neurological Surgery, The University of California-San Francisco, San Francisco, California","institution_ids":["https://openalex.org/I1343551460","https://openalex.org/I180670191"]},{"raw_affiliation_string":"Department of Neurological Surgery, The University of California-San Francisco, San Francisco, California","institution_ids":["https://openalex.org/I180670191"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5091806633","display_name":"Raymond A. Sawaya","orcid":"https://orcid.org/0000-0002-6035-7939","observed_orcids":["https://orcid.org/0000-0002-6035-7939"]},"institutions":[{"id":"https://openalex.org/I1343551460","display_name":"The University of Texas MD Anderson Cancer Center","ror":"https://ror.org/04twxam07","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1343551460"]},{"id":"https://openalex.org/I180670191","display_name":"University of California, San Francisco","ror":"https://ror.org/043mz5j54","country_code":"US","type":"education","lineage":["https://openalex.org/I180670191"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Raymond Sawaya","raw_affiliation_strings":["Authors' Affiliations: Departments of 1Neurosurgery, 2Radiation Oncology, 3Pathology, and 4Gastrointestinal Medical Oncology, The University of Texas M.D. Anderson Cancer Center; 5Program in Cancer Biology, The University of Texas Graduate School of Biomedical Sciences at Houston, Houston, Texas; and 6Department of Neurological Surgery, The University of California-San Francisco, San Francisco, California","Department of Neurological Surgery, The University of California-San Francisco, San Francisco, California","Program in Cancer Biology, The University of Texas Graduate School of Biomedical Sciences at Houston, Houston, Texas"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Authors' Affiliations: Departments of 1Neurosurgery, 2Radiation Oncology, 3Pathology, and 4Gastrointestinal Medical Oncology, The University of Texas M.D. Anderson Cancer Center; 5Program in Cancer Biology, The University of Texas Graduate School of Biomedical Sciences at Houston, Houston, Texas; and 6Department of Neurological Surgery, The University of California-San Francisco, San Francisco, California","institution_ids":["https://openalex.org/I1343551460","https://openalex.org/I180670191"]},{"raw_affiliation_string":"Department of Neurological Surgery, The University of California-San Francisco, San Francisco, California","institution_ids":["https://openalex.org/I180670191"]},{"raw_affiliation_string":"Program in Cancer Biology, The University of Texas Graduate School of Biomedical Sciences at Houston, Houston, Texas","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5059889471","display_name":"Keping Xie","orcid":"https://orcid.org/0000-0001-7887-9586","observed_orcids":["https://orcid.org/0000-0001-7887-9586"]},"institutions":[{"id":"https://openalex.org/I1343551460","display_name":"The University of Texas MD Anderson Cancer Center","ror":"https://ror.org/04twxam07","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1343551460"]},{"id":"https://openalex.org/I180670191","display_name":"University of California, San Francisco","ror":"https://ror.org/043mz5j54","country_code":"US","type":"education","lineage":["https://openalex.org/I180670191"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Keping Xie","raw_affiliation_strings":["Authors' Affiliations: Departments of 1Neurosurgery, 2Radiation Oncology, 3Pathology, and 4Gastrointestinal Medical Oncology, The University of Texas M.D. Anderson Cancer Center; 5Program in Cancer Biology, The University of Texas Graduate School of Biomedical Sciences at Houston, Houston, Texas; and 6Department of Neurological Surgery, The University of California-San Francisco, San Francisco, California","Department of Neurological Surgery, The University of California-San Francisco, San Francisco, California"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Authors' Affiliations: Departments of 1Neurosurgery, 2Radiation Oncology, 3Pathology, and 4Gastrointestinal Medical Oncology, The University of Texas M.D. Anderson Cancer Center; 