{"id":"https://openalex.org/W2125196387","doi":"https://doi.org/10.1158/1940-6207.capr-10-0389","title":"Hormonal Factors and Risks of Esophageal Squamous Cell Carcinoma and Adenocarcinoma in Postmenopausal Women","display_name":"Hormonal Factors and Risks of Esophageal Squamous Cell Carcinoma and Adenocarcinoma in Postmenopausal Women","publication_year":2011,"publication_date":"2011-04-20","ids":{"openalex":"https://openalex.org/W2125196387","doi":"https://doi.org/10.1158/1940-6207.capr-10-0389","mag":"2125196387","pmid":"https://pubmed.ncbi.nlm.nih.gov/21505180","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/3107894"},"language":"en","primary_location":{"id":"doi:10.1158/1940-6207.capr-10-0389","doi":"https://doi.org/10.1158/1940-6207.capr-10-0389","is_oa":false,"landing_page_url":"https://doi.org/10.1158/1940-6207.capr-10-0389","pdf_url":null,"source":{"id":"https://openalex.org/S68240649","display_name":"Cancer Prevention Research","issn_l":"1940-6207","issn":["1940-6207","1940-6215"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320273","host_organization_name":"American Association for Cancer Research","host_organization_lineage":["https://openalex.org/P4310320273"],"host_organization_lineage_names":["American Association for Cancer Research"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cancer Prevention Research","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3107894","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5035590648","display_name":"Clara Bodel\u00f3n","orcid":"https://orcid.org/0000-0002-6578-2678","observed_orcids":["https://orcid.org/0000-0002-6578-2678"]},"institutions":[{"id":"https://openalex.org/I177607063","display_name":"The Lundquist Institute","ror":"https://ror.org/025j2nd68","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I177607063"]},{"id":"https://openalex.org/I201448701","display_name":"University of Washington","ror":"https://ror.org/00cvxb145","country_code":"US","type":"education","lineage":["https://openalex.org/I201448701"]},{"id":"https://openalex.org/I4210089486","display_name":"Fred Hutch Cancer Center","ror":"https://ror.org/007ps6h72","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I4210089486"]},{"id":"https://openalex.org/I4210165985","display_name":"Harbor\u2013UCLA Medical Center","ror":"https://ror.org/05h4zj272","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1328359107","https://openalex.org/I4210165985"]},{"id":"https://openalex.org/I63190737","display_name":"University at Buffalo, State University of New York","ror":"https://ror.org/01y64my43","country_code":"US","type":"education","lineage":["https://openalex.org/I63190737"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Clara Bodelon","raw_affiliation_strings":["Authors' Affiliations:\u20081Department of Epidemiology, School of Public Health, University of Washington, 2Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington; 3Department of Medicine, Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center, Torrance, California; and 4Department of Social and Preventive Medicine, School of Public Health and Health Professions, University at Buffalo, Buffalo, New York"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Authors' Affiliations:\u20081Department of Epidemiology, School of Public Health, University of Washington, 2Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington; 3Department of Medicine, Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center, Torrance, California; and 4Department of Social and Preventive Medicine, School of Public Health and Health Professions, University at Buffalo, Buffalo, New York","institution_ids":["https://openalex.org/I177607063","https://openalex.org/I201448701","https://openalex.org/I4210089486","https://openalex.org/I4210165985","https://openalex.org/I63190737"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5043491217","display_name":"Garnet L. Anderson","orcid":"https://orcid.org/0000-0001-5087-7837","observed_orcids":["https://orcid.org/0000-0001-5087-7837"]},"institutions":[{"id":"https://openalex.org/I177607063","display_name":"The Lundquist Institute","ror":"https://ror.org/025j2nd68","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I177607063"]},{"id":"https://openalex.org/I201448701","display_name":"University of Washington","ror":"https://ror.org/00cvxb145","country_code":"US","type":"education","lineage":["https://openalex.org/I201448701"]},{"id":"https://openalex.org/I4210089486","display_name":"Fred Hutch Cancer Center","ror":"https://ror.org/007ps6h72","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I4210089486"]},{"id":"https://openalex.org/I4210165985","display_name":"Harbor\u2013UCLA Medical