{"id":"https://openalex.org/W2124766090","doi":"https://doi.org/10.1152/ajpheart.1999.276.4.h1117","title":"Beneficial effect of myocardial angiogenesis on cardiac remodeling process by amlodipine and MCI-154","display_name":"Beneficial effect of myocardial angiogenesis on cardiac remodeling process by amlodipine and MCI-154","publication_year":1999,"publication_date":"1999-04-01","ids":{"openalex":"https://openalex.org/W2124766090","doi":"https://doi.org/10.1152/ajpheart.1999.276.4.h1117","mag":"2124766090","pmid":"https://pubmed.ncbi.nlm.nih.gov/10199832"},"language":"en","primary_location":{"id":"doi:10.1152/ajpheart.1999.276.4.h1117","doi":"https://doi.org/10.1152/ajpheart.1999.276.4.h1117","is_oa":false,"landing_page_url":"https://doi.org/10.1152/ajpheart.1999.276.4.h1117","pdf_url":null,"source":{"id":"https://openalex.org/S87338489","display_name":"American Journal of Physiology-Heart and Circulatory Physiology","issn_l":"0363-6135","issn":["0363-6135","1522-1539"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-a","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320261","host_organization_name":"American Physical Society","host_organization_lineage":["https://openalex.org/P4310320261"],"host_organization_lineage_names":["American Physical Society"],"type":"journal"},"license":"public-domain","license_id":"https://openalex.org/licenses/public-domain","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"American Journal of Physiology-Heart and Circulatory Physiology","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5108514970","display_name":"Hideki Kumamoto","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I205349734","display_name":"Hokkaido University","ror":"https://ror.org/02e16g702","country_code":"JP","type":"education","lineage":["https://openalex.org/I205349734"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Hideki Kumamoto","raw_affiliation_strings":["Department of Cardiovascular Medicine,","Department of Cardiovascular Medicine, Hokkaido University, Kita-ku, Sapporo 060-8638, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cardiovascular Medicine,","institution_ids":[]},{"raw_affiliation_string":"Department of Cardiovascular Medicine, Hokkaido University, Kita-ku, Sapporo 060-8638, Japan","institution_ids":["https://openalex.org/I205349734"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Hiroshi Okamoto","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Hiroshi Okamoto","raw_affiliation_strings":["Department of Cardiovascular Medicine,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cardiovascular Medicine,","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101767263","display_name":"Masashi Watanabe","orcid":"https://orcid.org/0009-0006-5059-5518","observed_orcids":["https://orcid.org/0009-0006-5059-5518"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Masashi Watanabe","raw_affiliation_strings":["Department of Cardiovascular Medicine,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cardiovascular Medicine,","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5041252715","display_name":"Hisao Onozuka","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Hisao Onozuka","raw_affiliation_strings":["Department of Cardiovascular Medicine,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cardiovascular Medicine,","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5035723767","display_name":"Keiji Yoneya","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Keiji Yoneya","raw_affiliation_strings":["Department of Cardiovascular Medicine,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cardiovascular Medicine,","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112262660","display_name":"Izumi Nakagawa","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Izumi Nakagawa","raw_affiliation_strings":["Department of Cardiovascular Medicine,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cardiovascular Medicine,","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5083221298","display_name":"Satoru Chiba","orcid":"https://orcid.org/0000-0003-0041-6316","observed_orcids":["https://orcid.org/0000-0003-0041-6316","https://orcid.org/0000-0002-1545-3083"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Satoru Chiba","raw_affiliation_strings":["Department of Cardiovascular Medicine,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cardiovascular