{"id":"https://openalex.org/W2124709554","doi":"https://doi.org/10.2485/jhtb.22.7","title":"HSP70 Expression in the Mouse Dental Pulp after Immediate Teeth Separation","display_name":"HSP70 Expression in the Mouse Dental Pulp after Immediate Teeth Separation","publication_year":2013,"publication_date":"2013-01-01","ids":{"openalex":"https://openalex.org/W2124709554","doi":"https://doi.org/10.2485/jhtb.22.7","mag":"2124709554"},"language":"en","primary_location":{"id":"doi:10.2485/jhtb.22.7","doi":"https://doi.org/10.2485/jhtb.22.7","is_oa":true,"landing_page_url":"https://doi.org/10.2485/jhtb.22.7","pdf_url":"https://www.jstage.jst.go.jp/article/jhtb/22/1/22_7/_pdf","source":{"id":"https://openalex.org/S39874079","display_name":"Journal of Hard Tissue Biology","issn_l":"1341-7649","issn":["1341-7649","1880-828X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","jufo-1","poland-40","russia-white-list-3"],"host_organization":"https://openalex.org/P4376882122","host_organization_name":"Japanese Society of Hard Tissue Research and Technology","host_organization_lineage":["https://openalex.org/P4376882122"],"host_organization_lineage_names":["Japanese Society of Hard Tissue Research and Technology"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Hard Tissue Biology","raw_type":"journal-article"},"parent_works":[],"lineage":["https://openalex.org/W2124709554"],"child_works_count":0,"type":"article","is_traditional":true,"indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://www.jstage.jst.go.jp/article/jhtb/22/1/22_7/_pdf","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5023061079","display_name":"Keisuke Nakano","orcid":"https://orcid.org/0000-0001-8316-8543","observed_orcids":["https://orcid.org/0000-0001-8316-8543"]},"institutions":[{"id":"https://openalex.org/I90960554","display_name":"Matsumoto Dental University","ror":"https://ror.org/041jyt122","country_code":"JP","type":"education","lineage":["https://openalex.org/I90960554"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Keisuke Nakano","raw_affiliation_strings":["Hard Tissue Pathology Unit, Matsumoto Dental University Graduate School of Oral Medicine"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Hard Tissue Pathology Unit, Matsumoto Dental University Graduate School of Oral Medicine","institution_ids":["https://openalex.org/I90960554"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111705236","display_name":"Shinnosuke Saito","orcid":"https://orcid.org/0009-0008-5537-0865","observed_orcids":["https://orcid.org/0009-0008-5537-0865"]},"institutions":[{"id":"https://openalex.org/I90960554","display_name":"Matsumoto Dental University","ror":"https://ror.org/041jyt122","country_code":"JP","type":"education","lineage":["https://openalex.org/I90960554"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Shinnosuke Saito","raw_affiliation_strings":["Oral Health Analysis Unit, Matsumoto Dental University Graduate School of Oral Medicine"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Oral Health Analysis Unit, Matsumoto Dental University Graduate School of Oral Medicine","institution_ids":["https://openalex.org/I90960554"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5067430560","display_name":"Atsushi Nabeyama","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I90960554","display_name":"Matsumoto Dental University","ror":"https://ror.org/041jyt122","country_code":"JP","type":"education","lineage":["https://openalex.org/I90960554"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Atsushi Nabeyama","raw_affiliation_strings":["Hard Tissue Pathology Unit, Matsumoto Dental University Graduate School of Oral Medicine"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Hard Tissue Pathology Unit, Matsumoto Dental University Graduate School of Oral Medicine","institution_ids":["https://openalex.org/I90960554"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5011066825","display_name":"S Oishi","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I90960554","display_name":"Matsumoto Dental University","ror":"https://ror.org/041jyt122","country_code":"JP","type":"education","lineage":["https://openalex.org/I90960554"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Shintaro Oishi","raw_affiliation_strings":["Department of Endodontics and Operative Dentistry, Matsumoto Dental University School of Dentistry","Hard Tissue Pathology Unit, Matsumoto Dental University Graduate School of Oral Medicine"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Endodontics and Operative Dentistry, Matsumoto