{"id":"https://openalex.org/W2124885959","doi":"https://doi.org/10.1006/viro.1993.1408","title":"Twenty-One Base Pair Repeat Elements Influence the Ability of a Gal4-Tax Fusion Protein to Transactivate the HTLV-I Long Terminal Repeat","display_name":"Twenty-One Base Pair Repeat Elements Influence the Ability of a Gal4-Tax Fusion Protein to Transactivate the HTLV-I Long Terminal Repeat","publication_year":1993,"publication_date":"1993-08-01","ids":{"openalex":"https://openalex.org/W2124885959","doi":"https://doi.org/10.1006/viro.1993.1408","mag":"2124885959","pmid":"https://pubmed.ncbi.nlm.nih.gov/8337832"},"language":"en","primary_location":{"id":"doi:10.1006/viro.1993.1408","doi":"https://doi.org/10.1006/viro.1993.1408","is_oa":false,"landing_page_url":"https://doi.org/10.1006/viro.1993.1408","pdf_url":null,"source":{"id":"https://openalex.org/S6147291","display_name":"Virology","issn_l":"0042-6822","issn":["0042-6822","1089-862X","1096-0341"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Virology","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5111511638","display_name":"Laurie M. Connor","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]},{"id":"https://openalex.org/I181547552","display_name":"Baylor College of Medicine","ror":"https://ror.org/02pttbw34","country_code":"US","type":"education","lineage":["https://openalex.org/I181547552","https://openalex.org/I2801539370"]},{"id":"https://openalex.org/I4210140884","display_name":"National Cancer Institute","ror":"https://ror.org/040gcmg81","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210140884"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Laurie M. Connor","raw_affiliation_strings":["Division of Molecular Virology, Baylor College of Medicine, Houston, Texas 77030","Division of Molecular Virology, Baylor College of Medicine, One Baylor Plaza, Houston, Texas 77030","Laboratory of Molecular Virology, National Cancer Institute, Bethesda, Maryland, 20892"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Molecular Virology, Baylor College of Medicine, Houston, Texas 77030","institution_ids":["https://openalex.org/I181547552"]},{"raw_affiliation_string":"Division of Molecular Virology, Baylor College of Medicine, One Baylor Plaza, Houston, Texas 77030","institution_ids":["https://openalex.org/I181547552"]},{"raw_affiliation_string":"Laboratory of Molecular Virology, National Cancer Institute, Bethesda, Maryland, 20892","institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I4210140884"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5108073611","display_name":"Michael N. Oxman","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]},{"id":"https://openalex.org/I181547552","display_name":"Baylor College of Medicine","ror":"https://ror.org/02pttbw34","country_code":"US","type":"education","lineage":["https://openalex.org/I181547552","https://openalex.org/I2801539370"]},{"id":"https://openalex.org/I4210140884","display_name":"National Cancer Institute","ror":"https://ror.org/040gcmg81","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210140884"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Michael N. Oxman","raw_affiliation_strings":["Division of Molecular Virology, Baylor College of Medicine, One Baylor Plaza, Houston, Texas 77030; and Laboratory of Molecular Virology, National Cancer Institute, Bethesda, Maryland, 20892","Division of Molecular Virology, Baylor College of Medicine, One Baylor Plaza, Houston, Texas 77030","Laboratory of Molecular Virology, National Cancer Institute, Bethesda, Maryland, 20892"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Molecular Virology, Baylor College of Medicine, One Baylor Plaza, Houston, Texas 77030; and Laboratory of Molecular Virology, National Cancer Institute, Bethesda, Maryland, 20892","institution_ids":["https://openalex.org/I181547552","https://openalex.org/I4210140884"]},{"raw_affiliation_string":"Division of Molecular Virology, Baylor College of Medicine, One Baylor Plaza, Houston, Texas 77030","institution_ids":["https://openalex.org/I181547552"]},{"raw_affiliation_string":"Laboratory of Molecular Virology, National Cancer Institute, Bethesda, Maryland, 20892","institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I4210140884"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109269727","display_name":"John N Brady","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]},{"id":"https://openalex.org/I181547552","display_name":"Baylor College of Medicine","ror":"https://ror.org/02pttbw34","country_code":"US","type":"education","lineage":["https://openalex.org/I181547552","https://openalex.org/I2801539370"]},{"id":"https://openalex.org/I4210140884","display_name":"National Cancer Institute","ror":"https://ror.org/040gcmg81","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210140884"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"John N. Brady","raw_affiliation_strings":["Division of Molecular Virology, Baylor College of Medicine, One Baylor Plaza, Houston, Texas 77030; and Laboratory of Molecular Virology, National Cancer