5Program in Cancer Biology, The University of Texas Graduate School of Biomedical Sciences at Houston, Houston, Texas; and 6Department of Neurological Surgery, The University of California-San Francisco, San Francisco, California","institution_ids":["https://openalex.org/I1343551460","https://openalex.org/I180670191"]},{"raw_affiliation_string":"Department of Neurological Surgery, The University of California-San Francisco, San Francisco, California","institution_ids":["https://openalex.org/I180670191"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5004378997","display_name":"Suyun Huang","orcid":"https://orcid.org/0000-0001-7682-2631","observed_orcids":["https://orcid.org/0000-0001-7682-2631","https://orcid.org/0000-0002-1602-2832"]},"institutions":[{"id":"https://openalex.org/I1343551460","display_name":"The University of Texas MD Anderson Cancer Center","ror":"https://ror.org/04twxam07","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1343551460"]},{"id":"https://openalex.org/I180670191","display_name":"University of California, San Francisco","ror":"https://ror.org/043mz5j54","country_code":"US","type":"education","lineage":["https://openalex.org/I180670191"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Suyun Huang","raw_affiliation_strings":["Authors' Affiliations: Departments of 1Neurosurgery, 2Radiation Oncology, 3Pathology, and 4Gastrointestinal Medical Oncology, The University of Texas M.D. Anderson Cancer Center; 5Program in Cancer Biology, The University of Texas Graduate School of Biomedical Sciences at Houston, Houston, Texas; and 6Department of Neurological Surgery, The University of California-San Francisco, San Francisco, California","Department of Neurological Surgery, The University of California-San Francisco, San Francisco, California"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Authors' Affiliations: Departments of 1Neurosurgery, 2Radiation Oncology, 3Pathology, and 4Gastrointestinal Medical Oncology, The University of Texas M.D. Anderson Cancer Center; 5Program in Cancer Biology, The University of Texas Graduate School of Biomedical Sciences at Houston, Houston, Texas; and 6Department of Neurological Surgery, The University of California-San Francisco, San Francisco, California","institution_ids":["https://openalex.org/I1343551460","https://openalex.org/I180670191"]},{"raw_affiliation_string":"Department of Neurological Surgery, The University of California-San Francisco, San Francisco, California","institution_ids":["https://openalex.org/I180670191"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5004378997"],"corresponding_institution_ids":["https://openalex.org/I1343551460","https://openalex.org/I180670191"],"apc_list":null,"apc_paid":null,"fwci":2.4401,"has_fulltext":true,"cited_by_count":80,"citation_normalized_percentile":{"value":0.88465048,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":99},"biblio":{"volume":"70","issue":"7","first_page":"2951","last_page":"2961"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10129","display_name":"Glioma Diagnosis and Treatment","score":0.9092000126838684,"subfield":{"id":"https://openalex.org/subfields/2716","display_name":"Genetics (clinical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10129","display_name":"Glioma Diagnosis and Treatment","score":0.9092000126838684,"subfield":{"id":"https://openalex.org/subfields/2716","display_name":"Genetics (clinical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12835","display_name":"FOXO transcription factor regulation","score":0.08290000259876251,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T13779","display_name":"Cancer Mechanisms and Therapy","score":0.0015999999595806003,"subfield":{"id":"https://openalex.org/subfields/2734","display_name":"Pathology and Forensic Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/foxm1b","display_name":"FoxM1B","score":0.9990000128746033},{"id":"https://openalex.org/keywords/nedd4-1","display_name":"NEDD4-1","score":0.9980000257492065},{"id":"https://openalex.org/keywords/glioma","display_name":"glioma","score":0.6029999852180481},{"id":"https://openalex.org/keywords/glioblastoma","display_name":"glioblastoma","score":0.9160000085830688},{"id":"https://openalex.org/keywords/astrocyte-transformation","display_name":"astrocyte