Center","ror":"https://ror.org/05h4zj272","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1328359107","https://openalex.org/I4210165985"]},{"id":"https://openalex.org/I63190737","display_name":"University at Buffalo, State University of New York","ror":"https://ror.org/01y64my43","country_code":"US","type":"education","lineage":["https://openalex.org/I63190737"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Garnet L. Anderson","raw_affiliation_strings":["Authors' Affiliations:\u20081Department of Epidemiology, School of Public Health, University of Washington, 2Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington; 3Department of Medicine, Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center, Torrance, California; and 4Department of Social and Preventive Medicine, School of Public Health and Health Professions, University at Buffalo, Buffalo, New York","Department of Social and Preventive Medicine, School of Public Health and Health Professions, University at Buffalo, Buffalo, New York"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Authors' Affiliations:\u20081Department of Epidemiology, School of Public Health, University of Washington, 2Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington; 3Department of Medicine, Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center, Torrance, California; and 4Department of Social and Preventive Medicine, School of Public Health and Health Professions, University at Buffalo, Buffalo, New York","institution_ids":["https://openalex.org/I177607063","https://openalex.org/I201448701","https://openalex.org/I4210089486","https://openalex.org/I4210165985","https://openalex.org/I63190737"]},{"raw_affiliation_string":"Department of Social and Preventive Medicine, School of Public Health and Health Professions, University at Buffalo, Buffalo, New York","institution_ids":["https://openalex.org/I63190737"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5107857650","display_name":"Mary Anne Rossing","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I177607063","display_name":"The Lundquist Institute","ror":"https://ror.org/025j2nd68","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I177607063"]},{"id":"https://openalex.org/I201448701","display_name":"University of Washington","ror":"https://ror.org/00cvxb145","country_code":"US","type":"education","lineage":["https://openalex.org/I201448701"]},{"id":"https://openalex.org/I4210089486","display_name":"Fred Hutch Cancer Center","ror":"https://ror.org/007ps6h72","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I4210089486"]},{"id":"https://openalex.org/I4210165985","display_name":"Harbor\u2013UCLA Medical Center","ror":"https://ror.org/05h4zj272","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1328359107","https://openalex.org/I4210165985"]},{"id":"https://openalex.org/I63190737","display_name":"University at Buffalo, State University of New York","ror":"https://ror.org/01y64my43","country_code":"US","type":"education","lineage":["https://openalex.org/I63190737"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Mary Anne Rossing","raw_affiliation_strings":["Authors' Affiliations:\u20081Department of Epidemiology, School of Public Health, University of Washington, 2Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington; 3Department of Medicine, Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center, Torrance, California; and 4Department of Social and Preventive Medicine, School of Public Health and Health Professions, University at Buffalo, Buffalo, New York"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Authors' Affiliations:\u20081Department of Epidemiology, School of Public Health, University of Washington, 2Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington; 3Department of Medicine, Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center, Torrance, California; and 4Department of Social and Preventive Medicine, School of Public Health and Health Professions, University at Buffalo, Buffalo, New York","institution_ids":["https://openalex.org/I177607063","https://openalex.org/I201448701","https://openalex.org/I4210089486","https://openalex.org/I4210165985","https://openalex.org/I63190737"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5004840750","display_name":"Rowan T. Chlebowski","orcid":"https://orcid.org/0000-0002-4212-6184","observed_orcids":["https://orcid.org/0000-0002-4212-6184"]},"institutions":[{"id":"https://openalex.org/I177607063","display_name":"The Lundquist Institute","ror":"https://ror.org/025j2nd68","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I177607063"]},{"id":"https://openalex.org/I201448701","display_name":"University of Washington","ror":"https://ror.org/00cvxb145","country_code":"US","type":"education","lineage":["https://openalex.org/I201448701"]},{"id":"https://openalex.org/I4210089486","display_name":"Fred