Institute, Bethesda, Maryland, 20892","Division of Molecular Virology, Baylor College of Medicine, One Baylor Plaza, Houston, Texas 77030","Laboratory of Molecular Virology, National Cancer Institute, Bethesda, Maryland, 20892"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Molecular Virology, Baylor College of Medicine, One Baylor Plaza, Houston, Texas 77030; and Laboratory of Molecular Virology, National Cancer Institute, Bethesda, Maryland, 20892","institution_ids":["https://openalex.org/I181547552","https://openalex.org/I4210140884"]},{"raw_affiliation_string":"Division of Molecular Virology, Baylor College of Medicine, One Baylor Plaza, Houston, Texas 77030","institution_ids":["https://openalex.org/I181547552"]},{"raw_affiliation_string":"Laboratory of Molecular Virology, National Cancer Institute, Bethesda, Maryland, 20892","institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I4210140884"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5017090665","display_name":"Susan J. Marriott","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]},{"id":"https://openalex.org/I181547552","display_name":"Baylor College of Medicine","ror":"https://ror.org/02pttbw34","country_code":"US","type":"education","lineage":["https://openalex.org/I181547552","https://openalex.org/I2801539370"]},{"id":"https://openalex.org/I4210140884","display_name":"National Cancer Institute","ror":"https://ror.org/040gcmg81","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210140884"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Susan J. Marriott","raw_affiliation_strings":["Division of Molecular Virology, Baylor College of Medicine, One Baylor Plaza, Houston, Texas 77030; and Laboratory of Molecular Virology, National Cancer Institute, Bethesda, Maryland, 20892","Division of Molecular Virology, Baylor College of Medicine, One Baylor Plaza, Houston, Texas 77030","Laboratory of Molecular Virology, National Cancer Institute, Bethesda, Maryland, 20892"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Molecular Virology, Baylor College of Medicine, One Baylor Plaza, Houston, Texas 77030; and Laboratory of Molecular Virology, National Cancer Institute, Bethesda, Maryland, 20892","institution_ids":["https://openalex.org/I181547552","https://openalex.org/I4210140884"]},{"raw_affiliation_string":"Division of Molecular Virology, Baylor College of Medicine, One Baylor Plaza, Houston, Texas 77030","institution_ids":["https://openalex.org/I181547552"]},{"raw_affiliation_string":"Laboratory of Molecular Virology, National Cancer Institute, Bethesda, Maryland, 20892","institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I4210140884"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":3160,"currency":"USD","value_usd":3160},"apc_paid":null,"fwci":1.8429,"has_fulltext":false,"cited_by_count":22,"citation_normalized_percentile":{"value":0.86480703,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"195","issue":"2","first_page":"569","last_page":"577"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12159","display_name":"T-cell and Retrovirus Studies","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T12159","display_name":"T-cell and Retrovirus Studies","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10222","display_name":"Genomics and Chromatin Dynamics","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10112","display_name":"HIV Research and Treatment","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2406","display_name":"Virology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/htlv-1","display_name":"HTLV-1","score":0.8259999752044678},{"id":"https://openalex.org/keywords/long-terminal-repeat","display_name":"long terminal repeat","score":0.9259999990463257},{"id":"https://openalex.org/keywords/transcriptional-activation","display_name":"transcriptional activation","score":0.781000018119812},{"id":"https://openalex.org/keywords/transcription-factors","display_name":"transcription factors","score":0.9120000004768372},{"id":"https://openalex.org/keywords/viral-transcription","display_name":"viral transcription","score":0.39800000190734863},{"id":"https://openalex.org/keywords/ltr-promoter","display_name":"LTR promoter","score":0.49300000071525574}],"concepts":[{"id":"https://openalex.org/C1292079","wikidata":"https://www.wikidata.org/wiki/Q3817769","display_name":"Transactivation","level":4,"score":0.8766292333602905},{"id":"https://openalex.org/C199491388","wikidata":"https://www.wikidata.org/wiki/Q1869477","display_name":"Long terminal repeat","level":4,"score":0.7959619760513306},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.7392007112503052},{"id":"https://openalex.org/C179926584","wikidata":"https://www.wikidata.org/wiki/Q207714","display_name":"Transcription (linguistics)","level":2,"score":0.6084154844284058},{"id":"https://openalex.org/C86339819","wikidata":"https://www.wikidata.org/wiki/Q407384","display_name":"Transcription factor","level":3,"score":0.5764360427856445},{"id":"https://openalex.org/C123894998","wikidata":"https://www.wikidata.org/wiki/Q425158","display_name":"Fusion