transformation","score":0.9570000171661377},{"id":"https://openalex.org/keywords/pten-degradation","display_name":"PTEN degradation","score":0.8339999914169312},{"id":"https://openalex.org/keywords/akt-signaling","display_name":"Akt signaling","score":0.9160000085830688},{"id":"https://openalex.org/keywords/foxo3","display_name":"FOXO3","score":0.9599999785423279},{"id":"https://openalex.org/keywords/p53","display_name":"p53","score":0.5849999785423279},{"id":"https://openalex.org/keywords/retinoblastoma-protein","display_name":"retinoblastoma protein","score":0.8799999952316284},{"id":"https://openalex.org/keywords/e3-ubiquitin-ligase","display_name":"E3 ubiquitin ligase","score":0.8259999752044678},{"id":"https://openalex.org/keywords/survivin","display_name":"survivin","score":0.6460000276565552},{"id":"https://openalex.org/keywords/cyclin-d1","display_name":"cyclin D1","score":0.9810000061988831},{"id":"https://openalex.org/keywords/cyclin-e","display_name":"cyclin E","score":0.9869999885559082},{"id":"https://openalex.org/keywords/pi3k-akt-inhibitors","display_name":"PI3K/AKT inhibitors","score":0.7319999933242798}],"concepts":[{"id":"https://openalex.org/C2777609662","wikidata":"https://www.wikidata.org/wiki/Q416356","display_name":"PTEN","level":4,"score":0.8290281295776367},{"id":"https://openalex.org/C75217442","wikidata":"https://www.wikidata.org/wiki/Q423650","display_name":"Protein kinase B","level":3,"score":0.6244426965713501},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.6042778491973877},{"id":"https://openalex.org/C2779549131","wikidata":"https://www.wikidata.org/wiki/Q83167294","display_name":"Tensin","level":5,"score":0.5744472146034241},{"id":"https://openalex.org/C127561419","wikidata":"https://www.wikidata.org/wiki/Q224527","display_name":"Downregulation and upregulation","level":3,"score":0.5594841837882996},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.5513857007026672},{"id":"https://openalex.org/C199835354","wikidata":"https://www.wikidata.org/wiki/Q15311861","display_name":"Cyclin D1","level":4,"score":0.5486505627632141},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.4369608163833618},{"id":"https://openalex.org/C2778227246","wikidata":"https://www.wikidata.org/wiki/Q1365309","display_name":"Glioma","level":2,"score":0.42011559009552},{"id":"https://openalex.org/C31033888","wikidata":"https://www.wikidata.org/wiki/Q752076","display_name":"Malignant transformation","level":2,"score":0.4102550446987152},{"id":"https://openalex.org/C86554907","wikidata":"https://www.wikidata.org/wiki/Q285613","display_name":"PI3K/AKT/mTOR pathway","level":3,"score":0.36071115732192993},{"id":"https://openalex.org/C11960822","wikidata":"https://www.wikidata.org/wiki/Q242736","display_name":"Phosphorylation","level":2,"score":0.33811086416244507},{"id":"https://openalex.org/C62478195","wikidata":"https://www.wikidata.org/wiki/Q828130","display_name":"Signal transduction","level":2,"score":0.3175399601459503},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.31635379791259766},{"id":"https://openalex.org/C29537977","wikidata":"https://www.wikidata.org/wiki/Q188941","display_name":"Cell cycle","level":3,"score":0.23733490705490112},{"id":"https://openalex.org/C1491633281","wikidata":"https://www.wikidata.org/wiki/Q7868","display_name":"Cell","level":2,"score":0.16570040583610535},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.09420782327651978},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000072278","descriptor_name":"Forkhead Box Protein M1","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000075702","descriptor_name":"Nedd4 Ubiquitin Protein Ligases","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000077022","descriptor_name":"Survivin","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001253","descriptor_name":"Astrocytes","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D001253","descriptor_name":"Astrocytes","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D001932","descriptor_name":"Brain