Medicine,","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101556359","display_name":"Satoshi Watanabe","orcid":"https://orcid.org/0009-0009-4585-6797","observed_orcids":["https://orcid.org/0009-0009-4585-6797"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Satoshi Watanabe","raw_affiliation_strings":["Department of Anatomy, School of Medicine, and"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Anatomy, School of Medicine, and","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101101467","display_name":"Taisei Mikami","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I205349734","display_name":"Hokkaido University","ror":"https://ror.org/02e16g702","country_code":"JP","type":"education","lineage":["https://openalex.org/I205349734"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Taisei Mikami","raw_affiliation_strings":["College of Medical Technology, Hokkaido University, Kita-ku, Sapporo 060-8638, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"College of Medical Technology, Hokkaido University, Kita-ku, Sapporo 060-8638, Japan","institution_ids":["https://openalex.org/I205349734"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5008483997","display_name":"Kazuhiro Abe","orcid":"https://orcid.org/0000-0003-2681-5921","observed_orcids":["https://orcid.org/0000-0003-2681-5921"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Kazuhiro Abe","raw_affiliation_strings":["Department of Anatomy, School of Medicine, and"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Anatomy, School of Medicine, and","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5111820422","display_name":"Akira Kitabatake","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Akira Kitabatake","raw_affiliation_strings":["Department of Cardiovascular Medicine,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cardiovascular Medicine,","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":1.4434,"has_fulltext":false,"cited_by_count":26,"citation_normalized_percentile":{"value":0.82055621,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":95},"biblio":{"volume":"276","issue":"4","first_page":"H1117","last_page":"H1123"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11962","display_name":"Cardiac Fibrosis and Remodeling","score":0.7339000105857849,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11962","display_name":"Cardiac Fibrosis and Remodeling","score":0.7339000105857849,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10882","display_name":"Cardiomyopathy and Myosin Studies","score":0.06989999860525131,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10821","display_name":"Cardiovascular Function and Risk Factors","score":0.04800000041723251,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/myocardial-angiogenesis","display_name":"myocardial angiogenesis","score":0.968999981880188},{"id":"https://openalex.org/keywords/cardiac-remodeling","display_name":"cardiac remodeling","score":0.9829999804496765},{"id":"https://openalex.org/keywords/dilated-cardiomyopathy","display_name":"dilated cardiomyopathy","score":0.9459999799728394},{"id":"https://openalex.org/keywords/amlodipine","display_name":"amlodipine","score":0.9819999933242798},{"id":"https://openalex.org/keywords/mci-154","display_name":"MCI-154","score":0.9860000014305115},{"id":"https://openalex.org/keywords/calcium-sensitizers","display_name":"calcium sensitizers","score":0.7400000095367432},{"id":"https://openalex.org/keywords/coronary-microcirculation","display_name":"coronary microcirculation","score":0.8180000185966492},{"id":"https://openalex.org/keywords/capillary-density","display_name":"capillary density","score":0.9110000133514404},{"id":"https://openalex.org/keywords/vascular-endothelial-growth-factor","display_name":"vascular endothelial growth factor","score":0.9200000166893005},{"id":"https://openalex.org/keywords/diastolic-function","display_name":"diastolic function","score":0.7770000100135803},{"id":"https://openalex.org/keywords/systolic-function","display_name":"systolic function","score":0.8420000076293945},{"id":"https://openalex.org/keywords/hamster-heart","display_name":"hamster