{"id":"https://openalex.org/W2125109199","doi":"https://doi.org/10.1161/01.cir.84.2.482","title":"Cardiovascular neural regulation explored in the frequency domain.","display_name":"Cardiovascular neural regulation explored in the frequency domain.","publication_year":1991,"publication_date":"1991-08-01","ids":{"openalex":"https://openalex.org/W2125109199","doi":"https://doi.org/10.1161/01.cir.84.2.482","mag":"2125109199","pmid":"https://pubmed.ncbi.nlm.nih.gov/1860193"},"language":"en","primary_location":{"id":"doi:10.1161/01.cir.84.2.482","doi":"https://doi.org/10.1161/01.cir.84.2.482","is_oa":true,"landing_page_url":"https://doi.org/10.1161/01.cir.84.2.482","pdf_url":"https://www.ahajournals.org/doi/pdf/10.1161/01.CIR.84.2.482","source":{"id":"https://openalex.org/S116251202","display_name":"Circulation","issn_l":"0009-7322","issn":["0009-7322","1524-4539"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Circulation","raw_type":"journal-article"},"volume":null,"type":"review","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://www.ahajournals.org/doi/pdf/10.1161/01.CIR.84.2.482","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5062683164","display_name":"Alberto Malliani","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"A Malliani","raw_affiliation_strings":["Istituto Ricerche Cardiovascolari, Centro Ricerche Cardiovascolari, CNR, Milano, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Istituto Ricerche Cardiovascolari, Centro Ricerche Cardiovascolari, CNR, Milano, Italy","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101809433","display_name":"M. Pagani","orcid":"https://orcid.org/0000-0001-9697-8959","observed_orcids":["https://orcid.org/0000-0001-9697-8959"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"M Pagani","raw_affiliation_strings":["Istituto Ricerche Cardiovascolari, Centro Ricerche Cardiovascolari, CNR, Milano, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Istituto Ricerche Cardiovascolari, Centro Ricerche Cardiovascolari, CNR, Milano, Italy","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5001390405","display_name":"Federico Lombardi","orcid":"https://orcid.org/0000-0003-2424-2509","observed_orcids":["https://orcid.org/0000-0003-2424-2509"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"F Lombardi","raw_affiliation_strings":["Istituto Ricerche Cardiovascolari, Centro Ricerche Cardiovascolari, CNR, Milano, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Istituto Ricerche Cardiovascolari, Centro Ricerche Cardiovascolari, CNR, Milano, Italy","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5017502703","display_name":"S. Cerutti","orcid":"https://orcid.org/0000-0002-9607-8755","observed_orcids":["https://orcid.org/0000-0002-9607-8755"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"S Cerutti","raw_affiliation_strings":["Istituto Ricerche Cardiovascolari, Centro Ricerche Cardiovascolari, CNR, Milano, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Istituto Ricerche Cardiovascolari, Centro Ricerche Cardiovascolari, CNR, Milano, Italy","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":11.7086,"has_fulltext":true,"cited_by_count":3599,"citation_normalized_percentile":{"value":0.99528302,"is_in_top_1_percent":true,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":99,"max":100},"biblio":{"volume":"84","issue":"2","first_page":"482","last_page":"492"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10745","display_name":"Heart Rate Variability and Autonomic Control","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10745","display_name":"Heart Rate Variability and Autonomic Control","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12580","display_name":"Vagus Nerve Stimulation Research","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2808","display_name":"Neurology"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10217","display_name":"Cardiac electrophysiology and arrhythmias","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/heart-rate-variability","display_name":"heart rate