Neoplasms","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D001932","descriptor_name":"Brain Neoplasms","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D001932","descriptor_name":"Brain Neoplasms","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D002471","descriptor_name":"Cell Transformation, Neoplastic","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D002471","descriptor_name":"Cell Transformation, Neoplastic","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D004789","descriptor_name":"Enzyme Activation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005910","descriptor_name":"Glioma","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D005910","descriptor_name":"Glioma","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D005910","descriptor_name":"Glioma","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008819","descriptor_name":"Mice, Nude","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008869","descriptor_name":"Microtubule-Associated Proteins","qualifier_ui":"Q000096","qualifier_name":"biosynthesis","is_major_topic":false},{"descriptor_ui":"D008869","descriptor_name":"Microtubule-Associated Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D010641","descriptor_name":"Phenotype","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019927","descriptor_name":"Cyclin E","qualifier_ui":"Q000096","qualifier_name":"biosynthesis","is_major_topic":false},{"descriptor_ui":"D019927","descriptor_name":"Cyclin E","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D019938","descriptor_name":"Cyclin D1","qualifier_ui":"Q000096","qualifier_name":"biosynthesis","is_major_topic":false},{"descriptor_ui":"D019938","descriptor_name":"Cyclin D1","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D044767","descriptor_name":"Ubiquitin-Protein Ligases","qualifier_ui":"Q000096","qualifier_name":"biosynthesis","is_major_topic":true},{"descriptor_ui":"D044767","descriptor_name":"Ubiquitin-Protein Ligases","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D045744","descriptor_name":"Cell Line, Tumor","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051034","descriptor_name":"Inhibitor of Apoptosis Proteins","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051058","descriptor_name":"Oncogene Protein v-akt","qualifier_ui":"Q000037","qualifier_name":"antagonists & inhibitors","is_major_topic":false},{"descriptor_ui":"D051058","descriptor_name":"Oncogene Protein v-akt","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D051059","descriptor_name":"PTEN Phosphohydrolase","qualifier_ui":"Q000096","qualifier_name":"biosynthesis","is_major_topic":false},{"descriptor_ui":"D051059","descriptor_name":"PTEN Phosphohydrolase","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051858","descriptor_name":"Forkhead Transcription Factors","qualifier_ui":"Q000037","qualifier_name":"antagonists & inhibitors","is_major_topic":false},{"descriptor_ui":"D051858","descriptor_name":"Forkhead Transcription Factors","qualifier_ui":"Q000096","qualifier_name":"biosynthesis","is_major_topic":true},{"descriptor_ui":"D051858","descriptor_name":"Forkhead Transcription Factors","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D056827","descriptor_name":"Endosomal Sorting Complexes Required for Transport","qualifier_ui":"Q000096","qualifier_name":"biosynthesis","is_major_topic":true},{"descriptor_ui":"D056827","descriptor_name":"Endosomal Sorting Complexes Required for Transport","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false}],"locations_count":5,"locations":[{"id":"doi:10.1158/0008-5472.can-09-3909","doi":"https://doi.org/10.1158/0008-5472.can-09-3909","is_oa":true,"landing_page_url":"https://doi.org/10.1158/0008-5472.can-09-3909","pdf_url":"https://aacrjournals.org/cancerres/article-pdf/70/7/2951/2645056/2951.pdf","source":{"id":"https://openalex.org/S168522863","display_name":"Cancer Research","issn_l":"0008-5472","issn":["0008-5472","1538-7445"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320273","host_organization_name":"American