Hutch Cancer Center","ror":"https://ror.org/007ps6h72","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I4210089486"]},{"id":"https://openalex.org/I4210165985","display_name":"Harbor\u2013UCLA Medical Center","ror":"https://ror.org/05h4zj272","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1328359107","https://openalex.org/I4210165985"]},{"id":"https://openalex.org/I63190737","display_name":"University at Buffalo, State University of New York","ror":"https://ror.org/01y64my43","country_code":"US","type":"education","lineage":["https://openalex.org/I63190737"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Rowan T. Chlebowski","raw_affiliation_strings":["Authors' Affiliations:\u20081Department of Epidemiology, School of Public Health, University of Washington, 2Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington; 3Department of Medicine, Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center, Torrance, California; and 4Department of Social and Preventive Medicine, School of Public Health and Health Professions, University at Buffalo, Buffalo, New York","Department of Social and Preventive Medicine, School of Public Health and Health Professions, University at Buffalo, Buffalo, New York"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Authors' Affiliations:\u20081Department of Epidemiology, School of Public Health, University of Washington, 2Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington; 3Department of Medicine, Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center, Torrance, California; and 4Department of Social and Preventive Medicine, School of Public Health and Health Professions, University at Buffalo, Buffalo, New York","institution_ids":["https://openalex.org/I177607063","https://openalex.org/I201448701","https://openalex.org/I4210089486","https://openalex.org/I4210165985","https://openalex.org/I63190737"]},{"raw_affiliation_string":"Department of Social and Preventive Medicine, School of Public Health and Health Professions, University at Buffalo, Buffalo, New York","institution_ids":["https://openalex.org/I63190737"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5018608949","display_name":"Heather M. Ochs\u2010Balcom","orcid":"https://orcid.org/0000-0003-1255-7714","observed_orcids":["https://orcid.org/0000-0003-1255-7714"]},"institutions":[{"id":"https://openalex.org/I177607063","display_name":"The Lundquist Institute","ror":"https://ror.org/025j2nd68","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I177607063"]},{"id":"https://openalex.org/I201448701","display_name":"University of Washington","ror":"https://ror.org/00cvxb145","country_code":"US","type":"education","lineage":["https://openalex.org/I201448701"]},{"id":"https://openalex.org/I4210089486","display_name":"Fred Hutch Cancer Center","ror":"https://ror.org/007ps6h72","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I4210089486"]},{"id":"https://openalex.org/I4210165985","display_name":"Harbor\u2013UCLA Medical Center","ror":"https://ror.org/05h4zj272","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1328359107","https://openalex.org/I4210165985"]},{"id":"https://openalex.org/I63190737","display_name":"University at Buffalo, State University of New York","ror":"https://ror.org/01y64my43","country_code":"US","type":"education","lineage":["https://openalex.org/I63190737"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Heather M. Ochs-Balcom","raw_affiliation_strings":["Authors' Affiliations:\u20081Department of Epidemiology, School of Public Health, University of Washington, 2Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington; 3Department of Medicine, Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center, Torrance, California; and 4Department of Social and Preventive Medicine, School of Public Health and Health Professions, University at Buffalo, Buffalo, New York","Department of Social and Preventive Medicine, School of Public Health and Health Professions, University at Buffalo, Buffalo, New York"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Authors' Affiliations:\u20081Department of Epidemiology, School of Public Health, University of Washington, 2Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington; 3Department of Medicine, Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center, Torrance, California; and 4Department of Social and Preventive Medicine, School of Public Health and Health Professions, University at Buffalo, Buffalo, New York","institution_ids":["https://openalex.org/I177607063","https://openalex.org/I201448701","https://openalex.org/I4210089486","https://openalex.org/I4210165985","https://openalex.org/I63190737"]},{"raw_affiliation_string":"Department of Social and Preventive Medicine, School of Public