variability","score":0.9129999876022339},{"id":"https://openalex.org/keywords/sympathovagal-balance","display_name":"sympathovagal balance","score":0.9079999923706055},{"id":"https://openalex.org/keywords/parasympathetic-activity","display_name":"parasympathetic activity","score":0.6949999928474426},{"id":"https://openalex.org/keywords/sympathetic-nerve-activity","display_name":"sympathetic activity","score":0.9929999709129333},{"id":"https://openalex.org/keywords/blood-pressure-variability","display_name":"blood pressure variability","score":0.6060000061988831},{"id":"https://openalex.org/keywords/vasomotor-activity","display_name":"vasomotor activity","score":0.8450000286102295},{"id":"https://openalex.org/keywords/frequency-domain-analysis","display_name":"frequency domain analysis","score":0.5730000138282776},{"id":"https://openalex.org/keywords/autonomic-regulation","display_name":"autonomic regulation","score":0.46299999952316284}],"concepts":[{"id":"https://openalex.org/C2776214587","wikidata":"https://www.wikidata.org/wiki/Q3430227","display_name":"Vasomotor","level":2,"score":0.6957492232322693},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.6764750480651855},{"id":"https://openalex.org/C71635504","wikidata":"https://www.wikidata.org/wiki/Q933954","display_name":"Heart rate variability","level":4,"score":0.6262717247009277},{"id":"https://openalex.org/C168031717","wikidata":"https://www.wikidata.org/wiki/Q1530280","display_name":"Balance (ability)","level":2,"score":0.5947535634040833},{"id":"https://openalex.org/C3020789104","wikidata":"https://www.wikidata.org/wiki/Q187215","display_name":"Sympathetic activity","level":4,"score":0.5833185315132141},{"id":"https://openalex.org/C17077164","wikidata":"https://www.wikidata.org/wiki/Q1185869","display_name":"Inhibitory postsynaptic potential","level":2,"score":0.5724039673805237},{"id":"https://openalex.org/C112592302","wikidata":"https://www.wikidata.org/wiki/Q1207387","display_name":"Excitatory postsynaptic potential","level":3,"score":0.5664994120597839},{"id":"https://openalex.org/C83974742","wikidata":"https://www.wikidata.org/wiki/Q179405","display_name":"Reflex","level":2,"score":0.564119815826416},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.5253661870956421},{"id":"https://openalex.org/C135343436","wikidata":"https://www.wikidata.org/wiki/Q170406","display_name":"Rhythm","level":2,"score":0.4895959496498108},{"id":"https://openalex.org/C2777372248","wikidata":"https://www.wikidata.org/wiki/Q171064","display_name":"Autonomic nervous system","level":4,"score":0.420513391494751},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.40411630272865295},{"id":"https://openalex.org/C2777953023","wikidata":"https://www.wikidata.org/wiki/Q1073121","display_name":"Heart rate","level":3,"score":0.39991897344589233},{"id":"https://openalex.org/C164705383","wikidata":"https://www.wikidata.org/wiki/Q10379","display_name":"Cardiology","level":1,"score":0.36829566955566406},{"id":"https://openalex.org/C84393581","wikidata":"https://www.wikidata.org/wiki/Q82642","display_name":"Blood pressure","level":2,"score":0.1696600317955017},{"id":"https://openalex.org/C99508421","wikidata":"https://www.wikidata.org/wiki/Q2678675","display_name":"Physical medicine and rehabilitation","level":1,"score":0.1609349548816681},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.13187023997306824}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002309","descriptor_name":"Cardiology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D002319","descriptor_name":"Cardiovascular System","qualifier_ui":"Q000294","qualifier_name":"innervation","is_major_topic":true},{"descriptor_ui":"D003327","descriptor_name":"Coronary Disease","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D006329","descriptor_name":"Heart Conduction System","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D006333","descriptor_name":"Heart Failure","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006973","descriptor_name":"Hypertension","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D009420","descriptor_name":"Nervous System","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D009424","descriptor_name":"Nervous