Association for Cancer Research","host_organization_lineage":["https://openalex.org/P4310320273"],"host_organization_lineage_names":["American Association for Cancer Research"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cancer Research","raw_type":"journal-article"},{"id":"pmid:20332230","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/20332230","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cancer research","raw_type":"Journal Article"},{"id":"pmh:oai:europepmc.org:2077528","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/2848915","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":null,"raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:2848915","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/2848915","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"Cancer Res","raw_type":"Text"},{"id":"pmh:oai:digitalcommons.library.tmc.edu:uthgsbs_docs-1025","doi":null,"is_oa":false,"landing_page_url":"https://digitalcommons.library.tmc.edu/uthgsbs_docs/43","pdf_url":null,"source":{"id":"https://openalex.org/S4377196655","display_name":"Digital Commons-TMC (Texas Medical Center)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1337852284","host_organization_name":"Texas Medical Center","host_organization_lineage":["https://openalex.org/I1337852284"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Faculty, Staff and Student Publications","raw_type":"text"}],"best_oa_location":{"id":"doi:10.1158/0008-5472.can-09-3909","doi":"https://doi.org/10.1158/0008-5472.can-09-3909","is_oa":true,"landing_page_url":"https://doi.org/10.1158/0008-5472.can-09-3909","pdf_url":"https://aacrjournals.org/cancerres/article-pdf/70/7/2951/2645056/2951.pdf","source":{"id":"https://openalex.org/S168522863","display_name":"Cancer Research","issn_l":"0008-5472","issn":["0008-5472","1538-7445"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320273","host_organization_name":"American Association for Cancer Research","host_organization_lineage":["https://openalex.org/P4310320273"],"host_organization_lineage_names":["American Association for Cancer Research"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cancer Research","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.9391000270843506,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G8709120508","display_name":"The Fox M1 in Human Glioma Development and Progression","funder_award_id":"R01CA116528","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"},{"id":"https://openalex.org/G9000904906","display_name":"SPORE in Brain Cancer","funder_award_id":"P50CA127001","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"}],"funders":[{"id":"https://openalex.org/F4320337351","display_name":"National Cancer Institute","ror":"https://ror.org/040gcmg81"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2125586005.pdf","grobid_xml":"https://content.openalex.org/works/W2125586005.grobid-xml"},"referenced_works_count":52,"referenced_works":["https://openalex.org/W199447113","https://openalex.org/W1562223973","https://openalex.org/W1576656296","https://openalex.org/W1611336610","https://openalex.org/W1655331233","https://openalex.org/W1979177187","https://openalex.org/W1985921109","https://openalex.org/W1987090100","https://openalex.org/W1987986416","https://openalex.org/W1988769784","https://openalex.org/W1990788833","https://openalex.org/W1998038367","https://openalex.org/W1998771818","https://openalex.org/W2000926872","https://openalex.org/W2010677999","https://openalex.org/W2019017173","https://openalex.org/W2025183726","https://openalex.org/W2030083720","https://openalex.org/W2030380217","https://openalex.org/W2042889829","https://openalex.org/W2044078154","https://openalex.org/W2052588647","https://openalex.org/W2062104023","https://openalex.org/W2064475051","https://openalex.org/W2068261932","https://openalex.org/W2068427129","https://openalex.org/W2073567125","https://openalex.org/W2080664885","https://openalex.org/W2099658407","https://openalex.org/W2100553819","https://openalex.org/W2103612830","https://openalex.org/W2105005481","https