Dental University School of Dentistry","institution_ids":["https://openalex.org/I90960554"]},{"raw_affiliation_string":"Hard Tissue Pathology Unit, Matsumoto Dental University Graduate School of Oral Medicine","institution_ids":["https://openalex.org/I90960554"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5102872850","display_name":"Masahiro Sato","orcid":"https://orcid.org/0000-0001-9679-5212","observed_orcids":["https://orcid.org/0000-0001-9679-5212"]},"institutions":[{"id":"https://openalex.org/I90960554","display_name":"Matsumoto Dental University","ror":"https://ror.org/041jyt122","country_code":"JP","type":"education","lineage":["https://openalex.org/I90960554"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Masahiro Sato","raw_affiliation_strings":["Department of Endodontics and Operative Dentistry, Matsumoto Dental University School of Dentistry"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Endodontics and Operative Dentistry, Matsumoto Dental University School of Dentistry","institution_ids":["https://openalex.org/I90960554"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5064465922","display_name":"Yukiko Yokoi","orcid":"https://orcid.org/0000-0002-9277-5836","observed_orcids":["https://orcid.org/0000-0002-9277-5836"]},"institutions":[{"id":"https://openalex.org/I90960554","display_name":"Matsumoto Dental University","ror":"https://ror.org/041jyt122","country_code":"JP","type":"education","lineage":["https://openalex.org/I90960554"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Yukiko Yokoi","raw_affiliation_strings":["Department of Pediatric Dentistry, Matsumoto Dental University School of Dentistry"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pediatric Dentistry, Matsumoto Dental University School of Dentistry","institution_ids":["https://openalex.org/I90960554"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5035952112","display_name":"Naoto Osuga","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I90960554","display_name":"Matsumoto Dental University","ror":"https://ror.org/041jyt122","country_code":"JP","type":"education","lineage":["https://openalex.org/I90960554"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Naoto Osuga","raw_affiliation_strings":["Department of Pediatric Dentistry, Matsumoto Dental University School of Dentistry","Oral Health Analysis Unit, Matsumoto Dental University Graduate School of Oral Medicine"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pediatric Dentistry, Matsumoto Dental University School of Dentistry","institution_ids":["https://openalex.org/I90960554"]},{"raw_affiliation_string":"Oral Health Analysis Unit, Matsumoto Dental University Graduate School of Oral Medicine","institution_ids":["https://openalex.org/I90960554"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5069120233","display_name":"Norimasa Okafuji","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I90960554","display_name":"Matsumoto Dental University","ror":"https://ror.org/041jyt122","country_code":"JP","type":"education","lineage":["https://openalex.org/I90960554"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Norimasa Okafuji","raw_affiliation_strings":["Clinical Evaluation Unit, Matsumoto Dental University Graduate School of Oral Medicine"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Clinical Evaluation Unit, Matsumoto Dental University Graduate School of Oral Medicine","institution_ids":["https://openalex.org/I90960554"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5068254016","display_name":"Toshiyuki Kawakami","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I90960554","display_name":"Matsumoto Dental University","ror":"https://ror.org/041jyt122","country_code":"JP","type":"education","lineage":["https://openalex.org/I90960554"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Toshiyuki Kawakami","raw_affiliation_strings":["Hard Tissue Pathology Unit, Matsumoto Dental University Graduate School of Oral Medicine"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Hard Tissue Pathology Unit, Matsumoto Dental University Graduate School of Oral Medicine","institution_ids":["https://openalex.org/I90960554"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I90960554"],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":true,"cited_by_count":2,"citation_normalized_percentile":{"value":0.0,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":93},"biblio":{"volume":"22","issue":"1","first_page":"7","last_page":"12"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10934","display_name":"Heat