protein","level":4,"score":0.5043145418167114},{"id":"https://openalex.org/C552990157","wikidata":"https://www.wikidata.org/wiki/Q7430","display_name":"DNA","level":2,"score":0.4999992847442627},{"id":"https://openalex.org/C33987129","wikidata":"https://www.wikidata.org/wiki/Q13479514","display_name":"DNA-binding domain","level":4,"score":0.4831952154636383},{"id":"https://openalex.org/C161733203","wikidata":"https://www.wikidata.org/wiki/Q911828","display_name":"Reporter gene","level":4,"score":0.43643295764923096},{"id":"https://openalex.org/C107824862","wikidata":"https://www.wikidata.org/wiki/Q616005","display_name":"Binding site","level":2,"score":0.4259741008281708},{"id":"https://openalex.org/C153911025","wikidata":"https://www.wikidata.org/wiki/Q7202","display_name":"Molecular biology","level":1,"score":0.39721935987472534},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.35054710507392883},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.2989860773086548},{"id":"https://openalex.org/C40767141","wikidata":"https://www.wikidata.org/wiki/Q285697","display_name":"Recombinant DNA","level":3,"score":0.2058093547821045},{"id":"https://openalex.org/C150194340","wikidata":"https://www.wikidata.org/wiki/Q26972","display_name":"Gene expression","level":3,"score":0.16685351729393005},{"id":"https://openalex.org/C138885662","wikidata":"https://www.wikidata.org/wiki/Q5891","display_name":"Philosophy","level":0,"score":0.0},{"id":"https://openalex.org/C41895202","wikidata":"https://www.wikidata.org/wiki/Q8162","display_name":"Linguistics","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000595","descriptor_name":"Amino Acid Sequence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001482","descriptor_name":"Base Composition","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001483","descriptor_name":"Base Sequence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001665","descriptor_name":"Binding Sites","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004268","descriptor_name":"DNA-Binding Proteins","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004279","descriptor_name":"DNA, Viral","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005656","descriptor_name":"Fungal Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D005656","descriptor_name":"Fungal Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D006367","descriptor_name":"HeLa Cells","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008969","descriptor_name":"Molecular Sequence Data","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011401","descriptor_name":"Promoter Regions, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011993","descriptor_name":"Recombinant Fusion Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D012091","descriptor_name":"Repetitive Sequences, Nucleic Acid","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D014157","descriptor_name":"Transcription Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D015368","descriptor_name":"Human T-lymphotropic virus 1","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D015533","descriptor_name":"Transcriptional Activation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D016356","descriptor_name":"Gene Products, tax","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D016356","descriptor_name":"Gene Products, tax","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D029701","descriptor_name":"Saccharomyces cerevisiae Proteins","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1006/viro.1993.1408","doi":"https://doi.org/10.1006/viro.1993.1408","is_oa":false,"landing_page_url":"https://doi.org/10.1006/viro.1993.1408","pdf_url":null,"source":{"id":"https://openalex.org/S6147291","display_name":"Virology","issn_l":"0042-6822","issn":["0042-6822","1089-862X","1096-0341"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Virology","raw_type":"journal-article"},{"id":"pmid:8337832","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/8337832","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Virology","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G4014155298","display_name":"Transcriptional Regulation of HTLV Gene Expression","funder_award_id":"R01CA055684","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"},{"id":"https://openalex.org/G7986064516","display_name":null,"funder_award_id":"1R01CA55684-01","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"}],"funders":[{"id":"https://openalex.org/F4320337351","display_name":"National Cancer Institute","ror":"https://ror.org/040gcmg81"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2135506398","https://openalex.org/W2320324219","https://openalex.org/W1508549696","https://openalex.org/W2462342909","https://openalex.org/W2000090884","https://openalex.org/W2106144352","https://openalex.org/W2423209621","https://openalex.org/W1865665406","https://openalex.org/W1593631074","https://openalex.org/W2162623315"],"abstract_inverted_index":null,"counts_by_year":[],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}