heart","score":0.597000002861023}],"concepts":[{"id":"https://openalex.org/C2779646130","wikidata":"https://www.wikidata.org/wiki/Q411347","display_name":"Amlodipine","level":3,"score":0.9376423358917236},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.7445296049118042},{"id":"https://openalex.org/C164705383","wikidata":"https://www.wikidata.org/wiki/Q10379","display_name":"Cardiology","level":1,"score":0.6557817459106445},{"id":"https://openalex.org/C57900726","wikidata":"https://www.wikidata.org/wiki/Q492905","display_name":"Diastole","level":3,"score":0.639590322971344},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.5815836787223816},{"id":"https://openalex.org/C2780394083","wikidata":"https://www.wikidata.org/wiki/Q539568","display_name":"Angiogenesis","level":2,"score":0.5129587054252625},{"id":"https://openalex.org/C111566952","wikidata":"https://www.wikidata.org/wiki/Q1303462","display_name":"Cardiac function curve","level":3,"score":0.48625361919403076},{"id":"https://openalex.org/C2778575167","wikidata":"https://www.wikidata.org/wiki/Q6573","display_name":"Hamster","level":2,"score":0.45505836606025696},{"id":"https://openalex.org/C2780972559","wikidata":"https://www.wikidata.org/wiki/Q550061","display_name":"Endothelial dysfunction","level":2,"score":0.4386034309864044},{"id":"https://openalex.org/C178853913","wikidata":"https://www.wikidata.org/wiki/Q1642137","display_name":"Hemodynamics","level":2,"score":0.41657203435897827},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.34932440519332886},{"id":"https://openalex.org/C2778198053","wikidata":"https://www.wikidata.org/wiki/Q181754","display_name":"Heart failure","level":2,"score":0.22769564390182495},{"id":"https://openalex.org/C84393581","wikidata":"https://www.wikidata.org/wiki/Q82642","display_name":"Blood pressure","level":2,"score":0.2099955677986145}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002121","descriptor_name":"Calcium Channel Blockers","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D002196","descriptor_name":"Capillaries","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D002196","descriptor_name":"Capillaries","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D002311","descriptor_name":"Cardiomyopathy, Dilated","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D002311","descriptor_name":"Cardiomyopathy, Dilated","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":true},{"descriptor_ui":"D002316","descriptor_name":"Cardiotonic Agents","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D003326","descriptor_name":"Coronary Circulation","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D004452","descriptor_name":"Echocardiography","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006224","descriptor_name":"Cricetinae","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008222","descriptor_name":"Lymphokines","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009200","descriptor_name":"Myocardial Contraction","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D011724","descriptor_name":"Pyridazines","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D012333","descriptor_name":"RNA, Messenger","qualifier_ui":"Q000037","qualifier_name":"antagonists & inhibitors","is_major_topic":false},{"descriptor_ui":"D012333","descriptor_name":"RNA, Messenger","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D016228","descriptor_name":"Endothelial Growth Factors","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D016277","descriptor_name":"Ventricular Function, Left","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D017311","descriptor_name":"Amlodipine","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D018919","descriptor_name":"Neovascularization, Physiologic","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D020257","descriptor_name":"Ventricular Remodeling","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D042442","descriptor_name":"Vascular Endothelial Growth Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D042461","descriptor_name":"Vascular Endothelial Growth Factor A","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1152/ajpheart.1999.276.4.h1117","doi":"https://doi.org/10.1152/ajpheart.1999.276.4.h1117","is_oa":false,"landing_page_url":"https://doi.org/10.1152/ajpheart.1999.276.4.h1117","pdf_url":null,"source":{"id":"https://openalex.org/S87338489","display_name":"American Journal of Physiology-Heart and Circulatory Physiology","issn_l":"0363-6135","issn":["0363-6135","1522-1539"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-a","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320261","host_organization_name":"American Physical