Health and Health Professions, University at Buffalo, Buffalo, New York","institution_ids":["https://openalex.org/I63190737"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5011306393","display_name":"Thomas L. Vaughan","orcid":"https://orcid.org/0000-0003-1537-0242","observed_orcids":["https://orcid.org/0000-0003-1537-0242"]},"institutions":[{"id":"https://openalex.org/I177607063","display_name":"The Lundquist Institute","ror":"https://ror.org/025j2nd68","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I177607063"]},{"id":"https://openalex.org/I201448701","display_name":"University of Washington","ror":"https://ror.org/00cvxb145","country_code":"US","type":"education","lineage":["https://openalex.org/I201448701"]},{"id":"https://openalex.org/I4210089486","display_name":"Fred Hutch Cancer Center","ror":"https://ror.org/007ps6h72","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I4210089486"]},{"id":"https://openalex.org/I4210165985","display_name":"Harbor\u2013UCLA Medical Center","ror":"https://ror.org/05h4zj272","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1328359107","https://openalex.org/I4210165985"]},{"id":"https://openalex.org/I63190737","display_name":"University at Buffalo, State University of New York","ror":"https://ror.org/01y64my43","country_code":"US","type":"education","lineage":["https://openalex.org/I63190737"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Thomas L. Vaughan","raw_affiliation_strings":["Authors' Affiliations:\u20081Department of Epidemiology, School of Public Health, University of Washington, 2Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington; 3Department of Medicine, Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center, Torrance, California; and 4Department of Social and Preventive Medicine, School of Public Health and Health Professions, University at Buffalo, Buffalo, New York"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Authors' Affiliations:\u20081Department of Epidemiology, School of Public Health, University of Washington, 2Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington; 3Department of Medicine, Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center, Torrance, California; and 4Department of Social and Preventive Medicine, School of Public Health and Health Professions, University at Buffalo, Buffalo, New York","institution_ids":["https://openalex.org/I177607063","https://openalex.org/I201448701","https://openalex.org/I4210089486","https://openalex.org/I4210165985","https://openalex.org/I63190737"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":5,"corresponding_author_ids":["https://openalex.org/A5035590648"],"corresponding_institution_ids":["https://openalex.org/I177607063","https://openalex.org/I201448701","https://openalex.org/I4210089486","https://openalex.org/I4210165985","https://openalex.org/I63190737"],"apc_list":null,"apc_paid":null,"fwci":4.2502,"has_fulltext":false,"cited_by_count":60,"citation_normalized_percentile":{"value":0.93940362,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":89,"max":99},"biblio":{"volume":"4","issue":"6","first_page":"840","last_page":"850"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10619","display_name":"Esophageal Cancer Research and Treatment","score":0.9833999872207642,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10619","display_name":"Esophageal Cancer Research and Treatment","score":0.9833999872207642,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10694","display_name":"Menopause: Health Impacts and Treatments","score":0.01360000018030405,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10307","display_name":"Head and Neck Cancer Studies","score":0.0007999999797903001,"subfield":{"id":"https://openalex.org/subfields/2733","display_name":"Otorhinolaryngology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/esophageal-squamous-cell-carcinoma","display_name":"esophageal squamous cell carcinoma","score":0.9549999833106995},{"id":"https://openalex.org/keywords/esophageal-adenocarcinoma","display_name":"esophageal adenocarcinoma","score":1.0},{"id":"https://openalex.org/keywords/hormone-therapy","display_name":"hormone therapy","score":0.8610000014305115},{"id":"https://openalex.org/keywords/postmenopausal-women","display_name":"postmenopausal women","score":0.8820000290870667},{"id":"https://openalex.org/keywords/estrogen-plus-progestin","display_name":"estrogen plus progestin","score":0.9150000214576721},{"id":"https://openalex.org/keywords/estrogen-only-therapy","display_name":"estrogen-only therapy","score":0.9890000224113464},{"id":"https://openalex.org/keywords/reproductive-factors","display_name":"reproductive factors","score":0.6330000162124634},{"id":"https://openalex.org/keywords/cancer-risk","display_name":"cancer