{"id":"https://openalex.org/W2124766730","doi":"https://doi.org/10.1001/archderm.125.6.824","title":"Phototoxicity of Nonsteroidal Inflammatory Drugs","display_name":"Phototoxicity of Nonsteroidal Inflammatory Drugs","publication_year":1989,"publication_date":"1989-06-01","ids":{"openalex":"https://openalex.org/W2124766730","doi":"https://doi.org/10.1001/archderm.125.6.824","mag":"2124766730","pmid":"https://pubmed.ncbi.nlm.nih.gov/2730104"},"language":"en","primary_location":{"id":"doi:10.1001/archderm.125.6.824","doi":"https://doi.org/10.1001/archderm.125.6.824","is_oa":false,"landing_page_url":"https://doi.org/10.1001/archderm.125.6.824","pdf_url":null,"source":{"id":"https://openalex.org/S115046667","display_name":"Archives of Dermatology","issn_l":"0003-987X","issn":["0003-987X","1538-3652"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core"],"host_organization":"https://openalex.org/P4310320259","host_organization_name":"American Medical Association","host_organization_lineage":["https://openalex.org/P4310320259"],"host_organization_lineage_names":["American Medical Association"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Archives of Dermatology","raw_type":"journal-article"},"volume":null,"type":"editorial","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5097722850","display_name":"I. E. Kocheva","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"I. E. Kocheva","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":["https://openalex.org/A5097722850"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":83,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":"125","issue":"6","first_page":"824","last_page":"824"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11117","display_name":"Drug-Induced Adverse Reactions","score":0.6220999956130981,"subfield":{"id":"https://openalex.org/subfields/2736","display_name":"Pharmacology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11117","display_name":"Drug-Induced Adverse Reactions","score":0.6220999956130981,"subfield":{"id":"https://openalex.org/subfields/2736","display_name":"Pharmacology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11013","display_name":"Skin Protection and Aging","score":0.1720999926328659,"subfield":{"id":"https://openalex.org/subfields/2708","display_name":"Dermatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11033","display_name":"Contact Dermatitis and Allergies","score":0.09989999979734421,"subfield":{"id":"https://openalex.org/subfields/2708","display_name":"Dermatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/nonsteroidal-anti-inflammatory-drugs","display_name":"nonsteroidal anti-inflammatory drugs","score":0.8949999809265137},{"id":"https://openalex.org/keywords/phototoxicity","display_name":"phototoxicity","score":0.9369999766349792},{"id":"https://openalex.org/keywords/skin-photosensitivity","display_name":"skin photosensitivity","score":0.9670000076293945},{"id":"https://openalex.org/keywords/phenylpropionic-acid-derivatives","display_name":"phenylpropionic acid derivatives","score":0.902999997138977},{"id":"https://openalex.org/keywords/nabumetone","display_name":"nabumetone","score":0.8790000081062317},{"id":"https://openalex.org/keywords/benoxaprofen","display_name":"benoxaprofen","score":0.9769999980926514},{"id":"https://openalex.org/keywords/ketoprofen","display_name":"ketoprofen","score":0.7850000262260437},{"id":"https://openalex.org/keywords/naproxen","display_name":"naproxen","score":0.8190000057220459},{"id":"https://openalex.org/keywords/ultraviolet-radiation","display_name":"ultraviolet radiation","score":0.8190000057220459},{"id":"https://openalex.org/keywords/drug-induced-photosensitivity","display_name":"drug-induced photosensitivity","score":0.6320000290870667}],"concepts":[{"id":"https://openalex.org/C20639190","wikidata":"https://www.wikidata.org/wiki/Q2088972","display_name":"Phototoxicity","level":3,"score":0.9467731714248657},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9216557145118713},{"id":"https://openalex.org/C2778484676","wikidata":"https://www.wikidata.org/wiki/Q20707196","display_name":"Nonsteroidal","level":2,"score":0.8704401254653931},{"id":"https://openalex.org/C89611455","wikidata":"https://www.wikidata.org/wiki/Q6804646","display_name":"Mechanism (biology)","level":2,"score":0.5890588164329529},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.4337931275367737},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0},{"id":"https://openalex.org/C202751555","wikidata":"https://www.wikidata.org/wiki/Q221681","display_name":"In vitro","level":2,"score":0.0},{"id":"https://openalex.org/C138885662","wikidata":"https://www.wikidata.org/wiki/Q5891","display_name":"Philosophy","level":0,"score":0.0},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.0},{"id":"https://openalex.org/C111472728","wikidata":"https://www.wikidata.org/wiki/Q9471","display_name":"Epistemology","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000894","descriptor_name":"Anti-Inflammatory Agents, Non-Steroidal","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010666","descriptor_name":"Phenylpropionates","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":false},{"descriptor_ui":"D010787","descriptor_name":"Photosensitivity