shock proteins research","score":0.4138000011444092,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10934","display_name":"Heat shock proteins research","score":0.4138000011444092,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10536","display_name":"Endodontics and Root Canal Treatments","score":0.3582000136375427,"subfield":{"id":"https://openalex.org/subfields/3504","display_name":"Oral Surgery"},"field":{"id":"https://openalex.org/fields/35","display_name":"Dentistry"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12367","display_name":"Dental Trauma and Treatments","score":0.048700001090765,"subfield":{"id":"https://openalex.org/subfields/3500","display_name":"General Dentistry"},"field":{"id":"https://openalex.org/fields/35","display_name":"Dentistry"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/hsp70","display_name":"HSP70","score":0.9860000014305115},{"id":"https://openalex.org/keywords/heat-shock-proteins","display_name":"heat shock proteins","score":0.7910000085830688},{"id":"https://openalex.org/keywords/dental-pulp","display_name":"dental pulp","score":0.996999979019165},{"id":"https://openalex.org/keywords/tooth-separation","display_name":"tooth separation","score":0.7429999709129333},{"id":"https://openalex.org/keywords/conservative-dental-treatment","display_name":"conservative dental treatment","score":0.7820000052452087},{"id":"https://openalex.org/keywords/pulp-injury","display_name":"pulp injury","score":0.4440000057220459},{"id":"https://openalex.org/keywords/mouse-model","display_name":"mouse model","score":0.3490000069141388}],"concepts":[{"id":"https://openalex.org/C204232928","wikidata":"https://www.wikidata.org/wiki/Q899285","display_name":"Immunohistochemistry","level":2,"score":0.705246090888977},{"id":"https://openalex.org/C202271784","wikidata":"https://www.wikidata.org/wiki/Q189218","display_name":"Molar","level":2,"score":0.6767528057098389},{"id":"https://openalex.org/C188442228","wikidata":"https://www.wikidata.org/wiki/Q48286","display_name":"Pulp (tooth)","level":2,"score":0.660419225692749},{"id":"https://openalex.org/C199343813","wikidata":"https://www.wikidata.org/wiki/Q12128","display_name":"Dentistry","level":1,"score":0.6395986676216125},{"id":"https://openalex.org/C68991219","wikidata":"https://www.wikidata.org/wiki/Q419102","display_name":"Hsp70","level":4,"score":0.5555562376976013},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.5115476846694946},{"id":"https://openalex.org/C29694066","wikidata":"https://www.wikidata.org/wiki/Q118301","display_name":"Orthodontics","level":1,"score":0.3314269483089447},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.26202189922332764},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.20983269810676575},{"id":"https://openalex.org/C205260736","wikidata":"https://www.wikidata.org/wiki/Q418939","display_name":"Heat shock protein","level":3,"score":0.059893280267715454},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.2485/jhtb.22.7","doi":"https://doi.org/10.2485/jhtb.22.7","is_oa":true,"landing_page_url":"https://doi.org/10.2485/jhtb.22.7","pdf_url":"https://www.jstage.jst.go.jp/article/jhtb/22/1/22_7/_pdf","source":{"id":"https://openalex.org/S39874079","display_name":"Journal of Hard Tissue Biology","issn_l":"1341-7649","issn":["1341-7649","1880-828X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","jufo-1","poland-40","russia-white-list-3"],"host_organization":"https://openalex.org/P4376882122","host_organization_name":"Japanese Society of Hard Tissue Research and Technology","host_organization_lineage":["https://openalex.org/P4376882122"],"host_organization_lineage_names":["Japanese Society of Hard Tissue Research and Technology"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Hard Tissue Biology","raw_type":"journal-article"}],"best_oa_location":{"id":"doi:10.2485/jhtb.22.7","doi":"https://doi.org/10.2485/jhtb.22.7","is_oa":true,"landing_page_url":"https://doi.org/10.2485/jhtb.22.7","pdf_url":"https://www.jstage.jst.go.jp/article/jhtb/22/1/22_7/_pdf","source":{"id":"https://openalex.org/S39874079","display_name":"Journal of Hard Tissue Biology","issn_l":"1341-7649","issn":["1341-7649","1880-828X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","jufo-1","poland-40","russia-white-list-3"],"host_organization":"https://openalex.org/P4376882122","host_organization_name":"Japanese Society of Hard Tissue Research and Technology","host_organization_lineage":["https://openalex.org/P4376882122"],"host_organization_lineage_names":["Japanese