risk","score":0.7360000014305115},{"id":"https://openalex.org/keywords/women-s-health-initiative","display_name":"Women's Health Initiative","score":0.8980000019073486}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8426312208175659},{"id":"https://openalex.org/C2781182431","wikidata":"https://www.wikidata.org/wiki/Q356033","display_name":"Adenocarcinoma","level":3,"score":0.6877037286758423},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.6326127052307129},{"id":"https://openalex.org/C2779742542","wikidata":"https://www.wikidata.org/wiki/Q372701","display_name":"Esophageal cancer","level":3,"score":0.5442928671836853},{"id":"https://openalex.org/C2776607906","wikidata":"https://www.wikidata.org/wiki/Q50383885","display_name":"Progestin","level":3,"score":0.533510684967041},{"id":"https://openalex.org/C143998085","wikidata":"https://www.wikidata.org/wiki/Q162555","display_name":"Oncology","level":1,"score":0.5251269936561584},{"id":"https://openalex.org/C2780275930","wikidata":"https://www.wikidata.org/wiki/Q1628266","display_name":"Hormone therapy","level":4,"score":0.4591497778892517},{"id":"https://openalex.org/C2777164284","wikidata":"https://www.wikidata.org/wiki/Q277954","display_name":"Estrogen","level":2,"score":0.4449983537197113},{"id":"https://openalex.org/C2777546739","wikidata":"https://www.wikidata.org/wiki/Q33525","display_name":"Carcinoma","level":2,"score":0.42332717776298523},{"id":"https://openalex.org/C90924648","wikidata":"https://www.wikidata.org/wiki/Q120569","display_name":"Gastroenterology","level":1,"score":0.4180573523044586},{"id":"https://openalex.org/C2992824209","wikidata":"https://www.wikidata.org/wiki/Q372701","display_name":"Esophageal adenocarcinoma","level":4,"score":0.41632384061813354},{"id":"https://openalex.org/C29456083","wikidata":"https://www.wikidata.org/wiki/Q1221899","display_name":"Gynecology","level":1,"score":0.3557945787906647},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.35208672285079956},{"id":"https://openalex.org/C530470458","wikidata":"https://www.wikidata.org/wiki/Q128581","display_name":"Breast cancer","level":3,"score":0.2814487814903259}],"mesh":[{"descriptor_ui":"D000230","descriptor_name":"Adenocarcinoma","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":false},{"descriptor_ui":"D000230","descriptor_name":"Adenocarcinoma","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":true},{"descriptor_ui":"D000230","descriptor_name":"Adenocarcinoma","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002294","descriptor_name":"Carcinoma, Squamous Cell","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":false},{"descriptor_ui":"D002294","descriptor_name":"Carcinoma, Squamous Cell","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":true},{"descriptor_ui":"D002294","descriptor_name":"Carcinoma, Squamous Cell","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D004938","descriptor_name":"Esophageal Neoplasms","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":false},{"descriptor_ui":"D004938","descriptor_name":"Esophageal Neoplasms","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":true},{"descriptor_ui":"D004938","descriptor_name":"Esophageal Neoplasms","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D004967","descriptor_name":"Estrogens","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005500","descriptor_name":"Follow-Up Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011372","descriptor_name":"Progestins","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":false},{"descriptor_ui":"D012307","descriptor_name":"Risk Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015994","descriptor_name":"Incidence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015996","descriptor_name":"Survival Rate","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016032","descriptor_name":"Randomized Controlled Trials as Topic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016896","descriptor_name":"Treatment Outcome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017698","descriptor_name":"Postmenopause","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D020249","descriptor_name":"Hormone Replacement Therapy","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":true}],"locations_count":4,"locations":[{"id":"doi:10.1158/1940-6207.capr-10-0389","doi":"https://doi.org/10.1158/1940-6207.capr-10-0389","is_oa":false,"landing_page_url":"https://doi.org/10.1158/1940-6207.capr-10-0389","pdf_url":null,"source":{"id":"https://openalex.org/S68240649","display_name":"Cancer Prevention Research","issn_l":"1940-6207","issn":["1940-6207","1940-6215"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320273","host_organization_name":"American Association for Cancer