Disorders","qualifier_ui":"Q000139","qualifier_name":"chemically induced","is_major_topic":true},{"descriptor_ui":"D014466","descriptor_name":"Ultraviolet Rays","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1001/archderm.125.6.824","doi":"https://doi.org/10.1001/archderm.125.6.824","is_oa":false,"landing_page_url":"https://doi.org/10.1001/archderm.125.6.824","pdf_url":null,"source":{"id":"https://openalex.org/S115046667","display_name":"Archives of Dermatology","issn_l":"0003-987X","issn":["0003-987X","1538-3652"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core"],"host_organization":"https://openalex.org/P4310320259","host_organization_name":"American Medical Association","host_organization_lineage":["https://openalex.org/P4310320259"],"host_organization_lineage_names":["American Medical Association"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Archives of Dermatology","raw_type":"journal-article"},{"id":"doi:10.1001/archderm.1989.01670180096016","doi":"https://doi.org/10.1001/archderm.1989.01670180096016","is_oa":false,"landing_page_url":"https://doi.org/10.1001/archderm.1989.01670180096016","pdf_url":null,"source":{"id":"https://openalex.org/S115046667","display_name":"Archives of Dermatology","issn_l":"0003-987X","issn":["0003-987X","1538-3652"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core"],"host_organization":"https://openalex.org/P4310320259","host_organization_name":"American Medical Association","host_organization_lineage":["https://openalex.org/P4310320259"],"host_organization_lineage_names":["American Medical Association"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Archives of Dermatology","raw_type":"journal-article"},{"id":"pmid:2730104","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/2730104","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Archives of dermatology","raw_type":"Editorial"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.9391000270843506,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":25,"referenced_works":["https://openalex.org/W8796496","https://openalex.org/W1522992067","https://openalex.org/W1971209547","https://openalex.org/W1975992455","https://openalex.org/W1988314739","https://openalex.org/W2003448376","https://openalex.org/W2011935546","https://openalex.org/W2015502139","https://openalex.org/W2018819945","https://openalex.org/W2021943988","https://openalex.org/W2030573856","https://openalex.org/W2040733513","https://openalex.org/W2044876729","https://openalex.org/W2045578082","https://openalex.org/W2068153669","https://openalex.org/W2088512269","https://openalex.org/W2112197427","https://openalex.org/W2168987605","https://openalex.org/W2398167167","https://openalex.org/W2405026158","https://openalex.org/W2412825974","https://openalex.org/W2416412047","https://openalex.org/W2462580167","https://openalex.org/W2621720568","https://openalex.org/W4247344599"],"related_works":["https://openalex.org/W4237464973","https://openalex.org/W2168987605","https://openalex.org/W227615345","https://openalex.org/W133126651","https://openalex.org/W8796496","https://openalex.org/W69612631","https://openalex.org/W2047719652","https://openalex.org/W2964206393","https://openalex.org/W2413686966","https://openalex.org/W2905567179"],"abstract_inverted_index":{"Reports":[0],"of":[1,32,37,68,82,126],"cutaneous":[2,108],"photosensitivity":[3,72,109],"to":[4,43,89,101,110,113,128],"new":[5,91],"pharmaceutical":[6],"agents":[7,41],"appear":[8],"almost":[9],"every":[10],"year.1,2Among":[11],"drugs":[12,17],"causing":[13,71],"photosensitivity,":[14],"nonsteroidal":[15],"inflammatory":[16],"(NSAIDs)":[18],"stand":[19],"out:":[20],"first,":[21],"because":[22,36],"they":[23],"are":[24,51,73],"reported":[25],"on":[26,97],"more":[27],"frequently":[28],"than":[29],"other":[30],"types":[31],"drugs,":[33],"and":[34,85],"second,":[35],"the":[38,69],"incongruity":[39],"that":[40],"designed":[42],"inhibit":[44],"inflammation":[45],"actually":[46],"cause":[47],"light-initiated":[48],"inflammation.":[49],"Why":[50],"many":[52],"NSAIDs":[53,70,104,111],"photosensitizing?":[54],"Is":[55],"it":[56],"just":[57],"an":[58],"odd":[59],"coincidence":[60],"or":[61],"is":[62,122],"a":[63,90,117],"specific":[64],"mechanism":[65],"responsible?":[66],"Most":[67],"phenylpropionic":[74],"acid":[75],"derivatives:":[76],"benoxaprofen,3-7carprofen,8ketoprofen,9tiaprofenic":[77],"acid,10and":[78],"naproxen.10In":[79],"this":[80,87],"issue":[81],"theArchives,":[83],"Kaidby":[84],"Mitchell11extend":[86],"list":[88],"NSAID,":[92],"nabumetone,":[93],"in":[94,105],"their":[95],"report":[96],"experimentally":[98],"induced":[99],"phototoxicity":[100,118],"propionic":[102],"acid-derivative":[103],"volunteers.":[106],"The":[107,120],"appears":[112],"be":[114],"elicited":[115],"by":[116],"mechanism.":[119],"response":[121],"immediate":[123],"(within":[124],"minutes":[125],"exposure":[127],"ultraviolet":[129],"[UV]":[130],"radiation)":[131],"for":[132],"benoxaprofen,":[133],"naproxen,":[134]},"counts_by_year":[{"year":2024,"cited_by_count":3},{"year":2015,"cited_by_count":1},{"year":2014,"cited_by_count":1},{"year":2013,"cited_by_count":1},{"year":2012,"cited_by_count":6}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}