://openalex.org/W2109610561","https://openalex.org/W2112785522","https://openalex.org/W2114811646","https://openalex.org/W2114998237","https://openalex.org/W2120026837","https://openalex.org/W2126141743","https://openalex.org/W2138897067","https://openalex.org/W2143004704","https://openalex.org/W2144540644","https://openalex.org/W2154575661","https://openalex.org/W2156122059","https://openalex.org/W2156216950","https://openalex.org/W2158838322","https://openalex.org/W2163325084","https://openalex.org/W2169300384","https://openalex.org/W2171293990","https://openalex.org/W2320297010","https://openalex.org/W2391415472","https://openalex.org/W6675488394","https://openalex.org/W6678779827"],"related_works":["https://openalex.org/W2239600220","https://openalex.org/W2138897067","https://openalex.org/W1985921109","https://openalex.org/W2140520689","https://openalex.org/W2799683421","https://openalex.org/W2326315055","https://openalex.org/W2744057663","https://openalex.org/W3159629544","https://openalex.org/W2055134485","https://openalex.org/W2035618592"],"abstract_inverted_index":{"Our":[0],"recent":[1],"studies":[2],"have":[3],"shown":[4],"that":[5,17,50,74,89,110,119,196],"the":[6,18,35,51,98,121,141,162,176],"FoxM1B":[7,30,52,90,113,171],"transcription":[8],"factor":[9],"is":[10,43],"overexpressed":[11],"in":[12,34,41,60,92,131,137,140,172,200,207],"human":[13,62],"glioma":[14,26,39],"tissues":[15],"and":[16,57,68,123,127,149,182,204,213],"level":[19],"of":[20,38,79,112,125,143,152,165,170,178,198],"its":[21],"expression":[22,177],"correlates":[23],"directly":[24],"with":[25,157,202],"grade.":[27],"However,":[28],"whether":[29],"plays":[31],"a":[32],"role":[33],"early":[36],"development":[37],"(i.e.,":[40],"transformation)":[42],"unknown.":[44],"In":[45],"this":[46],"study,":[47],"we":[48],"found":[49],"molecule":[53],"causes":[54],"cellular":[55],"transformation":[56,164,212],"tumor":[58,190],"formation":[59,215],"normal":[61],"astrocytes":[63],"(NHA)":[64],"immortalized":[65,81,93,166,173],"by":[66],"p53":[67,203],"pRB":[69,205],"inhibition.":[70],"Moreover,":[71],"brain":[72],"tumors":[73],"arose":[75],"from":[76],"intracranial":[77],"injection":[78],"FoxM1B-expressing":[80],"NHAs":[82,94,174],"displayed":[83],"glioblastoma":[84],"multiforme":[85],"(GBM)":[86],"phenotypes,":[87],"suggesting":[88],"overexpression":[91,111,169,197],"not":[95],"only":[96],"transforms":[97],"cells":[99],"but":[100],"also":[101],"leads":[102],"to":[103,147],"GBM":[104,214],"formation.":[105],"Mechanistically,":[106],"our":[107],"results":[108,194],"showed":[109],"upregulated":[114],"NEDD4-1,":[115],"an":[116],"E3":[117],"ligase":[118],"mediates":[120],"degradation":[122],"downregulation":[124],"phosphatase":[126],"tensin":[128],"homologue":[129],"(PTEN)":[130],"multiple":[132,217],"cell":[133],"lines.":[134],"Decreased":[135],"PTEN":[136],"turn":[138],"resulted":[139],"hyperactivation":[142],"Akt,":[144],"which":[145,185],"led":[146],"phosphorylation":[148],"cytoplasmic":[150],"retention":[151],"FoxO3a.":[153],"Blocking":[154],"Akt":[155],"activation":[156],"phosphoinositide":[158],"3-kinase/Akt":[159],"inhibitors":[160],"inhibited":[161],"FoxM1B-induced":[163],"NHAs.":[167],"Furthermore,":[168],"increased":[175],"survivin,":[179],"cyclin":[180,183],"D1,":[181],"E,":[184],"are":[186],"important":[187],"molecules":[188],"for":[189],"growth.":[191],"Collectively,":[192],"these":[193],"indicate":[195],"FoxM1B,":[199],"cooperation":[201],"inhibition":[206],"NHA":[208],"cells,":[209],"promotes":[210],"astrocyte":[211],"through":[216],"mechanisms.":[218]},"counts_by_year":[{"year":2026,"cited_by_count":3},{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":4},{"year":2022,"cited_by_count":4},{"year":2021,"cited_by_count":7},{"year":2020,"cited_by_count":9},{"year":2019,"cited_by_count":4},{"year":2018,"cited_by_count":5},{"year":2017,"cited_by_count":7},{"year":2016,"cited_by_count":3},{"year":2015,"cited_by_count":5},{"year":2014,"cited_by_count":8},{"year":2013,"cited_by_count":8},{"year":2012,"cited_by_count":6}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}