System Physiological Phenomena","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013564","descriptor_name":"Sympathetic Nervous System","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D014630","descriptor_name":"Vagus Nerve","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D016027","descriptor_name":"Heart Transplantation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.1161/01.cir.84.2.482","doi":"https://doi.org/10.1161/01.cir.84.2.482","is_oa":true,"landing_page_url":"https://doi.org/10.1161/01.cir.84.2.482","pdf_url":"https://www.ahajournals.org/doi/pdf/10.1161/01.CIR.84.2.482","source":{"id":"https://openalex.org/S116251202","display_name":"Circulation","issn_l":"0009-7322","issn":["0009-7322","1524-4539"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Circulation","raw_type":"journal-article"},{"id":"pmid:1860193","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/1860193","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Circulation","raw_type":"Journal Article"},{"id":"pmh:oai:re.public.polimi.it:11311/665888","doi":null,"is_oa":false,"landing_page_url":"http://hdl.handle.net/11311/665888","pdf_url":null,"source":{"id":"https://openalex.org/S4306400312","display_name":"Virtual Community of Pathological Anatomy (University of Castilla La Mancha)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I79189158","host_organization_name":"University of Castilla-La Mancha","host_organization_lineage":["https://openalex.org/I79189158"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"info:eu-repo/semantics/article"},{"id":"mag:3144356861","doi":null,"is_oa":false,"landing_page_url":"https://www.ahajournals.org/doi/abs/10.1161/circ.84.2.1860193?related-urls=yes&legid=circulationaha%3B84%2F2%2F482&legid=circulationaha%3B84%2F2%2F482&cited-by=yes","pdf_url":null,"source":{"id":"https://openalex.org/S116251202","display_name":"Circulation","issn_l":"0009-7322","issn":["0009-7322","1524-4539"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"Circulation","raw_type":null}],"best_oa_location":{"id":"doi:10.1161/01.cir.84.2.482","doi":"https://doi.org/10.1161/01.cir.84.2.482","is_oa":true,"landing_page_url":"https://doi.org/10.1161/01.cir.84.2.482","pdf_url":"https://www.ahajournals.org/doi/pdf/10.1161/01.CIR.84.2.482","source":{"id":"https://openalex.org/S116251202","display_name":"Circulation","issn_l":"0009-7322","issn":["0009-7322","1524-4539"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Circulation","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.6240000128746033,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2125109199.pdf","grobid_xml":"https://content.openalex.org/works/W2125109199.grobid-xml"},"referenced_works_count":69,"referenced_works":["https://openalex.org/W131135619","https://openalex.org/W359190940","https://openalex.org/W1562886527","https://openalex.org/W1750537116","https://openalex.org/W1869307176","https://openalex.org/W1967900132","https://openalex.org/W1970530324","https://openalex.org/W1973379750","https://openalex.org/W1974485413","https://openalex.org/W1974713020","https://openalex.org/W1978667936","https://openalex.org/W1979741060","https://openalex.org/W1983580904","https://openalex.org/W1992901058","https://openalex.org/W1996683481","https://openalex.org/W2003890842","https://openalex.org/W2010467854","https://openalex.org/W2017133647","https://openalex.org/W2020021873","https://openalex.org/W2021669309","https://openalex.org/W2022496931","https://openalex.org/W2023233510","https://openalex.org/W2027865289","https://openalex.org/W2029916807","https://openalex.org/W2032199624","https://openalex.org/W2032793274","https://openalex.org/W2039728997","https://openalex.org/W2049803512","https://openalex.org/W2053421560","https://openalex.org/W2054340269","https://openalex.org/W2056725529","https://openalex.org/W2059590433","https://openalex.org/W2060853165","https://openalex.org/W2062693033","https://openalex.org/W2062841973","https://openalex.org/W2066125362","https://openalex.org/W2068898649","https://openalex.org/W2069043463","https://openalex.org/W2069501748","https://openalex.org/W2070806736","https://openalex.org/W2072141983","https://openalex.org/W2075281407","https://openalex.org/W2087647360","https://openalex.org/W2088993525","https://openalex.org/W2098186057","https://openalex.org/W2108000303","https://openalex.org/W2112400936","https://openalex.org/W2116337118","https://openalex.org/W2121832960","https://openalex.org/W2135824932","https://openalex.org/W2138851126","https://openalex.org/W2153087708","https://openalex.org/W2157834058","https://openalex.org/W2158361166","https://openalex.org/W2159402223","https://openalex.org/W2159474374","https://openalex.org/W2159722103","https://openalex.org/W2162443378","https://openalex.org/W2163183941","https://openalex.org/W2218308347","https://openalex.org/W2289526231","https://openalex.org/W2301665936","https://openalex.org/W2320558234","https://openalex.org/W2335199918","https://openalex.org/W2341773287","https://openalex.org/W2345518962","https://openalex.org/W2442246255","https://openalex.org/W3035924285","https://openalex.org/W4285719527"],"related_works":["https://openalex.org/W2404507462","https://openalex.org/W2033544030","https://openalex.org/W2437951962","https://openalex.org/W1986827320","https://openalex.org/W2419500379","https://openalex.org/W3020994955","https://openalex.org/W134954727","https://openalex.org/W2108824181","https://openalex.org/W2145926418","https://openalex.org/W1531145115"],"abstract_inverted_index":{"A":[0],"consistent":[1],"link":[2],"appears":[3,134],"to":[4,33,76,94,135,168],"exist":[5],"between":[6],"predominance":[7,14],"of":[8,15,25,83,107,113,140,144,158,173,179],"vagal":[9,79,124],"or":[10,17,65],"sympathetic":[11,81,100,142],"activity":[12,101],"and":[13,28,54,62,67,71,80,88],"HF":[16],"LF":[18,115,128],"oscillations,":[19],"respectively:":[20],"RR":[21],"variability":[22,133],"contains":[23],"both":[24],"these":[26],"rhythms,":[27],"their":[29],"relative":[30],"powers":[31],"appear":[32],"subserve":[34],"a":[35,105,137,164],"reciprocal":[36],"relation":[37],"like":[38,60],"that":[39,52,72],"commonly":[40],"found":[41],"in":[42,111,123,154],"sympathovagal":[43],"balance.":[44],"In":[45,86,126],"this":[46],"respect,":[47],"it":[48,73],"is":[49,74],"our":[50],"opinion":[51],"rhythms":[53],"neural":[55,160],"components":[56],"always":[57],"interact,":[58],"just":[59],"flexor":[61],"extensor":[63],"tones":[64],"excitatory":[66],"inhibitory":[68],"cardiovascular":[69,159],"reflexes,":[70],"misleading":[75],"separately":[77],"consider":[78],"modulations":[82],"heart":[84],"rate.":[85],"humans":[87],"experimental":[89],"animals,":[90],"functional":[91],"states":[92],"likely":[93],"be":[95,136],"accompanied":[96],"by":[97,104],"an":[98],"increased":[99],"are":[102],"characterized":[103],"shift":[106],"the":[108,114,117,141,152,155,171],"LF-HF":[109],"balance":[110],"favor":[112],"component;":[116],"opposite":[118],"occurs":[119],"during":[120],"presumed":[121],"increases":[122],"activity.":[125,146],"addition,":[127],"oscillation":[129],"evaluated":[130],"from":[131],"SAP":[132],"convenient":[138],"marker":[139],"modulation":[143],"vasomotor":[145],"Although":[147],"based":[148],"on":[149],"indirect":[150],"markers,":[151],"exploration":[153],"frequency":[156],"domain":[157],"regulation":[161],"might":[162],"disclose":[163],"unitary":[165],"vision":[166],"hard":[167],"reach":[169],"through":[170],"assemblage":[172],"more":[174],"specific":[175],"but":[176],"fragmented":[177],"pieces":[178],"information.":[180]},"counts_by_year":[{"year":2026,"cited_by_count":41},{"year":2025,"cited_by_count":61},{"year":2024,"cited_by_count":51},{"year":2023,"cited_by_count":68},{"year":2022,"cited_by_count":91},{"year":2021,"cited_by_count":102},{"year":2020,"cited_by_count":115},{"year":2019,"cited_by_count":94},{"year":2018,"cited_by_count":124},{"year":2017,"cited_by_count":144},{"year":2016,"cited_by_count":119},{"year":2015,"cited_by_count":123},{"year":2014,"cited_by_count":140},{"year":2013,"cited_by_count":141},{"year":2012,"cited_by_count":120}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2016-06-24T00:00:00"}