Research","host_organization_lineage":["https://openalex.org/P4310320273"],"host_organization_lineage_names":["American Association for Cancer Research"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cancer Prevention Research","raw_type":"journal-article"},{"id":"pmid:21505180","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/21505180","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cancer prevention research (Philadelphia, Pa.)","raw_type":"Journal Article"},{"id":"pmh:oai:europepmc.org:2368121","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3107894","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":null,"raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:3107894","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3107894","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"Cancer Prev Res (Phila)","raw_type":"Text"}],"best_oa_location":{"id":"pmh:oai:europepmc.org:2368121","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3107894","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":null,"raw_type":"Text"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":1.0}],"study_designs":[],"awards":[{"id":"https://openalex.org/G1113016571","display_name":"Women's Health Initiative","funder_award_id":"n01wh32105-27-0-1","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G1334132291","display_name":"Women's Health Initiative","funder_award_id":"n01wh32108-30-0-1","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G157098060","display_name":"Women's Health Initiative","funder_award_id":"n01wh32100-28-0-1","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G2130925301","display_name":"Women's Health Initiative","funder_award_id":"n01wh32118-27-0-1","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G3368529962","display_name":"Women's Health Initiative Memory Study (WHIMS)","funder_award_id":"n01wh44221-7-0-1","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G3568042507","display_name":"Women's Health Initiative","funder_award_id":"n01wh42129-23-0-1","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G4009987619","display_name":"Women's Health Initiative","funder_award_id":"n01wh32111-28-0-1","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G4051247052","display_name":"Women's Health Initiative","funder_award_id":"n01wh32115-26-0-1","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G413560588","display_name":null,"funder_award_id":"N01 WH 44221","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G4292434131","display_name":"COORDINATING CENTER FOR WOMEN'S HEALTH INITIATIVE","funder_award_id":"n01wh22110-38-0-0","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G429396632","display_name":null,"funder_award_id":"N01-WH-3-2115","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G445374210","display_name":null,"funder_award_id":"N01WH24152","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G526848650","display_name":"FOR ALL FIELD CENTER FOR WHI EXTENSION","funder_award_id":"n01wh24152-12-0-0","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G677860001","display_name":"Women's Health Initiative","funder_award_id":"n01wh32122-31-0-1","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G7084079823","display_name":"Estrogen Receptor 1 Gene, Adiposity, and Breast Cancer","funder_award_id":"K07CA136969","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"},{"id":"https://openalex.org/G7223985928","display_name":null,"funder_award_id":"N01-WH-3-2122","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G7279776621","display_name":"Women's Health Initiative","funder_award_id":"n01wh42107-22-0-1","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G85198494","display_name":"ESTABLISHED INVESTIGATOR AWARD IN CANCER PREVENTION AND CONTROL","funder_award_id":"K05CA124911","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"},{"id":"https://openalex.org/G9000002220","display_name":null,"funder_award_id":"N01WH42129-32","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G9000015938","display_name":null,"funder_award_id":"N01-WH-32108-9","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G9000016408","display_name":null,"funder_award_id":"N01WH 32111-13","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G9000029166","display_name":null,"funder_award_id":"N01 WH 32105-6","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G9000072420","display_name":null,"funder_award_id":"N01 WH022110","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G9000099044","display_name":null,"funder_award_id":"N01-WH-32100-2","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G9000151586","display_name":null,"funder_award_id":"N01-WH-42107-26","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G9000284018","display_name":null,"funder_award_id":"N01WH 