Society","host_organization_lineage":["https://openalex.org/P4310320261"],"host_organization_lineage_names":["American Physical Society"],"type":"journal"},"license":"public-domain","license_id":"https://openalex.org/licenses/public-domain","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"American Journal of Physiology-Heart and Circulatory Physiology","raw_type":"journal-article"},{"id":"pmid:10199832","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/10199832","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The American journal of physiology","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.98580002784729,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":31,"referenced_works":["https://openalex.org/W1860023717","https://openalex.org/W1968850832","https://openalex.org/W1979852829","https://openalex.org/W1985292788","https://openalex.org/W1997622882","https://openalex.org/W1999223106","https://openalex.org/W2004348481","https://openalex.org/W2007078312","https://openalex.org/W2011603125","https://openalex.org/W2016126378","https://openalex.org/W2018484541","https://openalex.org/W2026798725","https://openalex.org/W2034467669","https://openalex.org/W2039022783","https://openalex.org/W2053483133","https://openalex.org/W2056187351","https://openalex.org/W2058651524","https://openalex.org/W2070726999","https://openalex.org/W2072446438","https://openalex.org/W2086108055","https://openalex.org/W2089364073","https://openalex.org/W2091695537","https://openalex.org/W2113545946","https://openalex.org/W2126360708","https://openalex.org/W2166169771","https://openalex.org/W2261014181","https://openalex.org/W2318480619","https://openalex.org/W2319534362","https://openalex.org/W2346048525","https://openalex.org/W4255082845","https://openalex.org/W4301342942"],"related_works":["https://openalex.org/W4234642707","https://openalex.org/W2016126378","https://openalex.org/W2379161615","https://openalex.org/W2313974337","https://openalex.org/W2056359280","https://openalex.org/W167122637","https://openalex.org/W2090819947","https://openalex.org/W2034467669","https://openalex.org/W2004464684","https://openalex.org/W1998823663"],"abstract_inverted_index":{"The":[0],"present":[1],"study":[2,82,100],"examined":[3],"the":[4,23,44,85,91,124,138,159],"effect":[5],"of":[6,31,46,126,140,166,173],"long-term":[7],"treatment":[8,30],"with":[9,36],"amlodipine":[10,37,49,111,151],"and":[11,20,50,64,71,108,112,123,152,162,176],"MCI-154":[12,39,51,113],"(a":[13],"Ca2+":[14],"sensitizer)":[15],"on":[16],"progressive":[17],"cardiac":[18,174],"dysfunction":[19],"microvasculature":[21,157],"in":[22,58,66,75,90,116,158],"dilated":[24],"cardiomyopathic":[25],"(DCM)":[26],"hamster":[27,161],"heart.":[28],"After":[29],"DCM":[32,160],"hamsters":[33],"(Bio":[34],"53.58)":[35],"or":[38],"for":[40,142],"15":[41],"wk":[42],"from":[43],"age":[45],"5":[47],"wk,":[48],"were":[52],"found":[53],"to":[54,171],"cause":[55],"an":[56],"increase":[57],"left":[59,67],"ventricular":[60,68],"percent":[61],"fractional":[62],"shortening":[63],"decreases":[65],"diastolic":[69,86,177],"dimension":[70],"isovolumic":[72],"relaxation":[73],"time":[74,87],"echocardiograms":[76],"(P":[77,94,120,129],"<":[78,95,121,130],"0.01).":[79],"A":[80],"hemodynamic":[81],"showed":[83,136],"that":[84,105,137],"constant":[88],"decreased":[89],"amlodipine-treatment":[92],"group":[93],"0.05).":[96,131],"In":[97],"a":[98,102],"morphometric":[99],"employing":[101],"double-staining":[103],"method":[104],"discriminated":[106],"arteriolar":[107],"venular":[109,127],"capillaries,":[110],"caused":[114],"increases":[115],"total":[117],"capillary":[118],"density":[119],"0.05)":[122],"proportion":[125],"capillaries":[128],"Moreover,":[132],"Northern":[133],"blot":[134],"analysis":[135],"expression":[139],"mRNA":[141],"vascular":[143],"endothelial":[144],"growth":[145],"factor":[146],"was":[147],"significantly":[148],"increased":[149],"by":[150],"MCI-154.":[153],"They":[154],"preserve":[155],"coronary":[156],"might":[163],"induce":[164],"angiogenesis":[165],"small":[167],"vessels,":[168],"thereby":[169],"contributing":[170],"preservation":[172],"systolic":[175],"function.":[178]},"counts_by_year":[{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":1},{"year":2018,"cited_by_count":1},{"year":2016,"cited_by_count":1},{"year":2015,"cited_by_count":1},{"year":2014,"cited_by_count":1},{"year":2012,"cited_by_count":2}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2016-06-24T00:00:00"}