Society of Hard Tissue Research and Technology"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Hard Tissue Biology","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.9391000270843506,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G1350973022","display_name":"Molecular control mechanism of cell suppling, migration and differentiation in remodeling of periodontal ligament","funder_award_id":"25463204","funder_id":"https://openalex.org/F4320334764","funder_display_name":"Japan Society for the Promotion of Science"},{"id":"https://openalex.org/G406492257","display_name":"Elucidation of the cell differentiation molecular regulation mechanism in proliferative lesions of the oral cavity using bone marrow stem cell transplantation model","funder_award_id":"23592951","funder_id":"https://openalex.org/F4320334764","funder_display_name":"Japan Society for the Promotion of Science"},{"id":"https://openalex.org/G4690172706","display_name":"\u50b7\u5bb3\u6027\u30b9\u30c8\u30ec\u30b9\u306b\u5bfe\u3059\u308b\u6b6f\u9ac4\u7d30\u80de\u306e\u6052\u5e38\u6027\u7dad\u6301\u3068\u56de\u5fa9\u53cd\u5fdc\u306b\u95a2\u3059\u308b\u5206\u5b50\u6a5f\u69cb\u306e\u89e3\u660e","funder_award_id":"24792048","funder_id":"https://openalex.org/F4320334764","funder_display_name":"Japan Society for the Promotion of Science"},{"id":"https://openalex.org/G6010070158","display_name":"Elucidation of the molecular mechanisms of tissue repair using stem cells","funder_award_id":"23593075","funder_id":"https://openalex.org/F4320334764","funder_display_name":"Japan Society for the Promotion of Science"},{"id":"https://openalex.org/G7936669808","display_name":"Elucidation of molecular regulation mechanism and promotion of the orthodontic remodeling using the bone marrow stem cell","funder_award_id":"22592303","funder_id":"https://openalex.org/F4320334764","funder_display_name":"Japan Society for the Promotion of Science"}],"funders":[{"id":"https://openalex.org/F4320334764","display_name":"Japan Society for the Promotion of Science","ror":"https://ror.org/00hhkn466"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2124709554.pdf","grobid_xml":"https://content.openalex.org/works/W2124709554.grobid-xml"},"referenced_works_count":15,"referenced_works":["https://openalex.org/W1994897684","https://openalex.org/W1996497691","https://openalex.org/W2005572347","https://openalex.org/W2010586545","https://openalex.org/W2015644766","https://openalex.org/W2025240885","https://openalex.org/W2034310517","https://openalex.org/W2066280415","https://openalex.org/W2104755183","https://openalex.org/W2113903428","https://openalex.org/W2146704136","https://openalex.org/W2153335102","https://openalex.org/W2153744789","https://openalex.org/W2331780222","https://openalex.org/W2333480248"],"related_works":["https://openalex.org/W2153744789","https://openalex.org/W2355957115","https://openalex.org/W2282771217","https://openalex.org/W2370080846","https://openalex.org/W2347222771","https://openalex.org/W2056326760","https://openalex.org/W2380581554","https://openalex.org/W2354756135","https://openalex.org/W2380797145","https://openalex.org/W2331780222"],"abstract_inverted_index":{"We":[0],"examined":[1],"the":[2,8,51,58,65,79,82],"change":[3],"of":[4,81,95,110],"HSP70":[5,54,96],"expression":[6,55,63,94],"in":[7,57],"mouse":[9],"dental":[10,26,59],"pulp":[11,60],"which":[12,71],"was":[13,39,64],"exposed":[14],"to":[15,75,78],"experimental":[16,52],"teeth":[17],"separation":[18],"by":[19],"immunohistochemistry":[20],"as":[21,99],"a":[22,37,111],"model":[23],"for":[24,47],"conservative":[25],"treatment.":[27],"Eight":[28],"week-old":[29],"18":[30],"male":[31],"ddY":[32],"mice":[33],"were":[34],"used":[35,98],"and":[36,44],"wedge":[38,112],"inserted":[40],"between":[41],"upper":[42],"1st":[43],"2nd":[45],"molars":[46],"3":[48],"hours.":[49],"In":[50],"group,":[53],"increased":[56],"tissues.":[61],"The":[62],"greatest":[66],"at":[67,85],"24":[68],"hours":[69],"after":[70],"it":[72],"gradually":[73],"decreased":[74],"become":[76],"similar":[77],"level":[80],"control":[83],"group":[84],"1":[86],"week.":[87],"These":[88],"results":[89],"suggest":[90],"that":[91],"when":[92],"immunohistochemical":[93],"is":[97],"an":[100],"index,":[101],"almost":[102],"no":[103],"severe":[104],"damage":[105],"occurs":[106],"upon":[107],"clinical":[108],"application":[109],"insertion.":[113]},"counts_by_year":[{"year":2019,"cited_by_count":1},{"year":2018,"cited_by_count":1}],"updated_date":"2026-09-21T07:43:02.447757","created_date":"2016-06-24T00:00:00"}