32118-32119","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G9000880611","display_name":"Developing Data-Driven Cancer Researchers","funder_award_id":"T32CA009168","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"}],"funders":[{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337351","display_name":"National Cancer Institute","ror":"https://ror.org/040gcmg81"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":33,"referenced_works":["https://openalex.org/W1486933127","https://openalex.org/W1510648079","https://openalex.org/W1570627246","https://openalex.org/W1593002469","https://openalex.org/W1978548397","https://openalex.org/W1983391994","https://openalex.org/W1991553184","https://openalex.org/W1995000983","https://openalex.org/W2015764936","https://openalex.org/W2033374799","https://openalex.org/W2038953523","https://openalex.org/W2041630967","https://openalex.org/W2048962583","https://openalex.org/W2069358051","https://openalex.org/W2086584986","https://openalex.org/W2095527723","https://openalex.org/W2106758749","https://openalex.org/W2116389010","https://openalex.org/W2122380766","https://openalex.org/W2127164550","https://openalex.org/W2130497983","https://openalex.org/W2131301097","https://openalex.org/W2145378917","https://openalex.org/W2145724381","https://openalex.org/W2146020675","https://openalex.org/W2146417611","https://openalex.org/W2154505466","https://openalex.org/W2163009320","https://openalex.org/W2168512925","https://openalex.org/W2252310990","https://openalex.org/W2290627980","https://openalex.org/W2314540303","https://openalex.org/W4252560545"],"related_works":["https://openalex.org/W4316087067","https://openalex.org/W2562674637","https://openalex.org/W1497470272","https://openalex.org/W2139619993","https://openalex.org/W7137155244","https://openalex.org/W3207302946","https://openalex.org/W3164842039","https://openalex.org/W2135071054","https://openalex.org/W2739545714","https://openalex.org/W2127498693"],"abstract_inverted_index":{"The":[0],"incidences":[1],"of":[2,27,31,40,47,84,87,90,130,150,169,174,189,196,208,227],"esophageal":[3,32,48,68,72,91,122,175,209,217],"adenocarcinoma":[4,49,69],"and":[5,44,50,64,70,171],"squamous":[6],"cell":[7],"carcinoma":[8],"(SCC)":[9],"are":[10,23],"higher":[11],"in":[12,15,52,56,106,117,142,159],"males":[13],"than":[14],"females.":[16],"We":[17,34],"investigated":[18],"whether":[19],"female-related":[20],"hormonal":[21,181],"factors":[22,182],"associated":[24,185,203],"with":[25,186,204,216],"risks":[26,46],"these":[28],"two":[29],"types":[30],"cancer.":[33],"examined":[35],"the":[36,45,57,78,167,172,187],"association":[37,163,213],"between":[38,166],"use":[39,168,195],"hormone":[41],"therapy":[42,135,152,198],"(HT)":[43],"SCC":[51,73,92,123,191],"postmenopausal":[53],"women":[54],"enrolled":[55],"Women's":[58],"Health":[59],"Initiative":[60],"(WHI)":[61],"clinical":[62],"trials":[63],"observational":[65],"studies.":[66],"Twenty-three":[67],"34":[71],"cases":[74],"were":[75,183],"confirmed":[76],"among":[77,95],"161,080":[79],"participants,":[80],"after":[81],"a":[82,205,224,232],"median":[83],"11.82":[85],"years":[86],"follow-up.":[88],"Risk":[89],"was":[93,125,164,199,214],"lower":[94],"HT":[96,170],"users":[97,129,149],"(past":[98],"users:":[99,110],"HR":[100,111],"=":[101,112,137,154],"0.25,":[102,138],"95%":[103,114,139,156],"CI:":[104,115,140,157],"0.06-1.10":[105],"2":[107],"cases;":[108],"current":[109,128,148],"0.41,":[113],"0.18-0.94":[116],"9":[118],"cases).":[119,161],"A":[120],"decreased":[121,206],"risk":[124,173,188,207],"observed":[126,165,215],"for":[127,147],"estrogen":[131],"plus":[132],"progestin":[133],"(E+P)":[134],"(HR":[136,153],"0.07-0.86":[141],"3":[143],"cases)":[144],"but":[145,211],"not":[146],"estrogen-only":[151],"0.96,":[155],"0.28-3.29":[158],"6":[160],"No":[162,177],"adenocarcinoma.":[176,193,218],"other":[178],"reproductive":[179],"or":[180,192,231],"significantly":[184],"either":[190],"Current":[194],"E+P":[197],"found":[200],"to":[201],"be":[202,237],"SCC,":[210],"no":[212],"To":[219],"provide":[220],"more":[221],"definitive":[222],"evidence,":[223],"pooled":[225],"analysis":[226],"all":[228],"available":[229],"studies":[230],"much":[233],"larger":[234],"study":[235],"would":[236],"needed.":[238]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":3},{"year":2024,"cited_by_count":6},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":4},{"year":2021,"cited_by_count":6},{"year":2020,"cited_by_count":3},{"year":2019,"cited_by_count":6},{"year":2018,"cited_by_count":1},{"year":2017,"cited_by_count":5},{"year":2016,"cited_by_count":6},{"year":2015,"cited_by_count":4},{"year":2014,"cited_by_count":3},{"year":2013,"cited_by_count":1},{"year":2012,"cited_by_count":8}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}
